Detailed information for compound 1163696

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 296.34 | Formula: C18H18NO3+
  • H donors: 0 H acceptors: 0 LogP: 3.5 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCCc1ccc2c(c1)c1ccc3c(c1c[n+]2C)OCO3
  • InChi: 1S/C18H18NO3/c1-19-10-15-13(4-6-17-18(15)22-11-21-17)14-9-12(7-8-20-2)3-5-16(14)19/h3-6,9-10H,7-8,11H2,1-2H3/q+1
  • InChiKey: JVMZFTPPNPKBFK-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.1316 0.3658 0.841
Entamoeba histolytica cysteine protease, putative 0.0363 0.0987 0.5373
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.0491 0.1128
Plasmodium falciparum serine repeat antigen 1 0.0158 0.0412 0.2218
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0363 0.0987 0.2269
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0271 0.0728 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0158 0.0412 0.0946
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.003 0.0052 0.0248
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0664 0.1831 1
Treponema pallidum fructose-bisphosphate aldolase 0.0555 0.1524 1
Echinococcus granulosus expressed protein 0.0044 0.0093 0.0213
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0664 0.1831 1
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0066 0.0137
Schistosoma mansoni hypothetical protein 0.0108 0.0271 0.0624
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0044 0.0093 0.1184
Echinococcus multilocularis cathepsin L 0.0158 0.0412 0.0412
Loa Loa (eye worm) hypothetical protein 0.0035 0.0067 0.0151
Schistosoma mansoni inositol monophosphatase 0.0043 0.009 0.0208
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0491 0.1128
Brugia malayi Papain family cysteine protease containing protein 0.0158 0.0412 0.0946
Schistosoma mansoni aldehyde dehydrogenase 0.0071 0.0169 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0592 0.163 0.8901
Loa Loa (eye worm) aminopeptidase in chromosome V 0.0041 0.0083 0.0189
Schistosoma mansoni transient receptor potential channel 4 0.0095 0.0235 0.054
Loa Loa (eye worm) hypothetical protein 0.0035 0.0066 0.0151
Giardia lamblia Histone acetyltransferase GCN5 0.0035 0.0067 0.0296
Brugia malayi Cathepsin L-like cysteine proteinase 0.0459 0.1256 0.2886
Onchocerca volvulus 0.0048 0.0103 0.0526
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0061 0.0817
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0066 0.0152
Giardia lamblia Cathepsin L precursor 0.0158 0.0412 0.2435
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0007 0.0016
Loa Loa (eye worm) aminopeptidase in chromosome III 0.0041 0.0083 0.0189
Brugia malayi Cathepsin L-like precursor 0.0664 0.1831 0.4209
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.003 0.0052 0.0248
Loa Loa (eye worm) isocitrate dehydrogenase 0.003 0.0052 0.0119
Echinococcus multilocularis musashi 0.0092 0.0227 0.0227
Mycobacterium tuberculosis Conserved protein 0.0035 0.0066 0.089
Entamoeba histolytica hypothetical protein 0.0124 0.0316 0.1693
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0664 0.1831 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0664 0.1831 1
Brugia malayi intermediate filament protein 0.0092 0.0227 0.052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0555 0.1524 0.8323
Entamoeba histolytica cysteine protease, putative 0.0363 0.0987 0.5373
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0015 0.0012 0.0012
Giardia lamblia Cysteine protease 0.0158 0.0412 0.2435
Loa Loa (eye worm) hypothetical protein 0.0025 0.0038 0.0087
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.009 0.0235
Echinococcus granulosus methyl CpG binding domain protein 2 0.0016 0.0013 0.0031
Loa Loa (eye worm) hypothetical protein 0.0158 0.0412 0.0945
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.002 0.0069
Loa Loa (eye worm) hypothetical protein 0.0047 0.01 0.0227
Onchocerca volvulus 0.0028 0.0047 0.0219
Schistosoma mansoni lamin 0.0092 0.0227 0.0521
Entamoeba histolytica cysteine protease, putative 0.0158 0.0412 0.2218
Brugia malayi Papain family cysteine protease containing protein 0.0363 0.0987 0.2269
Schistosoma mansoni cathepsin B (C01 family) 0.0158 0.0412 0.0946
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0079 0.0428
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0066 0.0359
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0038 0.0172
Loa Loa (eye worm) hypothetical protein 0.0459 0.1256 0.2885
Loa Loa (eye worm) hypothetical protein 0.0035 0.0067 0.0151
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0083 0.0413
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0205 0.0543 0.1233
Brugia malayi Inositol-1 0.0043 0.009 0.0207
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.0007 0.0074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0664 0.1831 1
Toxoplasma gondii hypothetical protein 0.0046 0.0099 0.0504
Loa Loa (eye worm) hypothetical protein 0.0044 0.0093 0.0213
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0592 0.163 0.3736
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0066 0.0822
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0011 0.0001 0.0001
Echinococcus multilocularis tumor protein p63 0.0327 0.0886 0.0886
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0047 0.0217
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0444 0.2424
Echinococcus multilocularis voltage gated potassium channel 0.0015 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0444 0.2424
Giardia lamblia Cathepsin B precursor 0.0158 0.0412 0.2435
Schistosoma mansoni survival motor neuron protein 0.0268 0.0721 0.1658
Leishmania major mitochondrial DNA polymerase beta 0.0288 0.0777 0.2168
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0158 0.0412 0.2218
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.01 0.1282
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0007 0.0074
Echinococcus granulosus histone acetyltransferase KAT2B 0.0127 0.0324 0.0746
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0664 0.1831 0.4208
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0158 0.0412 0.2218
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0444 0.2424
Echinococcus granulosus short transient receptor potential channel 6 0.0064 0.0147 0.0339
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.0694 0.3786
Brugia malayi Cathepsin L-like precursor 0.0205 0.0544 0.125
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0158 0.0412 0.2435
Onchocerca volvulus Huntingtin homolog 0.0138 0.0355 0.1907
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.01 0.1282
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0066 0.089
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0124 0.0316 0.0316
Plasmodium falciparum importin beta, putative 0.0028 0.0047 0.0217
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0049 0.0107 0.0244
