Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0364 | 0.2014 | 0.1944 |
Echinococcus granulosus | protein jagged 1 | 0.0139 | 0.0635 | 0.0635 |
Schistosoma mansoni | hypothetical protein | 0.0228 | 0.1179 | 0.1179 |
Loa Loa (eye worm) | hexokinase | 0.167 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0191 | 0.0951 | 0.0951 |
Echinococcus multilocularis | fibropellin Ia | 0.0139 | 0.0635 | 0.0635 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0139 | 0.0635 | 0.0554 |
Brugia malayi | hexokinase type II | 0.0531 | 0.3033 | 0.3033 |
Brugia malayi | hypothetical protein | 0.0067 | 0.0195 | 0.0195 |
Schistosoma mansoni | plexin | 0.0392 | 0.2179 | 0.2179 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0139 | 0.0635 | 0.0635 |
Schistosoma mansoni | fibrocystin l | 0.0072 | 0.0223 | 0.0223 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0139 | 0.0635 | 0.0635 |
Onchocerca volvulus | 0.0139 | 0.0635 | 0.0449 | |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.0785 | 0.0785 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0067 | 0.0195 | 0.0195 |
Schistosoma mansoni | cell polarity protein | 0.0139 | 0.0635 | 0.0635 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus multilocularis | slit 2 protein | 0.0139 | 0.0635 | 0.0635 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0072 | 0.0223 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus multilocularis | notch | 0.0139 | 0.0635 | 0.0635 |
Echinococcus granulosus | transcription factor collier | 0.0072 | 0.0223 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.0785 | 0.0785 |
Onchocerca volvulus | Hexokinase homolog | 0.1048 | 0.6193 | 0.6118 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0223 | 1 |
Echinococcus granulosus | enteropeptidase | 0.0067 | 0.0195 | 0.0195 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0067 | 0.0192 | 0.011 |
Echinococcus multilocularis | transcription factor collier | 0.0072 | 0.0223 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.2014 | 0.2014 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0067 | 0.0195 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.2014 | 0.2014 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0364 | 0.2014 | 0.2014 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0223 | 0.0223 |
Trypanosoma cruzi | hexokinase, putative | 0.167 | 1 | 1 |
Loa Loa (eye worm) | sema domain-containing protein | 0.0164 | 0.0785 | 0.0785 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.0223 | 0.0223 |
Entamoeba histolytica | hexokinase 1 | 0.167 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Brugia malayi | Fibulin-1 precursor | 0.0364 | 0.2014 | 0.2014 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.0785 | 0.0785 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0091 | 0.034 | 0.012 |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0139 | 0.0635 | 0.0449 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Onchocerca volvulus | 0.0139 | 0.0635 | 0.0449 | |
Schistosoma mansoni | egf-like domain protein | 0.0364 | 0.2014 | 0.2014 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus granulosus | Mastin | 0.0067 | 0.0195 | 0.0195 |
Onchocerca volvulus | 0.0139 | 0.0635 | 0.0449 | |
Loa Loa (eye worm) | hexokinase | 0.1048 | 0.6193 | 0.6193 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0223 | 1 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0049 | 0.0083 | 0.3698 |
Leishmania major | hexokinase, putative | 0.167 | 1 | 1 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Schistosoma mansoni | notch | 0.0139 | 0.0635 | 0.0635 |
Schistosoma mansoni | notch | 0.0139 | 0.0635 | 0.0635 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0039 | 0.0023 | 0.0023 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0072 | 0.0223 | 1 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Echinococcus multilocularis | protein jagged 1 | 0.0139 | 0.0635 | 0.0635 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0067 | 0.0195 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.2014 | 0.2014 |
Echinococcus granulosus | protein jagged 1 | 0.0139 | 0.0635 | 0.0635 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0223 | 1 |
Onchocerca volvulus | Neurogenic locus notch protein homolog | 0.0139 | 0.0635 | 0.0449 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0036 | 0.0008 | 0.0342 |
Plasmodium falciparum | hexokinase | 0.167 | 1 | 0.5 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0195 | 0.0195 |
Onchocerca volvulus | 0.0392 | 0.2179 | 0.2024 | |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | trypsin family protein | 0.0067 | 0.0195 | 0.0195 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Trypanosoma brucei | hexokinase | 0.167 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Onchocerca volvulus | Arrow homolog | 0.0364 | 0.2014 | 0.1855 |
