Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.1168 | 0.2229 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0011 | 0.1168 | 0.2229 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0239 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0339 | 0.0239 |
Plasmodium falciparum | zinc finger protein, putative | 0.0004 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.1168 | 0.2229 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0006 | 0.0339 | 0.0223 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0651 | 0.0651 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.4403 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.1168 | 0.2229 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.1168 | 0.2086 |
Onchocerca volvulus | 0.0031 | 0.4403 | 1 | |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0651 | 0.0925 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0005 | 0.024 | 0.024 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.1168 | 0.2086 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.1168 | 0.2086 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.1168 | 0.2086 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.1168 | 0.2229 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0239 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.1168 | 0.2086 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.1168 | 0.2086 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0239 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.1168 | 0.2229 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.1168 | 0.2229 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.1168 | 0.1168 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.1609 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.1168 | 0.1168 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.1168 | 0.2229 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.1168 | 0.1168 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.2229 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.1168 | 0.2229 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.1168 | 0.2229 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.1168 | 0.1168 |
Onchocerca volvulus | 0.0011 | 0.1168 | 0.2229 | |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0004 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.024 | 0.024 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.1168 | 0.2086 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.1168 | 0.2086 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.1168 | 0.2229 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.1168 | 0.2229 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0011 | 0.1168 | 0.2229 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.4403 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.1168 | 0.2229 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.1168 | 0.1168 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.4688 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.1168 | 0.2229 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.2229 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0339 | 0.0239 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.1168 | 0.2229 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.1168 | 0.1168 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.1168 | 0.2086 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0956 | 0.1719 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.1168 | 0.2229 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.1168 | 0.1168 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.024 | 0.024 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0127 | 0.0127 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.1168 | 0.2086 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0936 | 0.1672 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.1168 | 0.2229 |
Schistosoma mansoni | zinc finger protein | 0.0005 | 0.024 | 0.024 |
Brugia malayi | nuclear receptor RXR | 0.0006 | 0.0339 | 0.0239 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.1168 | 0.1168 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0005 | 0.024 | 0.024 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.1168 | 0.1168 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.024 | 0.024 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0651 | 0.0925 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.1168 | 0.2229 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0011 | 0.1168 | 0.2229 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0651 | 0.0925 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.4403 | 0.4403 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.2229 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.1168 | 0.1168 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4688 | 0.4688 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0006 | 0.0339 | 0.0239 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0005 | 0.024 | 0.024 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.8869 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0339 | 0.0239 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.1168 | 0.1168 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0651 | 0.0925 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.1168 | 0.2086 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.1168 | 0.2229 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4688 | 0.4688 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.2229 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.1168 | 0.2086 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.1168 | 0.2229 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0542 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.1168 | 0.2086 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.1168 | 0.2229 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.2229 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.1168 | 0.1168 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.2229 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.024 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.2229 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.1168 | 0.2229 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.1168 | 0.2229 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0339 | 0.0239 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.1168 | 0.2086 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0239 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.1168 | 0.2229 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0006 | 0.0339 | 0.0339 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.1168 | 0.2229 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.1168 | 0.2086 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.1168 | 0.1168 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.1168 | 0.2229 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.1168 | 0.2086 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.1168 | 0.2229 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.1168 | 0.2229 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.1168 | 0.2086 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0006 | 0.0339 | 0.0339 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0339 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1168 | 0.2229 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.1609 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.1168 | 0.2229 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.1168 | 0.2086 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0006 | 0.0339 | 0.0223 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.4688 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.