Detailed information for compound 1166550

Basic information

Technical information
  • TDR Targets ID: 1166550
  • Name: 7-(3-aminopyrrolidin-1-yl)-6-chloro-4-oxo-1-( 1,3-thiazol-2-yl)-1,8-naphthyridine-3-carboxy lic acid
  • MW: 391.832 | Formula: C16H14ClN5O3S
  • H donors: 2 H acceptors: 5 LogP: 0.23 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC1CCN(C1)c1nc2c(cc1Cl)c(=O)c(cn2c1nccs1)C(=O)O
  • InChi: 1S/C16H14ClN5O3S/c17-11-5-9-12(23)10(15(24)25)7-22(16-19-2-4-26-16)13(9)20-14(11)21-3-1-8(18)6-21/h2,4-5,7-8H,1,3,6,18H2,(H,24,25)
  • InChiKey: NGCCKXFSVAZOQN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 7-(3-aminopyrrolidin-1-yl)-6-chloro-4-oxo-1-thiazol-2-yl-1,8-naphthyridine-3-carboxylic acid
  • 7-(3-amino-1-pyrrolidinyl)-6-chloro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
  • 7-(3-aminopyrrolidin-1-yl)-6-chloro-4-keto-1-thiazol-2-yl-1,8-naphthyridine-3-carboxylic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis adenylate cyclase, putative 0.0063 0.0193 0.0533
Brugia malayi cathepsin Z-like cysteine proteinase 0.0179 0.0598 0.1467
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.0193 0.0473
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.011
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0012 0.0014 0.0033
Mycobacterium ulcerans transmembrane transport protein 0.0088 0.028 0.2769
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0018 0.0042
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Mycobacterium ulcerans hypothetical protein 0.015 0.0494 0.5169
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0017 0.0033 0.006
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0088 0.028 0.0686
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.015 0.0494 0.1212
Brugia malayi jmjC domain containing protein 0.0065 0.02 0.0491
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0104 0.0218
Schistosoma mansoni elf1 0.0011 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0179 0.0598 0.1738
Onchocerca volvulus 0.0835 0.2887 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0193 0.0472
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0042
Schistosoma mansoni ap endonuclease 0.0038 0.0104 0.0103
Loa Loa (eye worm) beta-lactamase 0.015 0.0494 0.1212
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.023 0.0776 0.0776
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0325 0.0926
Echinococcus granulosus tissue type plasminogen activator 0.0026 0.0064 0.0155
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0179 0.0598 0.1738
Loa Loa (eye worm) hypothetical protein 0.015 0.0494 0.1212
Trypanosoma cruzi polo-like protein kinase, putative 0.0204 0.0685 0.1649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0835 0.2887 1
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0089 0.0282 0.0692
Trichomonas vaginalis esterase, putative 0.015 0.0494 0.143
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0044 0.0126 0.0307
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Brugia malayi aspartic protease BmAsp-1, identical 0.023 0.0776 0.1906
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0021 0.0046 0.0112
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0031 0.0075
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0184 0.0451
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0445 0.1526 0.526
Trichomonas vaginalis adenylate cyclase, putative 0.0063 0.0193 0.0533
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0179 0.0598 0.1738
Toxoplasma gondii aspartyl protease ASP1 0.0975 0.3373 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0835 0.2887 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0104 0.0218
Brugia malayi RNA recognition motif domain containing protein 0.0031 0.008 0.0197
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0179 0.0598 0.3463
Echinococcus granulosus cathepsin b 0.1175 0.4074 1
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0031 0.0031
Entamoeba histolytica cysteine protease, putative 0.0445 0.1526 0.5263
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0179 0.0598 0.1745
Entamoeba histolytica cysteine protease, putative 0.0445 0.1526 0.5263
Onchocerca volvulus Cathepsin L homolog 0.0835 0.2887 1
Trichomonas vaginalis penicillin-binding protein, putative 0.015 0.0494 0.143
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0044 0.0126 0.0308
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0179 0.0598 0.1745
Echinococcus multilocularis cathepsin b 0.1175 0.4074 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0063 0.0193 0.0533
Loa Loa (eye worm) hypothetical protein 0.0179 0.0598 0.1466
Echinococcus multilocularis potassium voltage gated channel protein 0.0044 0.0126 0.0307
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0445 0.1526 0.1526
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0033
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0023 0.0056
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0992 0.2911
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0044 0.0107
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0031 0.0056
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0044 0.0126 0.0307
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0032 0.0031
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0063 0.0193 0.0533
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0126 0.0125
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.023 0.0776 0.0776
