Detailed information for compound 1158730

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 299.368 | Formula: C17H21N3O2
  • H donors: 0 H acceptors: 2 LogP: 1.15 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O(CC1OCCc2c1nn(c2)Cc1ccccn1)CC1CC1
  • InChi: 1S/C17H21N3O2/c1-2-7-18-15(3-1)10-20-9-14-6-8-22-16(17(14)19-20)12-21-11-13-4-5-13/h1-3,7,9,13,16H,4-6,8,10-12H2
  • InChiKey: PJGMIPSBGZFWQW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0312 0.2979 0.2979
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0274 0.0331
Schistosoma mansoni furin-1 (S08 family) 0.0026 0.0071 0.0085
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0206 0.0206
Toxoplasma gondii subtilisin SUB8 0.0026 0.0071 0.0405
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0268 0.1542
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0206 0.0206
Trypanosoma cruzi phosphoglycerate kinase, putative 0.007 0.0518 0.2977
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0035 0.0161 0.0922
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0026 0.0071 0.0326
Echinococcus multilocularis jumonji domain containing 1A 0.0035 0.0161 0.0161
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0175 0.1004
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0026 0.0071 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0071 0.0243
Schistosoma mansoni jumonji domain containing protein 0.0035 0.0161 0.0194
Schistosoma mansoni hypothetical protein 0.0159 0.1423 0.1719
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.126 0.5816
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0494 0.0597
Loa Loa (eye worm) hypothetical protein 0.0036 0.0178 0.0215
Mycobacterium ulcerans hypothetical protein 0.0036 0.0178 0.0612
Schistosoma mansoni rotamase 0.0034 0.0152 0.0183
Entamoeba histolytica phosphoglycerate kinase, putative 0.019 0.174 0.6259
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0152 0.0183
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.1277 0.1277
Loa Loa (eye worm) glutathione reductase 0.0037 0.0183 0.0221
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.2779 0.9551
Schistosoma mansoni glutaminase 0.0305 0.291 0.3516
Loa Loa (eye worm) hypothetical protein 0.0115 0.0974 0.1177
Mycobacterium tuberculosis Probable oxidoreductase 0.0093 0.0757 0.3495
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.1019 0.1231
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0151 0.0518
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0175 0.1005
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0312 0.2979 0.2979
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0178 0.0215
Echinococcus granulosus lamin 0.0053 0.0344 0.0344
Plasmodium vivax hypothetical protein, conserved 0.0057 0.0394 0.2262
Onchocerca volvulus 0.0053 0.0344 0.1272
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0084 0.0662 0.3055
Echinococcus multilocularis lamin dm0 0.0053 0.0344 0.0344
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.019 0.174 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0113 0.0113
Plasmodium falciparum subtilisin-like protease 1 0.0026 0.0071 0.0405
Trypanosoma brucei subtilisin peptidase 0.0026 0.0071 0.0407
Schistosoma mansoni lamin 0.0053 0.0344 0.0415
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0035 0.0161 0.0923
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0057 0.0195
Brugia malayi PHD-finger family protein 0.0057 0.0394 0.0476
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0023 0.0044 0.0149
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0035 0.0161 0.0161
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Loa Loa (eye worm) beta-lactamase 0.0036 0.0178 0.0215
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Loa Loa (eye worm) hypothetical protein 0.0036 0.0178 0.0215
Schistosoma mansoni phosphoglycerate kinase 0.019 0.174 0.2102
Schistosoma mansoni glutamate receptor kainate 0.0024 0.0056 0.0068
Leishmania major cytochrome p450-like protein 0.002 0.001 0.0059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0274 0.0274
Schistosoma mansoni tar DNA-binding protein 0.0329 0.3155 0.3812
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0081 0.0278
Echinococcus granulosus neuroendocrine convertase 2 0.0026 0.0071 0.0071
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0026 0.0071 0.0407
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0084 0.0662 0.3055
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0 0.0002
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0024 0.0056 0.0056
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0178 0.0612
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0268 0.0268
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Mycobacterium tuberculosis Probable dehydrogenase 0.0084 0.0662 0.3055
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Loa Loa (eye worm) acetyltransferase 0.0144 0.1277 0.1543
