Detailed information for compound 1153741

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 605.958 | Formula: C36H69N4O3+
  • H donors: 4 H acceptors: 2 LogP: 6.75 Rotable bonds: 18
    Rule of 5 violations (Lipinski): 2
  • SMILES: O[C@@H]1CC[C@]2([C@H](C1)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2[C@@H](COC(=O)NCCCNCCCCNCCC[N+](C)(C)C)C)C)C
  • InChi: 1S/C36H68N4O3/c1-27(26-43-34(42)39-23-9-21-37-19-7-8-20-38-22-10-24-40(4,5)6)31-13-14-32-30-12-11-28-25-29(41)15-17-35(28,2)33(30)16-18-36(31,32)3/h27-33,37-38,41H,7-26H2,1-6H3/p+1/t27-,28+,29-,30+,31-,32+,33+,35+,36-/m1/s1
  • InChiKey: TUEDLLSKYISCES-ICLXHHOBSA-O  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi SRC-1 0.0023 0.0021 0.0021
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0064 0.0066
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Echinococcus granulosus geminin 0.0192 0.0435 0.0434
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0064 0.0063
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0085 0.0172 0.0377
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Schistosoma mansoni cpg binding protein 0.0033 0.0044 0.0043
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0061 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0054 0.0095 0.0099
Echinococcus granulosus tyrosine protein kinase ABL1 0.0023 0.0021 0.002
Trypanosoma cruzi cyclin, putative 0.0092 0.019 0.0223
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Trypanosoma brucei dihydrolipoamide acetyltransferase E2 subunit, putative 0.0143 0.0315 0.0314
Schistosoma mansoni lamin 0.0028 0.0032 0.0031
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Echinococcus granulosus mitogen activated protein kinase 15 0.0052 0.0092 0.0091
Giardia lamblia Kinase, NEK 0.0023 0.0021 0.0119
Echinococcus multilocularis integrin linked protein kinase 0.0023 0.0021 0.002
Trypanosoma cruzi trypanothione reductase, putative 0.0039 0.0059 0.0069
Trichomonas vaginalis esterase, putative 0.0041 0.0064 0.0632
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0055 0.0546
Schistosoma mansoni microtubule-associated protein tau 0.0751 0.1807 0.1806
Brugia malayi Cyclin, N-terminal domain containing protein 0.0015 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Echinococcus granulosus Immunoglobulin 0.0256 0.0593 0.0592
Toxoplasma gondii pyruvate carboxylase 0.1557 0.3786 0.3786
Entamoeba histolytica cyclin, putative 0.0092 0.019 0.1128
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0064 0.0063
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0023 0.0021 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Echinococcus multilocularis kinase suppressor of Ras 1 0.0023 0.0021 0.002
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0092 0.0913
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Loa Loa (eye worm) hypothetical protein 0.0017 0.0005 0.0005
Plasmodium falciparum dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 0.0143 0.0315 0.0371
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.0256 0.0593 0.0614
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Brugia malayi Cell division protein kinase 2 0.0052 0.0092 0.0095
Brugia malayi Raf kinase 0.0023 0.0021 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.1557 0.3786 0.3786
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0021 0.0021
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0064 0.0062
Loa Loa (eye worm) cyclin domain-containing protein 0.0015 0.0001 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Echinococcus multilocularis tyrosine protein kinase HCK 0.0023 0.0021 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0023 0.0021 0.02
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0023 0.0021 0.002
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Trypanosoma brucei protein kinase, putative 0.0052 0.0092 0.0091
Onchocerca volvulus 0.0041 0.0064 0.3121
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.4088 1 1
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0143 0.0315 0.0371
Mycobacterium tuberculosis Probable branched-chain keto acid dehydrogenase E2 component BkdC 0.0143 0.0315 0.0359
Schistosoma mansoni hypothetical protein 0.0192 0.0435 0.0434
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Brugia malayi Cyclin, N-terminal domain containing protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) TK protein kinase 0.0023 0.0021 0.0021
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0023 0.0021 0.002
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0023 0.0021 0.002
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.1557 0.3786 0.4469
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0113 0.0113
Trypanosoma brucei cdc2-related kinase 1 0.0061 0.0113 0.0113
Mycobacterium ulcerans acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 0.0554 0.1323 0.3472
Loa Loa (eye worm) TK/INSR protein kinase 0.0023 0.0021 0.0021
Schistosoma mansoni aspartate carbamoyltransferase 0.0352 0.0827 0.0827
Echinococcus granulosus cyclins 0.0063 0.0118 0.0117
Echinococcus multilocularis cyclins 0.0063 0.0118 0.0117
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0023 0.0021 0.002
Plasmodium falciparum carbamoyl phosphate synthetase 0.0352 0.0827 0.0976
Wolbachia endosymbiont of Brugia malayi isocitrate dehydrogenase 0.0421 0.0997 0.2282
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0085 0.0172 0.0172
Onchocerca volvulus 0.0023 0.0021 0.099
Loa Loa (eye worm) TK protein kinase 0.0023 0.0021 0.0021
Loa Loa (eye worm) TK/CSK protein kinase 0.0023 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0256 0.0593 0.0614
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Echinococcus granulosus tyrosine protein kinase Fyn 0.0023 0.0021 0.002
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0031 0.0023
Echinococcus multilocularis tyrosine protein kinase csk 0.0023 0.0021 0.002
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.3466 0.8473 0.8473
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0023 0.0021 0.002
Entamoeba histolytica serine/threonine kinase, putative 0.0023 0.0021 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0118 0.1174
Mycobacterium leprae Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB 0.0143 0.0315 0.0757
Echinococcus granulosus neuroglian 0.0256 0.0593 0.0592
Echinococcus granulosus tyrosine kinase 0.0023 0.0021 0.002
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0256 0.0593 0.0592
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0052 0.0092 0.0095
Onchocerca volvulus 0.0023 0.0021 0.099
Loa Loa (eye worm) hypothetical protein 0.0421 0.0997 0.1033
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0095 0.0099
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0055 0.0546
Trichomonas vaginalis cyclins, putative 0.0092 0.019 0.1896
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0031 0.0032
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Brugia malayi beta-lactamase family protein 0.0041 0.0064 0.0066
Plasmodium vivax thioredoxin reductase, putative 0.0039 0.0059 0.0069
Trypanosoma cruzi 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0143 0.0315 0.0371
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0092 0.0913
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Onchocerca volvulus 0.0033 0.0044 0.2157
Echinococcus granulosus serine:threonine protein kinase haspin 0.0042 0.0065 0.0065
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0021 0.002
Echinococcus granulosus Biotin lipoyl attachment 0.0143 0.0315 0.0314
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Loa Loa (eye worm) TK protein kinase 0.0023 0.0021 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Trichomonas vaginalis cyclins, putative 0.0092 0.019 0.1896
Echinococcus multilocularis lysosomal alpha glucosidase 0.0168 0.0376 0.0376
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0023 0.0021 0.002
Loa Loa (eye worm) protein kinase domain-containing protein 0.0023 0.0021 0.0021
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0023 0.0021 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Plasmodium falciparum thioredoxin reductase 0.0039 0.0059 0.0069
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0064 0.0632
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0014 0.0015
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0023 0.0021 0.0021
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0023 0.0021 0.002
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0023 0.0021 0.02
Schistosoma mansoni cyclins 0.0063 0.0118 0.0117
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Leishmania major dihydrolipoamide acetyltransferase precursorlike protein 0.0143 0.0315 0.0314
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Schistosoma mansoni protein kinase 0.0023 0.0021 0.002
