Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0043 | 0.1115 | 1 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0013 | 0.0115 | 0.5 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0055 | 0.1553 | 0.1553 |
Brugia malayi | mbt repeat family protein | 0.0049 | 0.1323 | 0.2124 |
Schistosoma mansoni | alpha glucosidase | 0.0043 | 0.1115 | 0.1115 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0192 | 0.6226 | 0.6226 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0016 | 0.02 | 0.0974 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0626 | 0.5177 |
Mycobacterium tuberculosis | Probable reductase | 0.0088 | 0.267 | 0.8837 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0504 | 0.0809 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0043 | 0.1115 | 0.1115 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0314 | 0.0314 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0013 | 0.0115 | 0.0184 |
Schistosoma mansoni | alpha-glucosidase | 0.0165 | 0.5311 | 0.5311 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.037 | 0.2653 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0314 | 0.2097 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.1434 | 0.1434 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0115 | 0.0134 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0013 | 0.0115 | 0.0134 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0115 | 0.0134 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0504 | 0.2834 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.1434 | 0.1434 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0314 | 0.1197 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0088 | 0.267 | 0.8837 |
Brugia malayi | RNA, U transporter 1 | 0.008 | 0.2412 | 0.3874 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0013 | 0.0115 | 0.0645 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0098 | 0.3006 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0314 | 0.0314 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0043 | 0.1115 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0039 | 0.0978 | 0.0978 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0016 | 0.02 | 0.0974 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0013 | 0.0115 | 0.0134 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.037 | 0.0594 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.1434 | 0.1434 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0049 | 0.1323 | 0.1323 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.037 | 0.2653 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.037 | 0.037 |
Brugia malayi | glutathione reductase | 0.0039 | 0.0978 | 0.157 |
Onchocerca volvulus | 0.0111 | 0.3456 | 1 | |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0016 | 0.02 | 0.0321 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0013 | 0.0115 | 0.0115 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0049 | 0.1323 | 0.1323 |
Echinococcus multilocularis | snurportin 1 | 0.0302 | 1 | 1 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0013 | 0.0115 | 0.0115 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0314 | 0.0314 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0052 | 0.1434 | 0.2304 |
Trypanosoma brucei | trypanothione reductase | 0.0039 | 0.0978 | 0.8651 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0115 | 0.0134 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.037 | 0.2653 |
Onchocerca volvulus | 0.0049 | 0.1323 | 0.3448 | |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0088 | 0.267 | 0.8837 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0192 | 0.6226 | 0.6226 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.1115 | 1 |
Plasmodium vivax | glutathione reductase, putative | 0.0039 | 0.0978 | 1 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.037 | 0.2653 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0049 | 0.1323 | 0.1323 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0314 | 1 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0013 | 0.0115 | 0.0081 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.1434 | 0.1434 |
Trypanosoma brucei | glucosidase, putative | 0.0043 | 0.1115 | 1 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.037 | 0.2081 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0024 | 0.0488 | 0.3821 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1553 | 0.1553 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.1777 | 0.1777 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0013 | 0.0115 | 0.0134 |
Leishmania major | trypanothione reductase | 0.0039 | 0.0978 | 0.5231 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0504 | 0.3974 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0314 | 0.2097 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.1115 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0314 | 0.0314 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0049 | 0.1323 | 0.3448 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0115 | 0.0134 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0626 | 0.352 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0016 | 0.02 | 0.0974 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0504 | 0.3974 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.1115 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0039 | 0.0978 | 0.157 |
Plasmodium falciparum | thioredoxin reductase | 0.0013 | 0.0115 | 0.1172 |
Schistosoma mansoni | ran | 0.0021 | 0.037 | 0.037 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.037 | 0.2653 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0016 | 0.02 | 0.0974 |
Schistosoma mansoni | ran | 0.0021 | 0.037 | 0.037 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0016 | 0.02 | 0.0974 |
Echinococcus multilocularis | bloom syndrome protein | 0.0024 | 0.0488 | 0.0488 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0314 | 0.1764 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0314 | 0.3207 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.1777 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0039 | 0.0978 | 0.8651 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0192 | 0.6226 | 0.6226 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 0.1434 | 0.1434 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0013 | 0.0115 | 0.0134 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0039 | 0.0978 | 0.2985 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0013 | 0.0115 | 0.0134 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0192 | 0.6226 | 0.6226 |
Schistosoma mansoni | hypothetical protein | 0.03 | 0.9916 | 0.9916 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.1434 | 0.1434 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.1115 | 1 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.0037 | 0.0037 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0055 | 0.1553 | 0.1553 |
Loa Loa (eye worm) | glutathione reductase | 0.0039 | 0.0978 | 0.0978 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0043 | 0.1115 | 1 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0043 | 0.1115 | 0.6046 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0055 | 0.1553 | 0.1553 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0049 | 0.1323 | 0.1323 |
Plasmodium falciparum | glutathione reductase | 0.0039 | 0.0978 | 1 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0626 | 0.0626 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0039 | 0.0978 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0049 | 0.1323 | 0.1323 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.1115 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0314 | 0.2097 |
