Detailed information for compound 1154975

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 464.934 | Formula: C27H23ClF2N2O
  • H donors: 0 H acceptors: 1 LogP: 6.06 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)n1c2CCN(Cc2c2c1ccc(c2)F)CCCC(=O)c1ccc(cc1)Cl
  • InChi: 1S/C27H23ClF2N2O/c28-19-5-3-18(4-6-19)27(33)2-1-14-31-15-13-26-24(17-31)23-16-21(30)9-12-25(23)32(26)22-10-7-20(29)8-11-22/h3-12,16H,1-2,13-15,17H2
  • InChiKey: IKYKOBLBXKWLGT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus FTZ F1 alpha 0.0033 0.0119 0.0194
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Onchocerca volvulus 0.0106 0.0531 0.1801
Toxoplasma gondii kringle domain-containing protein 0.0018 0.0033 0.1141
Brugia malayi celfurPC protein 0.0848 0.4732 0.7698
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0014
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.002 0.0033
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Brugia malayi nuclear hormone receptor 0.0033 0.0119 0.0194
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0029 0.0096 0.2572
Leishmania major heat shock protein, putative 0.0015 0.0017 0.0447
Trichomonas vaginalis conserved hypothetical protein 0.025 0.1347 0.4109
Loa Loa (eye worm) hypothetical protein 0.0035 0.0132 0.0214
Loa Loa (eye worm) hypothetical protein 0.1099 0.6146 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0033 0.0119 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0033 0.0119 0.0194
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0033
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0033 0.0054
Trypanosoma cruzi heat shock protein 90, putative 0.0036 0.0138 0.3396
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0015 0.0017 0.0145
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0152 0.0465
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0027 0.0082 0.0047
Brugia malayi isocitrate dehydrogenase 0.0035 0.0128 0.0209
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.0041 0.0164 0.41
Trypanosoma brucei heat shock protein, putative 0.0036 0.0138 0.3692
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0033
Schistosoma mansoni cpg binding protein 0.0032 0.0114 0.0186
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Brugia malayi steroid hormone receptor 0.0033 0.0119 0.0194
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0079 0.0379 0.0379
Schistosoma mansoni hypothetical protein 0.0089 0.0438 0.0712
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0213 0.0213
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0033 0.0119 0.0194
Loa Loa (eye worm) hypothetical protein 0.0269 0.1453 0.2365
Schistosoma mansoni hypothetical protein 0.0106 0.0531 0.0864
Giardia lamblia Furin precursor putative serine protease 0.0298 0.1616 1
Brugia malayi Isocitrate dehydrogenase 0.0035 0.0128 0.0209
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.0112 0.0182
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0081 0.0388 0.0632
Brugia malayi exodeoxyribonuclease III family protein 0.0027 0.0082 0.0134
Schistosoma mansoni integrin alpha 0.0151 0.0787 0.128
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Toxoplasma gondii subtilisin SUB6 0.0055 0.0245 0.8435
Brugia malayi ecdysone receptor 0.0016 0.002 0.0033
Brugia malayi Fli-1 protein 0.0245 0.1316 0.2142
Echinococcus granulosus Protein patched homolog 1 0.0093 0.0457 0.0743
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0035 0.0128 0.0112
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0079 0.0379 0.0617
Plasmodium vivax heat shock protein 90, putative 0.0015 0.0017 0.0578
Schistosoma mansoni ets-related 0.0245 0.1316 0.2142
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0353 0.1928 0.5883
Trichomonas vaginalis heat shock protein, putative 0.0015 0.0017 0.0051
Brugia malayi Integrin alpha pat-2 precursor 0.0151 0.0787 0.128
Toxoplasma gondii LsmAD domain-containing protein 0.0041 0.0164 0.5638
Loa Loa (eye worm) hypothetical protein 0.0069 0.0322 0.0524
Schistosoma mansoni hypothetical protein 0.005 0.0213 0.0347
Trichomonas vaginalis conserved hypothetical protein 0.025 0.1347 0.4109
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0055 0.0245 0.6366
Loa Loa (eye worm) patched family protein 0.0013 0.0006 0.001
Trichomonas vaginalis conserved hypothetical protein 0.025 0.1347 0.4109
Loa Loa (eye worm) hypothetical protein 0.0555 0.307 0.4994
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.021 0.0342
Echinococcus multilocularis 0.0848 0.4732 0.4732
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0055 0.0245 0.0258
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0047 0.0196 0.522
Trichomonas vaginalis conserved hypothetical protein 0.025 0.1347 0.4109
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Entamoeba histolytica hypothetical protein 0.0079 0.0379 0.3282
Trichomonas vaginalis conserved hypothetical protein 0.025 0.1347 0.4109
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0014
Loa Loa (eye worm) nuclear receptor NHR-67 0.0016 0.002 0.0033
Schistosoma mansoni hypothetical protein 0.0165 0.0866 0.141
Trichomonas vaginalis ap endonuclease, putative 0.0027 0.0082 0.0251
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Brugia malayi MH1 domain containing protein 0.0018 0.0033 0.0054
Echinococcus multilocularis heat shock protein 90 0.0029 0.0096 0.0096
Echinococcus granulosus muscleblind protein 0.016 0.0839 0.1366
Schistosoma mansoni hypothetical protein 0.005 0.0213 0.0347
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0016 0.002 0.0033
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Brugia malayi Steroid receptor seven-up type 2 0.013 0.0665 0.1082
Echinococcus granulosus laminin 0.0014 0.0009 0.0014
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0033
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0223 0.0679
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0054
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Giardia lamblia Heat shock protein HSP 90-alpha 0.0029 0.0096 0.0093
Toxoplasma gondii heat shock protein 75, putative 0.0015 0.0017 0.0578
Trichomonas vaginalis CAMK family protein kinase 0.0078 0.0375 0.1144
Schistosoma mansoni hypothetical protein 0.0089 0.0438 0.0712
Toxoplasma gondii subtilisin SUB2 0.0055 0.0245 0.8435
Trichomonas vaginalis CAMK family protein kinase 0.0078 0.0375 0.1144
