Detailed information for compound 115367

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 352.45 | Formula: C20H20N2O2S
  • H donors: 0 H acceptors: 3 LogP: 4.27 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC/C=C/c1nn(c(c1)c1ccc(cc1)S(=O)(=O)C)c1ccccc1
  • InChi: 1S/C20H20N2O2S/c1-3-4-8-17-15-20(22(21-17)18-9-6-5-7-10-18)16-11-13-19(14-12-16)25(2,23)24/h4-15H,3H2,1-2H3/b8-4+
  • InChiKey: CGUZOYFGHICCSV-XBXARRHUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi isocitrate dehydrogenase 0.0017 0.0019 0.0022
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0234 0.0237
Echinococcus granulosus flap endonuclease 1 0.0028 0.0148 0.0149
Schistosoma mansoni biogenic amine receptor 0.0038 0.0262 0.0299
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0053 0.044 0.2005
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0023 0.0091 0.072
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0038 0.0262 0.0299
Brugia malayi steroid hormone receptor 0.0067 0.0604 0.0735
Leishmania major P-type ATPase, putative 0.0042 0.0316 0.14
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0001 0.000000059439
Echinococcus granulosus mannose 6 phosphate isomerase 0.0094 0.0922 0.0938
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0262 0.0261
Toxoplasma gondii phosphomannose isomerase type I protein 0.0094 0.0922 1
Echinococcus granulosus G protein coupled receptor 139 0.0038 0.0262 0.0266
Onchocerca volvulus Protein ultraspiracle homolog 0.0067 0.0604 0.069
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0019 0.0033
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.132 0.1509
Loa Loa (eye worm) hypothetical protein 0.0035 0.0234 0.0267
Loa Loa (eye worm) hypothetical protein 0.0032 0.019 0.0216
Leishmania major calcium-translocating P-type ATPase 0.0053 0.044 0.1977
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0053 0.044 0.0775
Echinococcus granulosus cation transporting ATPase 13A3 0.0017 0.0016 0.0015
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0033 0.0036
Echinococcus multilocularis protein patched 0.0045 0.0351 0.035
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0038 0.0262 0.0261
Schistosoma mansoni type V p-type atpase isoform 0.0017 0.0016 0.0017
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0112 0.1131 0.1217
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0067 0.0604 0.0735
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0424 0.4789 0.5483
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0038 0.0262 0.0266
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0089 0.0133
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0067 0.0604 0.0735
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0148 0.1427
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0148 0.0615
Echinococcus multilocularis expressed conserved protein 0.0099 0.0982 0.0981
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0126 0.02
Brugia malayi hypothetical protein 0.0038 0.0262 0.0318
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0038 0.0262 0.0299
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.019 0.0189
Onchocerca volvulus 0.0053 0.0442 0.0504
Loa Loa (eye worm) hypothetical protein 0.0032 0.019 0.0216
Trypanosoma cruzi P-type H+-ATPase, putative 0.0034 0.0215 0.2151
Echinococcus granulosus neuropeptide receptor 0.0038 0.0262 0.0266
Echinococcus granulosus GA binding protein alpha chain 0.0078 0.073 0.0742
Echinococcus granulosus intermediate filament protein 0.0055 0.0471 0.0478
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0262 0.0299
Schistosoma mansoni flap endonuclease-1 0.0025 0.0117 0.0132
Loa Loa (eye worm) hypothetical protein 0.0067 0.0604 0.069
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Schistosoma mansoni intermediate filament proteins 0.0055 0.0471 0.0537
Entamoeba histolytica mannose-6-phosphate isomerase, putative 0.0043 0.0325 0.2967
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0025 0.0118 0.11
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0262 0.0266
Trichomonas vaginalis set domain proteins, putative 0.0483 0.5476 1
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0026 0.0126 0.0142
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0234 0.0237
Loa Loa (eye worm) steroid hormone receptor 0.0067 0.0604 0.069
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0001 0.00000006055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0067 0.0604 0.069
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0026 0.0126 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0135 0.0136
Loa Loa (eye worm) hypothetical protein 0.0121 0.1235 0.1412
Schistosoma mansoni opsin-like receptor 0.0038 0.0262 0.0299
Echinococcus granulosus calcium transporting atpase 0.0042 0.0316 0.0321
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0019 0.0018
Echinococcus multilocularis sex peptide receptor 0.0038 0.0262 0.0261
Loa Loa (eye worm) hypothetical protein 0.0715 0.8195 0.9382
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0067 0.0604 0.0613
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0042 0.0316 0.0321
Echinococcus multilocularis geminin 0.0348 0.3903 0.3902
Brugia malayi beta-lactamase 0.0035 0.0234 0.0284
Schistosoma mansoni cation-transporting atpase worm 0.0017 0.0016 0.0017
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0067 0.0604 0.0613
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0038 0.0262 0.0318
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0262 0.0299
Echinococcus multilocularis jun protein 0.0083 0.079 0.0789
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0234 0.0399
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0053 0.044 0.0775
Echinococcus granulosus serotonin receptor 0.0038 0.0262 0.0266
Schistosoma mansoni neuropeptide receptor 0.0038 0.0262 0.0299
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0447 0.0544
Echinococcus granulosus allatostatin A receptor 0.0038 0.0262 0.0266
Schistosoma mansoni neuropeptide receptor 0.0038 0.0262 0.0299
Schistosoma mansoni neuropeptide receptor 0.0038 0.0262 0.0299
Mycobacterium tuberculosis Conserved protein 0.0035 0.0234 0.0237
Trichomonas vaginalis cation-transporting ATPase, putative 0.0053 0.044 0.0775
Loa Loa (eye worm) hypothetical protein 0.0032 0.019 0.0216
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0234 0.0399
Brugia malayi nuclear hormone receptor family member odr-7 0.0032 0.019 0.023
Toxoplasma gondii P-type ATPase PMA1 0.0034 0.0215 0.2329
Loa Loa (eye worm) hypothetical protein 0.034 0.3803 0.4353
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0042 0.0316 0.0549
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0262 0.0299
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0053 0.044 0.4069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0067 0.0604 0.069
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0038 0.0262 0.0261
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0089 0.0087
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0468 0.53 0.6067
Loa Loa (eye worm) hypothetical protein 0.0067 0.0604 0.069
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0078 0.073 0.0834
Echinococcus granulosus orexin receptor type 2 0.0038 0.0262 0.0266
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0799 0.9181 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0262 0.0299