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1175 0.4074 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0046 0.0111
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0107 0.0325
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0179 0.0598 0.1738
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.015 0.0494 0.141
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.081 0.2798 0.6867
Mycobacterium ulcerans beta-lactamase 0.015 0.0494 0.5169
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0107 0.0287
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0104 0.0459
Toxoplasma gondii kringle domain-containing protein 0.0026 0.0064 0.0144
Entamoeba histolytica cysteine proteinase, putative 0.0445 0.1526 0.5263
Toxoplasma gondii exonuclease III APE 0.0038 0.0104 0.0264
Leishmania major hypothetical protein, conserved 0.0015 0.0026 0.0036
Plasmodium vivax importin-beta 2, putative 0.0029 0.0072 0.0181
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0668 0.2302 0.565
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0126 0.0125
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Echinococcus multilocularis sodium channel protein 0.0044 0.0126 0.0307
Trypanosoma cruzi hypothetical protein, conserved 0.015 0.0494 0.118
Echinococcus granulosus hyperpolarization activated cyclic 0.0132 0.0433 0.1062
Entamoeba histolytica cysteine protease, putative 0.0445 0.1526 0.5263
Mycobacterium tuberculosis Conserved protein 0.015 0.0494 0.141
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0184 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0179 0.0598 0.1738
Echinococcus granulosus Polycystic kidney disease protein 0.0011 0.0011 0.0026
Trypanosoma brucei ISWI complex protein 0.0015 0.0026 0.0036
Echinococcus multilocularis voltage gated potassium channel 0.0044 0.0126 0.0307
Schistosoma mansoni hypothetical protein 0.0011 0.0009 0.0009
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0088 0.028 0.0686
Echinococcus granulosus lipoxygenase domain containing protein 0.0011 0.0011 0.0026
Leishmania major cathepsin L-like protease 0.0835 0.2887 1
Entamoeba histolytica hypothetical protein 0.0036 0.0098 0.0294
Onchocerca volvulus 0.0835 0.2887 1
Onchocerca volvulus 0.015 0.0494 0.168
Plasmodium falciparum plasmepsin IX 0.023 0.0776 0.2276
Echinococcus granulosus shaker cognate 0.0044 0.0126 0.0307
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2887 0.8553
Mycobacterium ulcerans regulatory protein 0.0088 0.028 0.2769
Plasmodium falciparum ataxin-2 like protein, putative 0.0012 0.0015 0.0012
Loa Loa (eye worm) voltage-dependent calcium channel 0.0044 0.0126 0.0307
Loa Loa (eye worm) hypothetical protein 0.0046 0.0133 0.0326
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0835 0.2887 0.8553
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0031 0.004
Trichomonas vaginalis adenylate cyclase type, putative 0.0063 0.0193 0.0533
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0029 0.0069
Treponema pallidum catabolite gene activator (Crp) 0.0088 0.028 0.2299
Echinococcus multilocularis voltage gated potassium channel 0.0193 0.0647 0.1588
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0011 0.0009 0.0022
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0012 0.0014 0.0034
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0051 0.0124
Trichomonas vaginalis adenylate cyclase, putative 0.0063 0.0193 0.0533
Brugia malayi cathepsin B-like cysteine proteinase 0.1175 0.4074 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0835 0.2887 1
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0016 0.0028 0.0043
Echinococcus granulosus single minded 2 0.0061 0.0186 0.0456
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0046 0.0112
Onchocerca volvulus 0.0253 0.0855 0.2933
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0044 0.0126 0.0307
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0011 0.0009 0.0022
Echinococcus multilocularis voltage dependent calcium channel 0.0044 0.0126 0.0307
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0044 0.0126 0.0125
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0067 0.0167
Trichomonas vaginalis adenylate cyclase, putative 0.0063 0.0193 0.0533
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0088 0.028 0.0652
Schistosoma mansoni GTP-binding protein alpha subunit 0.0012 0.0014 0.0013
Echinococcus multilocularis GPCR, family 2 0.0016 0.0029 0.0069
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0088 0.028 0.0922
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0179 0.0598 0.3463
Mycobacterium tuberculosis Probable conserved lipoprotein 0.015 0.0494 0.141
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0128 0.034
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0044 0.0126 0.0125
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0179 0.0598 0.0597
Loa Loa (eye worm) AGC/PKG protein kinase 0.0089 0.0282 0.0692
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Echinococcus multilocularis dna polymerase eta 0.0021 0.0047 0.0114
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0047 0.0044
Leishmania major hypothetical protein, conserved 0.015 0.0494 0.1668
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0047 0.0114
Trichomonas vaginalis adenylate cyclase, putative 0.0063 0.0193 0.0533
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0179 0.0598 0.1745
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0282 0.0282
Leishmania major regulatory subunit of protein kinase a-like protein 0.0088 0.028 0.0922