Loa Loa (eye worm) Smad1 0.0018 0.0033 0.0054
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0033 0.0054
Schistosoma mansoni patched 1 0.0093 0.0457 0.0743
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.0112 0.0182
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0033 0.0119 0.0194
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Brugia malayi Kringle domain containing protein 0.0018 0.0033 0.0054
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0055 0.0245 1
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0055 0.0245 0.0245
Trichomonas vaginalis conserved hypothetical protein 0.025 0.1347 0.4109
Brugia malayi hypothetical protein 0.0013 0.0006 0.001
Brugia malayi nuclear receptor NHR-67 0.0016 0.002 0.0033
Echinococcus granulosus neuropeptide s receptor 0.0525 0.2903 0.4723
Echinococcus granulosus nuclear receptor nhr 48 0.0016 0.002 0.0033
Echinococcus multilocularis snurportin 1 0.0676 0.3754 0.3754
Toxoplasma gondii patched family protein 0.0013 0.0006 0.0221
Schistosoma mansoni coup transcription factor 0.0033 0.0119 0.0194
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0119 0.0194
Echinococcus multilocularis importin subunit beta 1 0.0063 0.029 0.029
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0029 0.0096 0.0072
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0033
Loa Loa (eye worm) patched family protein 0.0013 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0031 0.005
Echinococcus granulosus importin subunit beta 1 0.0063 0.029 0.0472
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0657
Giardia lamblia Heat shock protein HSP 90-alpha 0.0036 0.0138 0.0367
Loa Loa (eye worm) steroid hormone receptor 0.0033 0.0119 0.0194
Schistosoma mansoni endoplasmin 0.0036 0.0138 0.0225
Loa Loa (eye worm) hypothetical protein 0.0216 0.1155 0.1879
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0103 0.0514 0.1567
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0059 0.0267 0.0435
Trichomonas vaginalis heat shock protein, putative 0.0022 0.0059 0.0179
Schistosoma mansoni nuclear receptor 0.0016 0.002 0.0033
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Brugia malayi protein C24B5.3 0.0013 0.0006 0.001
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0119 0.0194
Schistosoma mansoni integrin alpha-ps 0.0068 0.0315 0.0513
Echinococcus multilocularis Mastin 0.0049 0.0212 0.0212
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0119 0.0119
Brugia malayi nuclear hormone receptor family member odr-7 0.0016 0.002 0.0033
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0083 0.0135
Toxoplasma gondii isocitrate dehydrogenase 0.0035 0.0128 0.4425
Schistosoma mansoni smad 0.0018 0.0033 0.0054
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0014 0.0009 0.0014
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0014 0.0009 0.0014
Plasmodium vivax patched family protein, putative 0.0013 0.0006 0.0221
Echinococcus multilocularis X box binding protein 1 0.0323 0.176 0.176
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Brugia malayi hypothetical protein 0.0041 0.0164 0.0266
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0027 0.0082 0.2192
Echinococcus granulosus neuropeptide receptor A26 0.0525 0.2903 0.4723
Toxoplasma gondii calcium binding egf domain-containing protein 0.0014 0.0009 0.0301
Trichomonas vaginalis endoplasmin, putative 0.0022 0.0059 0.0179
Toxoplasma gondii heat shock protein 90, putative 0.0036 0.0138 0.477
Loa Loa (eye worm) TK/ROR protein kinase 0.0018 0.0033 0.0054
Giardia lamblia High cysteine membrane protein Group 2 0.0286 0.1551 0.9576
Brugia malayi Calcitonin receptor-like protein seb-1 0.0157 0.0821 0.1336
Echinococcus granulosus Mastin 0.0049 0.0212 0.0345
Schistosoma mansoni ran 0.0047 0.0196 0.0319
Loa Loa (eye worm) hypothetical protein 0.0017 0.0031 0.005
Echinococcus multilocularis heat shock protein 0.0036 0.0138 0.0138
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0031 0.005
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.0128 0.3425
Brugia malayi hypothetical protein 0.0519 0.2868 0.4666
Brugia malayi orphan nuclear receptor NR2E1 0.0016 0.002 0.0033
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0033 0.0119 0.0194
Echinococcus multilocularis musashi 0.0059 0.0267 0.0267
Loa Loa (eye worm) endoprotease bli-4 0.1099 0.6146 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0035 0.0128 0.4425
Loa Loa (eye worm) hypothetical protein 0.0033 0.0119 0.0194
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0027 0.0082 0.0134
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.1099 0.6146 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0119 0.0603 0.0982
Brugia malayi hypothetical protein 0.0016 0.002 0.0033
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0083 0.0719
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.0119 0.0194
Toxoplasma gondii isocitrate dehydrogenase 0.0035 0.0128 0.4425
Trypanosoma cruzi importin beta-1 subunit, putative 0.0051 0.0223 0.5744
Onchocerca volvulus 0.0048 0.0201 0.0669
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0047 0.0196 0.6744
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0045 0.0008
Brugia malayi conserved hypotetical protein 0.0016 0.002 0.0033
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0027 0.0082 0.0712
Brugia malayi hypothetical protein 0.0079 0.0379 0.0617
Onchocerca volvulus 0.0528 0.292 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0035 0.0128 0.4425
Brugia malayi follicle stimulating hormone receptor 0.0256 0.1381 0.2247
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0055 0.0245 0.0251
Schistosoma mansoni furin-1 (S08 family) 0.0562 0.3113 0.5065
Echinococcus multilocularis muscleblind protein 0.016 0.0839 0.0839
Echinococcus granulosus epidermal growth factor receptor 0.0182 0.0963 0.1566
Plasmodium falciparum subtilisin-like protease 3 0.0055 0.0245 0.8435
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Brugia malayi hypothetical protein 0.0269 0.1453 0.2365
Echinococcus granulosus GTP binding nuclear protein Ran 0.0047 0.0196 0.0319
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0033 0.0119 0.0194
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0047 0.0196 0.0319
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0014 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0031 0.005