Brugia malayi Tachykinin-like peptides receptor 99D 0.0038 0.0262 0.0318
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Plasmodium falciparum mannose-6-phosphate isomerase, putative 0.0094 0.0922 1
Echinococcus multilocularis aryl hydrocarbon receptor 0.0026 0.0126 0.0124
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0019 0.0018
Onchocerca volvulus 0.0055 0.0471 0.0537
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0329 0.3675 0.4206
Schistosoma mansoni cation-transporting ATPase 0.0017 0.0016 0.0017
Loa Loa (eye worm) nuclear receptor NHR-67 0.0032 0.019 0.0216
Brugia malayi G protein-coupled receptor F59B2.13 0.0038 0.0262 0.0318
Onchocerca volvulus 0.0038 0.0262 0.0299
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0148 0.1605
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0053 0.044 0.4069
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0761 0.8734 0.8734
Leishmania major calcium-transporting ATPase, putative 0.0042 0.0316 0.14
Echinococcus granulosus neuropeptide s receptor 0.0038 0.0262 0.0266
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0234 0.0399
Onchocerca volvulus 0.0129 0.133 0.1521
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.0351 0.0401
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0745 0.0758
Brugia malayi Ets-domain containing protein 0.0078 0.073 0.0889
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0137 0.1313
Trypanosoma brucei phosphomannose isomerase 0.0094 0.0922 0.4289
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0262 0.0261
Plasmodium vivax P-type ATPase4, putative 0.0053 0.044 0.4758
Brugia malayi nuclear receptor NHR-88 0.0067 0.0604 0.0735
Schistosoma mansoni nuclear receptor 0.0032 0.019 0.0216
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0534 0.579
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0021
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.0604 0.0735
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0225 0.2459 0.2665
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.132 0.1509
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0042 0.0316 0.036
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0126 0.1185
Loa Loa (eye worm) hypothetical protein 0.0428 0.4835 0.5535
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0067 0.0604 0.0735
Brugia malayi hypothetical protein 0.0428 0.4835 0.59
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0035 0.0234 0.0267
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0023 0.0091 0.0812
Echinococcus multilocularis musashi 0.0055 0.0471 0.0469
Loa Loa (eye worm) hypothetical protein 0.0054 0.0459 0.0524
Brugia malayi calcium ATPase 0.0019 0.0046 0.0054
Echinococcus granulosus cation transporting ATPase 13A1 0.0017 0.0016 0.0015
Brugia malayi hypothetical protein 0.0035 0.0234 0.0284
Brugia malayi E1-E2 ATPase family protein 0.0017 0.0016 0.0018
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0262 0.0261
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0262 0.0261
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0336 0.3753 0.4296
Brugia malayi G protein-coupled receptor 0.0038 0.0262 0.0318
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0038 0.0262 0.0299
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0126 0.02
Leishmania major protein kinase, putative 0.0026 0.0126 0.051
Schistosoma mansoni mannose-6-phosphate isomerase 0.0094 0.0922 0.1054
Brugia malayi hypothetical protein 0.0035 0.0234 0.0284
Loa Loa (eye worm) hypothetical protein 0.0121 0.1235 0.1412
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0053 0.044 0.4676
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0148 0.0168
Brugia malayi neuropeptide F receptor 0.0038 0.0262 0.0318
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0017 0.0016 0.0015
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.002
Brugia malayi hypothetical protein 0.0038 0.0262 0.0318
Echinococcus multilocularis calcium transporting atpase 0.0042 0.0316 0.0315
Echinococcus multilocularis allatostatin A receptor 0.0038 0.0262 0.0261
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0534 0.0532
Trypanosoma brucei calcium-transporting ATPase, putative 0.0025 0.0118 0.048
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0067 0.0604 0.069
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Leishmania major phosphomannose isomerase 0.0094 0.0922 0.4228
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0038 0.0262 0.0299
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0067 0.0604 0.0602
Loa Loa (eye worm) hypothetical protein 0.0035 0.0234 0.0266
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0053 0.044 0.0775
Brugia malayi photoreceptor-specific nuclear receptor 0.0067 0.0604 0.0735
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0032 0.019 0.023
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0032 0.019 0.0216
Echinococcus granulosus GPCR family 2 0.0017 0.0019 0.0018
Onchocerca volvulus 0.0038 0.0262 0.0299
Entamoeba histolytica hypothetical protein 0.0039 0.0273 0.2464
Schistosoma mansoni copper ABC transporter ATPase 0.0017 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.0026 0.0123 0.0139
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0038 0.0262 0.0299
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0067 0.0604 0.0735
Brugia malayi hypothetical protein 0.0336 0.3753 0.4579
Brugia malayi calcium ATPase 0.0023 0.0091 0.0109
Trichomonas vaginalis mannose-6-phosphate isomerase, putative 0.0094 0.0922 0.1659
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0262 0.0261
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.0761 0.8734 0.8897
Loa Loa (eye worm) hypothetical protein 0.0035 0.0234 0.0266
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0053 0.044 0.0446
Brugia malayi hypothetical protein 0.0038 0.0262 0.0318
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0038 0.0262 0.0318
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0262 0.0261
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0118 0.1206 0.1379
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0019 0.0033
Toxoplasma gondii P-type ATPase4, putative 0.0053 0.044 0.477
Brugia malayi G-protein coupled receptor 0.0038 0.0262 0.0318
Brugia malayi ecdysone receptor 0.0032 0.019 0.023
Echinococcus multilocularis nervana 2 0.0468 0.53 0.5299
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Mycobacterium ulcerans lipase LipD 0.0035 0.0234 0.0237
Echinococcus multilocularis protein dispatched 1 0.0052 0.0426 0.0425
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0234 0.252
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0067 0.0604 0.0735
Schistosoma mansoni hypothetical protein 0.0038 0.0262 0.0299
Brugia malayi hypothetical protein 0.0715 0.8195 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Schistosoma mansoni hypothetical protein 0.0044 0.0332 0.0379
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0137 0.1313
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0067 0.0604 0.069
Loa Loa (eye worm) hypothetical protein 0.0023 0.0091 0.0103
Echinococcus granulosus Protein patched homolog 1 0.0045 0.0351 0.0356
Echinococcus granulosus lamin dm0 0.0055 0.0471 0.0478
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0745 0.0744
Schistosoma mansoni lamin 0.0055 0.0471 0.0537
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0135 0.0133
