Detailed information for compound 116222

Basic information

Technical information
  • TDR Targets ID: 116222
  • Name: (2R)-N-[(2S)-1-(dimethylamino)-3-(1H-indol-3- yl)-1-oxopropan-2-yl]-N'-hydroxy-2-(2-methylp ropyl)butanediamide
  • MW: 402.487 | Formula: C21H30N4O4
  • H donors: 4 H acceptors: 4 LogP: 1.6 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: ONC(=O)C[C@H](C(=O)N[C@H](C(=O)N(C)C)Cc1c[nH]c2c1cccc2)CC(C)C
  • InChi: 1S/C21H30N4O4/c1-13(2)9-14(11-19(26)24-29)20(27)23-18(21(28)25(3)4)10-15-12-22-17-8-6-5-7-16(15)17/h5-8,12-14,18,22,29H,9-11H2,1-4H3,(H,23,27)(H,24,26)/t14-,18+/m1/s1
  • InChiKey: VWIDRIAWTQJPLN-KDOFPFPSSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R)-N-[(1S)-2-(dimethylamino)-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]-2-[2-(hydroxyamino)-2-oxo-ethyl]-4-methyl-pentanamide
  • (2R)-N-[(1S)-2-(dimethylamino)-1-(1H-indol-3-ylmethyl)-2-oxoethyl]-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanamide
  • (2R)-N-[(2S)-1-(dimethylamino)-3-(1H-indol-3-yl)-1-oxo-propan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide
  • (2R)-N-[(1S)-2-(dimethylamino)-1-(1H-indol-3-ylmethyl)-2-keto-ethyl]-2-[2-(hydroxyamino)-2-keto-ethyl]-4-methyl-valeramide
  • (2R)-N-[(2S)-1-dimethylamino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide
  • (2R)-N-[(1S)-2-dimethylamino-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]-2-[2-(hydroxyamino)-2-oxo-ethyl]-4-methyl-pentanamide
  • (2R)-N-[(1S)-2-dimethylamino-1-(1H-indol-3-ylmethyl)-2-oxoethyl]-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanamide
  • (2R)-N-[(1S)-2-dimethylamino-1-(1H-indol-3-ylmethyl)-2-keto-ethyl]-2-[2-(hydroxyamino)-2-keto-ethyl]-4-methyl-valeramide
  • (2R)-N-[(2S)-1-dimethylamino-3-(1H-indol-3-yl)-1-oxo-propan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) Starlite/ChEMBL References
Homo sapiens matrix metallopeptidase 8 (neutrophil collagenase) Starlite/ChEMBL References
Homo sapiens matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus matrix metallopeptidase 7 M10 family matrix metallopeptidase 8 (neutrophil collagenase) 467 aa 467 aa 33.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0033 0.0062 0.0049
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0264 0.1096 0.1083
Trichomonas vaginalis adenylate cyclase, putative 0.0033 0.0062 0.0049
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0033 0.0062 0.0049
Mycobacterium leprae Conserved hypothetical protein 0.0047 0.0127 0.053
Echinococcus multilocularis expressed protein 0.0022 0.0013 0.0004
Loa Loa (eye worm) intermediate filament protein 0.0032 0.0056 0.0052
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0056 0.0164 0.0155
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0052 0.0146 0.0137
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Giardia lamblia GTOR 0.0052 0.0146 0.0133
Plasmodium falciparum splicing factor 3B subunit 3, putative 0.0032 0.0058 0.0045
Loa Loa (eye worm) ctsf protein 0.0278 0.1157 0.1154
Echinococcus multilocularis G-protein coupled receptor, putative 0.0099 0.036 0.0351
Loa Loa (eye worm) hypothetical protein 0.0032 0.0056 0.0052
Loa Loa (eye worm) fibroinase 0.0278 0.1157 0.1154
Loa Loa (eye worm) hypothetical protein 0.0031 0.0054 0.0049
Schistosoma mansoni cpg binding protein 0.0034 0.0066 0.0053
Brugia malayi AKH receptor 0.0099 0.036 0.0348
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0039 0.0026
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0051 0.0144 0.0131
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0033 0.0062 0.0049
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Onchocerca volvulus 0.0099 0.036 0.0814
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.083 0.0819
Echinococcus multilocularis cysteine protease 0.0278 0.1157 0.1149
Giardia lamblia Cysteine protease 0.0051 0.0144 0.0131
Schistosoma mansoni myosin xvIII 0.0099 0.036 0.0348
Schistosoma mansoni hypothetical protein 0.0317 0.1334 0.1323
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0047 0.0127 0.0114
Mycobacterium tuberculosis Conserved protein 0.0047 0.0127 0.0743
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0024 0.002 0.0008
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0047 0.0127 0.0118
Echinococcus multilocularis serotonin receptor 0.0099 0.036 0.0351
Brugia malayi regulator of G-protein signaling rgs-7 0.0022 0.0015 0.0003
Plasmodium falciparum serine repeat antigen 7 0.0051 0.0144 0.0131
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0104 0.0591
Toxoplasma gondii preprocathepsin c precursor, putative 0.0051 0.0144 0.0995
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0024 0.002 0.0012
Trichomonas vaginalis adenylate cyclase, putative 0.0033 0.0062 0.0049
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0047 0.0127 0.0114
Echinococcus granulosus agrin 0.0022 0.0013 0.0004
Schistosoma mansoni lamin 0.0032 0.0056 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0056 0.0164 0.0151
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0264 0.1096 0.1083
Brugia malayi cathepsin F-like cysteine proteinase 0.0051 0.0144 0.0132
Mycobacterium ulcerans lipase LipD 0.0042 0.0104 0.0091
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0031 0.0051 0.0043
Echinococcus multilocularis neuropeptide receptor 0.0099 0.036 0.0351
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0099 0.036 0.0351
Trichomonas vaginalis adenylate cyclase, putative 0.0033 0.0062 0.0049
Echinococcus multilocularis neuropeptide receptor 0.0099 0.036 0.0351
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0951 0.4172 0.4167
Brugia malayi nuclear receptor NHR-88 0.0026 0.0032 0.002
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.2254 1 1
Trypanosoma cruzi heat shock protein 85, putative 0.003 0.0048 0.0035
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0278 0.1157 0.1147
Entamoeba histolytica hypothetical protein 0.0051 0.0144 0.0131
Brugia malayi G-protein coupled receptor 0.0099 0.036 0.0348
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0104 0.0591
Brugia malayi Cathepsin L-like precursor 0.0186 0.0746 0.0735
Entamoeba histolytica cysteine protease, putative 0.0143 0.0555 0.0542
Schistosoma mansoni hypothetical protein 0.0394 0.1675 0.1665
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Trichomonas vaginalis adenylate cyclase, putative 0.0033 0.0062 0.0049
Brugia malayi A-kinase anchor protein 10, precursor 0.0022 0.0015 0.0003
Trypanosoma cruzi cruzipain precursor, putative 0.0092 0.0326 0.0313
Schistosoma mansoni hypothetical protein 0.0062 0.0194 0.0182
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0127 0.0114
Echinococcus granulosus subfamily M12B unassigned peptidase 0.025 0.1033 0.1025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.036 0.0351
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0092 0.0326 0.0321
Trichomonas vaginalis fk506-binding protein, putative 0.0317 0.1334 0.1324
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0069 0.0224 0.0219
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0278 0.1157 0.1147
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0144 0.0131
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0099 0.036 0.0348
Trichomonas vaginalis fk506-binding protein, putative 0.2251 0.9988 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0278 0.1157 0.1149
Schistosoma mansoni vesicular amine transporter 0.0024 0.002 0.0008
Giardia lamblia Hypothetical protein 0.0051 0.0144 0.0131
Echinococcus granulosus two pore calcium channel protein 1 0.0024 0.002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Entamoeba histolytica cysteine protease, putative 0.0143 0.0555 0.0542
Leishmania major DNA polymerase kappa, putative 0.0024 0.0023 0.001
Plasmodium vivax serine-repeat antigen (SERA) 0.0051 0.0144 0.0131
Plasmodium falciparum serine repeat antigen 3 0.0051 0.0144 0.0131
Brugia malayi ecdysone receptor 0.0026 0.0032 0.002
Brugia malayi hypothetical protein 0.0024 0.002 0.0008
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0051 0.0144 0.0131
Echinococcus multilocularis lamin dm0 0.0032 0.0056 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0065 0.0051
Giardia lamblia Grp94/Hsp90 0.003 0.0048 0.0034
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0027
Echinococcus granulosus cysteine protease 0.0143 0.0555 0.0546
Echinococcus granulosus lamin 0.0032 0.0056 0.0048
Mycobacterium ulcerans DNA polymerase IV 0.0047 0.0126 0.0113
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0047 0.0126 0.0113
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0099 0.036 0.0348
Trichomonas vaginalis hypothetical protein 0.0033 0.0062 0.0049
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0015 0.0007
Leishmania major hypothetical protein, unknown function 0.0047 0.0127 0.0114
Brugia malayi nuclear receptor NHR-67 0.0026 0.0032 0.002
Giardia lamblia Cysteine protease 0.0051 0.0144 0.0131
Echinococcus multilocularis dna polymerase kappa 0.0047 0.0126 0.0117
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0051 0.0144 0.0131
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0015 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0126 0.0126
Brugia malayi beta-lactamase family protein 0.0042 0.0104 0.0091
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0333 0.1404 0.1406
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0015 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0053 0.0039
Echinococcus granulosus adam 17 protease 0.0317 0.1335 0.1327
Echinococcus granulosus rhodopsin orphan GPCR 0.0099 0.036 0.0351
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.002 0.0012
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0104 0.0091
Mycobacterium ulcerans transcriptional regulatory protein 0.0047 0.0127 0.0114
Plasmodium falciparum cGMP-dependent protein kinase 0.0047 0.0127 0.0114
Echinococcus granulosus shaker cognate 0.0024 0.002 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0047 0.0127 0.0114
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0047 0.0127 0.0118
Echinococcus multilocularis two pore calcium channel protein 2 0.0024 0.002 0.0012
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0252 0.1043 0.1035
Entamoeba histolytica cysteine protease, putative 0.0051 0.0144 0.0131
Echinococcus granulosus patatin phospholipase domain containing protein 0.0047 0.0127 0.0118
Treponema pallidum cyclic nucleotide binding protein 0.0047 0.0127 0.0114
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0051 0.0144 0.0132
Echinococcus multilocularis microtubule associated protein 2 0.081 0.3538 0.3532
Onchocerca volvulus 0.0032 0.0058 0.0107
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0278 0.1157 0.1147
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0051 0.0144 0.0131
Echinococcus granulosus microtubule associated protein 2 0.081 0.3538 0.3532
Mycobacterium leprae PROBABLE HYDROLASE 0.0363 0.154 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0075 0.0062
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Giardia lamblia Cathepsin B precursor 0.0051 0.0144 0.0131
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0032 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0144 0.0131
Schistosoma mansoni amine GPCR 0.0099 0.036 0.0348
Brugia malayi Cathepsin L-like precursor 0.0278 0.1157 0.1147
Echinococcus granulosus cathepsin l1 0.0186 0.0746 0.0738
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0104 0.0091
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0126 0.0113
Brugia malayi splicing factor 3B subunit 3 0.0032 0.0058 0.0046
Echinococcus granulosus heat shock protein 0.0037 0.0082 0.0073
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0317 0.1334 0.1331
Echinococcus granulosus sodium channel protein 0.0024 0.002 0.0012
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.2251 0.9988 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Entamoeba histolytica CPSF A subunit region protein, putative 0.0032 0.0058 0.0045
Schistosoma mansoni cathepsin s 0.0092 0.0326 0.0313
Echinococcus granulosus voltage dependent calcium channel 0.0024 0.002 0.0012
Schistosoma mansoni histamine h1 receptor 0.0099 0.036 0.0348
Loa Loa (eye worm) hypothetical protein 0.0186 0.0746 0.0743
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0024 0.002 0.0008
Onchocerca volvulus 0.0032 0.0056 0.0103
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0075 0.0062
Trypanosoma cruzi cysteine peptidase, putative 0.0143 0.0555 0.0543
Entamoeba histolytica cysteine protease, putative 0.0051 0.0144 0.0131
Onchocerca volvulus 0.0024 0.002 0.0018
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0051 0.0144 0.0131
Loa Loa (eye worm) hypothetical protein 0.0032 0.0058 0.0053
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0024 0.002 0.0008
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0143 0.0555 0.0543
Echinococcus multilocularis cathepsin L cysteine protease 0.0278 0.1157 0.1149
Echinococcus granulosus voltage dependent calcium channel 0.0024 0.002 0.0012
Schistosoma mansoni ryanodine receptor related 0.0024 0.002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0032 0.0058 0.0053
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0071 0.0233 0.0224
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0099 0.036 0.0348
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0062 0.0049
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0197 0.0794 0.0786
Echinococcus multilocularis neuropeptide Y receptor 0.0099 0.036 0.0351
Echinococcus multilocularis ecdysone induced protein 78C 0.0056 0.0164 0.0155
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0027
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0015 0.0003
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0024 0.0024 0.001
Leishmania major cathepsin L-like protease 0.0333 0.1404 0.1394
Onchocerca volvulus Putative organic anion transporter 0.0032 0.0058 0.0107
Echinococcus multilocularis serotonin receptor 0.0099 0.036 0.0351
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0099 0.036 0.0356
Echinococcus granulosus neuropeptide s receptor 0.0099 0.036 0.0351
