Detailed information for compound 1161189

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 341.47 | Formula: C19H23N3OS
  • H donors: 0 H acceptors: 2 LogP: 2.25 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1CCC2(N1Cc1ccccc1)CCN(CC2)Cc1nccs1
  • InChi: 1S/C19H23N3OS/c23-18-6-7-19(22(18)14-16-4-2-1-3-5-16)8-11-21(12-9-19)15-17-20-10-13-24-17/h1-5,10,13H,6-9,11-12,14-15H2
  • InChiKey: KOWWOVBMLNQQND-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0253 0.0844
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0814 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0601 0.4064
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0814 1
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0104 0.0324
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0269 0.0897
Loa Loa (eye worm) hypothetical protein 0.002 0.0104 0.0324
Echinococcus granulosus pyruvate kinase 0.0017 0.0071 0.0177
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.029 0.029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0418 0.2803
Trichomonas vaginalis mercuric reductase, putative 0.0046 0.0418 0.4096
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0104 0.0209
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0104 0.0324
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0071 0.0419
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0104 0.0324
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0046 0.0418 0.2803
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0286 0.0708
Schistosoma mansoni tar DNA-binding protein 0.0251 0.2888 0.5804
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0012 0.0011 0.0011
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0082 0.0247
Mycobacterium tuberculosis Probable reductase 0.0303 0.3516 0.8958
Echinococcus multilocularis tar DNA binding protein 0.0251 0.2888 0.2888
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.032 0.385
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1006 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0046 0.0418 0.1417
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0269 0.1776
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0104 0.0324
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.032 0.2127
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0303 0.3516 0.8958
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0269 0.1776
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.032 0.3108
Loa Loa (eye worm) glutathione reductase 0.0133 0.1465 0.5053
Treponema pallidum NADH oxidase 0.0046 0.0418 0.5074
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.032 0.3108
Onchocerca volvulus Serine\/threonine kinase homolog 0.0095 0.1006 0.5887
Echinococcus granulosus tumor protein p63 0.0344 0.4004 0.9933
Mycobacterium tuberculosis Conserved protein 0.0035 0.0286 0.0703
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.032 0.0794
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0046 0.0418 0.2803
Brugia malayi nuclear receptor NHR-88 0.002 0.0104 0.0324
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0354 0.0354
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0046 0.0418 0.2803
Chlamydia trachomatis pyruvate kinase 0.0034 0.0269 0.3214
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0814 0.0814
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0104 0.0324
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0104 0.0324
Giardia lamblia Pyruvate kinase 0.0017 0.0071 0.0612
Schistosoma mansoni hypothetical protein 0.0346 0.4031 0.81
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0046 0.0418 0.2803
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0469 0.0943
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0251 0.0615
Echinococcus granulosus glutamate synthase 0.0012 0.0011 0.0026
Schistosoma mansoni hypothetical protein 0.0012 0.0011 0.0021
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0046 0.0418 0.2803
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0168 0.1084
Brugia malayi jmjC domain containing protein 0.0096 0.1018 0.3502
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0418 0.2803
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0012 0.0011 0.0026
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0104 0.0258
Entamoeba histolytica hypothetical protein 0.0035 0.0282 0.2728
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0296 0.2873
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0601 0.7355
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0486 0.1207
Brugia malayi hypothetical protein 0.0239 0.2738 0.9479
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0229 0.2625 0.5274
Brugia malayi PHD-finger family protein 0.0029 0.0216 0.0714
Schistosoma mansoni hypothetical protein 0.0035 0.0282 0.0567
Echinococcus granulosus cpg binding protein 0.003 0.022 0.0545
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1006 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.1006 0.6844
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1006 1
Loa Loa (eye worm) thioredoxin reductase 0.0133 0.1465 0.5053
Brugia malayi beta-lactamase 0.0035 0.0286 0.0956
Loa Loa (eye worm) hypothetical protein 0.005 0.0468 0.1589
Loa Loa (eye worm) hypothetical protein 0.0035 0.0286 0.0956
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0502 0.3382
Onchocerca volvulus 0.005 0.0469 0.2714
Leishmania major pyruvate kinase 0.0034 0.0269 0.1776