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0262 0.0261
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0053 0.044 0.2005
Echinococcus granulosus g-protein coupled receptor 0.0038 0.0262 0.0266
Loa Loa (eye worm) hypothetical protein 0.0067 0.0604 0.069
Loa Loa (eye worm) hypothetical protein 0.0032 0.019 0.0216
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0038 0.0262 0.0261
Plasmodium vivax SET domain protein, putative 0.0061 0.0534 0.578
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0026 0.0126 0.0124
Loa Loa (eye worm) hypoxia-induced factor 1 0.031 0.3448 0.3947
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0053 0.044 0.0446
Mycobacterium tuberculosis Conserved protein 0.0035 0.0234 0.0237
Brugia malayi nuclear receptor NHR-88 0.0032 0.019 0.023
Brugia malayi E1-E2 ATPase family protein 0.0034 0.0215 0.026
Echinococcus granulosus g protein coupled receptor 0.0038 0.0262 0.0266
Schistosoma mansoni opsin-like receptor 0.0038 0.0262 0.0299
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Schistosoma mansoni RAR-like nuclear receptor 0.0067 0.0604 0.069
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0053 0.044 0.4069
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0262 0.0299
Loa Loa (eye worm) hypothetical protein 0.0032 0.019 0.0216
Trypanosoma cruzi P-type H+-ATPase, putative 0.0023 0.0091 0.0812
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0023 0.0091 0.0812
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0038 0.0262 0.0299
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0118 0.1206 0.1205
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Mycobacterium ulcerans mannose-6-phosphate isomerase ManA 0.0094 0.0922 0.0988
Mycobacterium ulcerans hypothetical protein 0.0035 0.0234 0.0237
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0761 0.8734 1
Schistosoma mansoni hypothetical protein 0.0037 0.0249 0.0283
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0534 0.0542
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.003 0.017 0.0205
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0148 0.1265
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0262 0.0299
Entamoeba histolytica hypothetical protein 0.0039 0.0273 0.2464
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0262 0.0299
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0262 0.0299
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0262 0.0261
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Echinococcus granulosus dro:myosuppressin receptor 0.0038 0.0262 0.0266
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.0761 0.8734 0.8734
Echinococcus granulosus ecdysone induced protein 78C 0.0067 0.0604 0.0613
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0234 0.0266
Brugia malayi larval opioid receptor 0.0038 0.0262 0.0318
Echinococcus multilocularis neuropeptide FF receptor 2 0.0038 0.0262 0.0261
Trichomonas vaginalis cation-transporting ATPase, putative 0.0034 0.0215 0.0363
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0262 0.0299
Brugia malayi nuclear receptor NHR-67 0.0032 0.019 0.023
Schistosoma mansoni hypothetical protein 0.0038 0.0262 0.0299
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0094 0.0922 0.1054
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0137 0.1338
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0053 0.044 0.459
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0019 0.0014
Brugia malayi conserved hypotetical protein 0.0032 0.019 0.023
Schistosoma mansoni jun-related protein 0.0067 0.0608 0.0695
Onchocerca volvulus 0.0038 0.0262 0.0299
Echinococcus granulosus neuropeptide receptor A26 0.0038 0.0262 0.0266
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0053 0.044 0.459
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0262 0.0299
Brugia malayi Na,K-ATPase alpha subunit 0.0129 0.133 0.1621
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0112 0.1131 0.1294
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0053 0.044 0.0438
Loa Loa (eye worm) DR-78 0.0032 0.019 0.0216
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0137 0.1491
Echinococcus multilocularis GPCR, family 2 0.0017 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Echinococcus multilocularis lamin dm0 0.0055 0.0471 0.0469
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0083 0.079 0.0803
Brugia malayi hypothetical protein 0.0032 0.019 0.023
Loa Loa (eye worm) hypothetical protein 0.0067 0.0604 0.069
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0262 0.0266
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0262 0.0266
Echinococcus multilocularis microtubule associated protein 2 0.069 0.7907 0.7907
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0169 0.0205
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0262 0.0261
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0017
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0019 0.0018
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0067 0.0604 0.069
Echinococcus granulosus Nuclear hormone receptor HR96 0.0032 0.019 0.0192
Loa Loa (eye worm) melatonin receptor type 1A 0.0038 0.0262 0.0299
Trypanosoma cruzi phosphomannose isomerase, putative 0.0094 0.0922 0.9816
Brugia malayi Steroid receptor seven-up type 2 0.0067 0.0604 0.0735
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0126 0.1185
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0067 0.0604 0.0613
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0032 0.019 0.0189
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0053 0.044 0.459
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0262 0.0266
Treponema pallidum cation-transporting ATPase, P-type 0.0017 0.0016 0.5
Schistosoma mansoni ATPase 0.0053 0.044 0.0502
Onchocerca volvulus 0.0038 0.0262 0.0299
Brugia malayi bHLH-PAS transcription factor 0.0074 0.0688 0.0838
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0067 0.0604 0.0735
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0067 0.0604 0.069
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0017 0.0016 0.0177
Brugia malayi hypothetical protein 0.0039 0.0273 0.0331
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0032 0.019 0.0216
Schistosoma mansoni nuclear hormone receptor 0.0067 0.0604 0.069
Echinococcus multilocularis gamma secretase subunit aph 1 0.0245 0.2689 0.2688
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0094 0.0922 0.1054
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0234 0.2359
Onchocerca volvulus 0.0038 0.0262 0.0299
Echinococcus multilocularis neuropeptide s receptor 0.0038 0.0262 0.0261
Loa Loa (eye worm) hypothetical protein 0.0045 0.0351 0.0401
Echinococcus multilocularis serotonin receptor 0.0158 0.1667 0.1666
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0042 0.0316 0.0315
Loa Loa (eye worm) runx1 0.0054 0.045 0.0514
Trypanosoma cruzi Aph-1 protein, putative 0.0095 0.0939 1
Onchocerca volvulus 0.0483 0.5477 0.6271
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0468 0.53 0.5398
Onchocerca volvulus 0.0067 0.0604 0.069
Echinococcus granulosus Na:K ATPase alpha subunit 0.0118 0.1206 0.1227
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0053 0.044 0.0446
Schistosoma mansoni microtubule-associated protein tau 0.069 0.7907 0.9053
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.019 0.0216