Mycobacterium ulcerans hypothetical protein 0.0035 0.0066 0.0822
Echinococcus multilocularis isocitrate dehydrogenase 0.003 0.0052 0.0052
Brugia malayi Pre-SET motif family protein 0.0028 0.0047 0.0108
Echinococcus multilocularis cpg binding protein 0.0031 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0158 0.0412 0.2246
Toxoplasma gondii cathepsin CPL 0.0664 0.1831 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0001 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0363 0.0987 0.2759
Brugia malayi Cathepsin L-like precursor 0.0664 0.1831 0.4209
Loa Loa (eye worm) hypothetical protein 0.0035 0.0067 0.0151
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0664 0.1831 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0092 0.0211
Entamoeba histolytica cysteine proteinase, putative 0.0363 0.0987 0.5373
Brugia malayi hypothetical protein 0.0138 0.0355 0.0815
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.009 0.009
Echinococcus granulosus GPCR family 2 0.0108 0.0271 0.0624
Brugia malayi hypothetical protein 0.0025 0.0038 0.0088
Echinococcus multilocularis cathepsin b 0.1562 0.435 0.435
Brugia malayi cathepsin L precursor 0.0158 0.0412 0.0946
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.002 0.0035
Echinococcus multilocularis transient receptor potential ion channel A 0.0089 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.0035 0.0066 0.0151
Plasmodium vivax vivapain-1 0.0363 0.0987 0.5373
Brugia malayi Papain family cysteine protease containing protein 0.0363 0.0987 0.2269
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0664 0.1831 1
Trichomonas vaginalis ferritin, putative 0.0044 0.0093 0.0502
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0044 0.0093 0.1249
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0007 0.0074
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0001 0.0002
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0015 0.0012 0.0027
Brugia malayi CXXC zinc finger family protein 0.0028 0.0047 0.0106
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0271 0.0728 1
Echinococcus granulosus cathepsin L cysteine protease 0.0363 0.0987 0.2269
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0007 0.0015
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0082 0.0173
Schistosoma mansoni leucine aminopeptidase 0.0041 0.0083 0.0191
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0032 0.0074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.128 0.3559 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0363 0.0987 0.5389
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0158 0.0412 0.2246
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0037 0.0073 0.0073
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0066 0.089
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0158 0.0412 0.2218
Schistosoma mansoni cathepsin F (C01 family) 0.0664 0.1831 0.4209
Leishmania major cathepsin L-like protease 0.0664 0.1831 0.5135
Brugia malayi cathepsin F-like cysteine proteinase 0.0205 0.0544 0.125
Mycobacterium ulcerans bacterioferritin BfrB 0.0044 0.0093 0.1184
Entamoeba histolytica cysteine protease, putative 0.0363 0.0987 0.5373
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0158 0.0412 0.0946
Plasmodium falciparum serine repeat antigen 8 0.0158 0.0412 0.2218
Leishmania major hypothetical protein, conserved 0.0035 0.0066 0.0167
Entamoeba histolytica hypothetical protein 0.0158 0.0412 0.2218
Loa Loa (eye worm) hypothetical protein 0.0035 0.0067 0.0151
Schistosoma mansoni cathepsin F (C01 family) 0.0459 0.1256 0.2886
Loa Loa (eye worm) hypothetical protein 0.0158 0.0412 0.0945
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.0694 0.3786
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.003 0.0052 0.0052
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.002 0.0173
Echinococcus granulosus cathepsin b 0.1562 0.435 1
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.0694 0.3786
Brugia malayi Cathepsin L-like precursor 0.0664 0.1831 0.4209
Schistosoma mansoni apoferritin-2 0.0044 0.0093 0.0213
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0555 0.1524 0.8317
Loa Loa (eye worm) hypothetical protein 0.0095 0.0235 0.0539
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0592 0.163 0.3746
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.002 0.0029
Brugia malayi hypothetical protein 0.0016 0.0014 0.0031
Entamoeba histolytica cysteine protease, putative 0.0158 0.0412 0.2218
Entamoeba histolytica cysteine proteinase, putative 0.0459 0.1256 0.6845
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.01 0.1282
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0016 0.0013 0.0013
Schistosoma mansoni cathepsin s 0.0205 0.0544 0.1251
Trypanosoma cruzi major cysteine proteinase, putative 0.0158 0.0412 0.0932
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1562 0.435 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.009 0.0457
Brugia malayi cytosol aminopeptidase 0.0041 0.0083 0.019
Loa Loa (eye worm) transcription factor SMAD2 0.0134 0.0345 0.0792
Brugia malayi Cathepsin L-like precursor 0.0664 0.1831 0.4209
Schistosoma mansoni hypothetical protein 0.0626 0.1725 0.3965
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0158 0.0412 0.2435
Echinococcus multilocularis cysteine protease 0.0664 0.1831 0.1831
Brugia malayi Papain family cysteine protease containing protein 0.0664 0.1831 0.4209
Giardia lamblia Hypothetical protein 0.0158 0.0412 0.2435
Brugia malayi Aminopeptidase ZK353.6 in chromosome III 0.0041 0.0083 0.019
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0108 0.0271 0.0624
Brugia malayi cathepsin B-like cysteine proteinase 0.1562 0.435 1
Schistosoma mansoni ferritin light chain 0.0044 0.0093 0.0213
Loa Loa (eye worm) hypothetical protein 0.0058 0.0131 0.03
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0205 0.0543 0.7442
Plasmodium falciparum serine repeat antigen 2 0.0158 0.0412 0.2218
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0664 0.1831 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0066 0.0153
Trypanosoma cruzi cysteine peptidase, putative 0.0205 0.0544 0.1236
Loa Loa (eye worm) hypothetical protein 0.0138 0.0355 0.0815
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0664 0.1831 1
Toxoplasma gondii cathepsin CPC2 0.0158 0.0412 0.2218
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0158 0.0412 0.0946
Loa Loa (eye worm) hypothetical protein 0.0158 0.0412 0.0945
Plasmodium falciparum M17 leucyl aminopeptidase 0.0205 0.0543 0.2936
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0007 0.0007
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0136 0.0351 0.0969
Echinococcus granulosus transient receptor potential ion channel A 0.0089 0.0219 0.0502
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0158 0.0412 0.0945
