Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.1168 | 0.1467 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.6567 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0157 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0339 | 0.0157 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.1168 | 0.1168 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.1168 | 0.1467 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.1168 | 0.1168 |
Schistosoma mansoni | zinc finger protein | 0.0005 | 0.024 | 0.024 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.1168 | 0.1168 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0157 |
Onchocerca volvulus | 0.0032 | 0.4403 | 1 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.024 | 0.024 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0005 | 0.024 | 0.024 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0956 | 0.1131 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.1131 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0339 | 0.0157 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Plasmodium falciparum | zinc finger protein, putative | 0.0004 | 0 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.6567 | 0.6567 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.024 | 0.024 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.1168 | 0.1467 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.4688 | 0.703 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.1168 | 0.1467 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0006 | 0.0339 | 0.0157 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.1168 | 0.1168 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.1168 | 0.1467 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.1131 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0005 | 0.024 | 0.024 |
Brugia malayi | nuclear receptor RXR | 0.0006 | 0.0339 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.1168 | 0.1168 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.1168 | 0.1467 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.1168 | 0.1168 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.1168 | 0.1467 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.4688 | 0.703 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0006 | 0.0339 | 0.0339 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.6567 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.1168 | 0.1168 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.6567 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.1168 | 0.1168 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0157 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.1168 | 0.1467 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.1168 | 0.1467 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.6567 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.1168 | 0.1467 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0542 | 1 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0936 | 0.11 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0651 | 0.065 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.1168 | 0.1168 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0005 | 0.024 | 0.024 |
Entamoeba histolytica | hypothetical protein | 0.0004 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.1168 | 0.1467 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.1168 | 0.1467 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.4688 | 0.4688 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0157 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.1467 |
Onchocerca volvulus | 0.0011 | 0.1168 | 0.2229 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.6567 | 0.6567 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.4403 | 0.658 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.1168 | 0.1168 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0157 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.1168 | 0.1467 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.8869 | 0.5 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0651 | 0.065 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0006 | 0.0339 | 0.0157 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.6567 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0006 | 0.0339 | 0.0157 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0011 | 0.1168 | 0.2229 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0651 | 0.065 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0339 | 0.0157 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0005 | 0.0127 | 0.0127 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.024 | 0.024 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.1168 | 0.1467 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.1168 | 0.1467 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0651 | 0.0651 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.6567 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0006 | 0.0339 | 0.0339 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.4688 | 0.4688 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.1168 | 0.1168 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0339 | 0.0157 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0011 | 0.1168 | 0.2229 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.1168 | 0.1467 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0651 | 0.065 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.1168 | 0.1467 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.1168 | 0.1467 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.4403 | 0.658 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0011 | 0.1168 | 0.2229 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.6567 | 0.6567 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.024 | 0.024 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.1168 | 0.1467 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.1168 | 0.1168 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.4403 | 0.4403 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.1168 | 0.1168 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.1168 | 0.1467 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.