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.0421 0.0997 0.1033
Loa Loa (eye worm) hypothetical protein 0.0037 0.0054 0.0055
Echinococcus granulosus lamin 0.0028 0.0032 0.0031
Echinococcus multilocularis hypothetical protein 0.0042 0.0065 0.0065
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0023 0.0021 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Schistosoma mansoni cell adhesion molecule 0.0256 0.0593 0.0592
Loa Loa (eye worm) TK protein kinase 0.0023 0.0021 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Brugia malayi Receptor family ligand binding region containing protein 0.0023 0.0021 0.0021
Loa Loa (eye worm) cyclin domain-containing protein 0.0015 0.0001 0.0001
Trichomonas vaginalis cyclins, putative 0.0044 0.0073 0.0722
Echinococcus granulosus cyclin B3 1 0.0063 0.0118 0.0117
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Echinococcus granulosus tyrosine protein kinase Lyn 0.0034 0.0047 0.0046
Trypanosoma cruzi cdc2-related kinase 3 0.0061 0.0113 0.0133
Mycobacterium tuberculosis Probable oxidoreductase 0.0099 0.0207 0.0231
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0005 0.0005
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0116 0.0116
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.0119
Echinococcus granulosus tyrosine protein kinase HCK 0.0023 0.0021 0.002
Toxoplasma gondii 2-oxo acid dehydrogenases acyltransferase (catalytic domain) domain-containing protein 0.0143 0.0315 0.0314
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0064 0.0074
Leishmania major 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative 0.0143 0.0315 0.0314
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0023 0.0021 0.002
Echinococcus multilocularis c src tyrosine kinase 0.0023 0.0021 0.002
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0023 0.0021 0.02
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0092 0.019 0.0189
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0117 0.0117
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0056 0.01 0.0185
Brugia malayi hypothetical protein 0.0042 0.0065 0.0068
Echinococcus multilocularis tyrosine protein kinase csk 0.0023 0.0021 0.002
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Loa Loa (eye worm) hypothetical protein 0.0143 0.0315 0.0326
Echinococcus granulosus GPCR family 2 0.0017 0.0005 0.0005
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0697 0.1675 1
Echinococcus multilocularis tyrosine protein kinase 0.0023 0.0021 0.002
Echinococcus granulosus tyrosine protein kinase Blk 0.0023 0.0021 0.002
Trypanosoma brucei protein kinase, putative 0.0034 0.0047 0.0046
Entamoeba histolytica serine/threonine kinase, putative 0.0023 0.0021 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Loa Loa (eye worm) hypothetical protein 0.0041 0.0064 0.0066
Loa Loa (eye worm) TK protein kinase 0.0023 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Giardia lamblia Kinase, NEK 0.0023 0.0021 0.0119
Loa Loa (eye worm) TK protein kinase 0.0023 0.0021 0.0021
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.0421 0.0997 0.0996
Echinococcus granulosus defective proboscis extension response 0.0256 0.0593 0.0592
Trichomonas vaginalis protein kinase atn1, putative 0.0023 0.0021 0.02
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Loa Loa (eye worm) TK/FAK protein kinase 0.0023 0.0021 0.0021
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.0119
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.0119
Onchocerca volvulus 0.0023 0.0021 0.099
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0256 0.0593 0.0592
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.3945 0.9648 1
Leishmania major trypanothione reductase 0.0039 0.0059 0.0059
Trypanosoma brucei Pseudokinase, putative 0.0023 0.0021 0.002
Schistosoma mansoni hypothetical protein 0.0042 0.0065 0.0065
Trichomonas vaginalis cyclin D, putative 0.0063 0.0118 0.1174
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Loa Loa (eye worm) TK/ROR protein kinase 0.0023 0.0021 0.0021
Trypanosoma brucei pyruvate dehydrogenase complex E3 binding protein, putative 0.0143 0.0315 0.0314
Giardia lamblia Cyclin A 0.0063 0.0118 0.0699
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.02
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0023 0.0021 0.002
Mycobacterium ulcerans dihydrolipoamide acetyltransferase 0.0143 0.0315 0.0799
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.1557 0.3786 0.3786
Mycobacterium ulcerans acetyl/propionyl CoA carboxylase subunit beta 0.0554 0.1323 0.3472
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.0119
Schistosoma mansoni hypothetical protein 0.0017 0.0005 0.0005
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0085 0.0172 0.0172
Trichomonas vaginalis AGC family protein kinase 0.0023 0.0021 0.02
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.1557 0.3786 0.3786
Brugia malayi SH2 domain containing protein 0.0023 0.0021 0.0021
Schistosoma mansoni cpg binding protein 0.0035 0.0049 0.0048
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0085 0.0172 0.0172
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Echinococcus granulosus lamin dm0 0.0028 0.0032 0.0031
Brugia malayi glutathione reductase 0.0039 0.0059 0.0061
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0023 0.0021 0.002
Echinococcus granulosus microtubule associated protein 2 0.0751 0.1807 0.1806
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0061 0.0113 0.0117
Loa Loa (eye worm) cyclin domain-containing protein 0.0015 0.0001 0.0001
Plasmodium falciparum protein kinase, putative 0.0023 0.0021 0.0024
Schistosoma mansoni pyruvate carboxylase 0.1557 0.3786 0.3786
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0031 0.003
Schistosoma mansoni acetyl-CoA carboxylase 0.4088 1 1
Chlamydia trachomatis dihydrolipoamide succinyltransferase 0.0143 0.0315 0.0881
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0052 0.0092 0.0107
Entamoeba histolytica ankyrin repeat protein 0.0023 0.0021 0.0119
Schistosoma mansoni hypothetical protein 0.0037 0.0054 0.0053
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Echinococcus granulosus cyclins 0.0063 0.0118 0.0117
Toxoplasma gondii STE kinase 0.0023 0.0021 0.002
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0089 0.0182 0.0202
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0023 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Brugia malayi beta-lactamase family protein 0.0041 0.0064 0.0066
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0034 0.0047 0.0046
Brugia malayi Cyclin, N-terminal domain containing protein 0.0015 0.0001 0.0001
Brugia malayi cell division control protein 2 homolog 0.0061 0.0113 0.0117
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Echinococcus granulosus kinase suppressor of Ras 1 0.0023 0.0021 0.002
Echinococcus granulosus activated cdc42 kinase 1 0.0023 0.0021 0.002
Echinococcus granulosus retinal guanylyl cyclase 2 0.0023 0.0021 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Brugia malayi Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta 0.0143 0.0315 0.0326
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.3466 0.8473 0.8473
Entamoeba histolytica serine/threonine kinase, putative 0.0023 0.0021 0.0119
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0054 0.0055
Giardia lamblia Kinase, CMGC CDK 0.0061 0.0113 0.0673
Leishmania major hypothetical protein, conserved 0.0023 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0256 0.0593 0.0614
Brugia malayi Tyrosine-protein kinase PR2 0.0023 0.0021 0.0021
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0005 0.0005
Treponema pallidum pyruvate carboxylase subunit B 0.0143 0.0315 1
Brugia malayi Thioredoxin reductase 0.0039 0.0059 0.0061
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0032 0.0033
Mycobacterium tuberculosis DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase 0.0143 0.0315 0.0359
Brugia malayi Cyclin C 0.0015 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Schistosoma mansoni hypothetical protein 0.0023 0.0021 0.002
Schistosoma mansoni protein kinase 0.0023 0.0021 0.002
Entamoeba histolytica cell division protein kinase 2, putative 0.0103 0.0215 0.1281
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Schistosoma mansoni serine/threonine RGC 0.0023 0.0021 0.002
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0089 0.0182 0.0403
Echinococcus granulosus fibroblast growth factor receptor 4 0.0023 0.0021 0.002
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0034 0.0047 0.0046
Echinococcus multilocularis protein tyrosine kinase 0.0023 0.0021 0.002
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0023 0.0021 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Schistosoma mansoni nephrin 0.0256 0.0593 0.0592
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.02