Brugia malayi isocitrate dehydrogenase 0.003 0.0052 0.012
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0158 0.0412 0.0946
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0664 0.1831 1
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.003 0.0052 0.0127
Entamoeba histolytica cysteine proteinase, putative 0.0664 0.1831 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0158 0.0412 0.2246
Schistosoma mansoni zinc finger protein 0.0014 0.0009 0.002
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0297 0.0802 0.1843
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0158 0.0412 0.2218
Onchocerca volvulus 0.0218 0.0579 0.3138
Entamoeba histolytica hypothetical protein 0.0124 0.0316 0.1693
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0664 0.1831 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0191 0.0506 0.1161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0664 0.1831 1
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.0007 0.0074
Schistosoma mansoni ferritin 0.0044 0.0093 0.0213
Echinococcus multilocularis cathepsin L cysteine protease 0.0664 0.1831 0.1831
Treponema pallidum bacterioferrin (TpF1) 0.0044 0.0093 0.0485
Onchocerca volvulus 0.0664 0.1831 1
Onchocerca volvulus 0.0664 0.1831 1
Schistosoma mansoni cathepsin F (C01 family) 0.0664 0.1831 0.4209
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0001 0.0002
Trypanosoma cruzi major cysteine proteinase, putative 0.0774 0.214 0.4911
Entamoeba histolytica cysteine proteinase, putative 0.0363 0.0987 0.5373
Schistosoma mansoni hypothetical protein 0.0108 0.0271 0.0624
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0158 0.0412 0.2218
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0028 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0044 0.0092 0.0209
Brugia malayi Papain family cysteine protease containing protein 0.0158 0.0412 0.0946
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0044 0.0093 0.1249
Echinococcus multilocularis short transient receptor potential channel 6 0.0064 0.0147 0.0147
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.01 0.0507
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0664 0.1831 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.002 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0555 0.1524 0.8323
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0066 0.0359
Echinococcus granulosus ankyrin repeat domain containing protein 17 0.0041 0.0083 0.0191
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0007 0.0016
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0066 0.089
Brugia malayi Transient-receptor-potential like protein 0.0037 0.0073 0.0166
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.004 0.008 0.0182
Trypanosoma brucei isocitrate dehydrogenase, putative 0.003 0.0052 0.0127
Loa Loa (eye worm) hypothetical protein 0.0459 0.1256 0.2885
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0007 0.0016
Onchocerca volvulus 0.0664 0.1831 1
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0007 0.0016
Loa Loa (eye worm) hypothetical protein 0.0035 0.0066 0.0151
Onchocerca volvulus 0.0092 0.0227 0.1203
Leishmania major cathepsin L-like protease 0.128 0.3559 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0158 0.0412 0.2435
Onchocerca volvulus 0.0268 0.0721 0.3916
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0066 0.0359
Brugia malayi fibroinase precursor 0.0158 0.0412 0.0946
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0268 0.0721 0.1657
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0033 0.0063 0.0144
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0158 0.0412 0.0946
Mycobacterium ulcerans beta-lactamase 0.0035 0.0066 0.0822
Loa Loa (eye worm) latrophilin receptor protein 2 0.0108 0.0271 0.0622
Echinococcus multilocularis geminin 0.0626 0.1725 0.1725
Onchocerca volvulus 0.0035 0.0066 0.0325
Loa Loa (eye worm) cathepsin B 0.0592 0.163 0.3745
Brugia malayi AMP-binding enzyme family protein 0.0047 0.01 0.0228
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.009 0.049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0664 0.1831 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0491 0.1128
Giardia lamblia Cathepsin L-like protease 0.0158 0.0412 0.2435
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0363 0.0987 0.2269
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0592 0.163 0.4568
Loa Loa (eye worm) hypothetical protein 0.0158 0.0412 0.0945
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0186 0.0491 0.1126
Echinococcus granulosus cathepsin L 0.0158 0.0412 0.0946
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.0007 0.0074
Giardia lamblia Cysteine protease 0.0158 0.0412 0.2435
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0664 0.1831 0.1831
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0258 0.0694 0.1593
Plasmodium vivax unspecified product 0.0158 0.0412 0.2218
Onchocerca volvulus Cathepsin L homolog 0.0664 0.1831 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0664 0.1831 0.4208
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.01 0.0507
Mycobacterium tuberculosis Conserved protein 0.0035 0.0066 0.089
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.002 0.0069
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0013 0.0031
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0124 0.0316 0.0726
Trypanosoma cruzi cruzipain precursor, putative 0.128 0.3559 0.8179
Onchocerca volvulus 0.0664 0.1831 1
Leishmania major cathepsin L-like protease 0.128 0.3559 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0555 0.1524 0.8323
Trypanosoma cruzi cysteine proteinase, putative 0.0363 0.0987 0.2256
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0664 0.1831 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.002 0.0044
Echinococcus multilocularis survival motor neuron protein 1 0.1316 0.3658 0.3658
Echinococcus multilocularis leucyl aminopeptidase 0.0041 0.0083 0.0083
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0011 0.0001 0.0001
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0082 0.0212
Loa Loa (eye worm) hypothetical protein 0.0158 0.0412 0.0945
Toxoplasma gondii leucyl aminopeptidase LAP 0.0205 0.0543 0.2936
Schistosoma mansoni apoferritin-2 0.0044 0.0093 0.0213
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0158 0.0412 0.2246
Loa Loa (eye worm) hypothetical protein 0.0048 0.0103 0.0235
Echinococcus multilocularis snurportin 1 0.0297 0.0802 0.0802
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.01 0.026
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0071 0.0169 0.2299
Mycobacterium ulcerans lipase LipD 0.0035 0.0066 0.0822
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0444 0.2424
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0001 0.0002
