Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0224 | 0.1322 | 0.1322 |
Leishmania major | hypothetical protein, conserved | 0.0224 | 0.1322 | 0.6806 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0065 | 0.0263 | 0.0263 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0081 | 0.037 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.0302 | 0.1052 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0055 | 0.02 | 0.02 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0067 | 0.0278 | 0.0278 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0055 | 0.02 | 0.02 |
Schistosoma mansoni | ferritin | 0.0036 | 0.0073 | 0.0069 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0241 | 0.0237 |
Mycobacterium leprae | Probable lipase LipE | 0.0224 | 0.1322 | 1 |
Schistosoma mansoni | lamin | 0.0053 | 0.0182 | 0.0178 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0052 | 0.018 | 0.0358 |
Mycobacterium ulcerans | beta-lactamase | 0.0224 | 0.1322 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0224 | 0.1322 | 0.1322 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0182 | 0.1142 |
Toxoplasma gondii | thioredoxin reductase | 0.0053 | 0.0187 | 0.0233 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0241 | 0.1342 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0055 | 0.02 | 0.1227 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0026 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.1322 | 0.8292 |
Brugia malayi | intermediate filament protein | 0.0053 | 0.0182 | 0.1117 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0055 | 0.02 | 0.1481 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0065 | 0.0263 | 0.0204 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0055 | 0.02 | 0.1481 |
Leishmania major | cathepsin L-like protease | 0.0071 | 0.0302 | 0.0896 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0067 | 0.0278 | 0.0278 |
Mycobacterium tuberculosis | Probable reductase | 0.0122 | 0.0644 | 0.0614 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.1322 | 0.8292 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0055 | 0.02 | 0.0195 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0065 | 0.0261 | 0.0819 |
Brugia malayi | RNA binding protein | 0.0061 | 0.0238 | 0.1471 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.1265 | 0.7931 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0238 | 0.0234 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0306 | 0.1874 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0224 | 0.1322 | 0.1318 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0061 | 0.0234 | 0.1468 |
Mycobacterium ulcerans | hypothetical protein | 0.0161 | 0.0907 | 0.6671 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0055 | 0.02 | 0.02 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0055 | 0.02 | 0.1252 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0224 | 0.1322 | 0.1344 |
Schistosoma mansoni | ferritin | 0.0036 | 0.0073 | 0.0069 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0026 | 0.0004 | 0.0028 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0053 | 0.0187 | 0.0187 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0048 | 0.0148 | 0.0148 |
Onchocerca volvulus | 0.0215 | 0.1265 | 0.9563 | |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0055 | 0.02 | 0.0195 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.0241 | 0.0241 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0238 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0028 |
Schistosoma mansoni | coup transcription factor | 0.0055 | 0.02 | 0.0195 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0026 | 0.0004 | 0.0004 |
Echinococcus multilocularis | tumor protein p63 | 0.1469 | 0.9632 | 0.9632 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0472 | 0.2976 | 0.2976 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.0302 | 0.1052 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0081 | 0.037 | 0.181 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0028 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0055 | 0.02 | 0.1227 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0122 | 0.0644 | 0.0614 |
Echinococcus multilocularis | lamin | 0.0053 | 0.0182 | 0.0182 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0028 |
Echinococcus granulosus | lamin | 0.0053 | 0.0182 | 0.0182 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0026 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | DR-78 | 0.0026 | 0.0004 | 0.0028 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0055 | 0.02 | 0.1252 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0055 | 0.02 | 0.1252 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0055 | 0.02 | 0.1481 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0041 | 0.0102 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.02 | 0.1252 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0241 | 0.0237 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0029 | 0.0025 | 0.0131 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0029 | 0.0025 | 0.0025 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0055 | 0.02 | 0.1227 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.0302 | 0.1052 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.0302 | 0.1052 |
Schistosoma mansoni | intermediate filament proteins | 0.0053 | 0.0182 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.02 | 0.1252 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0028 |
Loa Loa (eye worm) | glutathione reductase | 0.0053 | 0.0187 | 0.1172 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0278 | 0.0273 |
Leishmania major | trypanothione reductase | 0.0053 | 0.0187 | 0.0228 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0065 | 0.0263 | 0.152 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0224 | 0.1322 | 0.1344 |
Leishmania major | hypothetical protein, conserved | 0.0081 | 0.037 | 0.1289 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0029 | 0.0025 | 0.0021 |
Trichomonas vaginalis | esterase, putative | 0.0224 | 0.1322 | 1 |
Brugia malayi | glutathione reductase | 0.0053 | 0.0187 | 0.1147 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0048 | 0.0148 | 0.09 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0098 | 0.0485 | 0.3044 |
Plasmodium vivax | hypothetical protein, conserved | 0.0224 | 0.1322 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0053 | 0.0182 | 0.1142 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0048 | 0.0148 | 0.5 |