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0104 0.0091
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0047 0.0127 0.0114
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0047 0.0127 0.0118
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0317 0.1334 0.1324
Brugia malayi Serotonin receptor 0.0099 0.036 0.0348
Treponema pallidum cyclic nucleotide binding protein 0.0047 0.0127 0.0114
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0144 0.0132
Echinococcus granulosus geminin 0.0394 0.1675 0.1668
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0278 0.1157 0.1147
Echinococcus granulosus cpg binding protein 0.0036 0.0074 0.0065
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0032 0.0058 0.0049
Plasmodium vivax heat shock protein 86, putative 0.0037 0.0082 0.0069
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.036 0.0351
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0051 0.0144 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0144 0.0131
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0143 0.0555 0.0555
Schistosoma mansoni opsin-like receptor 0.0099 0.036 0.0348
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0099 0.0085
Trichomonas vaginalis adenylate cyclase, putative 0.0033 0.0062 0.0049
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0014 0.0001
Leishmania major hypothetical protein, conserved 0.0047 0.0127 0.0114
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0056 0.0164 0.0155
Giardia lamblia Hypothetical protein 0.0051 0.0144 0.0131
Onchocerca volvulus 0.0278 0.1157 0.2684
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.003 0.0048 0.0034
Brugia malayi cathepsin L-like precursor 0.0186 0.0746 0.0735
Echinococcus granulosus serotonin receptor 0.0099 0.036 0.0351
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0278 0.1157 0.1147
Brugia malayi Cathepsin L-like precursor 0.0278 0.1157 0.1147
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0126 0.0126
Brugia malayi Tachykinin-like peptides receptor 99D 0.0099 0.036 0.0348
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0127 0.0114
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0144 0.0132
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0026 0.0032 0.0023
Mycobacterium tuberculosis Conserved protein 0.0042 0.0104 0.0591
Leishmania major regulatory subunit of protein kinase a-like protein 0.0047 0.0127 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0278 0.1157 0.1147
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0056 0.0164 0.0155
Giardia lamblia Cathepsin L precursor 0.0051 0.0144 0.0131
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0104 0.0091
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Echinococcus granulosus tm gpcr rhodopsin 0.0099 0.036 0.0351
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0047 0.0127 0.0788
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Brugia malayi orphan nuclear receptor NR2E1 0.0026 0.0032 0.002
Schistosoma mansoni cathepsin F (C01 family) 0.0278 0.1157 0.1146
Schistosoma mansoni lamin 0.0032 0.0056 0.0044
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0099 0.036 0.0348
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.036 0.0351
Brugia malayi Dopamine receptor protein 1 0.0099 0.036 0.0348
Schistosoma mansoni biogenic amine receptor 0.0099 0.036 0.0348
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0104 0.0091
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0104 0.038 0.0368
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0052 0.0146 0.0146
Leishmania major serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0264 0.1096 0.1085
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0015 0.0002
Echinococcus granulosus ryanodine receptor 44f 0.0024 0.002 0.0012
Onchocerca volvulus 0.0099 0.036 0.0814
Schistosoma mansoni voltage-gated potassium channel 0.0057 0.0168 0.0156
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0047 0.0127 0.0114
Schistosoma mansoni neuropeptide receptor 0.0099 0.036 0.0348
Trypanosoma brucei heat shock protein, putative 0.0037 0.0082 0.0082
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0317 0.1334 1
Leishmania major cathepsin L-like protease 0.0333 0.1404 0.1394
Loa Loa (eye worm) RGS-3 protein 0.0022 0.0015 0.0011
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0144 0.0132
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0015 0.0003
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.002 0.0012
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0024 0.002 0.0008
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0024 0.002 0.0021
Onchocerca volvulus Bile acid receptor homolog 0.0056 0.0164 0.0354
Brugia malayi intermediate filament protein 0.0032 0.0056 0.0044
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0026 0.0032 0.002
Onchocerca volvulus 0.0032 0.0058 0.0107
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0015 0.0007
Schistosoma mansoni organic anion transporter 0.0032 0.0058 0.0046
Treponema pallidum catabolite gene activator (Crp) 0.0047 0.0127 0.0114
Brugia malayi Cathepsin L-like precursor 0.0278 0.1157 0.1147
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0047 0.0127 0.0114
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.004 0.0026
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0099 0.036 0.0351
Trichomonas vaginalis heat shock protein, putative 0.0037 0.0082 0.0069
Echinococcus granulosus potassium voltage gated channel protein 0.0024 0.002 0.0012
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0071 0.0233 0.0228
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0026 0.0032 0.002
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0056 0.0164 0.0155
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0029 0.0046 0.0042
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0024 0.002 0.0012
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0047 0.0127 0.0114
Loa Loa (eye worm) voltage-dependent calcium channel 0.0024 0.002 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.083 0.0819
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0029 0.0046 0.0034
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0032 0.0023
Trichomonas vaginalis adenylate cyclase type, putative 0.0033 0.0062 0.0049
Brugia malayi Egg laying defective protein 4 0.0047 0.0127 0.0115
Echinococcus multilocularis splicing factor 3b subunit 3 0.0032 0.0058 0.0049
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0264 0.1096 0.1085
Trichomonas vaginalis heat shock protein, putative 0.003 0.0048 0.0034
Trichomonas vaginalis set domain proteins, putative 0.0279 0.1162 0.1151
Echinococcus granulosus potassium voltage gated channel protein 0.0024 0.002 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0087 0.0073
Trypanosoma brucei cysteine peptidase C (CPC) 0.0051 0.0144 0.0144
Mycobacterium ulcerans hypothetical protein 0.0042 0.0104 0.0091
Trichomonas vaginalis adenylate cyclase type, putative 0.0033 0.0062 0.0049
Schistosoma mansoni neuropeptide receptor 0.0099 0.036 0.0348
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0047 0.0127 0.0268
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0317 0.1334 0.1324
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0015 0.0003
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0197 0.0794 0.0786
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0033 0.0062 0.0049
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.1348 0.5947 0.5943
Entamoeba histolytica cysteine protease, putative 0.0143 0.0555 0.0542
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0359 0.1521 0.1514
Brugia malayi Papain family cysteine protease containing protein 0.0143 0.0555 0.0543
Brugia malayi Glutamate receptor 1 precursor 0.0026 0.003 0.0017
Trypanosoma cruzi Flagellar Member 6 0.0047 0.0127 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0056 0.0164 0.0151
Trypanosoma brucei DNA polymerase IV, putative 0.0047 0.0126 0.0126
Echinococcus multilocularis cpg binding protein 0.0036 0.0074 0.0065
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0104 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0087 0.0073
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Schistosoma mansoni retinoic acid receptor RXR 0.0056 0.0164 0.0151
Brugia malayi Papain family cysteine protease containing protein 0.0278 0.1157 0.1147
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0024 0.002 0.0018
Leishmania major cysteine peptidase A (CPA) 0.0278 0.1157 0.1147
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.131 0.1308
Loa Loa (eye worm) hypothetical protein 0.0186 0.0746 0.0743
Giardia lamblia Cysteine protease 0.0051 0.0144 0.0131
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0029 0.0046 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0278 0.1157 0.1147
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0317 0.1334 0.1324
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0051 0.0144 0.0131
Onchocerca volvulus 0.0026 0.0032 0.0046
Schistosoma mansoni zinc finger protein 0.0026 0.0032 0.002
Echinococcus multilocularis cathepsin b 0.0051 0.0144 0.0135
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0026 0.0032 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.036 0.0351
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0104 0.0095
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.2251 0.9988 1
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Echinococcus multilocularis expressed conserved protein 0.0047 0.0127 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0317 0.1334 0.1324
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0144 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0051 0.0144 0.0131
Plasmodium falciparum serine repeat antigen 2 0.0051 0.0144 0.0131
Brugia malayi angiogenesis inhibito 0.0167 0.0662 0.0651
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0024 0.002 0.0012
Onchocerca volvulus Protein ultraspiracle homolog 0.0056 0.0164 0.0354
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0335 0.1416 0.1406
Trypanosoma cruzi cysteine peptidase, putative 0.0333 0.1404 0.1394
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0024 0.002 0.0007
Trichomonas vaginalis adenylate cyclase, putative 0.0033 0.0062 0.0049
Echinococcus multilocularis adam 17 protease 0.0223 0.0912 0.0904
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0033 0.0062 0.0049
Schistosoma mansoni heat shock protein 0.0037 0.0082 0.0069
Trichomonas vaginalis esterase, putative 0.0042 0.0104 0.0091
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0015 0.0003
Brugia malayi G-protein coupled receptor 0.0099 0.036 0.0348
Echinococcus granulosus hyperpolarization activated cyclic 0.0071 0.0233 0.0224
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.0233 0.022
Schistosoma mansoni amine GPCR 0.0099 0.036 0.0348
Brugia malayi hypothetical protein 0.0026 0.0032 0.002
Trypanosoma brucei cytochrome P450, putative 0.0028 0.0041 0.0041
Leishmania major cathepsin L-like protease 0.0278 0.1157 0.1147
Echinococcus granulosus allatostatin A receptor 0.0099 0.036 0.0351
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0317 0.1334 0.1324
Echinococcus granulosus transient receptor potential cation channel 0.0024 0.002 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0099 0.036 0.0351
Echinococcus granulosus hyperpolarization activated cyclic 0.0071 0.0233 0.0224
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Echinococcus multilocularis cathepsin b 0.0051 0.0144 0.0135
Brugia malayi putative neuropeptide receptor NPR1 0.0099 0.036 0.0348
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0099 0.036 0.0348
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0051 0.0144 0.0131
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0075 0.0075
Plasmodium vivax splicing factor 3B subunit 3, putative 0.0032 0.0058 0.0045
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.002 0.0012
Loa Loa (eye worm) matrixin family protein 0.0985 0.4322 0.4324
Mycobacterium tuberculosis Possible penicillin-binding protein 0.027 0.1122 0.7264
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0317 0.1334 0.1322
Schistosoma mansoni ap endonuclease 0.0022 0.0014 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0099 0.0085
Brugia malayi Nuclear hormone receptor-like 1 0.0056 0.0164 0.0151
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0053 0.0039
Loa Loa (eye worm) hypothetical protein 0.0104 0.038 0.0376
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0032 0.002
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.2254 1 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0058 0.0053
Brugia malayi Endoplasmin precursor 0.0037 0.0082 0.0069
Loa Loa (eye worm) hypothetical protein 0.0047 0.0127 0.0122
Onchocerca volvulus 0.0034 0.0066 0.0124
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0047 0.0127 0.0114
Loa Loa (eye worm) glutamate receptor 2 0.0026 0.003 0.0025
Mycobacterium ulcerans regulatory protein 0.0047 0.0127 0.0114
Echinococcus multilocularis follistatin 0.0022 0.0013 0.0004
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0047 0.0127 0.0114
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0071 0.0233 0.0224
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0099 0.036 0.0356
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0144 0.0131
Loa Loa (eye worm) calcium channel 0.0024 0.002 0.0016
Loa Loa (eye worm) steroid hormone receptor 0.0056 0.0164 0.0159
Echinococcus granulosus short transient receptor potential channel 6 0.0024 0.002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0581 0.2513 0.2513
Trichomonas vaginalis DNA polymerase eta, putative 0.0047 0.0126 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0039 0.0026
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0099 0.036 0.0351
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0024 0.002 0.0008
Echinococcus granulosus cathepsin L cysteine protease 0.0143 0.0555 0.0546
Loa Loa (eye worm) hypothetical protein 0.0312 0.1309 0.1307
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0022 0.0015 0.0003
Leishmania major hypothetical protein, conserved 0.0047 0.0127 0.0114