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.021 0.0342
Brugia malayi Subtilase family protein 0.0055 0.0245 0.0398
Trypanosoma cruzi subtilisin peptidase 0.0055 0.0245 0.6366
Trypanosoma cruzi heat shock protein 85, putative 0.0036 0.0138 0.3396
Onchocerca volvulus 0.0016 0.002 0.0048
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0083 0.0048
Entamoeba histolytica heat shock protein 90, putative 0.0036 0.0138 0.1199
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Toxoplasma gondii HEAT repeat-containing protein 0.0063 0.029 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0027 0.0082 0.2832
Echinococcus multilocularis integrin alpha ps 0.0032 0.0116 0.0116
Brugia malayi nuclear receptor NHR-88 0.0033 0.0119 0.0194
Echinococcus granulosus lamin dm0 0.0059 0.0267 0.0435
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0055 0.0245 0.0398
Plasmodium falciparum heat shock protein 90, putative 0.0015 0.0017 0.0578
Trypanosoma brucei heat shock protein 84, putative 0.0015 0.0017 0.0447
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0033 0.0119 0.0194
Giardia lamblia Grp94/Hsp90 0.0029 0.0096 0.0093
Loa Loa (eye worm) hypothetical protein 0.0032 0.0116 0.0189
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0031 0.005
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0096 0.0294
Loa Loa (eye worm) hypothetical protein 0.0029 0.0094 0.0153
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0083 0.0048
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0083 0.0135
Brugia malayi hypothetical protein 0.0013 0.0006 0.001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.0119 0.0194
Loa Loa (eye worm) transcription factor SMAD2 0.0262 0.1415 0.2301
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Echinococcus multilocularis Smad4 0.0018 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0033
Schistosoma mansoni kinase 0.004 0.0158 0.0257
Brugia malayi MH1 domain containing protein 0.0018 0.0033 0.0054
Echinococcus multilocularis lamin dm0 0.0059 0.0267 0.0267
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0033 0.0119 0.0194
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0033 0.0119 0.0194
Loa Loa (eye worm) hypothetical protein 0.0519 0.2868 0.4666
Plasmodium vivax heat shock protein 86, putative 0.0036 0.0138 0.477
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.021 0.0342
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0353 0.1928 0.5883
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0027 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0216 0.1155 1
Echinococcus multilocularis muscleblind protein 1 0.016 0.0839 0.0839
Echinococcus multilocularis Niemann Pick C1 protein 0.0216 0.1155 0.1155
Onchocerca volvulus 0.014 0.0726 0.247
Trypanosoma brucei heat shock protein, putative 0.0036 0.0138 0.3692
Plasmodium vivax subtilisin-like protease 1 0.0055 0.0245 0.8435
Echinococcus granulosus integrin alpha ps 0.0032 0.0116 0.0189
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0016 0.002 0.002
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0047 0.0196 0.6744
Echinococcus granulosus lamin 0.0059 0.0267 0.0435
Trypanosoma brucei polo-like protein kinase 0.0078 0.0375 1
Echinococcus granulosus snurportin 1 0.0676 0.3754 0.6108
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Loa Loa (eye worm) endoplasmin 0.0036 0.0138 0.0225
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0031 0.005
Trichomonas vaginalis conserved hypothetical protein 0.025 0.1347 0.4109
Echinococcus multilocularis smad 0.0018 0.0033 0.0033
Onchocerca volvulus 0.0033 0.0119 0.0387
Loa Loa (eye worm) heat shock protein 90 0.0036 0.0138 0.0225
Echinococcus granulosus X box binding protein 1 0.0323 0.176 0.2863
Leishmania major hypothetical protein, conserved 0.0041 0.0164 0.4364
Schistosoma mansoni smad1 5 8 and 0.0018 0.0033 0.0054
Mycobacterium ulcerans arylamine N-acetyltransferase Nat 0.1431 0.8025 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Trypanosoma brucei subtilisin peptidase 0.0055 0.0245 0.6529
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0213 0.0347
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0073
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0055 0.0245 0.6366
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0033
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.021 0.0342
Trypanosoma cruzi PAB1-binding protein , putative 0.0041 0.0164 0.41
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0729 0.1187
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0027 0.0082 0.1826
Brugia malayi RNA, U transporter 1 0.018 0.095 0.1546
Schistosoma mansoni cpg binding protein 0.0034 0.0125 0.0203
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0119 0.0194
Schistosoma mansoni hypothetical protein 0.0676 0.3754 0.6108
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0014
Schistosoma mansoni nuclear receptor nhr-48 0.0016 0.002 0.0033
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Echinococcus multilocularis Furin 1 0.0353 0.1928 0.1928
Brugia malayi Patched related family protein 10 0.0013 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.016 0.0839 0.1366
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0591 0.3278 1
Plasmodium vivax subtilisin-like serine protease, putative 0.0055 0.0245 0.8435
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0033 0.0119 0.0194
Loa Loa (eye worm) hypothetical protein 0.0269 0.1453 0.2365
Plasmodium falciparum lipid/sterol:H+ symporter 0.0013 0.0006 0.0221
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Brugia malayi Nuclear hormone receptor E75 0.0016 0.002 0.0033
Brugia malayi Importin beta-1 subunit 0.0063 0.029 0.0472
Trichomonas vaginalis importin beta-1, putative 0.0051 0.0223 0.0679
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0093 0.0457 0.0743
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Schistosoma mansoni hypothetical protein 0.025 0.1347 0.2191
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0353 0.1928 0.5883
Brugia malayi Muscleblind-like protein 0.016 0.0839 0.1366
Trichomonas vaginalis CAMK family protein kinase 0.0078 0.0375 0.1144
Schistosoma mansoni hypothetical protein 0.0032 0.0116 0.0189
Schistosoma mansoni ran 0.0047 0.0196 0.0319
