Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.044 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.044 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.044 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.044 | 0.0022 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.3727 | 0.3453 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.044 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3727 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.044 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.3727 | 0.3453 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.2419 | 0.2088 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0419 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.3727 | 0.3453 |
Echinococcus multilocularis | muscleblind protein | 0.0149 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.044 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.044 | 1 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.044 | 0.0022 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.044 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.044 | 0.0065 |
Echinococcus granulosus | muscleblind protein | 0.0149 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.2419 | 0.2088 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0419 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3727 | 1 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.044 | 0.0022 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.044 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.044 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2419 | 0.6048 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3727 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0419 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.044 | 0.0022 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2419 | 0.6048 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0419 | 0.9513 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.044 | 0.0022 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.044 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.2419 | 0.2088 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.044 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.044 | 1 |
Brugia malayi | RNA binding protein | 0.0064 | 0.3727 | 0.3453 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0419 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.044 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.044 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.3727 | 0.3453 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.3727 | 0.3453 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3727 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0149 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3727 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2419 | 0.6048 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.044 | 0.0022 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.044 | 0.0022 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.2419 | 0.2088 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0419 | 0.5 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.044 | 0.0022 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.2419 | 0.2088 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.044 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.044 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.044 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 1 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.044 | 0.0022 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.3727 | 0.3453 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.044 | 0.0065 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.044 | 0.0065 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.2419 | 0.2088 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.3727 | 0.3453 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.