Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0459 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0636 | 0.0665 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.0636 | 0.2528 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0011 | 0.0007 | 0.0007 |
Brugia malayi | PHD-finger family protein | 0.0011 | 0.0015 | 0.0015 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0037 | 0.0039 |
Echinococcus granulosus | dna polymerase kappa | 0.0022 | 0.0636 | 0.0636 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0124 | 0.6488 | 0.8837 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0037 | 0.0039 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0419 | 0.0419 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0011 | 0.0007 | 0.0028 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0124 | 0.6488 | 0.8837 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0037 | 0.0037 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0037 | 0.0039 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0022 | 0.0636 | 0.0636 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0037 | 0.0037 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0037 | 0.0037 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0019 | 0.0459 | 0.1816 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0419 | 0.0419 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0037 | 0.0039 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0459 | 0.1816 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0019 | 0.0459 | 0.1816 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0011 | 0.0007 | 0.0007 |
Plasmodium vivax | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0014 | 0.0197 | 0.0762 |
Plasmodium vivax | glutathione reductase, putative | 0.0054 | 0.2495 | 1 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.0011 | 0.0015 | 0.0032 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0019 | 0.0459 | 0.1839 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0011 | 0.0007 | 0.0007 |
Entamoeba histolytica | phosphoinositide kinase, putative | 0.0014 | 0.0197 | 0.0307 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0054 | 0.2495 | 0.2985 |
Brugia malayi | AF-10 protein | 0.0011 | 0.0015 | 0.0015 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0037 | 0.0039 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase type II beta, putative | 0.0014 | 0.0197 | 0.0762 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.1625 | 0.1625 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0015 | 0.0015 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0419 | 0.0419 |
Echinococcus granulosus | phosphatidylinositol 5 phosphate 4 kinase type 2 | 0.0178 | 0.9567 | 0.9567 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0019 | 0.0459 | 0.1816 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0037 | 0.0037 |
Brugia malayi | Pip kinase protein 1 | 0.0014 | 0.0197 | 0.0206 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0057 | 0.2665 | 0.2785 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0019 | 0.0459 | 0.1816 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0011 | 0.0007 | 0.0007 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0037 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0007 |
Schistosoma mansoni | jumonji domain containing protein | 0.0011 | 0.0007 | 0.0007 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0459 | 0.1816 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0037 | 0.0037 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0037 | 0.0037 |
Leishmania major | trypanothione reductase | 0.0054 | 0.2495 | 1 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0019 | 0.0459 | 0.394 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.0011 | 0.0015 | 0.0032 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0019 | 0.0459 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0037 | 0.0039 |
Echinococcus multilocularis | bloom syndrome protein | 0.0026 | 0.0884 | 0.0884 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0011 | 0.0007 | 0.0007 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0419 | 0.0419 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0026 | 0.0884 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0037 | 0.0039 |
Loa Loa (eye worm) | glutathione reductase | 0.0054 | 0.2495 | 0.2608 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0037 | 0.0039 |
Echinococcus multilocularis | dna polymerase eta | 0.0022 | 0.0636 | 0.0636 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0022 | 0.0636 | 0.0636 |
Brugia malayi | jmjC domain containing protein | 0.0011 | 0.0007 | 0.0007 |
Trypanosoma brucei | unspecified product | 0.0022 | 0.0636 | 0.2528 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0034 | 0.1324 | 0.1324 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0459 | 0.1816 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0054 | 0.2495 | 0.2495 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0014 | 0.0197 | 0.0197 |
Schistosoma mansoni | hypothetical protein | 0.0185 | 1 | 1 |
Trypanosoma cruzi | phosphatidylinositol (3,5) kinase, putative | 0.0014 | 0.0197 | 0.0762 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.0246 | 0.096 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0037 | 0.0037 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0419 | 0.0419 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0019 | 0.0459 | 0.048 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0111 | 0.5751 | 0.5751 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0019 | 0.0459 | 0.1839 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.2665 | 0.2785 |
Brugia malayi | Bromodomain containing protein | 0.0034 | 0.1324 | 0.1384 |