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0023 0.0021 0.0119
Echinococcus multilocularis tyrosine protein kinase pr2 0.0023 0.0021 0.002
Loa Loa (eye worm) TK protein kinase 0.0023 0.0021 0.0021
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0031 0.0045
Brugia malayi Cyclin, N-terminal domain containing protein 0.0063 0.0118 0.0122
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0099 0.0207 0.0231
Entamoeba histolytica ankyrin repeat protein 0.0023 0.0021 0.0119
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.0119
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0061 0.0113 0.0113
Echinococcus granulosus neuropeptide s receptor 0.0529 0.1263 0.1262
Onchocerca volvulus 0.0023 0.0021 0.099
Echinococcus multilocularis roundabout 2 0.0256 0.0593 0.0592
Trichomonas vaginalis protein tyrosine kinase, putative 0.0023 0.0021 0.02
Loa Loa (eye worm) cyclin C 0.0015 0.0001 0.0001
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.0554 0.1323 0.1323
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Entamoeba histolytica receptor protein kinase, putative 0.0023 0.0021 0.0119
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Echinococcus granulosus raf serine:threonine protein kinase 0.0023 0.0021 0.002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.3466 0.8473 0.8473
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0034 0.0047 0.0046
Chlamydia trachomatis dihydrolipoamide succinyltransferase 0.0143 0.0315 0.0881
Entamoeba histolytica serine/threonine kinase, putative 0.0023 0.0021 0.0119
Plasmodium vivax lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, putative 0.0143 0.0315 0.0371
Echinococcus granulosus epidermal growth factor receptor 0.0023 0.0021 0.002
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.1557 0.3786 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.019 0.0196
Mycobacterium tuberculosis Conserved protein 0.0041 0.0064 0.0062
Onchocerca volvulus 0.0023 0.0021 0.099
Schistosoma mansoni isocitrate dehydrogenase 0.0421 0.0997 0.0996
Schistosoma mansoni dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase 0.0143 0.0315 0.0314
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Entamoeba histolytica tyrosin kinase, putative 0.0023 0.0021 0.0119
Leishmania major isocitrate dehydrogenase, putative 0.0421 0.0997 0.0996
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Onchocerca volvulus 0.0023 0.0021 0.099
Echinococcus granulosus tyrosine protein kinase shark 0.0023 0.0021 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.02
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Brugia malayi Carboxyl transferase domain containing protein 0.3945 0.9648 1
Echinococcus multilocularis epidermal growth factor receptor 0.0023 0.0021 0.002
Plasmodium falciparum protein kinase, putative 0.0023 0.0021 0.0024
Onchocerca volvulus Tyrosine kinase homolog 0.0023 0.0021 0.099
Echinococcus multilocularis cyclin dependent kinase 9 0.0247 0.0571 0.057
Loa Loa (eye worm) hypothetical protein 0.0256 0.0593 0.0614
Trichomonas vaginalis G protein-coupled receptor kinase, putative 0.0052 0.0092 0.0913
Loa Loa (eye worm) hypothetical protein 0.0143 0.0315 0.0326
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0064 0.0632
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.0421 0.0997 0.1033
Mycobacterium leprae Probable lipase LipE 0.0041 0.0064 0.0088
Echinococcus granulosus cyclin b3 0.0063 0.0118 0.0117
Echinococcus multilocularis neuropeptide s receptor 0.0529 0.1263 0.1262
Brugia malayi Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial precursor 0.0143 0.0315 0.0326
Loa Loa (eye worm) TK/ABL protein kinase 0.0023 0.0021 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Trypanosoma brucei glucosidase, putative 0.0037 0.0055 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.02
Loa Loa (eye worm) TK/RYK protein kinase 0.0023 0.0021 0.0021
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0554 0.1323 0.1323
Echinococcus granulosus intermediate filament protein 0.0028 0.0032 0.0031
Echinococcus multilocularis cyclin dependent kinase 9 0.0289 0.0673 0.0672
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0014
Echinococcus granulosus tyrosine protein kinase csk 0.0023 0.0021 0.002
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0023 0.0021 0.099
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0023 0.0021 0.0021
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0023 0.0021 0.002
Plasmodium falciparum MO15-related protein kinase 0.0052 0.0092 0.0107
Brugia malayi Probable isocitrate dehydrogenase 0.0421 0.0997 0.1033
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0023 0.0021 0.0119
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Onchocerca volvulus 0.0023 0.0021 0.099
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0023 0.0021 0.002
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.0119
Loa Loa (eye worm) TK protein kinase 0.0023 0.0021 0.0021
Giardia lamblia Kinase, CAMK CAMKL 0.0052 0.0092 0.0543
Trichomonas vaginalis TK family protein kinase 0.0023 0.0021 0.02
Echinococcus multilocularis thioredoxin glutathione reductase 0.004 0.0061 0.006
Brugia malayi Probable isocitrate dehydrogenase 0.0421 0.0997 0.1033
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0032 0.0033
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.4088 1 1
Echinococcus multilocularis cyclins 0.0063 0.0118 0.0117
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0064 0.0062
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0055 0.0064
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0023 0.0021 0.0119
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.0554 0.1323 0.1323
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0085 0.0172 0.0203
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4 0.0554 0.1323 0.3472
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0023 0.0021 0.0119
Giardia lamblia Protein 21.1 0.0023 0.0021 0.0119
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0023 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0014
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0031 0.0045
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Schistosoma mansoni protein kinase 0.0023 0.0021 0.002
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0023 0.0021 0.002
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Onchocerca volvulus 0.0027 0.0031 0.1491
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0021 0.002
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0064 0.0088
Loa Loa (eye worm) isocitrate dehydrogenase 0.3466 0.8473 0.8781
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Echinococcus granulosus ephrin type A receptor 4 A 0.0023 0.0021 0.002
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0023 0.0021 0.099
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0015 0.0001 0.0001
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0117 0.0117
Leishmania major dihydrolipoamide acetyltransferase precursor, putative 0.0143 0.0315 0.0314
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Schistosoma mansoni cyclin B 0.0092 0.019 0.0189
Wolbachia endosymbiont of Brugia malayi carbamoyl phosphate synthase large subunit 0.0352 0.0827 0.1813
Echinococcus multilocularis cyclins 0.0063 0.0118 0.0117
Echinococcus granulosus retinal guanylyl cyclase 2 0.0023 0.0021 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Echinococcus granulosus Pfam-B_8186 domain containing protein 0.0042 0.0065 0.0065
Trypanosoma cruzi acetyl-CoA carboxylase 0.2531 0.6177 0.729
Schistosoma mansoni ephrin receptor 0.0023 0.0021 0.002
Leishmania major cyclin 0.0092 0.019 0.0189
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0032
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0023 0.0021 0.002
Entamoeba histolytica protein kinase domain containing protein 0.0034 0.0047 0.0276
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.0421 0.0997 0.0996
Echinococcus multilocularis protein KINase family member (kin 25) 0.0023 0.0021 0.002
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0056 0.01 0.0106
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0089 0.0182 0.0202
Loa Loa (eye worm) hypothetical protein 0.0143 0.0315 0.0326
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0052 0.0092 0.0107
Trichomonas vaginalis cyclins, putative 0.0092 0.019 0.1896
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0021 0.002
Trypanosoma cruzi glutamine dependent carbamoyl-phosphate synthase, putative 0.0352 0.0827 0.0976
Plasmodium falciparum dihydrolipoamide acyltransferase component E2 0.0143 0.0315 0.0371
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0023 0.0021 0.002
Echinococcus multilocularis transfer RNA-Thr 0.0023 0.0021 0.002
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.3466 0.8473 0.8473
