Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.027 | 0.0185 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.0161 | 0.0076 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.1613 | 0.1884 |
Echinococcus granulosus | tar DNA binding protein | 0.0197 | 0.3501 | 0.3495 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0009 | 0.0016 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0339 | 0.033 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0246 | 0.4414 | 0.7484 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.027 | 0.0261 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0019 | 0.0118 | 0.0139 |
Echinococcus granulosus | RUN | 0.0021 | 0.0161 | 0.0152 |
Schistosoma mansoni | polycystin 1-related | 0.0021 | 0.0161 | 0.0076 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.0943 | 0.1599 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0049 | 0.0691 | 0.0682 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0086 | 0.0077 |
Onchocerca volvulus | 0.0029 | 0.0308 | 0.0255 | |
Schistosoma mansoni | hypothetical protein | 0.0289 | 0.5239 | 0.5198 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0308 | 0.0522 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.003 | 0.0336 | 0.0327 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0048 | 0.0666 | 0.088 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0098 | 0.1613 | 0.2531 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.031 | 0.5631 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0666 | 0.1129 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0187 | 0.3314 | 0.3308 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0048 | 0.0666 | 0.1129 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0021 | 0.0161 | 0.3009 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.0793 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0078 | 0.1249 | 0.1173 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0259 | 0.1129 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.027 | 0.04 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0691 | 0.061 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.155 | 0.1476 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.155 | 0.1476 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.031 | 0.5631 | 1 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0084 | 0.0082 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0339 | 0.0255 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.1613 | 0.1884 |
Brugia malayi | Doublecortin family protein | 0.0021 | 0.0161 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0791 | 0.1341 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0094 | 0.155 | 0.2627 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0691 | 0.1171 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0049 | 0.0691 | 0.0682 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.031 | 0.5631 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0259 | 0.1129 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0038 | 0.0487 | 0.0478 |
Onchocerca volvulus | Alhambra homolog | 0.003 | 0.0336 | 0.0304 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0161 | 0.0274 |
Loa Loa (eye worm) | hypothetical protein | 0.0324 | 0.5898 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0408 | 0.7486 | 0.7464 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0408 | 0.7486 | 0.7484 |
Onchocerca volvulus | 0.0324 | 0.5898 | 1 | |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0021 | 0.0161 | 0.0152 |
Loa Loa (eye worm) | doublecortin family protein | 0.0021 | 0.0161 | 0.0274 |
Brugia malayi | jmjC domain containing protein | 0.0038 | 0.0487 | 0.0769 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0094 | 0.155 | 0.1542 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.0791 | 0.0711 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.027 | 0.04 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.027 | 0.0458 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.003 | 0.0336 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.269 | 0.456 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0036 | 0.0061 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0086 | 0.0077 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.027 | 0.0458 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.031 | 0.5631 | 1 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0021 | 0.0161 | 0.0152 |
Onchocerca volvulus | 0.0027 | 0.027 | 0.019 | |
Brugia malayi | isocitrate dehydrogenase | 0.0017 | 0.0086 | 0.0086 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0106 | 0.1764 | 0.2949 |
Brugia malayi | TAR-binding protein | 0.0197 | 0.3501 | 0.5911 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.155 | 0.1476 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.031 | 0.5631 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.0666 | 0.0585 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0098 | 0.1613 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0259 | 0.1129 |
Schistosoma mansoni | hypothetical protein | 0.0106 | 0.1764 | 0.1693 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0094 | 0.155 | 0.1542 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0098 | 0.1613 | 1 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0059 | 0.0874 | 0.0865 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0259 | 0.038 |
Echinococcus multilocularis | musashi | 0.0027 | 0.027 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0161 | 0.0274 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0098 | 0.1613 | 0.154 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0261 | 0.0443 |
Loa Loa (eye worm) | RNA binding protein | 0.0197 | 0.3501 | 0.5936 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0154 | 0.269 | 0.456 |
Trypanosoma brucei | polo-like protein kinase | 0.0098 | 0.1613 | 1 |
Echinococcus granulosus | jumonji domain containing protein | 0.0042 | 0.0559 | 0.0551 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.003 | 0.0336 | 0.0327 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.031 | 0.5631 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.031 | 0.5631 | 0.5 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0048 | 0.0666 | 0.0658 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0048 | 0.0666 | 0.0585 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.031 | 0.5631 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.031 | 0.5631 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0197 | 0.3501 | 0.5936 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.0791 | 0.0782 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0336 | 0.0252 |
Schistosoma mansoni | hypothetical protein | 0.0541 | 1 | 1 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0059 | 0.0874 | 0.0865 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0098 | 0.1613 | 0.2735 |
Schistosoma mansoni | tar DNA-binding protein | 0.0197 | 0.3501 | 0.3444 |
Echinococcus granulosus | dnaJ subfamily B | 0.0408 | 0.7486 | 0.7484 |
Brugia malayi | jmjC domain containing protein | 0.0099 | 0.1633 | 0.2725 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0048 | 0.0666 | 0.0658 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0154 | 0.269 | 0.4527 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0187 | 0.3314 | 0.3308 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.1613 | 0.1884 |