Schistosoma mansoni transient receptor potential channel 0.0024 0.002 0.0008
Loa Loa (eye worm) hypothetical protein 0.026 0.1079 0.1076
Trichomonas vaginalis spliceosomal protein sap, putative 0.0032 0.0058 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0015 0.0002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0046 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0051 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0144 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0056 0.0164 0.0151
Echinococcus granulosus peptide allatostatin:somatostatin 0.0099 0.036 0.0351
Echinococcus multilocularis nmda type glutamate receptor 0.0034 0.0066 0.0057
Mycobacterium ulcerans heat shock protein 90 0.003 0.0048 0.0034
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0099 0.036 0.0348
Trypanosoma brucei cAMP response protein 1, putative 0.0047 0.0127 0.0127
Echinococcus granulosus g protein coupled receptor 0.0099 0.036 0.0351
Echinococcus multilocularis expressed protein 0.0438 0.1874 0.1867
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0047 0.0127 0.0114
Echinococcus granulosus nmda type glutamate receptor 0.0034 0.0066 0.0057
Giardia lamblia Cathepsin B precursor 0.0051 0.0144 0.0131
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.0032 0.0046
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0024 0.002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0051 0.0144 0.0139
Brugia malayi neuropeptide F receptor 0.0099 0.036 0.0348
Schistosoma mansoni intermediate filament proteins 0.0032 0.0056 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0126 0.0126
Echinococcus granulosus potassium voltage gated channel protein 0.0024 0.002 0.0012
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Onchocerca volvulus 0.0278 0.1157 0.2684
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0051 0.0144 0.0131
Schistosoma mansoni voltage-gated potassium channel 0.0104 0.038 0.0368
Echinococcus granulosus calcium activated potassium channel 0.0024 0.002 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0144 0.0131
Schistosoma mansoni organic anion transporter 0.0032 0.0058 0.0046
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0029 0.0046 0.0034
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0047 0.0127 0.0118
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0099 0.036 0.0351
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0056 0.0164 0.0155
Trypanosoma cruzi cysteine peptidase, putative 0.0278 0.1157 0.1147
Loa Loa (eye worm) endoplasmin 0.0037 0.0082 0.0077
Brugia malayi Disintegrin family protein 0.0169 0.0669 0.0658
Onchocerca volvulus 0.0042 0.0104 0.0214
Plasmodium falciparum serine repeat antigen 5 0.0051 0.0144 0.0131
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0033 0.0062 0.0049
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0024 0.002 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.036 0.0351
Echinococcus granulosus dro:myosuppressin receptor 0.0099 0.036 0.0351
Leishmania major cathepsin L-like protease 0.0278 0.1157 0.1147
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0144 0.0131
Echinococcus multilocularis somatostatin receptor 0.0099 0.036 0.0351
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0144 0.0131
Plasmodium vivax SET domain protein, putative 0.0036 0.0075 0.0061
Onchocerca volvulus 0.0036 0.0075 0.0146
Schistosoma mansoni cathepsin F (C01 family) 0.0186 0.0746 0.0735
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Echinococcus granulosus tm gpcr rhodopsin 0.1116 0.4907 0.4903
Entamoeba histolytica cysteine protease, putative 0.0143 0.0555 0.0542
Entamoeba histolytica cysteine protease, putative 0.0143 0.0555 0.0542
Echinococcus granulosus transient receptor potential cation channel 0.0024 0.002 0.0012
Echinococcus multilocularis lamin 0.0032 0.0056 0.0048
Brugia malayi steroid hormone receptor 0.0056 0.0164 0.0151
Brugia malayi ORL1-like opioid receptor 0.0099 0.036 0.0348
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0027
Entamoeba histolytica cysteine protease, putative 0.0143 0.0555 0.0542
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.036 0.0348
Brugia malayi nuclear hormone receptor 0.0056 0.0164 0.0151
Schistosoma mansoni hypothetical protein 0.0047 0.0127 0.0114
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0027
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0047 0.0127 0.0114
Loa Loa (eye worm) matrix metalloproteinase 0.0351 0.1485 0.1482
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0024 0.002 0.0008
Onchocerca volvulus 0.0032 0.0058 0.0107
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0024 0.002 0.0008
Echinococcus granulosus hypothetical protein 0.0099 0.036 0.0351
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0099 0.036 0.0348
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0052 0.0146 0.0133
Onchocerca volvulus Cathepsin L homolog 0.0278 0.1157 0.2684
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0104 0.038 0.0372
Entamoeba histolytica heat shock protein 90, putative 0.0037 0.0082 0.0068
Schistosoma mansoni voltage-gated potassium channel 0.0392 0.1669 0.1658
Loa Loa (eye worm) hypothetical protein 0.0029 0.0046 0.0042
Brugia malayi PXA domain containing protein 0.0022 0.0015 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.0144 0.0139
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Echinococcus granulosus G protein coupled receptor 139 0.0099 0.036 0.0351
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0024 0.002 0.0018
Trichomonas vaginalis fk506-binding protein, putative 0.0317 0.1334 0.1324
Onchocerca volvulus 0.0318 0.1337 0.3105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0087 0.0073
Echinococcus granulosus cathepsin l cysteine peptidase 0.0278 0.1157 0.1149
Onchocerca volvulus 0.0099 0.036 0.0814
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0047 0.0127 0.0865
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.2251 0.9988 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Entamoeba histolytica cysteine proteinase 2 0.0143 0.0555 0.0542
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0015 0.0007
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0047 0.0127 0.0865
Echinococcus granulosus cGMP dependent protein kinase 0.0047 0.0127 0.0118
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0099 0.036 0.0351
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0008
Toxoplasma gondii target of rapamycin (TOR), putative 0.0038 0.0087 0.056
Echinococcus granulosus FK506 binding protein 2 0.0365 0.1549 0.1541
Onchocerca volvulus 0.0278 0.1157 0.2684
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0047 0.0127 0.0114
Loa Loa (eye worm) hypothetical protein 0.0051 0.0144 0.0139
Echinococcus multilocularis orexin receptor type 2 0.0099 0.036 0.0351
Brugia malayi hypothetical protein 0.0032 0.0058 0.0046
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0144 0.0139
Echinococcus multilocularis ryanodine receptor 44f 0.0024 0.002 0.0012
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.2251 0.9988 0.9997
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0024 0.002 0.0012
Trypanosoma brucei cAMP binding protein, putative 0.0047 0.0127 0.0127
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0021 0.0011 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0056 0.0164 0.0159
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0024 0.002 0.0012
Loa Loa (eye worm) AGC/PKG protein kinase 0.0047 0.0127 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0056 0.0164 0.0151
Brugia malayi Matrixin family protein 0.0351 0.1485 0.1475
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0071 0.0233 0.0228
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0024 0.0024 0.001
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0148 0.0576 0.0567
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Entamoeba histolytica cysteine protease, putative 0.0143 0.0555 0.0542
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Trypanosoma cruzi serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0264 0.1096 0.1085
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0022 0.0015 0.0007
Echinococcus multilocularis cathepsin L 0.0051 0.0144 0.0135
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0024 0.002 0.0012
Echinococcus granulosus Solute carrier organic anion transporter family 0.0032 0.0058 0.0049
Brugia malayi photoreceptor-specific nuclear receptor 0.0056 0.0164 0.0151
Brugia malayi ADAM-TS Spacer 1 family protein 0.0319 0.134 0.133
Echinococcus multilocularis hyperpolarization activated cyclic 0.0071 0.0233 0.0224
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0317 0.1334 0.1324
Brugia malayi tailless protein 0.0026 0.0032 0.002
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0015 0.0003
Loa Loa (eye worm) hypothetical protein 0.0036 0.0075 0.007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0027
Brugia malayi beta-lactamase family protein 0.0042 0.0104 0.0091
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0047 0.0127 0.0118
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0127 0.0114
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Echinococcus multilocularis dnaJ subfamily B 0.048 0.2062 0.2055
Plasmodium vivax unspecified product 0.0092 0.0326 0.0313
Echinococcus multilocularis nuclear receptor nhr 48 0.0026 0.0032 0.0023
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0099 0.036 0.0356
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0033 0.0062 0.0049
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0126 0.0113
Plasmodium falciparum serine repeat antigen 4 0.0051 0.0144 0.0131
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0024 0.002 0.0008
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0033 0.0062 0.0049
Loa Loa (eye worm) hypothetical protein 0.0042 0.0104 0.0099
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0047 0.0127 0.0114
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0031 0.0051 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0143 0.0555 0.0543
Echinococcus granulosus transient receptor potential gamma protein 0.0024 0.002 0.0012
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0365 0.1549 0.1539
Brugia malayi heat shock protein 90 0.0037 0.0082 0.0069
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0047 0.0127 0.0114
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0014 0.0005
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0099 0.036 0.0348
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0082 0.0069
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0051 0.0144 0.0139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.036 0.0348
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0056 0.0164 0.0151
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0056 0.0164 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0062 0.0049
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0051 0.0144 0.0131
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0099 0.036 0.0348
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0071 0.0233 0.0228
Loa Loa (eye worm) melatonin receptor type 1A 0.0099 0.036 0.0356
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0056 0.0164 0.0151
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0051 0.0144 0.0131
Brugia malayi hypothetical protein 0.0099 0.036 0.0348
Trypanosoma brucei heat shock protein, putative 0.0037 0.0082 0.0082
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0144 0.0132
Toxoplasma gondii cathepsin B 0.0051 0.0144 0.0995
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0144 0.0132
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0033 0.0062 0.0049
Echinococcus multilocularis g protein coupled receptor 0.0099 0.036 0.0351
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0024 0.0023 0.0063
Giardia lamblia Cathepsin L precursor 0.0051 0.0144 0.0131
Brugia malayi hypothetical protein 0.0099 0.036 0.0348
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0056 0.0164 0.0159
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Entamoeba histolytica cysteine protease, putative 0.0051 0.0144 0.0131
Toxoplasma gondii splicing factor 3b, subunit 3, putative 0.0032 0.0058 0.0344
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0104 0.0091
Brugia malayi hypothetical protein 0.0026 0.0032 0.002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0027
Trypanosoma brucei unspecified product 0.004 0.0092 0.0092
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0024 0.002 0.0012
Echinococcus granulosus splicing factor 3b subunit 3 0.0032 0.0058 0.0049
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.2251 0.9988 1
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0071 0.0233 0.0224
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0034 0.0066 0.0057
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0051 0.0144 0.0131
Echinococcus granulosus potassium voltage gated channel protein 0.0024 0.002 0.0012
Mycobacterium tuberculosis Conserved hypothetical protein 0.0047 0.0127 0.0743
Brugia malayi nuclear receptor RXR 0.0029 0.0046 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0015 0.0003
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0144 0.0139
Echinococcus granulosus 7TM GPCR rhodopsin 0.0099 0.036 0.0351
Onchocerca volvulus 0.0351 0.1485 0.3452
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0278 0.1157 0.1147
Schistosoma mansoni hypothetical protein 0.0033 0.0062 0.005
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0099 0.036 0.0348
Echinococcus granulosus transient receptor potential cation channel 0.0024 0.002 0.0012
Schistosoma mansoni opsin-like receptor 0.0099 0.036 0.0348
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0143 0.0555 0.0543
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Echinococcus granulosus follistatin 0.0022 0.0013 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.036 0.0348
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0104 0.0091
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.2251 0.9988 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0144 0.0132
