Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6547 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.0043 | 1 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.003 | 0.4775 | 0.4775 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.003 | 0.4775 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6547 | 1 |
Brugia malayi | hypothetical protein | 0.0035 | 0.6547 | 0.6547 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.6547 | 0.6547 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6547 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0043 | 1 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.6547 | 0.6547 |
Leishmania major | DNA polymerase eta, putative | 0.0043 | 1 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0043 | 1 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.6547 | 0.6547 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.6547 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0 | 0.5 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0043 | 1 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.6547 | 0.6547 |
Echinococcus multilocularis | dna polymerase eta | 0.0043 | 1 | 1 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.003 | 0.4775 | 0.4775 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.