Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0012 | 0.0054 | 0.0044 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0496 | 0.2735 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0012 | 0.0054 | 0.0044 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0058 | 0.1127 | 0.1119 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1137 | 0.736 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0208 | 0.0208 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0012 | 0.0054 | 0.0347 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0012 | 0.0054 | 0.0347 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.001 | 0.0009 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0054 | 0.0347 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.001 | 0.0009 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0012 | 0.0054 | 0.0053 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0204 | 0.0195 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0058 | 0.1137 | 0.6628 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0012 | 0.0054 | 0.0347 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0707 | 0.0699 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.3211 | 0.3205 |
Echinococcus multilocularis | tumor protein p63 | 0.0395 | 0.8993 | 0.8993 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0159 | 0.3487 | 0.3487 |
Schistosoma mansoni | thyroid hormone receptor | 0.0159 | 0.3487 | 0.3481 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.0054 | 0.0054 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0208 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0054 | 0.0347 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0054 | 0.0347 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.0054 | 0.0054 |
Onchocerca volvulus | 0.0058 | 0.1127 | 1 | |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0012 | 0.0054 | 0.0053 |
Trypanosoma cruzi | ISWI complex protein | 0.0016 | 0.016 | 0.5 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0204 | 0.0195 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0012 | 0.0054 | 0.0053 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0208 | 0.0208 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.001 | 0.0009 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0082 | 0.1693 | 1 |
Brugia malayi | steroid hormone receptor | 0.0012 | 0.0054 | 0.0053 |
Leishmania major | hypothetical protein, conserved | 0.0016 | 0.016 | 0.5 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0208 | 0.0208 |
Treponema pallidum | bacterioferrin (TpF1) | 0.001 | 0.0009 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0737 | 0.4768 |
Onchocerca volvulus | 0.0031 | 0.0496 | 0.412 | |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.1137 | 0.736 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.0054 | 0.0054 |
Trypanosoma brucei | ISWI complex protein | 0.0016 | 0.016 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0208 | 0.0208 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.0707 | 0.4019 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0012 | 0.0054 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0208 | 0.0199 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0208 | 0.0199 |
Echinococcus multilocularis | zinc finger protein | 0.0023 | 0.0308 | 0.0308 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0294 | 0.0285 |
Echinococcus multilocularis | expressed protein | 0.001 | 0.0009 | 0.0009 |
Brugia malayi | PHD-finger family protein | 0.0028 | 0.0441 | 0.2406 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.0054 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.016 | 0.0151 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0012 | 0.0054 | 0.0044 |
Schistosoma mansoni | bromodomain containing protein | 0.007 | 0.14 | 0.1392 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.0219 | 0.142 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0496 | 0.0487 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.022 | 0.1422 |
Schistosoma mansoni | thyroid hormone receptor | 0.0159 | 0.3487 | 0.3481 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0496 | 0.3207 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.0054 | 0.0054 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0019 | 0.022 | 0.0211 |
Echinococcus granulosus | expressed protein | 0.001 | 0.0009 | 0.0009 |
Echinococcus granulosus | tumor protein p63 | 0.0395 | 0.8993 | 0.8993 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0012 | 0.0054 | 0.0053 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.0735 | 0.4187 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0147 | 0.3211 | 0.3211 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0676 | 0.0676 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0208 | 0.0208 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0054 | 0.0347 |
Echinococcus multilocularis | ferritin | 0.001 | 0.0009 | 0.0009 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0065 | 0.13 | 0.1292 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0018 | 0.0204 | 0.0204 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0012 | 0.0054 | 0.0044 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0066 | 0.1311 | 0.1311 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0012 | 0.0054 | 0.0044 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0012 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1545 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0438 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.0054 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0208 | 0.0199 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0012 | 0.0054 | 0.0044 |
Echinococcus granulosus | cpg binding protein | 0.0035 | 0.0584 | 0.0584 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.001 | 0.0009 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.0054 | 0.0054 |
Schistosoma mansoni | zinc finger protein | 0.0023 | 0.0308 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1127 | 0.7291 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0208 | 0.099 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.1197 | 0.5 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0208 | 0.099 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.0054 | 0.0054 |
Brugia malayi | ecdysteroid receptor | 0.0012 | 0.0054 | 0.0053 |
Brugia malayi | nuclear receptor NHR-88 | 0.0012 | 0.0054 | 0.0053 |
Brugia malayi | nuclear hormone receptor | 0.0012 | 0.0054 | 0.0053 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.0054 | 0.0053 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.0054 | 0.0053 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0012 | 0.0054 | 0.0044 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.0054 | 0.0054 |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.001 | 0.0009 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0012 | 0.0054 | 0.0347 |
Schistosoma mansoni | coup transcription factor | 0.0012 | 0.0054 | 0.0044 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0012 | 0.0054 | 0.0054 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0147 | 0.3211 | 0.3211 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0019 | 0.022 | 0.022 |
Trichomonas vaginalis | ferritin, putative | 0.001 | 0.0009 | 0.5 |
Echinococcus multilocularis | cpg binding protein | 0.0035 | 0.0584 | 0.0584 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0012 | 0.0054 | 0.0347 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.0054 | 0.0054 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0019 | 0.022 | 0.0211 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0012 | 0.0054 | 0.0347 |
Echinococcus granulosus | zinc finger protein | 0.0023 | 0.0308 | 0.0308 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0676 | 0.0676 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0012 | 0.0054 | 0.0053 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0012 | 0.0054 | 0.0347 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0012 | 0.0054 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0054 | 0.0347 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0012 | 0.0054 | 0.0054 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0066 | 0.1311 | 0.1311 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0012 | 0.0054 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0208 | 0.1347 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0054 | 0.0347 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.001 | 0.0009 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0012 | 0.0054 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0054 | 0.0347 |
Schistosoma mansoni | nuclear hormone receptor | 0.0012 | 0.0054 | 0.0044 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0584 | 0.0576 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0019 | 0.022 | 0.022 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0208 | 0.1347 |
Echinococcus granulosus | FTZ F1 alpha | 0.0012 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0885 | 0.5725 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0012 | 0.0054 | 0.0054 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0012 | 0.0054 | 0.0044 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 0.1137 | 0.6628 |
Echinococcus granulosus | ferritin | 0.001 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0294 | 0.19 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0584 | 0.0576 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0012 | 0.0054 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0707 | 0.4577 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0012 | 0.0054 | 0.0347 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0208 | 0.0208 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0026 | 0.0382 | 0.0373 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.0054 | 0.0054 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.0054 | 0.0053 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.0054 | 0.0054 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0438 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.0054 | 0.0053 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0018 | 0.0204 | 0.0204 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.0054 | 0.0053 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0012 | 0.0054 | 0.0054 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0012 | 0.0054 | 0.0054 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0026 | 0.0382 | 0.0382 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0026 | 0.0382 | 0.0382 |
Schistosoma mansoni | zinc finger protein | 0.0016 | 0.016 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0796 | 0.5151 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0054 | 0.0347 |
Trypanosoma cruzi | ISWI complex protein | 0.0016 | 0.016 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.