Loa Loa (eye worm) TAR-binding protein 0.0329 0.3155 0.3812
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0113 0.0646
Toxoplasma gondii ABC1 family protein 0.0036 0.0178 0.1023
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0096 0.0115
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0329 0.3155 0.3812
Echinococcus granulosus Furin 1 0.0026 0.0071 0.0071
Trichomonas vaginalis set domain proteins, putative 0.0237 0.2216 0.7617
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0057 0.0195
Loa Loa (eye worm) proprotein convertase 2 0.0026 0.0071 0.0085
Leishmania major hypothetical protein, conserved 0.0035 0.0161 0.0923
Schistosoma mansoni lamin 0.0053 0.0344 0.0415
Plasmodium vivax glutathione reductase, putative 0.0037 0.0183 0.1051
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0103 0.0103
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.007 0.0518 0.2977
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0057 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0084 0.0287
Loa Loa (eye worm) hypothetical protein 0.0057 0.0394 0.0476
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0178 0.0215
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0144 0.0824
Loa Loa (eye worm) CYP4Cod1 0.002 0.001 0.0012
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0012 0.0014
Echinococcus granulosus PHD finger protein rhinoceros 0.0057 0.0394 0.0394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0151 0.0518
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0032 0.0135 0.0135
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0248 0.2334 0.2334
Loa Loa (eye worm) hypothetical protein 0.0025 0.0067 0.0081
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0026 0.0071 0.0243
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0178 0.1023
Brugia malayi Calcitonin receptor-like protein seb-1 0.0502 0.491 0.5933
Brugia malayi celfurPC protein 0.0026 0.0071 0.0085
Mycobacterium ulcerans phosphoglycerate kinase 0.019 0.174 0.5978
Echinococcus granulosus glutamate NMDA receptor subunit 0.0024 0.0056 0.0056
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.001 0.0035
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0103 0.0103
Brugia malayi Subtilase family protein 0.0833 0.8276 1
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0071 0.0243
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0255 0.2397 0.2897
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0174 0.0599
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0084 0.0287
Trichomonas vaginalis glutaminase, putative 0.0305 0.291 1
Brugia malayi Cytochrome P450 family protein 0.002 0.001 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0057 0.0196
Trypanosoma brucei phosphoglycerate kinase 0.007 0.0518 0.2977
Loa Loa (eye worm) hypothetical protein 0.0053 0.0344 0.0415
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0071 0.0243
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Plasmodium falciparum phd finger protein, putative 0.0057 0.0394 0.2262
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0178 0.0822
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0103 0.0103
Schistosoma mansoni hypothetical protein 0.0057 0.0394 0.0476
Brugia malayi glutaminase DH11.1 0.0305 0.291 0.3516
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0113 0.0136
Trypanosoma cruzi phosphoglycerate kinase, putative 0.007 0.0518 0.2977
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0174 0.0599
Treponema pallidum fructose-bisphosphate aldolase 0.0292 0.2779 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0026 0.0071 0.0085
Onchocerca volvulus 0.0036 0.0178 0.0501
Plasmodium falciparum JmjC domain-containing protein, putative 0.0035 0.0161 0.0922
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0159 0.1423 0.1423
Schistosoma mansoni glutamate receptor AMPA 0.0024 0.0056 0.0068
Echinococcus multilocularis membrane bound transcription factor site 1 0.0026 0.0071 0.0071
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0144 0.0824
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0147 0.1301 0.1572
Schistosoma mansoni tar DNA-binding protein 0.0329 0.3155 0.3812
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0274 0.0274
Schistosoma mansoni site-1 peptidase (S08 family) 0.0026 0.0071 0.0085
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0268 0.0324
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0 0.0001
Onchocerca volvulus 0.0237 0.2216 1
Trichomonas vaginalis rotamase, putative 0.0033 0.0144 0.0493
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0494 0.0597
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0178 0.1024
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Loa Loa (eye worm) PHD-finger family protein 0.0057 0.0394 0.0476
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0151 0.0518
Mycobacterium ulcerans glutaminase 0.0305 0.291 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0334 0.0403