Brugia malayi | beta-lactamase | 0.0224 | 0.1322 | 0.8288 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.0302 | 0.1052 |
Schistosoma mansoni | ferritin | 0.0036 | 0.0073 | 0.0069 |
Echinococcus granulosus | FTZ F1 alpha | 0.0055 | 0.02 | 0.02 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0029 | 0.0025 | 0.0131 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0122 | 0.0644 | 0.0614 |
Onchocerca volvulus | 0.0224 | 0.1322 | 1 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.0485 | 0.0481 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0061 | 0.0238 | 0.1495 |
Onchocerca volvulus | 0.0055 | 0.02 | 0.1481 | |
Schistosoma mansoni | lamin | 0.0053 | 0.0182 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.02 | 0.1252 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0029 | 0.0025 | 0.0025 |
Echinococcus multilocularis | ferritin | 0.0036 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.02 | 0.1252 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0028 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0278 | 0.0273 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0041 | 0.0102 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.1322 | 0.8292 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0036 | 0.0073 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0028 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0055 | 0.02 | 0.0195 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0028 | 0.0019 | 0.0117 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0055 | 0.02 | 0.02 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0224 | 0.1322 | 0.6861 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0055 | 0.02 | 0.0195 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0278 | 0.0273 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0241 | 0.1342 |
Onchocerca volvulus | 0.0053 | 0.0182 | 0.1347 | |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0224 | 0.1322 | 0.8288 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.0302 | 0.1052 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0071 | 0.0302 | 0.1052 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0055 | 0.02 | 0.1227 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0122 | 0.0644 | 0.0614 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0071 | 0.0302 | 0.1052 |
Onchocerca volvulus | 0.0224 | 0.1322 | 1 | |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0055 | 0.02 | 0.1227 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0406 | 0.254 | 0.254 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0055 | 0.02 | 0.1252 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0048 | 0.0148 | 0.0171 |
Schistosoma mansoni | nuclear hormone receptor | 0.0055 | 0.02 | 0.0195 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0026 | 0.0004 | 0.0004 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0055 | 0.02 | 0.0195 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0122 | 0.0645 | 0.4042 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0224 | 0.1322 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0055 | 0.02 | 0.1252 |
Mycobacterium tuberculosis | Conserved protein | 0.0224 | 0.1322 | 0.1344 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0025 | 0.0131 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0224 | 0.1322 | 0.6861 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0048 | 0.0148 | 0.0148 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0224 | 0.1322 | 0.1318 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0055 | 0.02 | 0.1227 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0055 | 0.02 | 0.1227 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0041 | 0.0102 | 0.0102 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0122 | 0.0644 | 0.4568 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0048 | 0.0148 | 0.0143 |
Schistosoma mansoni | ferritin light chain | 0.0036 | 0.0073 | 0.0069 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0055 | 0.02 | 0.1227 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0224 | 0.1322 | 1 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0048 | 0.0148 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.037 | 0.2321 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0122 | 0.0644 | 0.0614 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0026 | 0.0004 | 0.0028 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0055 | 0.02 | 0.02 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.0241 | 0.0541 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0081 | 0.037 | 0.1439 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.02 | 0.1252 |
Brugia malayi | TAR-binding protein | 0.0061 | 0.0238 | 0.1471 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0055 | 0.02 | 0.1252 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0048 | 0.0148 | 0.0594 |
Brugia malayi | nuclear hormone receptor | 0.0055 | 0.02 | 0.1227 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0036 | 0.0072 | 0.0072 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0055 | 0.02 | 0.02 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0081 | 0.037 | 0.1439 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0122 | 0.0645 | 0.4042 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0055 | 0.02 | 0.0195 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0238 | 0.0234 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.0485 | 0.0481 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0055 | 0.02 | 0.02 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0067 | 0.0278 | 0.1741 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0071 | 0.0302 | 0.1052 |
Mycobacterium ulcerans | hypothetical protein | 0.0224 | 0.1322 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0055 | 0.02 | 0.1227 |
Brugia malayi | beta-lactamase family protein | 0.0224 | 0.1322 | 0.8288 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0067 | 0.0278 | 0.0278 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.0302 | 0.1052 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0055 | 0.02 | 0.1252 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0212 | 0.1244 | 0.7796 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1525 | 1 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0224 | 0.1322 | 0.1344 |
Loa Loa (eye worm) | RNA binding protein | 0.0061 | 0.0238 | 0.1495 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0224 | 0.1322 | 0.1344 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0136 | 0.0735 | 0.0712 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0055 | 0.02 | 0.02 |