Toxoplasma gondii | phosphatidylinositol-4-phosphate 5-Kinase | 0.0014 | 0.0197 | 0.0788 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0019 | 0.0459 | 0.1816 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0011 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0022 | 0.0636 | 0.0665 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0023 | 0.0701 | 0.2808 |
Trichomonas vaginalis | phosphatidylinositol-4-phosphate 5-kinase type II, putative | 0.0014 | 0.0197 | 0.0198 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0037 | 0.0039 |
Schistosoma mansoni | protein phosphatase 2C | 0.0011 | 0.0007 | 0.0007 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0124 | 0.6488 | 0.8837 |
Plasmodium falciparum | thioredoxin reductase | 0.0054 | 0.2495 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0037 | 0.0039 |
Echinococcus multilocularis | phd:f box containing protein | 0.0011 | 0.0007 | 0.0007 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0026 | 0.0884 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0022 | 0.0636 | 0.0665 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0011 | 0.0007 | 0.0007 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0007 | 0.0007 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0459 | 0.1816 |
Trypanosoma brucei | unspecified product | 0.0015 | 0.0246 | 0.096 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0178 | 0.9567 | 0.9567 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | RecQ helicase | 0.0026 | 0.0884 | 0.0924 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0124 | 0.6488 | 0.8837 |
Trypanosoma brucei | unspecified product | 0.0015 | 0.0246 | 0.096 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0037 | 0.0037 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0019 | 0.0459 | 0.0459 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0037 | 0.0039 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0034 | 0.1324 | 0.1384 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0022 | 0.0636 | 0.026 |
Trypanosoma brucei | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0014 | 0.0197 | 0.0762 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0014 | 0.0172 | 0.018 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | pip kinase 2 | 0.0178 | 0.9567 | 1 |
Brugia malayi | Pip kinase protein 2 | 0.0178 | 0.9567 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0037 | 0.0039 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0138 | 0.7281 | 1 |
Loa Loa (eye worm) | FYVE zinc finger family protein | 0.0014 | 0.0197 | 0.0206 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0014 | 0.0197 | 0.0762 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0037 | 0.0037 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0419 | 0.0419 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0019 | 0.0459 | 0.5 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0054 | 0.2495 | 1 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0026 | 0.0884 | 0.0924 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0037 | 0.0039 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0037 | 0.0039 |
Echinococcus granulosus | Phosphatidylinositol 4 phosphate 5 kinase type 1 | 0.0014 | 0.0197 | 0.0197 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0011 | 0.0007 | 0.0007 |
Onchocerca volvulus | Alhambra homolog | 0.0034 | 0.1324 | 0.1351 |
Schistosoma mansoni | DNA polymerase eta | 0.0022 | 0.0636 | 0.0636 |
Echinococcus granulosus | jumonji domain containing protein | 0.0047 | 0.2086 | 0.2086 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0011 | 0.0007 | 0.0007 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0022 | 0.0636 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0057 | 0.2665 | 0.2785 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0037 | 0.0037 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0054 | 0.2495 | 1 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0011 | 0.0007 | 0.0028 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0037 | 0.0037 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0037 | 0.0037 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0014 | 0.0197 | 0.0762 |
Brugia malayi | PHD-finger family protein | 0.0034 | 0.1324 | 0.1384 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0037 | 0.0039 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0138 | 0.7281 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0037 | 0.0039 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0138 | 0.7281 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0037 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.6953 | 0.7268 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.0636 | 0.2528 |
Echinococcus granulosus | peregrin | 0.0034 | 0.1324 | 0.1324 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0.0636 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0011 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.2714 | 0.2837 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0.0636 | 1 |
Echinococcus multilocularis | geminin | 0.0185 | 1 | 1 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0178 | 0.9567 | 0.9567 |
Toxoplasma gondii | thioredoxin reductase | 0.0054 | 0.2495 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0041 | 0.1734 | 0.1734 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0022 | 0.0636 | 0.0665 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.9567 | 1 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0014 | 0.0172 | 0.018 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0037 | 0.0037 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type I | 0.0014 | 0.0197 | 0.0197 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0459 | 0.1816 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0022 | 0.0636 | 0.026 |
Loa Loa (eye worm) | pip kinase 1 | 0.0014 | 0.0197 | 0.0206 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0022 | 0.0636 | 0.2528 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0011 | 0.0007 | 0.0007 |
