Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0138 | 0.8299 | 0.8299 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.1278 | 0.1278 |
Echinococcus granulosus | acetylcholinesterase | 0.0138 | 0.8299 | 0.8122 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0138 | 0.8299 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0945 | 0.0945 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0945 | 0.1139 |
Echinococcus granulosus | carboxylesterase 5A | 0.0138 | 0.8299 | 0.8122 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0945 | 0.1139 |
Loa Loa (eye worm) | RNA binding protein | 0.0067 | 0.265 | 0.265 |
Echinococcus multilocularis | acetylcholinesterase | 0.0138 | 0.8299 | 0.8122 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.8299 | 0.8299 |
Echinococcus granulosus | muscleblind protein | 0.0159 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0138 | 0.8299 | 0.8122 |
Loa Loa (eye worm) | carboxylesterase | 0.0138 | 0.8299 | 0.8299 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0945 | 0.0945 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.1278 | 0.1278 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0159 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0067 | 0.265 | 0.265 |
Echinococcus granulosus | tar DNA binding protein | 0.0067 | 0.265 | 0.1883 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.265 | 0.3194 |
Echinococcus multilocularis | muscleblind protein | 0.0159 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0945 | 0.1139 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.8299 | 0.8299 |
Brugia malayi | RNA binding protein | 0.0067 | 0.265 | 0.265 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1278 | 0.1278 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.265 | 0.3194 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0138 | 0.8299 | 0.8122 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.265 | 0.3194 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0067 | 0.265 | 0.265 |
Loa Loa (eye worm) | TAR-binding protein | 0.0067 | 0.265 | 0.265 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.265 | 0.3194 |
Brugia malayi | Carboxylesterase family protein | 0.0138 | 0.8299 | 0.8299 |
Brugia malayi | TAR-binding protein | 0.0067 | 0.265 | 0.265 |
Echinococcus multilocularis | acetylcholinesterase | 0.0138 | 0.8299 | 0.8122 |
Brugia malayi | Carboxylesterase family protein | 0.0138 | 0.8299 | 0.8299 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 0.265 | 0.3194 |
Echinococcus multilocularis | tar DNA binding protein | 0.0067 | 0.265 | 0.1883 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.1278 | 0.1278 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.