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0033 0.0119 0.0194
Brugia malayi Ets-domain containing protein 0.0081 0.0388 0.0632
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Echinococcus granulosus enteropeptidase 0.0049 0.0212 0.0345
Echinococcus granulosus geminin 0.0165 0.0866 0.141
Brugia malayi Protein kinase domain containing protein 0.0437 0.2405 0.3914
Loa Loa (eye worm) hypothetical protein 0.0114 0.0577 0.0938
Echinococcus granulosus heat shock protein 90 0.0036 0.0138 0.0225
Echinococcus multilocularis lamin 0.0059 0.0267 0.0267
Loa Loa (eye worm) subtilase 0.0055 0.0245 0.0398
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0353 0.1928 0.5883
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Toxoplasma gondii subtilisin SUB5 0.0055 0.0245 0.8435
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0033 0.0119 0.0194
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0078 0.0375 0.0375
Loa Loa (eye worm) patched family protein 0.0013 0.0006 0.001
Echinococcus granulosus rho-associated protein kinase 1 0.0141 0.0729 0.1187
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0027 0.0082 0.2192
Brugia malayi nuclear hormone receptor 0.0016 0.002 0.0033
Schistosoma mansoni hypothetical protein 0.0079 0.0379 0.0617
Trichomonas vaginalis conserved hypothetical protein 0.025 0.1347 0.4109
Trichomonas vaginalis ap endonuclease, putative 0.0027 0.0082 0.0251
Schistosoma mansoni hypothetical protein 0.0018 0.0033 0.0054
Loa Loa (eye worm) hypothetical protein 0.0203 0.108 0.1757
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0676 0.3754 0.6108
Echinococcus multilocularis neuroendocrine convertase 2 0.086 0.4797 0.4797
Loa Loa (eye worm) integrin alpha pat-2 0.0233 0.125 0.2033
Echinococcus multilocularis cpg binding protein 0.0034 0.0125 0.0125
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0213 0.0347
Echinococcus granulosus heat shock protein 0.0036 0.0138 0.0225
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0103 0.0514 0.0836
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Brugia malayi Intermediate filament tail domain containing protein 0.0059 0.0267 0.0435
Schistosoma mansoni heat shock protein 0.0015 0.0017 0.0027
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0083 0.0719
Echinococcus multilocularis FTZ F1 alpha 0.0033 0.0119 0.0119
Loa Loa (eye worm) pax transcription factor protein 2 0.0528 0.292 0.4751
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0055 0.0245 0.0251
Loa Loa (eye worm) hypothetical protein 0.016 0.0839 0.1366
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Echinococcus granulosus heat shock protein 90 0.0029 0.0096 0.0157
Schistosoma mansoni smad1 5 8 and 0.0018 0.0033 0.0054
Plasmodium falciparum ataxin-2 like protein, putative 0.0041 0.0164 0.5638
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0353 0.1928 0.3137
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Trichomonas vaginalis conserved hypothetical protein 0.025 0.1347 0.4109
Echinococcus multilocularis ecdysone induced protein 78C 0.0033 0.0119 0.0119
Trichomonas vaginalis CAMK family protein kinase 0.0078 0.0375 0.1144
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0031 0.0031
Trypanosoma brucei heat shock protein, putative 0.0036 0.0138 0.3692
Echinococcus multilocularis Tolloid protein 1 0.0014 0.0009 0.0009
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Loa Loa (eye worm) hypothetical protein 0.0027 0.0083 0.0135
Mycobacterium tuberculosis Arylamine N-acetyltransferase Nat (arylamine acetylase) 0.1431 0.8025 1
Schistosoma mansoni thyroid hormone receptor 0.0033 0.0119 0.0194
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0033 0.0054
Echinococcus multilocularis neuropeptide s receptor 0.0525 0.2903 0.2903
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0018 0.0033 0.1141
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0213 0.0347
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Toxoplasma gondii subtilisin SUB1 0.0055 0.0245 0.8435
Trypanosoma cruzi heat shock protein 90, putative 0.0029 0.0096 0.2225
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0033
Brugia malayi neuroendocrine convertase 1 precursor 0.0989 0.5526 0.899
Schistosoma mansoni lamin 0.0059 0.0267 0.0435
Brugia malayi protein C24B5.3 0.0013 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0033 0.0119 0.0194
Trichomonas vaginalis CAMK family protein kinase 0.0078 0.0375 0.1144
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0055 0.0245 0.0258
Plasmodium falciparum heat shock protein 90, putative 0.0015 0.0017 0.0578
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0083 0.0135
Brugia malayi intermediate filament protein 0.0059 0.0267 0.0435
Schistosoma mansoni cpg binding protein 0.0034 0.0125 0.0203
Toxoplasma gondii hypothetical protein 0.0013 0.0006 0.0221
Echinococcus multilocularis integrin alpha 3 0.0116 0.0587 0.0587
Onchocerca volvulus 0.0016 0.002 0.0048
Leishmania major hypothetical protein, conserved 0.0018 0.0033 0.0883
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0055 0.0245 0.0258
Mycobacterium ulcerans hypothetical protein 0.0027 0.0083 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0245 0.0747
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.021 0.0342
Plasmodium vivax importin-beta 2, putative 0.0063 0.029 1
Trypanosoma cruzi heat shock protein 85, putative 0.0036 0.0138 0.3396
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.021 0.0342
Loa Loa (eye worm) hypothetical protein 0.0027 0.0088 0.0143
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0027 0.0082 0.0134
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0157 0.0821 0.1336
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0055 0.0245 0.0251
Schistosoma mansoni endoplasmin 0.0036 0.0138 0.0225
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0049 0.0212 0.0345
Loa Loa (eye worm) hypothetical protein 0.0027 0.0083 0.0135
Entamoeba histolytica serine/threonine protein kinase, putative 0.0078 0.0375 0.3248
Trypanosoma cruzi polo-like protein kinase, putative 0.0078 0.0375 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0033 0.0119 0.0119
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0016 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0033
Echinococcus multilocularis GA binding protein alpha chain 0.0081 0.0388 0.0388