Brugia malayi hypothetical protein 0.0022 0.0015 0.0003
Loa Loa (eye worm) hypothetical protein 0.0092 0.0326 0.0321
Entamoeba histolytica cysteine protease, putative 0.0143 0.0555 0.0542
Brugia malayi voltage-dependent calcium channel 0.0024 0.002 0.0008
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Plasmodium vivax endoplasmin, putative 0.0037 0.0082 0.0069
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0051 0.0144 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0015 0.0002
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0365 0.1549 0.1539
Schistosoma mansoni glutamate receptor NMDA 0.0031 0.0051 0.0039
Echinococcus granulosus voltage gated potassium channel 0.0104 0.038 0.0372
Onchocerca volvulus Matrix metalloproteinase homolog 0.0714 0.311 0.7263
Loa Loa (eye worm) hypothetical protein 0.0092 0.0326 0.0321
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0027
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.003 0.0048 0.0225
Onchocerca volvulus 0.0278 0.1157 0.2684
Onchocerca volvulus 0.0099 0.036 0.0814
Toxoplasma gondii cathepsin CPC1 0.0051 0.0144 0.0995
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0024 0.002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Schistosoma mansoni alpha-1 adrenergic receptor 0.0099 0.036 0.0348
Echinococcus granulosus neuropeptides capa receptor 0.0099 0.036 0.0351
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0144 0.0132
Trichomonas vaginalis adenylate cyclase, putative 0.0033 0.0062 0.0049
Schistosoma mansoni immunophilin 0.1937 0.8581 0.8579
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0052 0.0146 0.0132
Trichomonas vaginalis adenylate cyclase, putative 0.0033 0.0062 0.0049
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0317 0.1334 0.1324
Plasmodium falciparum cysteine proteinase falcipain 1 0.0143 0.0555 0.0543
Mycobacterium leprae Possible transporter protein 0.0033 0.0062 0.0097
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.083 0.0819
Loa Loa (eye worm) hypothetical protein 0.0056 0.0164 0.0159
Brugia malayi Cathepsin L-like precursor 0.0278 0.1157 0.1147
Onchocerca volvulus Cathepsin F homolog 0.0278 0.1157 0.2684
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0026 0.0032 0.0023
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0015 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0056 0.0164 0.0159
Loa Loa (eye worm) hypothetical protein 0.0319 0.134 0.1338
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0278 0.1157 0.1147
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0264 0.1096 0.1083
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0144 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0278 0.1157 0.1147
Toxoplasma gondii protein phosphatase 2B catalytic subunit, calcineurin family phosphatse superfamily protein 0.0264 0.1096 0.8196
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0099 0.036 0.0348
Toxoplasma gondii heat shock protein HSP90 0.0037 0.0082 0.0524
Trypanosoma cruzi major cysteine proteinase, putative 0.0106 0.0391 0.0379
Schistosoma mansoni glutamate receptor AMPA 0.0026 0.003 0.0017
Echinococcus multilocularis dro:myosuppressin receptor 0.0099 0.036 0.0351
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.002 0.0008
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0046 0.0034
Trypanosoma cruzi cruzipain precursor, putative 0.0333 0.1404 0.1394
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0024 0.002 0.0008
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0024 0.002 0.0008
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0015 0.0003
Echinococcus multilocularis short transient receptor potential channel 6 0.0024 0.002 0.0012
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0047 0.0127 0.0743
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0359 0.1521 0.1514
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0359 0.1521 0.1519
Leishmania major hypothetical protein, conserved 0.0024 0.002 0.0007
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0264 0.1096 0.1088
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0126 0.0126
Entamoeba histolytica cysteine protease, putative 0.0051 0.0144 0.0131
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0051 0.0144 0.0132
Trichomonas vaginalis adenylate cyclase, putative 0.0033 0.0062 0.0049
Loa Loa (eye worm) hypothetical protein 0.0032 0.0058 0.0053
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Giardia lamblia Cathepsin L precursor 0.0051 0.0144 0.0131
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0024 0.002 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0333 0.1404 0.1406
Brugia malayi sulfakinin receptor protein 0.0099 0.036 0.0348
Echinococcus multilocularis g-protein coupled receptor 0.0099 0.036 0.0351
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.2254 1 1
Trypanosoma cruzi cysteine proteinase, putative 0.0143 0.0555 0.0543
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0047 0.0127 0.0114
Echinococcus granulosus g protein coupled receptor 0.0099 0.036 0.0351
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0146 0.0133
Mycobacterium ulcerans hypothetical protein 0.0047 0.0127 0.0114
Schistosoma mansoni ap endonuclease 0.0022 0.0014 0.0001
Brugia malayi follicle stimulating hormone receptor 0.0099 0.036 0.0348
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0047 0.0127 0.0114
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0026 0.003 0.0021
Leishmania major hypothetical protein, unknown function 0.0024 0.002 0.0007
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0052 0.0146 0.0133
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0033 0.0062 0.0049
Trypanosoma brucei heat shock protein 90, putative 0.0037 0.0082 0.0082
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0051 0.0144 0.0131
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.2251 0.9988 1
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0033 0.0062 0.0049
Echinococcus granulosus orexin receptor type 2 0.0099 0.036 0.0351
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.0206 0.1465
Onchocerca volvulus Neuropeptide F receptor homolog 0.0099 0.036 0.0814
Echinococcus multilocularis potassium voltage gated channel protein 0.0024 0.002 0.0012
Loa Loa (eye worm) ion channel NompC 0.0024 0.002 0.0016
Schistosoma mansoni neuropeptide receptor 0.0099 0.036 0.0348
Mycobacterium tuberculosis Conserved hypothetical protein 0.0047 0.0127 0.0743
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0056 0.0164 0.0159
Onchocerca volvulus 0.0099 0.036 0.0814
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0052 0.0146 0.0132
Loa Loa (eye worm) hypothetical protein 0.0047 0.0127 0.0122
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0075 0.047
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0052 0.0146 0.0133
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0056 0.0164 0.0151
Toxoplasma gondii hypothetical protein 0.0024 0.002 0.0059
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0024 0.002 0.0008
Echinococcus multilocularis voltage gated potassium channel 0.0024 0.002 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0126 0.0126
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0104 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0144 0.0131
Schistosoma mansoni hypothetical protein 0.0373 0.1584 0.1574
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0042 0.0104 0.0099
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0144 0.0131
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0015 0.0003
Echinococcus granulosus dna polymerase kappa 0.0047 0.0126 0.0117
Loa Loa (eye worm) G-protein coupled receptor 0.0099 0.036 0.0356
Echinococcus multilocularis sodium channel protein 0.0024 0.002 0.0012
Brugia malayi Matrixin family protein 0.0351 0.1485 0.1475
Schistosoma mansoni transient receptor potential channel 0.0024 0.002 0.0008
Trichomonas vaginalis adenylate cyclase, putative 0.0033 0.0062 0.0049
Trichomonas vaginalis adenylate cyclase type, putative 0.0033 0.0062 0.0049
Entamoeba histolytica cysteine protease, putative 0.0278 0.1157 0.1145
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0008
Brugia malayi G protein-coupled receptor 0.0099 0.036 0.0348
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0278 0.1157 0.1147
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0056 0.0164 0.0159
Echinococcus granulosus neuropeptides capa receptor 0.0099 0.036 0.0351
Echinococcus granulosus biogenic amine 5HT receptor 0.0099 0.036 0.0351
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0333 0.1404 0.1406
Schistosoma mansoni thyroid hormone receptor 0.0203 0.0825 0.0813
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.036 0.0348
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0015 0.0002
Trypanosoma brucei heat shock protein, putative 0.0037 0.0082 0.0082
Echinococcus multilocularis transient receptor potential gamma protein 0.0024 0.002 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0099 0.0085
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0047 0.0127 0.0127
Brugia malayi metalloprotease 0.0059 0.018 0.0168
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0032 0.0023
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0032 0.002
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0024 0.002 0.0008
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0024 0.002 0.0008
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Schistosoma mansoni transient receptor potential channel 0.0024 0.002 0.0008
Trichomonas vaginalis adenylate cyclase type III, putative 0.0033 0.0062 0.0049
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0104 0.038 0.0372
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0333 0.1404 0.1406
Giardia lamblia Encystation-specific protease 0.0051 0.0144 0.0131
Loa Loa (eye worm) hypothetical protein 0.0042 0.0104 0.0099
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.002 0.0008
Schistosoma mansoni biogenic amine receptor 0.0099 0.036 0.0348
Echinococcus multilocularis heat shock protein 90 0.0037 0.0082 0.0073
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0051 0.0144 0.0132
Schistosoma mansoni heat shock protein 0.0037 0.0082 0.0069
Echinococcus multilocularis neuropeptides capa receptor 0.0099 0.036 0.0351
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0317 0.1334 0.1324
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0062 0.0049
Brugia malayi Dopamine receptor protein 2 0.0099 0.036 0.0348
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0126 0.0126
Echinococcus multilocularis fmrfamide receptor 0.0099 0.036 0.0351
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0278 0.1157 0.1147
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0278 0.1157 0.1147
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.0144 0.0131
Loa Loa (eye worm) matrixin family protein 0.0714 0.311 0.311
Schistosoma mansoni protein phosphatase-2b 0.0264 0.1096 0.1084
Trypanosoma cruzi protein kinase A regulatory subunit 0.0047 0.0127 0.0114
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.0233 0.022
Echinococcus granulosus TRP transient receptor potential channel 0.0024 0.002 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0051 0.0144 0.0131
Brugia malayi cathepsin Z-like cysteine proteinase 0.0051 0.0144 0.0132
Mycobacterium leprae Probable lipase LipE 0.0042 0.0104 0.0375
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.2251 0.9988 1
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0033 0.0062 0.0049
Brugia malayi nuclear hormone receptor family member odr-7 0.0026 0.0032 0.002
Trichomonas vaginalis heat shock protein, putative 0.003 0.0048 0.0034
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0363 0.154 1
Echinococcus multilocularis Regulator of G protein signaling 20 0.0022 0.0015 0.0007
Plasmodium vivax vivapain-1 0.0143 0.0555 0.0543
Brugia malayi Matrixin family protein 0.0351 0.1485 0.1475
Schistosoma mansoni endoplasmin 0.0037 0.0082 0.0069
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0024 0.002 0.0008
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0317 0.1334 0.8649
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0047 0.0127 0.0115
Echinococcus granulosus voltage gated potassium channel 0.0024 0.002 0.0012
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0092 0.0326 0.0314
Brugia malayi hypothetical protein 0.0032 0.0058 0.0046
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.131 0.13
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0027
Trypanosoma brucei heat shock protein, putative 0.0037 0.0082 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0317 0.1334 0.1324
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0028 0.0041 0.0028
Giardia lamblia Heat shock protein HSP 90-alpha 0.0037 0.0082 0.0069
Plasmodium falciparum serine repeat antigen 1 0.0051 0.0144 0.0131
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0024 0.002 0.0012
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0015 0.0003
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0047 0.0127 0.0122
Schistosoma mansoni hypothetical protein 0.0099 0.036 0.0348
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.2251 0.9988 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0041 0.0036
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0278 0.1157 0.1147
Schistosoma mansoni cathepsin B (C01 family) 0.0051 0.0144 0.0132
Trypanosoma cruzi cAMP response protein 1, putative 0.0047 0.0127 0.0114
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0032 0.0023
Schistosoma mansoni neuropeptide F-like receptor 0.0099 0.036 0.0348
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0047 0.0127 0.0743
Onchocerca volvulus Matrilysin homolog 0.0351 0.1485 0.3452
Brugia malayi GnHR receptor homolog 0.0099 0.036 0.0348
Leishmania major cytochrome p450-like protein 0.0028 0.0041 0.0028
Onchocerca volvulus Putative organic anion transporter 0.0032 0.0058 0.0107
Trichomonas vaginalis heat shock protein, putative 0.003 0.0048 0.0034
Echinococcus granulosus rhodopsin orphan GPCR 0.0099 0.036 0.0351
Trypanosoma brucei heat shock protein, putative 0.0037 0.0082 0.0082