Leishmania major | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0037 | 0.0037 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0419 | 0.0419 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0419 | 0.0437 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1324 | 0.1324 |
Plasmodium falciparum | phd finger protein, putative | 0.0034 | 0.1324 | 0.5308 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0019 | 0.0459 | 0.1816 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0054 | 0.2495 | 0.2495 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0015 | 0.0015 |
Brugia malayi | glutathione reductase | 0.0054 | 0.2495 | 0.2608 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0019 | 0.0459 | 0.1816 |
Schistosoma mansoni | hypothetical protein | 0.0185 | 1 | 1 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0019 | 0.0459 | 0.1816 |
Giardia lamblia | PHD finger protein 15 | 0.0034 | 0.1324 | 1 |
Trypanosoma brucei | phosphatidylinositol (3,5) kinase, putative | 0.0014 | 0.0197 | 0.0762 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0014 | 0.0197 | 0.0197 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0037 | 0.0037 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0037 | 0.0039 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0037 | 0.0037 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0057 | 0.2665 | 0.2785 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0041 | 0.1734 | 0.1734 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0011 | 0.0015 | 0.0015 |
Echinococcus multilocularis | dna polymerase kappa | 0.0022 | 0.0636 | 0.0636 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0037 | 0.0037 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0037 | 0.0037 |
Leishmania major | phosphatidylinositol-4-phosphate 5-kinase-like, putative | 0.0014 | 0.0197 | 0.0762 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0183 | 0.0707 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0018 | 0.0384 | 0.154 |
Leishmania major | phosphatidylinositol-4-phosphate-5-kinase-likep ro tein | 0.0014 | 0.0197 | 0.0762 |
Giardia lamblia | Phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0014 | 0.0197 | 0.1484 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0037 | 0.0039 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0419 | 0.0419 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Toxoplasma gondii | phosphatidylinositol-4-phosphate 5-Kinase | 0.0014 | 0.0197 | 0.0788 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0037 | 0.0039 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0019 | 0.0459 | 0.1816 |
Trypanosoma brucei | trypanothione reductase | 0.0054 | 0.2495 | 1 |
Trypanosoma brucei | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0014 | 0.0197 | 0.0762 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0041 | 0.1734 | 0.1734 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0419 | 0.0437 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0111 | 0.5751 | 0.5751 |
Echinococcus granulosus | phd:f box containing protein | 0.0011 | 0.0007 | 0.0007 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0011 | 0.0007 | 0.0007 |
Plasmodium falciparum | glutathione reductase | 0.0019 | 0.0459 | 0.1839 |
Brugia malayi | FYVE finger-containing phosphoinositide kinase, putative | 0.0014 | 0.0197 | 0.0206 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Brugia malayi | jmjC domain containing protein | 0.0111 | 0.5751 | 0.6011 |
Leishmania major | phosphatidylinositol-4-phosphate 5-kinase-like protein | 0.0014 | 0.0197 | 0.0762 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0037 | 0.0039 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0041 | 0.1734 | 0.1734 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1625 | 0.1699 |
Plasmodium vivax | hypothetical protein, conserved | 0.0034 | 0.1324 | 0.5295 |
Plasmodium falciparum | phosphatidylinositol-4-phosphate 5-kinase | 0.0014 | 0.0197 | 0.0788 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0019 | 0.0459 | 0.1839 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0022 | 0.0636 | 0.0636 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0019 | 0.0459 | 0.394 |
Trichomonas vaginalis | phosphatidylinositol-4-phosphate 5-kinase type II, putative | 0.0014 | 0.0197 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0037 | 0.0039 |
Brugia malayi | jmjC domain containing protein | 0.0011 | 0.0007 | 0.0007 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0138 | 0.7281 | 1 |
Entamoeba histolytica | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0014 | 0.0197 | 0.0307 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0037 | 0.0037 |
Plasmodium falciparum | thioredoxin reductase | 0.0019 | 0.0459 | 0.1839 |
Schistosoma mansoni | jumonji domain containing protein | 0.0088 | 0.4441 | 0.4441 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0037 | 0.0039 |
Plasmodium falciparum | conserved Plasmodium membrane protein, unknown function | 0.0011 | 0.0015 | 0.0059 |
Plasmodium vivax | hypothetical protein, conserved | 0.0014 | 0.0197 | 0.0762 |
Brugia malayi | Thioredoxin reductase | 0.0054 | 0.2495 | 0.2608 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0037 | 0.0039 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase-like, putative | 0.0014 | 0.0197 | 0.0762 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0011 | 0.0015 | 0.0059 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase, putative | 0.0014 | 0.0197 | 0.0762 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0037 | 0.0039 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0022 | 0.0636 | 0.0636 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0034 | 0.1324 | 0.5308 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.0636 | 0.2528 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0419 | 0.0437 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0011 | 0.0007 | 0.0007 |