Schistosoma mansoni gabp alpha 0.0081 0.0388 0.0632
Echinococcus multilocularis laminin 0.0014 0.0009 0.0009
Echinococcus multilocularis survival motor neuron protein 1 0.0519 0.2868 0.2868
Toxoplasma gondii heat shock protein HSP90 0.0036 0.0138 0.477
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Schistosoma mansoni zinc finger protein 0.0016 0.002 0.0033
Echinococcus multilocularis neuropeptide receptor A26 0.0525 0.2903 0.2903
Brugia malayi Protein kinase domain containing protein 0.0018 0.0033 0.0054
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.0128 0.0128
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0096 0.0294
Loa Loa (eye worm) hypothetical protein 0.0093 0.0457 0.0743
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0027 0.0082 0.0054
Entamoeba histolytica hypothetical protein 0.0079 0.0379 0.3282
Brugia malayi nuclear receptor RXR 0.0017 0.0031 0.005
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.013 0.0665 0.1082
Echinococcus granulosus Nuclear hormone receptor HR96 0.0016 0.002 0.0033
Trypanosoma brucei heat shock protein, putative 0.0036 0.0138 0.3692
Echinococcus granulosus glycoprotein Antigen 5 0.0049 0.0212 0.0345
Loa Loa (eye worm) heat shock protein 75 0.0015 0.0017 0.0027
Brugia malayi heat shock protein 90 0.0036 0.0138 0.0225
Echinococcus multilocularis integrin alpha ps 0.0068 0.0315 0.0315
Echinococcus granulosus expressed conserved protein 0.0203 0.1081 0.1758
Brugia malayi Furin-like cysteine rich region family protein 0.0182 0.0963 0.1566
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0033
Brugia malayi Endoplasmin precursor 0.0036 0.0138 0.0225
Echinococcus multilocularis tissue type plasminogen activator 0.0018 0.0033 0.0033
Plasmodium vivax heat shock protein, putative 0.0015 0.0017 0.0578
Schistosoma mansoni hypothetical protein 0.005 0.0213 0.0347
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Schistosoma mansoni smad1 5 8 and 0.0018 0.0033 0.0054
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0047 0.0196 0.0196
Echinococcus multilocularis nuclear receptor nhr 48 0.0016 0.002 0.002
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Echinococcus granulosus tissue type plasminogen activator 0.0018 0.0033 0.0054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0033 0.0119 0.0194
Schistosoma mansoni hypothetical protein 0.005 0.0213 0.0347
Schistosoma mansoni hypothetical protein 0.0323 0.176 0.2863
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0055 0.0245 0.0398
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0083 0.2214
Loa Loa (eye worm) fli-1 protein 0.0245 0.1316 0.2142
Toxoplasma gondii subtilisin SUB11 0.0055 0.0245 0.8435
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0033 0.0119 0.0194
Plasmodium falciparum subtilisin-like protease 1 0.0055 0.0245 0.8435
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Toxoplasma gondii subtilisin SUB7 0.0055 0.0245 0.8435
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.002 0.0048
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0083 0.2214
Echinococcus granulosus dnaJ subfamily B 0.0459 0.2527 0.4111
Loa Loa (eye worm) TK/EGFR protein kinase 0.0182 0.0963 0.1566
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0157 0.0821 0.1336
Schistosoma mansoni intermediate filament proteins 0.0059 0.0267 0.0435
Brugia malayi Patched related family protein 4 0.0013 0.0006 0.001
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.013 0.0665 0.0665
Toxoplasma gondii calcium binding egf domain-containing protein 0.0014 0.0009 0.0301
Onchocerca volvulus 0.0018 0.0033 0.0092
Toxoplasma gondii subtilisin SUB10 0.0055 0.0245 0.8435
Loa Loa (eye worm) hypothetical protein 0.0033 0.0119 0.0194
Echinococcus multilocularis dnaJ subfamily B 0.0459 0.2527 0.2527
Echinococcus multilocularis Niemann Pick C1 protein 0.0309 0.1679 0.1679
Trichomonas vaginalis heat shock protein, putative 0.0036 0.0138 0.0422
Echinococcus multilocularis rho associated protein kinase 0.0141 0.0729 0.0729
Brugia malayi nuclear receptor RXR 0.0016 0.002 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.025 0.1347 0.4109
Schistosoma mansoni nuclear receptor 0.0016 0.002 0.0033
Echinococcus multilocularis isocitrate dehydrogenase 0.0035 0.0128 0.0128
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0047 0.0196 0.0741
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0083 0.0048
Schistosoma mansoni heat shock protein 0.0036 0.0138 0.0225
Trypanosoma brucei heat shock protein 90, putative 0.0036 0.0138 0.3692
Loa Loa (eye worm) hypothetical protein 0.0033 0.0119 0.0194
Echinococcus multilocularis fibrillin 1 0.0014 0.0013 0.0013
Loa Loa (eye worm) isocitrate dehydrogenase 0.0035 0.0128 0.0209
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0055 0.0245 0.0398
Echinococcus granulosus integrin alpha ps 0.0068 0.0315 0.0513
Echinococcus granulosus GA binding protein alpha chain 0.0081 0.0388 0.0632
Echinococcus multilocularis GPCR, family 2 0.005 0.0213 0.0213
Schistosoma mansoni serine/threonine protein kinase 0.0078 0.0375 0.061
Onchocerca volvulus Protein ultraspiracle homolog 0.0033 0.0119 0.0387
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Echinococcus multilocularis heat shock protein 90 0.0036 0.0138 0.0138
Toxoplasma gondii subtilisin SUB4 0.0055 0.0245 0.8435
Loa Loa (eye worm) hypothetical protein 0.0041 0.0164 0.0266
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0083 0.0048
Brugia malayi nuclear hormone receptor family member nhr-6 0.0016 0.002 0.0033
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0014 0.0009 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0033 0.0119 0.0194
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Schistosoma mansoni hypothetical protein 0.0107 0.054 0.0878
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0035 0.0128 0.0128
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0027 0.0082 0.2832
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0035 0.0128 0.3117
Brugia malayi MH2 domain containing protein 0.0262 0.1415 0.2301
Brugia malayi Pax transcription factor protein 2 0.0528 0.292 0.4751
Echinococcus granulosus Tolloid protein 1 0.0014 0.0009 0.0014
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0245 0.0747
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0055 0.0245 0.6366