Brugia malayi hypothetical protein 0.0015 0.0001 0.0001
Echinococcus granulosus tyrosine protein kinase csk 0.0023 0.0021 0.002
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0055 0.0546
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Schistosoma mansoni protein kinase 0.0023 0.0021 0.002
Giardia lamblia Kinase, CAMK CAMKL 0.0052 0.0092 0.0543
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Brugia malayi hypothetical protein 0.0023 0.0021 0.0021
Onchocerca volvulus 0.0041 0.0064 0.3121
Brugia malayi SH2 domain containing protein 0.0023 0.0021 0.0021
Echinococcus granulosus integrin linked protein kinase 0.0023 0.0021 0.002
Echinococcus granulosus tyrosine protein kinase Src64B 0.0023 0.0021 0.002
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0092 0.0913
Onchocerca volvulus 0.0023 0.0021 0.099
Echinococcus granulosus c src tyrosine kinase 0.0023 0.0021 0.002
Echinococcus granulosus tyrosine protein kinase 0.0023 0.0021 0.002
Brugia malayi CXXC zinc finger family protein 0.0033 0.0044 0.0046
Echinococcus multilocularis tyrosine protein kinase shark 0.0023 0.0021 0.002
Echinococcus granulosus tyrosine protein kinase Fyn 0.0023 0.0021 0.002
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0554 0.1323 0.1561
Trypanosoma brucei Mitogen-activated protein kinase 10, putative 0.0052 0.0092 0.0091
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.1557 0.3786 1
Trypanosoma cruzi protein kinase, putative 0.0023 0.0021 0.0024
Brugia malayi Isocitrate dehydrogenase 0.3466 0.8473 0.8781
Echinococcus granulosus tyrosine protein kinase csk 0.0023 0.0021 0.002
Leishmania major protein kinase, putative 0.0023 0.0021 0.002
Echinococcus granulosus cyclin dependent kinase 5 0.0061 0.0113 0.0113
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Plasmodium falciparum glutathione reductase 0.0039 0.0059 0.0069
Echinococcus granulosus peptidase Clp S14 family 0.0056 0.01 0.01
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0023 0.0021 0.002
Loa Loa (eye worm) haspin protein kinase 0.0052 0.0092 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Loa Loa (eye worm) RGC/RGC protein kinase 0.0023 0.0021 0.0021
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0023 0.0021 0.0021
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0042 0.0065 0.0065
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Loa Loa (eye worm) cyclin domain-containing protein 0.0015 0.0001 0.0001
Toxoplasma gondii dihydrolipoyllysine-residue succinyltransferase component of oxoglutarate dehydrogenase 0.0143 0.0315 0.0314
Mycobacterium tuberculosis Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.0421 0.0997 0.1165
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0064 0.0132
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Echinococcus granulosus protein tyrosine kinase 0.0023 0.0021 0.002
Loa Loa (eye worm) RGC/RGC protein kinase 0.0023 0.0021 0.0021
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Trypanosoma brucei unspecified product 0.1024 0.2477 0.2476
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0023 0.0021 0.002
Mycobacterium ulcerans carbamoyl phosphate synthase large subunit 0.0352 0.0827 0.2157
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0005 0.0005
Leishmania major carbamoyl-phosphate synthase, putative 0.0352 0.0827 0.0827
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0023 0.0021 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0092 0.0913
Toxoplasma gondii protein kinase domain-containing protein 0.0023 0.0021 0.002
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0023 0.0021 0.002
Schistosoma mansoni protein kinase 0.0023 0.0021 0.002
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0023 0.0021 0.0119
Echinococcus multilocularis cyclin dependent kinase 1 0.0061 0.0113 0.0113
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.0554 0.1323 0.1561
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0023 0.0021 0.002
Brugia malayi Protein kinase domain containing protein 0.0052 0.0092 0.0095
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0023 0.0021 0.002
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0055 0.0054
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Brugia malayi isocitrate dehydrogenase 0.3466 0.8473 0.8781
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0023 0.0021 0.02
Brugia malayi intermediate filament protein 0.0028 0.0032 0.0033
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0023 0.0021 0.002
Mycobacterium leprae Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) 0.0554 0.1323 0.3442
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Onchocerca volvulus 0.0028 0.0032 0.1544
Trypanosoma cruzi cyclin 6, putative 0.0092 0.019 0.0223
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0023 0.0021 0.0119
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.3466 0.8473 0.8473
Plasmodium vivax glutathione reductase, putative 0.0039 0.0059 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0113 0.0113
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0031 0.0045
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0023 0.0021 0.02
Trichomonas vaginalis cyclin B, putative 0.0092 0.019 0.1896
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0064 0.0062
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0113 0.113
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0055 0.0546
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Brugia malayi C-terminal src kinase protein 1 0.0023 0.0021 0.0021
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0117 0.0117
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Brugia malayi Guanylyl cyclase protein 23 0.0023 0.0021 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Echinococcus multilocularis neuropeptide receptor A26 0.0529 0.1263 0.1262
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Brugia malayi cyclin-dependent kinase 7 homolog 0.0052 0.0092 0.0095
Brugia malayi Cyclin, N-terminal domain containing protein 0.0015 0.0001 0.0001
Entamoeba histolytica cyclin family protein 0.0063 0.0118 0.0699
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.1557 0.3786 0.4469
Echinococcus granulosus cyclin dependent kinase 1 0.0061 0.0113 0.0113
Echinococcus multilocularis cyclin dependent kinase 0.0061 0.0113 0.0113
Trypanosoma brucei dihydrolipoamide branched chain transacylase, putative 0.0143 0.0315 0.0314
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0023 0.0021 0.0119
Echinococcus granulosus activin receptor type 0.0034 0.0047 0.0046
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0005 0.0005
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0014 0.0015
Loa Loa (eye worm) cyclin domain-containing protein 0.0063 0.0118 0.0122
Echinococcus multilocularis protein kinase 0.0023 0.0021 0.002
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0023 0.0021 0.002
Toxoplasma gondii ABC1 family protein 0.0041 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.0028 0.0032 0.0033
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0064 0.0066
Loa Loa (eye worm) hypothetical protein 0.0256 0.0593 0.0614
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0023 0.0021 0.002
Trypanosoma cruzi glutamine-dependent carbamoyl-phosphate synthetase, putative 0.0352 0.0827 0.0976
Wolbachia endosymbiont of Brugia malayi branched-chain alpha-keto acid dehydrogenase subunit E2 0.0143 0.0315 0.0395
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0052 0.0092 0.0095
Leishmania major serine/threonine kinase-like protein, putative 0.0052 0.0092 0.0091
Trypanosoma cruzi CYC2-like cyclin, putative 0.0092 0.019 0.0223
Onchocerca volvulus 0.0023 0.0021 0.099
Mycobacterium tuberculosis Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 0.0554 0.1323 0.1551
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0023 0.0021 0.0119
Echinococcus granulosus dnaJ subfamily B 0.0468 0.1113 0.1112
Loa Loa (eye worm) hypothetical protein 0.0041 0.0064 0.0066
Brugia malayi GSG2 0.0042 0.0065 0.0068
Giardia lamblia Kinase, CMGC CDK 0.0061 0.0113 0.0673
Brugia malayi Furin-like cysteine rich region family protein 0.0023 0.0021 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Echinococcus granulosus cyclin B 0.0092 0.019 0.0189
Echinococcus multilocularis heat shock protein 70 0.0023 0.0021 0.002
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0023 0.0021 0.002
Mycobacterium tuberculosis Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) 0.0554 0.1323 0.1551
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.3466 0.8473 1
Loa Loa (eye worm) TK protein kinase 0.0023 0.0021 0.0021
Brugia malayi hypothetical protein 0.0023 0.0021 0.0021
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0064 0.0062