Leishmania major | phosphatidylinositol (3,5) kinase, putative | 0.0014 | 0.0197 | 0.0762 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0037 | 0.0037 |
Echinococcus multilocularis | Phosphatidylinositol 4 phosphate 5 kinase type 1 | 0.0014 | 0.0197 | 0.0197 |
Trypanosoma cruzi | phosphatidylinositol-4-phosphate 5-kinase-like, putative | 0.0014 | 0.0197 | 0.0762 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0037 | 0.0037 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0419 | 0.0419 |
Schistosoma mansoni | phd/f-box containing protein | 0.0011 | 0.0007 | 0.0007 |
Trypanosoma brucei | phosphatidylinositol phosphate kinase alpha | 0.0014 | 0.0197 | 0.0762 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0183 | 0.0707 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0022 | 0.0636 | 0.6467 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0034 | 0.1324 | 0.1324 |
Treponema pallidum | NADH oxidase | 0.0019 | 0.0459 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0037 | 0.0039 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0459 | 0.1816 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0037 | 0.0039 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0124 | 0.6488 | 0.8837 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0037 | 0.0039 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0183 | 0.0707 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0011 | 0.0007 | 0.0028 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0022 | 0.0636 | 0.2528 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0022 | 0.0636 | 0.2528 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0037 | 0.0037 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0419 | 0.0419 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0019 | 0.0459 | 0.0459 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0037 | 0.0039 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0034 | 0.1324 | 0.1324 |
Loa Loa (eye worm) | FYVE finger-containing phosphoinositide kinase | 0.0014 | 0.0197 | 0.0206 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0037 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1324 | 0.1384 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0037 | 0.0039 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0037 | 0.0039 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0037 | 0.0039 |
Trypanosoma cruzi | phosphatidylinositol 4-phosphate 5-kinase alpha, putative | 0.0014 | 0.0197 | 0.0762 |
Giardia lamblia | DINP protein human, muc B family | 0.0022 | 0.0636 | 0.4801 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0021 | 0.0567 | 0.0567 |
Brugia malayi | jmjC domain containing protein | 0.0011 | 0.0007 | 0.0007 |
Brugia malayi | jmjC domain containing protein | 0.0011 | 0.0007 | 0.0007 |
Echinococcus granulosus | dna polymerase eta | 0.0022 | 0.0636 | 0.0636 |
Toxoplasma gondii | phosphatidylinositol-4-phosphate 5-kinase | 0.0014 | 0.0197 | 0.0788 |
Onchocerca volvulus | 0.0178 | 0.9567 | 1 | |
Echinococcus multilocularis | phosphatidylinositol 5 phosphate 4 kinase type 2 | 0.0178 | 0.9567 | 0.9567 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate-5-kinaseputativ e | 0.0014 | 0.0197 | 0.0197 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0019 | 0.0459 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.0636 | 0.2528 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0019 | 0.0459 | 0.0459 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0019 | 0.0459 | 0.3465 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0047 | 0.2086 | 0.2086 |
Giardia lamblia | Hypothetical protein | 0.0014 | 0.0197 | 0.1484 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0419 | 0.0437 |
Echinococcus multilocularis | phosphatidylinositol phosphate 5 kinase type III | 0.0014 | 0.0197 | 0.0197 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0037 | 0.0037 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.0246 | 0.096 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0034 | 0.1324 | 0.5308 |
Mycobacterium tuberculosis | Probable reductase | 0.0124 | 0.6488 | 0.8837 |
Echinococcus granulosus | bloom syndrome protein | 0.0026 | 0.0884 | 0.0884 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0015 | 0.0246 | 0.096 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.1625 | 0.1699 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.007 | 0.3396 | 0.355 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0018 | 0.0396 | 0.1565 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0459 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0037 | 0.0039 |
Leishmania major | DNA polymerase eta, putative | 0.0022 | 0.0636 | 0.2528 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0022 | 0.0636 | 0.6467 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0037 | 0.0037 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0019 | 0.0459 | 0.5 |
Echinococcus granulosus | phosphatidylinositol phosphate 5 kinase type III | 0.0014 | 0.0197 | 0.0197 |
Echinococcus multilocularis | peregrin | 0.0034 | 0.1324 | 0.1324 |
Plasmodium falciparum | glutathione reductase | 0.0054 | 0.2495 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0019 | 0.0459 | 0.1816 |
Toxoplasma gondii | WD domain, G-beta repeat-containing protein | 0.0011 | 0.0015 | 0.0059 |
Brugia malayi | jmjC domain containing protein | 0.0041 | 0.1734 | 0.1812 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0019 | 0.0459 | 0.1839 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0041 | 0.1734 | 0.1812 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0037 | 0.0039 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0011 | 0.0015 | 0.0015 |
Plasmodium vivax | hypothetical protein, conserved | 0.0011 | 0.0015 | 0.0032 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0054 | 0.2495 | 0.2608 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.