Schistosoma mansoni glutamate receptor kainate 0.0026 0.003 0.0017
Echinococcus multilocularis shaker cognate 0.0024 0.002 0.0012
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0024 0.002 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0333 0.1404 0.1406
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0144 0.0132
Brugia malayi Steroid receptor seven-up type 2 0.0056 0.0164 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0056 0.0164 0.0151
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0099 0.036 0.0351
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.131 0.13
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.003 0.0048 0.026
Mycobacterium ulcerans hypothetical protein 0.0047 0.0127 0.0114
Echinococcus granulosus disintegrin and metalloproteinase 0.0169 0.0669 0.0661
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0099 0.036 0.0351
Echinococcus multilocularis fmrfamide receptor 0.0099 0.036 0.0351
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0024 0.002 0.0012
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0051 0.0144 0.0131
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0317 0.1334 0.1324
Trypanosoma cruzi target of rapamycin kinase 3 0.0041 0.0099 0.0086
Schistosoma mansoni cathepsin S (C01 family) 0.0051 0.0144 0.0132
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0612 0.2652 0.2643
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0062 0.0049
Loa Loa (eye worm) cathepsin B 0.0051 0.0144 0.0139
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.032 0.1346 0.1338
Plasmodium vivax vivapain-3 0.0143 0.0555 0.0543
Brugia malayi nuclear receptor RXR 0.0026 0.0032 0.002
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0051 0.0144 0.0131
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0047 0.0127 0.0114
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0032 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0746 0.0735
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0047 0.0127 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0056 0.0164 0.0151
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0333 0.1404 0.1406
Loa Loa (eye worm) hypothetical protein 0.0032 0.0058 0.0053
Brugia malayi ion channel NompC 0.0024 0.002 0.0008
Echinococcus multilocularis sex peptide receptor 0.0099 0.036 0.0351
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0317 0.1334 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0075 0.0066
Schistosoma mansoni glutamate receptor kainate 0.0026 0.003 0.0017
Brugia malayi hypothetical protein 0.0029 0.0046 0.0034
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0278 0.1157 0.1149
Loa Loa (eye worm) hypothetical protein 0.0103 0.0377 0.0373
Entamoeba histolytica cysteine proteinase, putative 0.0143 0.0555 0.0542
Schistosoma mansoni dihydroceramide desaturase 0.0169 0.0669 0.0658
Giardia lamblia Cysteine protease 0.0051 0.0144 0.0131
Loa Loa (eye worm) disintegrin family protein 0.0074 0.0247 0.0242
Giardia lamblia Cathepsin L-like protease 0.0051 0.0144 0.0131
Toxoplasma gondii heat shock protein 90, putative 0.0037 0.0082 0.0524
Echinococcus multilocularis geminin 0.0394 0.1675 0.1668
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0047 0.0127 0.0115
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0317 0.1334 0.1324
Brugia malayi CXXC zinc finger family protein 0.0034 0.0066 0.0053
Mycobacterium ulcerans beta-lactamase 0.0042 0.0104 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0051 0.0144 0.0131
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0039 0.0026
Onchocerca volvulus Putative organic anion transporter 0.0032 0.0058 0.0107
Brugia malayi sodium-independent organic anion transporter family protein 0.0032 0.0058 0.0046
Echinococcus granulosus rhodopsin orphan GPCR 0.0099 0.036 0.0351
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.131 0.13
Entamoeba histolytica cysteine proteinase, putative 0.0278 0.1157 0.1145
Loa Loa (eye worm) CXXC zinc finger family protein 0.0034 0.0066 0.0061
Schistosoma mansoni RAR-like nuclear receptor 0.0056 0.0164 0.0151
Brugia malayi nuclear receptor NHR-88 0.0056 0.0164 0.0151
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0024 0.002 0.0012
Schistosoma mansoni two-pore calcium channel 0.0024 0.002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0056 0.0164 0.0159
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0033 0.0062 0.0049
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0031 0.0051 0.0043
Schistosoma mansoni thyroid hormone receptor 0.0203 0.0825 0.0813
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.007 0.0056
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0024 0.002 0.0012
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.025 0.1033 0.1025
Echinococcus multilocularis allatostatin A receptor 0.0099 0.036 0.0351
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0104 0.0591
Echinococcus granulosus expressed protein 0.0438 0.1874 0.1867
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Entamoeba histolytica cysteine protease, putative 0.0143 0.0555 0.0542
Loa Loa (eye worm) hypothetical protein 0.0029 0.0046 0.0042
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0104 0.0091
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0047 0.0127 0.0114
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0026 0.0032 0.0023
Leishmania major cathepsin L-like protease 0.0333 0.1404 0.1394
Plasmodium vivax vivapain-2 0.0278 0.1157 0.1147
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0047 0.0127 0.0743
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0062 0.0049
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0099 0.036 0.0814
Echinococcus granulosus two pore calcium channel protein 2 0.0024 0.002 0.0012
Plasmodium vivax vivapain-2 0.0278 0.1157 0.1147
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0015 0.0003
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.1937 0.8581 0.858
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0041 0.0099 0.0085
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0144 0.0132
Echinococcus multilocularis g protein coupled receptor 0.0099 0.036 0.0351
Echinococcus granulosus sodium leak channel non selective protein 0.0024 0.002 0.0012
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0264 0.1096 0.1083
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0031 0.0051 0.0043
Schistosoma mansoni adenoreceptor 0.0099 0.036 0.0348
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.029 0.1213 0.1202
Trypanosoma brucei protein phosphatase 2B, putative 0.0264 0.1096 0.1097
Schistosoma mansoni nuclear receptor 0.0026 0.0032 0.002
Echinococcus multilocularis calcium activated potassium channel 0.0024 0.002 0.0012
Entamoeba histolytica hypothetical protein 0.0022 0.0015 0.0002
Echinococcus multilocularis G protein coupled receptor 139 0.0099 0.036 0.0351
Entamoeba histolytica cysteine proteinase 1, putative 0.0143 0.0555 0.0542
Schistosoma mansoni glutamate receptor kainate 0.0026 0.003 0.0017
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0052 0.0146 0.0137
Echinococcus multilocularis voltage gated potassium channel 0.0104 0.038 0.0372
Echinococcus granulosus transient receptor potential cation channel 0.0024 0.002 0.0012
Loa Loa (eye worm) G-protein coupled receptor 0.0099 0.036 0.0356
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0062 0.0049
Echinococcus granulosus potassium large conductance calcium activated 0.0024 0.002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0163 0.0642 0.0638
Brugia malayi cathepsin L precursor 0.0051 0.0144 0.0132
Onchocerca volvulus 0.0099 0.036 0.0814
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0015 0.0007
Echinococcus granulosus 7tm_1 domain containing protein 0.0099 0.036 0.0351
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0024 0.002 0.0008
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0051 0.0144 0.0131
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.036 0.0348
Schistosoma mansoni hypothetical protein 0.0394 0.1675 0.1665
Trypanosoma cruzi MFS transporter, putative 0.0032 0.0058 0.0045
Brugia malayi hypothetical protein 0.0022 0.0015 0.0003
Trypanosoma cruzi cAMP response protein 1 0.0047 0.0127 0.0114
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.002 0.0008
Schistosoma mansoni neuropeptide F-like receptor 0.0099 0.036 0.0348
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0033 0.0062 0.0049
Onchocerca volvulus Papilin homolog 0.0069 0.0224 0.0495
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0051 0.0144 0.0131
Loa Loa (eye worm) hypothetical protein 0.0051 0.0144 0.0139
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0104 0.0095
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0264 0.1096 0.1083
Brugia malayi Cyclic-nucleotide gated cation channel 0.0071 0.0233 0.0221
Leishmania major protein kinase, putative 0.0047 0.0127 0.0114
Entamoeba histolytica cysteine protease, putative 0.0143 0.0555 0.0542
Echinococcus granulosus cGMP dependent protein kinase 1 0.0047 0.0127 0.0118
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0047 0.0127 0.0118
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0333 0.1404 0.1406
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0104 0.0091
Loa Loa (eye worm) hypothetical protein 0.0278 0.1157 0.1154
Onchocerca volvulus 0.0278 0.1157 0.2684
Trypanosoma cruzi Heat shock protein 83, putative 0.0037 0.0082 0.0069
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0056 0.0164 0.0354
Echinococcus granulosus glutamate receptor 2 0.0031 0.0051 0.0043
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0024 0.002 0.0008
Loa Loa (eye worm) voltage-gated potassium channel 0.0024 0.002 0.0016
Giardia lamblia Hypothetical protein 0.0317 0.1334 0.1324
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0051 0.0144 0.0131
Trypanosoma cruzi cysteine proteinase, putative 0.0143 0.0555 0.0543
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0317 0.1334 0.1331
Entamoeba histolytica cysteine protease, putative 0.0143 0.0555 0.0542
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0335 0.1416 0.1406
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0011
Loa Loa (eye worm) phosphatidylinositol 3 0.0052 0.0146 0.0141
Echinococcus granulosus lamin dm0 0.0032 0.0056 0.0048
Echinococcus granulosus neuropeptide Y receptor 0.0099 0.036 0.0351
Loa Loa (eye worm) hypothetical protein 0.0317 0.1334 0.1331
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0264 0.1096 0.1088
Brugia malayi Serine/threonine protein phosphatase 2B catalytic subunit 2 0.0264 0.1096 0.1085
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0278 0.1157 0.1147
Brugia malayi hypothetical protein 0.0099 0.036 0.0348
Echinococcus granulosus biogenic amine 5HT receptor 0.0099 0.036 0.0351
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0022 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Trichomonas vaginalis immunophilin, putative 0.2251 0.9988 1
Schistosoma mansoni voltage-dependent calcium channel 0.0024 0.002 0.0008
Schistosoma mansoni hypothetical protein 0.0148 0.0576 0.0564
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0071 0.0233 0.022
Onchocerca volvulus 0.0042 0.0104 0.0214
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1116 0.4907 0.4903
Plasmodium falciparum endoplasmin, putative 0.0023 0.0017 0.0004
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.002 0.0008
Trichomonas vaginalis adenylate cyclase, putative 0.0033 0.0062 0.0049
Giardia lamblia Cathepsin B precursor 0.0051 0.0144 0.0131
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.083 0.0819
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0024 0.002 0.0008
Schistosoma mansoni biogenic amine (5HT) receptor 0.0099 0.036 0.0348
Loa Loa (eye worm) hypothetical protein 0.0042 0.0104 0.0099
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0071 0.0233 0.022
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0066 0.0057
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.2251 0.9988 1
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0047 0.0127 0.0114
Schistosoma mansoni cpg binding protein 0.0036 0.0074 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0112 0.0099
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0015 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0087 0.0073
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0033 0.0062 0.0049
Echinococcus multilocularis regulator of G protein signaling 0.0022 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0011
Mycobacterium ulcerans hypothetical protein 0.0047 0.0127 0.0114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0087 0.0073
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0056 0.0164 0.0155
Echinococcus granulosus transient receptor potential cation channel 0.0024 0.002 0.0012
Treponema pallidum heat shock protein 90 0.003 0.0048 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0062 0.0049
Loa Loa (eye worm) agrin synaptic family protein 0.0022 0.0013 0.0008
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0317 0.1334 0.1324
Echinococcus multilocularis heat shock protein 0.0037 0.0082 0.0073
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Loa Loa (eye worm) angiogenesis inhibito 0.0064 0.02 0.0195
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0024 0.002 0.0012
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0033 0.0062 0.0049
Giardia lamblia Cathepsin B precursor 0.0051 0.0144 0.0131
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0075 0.0062
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.002 0.0008
Echinococcus multilocularis glutamate receptor 2 0.0026 0.003 0.0021
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Schistosoma mansoni ATP-binding cassette transporter 0.0026 0.003 0.0017
Plasmodium falciparum serine repeat antigen 9 0.0051 0.0144 0.0131
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0241 0.0993 0.0983
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0024 0.002 0.0008
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0024 0.002 0.0008
Loa Loa (eye worm) TYRA-2 protein 0.0099 0.036 0.0356