Brugia malayi RNA recognition motif domain containing protein 0.0251 0.2888 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0216 0.1412
Loa Loa (eye worm) hypothetical protein 0.002 0.0104 0.0324
Brugia malayi beta-lactamase family protein 0.0035 0.0286 0.0956
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0601 0.1492
Leishmania major pyruvate kinase 0.0034 0.0269 0.1776
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0046 0.0418 0.5074
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0104 0.0209
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0104 0.0258
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.045 0.1526
Giardia lamblia Kinase, PLK 0.0095 0.1006 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0104 0.0324
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0168 0.1084
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.1096 0.3773
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0269 0.0897
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0286 0.0703
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0296 0.2873
Plasmodium falciparum pyruvate kinase 0.0034 0.0269 0.1776
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0012 0.0011 0.0011
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0286 0.0286
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.032 0.1075
Loa Loa (eye worm) TAR-binding protein 0.0251 0.2888 1
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0104 0.0324
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0071 0.0419
Schistosoma mansoni ferritin 0.0017 0.0066 0.0132
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0354 0.0878
Echinococcus granulosus pyruvate kinase 0.0017 0.0071 0.0177
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0601 0.7355
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0418 0.2803
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0062 0.0125
Echinococcus granulosus survival motor neuron protein 1 0.0239 0.2738 0.6793
Schistosoma mansoni hypothetical protein 0.0049 0.045 0.0904
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0269 0.1528
Echinococcus granulosus expressed protein 0.0017 0.0066 0.0164
Schistosoma mansoni ap endonuclease 0.0038 0.032 0.0643
Schistosoma mansoni pyruvate kinase 0.0034 0.0269 0.054
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0706 0.2417
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0071 0.0419
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0286 0.1891
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0269 0.2595
Toxoplasma gondii NADPH-glutathione reductase 0.0046 0.0418 0.2803
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0012 0.0011 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0104 0.0324
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0168 0.1084
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0601 0.4064
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0309 0.1038
Schistosoma mansoni hypothetical protein 0.0346 0.4031 0.81
Loa Loa (eye worm) hypothetical protein 0.0035 0.0286 0.0956
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0253 0.0253
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0286 0.0703
Schistosoma mansoni hypothetical protein 0.0032 0.0253 0.0509
Onchocerca volvulus 0.0035 0.0286 0.1627
Schistosoma mansoni tar DNA-binding protein 0.0251 0.2888 0.5804
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0104 0.0209
Schistosoma mansoni ferritin 0.0017 0.0066 0.0132
Onchocerca volvulus 0.0049 0.045 0.2597
Echinococcus multilocularis survival motor neuron protein 1 0.0239 0.2738 0.2738
Schistosoma mansoni sulfide quinone reductase 0.0012 0.0011 0.0021
Loa Loa (eye worm) hypothetical protein 0.007 0.0706 0.2417
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0591 0.2018
Brugia malayi TAR-binding protein 0.0251 0.2888 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.032 0.2127
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0269 0.066
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0104 0.0324
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0104 0.0209
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0104 0.0324
Echinococcus multilocularis pyruvate kinase 0.0017 0.0071 0.0071
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0296 0.0735
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0286 0.0703
Brugia malayi Bromodomain containing protein 0.0029 0.0216 0.0714
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0269 0.1528
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0286 0.0703
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0146 0.0471
Brugia malayi hypothetical protein 0.0025 0.0168 0.0548
Trichomonas vaginalis glutathione reductase, putative 0.0046 0.0418 0.4096
Brugia malayi hypothetical protein 0.0016 0.006 0.0172
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0429 0.4203
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.032 0.2127
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0814 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0303 0.3516 0.8958
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0066 0.0141
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0296 0.3558
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0418 0.2803
Brugia malayi nuclear hormone receptor 0.002 0.0104 0.0324
Schistosoma mansoni nuclear hormone receptor 0.002 0.0104 0.0209