Schistosoma mansoni | thyroid hormone receptor | 0.0462 | 0.2909 | 0.2906 |
Echinococcus granulosus | tumor protein p63 | 0.1469 | 0.9632 | 0.9632 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.1322 | 0.8292 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0136 | 0.0735 | 0.0712 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0048 | 0.0148 | 0.0148 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0462 | 0.2909 | 0.2909 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0048 | 0.0148 | 0.0148 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0406 | 0.254 | 0.254 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0224 | 0.1322 | 0.1344 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.0302 | 0.1052 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0306 | 0.1874 | 1 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0025 | 0.0131 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0055 | 0.02 | 0.0195 |
Leishmania major | cathepsin L-like protease | 0.0071 | 0.0302 | 0.0896 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0224 | 0.1322 | 0.1344 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0025 | 0.0159 |
Mycobacterium ulcerans | lipase LipD | 0.0224 | 0.1322 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.1429 | 0.9363 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.02 | 0.1252 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0048 | 0.0148 | 0.0171 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0036 | 0.0072 | 0.0072 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0026 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0028 |
Echinococcus multilocularis | expressed protein | 0.0036 | 0.0073 | 0.0073 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0055 | 0.02 | 0.02 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0055 | 0.02 | 0.02 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0055 | 0.02 | 0.1227 |
Schistosoma mansoni | hypothetical protein | 0.0406 | 0.254 | 0.2537 |
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.1244 | 0.7802 |
Toxoplasma gondii | ABC1 family protein | 0.0224 | 0.1322 | 1 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0065 | 0.0263 | 0.0259 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.0241 | 0.1342 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0055 | 0.02 | 0.02 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0224 | 0.1322 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0029 | 0.0025 | 0.0021 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0048 | 0.0148 | 0.0594 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0055 | 0.02 | 0.1227 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0224 | 0.1322 | 0.1344 |
Schistosoma mansoni | ferritin light chain | 0.0036 | 0.0073 | 0.0069 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0102 | 0.0612 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0055 | 0.02 | 0.02 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0224 | 0.1322 | 0.8292 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0145 | 0.0797 | 0.4983 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0215 | 0.1265 | 0.1261 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.1322 | 0.8292 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0081 | 0.037 | 0.1439 |
Schistosoma mansoni | thyroid hormone receptor | 0.0462 | 0.2909 | 0.2906 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0056 | 0.0201 | 0.0477 |
Echinococcus multilocularis | musashi | 0.0053 | 0.0182 | 0.0182 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0067 | 0.0278 | 0.1718 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0048 | 0.0148 | 0.0143 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.0485 | 0.0481 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0053 | 0.0187 | 0.0122 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0161 | 0.0907 | 0.0897 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0145 | 0.0797 | 0.3764 |
Brugia malayi | MH2 domain containing protein | 0.0122 | 0.0645 | 0.4026 |
Onchocerca volvulus | 0.0053 | 0.0182 | 0.1347 | |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0055 | 0.02 | 0.1227 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0028 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0055 | 0.02 | 0.1227 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0055 | 0.02 | 0.02 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0472 | 0.2976 | 0.2976 |
Echinococcus granulosus | neuropeptide s receptor | 0.0472 | 0.2976 | 0.2976 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0025 | 0.0159 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0061 | 0.0238 | 0.1471 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0071 | 0.0302 | 0.1052 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0025 | 0.0159 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0265 | 0.1595 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0081 | 0.037 | 0.1614 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0055 | 0.02 | 0.02 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0212 | 0.1244 | 0.7802 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0081 | 0.037 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0053 | 0.0187 | 0.1172 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0065 | 0.0263 | 0.0263 |
Schistosoma mansoni | hypothetical protein | 0.0145 | 0.0797 | 0.0793 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.02 | 0.1252 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0224 | 0.1322 | 0.6861 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.0241 | 0.0699 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.1322 | 0.8292 |
Echinococcus granulosus | GPCR family 2 | 0.0067 | 0.0278 | 0.0278 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0055 | 0.02 | 0.02 |
Mycobacterium tuberculosis | Conserved protein | 0.0224 | 0.1322 | 0.1344 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0053 | 0.0187 | 0.0187 |
Brugia malayi | follicle stimulating hormone receptor | 0.0265 | 0.1595 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0224 | 0.1322 | 0.8288 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0028 | 0.0019 | 0.0089 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0031 | 0.0034 | 0.0214 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0055 | 0.02 | 0.1227 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0026 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0028 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0055 | 0.02 | 0.0195 |