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0274 0.0274
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0103 0.0103
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0268 0.0922
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0035 0.0161 0.0924
Loa Loa (eye worm) glutamate receptor 2 0.0024 0.0056 0.0068
Echinococcus granulosus microtubule associated protein 2 0.0696 0.6881 0.6881
Echinococcus granulosus peregrin 0.0061 0.043 0.043
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.2779 0.9551
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0274 0.0331
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0093 0.0757 0.4113
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0025 0.0067 0.0067
Onchocerca volvulus 0.0036 0.0178 0.0501
Brugia malayi Pre-SET motif family protein 0.0208 0.1924 0.2325
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0178 0.0612
Mycobacterium ulcerans lipase LipD 0.0036 0.0178 0.0612
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0 0.0001
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0178 0.0822
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0232 0.2167 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0117 0.0402
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0178 0.0822
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0159 0.1423 0.1423
Echinococcus multilocularis thioredoxin glutathione reductase 0.0037 0.0188 0.0188
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0035 0.0161 0.0922
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0151 0.0518
Echinococcus multilocularis nmda type glutamate receptor 0.0032 0.0135 0.0135
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0029 0.0103 0.0103
Leishmania major trypanothione reductase 0.0037 0.0183 0.1052
Echinococcus multilocularis lysine specific demethylase 6a 0.0035 0.0161 0.0161
Mycobacterium tuberculosis Probable reductase 0.0084 0.0662 0.3055
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0084 0.0662 0.3055
Toxoplasma gondii subtilisin SUB4 0.0026 0.0071 0.0405
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0494 0.2839
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0035 0.0161 0.0161
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0174 0.0599
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.126 0.7127
Toxoplasma gondii subtilisin SUB12 0.0026 0.0071 0.0405
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0255 0.2397 0.2397
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0183 0.0221
Plasmodium falciparum thioredoxin reductase 0.0037 0.0183 0.1051
Loa Loa (eye worm) jmjC domain-containing protein 0.0119 0.1016 0.1228
Plasmodium vivax SET domain protein, putative 0.003 0.0113 0.0646
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0241 0.1384
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.1924 0.2325
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0344 0.0415
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0268 0.1543
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.007 0.0518 0.2977
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0026 0.0071 0.0406
Loa Loa (eye worm) hypothetical protein 0.0035 0.0161 0.0194
Echinococcus granulosus thioredoxin glutathione reductase 0.0037 0.0188 0.0188
Echinococcus multilocularis tar DNA binding protein 0.0329 0.3155 0.3155
Schistosoma mansoni glutamate receptor kainate 0.0024 0.0056 0.0068
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0183 0.0845
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0152 0.0521
Echinococcus granulosus glutamate receptor 2 0.0029 0.0103 0.0103
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0268 0.1542
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0175 0.1004
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0494 0.2839
Onchocerca volvulus 0.0036 0.0178 0.0501
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0161 0.0194
Schistosoma mansoni hypothetical protein 0.0343 0.3296 0.3982
Echinococcus multilocularis Furin 1 0.0026 0.0071 0.0071
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0084 0.0662 0.3543
Onchocerca volvulus 0.0147 0.1301 0.5734
Echinococcus granulosus furin 0.0026 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0071 0.0243
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0178 0.0822
Brugia malayi beta-lactamase family protein 0.0036 0.0178 0.0215
Echinococcus granulosus jumonji domain containing 1A 0.0035 0.0161 0.0161
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.2779 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0201 0.0691
Loa Loa (eye worm) hypothetical protein 0.0036 0.0178 0.0215
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0205 0.0738
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.2779 0.9551
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0113 0.0136
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0159 0.1423 0.1423