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0042 0.0316 0.252
Brugia malayi PAS domain containing protein 0.01 0.0993 0.121
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0262 0.0299
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0234 0.0237
Echinococcus multilocularis mannose 6 phosphate isomerase 0.0094 0.0922 0.092
Echinococcus multilocularis Protein lozenge 0.0054 0.045 0.0449
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0032 0.019 0.0189
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0053 0.044 0.0775
Echinococcus multilocularis tumor protein p63 0.0362 0.4063 0.4062
Onchocerca volvulus 0.0038 0.0262 0.0299
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0234 0.0232
Echinococcus multilocularis conserved hypothetical protein 0.0679 0.7783 0.7783
Onchocerca volvulus 0.0038 0.0262 0.0299
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0032 0.019 0.0216
Brugia malayi Dopamine receptor 0.0038 0.0262 0.0318
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0019 0.021
Loa Loa (eye worm) hypothetical protein 0.0035 0.0234 0.0267
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0036 0.0241 0.0245
Brugia malayi follicle stimulating hormone receptor 0.0038 0.0262 0.0318
Echinococcus granulosus neuropeptide FF receptor 2 0.0038 0.0262 0.0266
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0799 0.9181 1
Onchocerca volvulus 0.0038 0.0262 0.0299
Echinococcus granulosus neuropeptide receptor 0.0038 0.0262 0.0266
Echinococcus granulosus thyroid hormone receptor alpha 0.0032 0.019 0.0192
Brugia malayi neuropeptide F receptor 0.0038 0.0262 0.0318
Schistosoma mansoni sodium / potassium ATPase beta chain 0.0468 0.53 0.6067
Echinococcus multilocularis nervana 2 0.0468 0.53 0.5299
Trypanosoma cruzi phosphomannose isomerase, putative 0.0094 0.0922 0.9816
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0534 0.0609
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0273 0.0276
Loa Loa (eye worm) hypothetical protein 0.0032 0.019 0.0216
Brugia malayi Pre-SET motif family protein 0.0061 0.0534 0.065
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0038 0.0262 0.0261
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0023 0.0091 0.0109
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Echinococcus multilocularis dro:myosuppressin receptor 0.0038 0.0262 0.0261
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0019 0.0018
Onchocerca volvulus Huntingtin homolog 0.0121 0.1235 0.1412
Schistosoma mansoni hypothetical protein 0.0038 0.0262 0.0299
Onchocerca volvulus 0.0035 0.0234 0.0266
Schistosoma mansoni patched 1 0.0045 0.0351 0.0401
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0094 0.0922 0.1123
Brugia malayi hypothetical protein 0.0032 0.019 0.023
Echinococcus multilocularis cation transporting atpase worm 0.0017 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0035 0.0234 0.0266
Brugia malayi Melatonin receptor type 1A 0.0038 0.0262 0.0318
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0067 0.0604 0.0602
Brugia malayi nuclear hormone receptor 0.0067 0.0604 0.0735
Onchocerca volvulus 0.0038 0.0262 0.0299
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0032 0.019 0.0189
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Onchocerca volvulus 0.0038 0.0262 0.0299
Loa Loa (eye worm) hypothetical protein 0.0035 0.0234 0.0266
Onchocerca volvulus 0.0038 0.0262 0.0299
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0035 0.0234 0.0267
Echinococcus granulosus single minded 2 0.0074 0.0688 0.07
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0507 0.0515
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0025 0.0118 0.0133
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0067 0.0604 0.069
Brugia malayi sulfakinin receptor protein 0.0038 0.0262 0.0318
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0032 0.019 0.0216
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0262 0.0266
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0234 0.0237
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0126 0.02
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0234 0.0237
Brugia malayi bZIP transcription factor family protein 0.0083 0.079 0.0962
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0019 0.0021
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0066 0.0598 0.0683
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0126 0.1185
Entamoeba histolytica hypothetical protein 0.0039 0.0273 0.2464
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0262 0.0299
Echinococcus granulosus 7TM GPCR rhodopsin 0.0038 0.0262 0.0266
Schistosoma mansoni opsin-like receptor 0.0038 0.0262 0.0299
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0067 0.0604 0.0613
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Loa Loa (eye worm) hypothetical protein 0.0017 0.0016 0.0017
Echinococcus multilocularis neuropeptide receptor A26 0.0038 0.0262 0.0261
Echinococcus granulosus nervana 2 0.0761 0.8734 0.8897
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0038 0.0262 0.0318
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0262 0.0299
Echinococcus granulosus geminin 0.0348 0.3903 0.3975
Schistosoma mansoni amine GPCR 0.0038 0.0262 0.0299
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.0351 0.035
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Loa Loa (eye worm) E1-E2 ATPase 0.0034 0.0215 0.0244
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0534 0.0609
Brugia malayi orphan nuclear receptor NR2E1 0.0032 0.019 0.023
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0017 0.0016 0.0015
Onchocerca volvulus 0.0035 0.0234 0.0266
Echinococcus granulosus nervana 2 0.0761 0.8734 0.8897
Loa Loa (eye worm) hypothetical protein 0.0329 0.3675 0.4206
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0262 0.0261
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0042 0.0316 0.3251
Loa Loa (eye worm) hypothetical protein 0.0055 0.0471 0.0537
Mycobacterium ulcerans beta-lactamase 0.0035 0.0234 0.0237
Echinococcus multilocularis transfer RNA-Lys 0.0074 0.0688 0.0687
Brugia malayi GnHR receptor homolog 0.0038 0.0262 0.0318
Echinococcus granulosus tachykinin peptides receptor 99D 0.0038 0.0262 0.0266
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0017 0.0016 0.0018
Echinococcus multilocularis copper transporting ATPase 1 0.0017 0.0016 0.0015
Schistosoma mansoni neuropeptide receptor 0.0038 0.0262 0.0299
Plasmodium falciparum calcium-transporting ATPase 0.0042 0.0316 0.3311
Leishmania major P-type H -ATPase, putative 0.0034 0.0215 0.0926
Schistosoma mansoni hypothetical protein 0.0348 0.3903 0.4468
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0038 0.0262 0.0266
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0042 0.0316 0.3251
Brugia malayi nuclear receptor RXR 0.0032 0.019 0.023
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0067 0.0604 0.0735
Echinococcus granulosus jun protein 0.0083 0.079 0.0803
Schistosoma mansoni nuclear hormone receptor 0.0032 0.019 0.0216
Brugia malayi Niemann-Pick C1 protein precursor 0.0105 0.1057 0.1288
Brugia malayi hypothetical protein 0.0038 0.0262 0.0318
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0025 0.0118 0.0142
Onchocerca volvulus 0.0035 0.0234 0.0266
Brugia malayi hypothetical protein 0.0017 0.0025 0.0029
Brugia malayi putative neuropeptide receptor 0.0038 0.0262 0.0318