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0028 0.0047 0.0219
Schistosoma mansoni cpg binding protein 0.0031 0.0056 0.0129
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0341 0.0925 0.2127
Loa Loa (eye worm) oxidoreductase 0.0014 0.0007 0.0015
Echinococcus granulosus tumor protein p63 0.0327 0.0886 0.2037
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0049 0.0107 0.023
Brugia malayi Papain family cysteine protease containing protein 0.0158 0.0412 0.0946
Entamoeba histolytica cysteine protease, putative 0.0363 0.0987 0.5373
Schistosoma mansoni lamin 0.0092 0.0227 0.0521
Echinococcus multilocularis cathepsin L 0.0363 0.0987 0.0987
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.0593 0.814
Toxoplasma gondii exonuclease III APE 0.0018 0.002 0.0069
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0067 0.0891
Leishmania major cysteine peptidase A (CPA) 0.0664 0.1831 0.5135
Toxoplasma gondii cathepsin CPC1 0.0158 0.0412 0.2218
Leishmania major cathepsin L-like protease 0.0664 0.1831 0.5135
Mycobacterium ulcerans hypothetical protein 0.0152 0.0394 0.537
Onchocerca volvulus 0.0459 0.1256 0.6845
Brugia malayi Cathepsin L-like precursor 0.0459 0.1256 0.2886
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0032 0.0074
Loa Loa (eye worm) beta-lactamase 0.0035 0.0066 0.0151
Trypanosoma cruzi ISWI complex protein 0.0014 0.0009 0.0004
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0038 0.0072
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0038 0.0172
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0083 0.0447
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0205 0.0543 0.2936
Entamoeba histolytica hypothetical protein 0.0124 0.0316 0.1693
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0555 0.1524 0.8323
Plasmodium falciparum serine repeat antigen 7 0.0158 0.0412 0.2218
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0001 0.0001
Loa Loa (eye worm) intermediate filament protein 0.0092 0.0227 0.0519
Plasmodium falciparum serine repeat antigen 9 0.0158 0.0412 0.2218
Loa Loa (eye worm) hypothetical protein 0.0205 0.0544 0.1249
Entamoeba histolytica cysteine proteinase, putative 0.0363 0.0987 0.5373
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0158 0.0412 0.2218
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0024 0.0053
Loa Loa (eye worm) hypothetical protein 0.0035 0.0066 0.0151
Schistosoma mansoni transient receptor potential channel 0.0064 0.0147 0.0339
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0066 0.0325
Entamoeba histolytica hypothetical protein 0.0023 0.0032 0.0136
Giardia lamblia Cathepsin L precursor 0.0158 0.0412 0.2435
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.003 0.0052 0.0104
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.01 0.026
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0007 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0092 0.0211
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.01 0.1346
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0066 0.0137
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.002 0.0104
Schistosoma mansoni cathepsin S (C01 family) 0.0158 0.0412 0.0946
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.128 0.3559 1
Entamoeba histolytica cysteine protease, putative 0.0158 0.0412 0.2218
Plasmodium vivax vivapain-2 0.0664 0.1831 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0044 0.0093 0.0214
Entamoeba histolytica cysteine protease, putative 0.0363 0.0987 0.5373
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0363 0.0987 0.5389
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0555 0.1524 0.8317
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0555 0.1524 0.8323
Schistosoma mansoni bromodomain containing protein 0.0064 0.0147 0.0339
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.009 0.0192
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0007 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.047 0.2564
Entamoeba histolytica cysteine protease, putative 0.0363 0.0987 0.5373
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1562 0.435 1
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0041 0.0083 0.0214
Echinococcus granulosus cysteine protease 0.0363 0.0987 0.2269
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.003 0.0052 0.0127
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.128 0.3559 1
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0041 0.0083 0.0214
Loa Loa (eye worm) hypothetical protein 0.0035 0.0066 0.0151
Mycobacterium tuberculosis Conserved protein 0.0035 0.0066 0.089
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0045 0.0095 0.0219
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.002 0.0246
Loa Loa (eye worm) hypothetical protein 0.0031 0.0056 0.0128
Onchocerca volvulus 0.0035 0.0066 0.0325
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0007 0.0074
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0138 0.0138
Schistosoma mansoni PwLAP aminopeptidase (M17 family) 0.0041 0.0083 0.0191
Leishmania major cathepsin L-like protease 0.0664 0.1831 0.5135
Echinococcus multilocularis ferritin 0.0044 0.0093 0.0093
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0083 0.0413
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.003 0.0052 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.1256 0.6856
Giardia lamblia Cysteine protease 0.0158 0.0412 0.2435
Echinococcus granulosus intermediate filament protein 0.0092 0.0227 0.0521
Schistosoma mansoni transient receptor potential channel 0.0095 0.0235 0.054
Loa Loa (eye worm) hypothetical protein 0.0459 0.1256 0.2885
Echinococcus granulosus voltage gated potassium channel 0.0015 0.0012 0.0027
Toxoplasma gondii cathepsin B 0.0592 0.163 0.8897
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.01 0.0507
Echinococcus multilocularis cathepsin L cysteine protease 0.0664 0.1831 0.1831
Loa Loa (eye worm) PHD-finger family protein 0.0019 0.0023 0.005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0025
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0158 0.0412 0.0946
Giardia lamblia Cathepsin L precursor 0.0158 0.0412 0.2435
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0158 0.0412 0.2246
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0158 0.0412 0.2246
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0026 0.0043 0.0098
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0341 0.0925 0.2126
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0066 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0158 0.0412 0.2246
Loa Loa (eye worm) hypothetical protein 0.0045 0.0094 0.0214
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0083 0.0447
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0169 0.2242
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0137 0.0314