Leishmania major phosphoglycerate kinase B, cytosolic 0.019 0.174 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.2779 0.9551
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0178 0.0612
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0178 0.0215
Schistosoma mansoni phosphatidylserine receptor 0.0035 0.0161 0.0194
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Schistosoma mansoni glutamate receptor kainate 0.0024 0.0056 0.0068
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0494 0.0494
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0494 0.0494
Loa Loa (eye worm) hypothetical protein 0.0035 0.0161 0.0194
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0159 0.1423 0.1719
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0 0.0001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0502 0.491 0.5933
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0151 0.0865
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.007 0.0518 0.2977
Schistosoma mansoni protein phosphatase 2C 0.0035 0.0161 0.0194
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0344 0.0415
Toxoplasma gondii subtilisin SUB9 0.0026 0.0071 0.0405
Brugia malayi jmjC domain containing protein 0.0035 0.0161 0.0194
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0159 0.1423 0.1423
Echinococcus granulosus jumonji domain containing protein 0.008 0.0623 0.0623
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0029 0.0103 0.0103
Echinococcus granulosus nmda type glutamate receptor 0.0032 0.0135 0.0135
Brugia malayi beta-lactamase family protein 0.0036 0.0178 0.0215
Toxoplasma gondii subtilisin SUB2 0.0026 0.0071 0.0405
Brugia malayi proprotein convertase 2 0.0026 0.0071 0.0085
Schistosoma mansoni jumonji domain containing protein 0.021 0.194 0.2344
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0026 0.0071 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0057 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0071 0.0243
Echinococcus multilocularis glutamate receptor 2 0.002 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0502 0.491 0.5933
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Brugia malayi Bromodomain containing protein 0.0061 0.043 0.0519
Leishmania major phosphoglycerate kinase C, glycosomal 0.019 0.174 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Brugia malayi RNA recognition motif domain containing protein 0.0329 0.3155 0.3812
Echinococcus multilocularis peregrin 0.0061 0.043 0.043
Brugia malayi Glutamate receptor 2 precursor 0.0024 0.0056 0.0068
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0248 0.2334 0.2334
Echinococcus multilocularis microtubule associated protein 2 0.0696 0.6881 0.6881
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.019 0.174 0.8029
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0274 0.0331
Brugia malayi intermediate filament protein 0.0053 0.0344 0.0415
Loa Loa (eye worm) hypothetical protein 0.0343 0.3296 0.3982
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0026 0.0071 0.0085
Echinococcus granulosus GPCR family 2 0.0159 0.1423 0.1423
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0057 0.0394 0.0476
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0241 0.0828
Toxoplasma gondii subtilisin SUB6 0.0026 0.0071 0.0405
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0 0.0001
Giardia lamblia Phosphoglycerate kinase 0.019 0.174 0.6259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0174 0.0599
Schistosoma mansoni phosphoglycerate kinase 0.019 0.174 0.2102
Loa Loa (eye worm) hypothetical protein 0.019 0.174 0.2102
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0093 0.0757 0.3495
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0026 0.0071 0.0326
Echinococcus multilocularis lamin 0.0053 0.0344 0.0344
Mycobacterium tuberculosis Conserved protein 0.0036 0.0178 0.0822
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0012 0.0014
Echinococcus granulosus JmjC domain containing protein 4 0.0035 0.0161 0.0161
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0025 0.0067 0.0067
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0833 0.8276 1
Onchocerca volvulus Alhambra homolog 0.0057 0.0394 0.1506
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Toxoplasma gondii PHD-finger domain-containing protein 0.0057 0.0394 0.2262
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0026 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0159 0.1423 0.1719
Schistosoma mansoni site-1 peptidase (S08 family) 0.0026 0.0071 0.0085
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Echinococcus granulosus membrane bound transcription factor site 1 0.0026 0.0071 0.0071
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0096 0.0115
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0178 0.0612
Brugia malayi RNA binding protein 0.0329 0.3155 0.3812
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0344 0.0415
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0241 0.1384