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0067 0.0604 0.069
Loa Loa (eye worm) hypothetical protein 0.0329 0.3675 0.4206
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0262 0.0299
Onchocerca volvulus 0.0038 0.0262 0.0299
Brugia malayi hypothetical protein 0.0065 0.0582 0.0708
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.003 0.017 0.1473
Brugia malayi hypothetical protein 0.0038 0.0262 0.0318
Schistosoma mansoni hypothetical protein 0.0044 0.0332 0.0379
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0146 0.1529 0.1864
Echinococcus granulosus gamma secretase subunit aph 1 0.0245 0.2689 0.2739
Echinococcus granulosus g protein coupled receptor 0.0038 0.0262 0.0266
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0053 0.044 0.4069
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0042 0.0316 0.0321
Leishmania major P-type H -ATPase, putative 0.0034 0.0215 0.0926
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0351 0.0614
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.003 0.017 0.1473
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Onchocerca volvulus 0.0032 0.019 0.0216
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0038 0.0262 0.0299
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0017 0.0016 0.0018
Echinococcus multilocularis Niemann Pick C1 protein 0.0105 0.1057 0.1056
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0042 0.0316 0.036
Brugia malayi hypothetical protein 0.0038 0.0262 0.0318
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0042 0.0316 0.0384
Onchocerca volvulus 0.0468 0.53 0.6067
Plasmodium vivax calcium-transporting ATPase, putative 0.0053 0.044 0.4758
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0262 0.0266
Onchocerca volvulus Bile acid receptor homolog 0.0067 0.0604 0.069
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0019 0.0015
Echinococcus granulosus nervana 2 0.0468 0.53 0.5398
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0067 0.0604 0.069
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0019 0.0018
Plasmodium falciparum flap endonuclease 1 0.0028 0.0148 0.1454
Schistosoma mansoni histamine h1 receptor 0.0038 0.0262 0.0299
Brugia malayi Dopamine receptor protein 2 0.0038 0.0262 0.0318
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0038 0.0262 0.0299
Brugia malayi hypothetical protein 0.0027 0.0137 0.0166
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0053 0.044 0.477
Schistosoma mansoni growth hormone secretagogue receptor 0.0038 0.0262 0.0299
Brugia malayi intermediate filament protein 0.0055 0.0471 0.0573
Schistosoma mansoni cation-transporting atpase worm 0.0017 0.0016 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0534 0.0609
Trypanosoma cruzi P-type H+-ATPase, putative 0.0034 0.0215 0.2151
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0042 0.0316 0.0315
Brugia malayi RE15519p 0.0038 0.0262 0.0318
Brugia malayi ORL1-like opioid receptor 0.0038 0.0262 0.0318
Mycobacterium leprae probable mannose-6-phosphate isomerase ManA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHO 0.0051 0.0418 0.0438
Echinococcus multilocularis FTZ F1 alpha 0.0067 0.0604 0.0602
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0035 0.0234 0.0267
Loa Loa (eye worm) hypothetical protein 0.0026 0.0126 0.0142
Echinococcus granulosus cation transporting atpase worm 0.0017 0.0016 0.0015
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0023 0.0091 0.0989
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0234 0.1031
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0534 0.0609
Loa Loa (eye worm) hypothetical protein 0.0035 0.0234 0.0267
Echinococcus granulosus Niemann Pick C1 protein 0.0151 0.1587 0.1616
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Brugia malayi nuclear hormone receptor family member nhr-6 0.0032 0.019 0.023
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0042 0.0316 0.036
Toxoplasma gondii ABC1 family protein 0.0035 0.0234 0.2537
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0032 0.019 0.0192
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0053 0.044 0.2005
Brugia malayi beta-lactamase family protein 0.0035 0.0234 0.0284
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0032 0.019 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0067 0.0604 0.0735
Loa Loa (eye worm) hypothetical protein 0.0761 0.8734 1
Brugia malayi hypothetical protein 0.0038 0.0262 0.0318
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0021
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0468 0.53 0.5299
Echinococcus multilocularis Ankyrin 0.0016 0.0003 0.0002
Echinococcus granulosus alpha 1A adrenergic receptor 0.0038 0.0262 0.0266
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0534 0.0532
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0019 0.0187
Brugia malayi Ets-domain containing protein 0.0078 0.073 0.0889
Schistosoma mansoni gamma-secretase subunit aph-1 0.0245 0.2689 0.3078
Mycobacterium tuberculosis Conserved protein 0.0035 0.0234 0.0237
Echinococcus granulosus aryl hydrocarbon receptor 0.0026 0.0126 0.0126
Brugia malayi putative neuropeptide receptor NPR1 0.0038 0.0262 0.0318
Echinococcus granulosus somatostatin receptor 0.0038 0.0262 0.0266
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0262 0.0261
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.002
Brugia malayi hypothetical protein 0.0121 0.1235 0.1505
Brugia malayi Membrane calcium atpase protein 3 0.0042 0.0316 0.0384
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0262 0.0261
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0019 0.0003
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0761 0.8734 0.8897
Schistosoma mansoni myosin xvIII 0.0038 0.0262 0.0299
Onchocerca volvulus 0.0761 0.8734 1
Echinococcus granulosus FTZ F1 alpha 0.0067 0.0604 0.0613
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0262 0.0261
Loa Loa (eye worm) hypothetical protein 0.0093 0.0906 0.1036
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0234 0.0399
Echinococcus granulosus Nuclear hormone receptor HR96 0.0032 0.019 0.0192
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0067 0.0604 0.069
Echinococcus multilocularis g-protein coupled receptor 0.0038 0.0262 0.0261
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0234 0.0399
Echinococcus granulosus bloom syndrome protein 0.0023 0.0089 0.0089
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0067 0.0604 0.0613
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0053 0.044 0.1977
Onchocerca volvulus 0.0032 0.019 0.0216
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0262 0.0261
Loa Loa (eye worm) hypothetical protein 0.0032 0.019 0.0216
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0035 0.0234 0.0237
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0019 0.0022
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0442 0.0504
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Loa Loa (eye worm) hypothetical protein 0.0027 0.0135 0.0152
Echinococcus granulosus nuclear receptor nhr 48 0.0032 0.019 0.0192
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0019 0.002
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0126 0.1185
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0262 0.0299
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0042 0.0316 0.036
Brugia malayi Pax transcription factor protein 2 0.0258 0.2842 0.3467