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0555 0.1524 0.8323
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1075 0.2984 0.6854
Trypanosoma cruzi cysteine peptidase, putative 0.128 0.3559 0.8179
Loa Loa (eye worm) hypothetical protein 0.0092 0.0227 0.0519
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.002 0.0045
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0092 0.0227 0.0519
Brugia malayi latrophilin 2 splice variant baaae 0.0233 0.0623 0.1431
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0082 0.0173
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0061 0.0817
Schistosoma mansoni hypothetical protein 0.0233 0.0623 0.1431
Brugia malayi Cathepsin L-like precursor 0.0459 0.1256 0.2886
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0045 0.0095 0.0218
Brugia malayi cathepsin Z-like cysteine proteinase 0.0158 0.0412 0.0946
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.009 0.049
Plasmodium vivax unspecified product 0.0205 0.0544 0.2944
Entamoeba histolytica acetyltransferase, GNAT family 0.0035 0.0067 0.033
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0013 0.0031
Brugia malayi Cathepsin L-like precursor 0.0664 0.1831 0.4209
Schistosoma mansoni ferritin 0.0044 0.0093 0.0213
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.009 0.0222 0.0508
Echinococcus granulosus lamin dm0 0.0092 0.0227 0.0521
Brugia malayi Importin beta-1 subunit 0.0028 0.0047 0.0107
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0158 0.0412 0.0945
Brugia malayi cathepsin Z-like cysteine proteinase 0.0158 0.0412 0.0946
Echinococcus granulosus snurportin 1 0.0297 0.0802 0.1844
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0363 0.0987 0.2269
Entamoeba histolytica cysteine protease, putative 0.0158 0.0412 0.2218
Brugia malayi Aminopeptidase W07G4.4 in chromosome V 0.0041 0.0083 0.019
Mycobacterium ulcerans bacterioferritin BfrA 0.0044 0.0093 0.1184
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0288 0.0777 0.1773
Chlamydia trachomatis cytosol aminopeptidase 0.0205 0.0543 1
Toxoplasma gondii isocitrate dehydrogenase 0.003 0.0052 0.0248
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.0491 0.0491
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.128 0.3559 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0664 0.1831 1
Plasmodium falciparum serine repeat antigen 5 0.0158 0.0412 0.2218
Leishmania major hypothetical protein, conserved 0.0014 0.0009 0.0004
Leishmania major cathepsin L-like protease 0.0664 0.1831 0.5135
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0186 0.0491 0.1127
Echinococcus multilocularis expressed protein 0.0044 0.0093 0.0093
Entamoeba histolytica cysteine protease, putative 0.0363 0.0987 0.5373
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0288 0.0777 0.2168
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0082 0.0173
Loa Loa (eye worm) hypothetical protein 0.0035 0.0066 0.0151
Plasmodium falciparum serine repeat antigen 4 0.0158 0.0412 0.2218
Entamoeba histolytica cysteine protease, putative 0.0363 0.0987 0.5373
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0459 0.1256 0.6856
Echinococcus granulosus leucyl aminopeptidase 0.0041 0.0083 0.0191
Trypanosoma cruzi cysteine peptidase, putative 0.128 0.3559 0.8179
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0038 0.0088
Echinococcus multilocularis GPCR, family 2 0.0108 0.0271 0.0271
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0041 0.0083 0.0214
Onchocerca volvulus 0.0092 0.0227 0.1203
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0133 0.0341 0.0784
Echinococcus granulosus zinc finger protein 0.0023 0.0033 0.0076
Loa Loa (eye worm) hypothetical protein 0.0138 0.0355 0.0815
Mycobacterium tuberculosis Conserved hypothetical protein 0.0152 0.0394 0.5404
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0664 0.1831 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0158 0.0412 0.2246
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0001 0.0002
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.003 0.0052 0.012
Echinococcus granulosus leucyl aminopeptidase 0.0041 0.0083 0.0191
Plasmodium vivax serine-repeat antigen (SERA) 0.0158 0.0412 0.2218
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.009 0.0457
Loa Loa (eye worm) hypothetical protein 0.0205 0.0544 0.1249
Schistosoma mansoni hypothetical protein 0.0268 0.0721 0.1658
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0066 0.089
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0664 0.1831 0.1831
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0664 0.1831 1
Plasmodium vivax unspecified product 0.0363 0.0987 0.5373
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0169 0.2242
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0032 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.128 0.3559 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0158 0.0412 0.2218
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0071 0.0169 0.0169
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.009 0.0192
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0108 0.0271 0.0623
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0066 0.0153
Giardia lamblia Cathepsin B precursor 0.0158 0.0412 0.2435
Schistosoma mansoni hypothetical protein 0.0297 0.0802 0.1844
Schistosoma mansoni hypothetical protein 0.0108 0.0271 0.0624
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0028 0.0047 0.0108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.128 0.3559 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0555 0.1524 0.9343
Trypanosoma cruzi cruzipain precursor, putative 0.0205 0.0544 0.1236
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0158 0.0412 0.2246
Echinococcus granulosus lamin 0.0092 0.0227 0.0521
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0071 0.0169 0.0455
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.0694 0.3786
Echinococcus granulosus geminin 0.0626 0.1725 0.3965
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0664 0.1831 1
Brugia malayi Cathepsin L-like precursor 0.0664 0.1831 0.4209
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0061 0.0817
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0015
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.01 0.1282
Loa Loa (eye worm) hypothetical protein 0.0041 0.0084 0.0192
Echinococcus granulosus cathepsin b 0.1562 0.435 1
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0066 0.0167
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0066 0.0822
Giardia lamblia Cathepsin B precursor 0.0158 0.0412 0.2435
Brugia malayi beta-lactamase family protein 0.0035 0.0066 0.0152
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.128 0.3559 1
Trichomonas vaginalis set domain proteins, putative 0.0218 0.0579 0.3163
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0136 0.0351 0.0969