Loa Loa (eye worm) hypothetical protein 0.0035 0.0286 0.0956
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0814 0.5525
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0104 0.0104
Echinococcus multilocularis ferritin 0.0017 0.0066 0.0066
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0012 0.0011 0.0011
Brugia malayi Thioredoxin reductase 0.0133 0.1465 0.5053
Toxoplasma gondii ABC1 family protein 0.0035 0.0286 0.1891
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0104 0.0324
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0104 0.0209
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0337 0.3924 1
Echinococcus multilocularis pyruvate kinase 0.0017 0.0071 0.0071
Brugia malayi RNA binding protein 0.0251 0.2888 1
Schistosoma mansoni inositol monophosphatase 0.0036 0.0296 0.0596
Schistosoma mansoni cpg binding protein 0.003 0.022 0.0442
Echinococcus multilocularis pyruvate kinase 0.0034 0.0269 0.0269
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0046 0.0418 0.5074
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0046 0.0418 0.5074
Plasmodium falciparum glutathione reductase 0.0133 0.1465 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0286 0.0956
Echinococcus multilocularis cpg binding protein 0.003 0.022 0.022
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0095 0.1006 0.1006
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0046 0.0418 0.2803
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0012 0.0011 0.0011
Brugia malayi ecdysteroid receptor 0.002 0.0104 0.0324
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0296 0.1966
Schistosoma mansoni thyroid hormone receptor 0.002 0.0104 0.0209
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0104 0.0104
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0133 0.1465 0.3716
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0337 0.3924 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0095 0.1006 0.3459
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.032 0.3108
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0046 0.0418 0.1042
Loa Loa (eye worm) hypothetical protein 0.0029 0.0216 0.0714
Echinococcus granulosus peregrin 0.0029 0.0216 0.0536
Schistosoma mansoni tar DNA-binding protein 0.0251 0.2888 0.5804
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0286 0.0703
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0191 0.124
Plasmodium falciparum thioredoxin reductase 0.0133 0.1465 1
Loa Loa (eye worm) inositol-1 0.0036 0.0296 0.0994
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0066 0.0141
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0296 0.1966
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0601 0.1209
Loa Loa (eye worm) hypothetical protein 0.0153 0.1701 0.5875
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0216 0.0216
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0286 0.0956
Echinococcus granulosus tar DNA binding protein 0.0251 0.2888 0.7165
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0486 0.0486
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0104 0.0104
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0168 0.1084
Schistosoma mansoni hypothetical protein 0.0032 0.0253 0.0509
Plasmodium vivax thioredoxin reductase, putative 0.0133 0.1465 1
Schistosoma mansoni hypothetical protein 0.0032 0.0253 0.0509
Trichomonas vaginalis ferritin, putative 0.0017 0.0066 0.0556
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0269 0.3214
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0104 0.0104
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0286 0.3423
Loa Loa (eye worm) hypothetical protein 0.002 0.0104 0.0324
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.1006 0.6844
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0286 0.0574
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.1096 0.3773
Loa Loa (eye worm) hypothetical protein 0.0023 0.0146 0.0471
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0229 0.2625 0.9085
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0286 0.0574
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0814 0.2053
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0104 0.0258
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0104 0.0324
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0034 0.0271 0.0905
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0814 0.5525
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0104 0.0104
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0286 0.2763
Echinococcus granulosus geminin 0.0346 0.4031 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0296 0.1966
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0168 0.1084
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0229 0.2625 0.9085
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0282 0.0567
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0046 0.0418 0.1037
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0296 0.2873
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0104 0.0258
Schistosoma mansoni glutamate synthase 0.0012 0.0011 0.0021
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0229 0.2625 0.6512
Loa Loa (eye worm) hypothetical protein 0.0034 0.0269 0.0897
Schistosoma mansoni disulfide oxidoreductase 0.0012 0.0011 0.0021
Brugia malayi Probable ClpP-like protease 0.0079 0.0814 0.2792
Schistosoma mansoni sulfide quinone reductase 0.0012 0.0011 0.0021