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0262 0.0299
Echinococcus multilocularis nervana 2 0.0761 0.8734 0.8734
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Brugia malayi Flap endonuclease-1 0.0028 0.0148 0.0179
Leishmania major hypothetical protein, conserved 0.0027 0.0137 0.0566
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0262 0.0266
Loa Loa (eye worm) hypothetical protein 0.0095 0.0936 0.107
Onchocerca volvulus 0.0038 0.0262 0.0299
Schistosoma mansoni ATPase 0.0053 0.044 0.0502
Trypanosoma brucei pteridine reductase 1 0.0197 0.2127 1
Schistosoma mansoni adenoreceptor 0.0038 0.0262 0.0299
Schistosoma mansoni hypothetical protein 0.0348 0.3903 0.4468
Mycobacterium leprae Probable lipase LipE 0.0035 0.0234 0.0237
Schistosoma mansoni thyroid hormone receptor 0.0067 0.0604 0.069
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0262 0.0266
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0067 0.0604 0.0613
Echinococcus multilocularis cation transporting ATPase 13A3 0.0017 0.0016 0.0015
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.002
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0038 0.0262 0.0266
Echinococcus granulosus expressed conserved protein 0.0099 0.0982 0.0999
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0262 0.0299
Onchocerca volvulus Huntingtin homolog 0.0121 0.1235 0.1412
Schistosoma mansoni coup transcription factor 0.0067 0.0604 0.069
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0038 0.0262 0.0261
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0234 0.0237
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0053 0.044 0.1977
Schistosoma mansoni nuclear receptor nhr-48 0.0032 0.019 0.0216
Onchocerca volvulus 0.0146 0.1529 0.1749
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0107 0.1076 0.123
Trypanosoma brucei P-type H+-ATPase, putative 0.0034 0.0215 0.094
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0017 0.0016 0.0017
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0234 0.0266
Schistosoma mansoni amine GPCR 0.0038 0.0262 0.0299
Schistosoma mansoni hypothetical protein 0.0039 0.0273 0.031
Onchocerca volvulus 0.0258 0.2842 0.3253
Brugia malayi Pre-SET motif family protein 0.0424 0.4789 0.5844
Loa Loa (eye worm) hypothetical protein 0.0026 0.0123 0.0139
Leishmania major protein kinase, putative 0.0026 0.0126 0.051
Echinococcus granulosus biogenic amine 5HT receptor 0.0158 0.1667 0.1697
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0042 0.0316 0.036
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0234 0.0284
Loa Loa (eye worm) hypothetical protein 0.0025 0.0118 0.0133
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0042 0.0316 0.343
Loa Loa (eye worm) hypothetical protein 0.0761 0.8734 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0262 0.0261
Loa Loa (eye worm) nuclear hormone receptor 0.0032 0.019 0.0216
Echinococcus multilocularis orexin receptor type 2 0.0038 0.0262 0.0261
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0262 0.0266
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0262 0.0299
Leishmania major calcium motive p-type ATPase, putative 0.0042 0.0316 0.14
Echinococcus granulosus 7tm_1 domain containing protein 0.0038 0.0262 0.0266
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Echinococcus granulosus g protein coupled receptor 0.0038 0.0262 0.0266
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0262 0.0261
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0019 0.021
Schistosoma mansoni survival motor neuron protein 0.0146 0.1529 0.1749
Schistosoma mansoni retinoic acid receptor RXR 0.0067 0.0604 0.069
Echinococcus granulosus tm gpcr rhodopsin 0.0853 0.9817 1
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0026 0.0126 0.02
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0067 0.0604 0.069
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0137 0.0574
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0234 0.0284
Schistosoma mansoni aryl hydrocarbon receptor 0.01 0.0993 0.1135
Echinococcus granulosus hypothetical protein 0.0717 0.8224 0.8378
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0234 0.0237
Brugia malayi G-protein coupled receptor 0.0038 0.0262 0.0318
Trichomonas vaginalis cation-transporting ATPase, putative 0.0053 0.044 0.0775
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0262 0.0261
Brugia malayi gamma-secretase subunit aph-1 0.0245 0.2689 0.3281
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0089 0.0133
Brugia malayi nuclear hormone receptor 0.0032 0.019 0.023
Trypanosoma brucei calcium-translocating P-type ATPase 0.0042 0.0316 0.142
Echinococcus granulosus fmrfamide receptor 0.0038 0.0262 0.0266
Schistosoma mansoni hypothetical protein 0.0038 0.0262 0.0299
Loa Loa (eye worm) hypothetical protein 0.0032 0.019 0.0216
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.0032 0.019 0.0216
Schistosoma mansoni neuropeptide f receptor 76f 0.0038 0.0262 0.0299
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0038 0.0262 0.0318
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0126 0.02
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0126 0.1185
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0053 0.044 0.0438
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0026 0.0126 0.0126
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0067 0.0604 0.0735
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0137 0.1471
Loa Loa (eye worm) beta-lactamase 0.0035 0.0234 0.0266
Onchocerca volvulus 0.0038 0.0262 0.0299
Schistosoma mansoni nuclear receptor 0.0032 0.019 0.0216
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0262 0.0266
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0038 0.0262 0.0261
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0112 0.1131 0.1379
Brugia malayi hypothetical protein 0.0038 0.0262 0.0318
Entamoeba histolytica hypothetical protein 0.0039 0.0273 0.2464
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0245 0.2689 0.3078
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0262 0.0261
Entamoeba histolytica phosphomannose isomerase, putative 0.0094 0.0922 0.8702
Loa Loa (eye worm) hypothetical protein 0.0035 0.0234 0.0267
Schistosoma mansoni steroid hormone receptor ad4bp 0.0067 0.0604 0.069
Echinococcus granulosus microtubule associated protein 2 0.069 0.7907 0.8055
Onchocerca volvulus 0.0055 0.0471 0.0537
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Echinococcus multilocularis lamin 0.0055 0.0471 0.0469
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0019 0.0015
Echinococcus multilocularis thyroid hormone receptor alpha 0.0067 0.0604 0.0602
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0067 0.0604 0.0602
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0038 0.0262 0.0299
Echinococcus granulosus nervana 2 0.0468 0.53 0.5398
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0234 0.0237
Schistosoma mansoni biogenic amine receptor 0.0038 0.0262 0.0299
Echinococcus granulosus Niemann Pick C1 protein 0.0105 0.1057 0.1075
Loa Loa (eye worm) hypothetical protein 0.0032 0.019 0.0216
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0094 0.0922 0.1123
Brugia malayi tailless protein 0.0032 0.019 0.023
Loa Loa (eye worm) hypothetical protein 0.0061 0.0534 0.0609
Loa Loa (eye worm) hypothetical protein 0.0053 0.0447 0.051
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0067 0.0604 0.069