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Entamoeba histolytica cell division protein kinase 2, putative 0.0061 0.0113 0.0673
Schistosoma mansoni protein kinase 0.0023 0.0021 0.002
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0061 0.0113 0.0117
Chlamydia trachomatis biotin carboxylase 0.1414 0.3435 1
Brugia malayi ephrin receptor 1 precursor 0.0023 0.0021 0.0021
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.0119
Entamoeba histolytica tyrosin kinase, putative 0.0023 0.0021 0.0119
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0034 0.0047 0.0055
Loa Loa (eye worm) hypothetical protein 0.0256 0.0593 0.0614
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0023 0.0021 0.0119
Echinococcus multilocularis musashi 0.0028 0.0032 0.0031
Brugia malayi hypothetical protein 0.0023 0.0021 0.0021
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Echinococcus granulosus tyrosine protein kinase pr2 0.0023 0.0021 0.002
Echinococcus multilocularis geminin 0.0192 0.0435 0.0434
Schistosoma mansoni cpg binding protein 0.0035 0.0049 0.0048
Loa Loa (eye worm) hypothetical protein 0.0041 0.0064 0.0066
Echinococcus granulosus serine:threonine protein kinase haspin 0.0042 0.0065 0.0065
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0064 0.0063
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0092 0.0091
Trypanosoma brucei trypanothione reductase 0.0039 0.0059 0.0059
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0064 0.0062
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.3466 0.8473 0.8473
Trypanosoma brucei cdc2-related kinase 3 0.0061 0.0113 0.0113
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0095 0.0099
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0014
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.1557 0.3786 0.3786
Loa Loa (eye worm) CYL-1 protein 0.0015 0.0001 0.0001
Echinococcus granulosus isocitrate dehydrogenase NAD 0.0421 0.0997 0.0996
Echinococcus multilocularis cyclins 0.0063 0.0118 0.0117
Mycobacterium tuberculosis Conserved protein 0.0041 0.0064 0.0062
Trichomonas vaginalis cyclin A, putative 0.0092 0.019 0.1896
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Trypanosoma brucei Flagellum attachment zone protein 20 0.0023 0.0021 0.002
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0023 0.0021 0.002
Trichomonas vaginalis cyclin B, putative 0.0092 0.019 0.1896
Echinococcus granulosus tyrosine protein kinase Fyn 0.0023 0.0021 0.002
Schistosoma mansoni hypothetical protein 0.0192 0.0435 0.0434
Entamoeba histolytica hypothetical protein 0.0042 0.0065 0.0386
Echinococcus multilocularis lysosomal alpha glucosidase 0.0168 0.0376 0.0376
Echinococcus granulosus serine:threonine protein kinase haspin 0.0042 0.0065 0.0065
Plasmodium vivax tyrosine kinase-like protein, putative 0.0023 0.0021 0.0024
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.2958 0.7227 0.8529
Echinococcus granulosus serine:threonine protein kinase NLK 0.0052 0.0092 0.0091
Onchocerca volvulus 0.0023 0.0021 0.099
Giardia lamblia Kinase 0.0023 0.0021 0.0119
Brugia malayi integrin-linked kinase 0.0023 0.0021 0.0021
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0052 0.0092 0.0091
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0085 0.0172 0.042
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0023 0.0021 0.002
Echinococcus multilocularis tyrosine kinase 0.0023 0.0021 0.002
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0031 0.018
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0023 0.0021 0.0021
Toxoplasma gondii hypothetical protein 0.0029 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0041 0.0064 0.0066
Onchocerca volvulus 0.0028 0.0032 0.1544
Entamoeba histolytica hypothetical protein, conserved 0.0023 0.0021 0.0119
Echinococcus multilocularis ephrin type A receptor 4 A 0.0023 0.0021 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Brugia malayi hypothetical protein 0.0256 0.0593 0.0614
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0056 0.01 0.0106
Plasmodium falciparum lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex 0.0143 0.0315 0.0371
Wolbachia endosymbiont of Brugia malayi Acetyl-CoA carboxylase, carboxyltransferase component 0.0554 0.1323 0.3185
Trypanosoma brucei mitotic cyclin 6 0.0092 0.019 0.0189
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.0421 0.0997 0.0996
Loa Loa (eye worm) cyclin domain-containing protein 0.0015 0.0001 0.0001
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.1557 0.3786 0.3786
Brugia malayi Immunoglobulin I-set domain containing protein 0.028 0.065 0.0674
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0085 0.0172 0.0203
Schistosoma mansoni peptidase Clp (S14 family) 0.0085 0.0172 0.0172
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Plasmodium falciparum protein kinase, putative 0.0034 0.0047 0.0055
Brugia malayi Immunoglobulin I-set domain containing protein 0.0256 0.0593 0.0614
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.2958 0.7227 0.8529
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0021 0.002
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Brugia malayi Protein kinase domain containing protein 0.0061 0.0113 0.0117
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.0119
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0032 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Loa Loa (eye worm) TK/DDR protein kinase 0.0023 0.0021 0.0021
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Echinococcus multilocularis cyclin B 0.0092 0.019 0.0189
Giardia lamblia Kinase, CAMK CAMKL 0.0052 0.0092 0.0543
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0023 0.0021 0.002
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Schistosoma mansoni tyrosine protein kinase 0.0023 0.0021 0.002
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0092 0.0913
Onchocerca volvulus 0.0023 0.0021 0.099
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0023 0.0021 0.0119
Mycobacterium ulcerans branched-chain alpha-keto acid dehydrogenase subunit E2 0.0143 0.0315 0.0799
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0044 0.0046
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide acyltransferase E2 component 0.0143 0.0315 0.0395
Entamoeba histolytica protein kinase domain containing protein 0.0052 0.0092 0.0543
Loa Loa (eye worm) TK/EGFR protein kinase 0.0023 0.0021 0.0021
Trichomonas vaginalis cyclin D, putative 0.0063 0.0118 0.1174
Echinococcus multilocularis activin receptor type 0.0034 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Mycobacterium ulcerans hypothetical protein 0.0143 0.0315 0.0799
Trichomonas vaginalis serine/threonine kinase, putative 0.0052 0.0092 0.0913
Leishmania major hypothetical protein, conserved 0.0041 0.0064 0.0063
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0023 0.0021 0.002
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Toxoplasma gondii isocitrate dehydrogenase 0.3466 0.8473 0.8473
Brugia malayi Fibronectin type III domain containing protein 0.0256 0.0593 0.0614
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0055 0.0546
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0023 0.0021 0.002
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.3466 0.8473 1
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0031 0.0032
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Echinococcus granulosus Cell division cycle 2 protein kinase 0.0052 0.0092 0.0091
Echinococcus granulosus tyrosine protein kinase Src42A 0.0023 0.0021 0.002
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0085 0.0172 0.042
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0092 0.0913
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0023 0.0021 0.002
Schistosoma mansoni protein kinase 0.0023 0.0021 0.002
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0063 0.0118 0.0117
Mycobacterium ulcerans lipase LipD 0.0041 0.0064 0.0132
Brugia malayi bone morphogenetic protein type 1 receptor 0.0023 0.0021 0.0021
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Leishmania major propionyl-coa carboxylase beta chain, putative 0.0554 0.1323 0.1323
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0064 0.0632
Trichomonas vaginalis cyclin B3, putative 0.0063 0.0118 0.1174
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Echinococcus multilocularis FL cytokine receptor 0.0023 0.0021 0.002
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0117 0.0117
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0092 0.0913
Loa Loa (eye worm) SRC-1 0.0023 0.0021 0.0021
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Brugia malayi Cyclin, N-terminal domain containing protein 0.0015 0.0001 0.0001
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.3466 0.8473 0.8473
Echinococcus multilocularis cyclin B3 1 0.0063 0.0118 0.0117
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0023 0.0021 0.002