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0814 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0095 0.1006 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0253 0.0629
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0046 0.0418 0.2803
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0104 0.0324
Schistosoma mansoni glutamate synthase 0.0012 0.0011 0.0021
Brugia malayi beta-lactamase family protein 0.0035 0.0286 0.0956
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0104 0.0209
Toxoplasma gondii exonuclease III APE 0.0038 0.032 0.2127
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0046 0.0418 0.2803
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0012 0.0011 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1006 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0046 0.0418 0.2803
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0104 0.0324
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0286 0.1891
Mycobacterium ulcerans hypothetical protein 0.0035 0.0286 0.3423
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0104 0.0104
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0046 0.0418 0.5074
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0017 0.0066 0.0141
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0046 0.0418 0.2803
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0012 0.0011 0.0011
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0066 0.0689
Echinococcus multilocularis pyruvate kinase 0.0017 0.0071 0.0071
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.1096 0.3773
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0253 0.0844
Mycobacterium ulcerans lipase LipD 0.0035 0.0286 0.3423
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0216 0.1412
Mycobacterium ulcerans beta-lactamase 0.0035 0.0286 0.3423
Trichomonas vaginalis esterase, putative 0.0035 0.0286 0.2763
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0046 0.0418 0.2803
Echinococcus granulosus pyruvate kinase 0.0017 0.0071 0.0177
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.032 0.079
Schistosoma mansoni cpg binding protein 0.0028 0.0201 0.0403
Schistosoma mansoni ap endonuclease 0.0038 0.032 0.0643
Loa Loa (eye worm) hypothetical protein 0.0239 0.2738 0.9479
Schistosoma mansoni thyroid hormone receptor 0.002 0.0104 0.0209
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.032 0.032
Schistosoma mansoni tar DNA-binding protein 0.0251 0.2888 0.5804
Brugia malayi CXXC zinc finger family protein 0.0028 0.0201 0.066
Schistosoma mansoni hypothetical protein 0.0032 0.0253 0.0509
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0286 0.0703
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0781 0.1569
Echinococcus granulosus pyruvate kinase 0.0034 0.0269 0.0667
Giardia lamblia PHD finger protein 15 0.0029 0.0216 0.2063
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0046 0.0418 0.5074
Trypanosoma cruzi trypanothione reductase, putative 0.0133 0.1465 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0296 0.1966
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0104 0.0104
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0095 0.1006 0.3459
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0286 0.0703
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0201 0.066
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0229 0.2625 0.2625
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0104 0.0324
Loa Loa (eye worm) beta-lactamase 0.0035 0.0286 0.0956
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0046 0.0418 0.5074
Mycobacterium tuberculosis Probable dehydrogenase 0.0303 0.3516 0.8958
Mycobacterium leprae Probable lipase LipE 0.0035 0.0286 0.0703
Leishmania major trypanothione reductase 0.0133 0.1465 1
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0191 0.2244
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0104 0.0258
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0814 0.5525
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0012 0.0011 0.0026
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0096 0.1018 0.2526
Echinococcus multilocularis pyruvate kinase 0.0034 0.0269 0.0269
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0286 0.2763
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0046 0.0418 0.0418
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0309 0.0767
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0303 0.3516 0.8958
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.032 0.385
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0229 0.2625 0.6512
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0418 0.2803
Echinococcus multilocularis tumor protein p63 0.0344 0.4004 0.4004
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0251 0.2888 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0296 0.3558
Loa Loa (eye worm) hypothetical protein 0.002 0.0104 0.0324
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0104 0.0324
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0216 0.0434
Echinococcus granulosus pyruvate kinase 0.0034 0.0269 0.0667
Loa Loa (eye worm) hypothetical protein 0.0035 0.0286 0.0956
Echinococcus multilocularis thioredoxin glutathione reductase 0.0133 0.1471 0.1471
Loa Loa (eye worm) hypothetical protein 0.005 0.0469 0.1594
Plasmodium falciparum thioredoxin reductase 0.0046 0.0418 0.2803
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0104 0.0258