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0032 0.019 0.0216
Trichomonas vaginalis cation-transporting ATPase, putative 0.0053 0.044 0.0775
Loa Loa (eye worm) hypothetical protein 0.0032 0.019 0.0216
Loa Loa (eye worm) hypothetical protein 0.0053 0.044 0.0502
Brugia malayi Dopamine receptor protein 1 0.0038 0.0262 0.0318
Onchocerca volvulus 0.0061 0.0534 0.0609
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0053 0.044 0.3558
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.019 0.0192
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0105 0.1057 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0853 0.9817 0.9817
Brugia malayi ecdysteroid receptor 0.0067 0.0604 0.0735
Onchocerca volvulus 0.0065 0.0582 0.0665
Schistosoma mansoni hypothetical protein 0.0051 0.0418 0.0477
Schistosoma mansoni alpha-1 adrenergic receptor 0.0038 0.0262 0.0299
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0038 0.0262 0.0299
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0447 0.051
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0234 0.0266
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0118 0.1206 1
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0148 0.0624
Trichomonas vaginalis esterase, putative 0.0035 0.0234 0.0399
Schistosoma mansoni single-minded 0.01 0.0993 0.1135
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0038 0.0262 0.0261
Trichomonas vaginalis adenylate cyclase, putative 0.0026 0.0126 0.02
Brugia malayi Serotonin receptor 0.0491 0.557 0.6797
Loa Loa (eye worm) RecQ helicase 0.0023 0.0089 0.01
Schistosoma mansoni hypothetical protein 0.0044 0.0332 0.0379
Brugia malayi nuclear receptor RXR 0.0035 0.0234 0.0284
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0126 0.02
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0019 0.0018
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0067 0.0604 0.0602
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0262 0.0261
Echinococcus multilocularis nuclear receptor nhr 48 0.0032 0.019 0.0189
Loa Loa (eye worm) hypothetical protein 0.0129 0.133 0.1521
Loa Loa (eye worm) calcium ATPase 0.003 0.017 0.0192
Echinococcus granulosus Ankyrin 0.0016 0.0003 0.0002
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0234 0.0237
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0148 0.0146
Loa Loa (eye worm) hypothetical protein 0.0032 0.019 0.0216
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0262 0.0261
Mycobacterium ulcerans putative regulatory protein 0.0074 0.0688 0.0733
Brugia malayi beta-lactamase family protein 0.0035 0.0234 0.0284
Brugia malayi Fli-1 protein 0.0236 0.2581 0.3148
Brugia malayi Nuclear hormone receptor E75 0.0032 0.019 0.023
Loa Loa (eye worm) hypothetical protein 0.0076 0.0711 0.0812
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0761 0.8734 0.8897
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0234 0.0237
Echinococcus multilocularis G protein coupled receptor 139 0.0038 0.0262 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0126 0.02
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.000000072537
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0026 0.0126 0.02
Schistosoma mansoni gabp alpha 0.0078 0.073 0.0834
Echinococcus granulosus survival motor neuron protein 1 0.0715 0.8195 0.8347
Schistosoma mansoni amine GPCR 0.0038 0.0262 0.0299
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0038 0.0262 0.0299
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0067 0.0604 0.0735
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0169 0.0192
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0148 0.1585
Onchocerca volvulus 0.0026 0.0126 0.0142
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0761 0.8734 0.8734
Schistosoma mansoni ets-related 0.0236 0.2581 0.2954
Echinococcus granulosus tumor protein p63 0.0362 0.4063 0.4138
Schistosoma mansoni nuclear hormone receptor 0.0032 0.019 0.0216
Echinococcus multilocularis nervana 2 0.0761 0.8734 0.8734
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0067 0.0604 0.069
Echinococcus granulosus sex peptide receptor 0.0038 0.0262 0.0266
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0053 0.044 0.0775
Echinococcus multilocularis ecdysone induced protein 78C 0.0067 0.0604 0.0602
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Loa Loa (eye worm) TYRA-2 protein 0.0038 0.0262 0.0299
Schistosoma mansoni hypothetical protein 0.0067 0.0608 0.0695
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0262 0.0299
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0148 0.1106
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0067 0.0604 0.0735
Mycobacterium ulcerans proteasome PrcA 0.0799 0.9181 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.0351 0.0356
Onchocerca volvulus 0.0038 0.0262 0.0299
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0262 0.0266
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0129 0.133 0.1521
Echinococcus granulosus copper transporting ATPase 1 0.0017 0.0016 0.0015
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0262 0.0266
Schistosoma mansoni amine GPCR 0.0038 0.0262 0.0299
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0262 0.0261
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0067 0.0604 0.069
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0126 0.1185
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0019 0.0046 0.0322
Trypanosoma brucei Aph-1 protein, putative 0.0095 0.0939 0.4369
Trypanosoma brucei P-type H+-ATPase, putative 0.0034 0.0215 0.094
Loa Loa (eye worm) hypothetical protein 0.0018 0.0035 0.0038
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0001 0.000000068054
Schistosoma mansoni biogenic amine (5HT) receptor 0.0158 0.1667 0.1908
Loa Loa (eye worm) hypothetical protein 0.0158 0.1667 0.1908
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0329 0.3675 0.4483
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0471 0.0573
Onchocerca volvulus Neuropeptide F receptor homolog 0.0038 0.0262 0.0299
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0053 0.044 0.0438
Mycobacterium tuberculosis Probable mannose-6-phosphate isomerase ManA (phosphomannose isomerase) (phosphomannoisomerase) (PMI) (phosphohexoisomerase) (pho 0.0051 0.0418 0.0438
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0042 0.0316 0.142
Echinococcus granulosus peptide allatostatin:somatostatin 0.0038 0.0262 0.0266
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0262 0.0266
Trypanosoma cruzi Aph-1 protein, putative 0.0095 0.0939 1
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0126 0.02
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0262 0.0266
Schistosoma mansoni lamin 0.0055 0.0471 0.0537
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0038 0.0262 0.0299
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0262 0.0261
Loa Loa (eye worm) hypothetical protein 0.0055 0.0471 0.0537
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0129 0.133 0.1521
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0019 0.0034
Loa Loa (eye worm) pax transcription factor protein 2 0.0258 0.2842 0.3253
Loa Loa (eye worm) hypothetical protein 0.0428 0.4835 0.5535
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0273 0.0271
Mycobacterium leprae Possible regulatory protein 0.0026 0.0126 0.0119
Brugia malayi Nuclear hormone receptor E75 0.0032 0.019 0.023