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0317 0.1334 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0056 0.0164 0.0151
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0056 0.0164 0.0155
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0104 0.0591
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.2251 0.9988 1
Onchocerca volvulus 0.0099 0.036 0.0814
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.0233 0.022
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0014 0.0005
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0047 0.0127 0.0865
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0041 0.0028
Brugia malayi putative neuropeptide receptor 0.0099 0.036 0.0348
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0032 0.002
Plasmodium falciparum serine repeat antigen 6 0.0051 0.0144 0.0131
Echinococcus multilocularis voltage dependent calcium channel 0.0024 0.002 0.0012
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0104 0.0091
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.2251 0.9988 0.9988
Echinococcus multilocularis conserved hypothetical protein 0.0024 0.002 0.0012
Toxoplasma gondii transporter, cation channel family protein 0.0024 0.002 0.0059
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.036 0.0348
Echinococcus granulosus cathepsin L 0.0051 0.0144 0.0135
Echinococcus granulosus tachykinin peptides receptor 99D 0.0099 0.036 0.0351
Echinococcus granulosus thyroid hormone receptor alpha 0.0026 0.0032 0.0023
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Leishmania major cyclic nucleotide-binding protein-like protein 0.0047 0.0127 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0186 0.0746 0.0735
Echinococcus granulosus neuropeptide FF receptor 2 0.0099 0.036 0.0351
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0024 0.002 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.036 0.0348
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0056 0.0164 0.0151
Giardia lamblia Cathepsin L precursor 0.0051 0.0144 0.0131
Onchocerca volvulus 0.0373 0.1584 0.3685
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0099 0.036 0.0348
Schistosoma mansoni nuclear receptor nhr-48 0.0026 0.0032 0.002
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0144 0.0132
Loa Loa (eye worm) hypothetical protein 0.0056 0.0164 0.0159
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0031 0.0051 0.0043
Loa Loa (eye worm) hypothetical protein 0.0187 0.0751 0.0747
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0033 0.0062 0.0049
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.025 0.1033 0.1021
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0024 0.002 0.0012
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Loa Loa (eye worm) neuropeptide F receptor 0.0099 0.036 0.0356
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0071 0.0233 0.022
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0317 0.1334 0.1324
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0062 0.0049
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0056 0.0164 0.0155
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.2251 0.9988 1
Treponema pallidum catabolite gene activator 0.005 0.0139 0.0126
Echinococcus granulosus cathepsin L 0.0143 0.0555 0.0546
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0047 0.0127 0.0114
Echinococcus multilocularis cathepsin L cysteine protease 0.0278 0.1157 0.1149
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Trypanosoma cruzi cysteine peptidase, putative 0.0333 0.1404 0.1394
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0033 0.0062 0.0062
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0317 0.1334 0.1324
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.1937 0.8581 0.858
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0027
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.025 0.1033 0.1021
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0029 0.0046 0.0037
Brugia malayi nuclear hormone receptor 0.0026 0.0032 0.002
Schistosoma mansoni biogenic amine receptor 0.0099 0.036 0.0348
Schistosoma mansoni hypothetical protein 0.0099 0.036 0.0348
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0317 0.1334 0.8618
Echinococcus multilocularis cathepsin L 0.0143 0.0555 0.0546
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0365 0.1549 0.1539
Leishmania major cathepsin L-like protease 0.0278 0.1157 0.1147
Trichomonas vaginalis adenylate cyclase, putative 0.0033 0.0062 0.0049
Loa Loa (eye worm) hypothetical protein 0.0051 0.0144 0.0139
Schistosoma mansoni hypothetical protein 0.0024 0.002 0.0008
Trypanosoma brucei Heat shock protein 83, putative 0.0037 0.0082 0.0082
Brugia malayi conserved hypotetical protein 0.0026 0.0032 0.002
Brugia malayi RE15519p 0.0099 0.036 0.0348
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0047 0.0127 0.0118
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0015 0.0007
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0032 0.0058 0.0049
Onchocerca volvulus 0.0186 0.0746 0.1721
Echinococcus multilocularis neuropeptides capa receptor 0.0099 0.036 0.0351
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0104 0.0091
Loa Loa (eye worm) hypothetical protein 0.0056 0.0164 0.0159
Trypanosoma cruzi cAMP binding protein, putative 0.0047 0.0127 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0278 0.1157 0.1147
Brugia malayi G protein-coupled receptor F59B2.13 0.0099 0.036 0.0348
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0092 0.0092
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0056 0.0164 0.0151
Schistosoma mansoni opsin-like receptor 0.0099 0.036 0.0348
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0052 0.0146 0.0133
Trypanosoma brucei heat shock protein, putative 0.0037 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0051 0.0144 0.0139
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0278 0.1157 0.1154
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0099 0.036 0.0351
Echinococcus granulosus cathepsin l1 0.0278 0.1157 0.1149
Schistosoma mansoni nuclear receptor 0.0026 0.0032 0.002
Mycobacterium ulcerans DNA polymerase IV 0.0047 0.0126 0.0113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0056 0.0164 0.0159
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0032 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0062 0.0049
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0264 0.1096 0.1088
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Onchocerca volvulus 0.0032 0.0056 0.0103
Schistosoma mansoni amine GPCR 0.0099 0.036 0.0348
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0104 0.0591
Loa Loa (eye worm) voltage-gated calcium channel 0.0024 0.002 0.0016
Brugia malayi Cytochrome P450 family protein 0.0028 0.0041 0.0029
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0099 0.036 0.0351
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.036 0.0348
Trypanosoma brucei DNA polymerase IV, putative 0.0047 0.0126 0.0126
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0022 0.0013 0.0008
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0264 0.1096 0.1085
Schistosoma mansoni cathepsin C 0.0051 0.0144 0.0132
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0099 0.036 0.0351
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.131 0.13
Onchocerca volvulus 0.0279 0.1162 0.2694
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0056 0.0164 0.0151
Schistosoma mansoni hypothetical protein 0.0099 0.036 0.0348
Trichomonas vaginalis adenylate cyclase type III, putative 0.0033 0.0062 0.0049
Brugia malayi prostaglandin transporter 0.0032 0.0058 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0144 0.0131
Brugia malayi cathepsin F-like cysteine proteinase 0.0092 0.0326 0.0314
Echinococcus granulosus FTZ F1 alpha 0.0056 0.0164 0.0155
Loa Loa (eye worm) hypothetical protein 0.0032 0.0058 0.0053
Brugia malayi Glutamate receptor 2 precursor 0.0026 0.003 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0333 0.1404 0.1406
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0143 0.0555 0.0543
Onchocerca volvulus 0.0026 0.0032 0.0046
Brugia malayi regulator of G-protein signaling egl-10 0.0022 0.0015 0.0003
Echinococcus granulosus fmrfamide receptor 0.0099 0.036 0.0351
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0056 0.0164 0.0155
Leishmania major serine/threonine protein phosphatase, putative 0.0264 0.1096 0.1085
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.003 0.0048 0.0039
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0105 0.0386 0.0374
Brugia malayi Pre-SET motif family protein 0.0036 0.0075 0.0062
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.1348 0.5947 0.5943
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0033 0.0062 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0024 0.002 0.0012
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0024 0.0024 0.001
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0015 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.002 0.0008
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0099 0.036 0.0351
Schistosoma mansoni glutamate receptor AMPA 0.0026 0.003 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.036 0.0351
Onchocerca volvulus 0.0032 0.0058 0.0107
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0099 0.036 0.0351
Schistosoma mansoni voltage-gated cation channel 0.0024 0.002 0.0008
Trypanosoma cruzi heat shock protein 90, putative 0.0037 0.0082 0.0069
Onchocerca volvulus 0.0099 0.036 0.0814
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0033 0.0062 0.0049
Mycobacterium ulcerans transmembrane transport protein 0.0047 0.0127 0.0114
Echinococcus multilocularis fk506 binding protein 0.2251 0.9988 0.9988
Brugia malayi hypothetical protein 0.0099 0.036 0.0348
Trypanosoma brucei heat shock protein, putative 0.0037 0.0082 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0126 0.0126
Schistosoma mansoni 60S ribosomal protein L21 0.0057 0.0168 0.0156
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0099 0.036 0.0348
Schistosoma mansoni steroid hormone receptor ad4bp 0.0056 0.0164 0.0151
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.0223 0.0912 0.0901
Echinococcus granulosus ecdysone induced protein 78C 0.0056 0.0164 0.0155
Entamoeba histolytica cysteine protease, putative 0.0143 0.0555 0.0542
Trichomonas vaginalis endoplasmin, putative 0.0023 0.0017 0.0004
Echinococcus granulosus dnaJ subfamily B 0.048 0.2062 0.2055
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0056 0.0164 0.0151
Giardia lamblia Cathepsin B precursor 0.0051 0.0144 0.0131
Plasmodium falciparum serine repeat antigen 8 0.0051 0.0144 0.0131
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0015 0.0011
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0099 0.036 0.0351
Brugia malayi cation channel family protein 0.0024 0.002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Echinococcus multilocularis hyperpolarization activated cyclic 0.0071 0.0233 0.0224
Echinococcus multilocularis heat shock protein 90 0.003 0.0048 0.0039
Toxoplasma gondii hypothetical protein 0.0024 0.002 0.0059
Entamoeba histolytica cysteine protease, putative 0.0143 0.0555 0.0542
Trypanosoma cruzi heat shock protein 90, putative 0.003 0.0048 0.0035
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0024 0.002 0.0008
Brugia malayi Serotonin receptor 0.0099 0.036 0.0348
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0041 0.0099 0.0099
Schistosoma mansoni voltage-gated potassium channel 0.0392 0.1669 0.1658
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.2251 0.9988 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0104 0.0099
Brugia malayi ecdysteroid receptor 0.0056 0.0164 0.0151
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0027
Onchocerca volvulus 0.0278 0.1157 0.2684
Loa Loa (eye worm) hypothetical protein 0.0056 0.0164 0.0159
Toxoplasma gondii transporter, cation channel family protein 0.0024 0.002 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0099 0.0085
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0014 0.0009
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.002 0.0008
Echinococcus granulosus glutamate NMDA receptor subunit 0.0026 0.003 0.0021
Brugia malayi Papain family cysteine protease containing protein 0.0143 0.0555 0.0543
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0047 0.0127 0.0118
Echinococcus granulosus g-protein coupled receptor 0.0099 0.036 0.0351
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0099 0.036 0.0351
Brugia malayi hypothetical protein 0.0099 0.036 0.0348
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Echinococcus granulosus rhodopsin orphan GPCR 0.0099 0.036 0.0351
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.2251 0.9988 1
Brugia malayi hypothetical protein 0.029 0.1213 0.1203
Trichomonas vaginalis heat shock protein, putative 0.0023 0.0017 0.0004
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Schistosoma mansoni transient receptor potential channel 4 0.0024 0.002 0.0008
Echinococcus granulosus alpha 1A adrenergic receptor 0.0099 0.036 0.0351
Brugia malayi olfactory channel protein osm-9 0.0024 0.002 0.0008
Brugia malayi PXA domain containing protein 0.0022 0.0015 0.0003
Trichomonas vaginalis fk506 binding protein, putative 0.0317 0.1334 0.1324
Giardia lamblia Cathepsin B precursor 0.0051 0.0144 0.0131
Brugia malayi sodium-independent organic anion transporter family protein 0.0032 0.0058 0.0046
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0099 0.036 0.0351
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0071 0.0233 0.0224
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0073 0.024 0.0228
Brugia malayi cathepsin L-like cysteine proteinase 0.0051 0.0144 0.0132
Giardia lamblia Heat shock protein HSP 90-alpha 0.003 0.0048 0.0034
Toxoplasma gondii ABC1 family protein 0.0042 0.0104 0.069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0146 0.0133
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0104 0.0091
Echinococcus granulosus sex peptide receptor 0.0099 0.036 0.0351
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0075 0.0066