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0012 0.0011 0.0026
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0104 0.0324
Mycobacterium tuberculosis Conserved protein 0.0035 0.0286 0.0703
Toxoplasma gondii hypothetical protein 0.0027 0.0191 0.124
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0253 0.0629
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0046 0.0418 0.084
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0601 0.7355
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.032 0.2127
Echinococcus granulosus ferritin 0.0017 0.0066 0.0164
Onchocerca volvulus 0.002 0.0104 0.0552
Schistosoma mansoni survival motor neuron protein 0.0049 0.045 0.0904
Leishmania major hypothetical protein, conserved 0.0035 0.0286 0.1891
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0104 0.0258
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0429 0.4203
Trypanosoma brucei trypanothione reductase 0.0133 0.1465 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0296 0.2873
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1006 1
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.1006 0.2021
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0269 0.1776
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0216 0.0714
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0269 0.2595
Onchocerca volvulus 0.0035 0.0286 0.1627
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0814 1
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0066 0.0689
Onchocerca volvulus 0.0028 0.0201 0.1124
Plasmodium falciparum phd finger protein, putative 0.0029 0.0216 0.1412
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0269 0.1528
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0601 0.0601
Onchocerca volvulus 0.0035 0.0286 0.1627
Brugia malayi glutathione reductase 0.0133 0.1465 0.5053
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0601 0.1209
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0104 0.0552
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0104 0.0324
Schistosoma mansoni cpg binding protein 0.003 0.022 0.0442
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0269 0.0897
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0486 0.1216
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0229 0.2625 0.2625
Echinococcus multilocularis pyruvate kinase 0.0027 0.0183 0.0183
Schistosoma mansoni glutamate synthase 0.0012 0.0011 0.0021
Schistosoma mansoni hypothetical protein 0.0029 0.0216 0.0434
Entamoeba histolytica hypothetical protein 0.0035 0.0282 0.2728
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0229 0.2625 0.5274
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.032 0.2127
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0046 0.0418 0.2803
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0253 0.0253
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0286 0.2763
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0286 0.3423
Echinococcus granulosus GPCR family 2 0.0032 0.0253 0.0629
Schistosoma mansoni ferritin light chain 0.0017 0.0066 0.0132
Echinococcus multilocularis glutamate synthase 0.0012 0.0011 0.0011
Brugia malayi jmjC domain containing protein 0.0037 0.0309 0.1038
Giardia lamblia NADH oxidase lateral transfer candidate 0.0046 0.0418 0.4096
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0012 0.0011 0.0026
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.032 0.2127
Loa Loa (eye worm) hypothetical protein 0.0102 0.1096 0.3773
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0146 0.1362
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0104 0.0324
Brugia malayi hypothetical protein 0.0153 0.1701 0.5875
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0168 0.1084
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0303 0.3516 0.8958
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0286 0.2763
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1006 1
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0216 0.0536
Schistosoma mansoni pyruvate kinase 0.0034 0.0269 0.054
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0104 0.0324
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0168 0.1084
Schistosoma mansoni apoferritin-2 0.0017 0.0066 0.0132
Schistosoma mansoni ferritin light chain 0.0017 0.0066 0.0132
Leishmania major hypothetical protein, conserved 0.0025 0.0168 0.1084
Loa Loa (eye worm) hypothetical protein 0.002 0.0104 0.0324
Loa Loa (eye worm) hypothetical protein 0.002 0.0104 0.0324
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0296 0.0296
Plasmodium vivax glutathione reductase, putative 0.0133 0.1465 1
Echinococcus multilocularis geminin 0.0346 0.4031 0.4031
Echinococcus multilocularis expressed protein 0.0017 0.0066 0.0066
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0814 0.5525
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0309 0.0622
Schistosoma mansoni hypothetical protein 0.007 0.0706 0.1419
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.0579 0.1163
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0269 0.066
Schistosoma mansoni tar DNA-binding protein 0.0251 0.2888 0.5804
Schistosoma mansoni pyruvate kinase 0.0017 0.0071 0.0144
Schistosoma mansoni ferritin 0.0017 0.0066 0.0132
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0104 0.0258
Schistosoma mansoni kinase 0.0048 0.0444 0.0892