Toxoplasma gondii patched family protein 0.0013 0.0006 0.0221
Brugia malayi ecdysteroid receptor 0.0033 0.0119 0.0194
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Schistosoma mansoni hypothetical protein 0.0089 0.0438 0.0712
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.025 0.1347 0.4109
Echinococcus granulosus Smad4 0.0018 0.0033 0.0054
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0033
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.0128 0.0128
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0083 0.0055
Echinococcus granulosus sterol regulatory element binding protein 0.0093 0.0457 0.0743
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.002 0.002
Onchocerca volvulus 0.0059 0.0267 0.0895
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0033 0.0457
Trichomonas vaginalis ran, putative 0.0047 0.0196 0.0597
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0256 0.1381 0.2247
Schistosoma mansoni Smad4 0.0018 0.0033 0.0054
Echinococcus multilocularis membrane bound transcription factor site 1 0.0055 0.0245 0.0245
Brugia malayi hypothetical protein 0.0017 0.0031 0.005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0033 0.0119 0.0194
Trypanosoma brucei heat shock protein 90, putative 0.0036 0.0138 0.3692
Trichomonas vaginalis conserved hypothetical protein 0.0093 0.0457 0.1394
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0013 0.0003 0.0083
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0055 0.0245 0.6529
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0298 0.1616 0.4929
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0213 0.0213
Echinococcus granulosus cpg binding protein 0.0034 0.0125 0.0203
Loa Loa (eye worm) proprotein convertase 2 0.0353 0.1928 0.3137
Echinococcus multilocularis protein dispatched 1 0.0106 0.0531 0.0531
Onchocerca volvulus 0.0032 0.0114 0.0371
Brugia malayi CHE-14 protein 0.0093 0.0457 0.0743
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Onchocerca volvulus 0.0055 0.0245 0.0818
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0018 0.0036 0.0059
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0015 0.0017 0.0036
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0035 0.0128 0.0209
Toxoplasma gondii exonuclease III APE 0.0027 0.0082 0.2832
Schistosoma mansoni steroid hormone receptor ad4bp 0.0033 0.0119 0.0194
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.0128 0.3425
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Schistosoma mansoni ap endonuclease 0.0027 0.0082 0.0134
Entamoeba histolytica heat shock protein 90, putative 0.0036 0.0138 0.1199
Echinococcus granulosus intermediate filament protein 0.0059 0.0267 0.0435
Plasmodium falciparum subtilisin-like protease 2 0.0055 0.0245 0.8435
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0016 0.002 0.0048
Leishmania major GTP-binding protein, putative 0.0047 0.0196 0.522
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0035 0.0128 0.0209
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0083 0.0719
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0016 0.002 0.0033
Echinococcus granulosus neuroendocrine convertase 2 0.086 0.4797 0.7804
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0047 0.0196 0.4996
Loa Loa (eye worm) hypothetical protein 0.0114 0.0579 0.0942
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.021 0.021
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0096 0.0294
Plasmodium vivax endoplasmin, putative 0.0036 0.0138 0.477
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0045 0.1547
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0033
Entamoeba histolytica hypothetical protein 0.0051 0.0223 0.1928
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0029 0.0096 1
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0437 0.2405 0.3914
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0047 0.0196 0.0319
Brugia malayi Patched related family protein 12 0.0013 0.0006 0.001
Loa Loa (eye worm) patched family protein 0.0013 0.0006 0.001
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0033 0.0054
Trypanosoma cruzi Heat shock protein 83, putative 0.0036 0.0138 0.3396
Leishmania major importin beta-1 subunit, putative 0.0051 0.0223 0.5935
Echinococcus multilocularis sterol regulatory element binding protein 0.0093 0.0457 0.0457
Brugia malayi Calcium binding EGF domain containing protein 0.0014 0.0009 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0078 0.0375 0.1144
Echinococcus granulosus membrane bound transcription factor site 1 0.0055 0.0245 0.0398
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0201 0.0613
Onchocerca volvulus Bile acid receptor homolog 0.0033 0.0119 0.0387
Schistosoma mansoni importin beta-1 0.0063 0.029 0.0472
Schistosoma mansoni survival motor neuron protein 0.0106 0.0531 0.0864
Plasmodium falciparum endoplasmin, putative 0.0022 0.0059 0.2024
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.0119 0.0194
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0083 0.2214
Schistosoma mansoni hypothetical protein 0.0165 0.0866 0.141
Trypanosoma brucei importin beta-1 subunit, putative 0.0063 0.029 0.774
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0045 0.1547
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0591 0.3278 0.5333
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0083 0.0048
Schistosoma mansoni site-1 peptidase (S08 family) 0.0055 0.0245 0.0398
Brugia malayi hypothetical protein 0.0017 0.0031 0.005
Schistosoma mansoni egf-like domain protein 0.0014 0.0009 0.0014
Mycobacterium leprae Possible secreted protease 0.0055 0.0245 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0018 0.0036 0.0036
Echinococcus granulosus survival motor neuron protein 1 0.0519 0.2868 0.4666
Loa Loa (eye worm) hypothetical protein 0.0063 0.029 0.0472
Echinococcus granulosus furin 0.1099 0.6146 1
Onchocerca volvulus Huntingtin homolog 0.0269 0.1453 0.4965
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Leishmania major subtilisin-like serine peptidase 0.0055 0.0245 0.6529
Echinococcus granulosus Furin 1 0.0353 0.1928 0.3137
Schistosoma mansoni hypothetical protein 0.0459 0.2527 0.4111
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0055 0.0245 0.0398
Loa Loa (eye worm) intermediate filament protein 0.0059 0.0267 0.0435
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0055 0.0245 0.0258
