Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.1013 | 0.1504 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0073 | 0.4097 | 1 |
Leishmania major | cathepsin L-like protease | 0.0073 | 0.4097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0073 | 0.4097 | 1 |
Leishmania major | cathepsin L-like protease | 0.0073 | 0.4097 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.3744 | 0.5694 |
Onchocerca volvulus | 0.0019 | 0.0467 | 1 | |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0162 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0019 | 0.0467 | 0.1249 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.2511 | 0.3818 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0068 | 0.3744 | 0.3718 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.6575 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0051 | 0.2601 | 0.2571 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2601 | 0.3955 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0067 | 0.367 | 0.8824 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.2511 | 0.6706 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0051 | 0.2601 | 0.2571 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0019 | 0.0467 | 0.1249 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0051 | 0.2601 | 0.6946 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0073 | 0.4097 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0051 | 0.2601 | 0.6946 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.3744 | 0.5694 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0073 | 0.4097 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0467 | 0.0429 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.2511 | 0.248 |
Echinococcus multilocularis | GPCR, family 2 | 0.0051 | 0.2601 | 0.6946 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.1013 | 0.1504 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1013 | 0.0977 |
Onchocerca volvulus | Cathepsin L homolog | 0.0019 | 0.0467 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.1013 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0068 | 0.3744 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2601 | 0.3955 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0019 | 0.0467 | 0.1249 |
Loa Loa (eye worm) | fibroinase | 0.0019 | 0.0467 | 0.0429 |
Entamoeba histolytica | cysteine protease, putative | 0.0019 | 0.0467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0019 | 0.0467 | 1 |
Leishmania major | cathepsin L-like protease | 0.0073 | 0.4097 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.2511 | 0.6706 |
Loa Loa (eye worm) | ctsf protein | 0.0019 | 0.0467 | 0.0429 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0019 | 0.0467 | 0.0429 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0467 | 0.0429 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0019 | 0.0467 | 0.0429 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0073 | 0.4097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0467 | 0.0429 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.011 | 0.6575 | 0.6561 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0073 | 0.4097 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.6575 | 0.6561 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0073 | 0.4097 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.1013 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.3744 | 0.5694 |
Echinococcus granulosus | cathepsin l1 | 0.0013 | 0.004 | 0.0108 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0073 | 0.4097 | 1 |
Onchocerca volvulus | 0.0019 | 0.0467 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0467 | 0.0429 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0073 | 0.4097 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0467 | 0.0429 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.1013 | 0.1504 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0058 | 0.3044 | 0.7098 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0073 | 0.4097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0019 | 0.0467 | 0.0429 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0362 | 0.0323 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0019 | 0.0467 | 0.0429 |
Echinococcus multilocularis | tar DNA binding protein | 0.0068 | 0.3744 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0019 | 0.0467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2601 | 0.2571 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0051 | 0.2601 | 0.6946 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0019 | 0.0467 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.1013 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0019 | 0.0467 | 0.1249 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.0467 | 0.0711 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0162 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0019 | 0.0467 | 0.1249 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.2511 | 0.248 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0051 | 0.2601 | 0.6946 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2601 | 0.3955 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.3744 | 0.5694 |
Loa Loa (eye worm) | RNA binding protein | 0.0068 | 0.3744 | 0.3718 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0073 | 0.4097 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.2511 | 0.6706 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2601 | 0.3955 |
Loa Loa (eye worm) | TAR-binding protein | 0.0068 | 0.3744 | 0.3718 |
Brugia malayi | TAR-binding protein | 0.0068 | 0.3744 | 0.3718 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0073 | 0.4097 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0019 | 0.0467 | 0.1249 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0013 | 0.004 | 0.0062 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.2511 | 0.3818 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.0467 | 0.0711 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0467 | 0.0429 |
Onchocerca volvulus | 0.0019 | 0.0467 | 1 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.3744 | 0.5694 |
Onchocerca volvulus | 0.0019 | 0.0467 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0051 | 0.2601 | 0.2571 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.2511 | 0.3818 |
Brugia malayi | RNA binding protein | 0.0068 | 0.3744 | 0.3718 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0073 | 0.4097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.2511 | 0.6706 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0019 | 0.0467 | 0.1249 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0019 | 0.0467 | 0.1249 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0019 | 0.0467 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0019 | 0.0467 | 0.1249 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0467 | 0.0429 |
Onchocerca volvulus | 0.0019 | 0.0467 | 1 | |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.1013 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0073 | 0.4097 | 1 |
Brugia malayi | hypothetical protein | 0.0027 | 0.1013 | 0.0977 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0073 | 0.4097 | 1 |
Onchocerca volvulus | 0.0019 | 0.0467 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Onchocerca volvulus | 0.0019 | 0.0467 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 1 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0051 | 0.2601 | 0.6946 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0467 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0068 | 0.3744 | 0.3718 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.