Onchocerca volvulus | 0.0027 | 0.027 | 0.019 | |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0098 | 0.1613 | 0.1605 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0336 | 0.3533 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0308 | 0.0223 |
Echinococcus multilocularis | GPCR, family 2 | 0.0049 | 0.0691 | 0.0682 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0259 | 0.1129 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0049 | 0.0691 | 0.1117 |
Echinococcus granulosus | GPCR family 2 | 0.0049 | 0.0691 | 0.0682 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0048 | 0.0666 | 0.0658 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.0666 | 0.1075 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.0791 | 0.0782 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.0791 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0743 | 0.126 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.1613 | 0.1884 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.031 | 0.5631 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.027 | 0.0261 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.1613 | 0.1884 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0259 | 0.6907 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.031 | 0.5631 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0094 | 0.155 | 0.1542 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.0487 | 0.0404 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0021 | 0.0161 | 0.3009 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.0916 | 0.0836 |
Echinococcus multilocularis | geminin | 0.0541 | 1 | 1 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0151 | 0.2631 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.003 | 0.0336 | 0.0512 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0336 | 0.0512 |
Echinococcus multilocularis | tar DNA binding protein | 0.0197 | 0.3501 | 0.3495 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0049 | 0.0691 | 0.0682 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.027 | 0.0261 |
Plasmodium falciparum | phd finger protein, putative | 0.003 | 0.0336 | 1 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0339 | 0.033 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.0791 | 0.0782 |
Onchocerca volvulus | 0.0048 | 0.0666 | 0.088 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0197 | 0.3501 | 0.3444 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0086 | 0.0077 |
Schistosoma mansoni | loxhd1 | 0.0021 | 0.0161 | 0.0076 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0691 | 0.061 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.0791 | 0.1341 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.1764 | 0.2992 |
Plasmodium vivax | hypothetical protein, conserved | 0.003 | 0.0336 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.1613 | 0.1884 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0017 | 0.0086 | 0.0077 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.0161 | 0.0152 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0086 | 0.0077 |
Brugia malayi | RNA binding protein | 0.0197 | 0.3501 | 0.5911 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0161 | 0.0214 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.0161 | 0.0152 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0259 | 0.6907 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0308 | 0.0464 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.027 | 0.0458 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0048 | 0.0666 | 0.0585 |
Brugia malayi | hypothetical protein | 0.0324 | 0.5898 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.0487 | 0.0404 |
Schistosoma mansoni | lamin | 0.0027 | 0.027 | 0.0185 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0098 | 0.1613 | 1 |
Schistosoma mansoni | lamin | 0.0027 | 0.027 | 0.0185 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0099 | 0.1633 | 0.1626 |
Echinococcus multilocularis | peregrin | 0.003 | 0.0336 | 0.0327 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0197 | 0.3501 | 0.5936 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0336 | 0.3533 |
Schistosoma mansoni | tar DNA-binding protein | 0.0197 | 0.3501 | 0.3444 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0161 | 0.0076 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0042 | 0.0559 | 0.0551 |
Echinococcus granulosus | lamin | 0.0027 | 0.027 | 0.0261 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0339 | 0.0255 |
Brugia malayi | follicle stimulating hormone receptor | 0.0246 | 0.4414 | 0.7468 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0098 | 0.1613 | 0.1605 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0197 | 0.3501 | 0.5911 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0099 | 0.1633 | 0.1626 |
Schistosoma mansoni | tar DNA-binding protein | 0.0197 | 0.3501 | 0.3444 |
Schistosoma mansoni | kinase | 0.005 | 0.0705 | 0.0624 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.0161 | 0.0076 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0048 | 0.0666 | 0.0658 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.031 | 0.5631 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0021 | 0.0161 | 0.0076 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0017 | 0.0086 | 0.0146 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.0161 | 0.0152 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.0456 | 0.0447 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.0791 | 0.0782 |
Echinococcus multilocularis | lamin | 0.0027 | 0.027 | 0.0261 |
Brugia malayi | mbt repeat family protein | 0.0048 | 0.0666 | 0.1075 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0336 | 0.057 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0098 | 0.1613 | 0.1884 |
Loa Loa (eye worm) | PHD-finger family protein | 0.003 | 0.0336 | 0.057 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0259 | 0.6907 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0094 | 0.155 | 0.1542 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0094 | 0.155 | 0.2582 |
Echinococcus granulosus | peregrin | 0.003 | 0.0336 | 0.0327 |
Schistosoma mansoni | tar DNA-binding protein | 0.0197 | 0.3501 | 0.3444 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0049 | 0.0691 | 0.0682 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0154 | 0.269 | 0.4527 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0151 | 0.2631 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0691 | 0.061 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0161 | 0.0214 |
Schistosoma mansoni | lipoxygenase | 0.0059 | 0.0874 | 0.0794 |
Giardia lamblia | Kinase, PLK | 0.0098 | 0.1613 | 0.2412 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0691 | 0.061 |
Brugia malayi | Isocitrate dehydrogenase | 0.0017 | 0.0086 | 0.0086 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0259 | 0.244 |
Echinococcus multilocularis | RUN | 0.0021 | 0.0161 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0259 | 0.0439 |
Schistosoma mansoni | hypothetical protein | 0.0541 | 1 | 1 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.0161 | 0.0152 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0049 | 0.0691 | 0.1171 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0049 | 0.0691 | 0.1117 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0038 | 0.0487 | 0.0825 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0151 | 0.2631 | 1 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0098 | 0.1613 | 0.269 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0017 | 0.0086 | 0.0077 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.