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0047 0.0196 0.4996
Onchocerca volvulus 0.0059 0.0267 0.0895
Echinococcus granulosus GPCR family 2 0.005 0.0213 0.0347
Loa Loa (eye worm) patched family protein 0.0013 0.0006 0.001
Trypanosoma brucei heat shock protein, putative 0.0036 0.0138 0.3692
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0045 0.5
Brugia malayi Niemann-Pick C1 protein precursor 0.0216 0.1155 0.1879
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0203 0.108 0.3684
Plasmodium falciparum heat shock protein 90 0.0036 0.0138 0.477
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0029 0.0096 0.0831
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0029 0.0096 0.0157
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0033 0.0119 0.0194
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0033 0.0119 0.0194
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0033 0.0119 0.0194
Loa Loa (eye worm) hypothetical protein 0.0027 0.0088 0.0143
Loa Loa (eye worm) hypothetical protein 0.0033 0.0119 0.0194
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Echinococcus multilocularis enteropeptidase 0.0049 0.0212 0.0212
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0033 0.0119 0.0387
Trypanosoma brucei heat shock protein, putative 0.0036 0.0138 0.3692
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0033 0.0119 0.0194
Echinococcus multilocularis thyroid hormone receptor alpha 0.0033 0.0119 0.0119
Trypanosoma cruzi heat shock protein 85, putative 0.0036 0.0138 0.3396
Plasmodium falciparum importin beta, putative 0.0063 0.029 1
Brugia malayi N-terminal motif family protein 0.0203 0.108 0.1757
Brugia malayi tailless protein 0.0016 0.002 0.0033
Loa Loa (eye worm) MH2 domain-containing protein 0.0262 0.1415 0.2301
Brugia malayi Patched protein homolog 1 0.0013 0.0006 0.001
Brugia malayi proprotein convertase 2 0.086 0.4797 0.7804
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.021 0.021
Trypanosoma brucei Heat shock protein 83, putative 0.0036 0.0138 0.3692
Echinococcus multilocularis protein patched 0.0093 0.0457 0.0457
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0033 0.0119 0.0194
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0015 0.0017 0.0027
Trypanosoma cruzi heat shock protein 90, putative 0.0022 0.0054 0.1039
Schistosoma mansoni RAR-like nuclear receptor 0.0033 0.0119 0.0194
Brugia malayi Fibulin-1 precursor 0.0014 0.0009 0.0014
Brugia malayi CXXC zinc finger family protein 0.0032 0.0114 0.0186
Toxoplasma gondii subtilisin SUB8 0.0055 0.0245 0.8435
Entamoeba histolytica hypothetical protein 0.0079 0.0379 0.3282
Brugia malayi nuclear receptor NHR-88 0.0016 0.002 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0073
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0073
Entamoeba histolytica Ran family GTPase 0.0047 0.0196 0.1696
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0016 0.002 0.0033
Brugia malayi endoprotease bli-4 precursor 0.1099 0.6146 1
Echinococcus granulosus endoplasmin 0.0029 0.0096 0.0157
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0213 0.0347
Mycobacterium ulcerans heat shock protein 90 0.0029 0.0096 0.0065
Loa Loa (eye worm) hypothetical protein 0.0058 0.0261 0.0425
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0094 0.0094
Echinococcus granulosus Niemann Pick C1 protein 0.0216 0.1155 0.1879
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Trypanosoma brucei heat shock protein, putative 0.0036 0.0138 0.3692
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0319 0.0519
Trypanosoma cruzi polo-like protein kinase, putative 0.0078 0.0375 1
Brugia malayi Smad1 0.0018 0.0033 0.0054
Echinococcus granulosus thyroid hormone receptor alpha 0.0016 0.002 0.0033
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0016 0.002 0.002
Brugia malayi Myosin head containing protein 0.0013 0.0006 0.001
Toxoplasma gondii subtilisin SUB12 0.0055 0.0245 0.8435
Schistosoma mansoni retinoic acid receptor RXR 0.0033 0.0119 0.0194
Trichomonas vaginalis hypothetical protein 0.025 0.1347 0.4109
Brugia malayi Ets-domain containing protein 0.0081 0.0388 0.0632
Brugia malayi Nuclear hormone receptor E75 0.0016 0.002 0.0033
Brugia malayi hypothetical protein 0.0013 0.0006 0.001
Onchocerca volvulus Huntingtin homolog 0.0269 0.1453 0.4965
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0016 0.002 0.0033
Schistosoma mansoni ap endonuclease 0.0027 0.0082 0.0134
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0033 0.0119 0.0194
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0016 0.002 0.0033
Loa Loa (eye worm) hypothetical protein 0.0114 0.0575 0.0935
Schistosoma mansoni nuclear hormone receptor 0.0016 0.002 0.0033
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.0128 0.0128
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0114 0.0186
Echinococcus granulosus ecdysone induced protein 78C 0.0033 0.0119 0.0194
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0051 0.0223 0.0679
Brugia malayi MH2 domain containing protein 0.0018 0.0033 0.0054
Brugia malayi latrophilin 2 splice variant baaae 0.0107 0.054 0.0878
Echinococcus multilocularis epidermal growth factor receptor 0.0182 0.0963 0.0963
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0016 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0157 0.0821 0.1336
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0073
Brugia malayi hypothetical protein 0.0016 0.002 0.0033
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Plasmodium vivax ataxin-2 like protein, putative 0.0041 0.0164 0.5638
Trichomonas vaginalis CAMK family protein kinase 0.0078 0.0375 0.1144
Echinococcus granulosus Niemann Pick C1 protein 0.0309 0.1679 0.2732
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0298 0.1616 0.4929
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0016 0.002 0.0033
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0591 0.3278 0.3278
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Plasmodium falciparum ataxin-2 like protein, putative 0.0041 0.0164 0.5638
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0033 0.0119 0.0194
Schistosoma mansoni transcription factor LCR-F1 0.0079 0.0379 0.0617
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0035 0.0128 0.3425
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0078 0.0375 0.061