Brugia malayi | EGF-like domain containing protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0067 | 0.0195 | 0.0195 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0139 | 0.0635 | 0.0635 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0072 | 0.0223 | 1 |
Onchocerca volvulus | Putative cubilin | 0.0139 | 0.0635 | 0.0449 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0195 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Brugia malayi | DNA-binding protein LAG-1 | 0.0072 | 0.0223 | 0.0223 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0139 | 0.0635 | 0.0635 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.0223 | 0.0223 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Brugia malayi | IPT/TIG domain containing protein | 0.0072 | 0.0223 | 0.0223 |
Schistosoma mansoni | slit | 0.0139 | 0.0635 | 0.0635 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0072 | 0.0223 | 1 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0067 | 0.0192 | 0.011 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.0785 | 0.0785 |
Echinococcus multilocularis | exocyst complex component 2 | 0.0072 | 0.0223 | 0.0223 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0139 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Onchocerca volvulus | 0.167 | 1 | 1 | |
Echinococcus multilocularis | hexokinase | 0.167 | 1 | 1 |
Echinococcus multilocularis | dual 3',5' cyclic AMP and GMP phosphodiesterase | 0.0067 | 0.0192 | 0.0192 |
Echinococcus granulosus | slit 2 protein | 0.0139 | 0.0635 | 0.0635 |
Brugia malayi | Cadherin domain containing protein | 0.0139 | 0.0635 | 0.0635 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Loa Loa (eye worm) | PDE1B protein | 0.0191 | 0.0951 | 0.0951 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0039 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0364 | 0.2014 | 0.2014 |
Echinococcus granulosus | exocyst complex component 2 | 0.0072 | 0.0223 | 0.0223 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus granulosus | semaphorin 1A | 0.0164 | 0.0785 | 0.0785 |
Echinococcus granulosus | hexokinase | 0.167 | 1 | 1 |
Echinococcus multilocularis | fibrillin 1 | 0.0364 | 0.2014 | 0.2014 |
Echinococcus multilocularis | neural cadherin | 0.0139 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0228 | 0.1179 | 0.1179 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Brugia malayi | EGF-like domain containing protein | 0.0139 | 0.0635 | 0.0635 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0195 | 0.0195 |
Onchocerca volvulus | 0.167 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.0785 | 0.0785 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0139 | 0.0635 | 0.0635 |
Brugia malayi | EGF-like domain containing protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0067 | 0.0195 | 0.0195 |
Brugia malayi | EGF-like domain containing protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0067 | 0.0195 | 0.0195 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Echinococcus granulosus | Tolloid protein 1 | 0.0364 | 0.2014 | 0.2014 |
Schistosoma mansoni | notch | 0.0139 | 0.0635 | 0.0635 |
Echinococcus multilocularis | protein jagged 2 | 0.0139 | 0.0635 | 0.0635 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Schistosoma mansoni | camp/cgmp cyclic nucleotide phosphodiesterase | 0.0067 | 0.0192 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.2014 | 0.2014 |
Loa Loa (eye worm) | hexokinase | 0.0517 | 0.2946 | 0.2946 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0364 | 0.2014 | 0.2014 |
Brugia malayi | EGF-like domain containing protein | 0.0139 | 0.0635 | 0.0635 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0036 | 0.0008 | 0.0342 |
Brugia malayi | Trypsin family protein | 0.0067 | 0.0195 | 0.0195 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0139 | 0.0635 | 0.0635 |
Mycobacterium ulcerans | hypothetical protein | 0.0067 | 0.0195 | 0.5 |
Giardia lamblia | High cysteine protein | 0.0139 | 0.0635 | 0.5 |
Loa Loa (eye worm) | notch protein | 0.0139 | 0.0635 | 0.0635 |
Brugia malayi | Delta serrate ligand family protein | 0.0139 | 0.0635 | 0.0635 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0364 | 0.2014 | 0.1944 |
Brugia malayi | Hexokinase family protein | 0.1048 | 0.6193 | 0.6193 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Echinococcus granulosus | hexokinase | 0.167 | 1 | 1 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0067 | 0.0192 | 0.011 |
Treponema pallidum | hexokinase (hxk) | 0.167 | 1 | 0.5 |
Trichomonas vaginalis | cAMP/cGMP cyclic nucleotide phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Schistosoma mansoni | notch | 0.0139 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | sema domain-containing protein | 0.0164 | 0.0785 | 0.0785 |