Mycobacterium tuberculosis Conserved protein 0.0036 0.0178 0.0822
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Loa Loa (eye worm) glutaminase 2 0.0305 0.291 0.3516
Schistosoma mansoni intermediate filament proteins 0.0053 0.0344 0.0415
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.1236 0.1236
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0 0.0001
Brugia malayi endoprotease bli-4 precursor 0.0026 0.0071 0.0085
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.1277 0.1543
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0081 0.0278
Plasmodium vivax phosphoglycerate kinase, putative 0.019 0.174 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0113 0.0136
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0084 0.0662 0.3055
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0178 0.0822
Loa Loa (eye worm) glutaminase 0.0305 0.291 0.3516
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Echinococcus multilocularis neuroendocrine convertase 2 0.0026 0.0071 0.0071
Loa Loa (eye worm) jmjC domain-containing protein 0.013 0.1127 0.1361
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.1277 0.1543
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0151 0.0518
Brugia malayi glutathione reductase 0.0037 0.0183 0.0221
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0178 0.0612
Leishmania major hypothetical protein, conserved 0.0036 0.0178 0.1024
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.007 0.0518 0.2977
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0178 0.0822
Echinococcus multilocularis JmjC domain containing protein 4 0.0035 0.0161 0.0161
Onchocerca volvulus 0.0053 0.0344 0.1272
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0183 0.1051
Echinococcus multilocularis phd:f box containing protein 0.0035 0.0161 0.0161
Loa Loa (eye worm) endoprotease bli-4 0.0026 0.0071 0.0085
Toxoplasma gondii thioredoxin reductase 0.0037 0.0183 0.1051
Echinococcus granulosus lysine specific demethylase 6a 0.0035 0.0161 0.0161
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0 0.0002
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0268 0.1542
Schistosoma mansoni jumonji/arid domain-containing protein 0.013 0.1127 0.1361
Echinococcus multilocularis tumor protein p63 0.1002 1 1
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0026 0.0071 0.0406
Schistosoma mansoni microtubule-associated protein tau 0.0696 0.6881 0.8314
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0178 0.0178
Giardia lamblia PHD finger protein 15 0.0057 0.0394 0.1417
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0178 0.1024
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0255 0.2397 0.2397
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0494 0.1777
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0268 0.0965
Echinococcus multilocularis jumonji domain containing protein 0.008 0.0623 0.0623
Schistosoma mansoni tar DNA-binding protein 0.0329 0.3155 0.3812
Echinococcus multilocularis GPCR, family 2 0.0159 0.1423 0.1423
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Onchocerca volvulus 0.003 0.0113 0.0195
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0026 0.0071 0.0326
Brugia malayi Latrophilin receptor protein 2 0.0159 0.1423 0.1719
Toxoplasma gondii subtilisin SUB7 0.0026 0.0071 0.0405
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0178 0.0644
Giardia lamblia GTOR 0.0045 0.0268 0.0965
Brugia malayi TAR-binding protein 0.0329 0.3155 0.3812
Echinococcus multilocularis expressed protein 0.0034 0.0152 0.0151
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0268 0.1542
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Brugia malayi beta-lactamase 0.0036 0.0178 0.0215
Schistosoma mansoni jumonji/arid domain-containing protein 0.013 0.1127 0.1361
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.2779 0.9551
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0241 0.1384
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0494 0.2839
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0151 0.0518
Trichomonas vaginalis phosphoglycerate kinase, putative 0.019 0.174 0.5978
Trypanosoma cruzi cytochrome P450, putative 0.002 0.001 0.0059
Echinococcus granulosus phosphoglycerate kinase 1 0.019 0.174 0.1739
Echinococcus granulosus lamin dm0 0.0053 0.0344 0.0344
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0 0.0001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0268 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0084 0.0287
Schistosoma mansoni glutamate receptor NMDA 0.0029 0.0103 0.0124
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.2779 0.9551
Brugia malayi Phosphoglycerate kinase 0.019 0.174 0.2102
Schistosoma mansoni hypothetical protein 0.0159 0.1423 0.1719
Loa Loa (eye worm) hypothetical protein 0.0036 0.0178 0.0215
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0178 0.0822
Trypanosoma brucei phosphoglycerate kinase 0.019 0.174 1
