Detailed information for compound 1165451

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 357.467 | Formula: C20H23NO3S
  • H donors: 0 H acceptors: 0 LogP: 3.31 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc2c(c1)Oc1c(C2SCCN2CCOCC2)cccc1
  • InChi: 1S/C20H23NO3S/c1-22-15-6-7-17-19(14-15)24-18-5-3-2-4-16(18)20(17)25-13-10-21-8-11-23-12-9-21/h2-7,14,20H,8-13H2,1H3
  • InChiKey: FEWZQQHIZAEXEV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major trypanothione reductase 0.0048 0.0825 1
Loa Loa (eye worm) RNA binding protein 0.0131 0.2664 0.4578
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0468 0.0805
Echinococcus multilocularis tar DNA binding protein 0.0131 0.2664 0.2662
Plasmodium vivax glutathione reductase, putative 0.0048 0.0825 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0468 0.0466
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0468 0.0805
Trichomonas vaginalis glutaminase, putative 0.0275 0.5815 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0468 0.0801
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0825 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0105 0.0176
Schistosoma mansoni transient receptor potential channel 0.0104 0.2056 0.1971
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0143 0.0864
Echinococcus granulosus short transient receptor potential channel 6 0.0068 0.1285 0.1283
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0143 0.0864
Leishmania major basic transcription factor 3a, putative 0.0037 0.06 0.6995
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0468 0.0367
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0105 0.0176
Loa Loa (eye worm) hypothetical protein 0.0031 0.0468 0.0801
Echinococcus multilocularis transcription factor btf3 0.0037 0.06 0.0598
Toxoplasma gondii thioredoxin reductase 0.0048 0.0825 0.6338
Schistosoma mansoni transcription factor btf3 0.0037 0.06 0.05
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0105 0.0102
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0468 0.0367
Loa Loa (eye worm) hypothetical protein 0.0015 0.0105 0.0176
Plasmodium vivax basic transcription factor 3b, putative 0.0037 0.06 0.6711
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0105 0.0102
Brugia malayi RNA recognition motif domain containing protein 0.0131 0.2664 0.4581
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0722 0.5382
Brugia malayi glutathione reductase 0.0048 0.0825 0.1418
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0105 0.0152
Loa Loa (eye worm) hypothetical protein 0.0031 0.0468 0.0801
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0143 0.014
Onchocerca volvulus 0.0033 0.0498 0.2358
Loa Loa (eye worm) acetyltransferase 0.0146 0.298 0.5123
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0144 0.0248
Loa Loa (eye worm) hypothetical protein 0.0015 0.0105 0.0176
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0579 0.0873
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0105 0.0152
Echinococcus multilocularis transient receptor potential ion channel A 0.01 0.198 0.1977
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0468 0.2189
Loa Loa (eye worm) hypothetical protein 0.0031 0.0468 0.0801
Brugia malayi conserved hypotetical protein 0.0015 0.0105 0.0181
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0105 0.0102
Brugia malayi nuclear hormone receptor 0.0015 0.0105 0.0181
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0143 0.5
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0468 0.0466
Loa Loa (eye worm) hypothetical protein 0.0017 0.0144 0.0243
Brugia malayi nuclear receptor NHR-67 0.0015 0.0105 0.0181
Onchocerca volvulus 0.0015 0.0105 0.0152
Brugia malayi glutaminase DH11.1 0.0275 0.5815 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0468 0.0367
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0579 0.0995
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.2162 0.8837
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0468 0.0466
Entamoeba histolytica hypothetical protein 0.0037 0.06 0.9239
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.2162 0.8837
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0105 0.0181
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.298 0.2905
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.2427 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0105 0.0176
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0468 0.0367
Brugia malayi Transient-receptor-potential like protein 0.0039 0.0627 0.1078
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0468 0.0367
Loa Loa (eye worm) hypothetical protein 0.0015 0.0105 0.0176
Echinococcus multilocularis short transient receptor potential channel 6 0.0068 0.1285 0.1283
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0143 0.0112
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0047 0.008
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0143 0.5
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0825 0.0822
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.06 0.6995
Mycobacterium ulcerans glutaminase 0.0275 0.5815 1
Toxoplasma gondii NAC domain-containing protein 0.0037 0.06 0.4254
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0143 0.0864
Schistosoma mansoni tar DNA-binding protein 0.0131 0.2664 0.2586
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0144 0.0141
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0722 0.1122
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0722 0.8491
Loa Loa (eye worm) hypothetical protein 0.0015 0.0105 0.0176
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0105 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0468 0.0805
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0722 0.1122
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0468 0.0805
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.289 0.2888
Schistosoma mansoni cpg binding protein 0.0033 0.0498 0.0397
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0105 0.0102
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0105 0.0102
Brugia malayi nuclear receptor RXR 0.0015 0.0105 0.0181
Plasmodium falciparum thioredoxin reductase 0.0048 0.0825 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.2056 0.3532
Schistosoma mansoni tar DNA-binding protein 0.0131 0.2664 0.2586
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.06 0.091
Plasmodium falciparum glutathione reductase 0.0048 0.0825 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0143 0.0245
Trypanosoma brucei glucosidase, putative 0.0036 0.0579 0.6708