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.009 0.0208
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0271 0.0728 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.003 0.0052 0.0052
Brugia malayi acetyltransferase, GNAT family protein 0.0133 0.0341 0.0783
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0205 0.0543 0.1507
Onchocerca volvulus Huntingtin homolog 0.0138 0.0355 0.1907
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0158 0.0412 0.2218
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0045 0.0095 0.0219
Echinococcus granulosus cathepsin l1 0.0664 0.1831 0.4209
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0444 0.2424
Schistosoma mansoni intermediate filament proteins 0.0092 0.0227 0.0521
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.002 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0158 0.0412 0.2246
Onchocerca volvulus 0.0664 0.1831 1
Echinococcus granulosus short transient receptor potential channel 6 0.0064 0.0147 0.0339
Giardia lamblia Cysteine protease 0.0158 0.0412 0.2435
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.003 0.0052 0.0695
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0032 0.0057
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0044 0.0092 0.0092
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0133 0.0341 0.0341
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0205 0.0544 0.1249
Leishmania major importin beta-1 subunit, putative 0.0023 0.0032 0.007
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0039 0.0078 0.1045
Schistosoma mansoni cpg binding protein 0.0031 0.0056 0.0129
Onchocerca volvulus 0.0664 0.1831 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.128 0.3559 1
Mycobacterium leprae Probable lipase LipE 0.0035 0.0066 0.0822
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0001 0.0002
Brugia malayi Pre-SET motif family protein 0.0191 0.0506 0.1162
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0158 0.0412 0.0946
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0001 0.0002
Onchocerca volvulus Cathepsin F homolog 0.0664 0.1831 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0158 0.0412 0.0946
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.0694 0.3786
Entamoeba histolytica cysteine proteinase 1, putative 0.0363 0.0987 0.5373
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.0491 0.0491
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.003 0.0052 0.012
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0007 0.0035
Entamoeba histolytica cysteine protease, putative 0.0664 0.1831 1
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0205 0.0544 0.125
Leishmania major cathepsin L-like protease 0.128 0.3559 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0158 0.0412 0.2218
Loa Loa (eye worm) ctsf protein 0.0664 0.1831 0.4208
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0158 0.0412 0.2218
Entamoeba histolytica cysteine protease, putative 0.0158 0.0412 0.2218
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0158 0.0412 0.2218
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0108 0.0271 0.0271
Plasmodium falciparum cysteine proteinase falcipain 1 0.0363 0.0987 0.5373
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.003 0.0052 0.0104
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0083 0.0413
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0158 0.0412 0.0945
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0066 0.0359
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0011 0.0001 0.0002
Entamoeba histolytica cysteine protease, putative 0.0363 0.0987 0.5373
Echinococcus granulosus cathepsin l cysteine peptidase 0.0664 0.1831 0.4209
Leishmania major cathepsin L-like protease 0.0664 0.1831 0.5135
Giardia lamblia Hypothetical protein 0.0158 0.0412 0.2435
Brugia malayi Intermediate filament tail domain containing protein 0.0092 0.0227 0.052
Echinococcus multilocularis cysteine protease 0.0664 0.1831 0.1831
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0038 0.0072
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0007 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0664 0.1831 1
Loa Loa (eye worm) hypothetical protein 0.1316 0.3658 0.8409
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0258 0.0694 0.1594
Trypanosoma cruzi cysteine protease, putative 0.0363 0.0987 0.2256
Echinococcus multilocularis leucyl aminopeptidase 0.0041 0.0083 0.0083
Mycobacterium ulcerans leucyl aminopeptidase 0.0205 0.0543 0.7423
Trypanosoma cruzi cysteine peptidase, putative 0.0664 0.1831 0.4199
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0066 0.0359
Schistosoma mansoni hypothetical protein 0.0626 0.1725 0.3965
Plasmodium falciparum serine repeat antigen 6 0.0158 0.0412 0.2218
Echinococcus multilocularis transient receptor potential gamma protein 0.0095 0.0235 0.0235
Echinococcus granulosus cathepsin L cysteine proteinase 0.0664 0.1831 0.4209
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0158 0.0412 0.2218
Onchocerca volvulus 0.0047 0.01 0.0507
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0158 0.0412 0.2246
Entamoeba histolytica cysteine protease, putative 0.0363 0.0987 0.5373
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.003 0.0052 0.0052
Echinococcus multilocularis leucine aminopeptidase protein 0.0205 0.0543 0.0543
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0158 0.0412 0.2246
Giardia lamblia Cathepsin L-like protease 0.0158 0.0412 0.2435
Onchocerca volvulus Cathepsin L homolog 0.0664 0.1831 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.128 0.3559 1
Giardia lamblia Encystation-specific protease 0.0158 0.0412 0.2435
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.01 0.1346
Brugia malayi AMP-binding enzyme family protein 0.0047 0.01 0.0228
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.002 0.002
Brugia malayi beta-lactamase 0.0035 0.0066 0.0152
Entamoeba histolytica cysteine protease, putative 0.0158 0.0412 0.2218
Brugia malayi MH2 domain containing protein 0.0134 0.0345 0.0793
Echinococcus multilocularis short transient receptor potential channel 6 0.0064 0.0147 0.0147
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0491 0.1128
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0664 0.1831 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1562 0.435 1
Loa Loa (eye worm) cysteine protease 0.0664 0.1831 0.4208
Loa Loa (eye worm) inositol-1 0.0043 0.009 0.0206
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0047 0.0112
Onchocerca volvulus Cathepsin L homolog 0.0158 0.0412 0.2218
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0108 0.0271 0.0624
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0061 0.0817
Giardia lamblia Cathepsin B precursor 0.0592 0.163 1
Onchocerca volvulus 0.0035 0.0066 0.0325