Echinococcus granulosus | intermediate filament protein | 0.0053 | 0.0182 | 0.0182 |
Loa Loa (eye worm) | beta-lactamase | 0.0224 | 0.1322 | 0.8292 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0098 | 0.0485 | 0.3025 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0102 | 0.0097 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0212 | 0.1244 | 0.7796 |
Schistosoma mansoni | apoferritin-2 | 0.0036 | 0.0073 | 0.0069 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0145 | 0.0797 | 0.3871 |
Echinococcus multilocularis | tar DNA binding protein | 0.0061 | 0.0238 | 0.0238 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0026 | 0.0004 | 0.0004 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1525 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0055 | 0.02 | 0.1252 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0224 | 0.1322 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0055 | 0.02 | 0.1227 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.0302 | 0.1052 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0238 | 0.0234 |
Schistosoma mansoni | ferritin | 0.0036 | 0.0073 | 0.0069 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0238 | 0.0234 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0026 | 0.0004 | 0.0004 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0098 | 0.0485 | 0.0485 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0224 | 0.1322 | 0.1344 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.0797 | 0.4997 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0026 | 0.0004 | 0.0004 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0048 | 0.0148 | 0.0148 |
Brugia malayi | nuclear receptor RXR | 0.0029 | 0.0025 | 0.0131 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.0241 | 0.0241 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.0302 | 0.1052 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0036 | 0.0073 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0278 | 0.1741 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0224 | 0.1322 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.02 | 0.1252 |
Schistosoma mansoni | apoferritin-2 | 0.0036 | 0.0073 | 0.0069 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0048 | 0.0148 | 1 |
Echinococcus granulosus | ferritin | 0.0036 | 0.0073 | 0.0073 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0065 | 0.0263 | 0.1627 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0067 | 0.0278 | 0.0278 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0072 | 0.0068 |
Brugia malayi | Thioredoxin reductase | 0.0053 | 0.0187 | 0.1147 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0026 | 0.0004 | 0.0004 |
Leishmania major | cathepsin L-like protease | 0.0071 | 0.0302 | 0.0896 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0026 | 0.0004 | 0.0004 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0224 | 0.1322 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0031 | 0.0034 | 0.0186 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0029 | 0.0025 | 0.0159 |
Mycobacterium leprae | conserved hypothetical protein | 0.0224 | 0.1322 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0176 | 0.1101 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0055 | 0.02 | 0.0195 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0055 | 0.02 | 0.02 |
Echinococcus multilocularis | GPCR, family 2 | 0.0067 | 0.0278 | 0.0278 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0136 | 0.0735 | 0.0712 |
Brugia malayi | nuclear receptor NHR-88 | 0.0055 | 0.02 | 0.1227 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0025 | 0.0159 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0179 | 0.1096 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0278 | 0.0273 |
Echinococcus granulosus | tar DNA binding protein | 0.0061 | 0.0238 | 0.0238 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0098 | 0.0485 | 0.0485 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0067 | 0.0278 | 0.1718 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0026 | 0.0004 | 0.0028 |
Loa Loa (eye worm) | TAR-binding protein | 0.0061 | 0.0238 | 0.1495 |
Echinococcus granulosus | lamin dm0 | 0.0053 | 0.0182 | 0.0182 |
Onchocerca volvulus | 0.0224 | 0.1322 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.0302 | 0.1052 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0472 | 0.2976 | 0.2976 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0224 | 0.1322 | 1 |
Echinococcus granulosus | expressed protein | 0.0036 | 0.0073 | 0.0073 |
Brugia malayi | steroid hormone receptor | 0.0055 | 0.02 | 0.1227 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0065 | 0.0263 | 0.152 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0148 | 0.0926 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0055 | 0.02 | 0.1227 |
Echinococcus multilocularis | lamin dm0 | 0.0053 | 0.0182 | 0.0182 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0048 | 0.0148 | 0.0594 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0053 | 0.0182 | 0.1142 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0122 | 0.0644 | 0.0614 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0136 | 0.0735 | 0.5295 |
Brugia malayi | hypothetical protein | 0.0081 | 0.037 | 0.23 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0004 | 0.0028 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0098 | 0.0485 | 0.0485 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0048 | 0.0148 | 0.0171 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0098 | 0.0485 | 0.0485 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0065 | 0.0263 | 0.067 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0026 | 0.0004 | 0.0004 |
Trypanosoma brucei | trypanothione reductase | 0.0053 | 0.0187 | 0.0395 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0145 | 0.0797 | 0.3871 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.0241 | 0.018 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0053 | 0.0187 | 0.0395 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0306 | 0.1874 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0055 | 0.02 | 0.1227 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0025 | 0.0159 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0306 | 0.1874 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0053 | 0.0182 | 0.1117 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.