Schistosoma mansoni | hypothetical protein | 0.0302 | 1 | 1 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0442 | 0.3369 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0314 | 0.0504 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.02 | 0.02 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0043 | 0.1115 | 0.6271 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0314 | 0.8478 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0055 | 0.1553 | 0.1553 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0016 | 0.02 | 0.0974 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0098 | 0.3006 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0314 | 0.2305 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0016 | 0.02 | 0.0974 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0314 | 0.1268 |
Trypanosoma brucei | glycosyl hydrolase-like protein | 0.0016 | 0.02 | 0.0974 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0049 | 0.1323 | 0.1323 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0043 | 0.1115 | 0.179 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0043 | 0.1115 | 1 |
Brugia malayi | mbt repeat family protein | 0.0049 | 0.1323 | 0.2124 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0024 | 0.0488 | 0.0784 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0442 | 0.3369 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.037 | 0.2957 |
Loa Loa (eye worm) | RecQ helicase | 0.0024 | 0.0488 | 0.0488 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0504 | 0.4508 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.1777 | 1 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0626 | 0.5177 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0013 | 0.0115 | 0.1172 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0013 | 0.0115 | 0.0134 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0196 | 0.6354 | 0.6354 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.1777 | 0.575 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0098 | 0.3006 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.1777 | 0.1777 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0013 | 0.0115 | 0.0134 |
Schistosoma mansoni | alpha-glucosidase | 0.0165 | 0.5311 | 0.5311 |
Loa Loa (eye worm) | MBCTL1 | 0.0055 | 0.1553 | 0.1553 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0314 | 1 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0024 | 0.0488 | 0.3821 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0013 | 0.0115 | 0.0134 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0043 | 0.1115 | 0.1115 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0016 | 0.02 | 0.0974 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.037 | 0.1604 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0314 | 0.2097 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0212 | 0.1195 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.1777 | 0.1777 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0039 | 0.0995 | 0.0995 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0039 | 0.0995 | 0.0995 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0626 | 0.0626 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0314 | 0.2097 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0016 | 0.02 | 0.0974 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.037 | 0.037 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.3842 | 0.3842 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.1434 | 0.1434 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0013 | 0.0115 | 0.0134 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0013 | 0.0115 | 0.0081 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0049 | 0.1323 | 0.1323 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.1115 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0037 | 0.0037 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0043 | 0.1115 | 0.1115 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0196 | 0.6354 | 0.6354 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0387 | 0.396 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0013 | 0.0115 | 0.1172 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0013 | 0.0115 | 0.3097 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0088 | 0.267 | 0.8837 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0088 | 0.267 | 0.8837 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.0037 | 0.0037 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0314 | 0.0688 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.1777 | 0.1777 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0192 | 0.6226 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0314 | 0.2097 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0626 | 0.0626 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0043 | 0.1115 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0115 | 0.0081 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0013 | 0.0115 | 0.0115 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0504 | 0.5152 |
Echinococcus granulosus | bloom syndrome protein | 0.0024 | 0.0488 | 0.0488 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0302 | 1 | 1 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0055 | 0.1553 | 0.2495 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0098 | 0.3006 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0504 | 0.0504 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0442 | 0.3369 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.1434 | 0.1434 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0626 | 0.5921 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0016 | 0.0219 | 0.121 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0626 | 0.0626 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.037 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0115 | 0.0134 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0442 | 0.2037 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0314 | 0.0314 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.1777 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0016 | 0.02 | 0.0974 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0055 | 0.1553 | 0.1553 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0504 | 0.5152 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.00000000015631 | 0.0000000008795 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0626 | 0.6399 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0088 | 0.267 | 0.8837 |
Plasmodium falciparum | glutathione reductase | 0.0013 | 0.0115 | 0.1172 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0442 | 0.3369 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.037 | 0.037 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0442 | 0.3369 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1323 | 0.1323 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.1115 | 1 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0013 | 0.0115 | 0.0645 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0049 | 0.1323 | 0.1323 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0626 | 0.1005 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.0313 | 0.0313 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0504 | 0.2403 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.037 | 0.3783 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0115 | 0.0081 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0504 | 0.3974 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.1777 | 1 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0204 | 0.0327 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0043 | 0.1115 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0013 | 0.0115 | 0.0134 |
Plasmodium falciparum | thioredoxin reductase | 0.0039 | 0.0978 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0016 | 0.02 | 0.0974 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.1777 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.0039 | 0.0978 | 0.5502 |
Leishmania major | glycosyl hydrolase-like protein | 0.0016 | 0.02 | 0.0589 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.