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0033
Echinococcus granulosus cathepsin L 0.0445 0.1526 0.3744
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.0685 0.0684
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0835 0.2887 0.8553
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0835 0.2887 0.8553
Echinococcus multilocularis sodium leak channel non selective protein 0.0044 0.0126 0.0307
Toxoplasma gondii transporter, cation channel family protein 0.0044 0.0126 0.0329
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0088 0.028 0.0279
Leishmania major hypothetical protein, conserved 0.0044 0.0126 0.0384
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0132 0.0433 0.0433
Schistosoma mansoni hypothetical protein 0.086 0.2973 0.2972
Trypanosoma cruzi major cysteine proteinase, putative 0.0179 0.0598 0.1435
Schistosoma mansoni voltage-gated potassium channel 0.0193 0.0647 0.0647
Echinococcus granulosus patatin phospholipase domain containing protein 0.0088 0.028 0.0686
Giardia lamblia Cathepsin B precursor 0.0179 0.0598 0.3463
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0063 0.0193 0.0533
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Toxoplasma gondii cathepsin CPC1 0.0179 0.0598 0.1735
Trypanosoma brucei cAMP response protein 1, putative 0.0088 0.028 0.0922
Echinococcus multilocularis lamin 0.0027 0.0066 0.0161
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0132 0.0433 0.1062
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0179 0.0598 0.1745
Entamoeba histolytica cysteine proteinase, putative 0.0835 0.2887 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0064 0.0155
Echinococcus granulosus phd:f box containing protein 0.0017 0.0031 0.0075
Echinococcus multilocularis potassium voltage gated channel protein 0.0044 0.0126 0.0307
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0044 0.0126 0.0307
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0992 0.2911
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0104 0.0309
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0128 0.034
Loa Loa (eye worm) calcium channel 0.0044 0.0126 0.0307
Plasmodium falciparum plasmepsin V 0.023 0.0776 0.2276
Loa Loa (eye worm) hypothetical protein 0.0017 0.0031 0.0075
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0248 0.1956
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2887 0.8553
Loa Loa (eye worm) hypothetical protein 0.0063 0.0191 0.0467
Trichomonas vaginalis glutaminase, putative 0.0273 0.0926 0.2715
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2887 0.8553
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0044 0.0126 0.0125
Entamoeba histolytica hypothetical protein 0.0036 0.0098 0.0294
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0047 0.011
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0012 0.0014 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0186 0.0513
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0031 0.0075
Brugia malayi hypothetical protein 0.023 0.0776 0.1906
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2887 0.8553
Trichomonas vaginalis adenylate cyclase, putative 0.0063 0.0193 0.0533
Schistosoma mansoni hypothetical protein 0.0011 0.0009 0.0009
Echinococcus multilocularis voltage dependent calcium channel 0.0044 0.0126 0.0307
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0038 0.0092
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0047 0.0114
Echinococcus granulosus snurportin 1 0.0305 0.1037 0.2544
Echinococcus granulosus potassium voltage gated channel protein 0.0044 0.0126 0.0307
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0029 0.0069
Mycobacterium tuberculosis Conserved protein 0.0088 0.028 0.0755
Schistosoma mansoni voltage-gated potassium channel 0.0193 0.0647 0.0647
Loa Loa (eye worm) hypothetical protein 0.0026 0.0065 0.0157
Schistosoma mansoni ap endonuclease 0.0038 0.0104 0.0103
Giardia lamblia Cathepsin B precursor 0.0179 0.0598 0.3463
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0278 0.0941 0.2309
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0104 0.0254
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0975 0.3373 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0179 0.0598 0.0597
Onchocerca volvulus 0.0044 0.0126 0.0398
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0261 0.0883 0.2167
Loa Loa (eye worm) ryanodine receptor 0.0044 0.0126 0.0307
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0053 0.0094
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0009 0.0022
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0248 0.0705
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2887 0.8553
Schistosoma mansoni ets-related 0.0222 0.0748 0.0747
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0009 0.0022
Echinococcus granulosus cathepsin L cysteine protease 0.0445 0.1526 0.3744
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0278 0.0941 0.2309
Echinococcus multilocularis zinc finger protein 0.0023 0.0053 0.0129
Loa Loa (eye worm) hypothetical protein 0.0569 0.1959 0.4808
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0179 0.0598 0.1745
Loa Loa (eye worm) acetyltransferase 0.0146 0.0482 0.1182
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0044 0.0126 0.0308
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0031 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.011
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0228 0.0558