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.1557 0.3786 1
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0052 0.0092 0.0107
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0064 0.0063
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.3466 0.8473 0.8473
Echinococcus multilocularis Immunoglobulin 0.0256 0.0593 0.0592
Brugia malayi Probable ClpP-like protease 0.0085 0.0172 0.0179
Trichomonas vaginalis cyclins, putative 0.0092 0.019 0.1896
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0143 0.0315 0.0314
Loa Loa (eye worm) hypothetical protein 0.0256 0.0593 0.0614
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0055 0.0054
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0014
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0005 0.0005
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0023 0.0021 0.002
Echinococcus multilocularis activated cdc42 kinase 1 0.0023 0.0021 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.02
Schistosoma mansoni hypothetical protein 0.0017 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Entamoeba histolytica tyrosin kinase, putative 0.0023 0.0021 0.0119
Entamoeba histolytica tyrosin kinase, putative 0.0023 0.0021 0.0119
Loa Loa (eye worm) haspin protein kinase 0.0042 0.0065 0.0068
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0023 0.0021 0.002
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0039 0.0059 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0092 0.0913
Echinococcus multilocularis microtubule associated protein 2 0.0751 0.1807 0.1806
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.02
Leishmania major mitogen-activated protein kinase, putative,map kinase-like protein 0.0052 0.0092 0.0091
Echinococcus granulosus insulin receptor 0.0023 0.0021 0.002
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0055 0.0546
Echinococcus multilocularis cyclins 0.0063 0.0118 0.0117
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0023 0.0021 0.002
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0031 0.0045
Trichomonas vaginalis cyclin B, putative 0.0092 0.019 0.1896
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0061 0.0113 0.0117
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0029 0.0035 0.0041
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0063 0.0118 0.0117
Echinococcus multilocularis Immunoglobulin 0.0256 0.0593 0.0592
Plasmodium vivax protein kinase Crk2 0.0061 0.0113 0.0133
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.0421 0.0997 0.1033
Echinococcus granulosus tyrosine protein kinase Srms 0.0023 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0041 0.0064 0.0066
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0023 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0256 0.0593 0.0614
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0023 0.0021 0.002
Echinococcus multilocularis cyclin dependent kinase 5 0.0061 0.0113 0.0113
Trichomonas vaginalis STE family protein kinase 0.0023 0.0021 0.02
Mycobacterium leprae PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) 0.0421 0.0997 0.2573
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0023 0.0021 0.0021
Echinococcus multilocularis Biotin lipoyl attachment 0.0143 0.0315 0.0314
Brugia malayi Cyclin, N-terminal domain containing protein 0.0092 0.019 0.0196
Echinococcus multilocularis insulin receptor 0.0023 0.0021 0.002
Loa Loa (eye worm) TK/EPH protein kinase 0.0023 0.0021 0.0021
Mycobacterium tuberculosis Probable reductase 0.0089 0.0182 0.0202
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Brugia malayi hypothetical protein 0.0015 0.0001 0.0001
Schistosoma mansoni alpha glucosidase 0.0037 0.0055 0.0054
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0085 0.0172 0.0464
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0034 0.0047 0.0055
Plasmodium vivax protein kinase, putative 0.0023 0.0021 0.0024
Brugia malayi Cyclin, N-terminal domain containing protein 0.0015 0.0001 0.0001
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Echinococcus granulosus cyclins 0.0063 0.0118 0.0117
Loa Loa (eye worm) beta-lactamase 0.0041 0.0064 0.0066
Echinococcus granulosus cyclin dependent kinase 9 0.0247 0.0571 0.057
Brugia malayi dihydrolipoamide S-acetyltransferase precursor, putative 0.0143 0.0315 0.0326
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0023 0.0021 0.0119
Echinococcus multilocularis tyrosine protein kinase Abl 0.0023 0.0021 0.002
Giardia lamblia Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative 0.0697 0.1675 1
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Brugia malayi Cyclin, N-terminal domain containing protein 0.0015 0.0001 0.0001
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0261 0.0603 0.07
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Echinococcus multilocularis protein kinase 0.0023 0.0021 0.002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0089 0.0182 0.0202
Toxoplasma gondii hypothetical protein 0.0048 0.008 0.008
Brugia malayi Glycosyl hydrolases family 31 protein 0.0168 0.0376 0.039
Entamoeba histolytica serine/threonine kinase, putative 0.0023 0.0021 0.0119
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0143 0.0315 0.0371
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0032
Trypanosoma cruzi dihydrolipoamide acetyltransferase, putative 0.0143 0.0315 0.0371
Echinococcus multilocularis natriuretic peptide receptor 1 0.0023 0.0021 0.002
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.1557 0.3786 0.4462
Entamoeba histolytica serine/threonine kinase, putative 0.0023 0.0021 0.0119
Schistosoma mansoni lamin 0.0028 0.0032 0.0031
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.0421 0.0997 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0023 0.0021 0.002
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0837 0.2019 0.2018
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0055 0.0546
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0113 0.113
Mycobacterium ulcerans pyruvate carboxylase 0.1557 0.3786 1
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Trypanosoma brucei glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative 0.0352 0.0827 0.0827
Echinococcus granulosus cyclin dependent kinase 9 0.0289 0.0673 0.0672
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0023 0.0021 0.002
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0023 0.0021 0.002
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0023 0.0021 0.002
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0023 0.0021 0.0021
Schistosoma mansoni kinase 0.0247 0.0571 0.057
Schistosoma mansoni intermediate filament proteins 0.0028 0.0032 0.0031
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0117 0.0275
Schistosoma mansoni protein kinase 0.0034 0.0047 0.0046
Schistosoma mansoni protein kinase 0.0034 0.0047 0.0046
Toxoplasma gondii thioredoxin reductase 0.0039 0.0059 0.0059
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0023 0.0021 0.0119
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0052 0.0092 0.0107
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0099 0.0207 0.0468
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0113 0.113
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0117 0.0275
Entamoeba histolytica cysteine surface protein, putative 0.0023 0.0021 0.0119
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Echinococcus multilocularis lamin 0.0028 0.0032 0.0031
Brugia malayi cyclin fold protein 1 variant b 0.0015 0.0001 0.0001
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0256 0.0593 0.0592
Trichomonas vaginalis cyclins, putative 0.0063 0.0118 0.1174
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Schistosoma mansoni unc-13 (munc13) 0.0421 0.0997 0.0996
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0061 0.0113 0.0113
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.02
Loa Loa (eye worm) hypothetical protein 0.0027 0.003 0.0032
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0023 0.0021 0.0119
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0055 0.0546
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0143 0.0315 0.0314
Echinococcus granulosus epidermal growth factor receptor 0.0023 0.0021 0.002
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0035 0.0041
Schistosoma mansoni serine/threonine kinase 0.0052 0.0092 0.0091
Echinococcus granulosus thioredoxin glutathione reductase 0.004 0.0061 0.006
Leishmania major dihydrolipoamide branched chain transacylase, putative 0.0143 0.0315 0.0314
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0055 0.0054
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Trypanosoma cruzi cdc2-related kinase 1 0.0061 0.0113 0.0133
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0023 0.0021 0.002
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Loa Loa (eye worm) hypothetical protein 0.005 0.0087 0.009