Echinococcus granulosus | dual 3'5' cyclic AMP and GMP phosphodiesterase | 0.0067 | 0.0192 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0139 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0195 | 0.0195 |
Onchocerca volvulus | 0.0164 | 0.0785 | 0.0602 | |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.0785 | 0.0785 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0195 | 0.0195 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0072 | 0.0223 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.0086 | 0.3872 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0223 | 0.0223 |
Brugia malayi | notch-like transmembrane receptor | 0.0139 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0531 | 0.3033 | 0.3033 |
Toxoplasma gondii | hexokinase | 0.167 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0364 | 0.2014 | 0.2014 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0139 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus multilocularis | protein jagged 1 | 0.0139 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0195 | 0.0195 |
Schistosoma mansoni | notch | 0.0139 | 0.0635 | 0.0635 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0067 | 0.0195 | 0.0195 |
Echinococcus multilocularis | hypothetical protein | 0.0164 | 0.0785 | 0.0785 |
Schistosoma mansoni | septate junction protein | 0.0139 | 0.0635 | 0.0635 |
Brugia malayi | Trypsin family protein | 0.0067 | 0.0195 | 0.0195 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Brugia malayi | Plexin repeat family protein | 0.0392 | 0.2179 | 0.2179 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0195 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0531 | 0.3033 | 0.3033 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0067 | 0.0195 | 0.0195 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0139 | 0.0635 | 0.0635 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0043 | 0.0045 | 0.0045 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0067 | 0.0195 | 0.0195 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0043 | 0.0045 | 0.0045 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.0086 | 0.3872 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0139 | 0.0635 | 0.0635 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0139 | 0.0635 | 0.0635 |
Onchocerca volvulus | 0.1048 | 0.6193 | 0.6118 | |
Echinococcus granulosus | protein jagged 2 | 0.0139 | 0.0635 | 0.0635 |
Brugia malayi | EGF-like domain containing protein | 0.0139 | 0.0635 | 0.0635 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0364 | 0.2014 | 0.2014 |
Echinococcus granulosus | semaphorin 5B | 0.0164 | 0.0785 | 0.0785 |
Loa Loa (eye worm) | Notch2 | 0.0139 | 0.0635 | 0.0635 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0139 | 0.0635 | 0.0635 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus granulosus | fibropellin Ia | 0.0139 | 0.0635 | 0.0635 |
Brugia malayi | Probable exocyst complex component Sec5 | 0.0072 | 0.0223 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0392 | 0.2179 | 0.2179 |
Schistosoma mansoni | hexokinase | 0.167 | 1 | 1 |
Onchocerca volvulus | Slit protein homolog | 0.0139 | 0.0635 | 0.0449 |
Echinococcus granulosus | protein jagged 2 | 0.0139 | 0.0635 | 0.0635 |
Schistosoma mansoni | semaphorin 5-related | 0.0164 | 0.0785 | 0.0785 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0039 | 0.0023 | 0.0023 |
Schistosoma mansoni | calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase | 0.0191 | 0.0951 | 0.0951 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0067 | 0.0192 | 0.8609 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus granulosus | plexin a4 | 0.0463 | 0.2618 | 0.2618 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Brugia malayi | Trypsin family protein | 0.0067 | 0.0195 | 0.0195 |
Brugia malayi | Hexokinase family protein | 0.0517 | 0.2946 | 0.2946 |
Brugia malayi | Hexokinase family protein | 0.167 | 1 | 1 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0364 | 0.2014 | 0.2014 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Schistosoma mansoni | notch | 0.0139 | 0.0635 | 0.0635 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0139 | 0.0635 | 0.0635 |
Leishmania major | hexokinase, putative | 0.167 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1139 | 0.6752 | 0.6752 |
Brugia malayi | Sema domain containing protein | 0.0164 | 0.0785 | 0.0785 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0223 | 1 |
Brugia malayi | Cadherin domain containing protein | 0.0139 | 0.0635 | 0.0635 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Echinococcus granulosus | delta-like protein 1 | 0.0139 | 0.0635 | 0.0635 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0191 | 0.0951 | 0.0951 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Echinococcus granulosus | notch | 0.0139 | 0.0635 | 0.0635 |