Schistosoma mansoni nuclear hormone receptor 0.0016 0.002 0.0033
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0073
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0277 0.9557
Schistosoma mansoni site-1 peptidase (S08 family) 0.0055 0.0245 0.0398
Echinococcus multilocularis glycoprotein Antigen 5 0.0049 0.0212 0.0212
Echinococcus multilocularis expressed conserved protein 0.0203 0.1081 0.1081
Onchocerca volvulus Arrow homolog 0.0014 0.0009 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0245 0.0747
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0033 0.0119 0.0119
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0106 0.0531 0.0864
Trichomonas vaginalis conserved hypothetical protein 0.025 0.1347 0.4109
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0014 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0083 0.0055
Schistosoma mansoni heat shock protein 0.0036 0.0138 0.0225
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0033 0.0119 0.0194
Loa Loa (eye worm) hypothetical protein 0.0033 0.0119 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0245 0.0747
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0119 0.0119
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0015 0.0017 0.0017
Trypanosoma cruzi heat shock protein 85, putative 0.0029 0.0096 0.2225
Brugia malayi Patched family protein 0.0013 0.0006 0.001
Entamoeba histolytica hypothetical protein 0.0079 0.0379 0.3282
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0033 0.0119 0.0194
Trypanosoma brucei heat shock protein, putative 0.0036 0.0138 0.3692
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0591 0.3278 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0119 0.0194
Loa Loa (eye worm) hypothetical protein 0.0033 0.0119 0.0194
Brugia malayi hypothetical protein 0.0013 0.0006 0.001
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0152 0.0465
Trypanosoma brucei PAB1-binding protein , putative 0.0041 0.0164 0.4364
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0083 0.0048
Loa Loa (eye worm) hypothetical protein 0.005 0.0213 0.0347
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0031 0.005
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0078 0.0375 1
Giardia lamblia Kinase, PLK 0.0078 0.0375 0.191
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Plasmodium falciparum cysteine repeat modular protein 1 0.0018 0.0033 0.1141
Loa Loa (eye worm) DR-78 0.0016 0.002 0.0033
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0031 0.005
Toxoplasma gondii patched family protein 0.0013 0.0006 0.0221
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Echinococcus multilocularis integrin alpha ps 0.0068 0.0315 0.0315
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0033 0.0119 0.0194
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.0128 0.3117
Schistosoma mansoni tyrosine kinase 0.0182 0.0963 0.1566
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0078 0.0375 0.061
Treponema pallidum heat shock protein 90 0.0029 0.0096 1
Onchocerca volvulus 0.0027 0.0083 0.0263
Trypanosoma brucei importin beta-1 subunit, putative 0.0063 0.029 0.774
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0245 0.0747
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0107 0.054 0.0878
Schistosoma mansoni thyroid hormone receptor 0.0033 0.0119 0.0194
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0033
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0055 0.0245 0.0747
Loa Loa (eye worm) hypothetical protein 0.0176 0.093 0.1513
Brugia malayi photoreceptor-specific nuclear receptor 0.0033 0.0119 0.0194
Loa Loa (eye worm) hypothetical protein 0.0055 0.0245 0.0398
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0114 0.0579 0.0942
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0059 0.0267 0.0435
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0083 0.0048
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0027 0.0082 0.1826
Toxoplasma gondii Hsp90 domain-containing protein 0.0015 0.0017 0.0578
Brugia malayi MH2 domain containing protein 0.0018 0.0033 0.0054
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Leishmania major heat shock protein 83-1 0.0036 0.0138 0.3692
Onchocerca volvulus 0.0141 0.0729 0.2481
Onchocerca volvulus Serine\/threonine kinase homolog 0.0078 0.0375 0.1265
Echinococcus granulosus integrin alpha 3 0.0116 0.0587 0.0956
Echinococcus multilocularis endoplasmin 0.0029 0.0096 0.0096
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0353 0.1928 0.5883
Schistosoma mansoni lamin 0.0059 0.0267 0.0435
Schistosoma mansoni hypothetical protein 0.0089 0.0438 0.0712
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0083 0.0135
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0033 0.0119 0.0194
Plasmodium vivax subtilisin-like protease 2, putative 0.0055 0.0245 0.8435
Loa Loa (eye worm) nuclear hormone receptor 0.0112 0.0566 0.0921
Schistosoma mansoni integrin alpha-ps 0.0035 0.0132 0.0214
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0031 0.005
Toxoplasma gondii subtilisin SUB9 0.0055 0.0245 0.8435
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0353 0.1928 0.5883
Toxoplasma gondii patched family protein 0.0013 0.0006 0.0221
Brugia malayi Hsp90 protein 0.0015 0.0017 0.0027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.021 0.0342
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0219 0.1174 0.1909
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0094 0.0153
Echinococcus granulosus smad 0.0018 0.0033 0.0054
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.001
Echinococcus multilocularis geminin 0.0165 0.0866 0.0866
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0055 0.0245 1
Schistosoma mansoni hypothetical protein 0.0018 0.0036 0.0059
Brugia malayi serine/threonine-protein kinase plk-2 0.0078 0.0375 0.061
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0033 0.0054
Brugia malayi Latrophilin receptor protein 2 0.005 0.0213 0.0347
Loa Loa (eye worm) hypothetical protein 0.0033 0.0119 0.0194
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0047 0.0196 0.6744
Brugia malayi hypothetical protein 0.0026 0.0082 0.0133
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0119 0.0194

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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