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0066 0.0822
Echinococcus multilocularis lamin 0.0092 0.0227 0.0227
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0066 0.089
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.0491 0.1128
Schistosoma mansoni hypothetical protein 0.0108 0.0271 0.0624
Schistosoma mansoni ap endonuclease 0.0018 0.002 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0664 0.1831 1
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.0007 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.047 0.2564
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0041 0.0083 0.0214
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.01 0.1282
Trypanosoma brucei cysteine peptidase C (CPC) 0.0592 0.163 0.4568
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0066 0.089
Loa Loa (eye worm) hypothetical protein 0.0158 0.0412 0.0945
Onchocerca volvulus 0.0028 0.0047 0.0216
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0007 0.0035
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1562 0.435 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0664 0.1831 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0067 0.0823
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.002 0.0104
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.002 0.0069
Schistosoma mansoni aldehyde dehydrogenase 0.0071 0.0169 0.0388
Giardia lamblia Cathepsin L precursor 0.0158 0.0412 0.2435
Loa Loa (eye worm) hypothetical protein 0.0108 0.0271 0.0622
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0044 0.0093 0.1394
Schistosoma mansoni cpg binding protein 0.0028 0.0047 0.0107
Trypanosoma cruzi cysteine peptidase, putative 0.0363 0.0987 0.2256
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MF, Family M17 0.0041 0.0083 0.0214
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0205 0.0543 0.1233
Loa Loa (eye worm) hypothetical protein 0.0664 0.1831 0.4208
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0038 0.0172
Toxoplasma gondii ABC1 family protein 0.0035 0.0066 0.0325
Brugia malayi Bromodomain containing protein 0.0039 0.0078 0.0178
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0363 0.0987 0.2256
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.01 0.1282
Trypanosoma brucei ISWI complex protein 0.0014 0.0009 0.0004
Loa Loa (eye worm) hypothetical protein 0.0205 0.0544 0.1249
Toxoplasma gondii isocitrate dehydrogenase 0.003 0.0052 0.0248
Toxoplasma gondii aldehyde dehydrogenase 0.0071 0.0169 0.0887
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0555 0.1524 0.8323
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0038 0.0172
Loa Loa (eye worm) hypothetical protein 0.0036 0.0069 0.0157
Loa Loa (eye worm) acetyltransferase 0.0133 0.0341 0.0782
Schistosoma mansoni zinc finger protein 0.0023 0.0033 0.0076
Trypanosoma cruzi ISWI complex protein 0.0014 0.0009 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0158 0.0412 0.2246
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0158 0.0412 0.0946
Echinococcus multilocularis leucyl aminopeptidase 0.0041 0.0083 0.0083
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.128 0.3559 1
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0158 0.0412 0.2218
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0083 0.019
Loa Loa (eye worm) hypothetical protein 0.0047 0.01 0.0227
Schistosoma mansoni cathepsin C 0.0158 0.0412 0.0946
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0001 0.0002
Onchocerca volvulus 0.0664 0.1831 1
Brugia malayi Cyclic-nucleotide gated cation channel 0.0011 0.0001 0.0001
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0045 0.0095 0.0095
Plasmodium falciparum histone acetyltransferase GCN5 0.0035 0.0067 0.033
Schistosoma mansoni inositol monophosphatase 0.0043 0.009 0.0208
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0047 0.0112
Mycobacterium ulcerans hypothetical protein 0.0047 0.01 0.1282
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.0412 0.2246
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.009 0.0235
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0041 0.0083 0.0175
Plasmodium falciparum serine repeat antigen 3 0.0158 0.0412 0.2218
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0158 0.0412 0.2218
Echinococcus granulosus leucine aminopeptidase protein 0.0205 0.0543 0.1247
Brugia malayi Isocitrate dehydrogenase 0.003 0.0052 0.012
Entamoeba histolytica cysteine proteinase 2 0.0363 0.0987 0.5373
Entamoeba histolytica hypothetical protein 0.0124 0.0316 0.1693
Echinococcus granulosus TRP transient receptor potential channel 0.0037 0.0073 0.0167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0664 0.1831 1
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.0007 0.0074
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0047 0.0106
Trypanosoma cruzi cysteine proteinase, putative 0.0363 0.0987 0.2256
Onchocerca volvulus 0.0158 0.0412 0.2218
Entamoeba histolytica cysteine proteinase, putative 0.0664 0.1831 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0664 0.1831 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0169 0.2242
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0007 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.0412 0.2246
Echinococcus granulosus survival motor neuron protein 1 0.1316 0.3658 0.841
Loa Loa (eye worm) hypothetical protein 0.0035 0.0067 0.0151
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.009 0.049
Loa Loa (eye worm) hypothetical protein 0.0043 0.0088 0.0202
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0071 0.0169 0.0388
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0158 0.0412 0.2246
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0011 0.0001 0.0002
Echinococcus granulosus cathepsin l1 0.0459 0.1256 0.2886
Plasmodium vivax serine-repeat antigen (SERA) 0.0158 0.0412 0.2218
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0067 0.0326
Brugia malayi cathepsin L-like cysteine proteinase 0.0158 0.0412 0.0946
Loa Loa (eye worm) hypothetical protein 0.0066 0.0154 0.0351
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0007 0.0015
Entamoeba histolytica cysteine protease, putative 0.0363 0.0987 0.5373
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0083 0.019
Brugia malayi beta-lactamase family protein 0.0035 0.0066 0.0152
Trypanosoma cruzi cysteine peptidase, putative 0.128 0.3559 0.8179
Trichomonas vaginalis esterase, putative 0.0035 0.0066 0.0359
Brugia malayi PHD-finger family protein 0.0028 0.0047 0.0108
Schistosoma mansoni ferritin 0.0044 0.0093 0.0213
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0012 0.0027
Leishmania major hypothetical protein, conserved 0.0025 0.0038 0.0088
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.002 0.0029
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0079 0.0428