Echinococcus granulosus | hexokinase type 2 | 0.167 | 1 | 1 |
Brugia malayi | Muscle positioning protein 4 | 0.0139 | 0.0635 | 0.0635 |
Onchocerca volvulus | 0.0139 | 0.0635 | 0.0449 | |
Onchocerca volvulus | 0.167 | 1 | 1 | |
Plasmodium vivax | hexokinase, putative | 0.167 | 1 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0223 | 0.0223 |
Entamoeba histolytica | tyrosin kinase, putative | 0.0091 | 0.034 | 0.012 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Brugia malayi | hypothetical protein | 0.0164 | 0.0785 | 0.0785 |
Brugia malayi | hypothetical protein | 0.0164 | 0.0785 | 0.0785 |
Echinococcus multilocularis | Mastin | 0.0067 | 0.0195 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.0785 | 0.0785 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus multilocularis | enteropeptidase | 0.0067 | 0.0195 | 0.0195 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0139 | 0.0635 | 0.0635 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Onchocerca volvulus | 0.0139 | 0.0635 | 0.0449 | |
Trypanosoma brucei | hexokinase, putative | 0.167 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Trypanosoma cruzi | hexokinase, putative | 0.167 | 1 | 1 |
Schistosoma mansoni | plexin | 0.0228 | 0.1179 | 0.1179 |
Echinococcus multilocularis | semaphorin 5B | 0.0164 | 0.0785 | 0.0785 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Echinococcus multilocularis | laminin | 0.0364 | 0.2014 | 0.2014 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0.0086 | 0.3872 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0364 | 0.2014 | 0.2014 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0223 | 0.0223 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Brugia malayi | plexin A | 0.0463 | 0.2618 | 0.2618 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0067 | 0.0195 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus multilocularis | plexin a4 | 0.0463 | 0.2618 | 0.2618 |
Brugia malayi | EGF-like domain containing protein | 0.0139 | 0.0635 | 0.0635 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative | 0.0191 | 0.0951 | 0.0951 |
Loa Loa (eye worm) | hexokinase type II | 0.167 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0223 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0223 | 1 |
Brugia malayi | Trypsin family protein | 0.0067 | 0.0195 | 0.0195 |
Trichomonas vaginalis | cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative | 0.0049 | 0.0083 | 0.3698 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0039 | 0.0023 | 0.0023 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0072 | 0.0223 | 1 |
Echinococcus multilocularis | hexokinase | 0.167 | 1 | 1 |
Loa Loa (eye worm) | plexin A | 0.0463 | 0.2618 | 0.2618 |
Echinococcus granulosus | laminin | 0.0364 | 0.2014 | 0.2014 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0635 | 0.0635 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0067 | 0.0195 | 0.0195 |
Entamoeba histolytica | hexokinase 2 | 0.167 | 1 | 1 |
Echinococcus granulosus | neural cadherin | 0.0139 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.2014 | 0.2014 |
Loa Loa (eye worm) | hexokinase | 0.167 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0195 | 0.0195 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0067 | 0.0192 | 0.8609 |
Echinococcus granulosus | hexokinase | 0.167 | 1 | 1 |
Trypanosoma brucei | hexokinase | 0.167 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.0785 | 0.0785 |
Echinococcus multilocularis | hexokinase | 0.167 | 1 | 1 |
Echinococcus multilocularis | hexokinase type 2 | 0.167 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0195 | 0.0195 |
Brugia malayi | Sema domain containing protein | 0.0164 | 0.0785 | 0.0785 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Relative protection (binding) | = 0.7 | Protective effect tested by the inhibition of Staphylococcus aureus beta-lactamase relative to clavulanic acid | ChEMBL. | No reference |
Relative protection (binding) | = 1.5 | Protective effect of compound was tested by the inhibition of Proteus vulgaris beta-lactamase relative to clavulanic acid as 1 | ChEMBL. | No reference |
Relative protection (binding) | = 0.7 | Protective effect tested by the inhibition of Staphylococcus aureus beta-lactamase relative to clavulanic acid | ChEMBL. | No reference |
Relative protection (binding) | = 1.5 | Protective effect of compound was tested by the inhibition of Proteus vulgaris beta-lactamase relative to clavulanic acid as 1 | ChEMBL. | No reference |
T1/2 (ADMET) | = 6.8 hr | T1/2 (phosphate buffer pH 7.0 @ 28 degree C) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.