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0579 0.6708
Brugia malayi Glycosyl hydrolases family 31 protein 0.0164 0.3377 0.5808
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.1303 0.121
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0143 0.0864
Brugia malayi nuclear receptor NHR-88 0.0015 0.0105 0.0181
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0143 0.0864
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0078 0.0134
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0143 0.0864
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0468 0.0805
Loa Loa (eye worm) DR-78 0.0015 0.0105 0.0176
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.2427 1
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0105 0.0102
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.1219 1
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0468 0.0466
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0468 0.0805
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0722 0.5382
Loa Loa (eye worm) hypothetical protein 0.0014 0.0078 0.0129
Schistosoma mansoni transient receptor potential channel 0.0068 0.1285 0.1193
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0468 0.0466
Loa Loa (eye worm) hypothetical protein 0.0015 0.0105 0.0176
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0143 0.0864
Loa Loa (eye worm) hypothetical protein 0.0015 0.0105 0.0176
Schistosoma mansoni hypothetical protein 0.0465 1 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0579 0.0873
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0143 0.0038
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0105 0.0181
Schistosoma mansoni alpha-glucosidase 0.0141 0.2876 0.2801
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0468 0.0805
Brugia malayi tailless protein 0.0015 0.0105 0.0181
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0143 0.0864
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0468 0.0805
Loa Loa (eye worm) hypothetical protein 0.0035 0.0551 0.0943
Brugia malayi nuclear receptor NHR-88 0.0031 0.0468 0.0805
Onchocerca volvulus 0.0031 0.0468 0.2189
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0039 0.0627 0.0624
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0143 0.0864
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0468 0.0466
Loa Loa (eye worm) hypothetical protein 0.0015 0.0105 0.0176
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0105 0.0176
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.2162 0.8837
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0105 0.0181
Loa Loa (eye worm) TAR-binding protein 0.0131 0.2664 0.4578
Brugia malayi nuclear hormone receptor 0.0031 0.0468 0.0805
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0579 0.0873
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0468 0.2189
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.2162 0.8837
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0468 0.0805
Echinococcus granulosus short transient receptor potential channel 6 0.0068 0.1285 0.1283
Loa Loa (eye worm) hypothetical protein 0.0017 0.0144 0.0243
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0468 0.0367
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0143 0.0864
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0143 0.5
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0468 0.0466
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0468 0.0805
Brugia malayi beta-NAC-like protein 0.0037 0.06 0.1032
Echinococcus granulosus tar DNA binding protein 0.0131 0.2664 0.2662
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0468 0.0801
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0643 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0105 0.0176
Treponema pallidum NADH oxidase 0.0016 0.0143 0.5
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0825 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0468 0.0466
Brugia malayi hypothetical protein 0.0015 0.0105 0.0181
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0579 0.0576
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.2427 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0468 0.0805
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0468 0.0805
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0143 0.0864
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0468 0.2189
Loa Loa (eye worm) glutaminase 2 0.0275 0.5815 1
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0825 0.1414
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0468 0.0801
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0468 0.0466
Loa Loa (eye worm) hypothetical protein 0.0015 0.0105 0.0176
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0468 0.0801
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0825 0.2985
Echinococcus granulosus transient receptor potential ion channel A 0.01 0.198 0.1977
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0468 0.0801
Brugia malayi Thioredoxin reductase 0.0048 0.0825 0.1418
Echinococcus multilocularis cpg binding protein 0.0035 0.0539 0.0537
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.2427 1
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0468 0.0801
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.3377 0.3375
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0468 0.0466
Schistosoma mansoni transient receptor potential channel 0.0068 0.1285 0.1193
Schistosoma mansoni tar DNA-binding protein 0.0131 0.2664 0.2586
Trypanosoma brucei transcription factor BTF3, putative 0.0037 0.06 0.6995
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0579 0.4055
Loa Loa (eye worm) hypothetical protein 0.0039 0.0627 0.1074
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.2162 0.8837
Schistosoma mansoni alpha glucosidase 0.0036 0.0579 0.0479
Echinococcus granulosus transient receptor potential gamma protein 0.0104 0.2056 0.2053
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0105 0.0102
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0143 0.0864
Onchocerca volvulus 0.0015 0.0105 0.0152
Loa Loa (eye worm) hypothetical protein 0.0015 0.0105 0.0176
Loa Loa (eye worm) hypothetical protein 0.0031 0.0468 0.0801
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0468 0.0466
Brugia malayi hypothetical protein 0.0015 0.0105 0.0181
Echinococcus granulosus TRP transient receptor potential channel 0.0039 0.0627 0.0624
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0144 0.0039
Loa Loa (eye worm) hypothetical protein 0.0017 0.0144 0.0243
Loa Loa (eye worm) ICD-1 protein 0.0037 0.06 0.1028
Brugia malayi nuclear receptor RXR 0.0017 0.0144 0.0248