Loa Loa (eye worm) hypothetical protein 0.0158 0.1667 0.1908
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0471 0.0537
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0089 0.0107
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0019 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0234 0.2359
Loa Loa (eye worm) hypothetical protein 0.0067 0.0604 0.069
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0148 0.0241
Schistosoma mansoni hypothetical protein 0.0146 0.1529 0.1749
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0053 0.044 0.0775
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0067 0.0604 0.0735
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0262 0.0266
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0262 0.0261
Echinococcus multilocularis somatostatin receptor 0.0038 0.0262 0.0261
Brugia malayi hypothetical protein 0.0038 0.0262 0.0318
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0447 0.0544
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0129 0.133 0.1433
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0067 0.0604 0.0602
Schistosoma mansoni zinc finger protein 0.0032 0.019 0.0216
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0262 0.0261
Brugia malayi Serotonin receptor 0.0038 0.0262 0.0318
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0262 0.0266
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0067 0.0604 0.069
Loa Loa (eye worm) hypothetical protein 0.008 0.0763 0.0872
Echinococcus multilocularis Niemann Pick C1 protein 0.0151 0.1587 0.1586
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0035 0.0234 0.0233
Onchocerca volvulus 0.0038 0.0262 0.0299
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0262 0.0299
Echinococcus multilocularis cation transporting ATPase 13A1 0.0017 0.0016 0.0015
Leishmania major pteridine reductase 1 0.0199 0.2158 1
Brugia malayi hypoxia-induced factor 1 0.031 0.3448 0.4207
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0053 0.044 0.477
Plasmodium vivax cation transporting ATPase, putative 0.0017 0.0016 0.0154
Brugia malayi AKH receptor 0.0038 0.0262 0.0318
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0053 0.044 0.0462
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0761 0.8734 1
Brugia malayi MH2 domain containing protein 0.0128 0.132 0.1609
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Plasmodium vivax mannose-6-phosphate isomerase, putative 0.0094 0.0922 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0234 0.0266
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0036 0.0241 0.0245
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0273 0.031
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0038 0.0262 0.0261
Schistosoma mansoni lozenge 0.0054 0.045 0.0514
Brugia malayi hypothetical protein 0.013 0.1349 0.1645
Brugia malayi Uncoordinated protein 44 0.0015 0.0001 0.000000072537
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0023 0.0091 0.0103
Loa Loa (eye worm) hypothetical protein 0.0067 0.0604 0.069
Schistosoma mansoni transmemberane protein 0.0761 0.8734 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0038 0.0262 0.0261
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0471 0.0537
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0249 0.0302
Loa Loa (eye worm) hypothetical protein 0.0037 0.0249 0.0283
Loa Loa (eye worm) hypothetical protein 0.0027 0.0137 0.0156
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0083 0.079 0.0789
Schistosoma mansoni amine GPCR 0.0364 0.4084 0.4675
Loa Loa (eye worm) hypothetical protein 0.0053 0.0442 0.0504
Onchocerca volvulus 0.0074 0.0688 0.0787
Brugia malayi Nuclear hormone receptor-like 1 0.0035 0.0234 0.0284
Loa Loa (eye worm) hypothetical protein 0.0067 0.0604 0.069
Plasmodium vivax copper-transporting ATPase, putative 0.0017 0.0016 0.0154
Echinococcus multilocularis GA binding protein alpha chain 0.0078 0.073 0.0729
Schistosoma mansoni biogenic amine receptor 0.0038 0.0262 0.0299
Echinococcus multilocularis serotonin receptor 0.0158 0.1667 0.1666
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0234 0.0237
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0056 0.0443
Brugia malayi CHE-14 protein 0.0045 0.0351 0.0427
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0262 0.0299
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0067 0.0604 0.0602
Loa Loa (eye worm) fli-1 protein 0.0236 0.2581 0.2954
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0262 0.0266
Brugia malayi hypothetical protein 0.0038 0.0262 0.0318
Onchocerca volvulus 0.0038 0.0262 0.0299
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0126 0.051
Schistosoma mansoni thyroid hormone receptor 0.0067 0.0604 0.069
Echinococcus multilocularis survival motor neuron protein 1 0.0715 0.8195 0.8194
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0017 0.0016 0.0177
Loa Loa (eye worm) hypothetical protein 0.0035 0.0234 0.0267
Loa Loa (eye worm) hypothetical protein 0.0035 0.0234 0.0266
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0126 0.02
Schistosoma mansoni hypothetical protein 0.0044 0.0332 0.0379
Leishmania major hypothetical protein, conserved 0.0035 0.0234 0.1016
Onchocerca volvulus 0.0428 0.4835 0.5535
Loa Loa (eye worm) hypothetical protein 0.0105 0.1057 0.1209
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0137 0.1338
Echinococcus granulosus lamin 0.0055 0.0471 0.0478
Loa Loa (eye worm) hypothetical protein 0.0038 0.0262 0.0299
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0067 0.0604 0.0735
Brugia malayi Death domain containing protein 0.0015 0.0001 0.000000072537
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0038 0.0262 0.0299
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0067 0.0604 0.0613

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 0 % Evaluation for percent inhibition of prostaglandin G/H synthase 2 in human whole blood (HWB) at a concentration of 1 um ChEMBL. 15084117
Inhibition (binding) = 0 % Evaluation for percent inhibition of prostaglandin G/H synthase 2 in human whole blood (HWB) at a concentration of 1 um ChEMBL. 15084117
Inhibition (binding) = 25 % Percentage inhibition of prostaglandin G/H synthase 1 in human whole blood (HWB) at a concentration of 100 um ChEMBL. 15084117
Inhibition (binding) = 25 % Percentage inhibition of prostaglandin G/H synthase 1 in human whole blood (HWB) at a concentration of 100 um ChEMBL. 15084117
Inhibition (binding) = 30 % Evaluation for percent inhibition of prostaglandin G/H synthase 2 in human whole blood (HWB) at a concentration of 10 um ChEMBL. 15084117
Inhibition (binding) = 30 % Evaluation for percent inhibition of prostaglandin G/H synthase 2 in human whole blood (HWB) at a concentration of 1 um ChEMBL. 15084117
Inhibition (binding) = 30 % Evaluation for percent inhibition of prostaglandin G/H synthase 2 in human whole blood (HWB) at a concentration of 10 um ChEMBL. 15084117
Inhibition (binding) = 60 % Percentage inhibition of prostaglandin G/H synthase 1 in human whole blood (HWB) at a concentration of 100 um ChEMBL. 15084117
Inhibition (binding) = 90 % Evaluation for percent inhibition of prostaglandin G/H synthase 2 in human whole blood (HWB) at a concentration of 10 um ChEMBL. 15084117

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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