Brugia malayi Thioredoxin reductase 0.0037 0.0183 0.0221
Schistosoma mansoni hypothetical protein 0.0165 0.1484 0.1793
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0035 0.0161 0.0923
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0268 0.0922
Toxoplasma gondii subtilisin SUB10 0.0026 0.0071 0.0405
Toxoplasma gondii subtilisin SUB1 0.0026 0.0071 0.0405
Schistosoma mansoni phd/f-box containing protein 0.0035 0.0161 0.0194
Leishmania major subtilisin-like serine peptidase 0.0026 0.0071 0.0406
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.1019 0.1231
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0113 0.0136
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0161 0.0194
Plasmodium vivax subtilisin-like protease 2, putative 0.0026 0.0071 0.0405
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0178 0.0612
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0069
Trypanosoma brucei phosphoglycerate kinase 0.019 0.174 1
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0029 0.0103 0.0103
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0 0.0001
Schistosoma mansoni glutamate receptor NMDA 0.0024 0.0056 0.0068
Echinococcus granulosus phd:f box containing protein 0.0035 0.0161 0.0161
Trypanosoma cruzi phosphoglycerate kinase, putative 0.019 0.174 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0174 0.0599
Loa Loa (eye worm) glutamate receptor 1 0.0024 0.0056 0.0068
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0241 0.0241
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0026 0.0071 0.0085
Brugia malayi Glutamate receptor 1 precursor 0.0024 0.0056 0.0068
Loa Loa (eye worm) latrophilin receptor protein 2 0.0159 0.1423 0.1719
Trichomonas vaginalis esterase, putative 0.0036 0.0178 0.0612
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0274 0.0331
Trichomonas vaginalis phosphoglycerate kinase, putative 0.019 0.174 0.5978
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0494 0.0597
Trypanosoma brucei trypanothione reductase 0.0037 0.0183 0.1053
Brugia malayi jmjC domain containing protein 0.0035 0.0161 0.0194
Echinococcus multilocularis geminin 0.0165 0.1484 0.1484
Plasmodium falciparum subtilisin-like protease 2 0.0026 0.0071 0.0405
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0178 0.0612
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0161 0.0194
Trichomonas vaginalis rotamase, putative 0.0034 0.0152 0.0521
Loa Loa (eye worm) hypothetical protein 0.0036 0.0178 0.0215
Mycobacterium tuberculosis Conserved protein 0.0036 0.0178 0.0822
Brugia malayi Cytochrome P450 family protein 0.002 0.001 0.0012
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0144 0.0516
Echinococcus multilocularis 0.0026 0.0071 0.0071
Echinococcus granulosus expressed protein 0.0034 0.0152 0.0151
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0268 0.0965
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0329 0.3155 0.3812
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0 0.0001
Brugia malayi latrophilin 2 splice variant baaae 0.0343 0.3296 0.3982
Brugia malayi Phosphoglycerate kinase 0.007 0.0518 0.0626
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Loa Loa (eye worm) RNA binding protein 0.0329 0.3155 0.3812
Echinococcus multilocularis PHD finger protein rhinoceros 0.0057 0.0394 0.0394
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.2779 0.9551
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0026 0.0071 0.0406
Trypanosoma cruzi phosphoglycerate kinase, putative 0.019 0.174 1
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0494 0.284
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0183 0.1052
Schistosoma mansoni cellular tumor antigen P53 0.0147 0.1301 0.1572
Toxoplasma gondii subtilisin SUB5 0.0026 0.0071 0.0405
Schistosoma mansoni glutamate receptor AMPA 0.0024 0.0056 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0057 0.0196
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0026 0.0152
Toxoplasma gondii phosphoglycerate kinase PGKII 0.019 0.174 1
Schistosoma mansoni hypothetical protein 0.0165 0.1484 0.1793
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0151 0.0518
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0144 0.0824
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0178 0.0215
Echinococcus multilocularis lysine specific demethylase 5A 0.013 0.1127 0.1127
Trypanosoma brucei phosphoglycerate kinase, putative 0.007 0.0518 0.2977
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0274 0.0331
Schistosoma mansoni ATP-binding cassette transporter 0.0024 0.0056 0.0068
Echinococcus multilocularis phosphoglycerate kinase 1 0.019 0.174 0.1739
Trypanosoma brucei unspecified product 0.0019 0 0.0001
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0268 0.0268
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Plasmodium falciparum glutathione reductase 0.0037 0.0183 0.1051
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0102 0.0101