Brugia malayi Matrixin family protein 0.0985 0.4322 0.4318
Loa Loa (eye worm) cysteine protease 0.0278 0.1157 0.1154
Trypanosoma brucei heat shock protein, putative 0.0037 0.0082 0.0082
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0024 0.0024 0.0066
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0104 0.0375
Echinococcus granulosus neuropeptide Y receptor 0.0099 0.036 0.0351
Giardia lamblia Cathepsin L precursor 0.0051 0.0144 0.0131
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0317 0.1334 0.1336
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0052 0.0146 0.0133
Trypanosoma cruzi cysteine protease, putative 0.0143 0.0555 0.0543
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0126 0.0113
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0197 0.0794 0.0783
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0024 0.002 0.0012
Trypanosoma brucei protein kinase A regulatory subunit 0.0047 0.0127 0.0127
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0365 0.1549 0.1546
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Echinococcus multilocularis agrin 0.0022 0.0013 0.0004
Mycobacterium tuberculosis Conserved protein 0.0042 0.0104 0.0591
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0143 0.0555 0.0543
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0022 0.0015 0.0002
Leishmania major hypothetical protein, conserved 0.0047 0.0127 0.0114
Giardia lamblia DINP protein human, muc B family 0.0024 0.0023 0.001
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0071 0.0233 0.0224
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0051 0.0144 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0278 0.1157 0.1147
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0099 0.036 0.0356
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0056 0.0164 0.0159
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0056 0.0164 0.0155
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0047 0.0127 0.0127
Entamoeba histolytica hypothetical protein 0.0022 0.0015 0.0002
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0047 0.0127 0.0114
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0317 0.1334 0.1324
Echinococcus multilocularis potassium voltage gated channel protein 0.0024 0.002 0.0012
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0099 0.036 0.0348
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0033 0.0062 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0278 0.1157 0.1147
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.2251 0.9988 0.9988
Loa Loa (eye worm) hypothetical protein 0.0029 0.0046 0.0042
Giardia lamblia Cathepsin B precursor 0.0051 0.0144 0.0131
Schistosoma mansoni neuropeptide f receptor 76f 0.0099 0.036 0.0348
Toxoplasma gondii transporter, cation channel family protein 0.0024 0.002 0.0059
Trichomonas vaginalis adenylate cyclase, putative 0.0033 0.0062 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0099 0.036 0.0348
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0104 0.0591
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0333 0.1404 0.1406
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0144 0.0131
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0071 0.0233 0.022
Echinococcus granulosus neuropeptide receptor 0.0099 0.036 0.0351
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0051 0.0144 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.004 0.0026
Onchocerca volvulus 0.0317 0.1334 0.3098
Onchocerca volvulus 0.0047 0.0127 0.0268
Onchocerca volvulus Matrilysin homolog 0.0975 0.4277 1
Brugia malayi hypothetical protein 0.0099 0.036 0.0348
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0047 0.0127 0.0118
Echinococcus granulosus adam 0.029 0.1213 0.1205
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0056 0.0164 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0053 0.0039
Onchocerca volvulus 0.0099 0.036 0.0814
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0033 0.0062 0.0049
Loa Loa (eye worm) hypothetical protein 0.0056 0.0164 0.0159
Brugia malayi Cathepsin L-like cysteine proteinase 0.0186 0.0746 0.0735
Entamoeba histolytica cysteine proteinase, putative 0.0143 0.0555 0.0542
Brugia malayi nuclear hormone receptor family member nhr-6 0.0026 0.0032 0.002
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0033 0.0062 0.0049
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.002 0.0008
Onchocerca volvulus 0.0099 0.036 0.0814
Echinococcus granulosus cathepsin b 0.0051 0.0144 0.0135
Brugia malayi Cathepsin L-like precursor 0.0092 0.0326 0.0314
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0015 0.0003
Brugia malayi larval opioid receptor 0.0099 0.036 0.0348
Plasmodium falciparum serine/threonine protein phosphatase 2B catalytic subunit A 0.0264 0.1096 0.1085
Giardia lamblia Cathepsin L precursor 0.0051 0.0144 0.0131
Echinococcus multilocularis potassium large conductance calcium activated 0.0024 0.002 0.0012
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0024 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0027
Plasmodium vivax serine-repeat antigen (SERA) 0.0051 0.0144 0.0131
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0278 0.1157 0.1149
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0015 0.0002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0014 0.0014
Brugia malayi beta-lactamase 0.0042 0.0104 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0087 0.0073
Echinococcus granulosus nuclear receptor nhr 48 0.0026 0.0032 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0056 0.0164 0.0151
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0264 0.1096 0.1088
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Loa Loa (eye worm) glutamate receptor 1 0.0026 0.003 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0144 0.0131
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0056 0.0164 0.0159
Loa Loa (eye worm) hypothetical protein 0.0351 0.1485 0.1482
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.002 0.0008
Loa Loa (eye worm) reprolysin 0.025 0.1033 0.103
Schistosoma mansoni neuropeptide receptor 0.0099 0.036 0.0348
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0333 0.1404 0.1406
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Loa Loa (eye worm) nuclear hormone receptor 0.0026 0.0032 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0278 0.1157 0.1147
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0024 0.002 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.036 0.0351
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0144 0.0131
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0278 0.1157 0.1147
Onchocerca volvulus 0.0051 0.0144 0.0308
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.002 0.0008
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0099 0.036 0.0351
Brugia malayi sodium-independent organic anion transporter family protein 0.0032 0.0058 0.0046
Toxoplasma gondii transporter, major facilitator family protein 0.0032 0.0058 0.0344
Plasmodium falciparum cysteine proteinase falcipain 3 0.0278 0.1157 0.1147
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0099 0.036 0.0348
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0031 0.0051 0.0043
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0015 0.0007
Echinococcus granulosus neuropeptide receptor A26 0.0099 0.036 0.0351
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.088 0.0868
Mycobacterium ulcerans hydrolase 0.0363 0.154 0.1531
Plasmodium falciparum heat shock protein 90 0.0037 0.0082 0.0069
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0317 0.1334 1
Echinococcus multilocularis sodium leak channel non selective protein 0.0024 0.002 0.0012
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.0056 0.0052
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0024 0.002 0.0012
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.002 0.0012
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0052 0.0146 0.0133
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0015 0.0003
Echinococcus multilocularis short transient receptor potential channel 6 0.0024 0.002 0.0012
Brugia malayi Dopamine receptor 0.0099 0.036 0.0348
Brugia malayi cation channel family protein 0.0024 0.002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Leishmania major fk506-binding protein 1-like protein 0.2251 0.9988 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0051 0.0144 0.0132
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0024 0.002 0.0008
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0051 0.0144 0.0131
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0052 0.0146 0.0146
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0051 0.0144 0.0131
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0024 0.002 0.0008
Loa Loa (eye worm) PXA domain-containing protein 0.0022 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0042 0.0104 0.0099
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.083 0.0819
Echinococcus multilocularis two pore calcium channel protein 1 0.0024 0.002 0.0012
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0071 0.0233 0.0224
Toxoplasma gondii cathepsin CPL 0.0278 0.1157 0.8663
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0245 0.1011 0.1008
Onchocerca volvulus 0.0032 0.0058 0.0107
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0024 0.002 0.0012
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Trypanosoma cruzi cysteine peptidase, putative 0.0092 0.0326 0.0313
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0278 0.1157 0.1147
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.0056 0.0044
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0015 0.0003
Brugia malayi hypothetical protein 0.0099 0.036 0.0348
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0278 0.1157 0.1154
Onchocerca volvulus 0.0042 0.0104 0.0214
Brugia malayi Cathepsin L-like precursor 0.0186 0.0746 0.0735
Onchocerca volvulus 0.0032 0.0058 0.0107
Echinococcus multilocularis FTZ F1 alpha 0.0056 0.0164 0.0155
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Echinococcus granulosus hypothetical protein 0.0024 0.002 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0127 0.0114
Echinococcus granulosus intermediate filament protein 0.0032 0.0056 0.0048
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0056 0.0164 0.0151
Entamoeba histolytica cysteine proteinase, putative 0.0143 0.0555 0.0542
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0024 0.002 0.0021
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0047 0.0127 0.0115
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0365 0.1549 0.1537
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Brugia malayi hypothetical protein 0.0099 0.036 0.0348
Echinococcus multilocularis thyroid hormone receptor alpha 0.0203 0.0825 0.0817
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0047 0.0127 0.0865
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0317 0.1334 0.1324
Schistosoma mansoni ADAMTS14 peptidase (M12 family) 0.0059 0.018 0.0168
Schistosoma mansoni z-protein (S1r protein) 0.0022 0.0015 0.0003
Entamoeba histolytica heat shock protein 90, putative 0.0037 0.0082 0.0068
Brugia malayi cathepsin B-like cysteine proteinase 0.0051 0.0144 0.0132
Entamoeba histolytica cysteine proteinase, putative 0.0278 0.1157 0.1145
Schistosoma mansoni immunophilin 0.2254 1 1
Echinococcus granulosus transient receptor potential cation channel 0.0024 0.002 0.0012
Echinococcus multilocularis neuropeptide s receptor 0.0099 0.036 0.0351
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0082 0.0069
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0056 0.0164 0.0151
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0026 0.0032 0.0027
Schistosoma mansoni growth hormone secretagogue receptor 0.0099 0.036 0.0348
Brugia malayi Transient-receptor-potential like protein 0.0024 0.002 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0143 0.0555 0.0555
Trypanosoma brucei Flagellar Member 6 0.0047 0.0127 0.0127
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0359 0.1521 0.1512
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0062 0.0049
Loa Loa (eye worm) hypothetical protein 0.0042 0.0104 0.0099
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0051 0.0144 0.0132
Brugia malayi hypothetical protein 0.0029 0.0046 0.0034
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0075 0.0062
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0051 0.0144 0.0131
Leishmania major protein kinase A regulatory subunit, putative 0.0047 0.0127 0.0114
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0011
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0143 0.0555 0.0543
Echinococcus granulosus potassium voltage gated channel protein 0.0024 0.002 0.0012
Plasmodium vivax unspecified product 0.0051 0.0144 0.0131
Trypanosoma cruzi cysteine peptidase, putative 0.0333 0.1404 0.1394
Onchocerca volvulus 0.0099 0.036 0.0814
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0317 0.1334 0.1336
Trichomonas vaginalis adenylate cyclase, putative 0.0033 0.0062 0.0049
Onchocerca volvulus 0.0099 0.036 0.0814
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.083 0.1917
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.002 0.0008
Brugia malayi neuropeptide F receptor 0.0099 0.036 0.0348
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0278 0.1157 0.1147
Schistosoma mansoni immunophilin 0.2254 1 1
Loa Loa (eye worm) neuropeptide F receptor 0.0099 0.036 0.0356
Onchocerca volvulus 0.0278 0.1157 0.2684
Echinococcus multilocularis disintegrin and metalloproteinase 0.0169 0.0669 0.0661
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0047 0.0127 0.0114
Onchocerca volvulus Cathepsin L homolog 0.0278 0.1157 0.2684
Trypanosoma cruzi DNA polymerase kappa, putative 0.0047 0.0126 0.0113
Onchocerca volvulus 0.0056 0.0164 0.0354
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0099 0.036 0.0351
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0056 0.0164 0.0151
Loa Loa (eye worm) hypothetical protein 0.0186 0.0746 0.0743
Schistosoma mansoni nuclear hormone receptor 0.0056 0.0164 0.0151