Toxoplasma gondii carbamoylphosphate synthetase 0.0352 0.0827 0.0827
Echinococcus multilocularis epidermal growth factor receptor 0.0023 0.0021 0.002
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0014 0.0003
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0095 0.0099
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0256 0.0593 0.0592
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0031 0.0045
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0031 0.018
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.3466 0.8473 1
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.0052 0.0092 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Onchocerca volvulus 0.0023 0.0021 0.099
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0085 0.0172 0.0172
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0031 0.018
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0031 0.0032
Loa Loa (eye worm) TK protein kinase 0.0023 0.0021 0.0021
Mycobacterium tuberculosis Probable dehydrogenase 0.0089 0.0182 0.0202
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0014
Plasmodium vivax dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, putative 0.0143 0.0315 0.0371
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0135 0.0134
Loa Loa (eye worm) cyclin domain-containing protein 0.0015 0.0001 0.0001
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.1557 0.3786 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0031 0.003
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0023 0.0021 0.002
Echinococcus multilocularis neuroglian 0.0256 0.0593 0.0592
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0005 0.0005
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0023 0.0021 0.0021
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0005 0.0005
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 5 AccD5 0.0554 0.1323 0.3472
Schistosoma mansoni hypothetical protein 0.0017 0.0005 0.0005
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0052 0.0092 0.0107
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0085 0.0172 0.0464
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0064 0.0632
Echinococcus multilocularis cyclin b3 0.0063 0.0118 0.0117
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0031 0.003
Echinococcus multilocularis cyclins 0.0063 0.0118 0.0117
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Echinococcus multilocularis cyclin dependent kinase 1 0.0061 0.0113 0.0113
Echinococcus multilocularis cyclins 0.0063 0.0118 0.0117
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0023 0.0021 0.002
Echinococcus multilocularis tyrosine protein kinase csk 0.0023 0.0021 0.002
Schistosoma mansoni protein kinase 0.0034 0.0047 0.0046
Trichomonas vaginalis cyclin B, putative 0.0092 0.019 0.1896
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0064 0.0132
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Echinococcus multilocularis tyrosine protein kinase Srms 0.0023 0.0021 0.002
Echinococcus granulosus neuropeptide receptor A26 0.0529 0.1263 0.1262
Schistosoma mansoni ephrin receptor 0.0023 0.0021 0.002
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.0119
Loa Loa (eye worm) hypothetical protein 0.0092 0.019 0.0196
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0554 0.1323 0.1561
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.1557 0.3786 0.3786
Echinococcus granulosus tyrosine kinase 0.0023 0.0021 0.002
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0089 0.0182 0.0202
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Giardia lamblia Hypothetical protein 0.0063 0.0118 0.0699
Echinococcus multilocularis dnaJ subfamily B 0.0468 0.1113 0.1112
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0031 0.0023
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0099 0.0207 0.0231
Echinococcus granulosus dihydrolipoyllysine residue succinyltransferase 0.0143 0.0315 0.0314
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Onchocerca volvulus 0.0023 0.0021 0.099
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Mycobacterium tuberculosis Biotinylated protein TB7.3 0.0143 0.0315 0.0359
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0117 0.0126
Schistosoma mansoni alpha-glucosidase 0.0145 0.0319 0.0318
Brugia malayi beta-lactamase 0.0041 0.0064 0.0066
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0064 0.0074
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0168 0.0376 0.039
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Chlamydia trachomatis dihydrolipoamide acetyltransferase 0.0143 0.0315 0.0881
Loa Loa (eye worm) hypothetical protein 0.0029 0.0035 0.0037
Trypanosoma brucei 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0554 0.1323 0.1323
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0023 0.0021 0.0021
Echinococcus granulosus twitchin 0.0267 0.0619 0.0618
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.0119
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.0421 0.0997 0.1033
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0247 0.0571 0.0592
Echinococcus multilocularis raf serine:threonine protein kinase 0.0023 0.0021 0.002
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0064 0.0062
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0571 0.057
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0023 0.0021 0.002
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Trypanosoma brucei isocitrate dehydrogenase, putative 0.3466 0.8473 0.8473
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0023 0.0021 0.002
Chlamydia trachomatis acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 0.0554 0.1323 0.3828
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Entamoeba histolytica protein kinase domain containing protein 0.0247 0.0571 0.3406
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0143 0.0315 0.0371
Schistosoma mansoni protein tyrosine kinase 0.0023 0.0021 0.002
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.3466 0.8473 1
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.1557 0.3786 0.4462
Trypanosoma cruzi dihydrolipoamide branched chain transacylase, putative 0.0143 0.0315 0.0371
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.4088 1 1
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.0554 0.1323 0.1323
Echinococcus granulosus retinal guanylyl cyclase 2 0.0023 0.0021 0.002
Plasmodium vivax tyrosine kinase-like protein, putative 0.0023 0.0021 0.0024
Trichomonas vaginalis cyclin B, putative 0.0063 0.0118 0.1174
Toxoplasma gondii protein kinase 0.0023 0.0021 0.002
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0117 0.0117
Echinococcus granulosus roundabout 2 0.0256 0.0593 0.0592
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0092 0.0913
Toxoplasma gondii dihydrolipoamide acyltransferase, putative 0.0143 0.0315 0.0314
Trypanosoma brucei acetyl-CoA carboxylase 0.4088 1 1
Trypanosoma cruzi cyclin, putative 0.0092 0.019 0.0223
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0055 0.0054
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Brugia malayi Cyclin, N-terminal domain containing protein 0.0092 0.019 0.0196
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0117 0.0275
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Leishmania major protein kinase, putative 0.0034 0.0047 0.0046
Mycobacterium ulcerans 3-isopropylmalate dehydrogenase 0.0421 0.0997 0.2606
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0032
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0352 0.0827 0.0827
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0031 0.0045
Schistosoma mansoni cyclin B3 0.0063 0.0118 0.0117
Entamoeba histolytica hypothetical protein 0.0023 0.0021 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Trypanosoma cruzi cdc2-related kinase 3 0.0061 0.0113 0.0133
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0023 0.0021 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Trypanosoma cruzi protein kinase, putative 0.0023 0.0021 0.0024
Schistosoma mansoni vesicular amine transporter 0.0256 0.0593 0.0592
Toxoplasma gondii acyl-CoA carboxyltransferase beta chain, putative 0.0554 0.1323 0.1323
Schistosoma mansoni protein kinase 0.0052 0.0092 0.0091
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0023 0.0021 0.002
Echinococcus multilocularis isocitrate dehydrogenase 0.3466 0.8473 0.8473
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0064 0.0062
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0042 0.0065 0.0065
Trypanosoma brucei 2-oxoglutarate dehydrogenase E2 component, putative 0.0143 0.0315 0.0314
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Loa Loa (eye worm) thioredoxin reductase 0.0039 0.0059 0.0061
Schistosoma mansoni hypothetical protein 0.0042 0.0065 0.0065