Echinococcus multilocularis musashi 0.0053 0.0344 0.0344
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.2779 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0205 0.0738
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0057 0.0196
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0035 0.0161 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0107 0.0368
Plasmodium vivax JmjC domain containing protein 0.0035 0.0161 0.0922
Brugia malayi jmjC domain containing protein 0.013 0.1127 0.1361
Giardia lamblia Fructose-bisphosphate aldolase 0.0292 0.2779 1
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0152 0.0183
Loa Loa (eye worm) hypothetical protein 0.003 0.0113 0.0136
Echinococcus multilocularis glutamate receptor 2 0.0024 0.0056 0.0056
Brugia malayi jmjC domain containing protein 0.0035 0.0161 0.0194
Brugia malayi neuroendocrine convertase 1 precursor 0.0026 0.0071 0.0085
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0026 0.0071 0.0326
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.001 0.0012
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0026 0.0071 0.0243
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0113 0.0113
Echinococcus granulosus glutamate receptor 2 0.002 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0159 0.1423 0.1719
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0268 0.0324
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0026 0.0071 0.0243
Loa Loa (eye worm) subtilase 0.0833 0.8276 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.2779 0.9551
Echinococcus multilocularis glutamate receptor 2 0.0029 0.0103 0.0103
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.019 0.174 0.5
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0144 0.0823
Treponema pallidum phosphoglycerate kinase 0.019 0.174 0.62
Echinococcus granulosus tar DNA binding protein 0.0329 0.3155 0.3155
Brugia malayi Pre-SET motif family protein 0.003 0.0113 0.0136
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0026 0.0071 0.0243
Trypanosoma brucei cytochrome P450, putative 0.002 0.001 0.0059
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0144 0.0825
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0 0.0001
Brugia malayi jmjC domain containing protein 0.0035 0.0161 0.0194
Trypanosoma cruzi cytochrome P450, putative 0.002 0.001 0.0059
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0026 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0026 0.0071 0.0085
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0205 0.1177
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0274 0.0274
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.001 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0329 0.3155 0.3812
Echinococcus granulosus lysine specific demethylase 5A 0.013 0.1127 0.1127
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0178 0.0178
Toxoplasma gondii subtilisin SUB11 0.0026 0.0071 0.0405
Toxoplasma gondii phosphoglycerate kinase PGKI 0.019 0.174 1
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0029 0.0103 0.0103
Plasmodium falciparum phosphoglycerate kinase 0.019 0.174 1
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0113 0.0113
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0502 0.491 0.5933
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0 0.0001
Trypanosoma cruzi subtilisin peptidase 0.0026 0.0071 0.0406
Loa Loa (eye worm) hypothetical protein 0.0026 0.0071 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0268 0.0922
Mycobacterium ulcerans beta-lactamase 0.0036 0.0178 0.0612
Echinococcus granulosus intermediate filament protein 0.0053 0.0344 0.0344
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0178 0.1025
Plasmodium vivax subtilisin-like serine protease, putative 0.0026 0.0071 0.0405
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0241 0.0828
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0268 0.1543
Schistosoma mansoni hypothetical protein 0.0159 0.1423 0.1719
Brugia malayi MH2 domain containing protein 0.0119 0.1019 0.1231
Echinococcus granulosus geminin 0.0165 0.1484 0.1484
Mycobacterium leprae Probable lipase LipE 0.0036 0.0178 0.0644
Plasmodium falciparum subtilisin-like protease 3 0.0026 0.0071 0.0405
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.126 0.433
Loa Loa (eye worm) hypothetical protein 0.0024 0.0057 0.0069
Loa Loa (eye worm) hypothetical protein 0.0036 0.0178 0.0215
Chlamydia trachomatis phosphoglycerate kinase 0.019 0.174 1
Plasmodium vivax subtilisin-like protease 1 0.0026 0.0071 0.0405
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0023 0.0044 0.02
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0093 0.0757 0.3495
Toxoplasma gondii PHD-finger domain-containing protein 0.0057 0.0394 0.2262
Brugia malayi jmjC domain containing protein 0.0248 0.2334 0.282

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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