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.083 0.0819
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0317 0.1334 0.1326
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0099 0.036 0.0356
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0071 0.0233 0.022
Loa Loa (eye worm) hypothetical protein 0.1935 0.8572 0.8581
Schistosoma mansoni amine GPCR 0.0099 0.036 0.0348
Loa Loa (eye worm) beta-lactamase 0.0042 0.0104 0.0099
Mycobacterium ulcerans hypothetical protein 0.0047 0.0127 0.0114
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0082 0.0069
Loa Loa (eye worm) FKBP5 protein 0.2251 0.9988 1
Echinococcus granulosus g protein coupled receptor 0.0099 0.036 0.0351
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0015 0.0003
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0099 0.036 0.0351
Leishmania major cathepsin L-like protease 0.0278 0.1157 0.1147
Schistosoma mansoni fk506 binding protein 0.0317 0.1334 0.1323
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0092 0.0326 0.0321
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Mycobacterium ulcerans hypothetical protein 0.0365 0.1549 0.1539
Brugia malayi hypothetical protein 0.0099 0.036 0.0348
Loa Loa (eye worm) hypothetical protein 0.0032 0.0058 0.0053
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0047 0.0127 0.0114
Echinococcus granulosus cGMP dependent protein kinase 1 0.0047 0.0127 0.0118
Schistosoma mansoni hypothetical protein 0.0099 0.036 0.0348
Brugia malayi Hemopexin family protein 0.0373 0.1584 0.1575
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0317 0.1334 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0056 0.0164 0.0151
Echinococcus granulosus Regulator of G protein signaling 20 0.0022 0.0015 0.0007
Echinococcus granulosus short transient receptor potential channel 6 0.0024 0.002 0.0012
Entamoeba histolytica cysteine protease, putative 0.0051 0.0144 0.0131
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.0032 0.0046
Brugia malayi hypothetical protein 0.0099 0.036 0.0348
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0278 0.1157 0.1147
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0024 0.0023 0.001
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0099 0.036 0.0351
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0041 0.0028
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0278 0.1157 0.1147
Echinococcus multilocularis potassium voltage gated channel protein 0.0024 0.002 0.0012
Echinococcus granulosus voltage gated hydrogen channel 1 0.0024 0.002 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0099 0.036 0.0351
Echinococcus granulosus tm gpcr rhodopsin 0.0099 0.036 0.0351
Echinococcus multilocularis adam 0.029 0.1213 0.1205
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0033 0.0062 0.0049
Echinococcus granulosus heat shock protein 90 0.0037 0.0082 0.0073
Leishmania major protein kinase, putative 0.0047 0.0127 0.0114
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0032 0.0023
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0033 0.0062 0.0049
Onchocerca volvulus 0.0047 0.0127 0.0268
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.083 0.0819
Leishmania major cathepsin L-like protease 0.0278 0.1157 0.1147
Echinococcus multilocularis musashi 0.0032 0.0056 0.0048
Brugia malayi Cathepsin L-like precursor 0.0278 0.1157 0.1147
Schistosoma mansoni coup transcription factor 0.0056 0.0164 0.0151
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.2251 0.9988 1
Schistosoma mansoni hypothetical protein 0.048 0.2062 0.2052
Schistosoma mansoni cathepsin F (C01 family) 0.0278 0.1157 0.1146
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.2252 0.9991 1
Echinococcus multilocularis 0.0365 0.1549 0.1541
Brugia malayi fibroinase precursor 0.0051 0.0144 0.0132
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0024 0.002 0.0008
Echinococcus granulosus neuropeptide receptor 0.0099 0.036 0.0351
Echinococcus granulosus endoplasmin 0.003 0.0048 0.0039
Trypanosoma brucei heat shock protein 90, putative 0.0037 0.0082 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.131 0.13
Leishmania major peptidylprolyl isomerase-like protein 0.2251 0.9988 1
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0047 0.0127 0.0743
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0099 0.036 0.0348
Brugia malayi cathepsin Z-like cysteine proteinase 0.0051 0.0144 0.0132
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0144 0.0132
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0363 0.154 0.1531
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0056 0.0164 0.0155
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.131 0.13
Toxoplasma gondii exonuclease III APE 0.0022 0.0014 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0015 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.131 0.13
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0024 0.002 0.0012
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.002 0.0012
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0046 0.0034
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0144 0.0308
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0333 0.1404 0.1406
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0027
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0099 0.036 0.0348
Brugia malayi Pre-SET motif family protein 0.0245 0.1011 0.1
Echinococcus granulosus somatostatin receptor 0.0099 0.036 0.0351
Echinococcus multilocularis glutamate receptor 2 0.0031 0.0051 0.0043
Brugia malayi Reprolysin 0.0155 0.061 0.0599
Loa Loa (eye worm) voltage-gated potassium channel 0.0024 0.002 0.0016
Leishmania major hypothetical protein, conserved 0.0042 0.0104 0.0091
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0075 0.0066
Loa Loa (eye worm) hypothetical protein 0.0363 0.154 0.1538
Schistosoma mansoni cpg binding protein 0.0036 0.0074 0.0062
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0071 0.0233 0.0224
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.01 0.0362 0.035
Echinococcus multilocularis transfer RNA-Gly 0.0024 0.002 0.0012
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0015 0.0007
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0317 0.1334 1
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0024 0.002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0036 0.0075 0.007
Echinococcus multilocularis neuropeptide FF receptor 2 0.0099 0.036 0.0351
Giardia lamblia Cathepsin B precursor 0.0051 0.0144 0.0131
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0047 0.0127 0.0865
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.004 0.0026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0027
Brugia malayi Melatonin receptor type 1A 0.0099 0.036 0.0348
Entamoeba histolytica cysteine proteinase, putative 0.0186 0.0746 0.0734
Loa Loa (eye worm) hypothetical protein 0.0351 0.1485 0.1482
Echinococcus multilocularis cysteine protease 0.0278 0.1157 0.1149
Schistosoma mansoni glutamate receptor NMDA 0.0026 0.003 0.0017
Echinococcus multilocularis neuropeptide Y receptor 0.0099 0.036 0.0351
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0278 0.1157 0.1147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0146 0.0133
Loa Loa (eye worm) hypothetical protein 0.0051 0.0144 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0099 0.0085
Brugia malayi Matrixin family protein 0.0351 0.1485 0.1475
Loa Loa (eye worm) ryanodine receptor 0.0024 0.002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0056 0.0164 0.0159
Schistosoma mansoni protein phosphatase-2b 0.0264 0.1096 0.1084
Echinococcus granulosus cathepsin b 0.0051 0.0144 0.0135
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0365 0.1549 0.1551
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0144 0.0132
Schistosoma mansoni microtubule-associated protein tau 0.081 0.3538 0.3529
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0264 0.1096 0.1083
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0031 0.0051 0.0043
Plasmodium vivax serine/threonine protein phosphatase 2B catalytic subunit A, putative 0.0264 0.1096 0.1085
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0099 0.036 0.0351
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0024 0.002 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0099 0.036 0.0351
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0051 0.0038
Echinococcus multilocularis neuropeptide receptor A26 0.0099 0.036 0.0351
Entamoeba histolytica hypothetical protein 0.0022 0.0015 0.0002
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0148 0.0576 0.0567
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0047 0.0127 0.0118
Entamoeba histolytica cysteine proteinase, putative 0.0143 0.0555 0.0542
Brugia malayi ADAMTS-like protease 0.0167 0.0662 0.0651
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0032 0.0058 0.0053
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0047 0.0127 0.0114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0087 0.0073
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Brugia malayi N-terminal motif family protein 0.0047 0.0127 0.0115
Schistosoma mansoni biogenic amine (5HT) receptor 0.0099 0.036 0.0348
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0015 0.0007
Loa Loa (eye worm) heat shock protein 90 0.0037 0.0082 0.0077
Leishmania major heat shock protein 83-1 0.0037 0.0082 0.0069
Trypanosoma brucei hypothetical protein, conserved 0.0317 0.1334 0.1336
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.004 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0047 0.0126 0.0126
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0104 0.0591
Echinococcus multilocularis potassium voltage gated channel protein 0.0024 0.002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0059 0.018 0.0175
Loa Loa (eye worm) hypothetical protein 0.0022 0.0015 0.0011
Plasmodium vivax unspecified product 0.0143 0.0555 0.0543
Loa Loa (eye worm) metalloprotease 0.0059 0.018 0.0175
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0278 0.1157 0.1147
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0033 0.0062 0.0049
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0024 0.002 0.0012
Toxoplasma gondii cathepsin CPC2 0.0051 0.0144 0.0995
Echinococcus multilocularis g protein coupled receptor 0.0099 0.036 0.0351
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0099 0.036 0.0348
Echinococcus multilocularis voltage dependent calcium channel 0.0024 0.002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Brugia malayi Cathepsin L-like precursor 0.0278 0.1157 0.1147
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0031 0.0051 0.0043
Onchocerca volvulus 0.0099 0.036 0.0814
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.002 0.0008
Entamoeba histolytica cysteine protease, putative 0.0051 0.0144 0.0131
Giardia lamblia Cathepsin L-like protease 0.0051 0.0144 0.0131
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0032 0.0058 0.0049
Loa Loa (eye worm) hypothetical protein 0.0099 0.036 0.0356
Loa Loa (eye worm) hypothetical protein 0.0029 0.0046 0.0042
Brugia malayi Cytochrome P450 family protein 0.0028 0.0041 0.0029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0278 0.1157 0.1147
Loa Loa (eye worm) nuclear receptor NHR-67 0.0026 0.0032 0.0027
Loa Loa (eye worm) DR-78 0.0026 0.0032 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.088 0.0868
Loa Loa (eye worm) hypothetical protein 0.0032 0.0058 0.0053
Echinococcus granulosus single minded 2 0.0033 0.0062 0.0054
Loa Loa (eye worm) hypothetical protein 0.0612 0.2652 0.2652
Echinococcus granulosus heat shock protein 90 0.003 0.0048 0.0039
Onchocerca volvulus 0.0099 0.036 0.0814
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0047 0.0127 0.0118
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0015 0.0007
Trichomonas vaginalis guanylate cyclase, putative 0.0033 0.0062 0.0049
Onchocerca volvulus 0.0099 0.036 0.0814
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0022 0.0015 0.0007
Schistosoma mansoni voltage-gated ion channel 0.0024 0.002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0264 0.1096 0.1093
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0023 0.0023
Brugia malayi polk-prov protein 0.0036 0.0075 0.0062
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0015 0.0011
Schistosoma mansoni endoplasmin 0.0037 0.0082 0.0069
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0041 0.0036
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0252 0.1043 0.1035
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0041 0.0036
Schistosoma mansoni calcium-activated potassium channel 0.0024 0.002 0.0008
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0047 0.0127 0.0865
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0024 0.002 0.0059
Echinococcus multilocularis endoplasmin 0.003 0.0048 0.0039
Schistosoma mansoni voltage-gated potassium channel 0.0104 0.038 0.0368
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0317 0.1334 1
Onchocerca volvulus 0.0099 0.036 0.0814
Onchocerca volvulus 0.0099 0.036 0.0814
Mycobacterium tuberculosis Conserved protein 0.0042 0.0104 0.0591
Schistosoma mansoni amine GPCR 0.0099 0.036 0.0348
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.2251 0.9988 1

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 8.5 nM The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloproteinase-8) ChEMBL. 9457244
Ki (binding) = 8.5 nM The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloproteinase-8) ChEMBL. 9457244
Ki (binding) = 19 nM Binding affinity towards 72 kDa gelatinase (Matrix metalloproteinase-2) ChEMBL. 9457244
Ki (binding) = 19 nM Binding affinity towards 72 kDa gelatinase (Matrix metalloproteinase-2) ChEMBL. 9457244
Ki (binding) = 22 nM The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9) ChEMBL. 9457244
Ki (binding) = 22 nM The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9) ChEMBL. 9457244
Ki (binding) = 280 nM The compound was tested for its binding affinity towards stromelysin. ChEMBL. 9457244

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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