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.032 0.1075
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0303 0.3516 0.8958
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0251 0.0615
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0095 0.1006 0.2495
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0017 0.0066 0.0689
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0229 0.2625 0.5274
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0034 0.0271 0.0905
Giardia lamblia Pyruvate kinase 0.0034 0.0269 0.2595
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0104 0.0209
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0104 0.0324
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0216 0.1412
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0012 0.0011 0.0026
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0104 0.0104
Loa Loa (eye worm) RNA binding protein 0.0251 0.2888 1
Entamoeba histolytica hypothetical protein 0.0035 0.0282 0.2728
Onchocerca volvulus Alhambra homolog 0.0029 0.0216 0.1215
Brugia malayi steroid hormone receptor 0.002 0.0104 0.0324
Entamoeba histolytica hypothetical protein 0.0035 0.0282 0.2728
Loa Loa (eye worm) hypothetical protein 0.0032 0.0253 0.0844
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0282 0.0282
Mycobacterium tuberculosis Conserved protein 0.0035 0.0286 0.0703
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0418 0.2803
Echinococcus granulosus FTZ F1 alpha 0.002 0.0104 0.0258
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0269 0.1776
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0296 0.1966
Echinococcus multilocularis GPCR, family 2 0.0032 0.0253 0.0253
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0046 0.0418 0.2803
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0046 0.0418 0.2803
Echinococcus multilocularis peregrin 0.0029 0.0216 0.0216
Mycobacterium tuberculosis Probable oxidoreductase 0.0337 0.3924 1
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0814 0.1636
Schistosoma mansoni ferritin 0.0017 0.0066 0.0132
Treponema pallidum bacterioferrin (TpF1) 0.0017 0.0066 0.0689
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0269 0.0897
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0309 0.0622
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0269 0.0897
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0104 0.0104
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0104 0.0209
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.032 0.385
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0269 0.1776
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0286 0.0956
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.032 0.3108
Plasmodium falciparum glutathione reductase 0.0046 0.0418 0.2803
Loa Loa (eye worm) hypothetical protein 0.0025 0.0168 0.0548
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0191 0.0461
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0286 0.1891
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0224 0.2561 0.6518
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0096 0.1018 0.1018
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0095 0.1006 0.6844
Loa Loa (eye worm) hypothetical protein 0.0079 0.0814 0.2792
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0104 0.0552
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0286 0.2763
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0282 0.07
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0286 0.1891
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0286 0.0703
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0104 0.0324
Onchocerca volvulus 0.0153 0.1701 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0337 0.3924 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0104 0.0324
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1006 1
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0269 0.1776
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0486 0.1216
Schistosoma mansoni coup transcription factor 0.002 0.0104 0.0209
Schistosoma mansoni apoferritin-2 0.0017 0.0066 0.0132
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0104 0.0209
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0046 0.0418 0.2803
Toxoplasma gondii thioredoxin reductase 0.0133 0.1465 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0133 0.1471 0.3649
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0104 0.0552
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0814 0.2019
Schistosoma mansoni inositol monophosphatase 0.0036 0.0296 0.0596
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0486 0.1216
Brugia malayi Inositol-1 0.0036 0.0296 0.0994
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0814 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0253 0.0844
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0046 0.0418 0.2803
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0104 0.0324
Brugia malayi hypothetical protein 0.0035 0.0282 0.0944
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0601 0.151
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0191 0.124
Trypanosoma brucei polo-like protein kinase 0.0095 0.1006 0.6844
Loa Loa (eye worm) hypothetical protein 0.0035 0.0286 0.0956
Loa Loa (eye worm) hypothetical protein 0.002 0.0104 0.0324

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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