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0444 0.2424
Schistosoma mansoni ap endonuclease 0.0018 0.002 0.0045
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.0106 0.0244
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0043 0.009 0.1354
Echinococcus multilocularis zinc finger protein 0.0023 0.0033 0.0033
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0205 0.0543 0.7423
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0032 0.0171
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0001 0.0002
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0288 0.0777 0.1773
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0067 0.0326
Brugia malayi RNA, U transporter 1 0.0079 0.0191 0.0438
Giardia lamblia Cathepsin L precursor 0.0158 0.0412 0.2435
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0158 0.0412 0.2435
Giardia lamblia Cathepsin L precursor 0.0158 0.0412 0.2435
Schistosoma mansoni voltage-gated potassium channel 0.0049 0.0106 0.0244
Entamoeba histolytica cysteine protease, putative 0.0363 0.0987 0.5373
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0134 0.0696
Loa Loa (eye worm) hypothetical protein 0.0037 0.0073 0.0165
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0664 0.1831 1
Echinococcus granulosus transient receptor potential gamma protein 0.0095 0.0235 0.054
Toxoplasma gondii preprocathepsin c precursor, putative 0.0158 0.0412 0.2218
Brugia malayi cytoplasmic intermediate filament protein 0.0049 0.0107 0.0245
Schistosoma mansoni importin beta-1 0.0028 0.0047 0.0108
Schistosoma mansoni ferritin light chain 0.0044 0.0093 0.0213
Echinococcus granulosus ferritin 0.0044 0.0093 0.0213
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0066 0.0151
Loa Loa (eye worm) hypothetical protein 0.0047 0.01 0.0227
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0136 0.0351 0.0792
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0158 0.0412 0.0946
Schistosoma mansoni hypothetical protein 0.0019 0.0023 0.0052
Giardia lamblia Cathepsin B precursor 0.0592 0.163 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0044 0.0092 0.0211
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0108 0.0271 0.0271
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0103 0.0237
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0015 0.0012 0.0026
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0033 0.0063 0.0063
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.01 0.026
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0158 0.0412 0.2246
Echinococcus granulosus cpg binding protein 0.0031 0.0056 0.0129
Plasmodium vivax SET domain protein, putative 0.0028 0.0047 0.0219
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0012 0.0027
Trypanosoma brucei aminopeptidase, putative 0.0041 0.0083 0.0214
Loa Loa (eye worm) hypothetical protein 0.0043 0.0088 0.0202
Echinococcus granulosus importin subunit beta 1 0.0028 0.0047 0.0108
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0066 0.089
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0066 0.0153
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0047 0.0105
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.01 0.1282
Brugia malayi cathepsin L-like precursor 0.0459 0.1256 0.2886
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0158 0.0412 0.2218
Loa Loa (eye worm) hypothetical protein 0.0233 0.0623 0.143
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0044 0.0093 0.0093
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0032 0.0171
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0007 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0555 0.1524 0.8323
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0363 0.0987 0.2759
Brugia malayi AMP-binding enzyme family protein 0.0047 0.01 0.0228
Brugia malayi Bromodomain containing protein 0.0075 0.0178 0.0409
Brugia malayi hypothetical protein 0.0124 0.0316 0.0726
Plasmodium vivax importin-beta 2, putative 0.0028 0.0047 0.0217
Onchocerca volvulus Glucosylceramidase homolog 0.017 0.0444 0.2397
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0007 0.0016
Giardia lamblia Cathepsin B precursor 0.0158 0.0412 0.2435
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1562 0.435 1
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0444 0.2424
Echinococcus multilocularis lamin dm0 0.0092 0.0227 0.0227
Echinococcus multilocularis cathepsin b 0.1562 0.435 0.435
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0032 0.0171
Giardia lamblia Cathepsin B precursor 0.0158 0.0412 0.2435
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0205 0.0543 1
Schistosoma mansoni hypothetical protein 0.0124 0.0316 0.0726
Schistosoma mansoni hypothetical protein 0.0014 0.0009 0.002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0158 0.0412 0.2246
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0158 0.0412 0.0946
Schistosoma mansoni ferritin 0.0044 0.0093 0.0213
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0205 0.0543 0.1507
Plasmodium vivax vivapain-2 0.0664 0.1831 1
Entamoeba histolytica cysteine proteinase, putative 0.0363 0.0987 0.5373
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0039 0.0078 0.0978
Trichomonas vaginalis glucosylceramidase, putative 0.0258 0.0694 0.3786
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17 0.0041 0.0083 0.0175
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.01 0.1282
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.009 0.1155
Loa Loa (eye worm) hypothetical protein 0.0341 0.0925 0.2126
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.01 0.1282
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0158 0.0412 0.2246
Loa Loa (eye worm) fibroinase 0.0664 0.1831 0.4208
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0138 0.0318
Giardia lamblia Cathepsin B precursor 0.0592 0.163 1
Entamoeba histolytica cysteine protease, putative 0.0363 0.0987 0.5373
Brugia malayi Calcitonin receptor-like protein seb-1 0.0341 0.0925 0.2127
Plasmodium vivax vivapain-3 0.0363 0.0987 0.5373
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0664 0.1831 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.128 0.3559 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0664 0.1831 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0007 0.0074
Brugia malayi Latrophilin receptor protein 2 0.0108 0.0271 0.0623
Loa Loa (eye worm) hypothetical protein 0.1562 0.435 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0047 0.0108
Echinococcus granulosus cathepsin L 0.0363 0.0987 0.2269
Loa Loa (eye worm) MH2 domain-containing protein 0.0134 0.0345 0.0792
Schistosoma mansoni transient receptor potential channel 0.0064 0.0147 0.0339
Schistosoma mansoni transcription factor LCR-F1 0.0124 0.0316 0.0726

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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