Leishmania major carboxylase, putative 0.1557 0.3786 0.3786
Loa Loa (eye worm) hypothetical protein 0.0023 0.0021 0.0021
Loa Loa (eye worm) RGC/RGC protein kinase 0.0023 0.0021 0.0021
Mycobacterium tuberculosis Conserved protein 0.0041 0.0064 0.0062
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Brugia malayi Tyrosine-protein kinase abl-1 0.0023 0.0021 0.0021
Schistosoma mansoni carbamoyl-phosphate synthetase 0.0352 0.0827 0.0827
Onchocerca volvulus 0.0023 0.0021 0.099
Echinococcus granulosus natriuretic peptide receptor 1 0.0023 0.0021 0.002
Mycobacterium leprae Probable biotinylated protein homolog TB7.3 0.0143 0.0315 0.0757
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Mycobacterium leprae ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 0.0554 0.1323 0.3442
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Echinococcus granulosus cyclins 0.0063 0.0118 0.0117
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0055 0.0057
Mycobacterium ulcerans hypothetical protein 0.0041 0.0064 0.0132
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0061 0.0113 0.0113
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Echinococcus multilocularis dihydrolipoyllysine residue succinyltransferase 0.0143 0.0315 0.0314
Echinococcus multilocularis tyrosine protein kinase csk 0.0023 0.0021 0.002
Entamoeba histolytica cyclin family protein 0.0063 0.0118 0.0699
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0023 0.0021 0.002
Echinococcus multilocularis cpg binding protein 0.0035 0.0049 0.0048
Schistosoma mansoni hypothetical protein 0.0017 0.0005 0.0005
Echinococcus multilocularis peptidase Clp (S14 family) 0.0056 0.01 0.01
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4_2 0.0554 0.1323 0.3472
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0023 0.0021 0.0021
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0029 0.0035 0.0012
Onchocerca volvulus 0.0041 0.0064 0.3121
Echinococcus multilocularis tyrosine protein kinase Blk 0.0023 0.0021 0.002
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Leishmania major acetyl-CoA carboxylase, putative 0.4088 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Loa Loa (eye worm) hypothetical protein 0.0041 0.0064 0.0066
Mycobacterium ulcerans acetyl-/propionyl-CoA carboxylase subunit beta 0.0554 0.1323 0.3472
Plasmodium falciparum cyclin 0.0063 0.0118 0.0138
Loa Loa (eye worm) TK/KIN16 protein kinase 0.028 0.065 0.0674
Echinococcus multilocularis tyrosine kinase 0.0023 0.0021 0.002
Schistosoma mansoni alpha-glucosidase 0.0145 0.0319 0.0318
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.0421 0.0997 0.0996
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0055 0.0057
Echinococcus granulosus dihydrolipoyllysine residue acetyltransferase 0.0143 0.0315 0.0314
Echinococcus multilocularis lamin dm0 0.0028 0.0032 0.0031
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Chlamydia trachomatis acetyl-CoA carboxylase biotin carboxyl carrier protein 0.0143 0.0315 0.0881
Entamoeba histolytica receptor protein kinase, putative 0.0023 0.0021 0.0119
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0034 0.0047 0.0046
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Schistosoma mansoni hypothetical protein 0.0468 0.1113 0.1112
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0085 0.0172 0.4897
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0092 0.0913
Plasmodium falciparum tyrosine kinase-like protein 0.0023 0.0021 0.0024
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E2 0.0143 0.0315 0.0314
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0117 0.0117
Loa Loa (eye worm) serine/threonine protein kinase 0.0023 0.0021 0.0021
Brugia malayi protein-tyrosine kinase 0.0023 0.0021 0.0021
Trypanosoma cruzi dihydrolipoamide acetyltransferase precursor, putative 0.0143 0.0315 0.0371
Loa Loa (eye worm) hypothetical protein 0.0085 0.0172 0.0179
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0055 0.0546
Echinococcus granulosus tyrosine kinase 0.0023 0.0021 0.002
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Echinococcus granulosus protein kinase 0.0023 0.0021 0.002
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Schistosoma mansoni protein kinase 0.0023 0.0021 0.002
Trichomonas vaginalis protein kinase atmrk1, putative 0.0052 0.0092 0.0913
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.3466 0.8473 1
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0055 0.0064
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.1557 0.3786 0.3786
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Echinococcus granulosus lysosomal alpha glucosidase 0.0168 0.0376 0.0376
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Mycobacterium ulcerans hypothetical protein 0.0027 0.0031 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Loa Loa (eye worm) TK/Met protein kinase 0.0023 0.0021 0.0021
Entamoeba histolytica tartrate dehydrogenase, putative 0.0421 0.0997 0.595
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0064 0.0632
Echinococcus granulosus activated cdc42 kinase 1 0.0023 0.0021 0.002
Loa Loa (eye worm) TK/ACK protein kinase 0.0023 0.0021 0.0021
Brugia malayi cyclin-dependent kinase 9 0.0247 0.0571 0.0592
Toxoplasma gondii biotin-requiring enzyme domain-containing protein 0.0143 0.0315 0.0314
Toxoplasma gondii isocitrate dehydrogenase 0.3466 0.8473 0.8473
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0023 0.0021 0.0119
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Loa Loa (eye worm) hypothetical protein 0.0256 0.0593 0.0614
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0092 0.0913
Brugia malayi Protein kinase domain containing protein 0.0023 0.0021 0.0021
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0055 0.0325
Onchocerca volvulus 0.0092 0.019 0.937
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Echinococcus multilocularis receptor type guanylyl cyclase 0.0023 0.0021 0.002
Entamoeba histolytica tyrosine kinase, putative 0.0023 0.0021 0.0119
Echinococcus granulosus receptor type guanylyl cyclase 0.0023 0.0021 0.002
Onchocerca volvulus 0.0097 0.0202 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0023 0.0021 0.002
Entamoeba histolytica cyclin, putative 0.0063 0.0118 0.0699
Echinococcus granulosus cyclin dependent kinase 0.0061 0.0113 0.0113
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0031 0.0045
Entamoeba histolytica protein kinase, putative 0.0023 0.0021 0.0119
Plasmodium falciparum tyrosine kinase-like protein 0.0023 0.0021 0.0024
Trichomonas vaginalis AGC family protein kinase 0.0052 0.0092 0.0913
Giardia lamblia G2/mitotic-specific cyclin B 0.0092 0.019 0.1128
Entamoeba histolytica protein kinase domain containing protein 0.0023 0.0021 0.0119
Plasmodium vivax carbamoyl phosphate synthetase, putative 0.0352 0.0827 0.0976
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0055 0.0325
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Plasmodium falciparum protein kinase 5 0.0061 0.0113 0.0133
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Onchocerca volvulus 0.0023 0.0021 0.099
Loa Loa (eye worm) TK/ALK protein kinase 0.0023 0.0021 0.0021
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0064 0.0074
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.1557 0.3786 1
Echinococcus multilocularis dihydrolipoyllysine residue acetyltransferase 0.0143 0.0315 0.0314
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0023 0.0021 0.0021
Loa Loa (eye worm) RGC/RGC protein kinase 0.0023 0.0021 0.0021
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0023 0.0021 0.002
Loa Loa (eye worm) haspin protein kinase 0.0042 0.0065 0.0068
Echinococcus multilocularis GPCR, family 2 0.0017 0.0005 0.0005
Schistosoma mansoni tyrosine kinase 0.0023 0.0021 0.002
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02
Loa Loa (eye worm) glutathione reductase 0.0039 0.0059 0.0061
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0023 0.0021 0.0119
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0023 0.0021 0.0021
Echinococcus granulosus cpg binding protein 0.0035 0.0049 0.0048
Schistosoma mansoni dihydrolipoamide S-acetyltransferase 0.0143 0.0315 0.0314
Loa Loa (eye worm) TK/FER protein kinase 0.0023 0.0021 0.0021
Mycobacterium leprae Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) 0.0554 0.1323 0.3442
Mycobacterium ulcerans beta-lactamase 0.0041 0.0064 0.0132
Trypanosoma cruzi cdc2-related kinase 1 0.0061 0.0113 0.0133
Echinococcus granulosus cyclins 0.0063 0.0118 0.0117
Trichomonas vaginalis TKL family protein kinase 0.0023 0.0021 0.02

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 6.25 ug ml-1 Evaluated for its antimicrobial activity against Escherichia coli (25922) ChEMBL. 11714611

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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