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0144 0.0039
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0468 0.0466
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0468 0.0367
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0143 0.0864
Schistosoma mansoni transient receptor potential channel 4 0.0104 0.2056 0.1971
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0498 0.0853
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0579 0.6708
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0579 0.886
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0579 0.886
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0468 0.0805
Brugia malayi ecdysteroid receptor 0.0031 0.0468 0.0805
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0105 0.0181
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0468 0.0805
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0468 0.0466
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0722 0.0719
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.06 0.6995
Schistosoma mansoni alpha-glucosidase 0.0141 0.2876 0.2801
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0105 0.0102
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0105 0.0102
Brugia malayi TAR-binding protein 0.0131 0.2664 0.4581
Onchocerca volvulus 0.0095 0.1861 1
Mycobacterium tuberculosis Probable reductase 0.0108 0.2162 0.8837
Schistosoma mansoni cpg binding protein 0.0035 0.0539 0.0439
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0825 0.0822
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0579 0.0576
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0468 0.0466
Schistosoma mansoni tar DNA-binding protein 0.0131 0.2664 0.2586
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0579 0.0873
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0579 0.0873
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0143 0.0864
Loa Loa (eye worm) hypothetical protein 0.0065 0.121 0.2076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0468 0.0801
Loa Loa (eye worm) hypothetical protein 0.0031 0.0468 0.0801
Loa Loa (eye worm) hypothetical protein 0.0015 0.0105 0.0176
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0468 0.0367
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0144 0.0248
Loa Loa (eye worm) glutathione reductase 0.0048 0.0825 0.1414
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.298 0.5125
Echinococcus granulosus lysosomal alpha glucosidase 0.0164 0.3377 0.3375
Brugia malayi ecdysone receptor 0.0015 0.0105 0.0181
Loa Loa (eye worm) hypothetical protein 0.0017 0.0144 0.0243
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0144 0.0141
Loa Loa (eye worm) hypothetical protein 0.0031 0.0468 0.0801
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0579 0.0991
Brugia malayi steroid hormone receptor 0.0031 0.0468 0.0805
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0579 0.6708
Echinococcus multilocularis transient receptor potential gamma protein 0.0104 0.2056 0.2053
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0105 0.0102
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0143 0.0864
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0143 0.0864
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0643 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0579 0.0873
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0468 0.0367
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0468 0.0367
Schistosoma mansoni glutaminase 0.0275 0.5815 0.577
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0468 0.0466
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0468 0.0466
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0105 0.0102
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0143 0.0112
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0468 0.0801
Schistosoma mansoni tar DNA-binding protein 0.0131 0.2664 0.2586
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.06 0.091
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0143 0.0864
Loa Loa (eye worm) hypothetical protein 0.0031 0.0468 0.0801
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0468 0.0805
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0105 0.0181
Schistosoma mansoni coup transcription factor 0.0031 0.0468 0.0367
Echinococcus granulosus transcription factor btf3 0.0037 0.06 0.0598
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0579 0.0873
Loa Loa (eye worm) glutaminase 0.0275 0.5815 1
Echinococcus granulosus cpg binding protein 0.0035 0.0539 0.0537
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0468 0.0805
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.06 0.091
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0579 0.0873
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0047 0.008
Echinococcus multilocularis short transient receptor potential channel 6 0.0068 0.1285 0.1283
Trypanosoma brucei trypanothione reductase 0.0048 0.0825 1
Schistosoma mansoni cpg binding protein 0.0035 0.0539 0.0439
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.298 0.2978
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.3377 0.3375
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0105 0.0102
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0643 0.7342
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0131 0.2664 0.4578
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0468 0.0466
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0164 0.3377 0.5806
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0144 0.0243
Brugia malayi hypothetical protein 0.0017 0.0144 0.0248
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0468 0.0367
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0468 0.0801
Plasmodium falciparum basic transcription factor 3b, putative 0.0037 0.06 0.6711
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0143 0.014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0144 0.0243
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0468 0.0466
Brugia malayi hypothetical protein 0.0017 0.0144 0.0248
Brugia malayi CXXC zinc finger family protein 0.0033 0.0498 0.0857
Brugia malayi RNA binding protein 0.0131 0.2664 0.4581
Loa Loa (eye worm) hypothetical protein 0.0015 0.0105 0.0176
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0468 0.0367
Echinococcus multilocularis dnaJ subfamily B 0.0465 1 1
Entamoeba histolytica transcription factor BTF3, putative 0.0037 0.06 0.9239
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0579 0.0873

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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