Schistosoma mansoni loxhd1 0.0011 0.0011 0.0011
Leishmania major cathepsin L-like protease 0.0835 0.2887 1
Plasmodium falciparum plasmepsin II 0.0975 0.3373 1
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.057 0.1656
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0063 0.0193 0.0533
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0012 0.0014 0.0013
Leishmania major hypothetical protein, unknown function 0.0044 0.0126 0.0384
Plasmodium falciparum serine repeat antigen 6 0.0179 0.0598 0.1745
Brugia malayi Cathepsin L-like precursor 0.0835 0.2887 0.7086
Trypanosoma cruzi polo-like protein kinase, putative 0.0204 0.0685 0.1649
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0975 0.3373 0.8279
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.0685 0.1996
Loa Loa (eye worm) hypothetical protein 0.0266 0.09 0.2209
Echinococcus multilocularis expressed protein 0.0012 0.0014 0.0033
Trichomonas vaginalis adenylate cyclase, putative 0.0063 0.0193 0.0533
Schistosoma mansoni hypothetical protein 0.0035 0.0094 0.0093
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0179 0.0598 0.1738
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0098 0.0239
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0009 0.0022
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0044 0.0126 0.0398
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0021 0.0046 0.0113
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.0685 0.1996
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0248 0.2414
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0047 0.011
Schistosoma mansoni ran 0.0021 0.0046 0.0045
Schistosoma mansoni cathepsin s 0.0266 0.09 0.09
Echinococcus multilocularis shaker cognate 0.0044 0.0126 0.0307
Leishmania major hypothetical protein, unknown function 0.0088 0.028 0.0922
Brugia malayi cathepsin L-like cysteine proteinase 0.0179 0.0598 0.1467
Entamoeba histolytica cysteine protease, putative 0.0445 0.1526 0.5263
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.0685 0.1996
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0128 0.0348
Echinococcus multilocularis transient receptor potential cation channel 0.0044 0.0126 0.0307
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0835 0.2887 0.8553
Schistosoma mansoni voltage-gated cation channel 0.0044 0.0126 0.0125
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0126 0.0125
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0032 0.0077
Schistosoma mansoni polycystin 1-related 0.0011 0.0011 0.0011
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0029 0.0069
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.023 0.0776 0.0776
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.057 0.1656
Brugia malayi Kringle domain containing protein 0.0026 0.0064 0.0156
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Echinococcus granulosus voltage dependent calcium channel 0.0044 0.0126 0.0307
Trichomonas vaginalis D-aminoacylase, putative 0.015 0.0494 0.143
Entamoeba histolytica Ran family GTPase 0.0021 0.0046 0.0111
Trypanosoma brucei hypothetical protein, conserved 0.015 0.0494 0.1668
Echinococcus granulosus lysine specific demethylase 5A 0.0065 0.02 0.049
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0038 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0186 0.0513
Brugia malayi Protein kinase domain containing protein 0.0026 0.0064 0.0156
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.02 0.049
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Echinococcus granulosus expressed protein 0.0012 0.0014 0.0033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0992 0.2911
Brugia malayi MH2 domain containing protein 0.0008 0 0.0001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0278 0.0941 0.2309
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0179 0.0598 0.0597
Brugia malayi beta-lactamase family protein 0.015 0.0494 0.1213
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0278 0.0941 0.0941
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0088 0.028 0.0792
Brugia malayi N-terminal motif family protein 0.0088 0.028 0.0687
Schistosoma mansoni cathepsin D (A01 family) 0.2873 1 1
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0044 0.0126 0.0384
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.047 0.9439
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Brugia malayi hypothetical protein 0.0011 0.0011 0.0027
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0012 0.0014 0.0033
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0016 0.0028 0.0068
Trypanosoma brucei unspecified product 0.0015 0.0024 0.0029
Echinococcus multilocularis microtubule associated protein 2 0.069 0.238 0.584
Plasmodium falciparum plasmepsin VI 0.0975 0.3373 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0179 0.0598 0.1738
Entamoeba histolytica cysteine proteinase, putative 0.0445 0.1526 0.5263
Echinococcus granulosus TRP transient receptor potential channel 0.0044 0.0126 0.0307
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0017 0.0033 0.0079
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0044 0.0126 0.0307
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0179 0.0598 0.1738
Entamoeba histolytica cysteine protease, putative 0.0179 0.0598 0.2032
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0179 0.0598 0.1745
Trypanosoma cruzi hypothetical protein, conserved 0.015 0.0494 0.118
Trichomonas vaginalis adenylate cyclase, putative 0.0063 0.0193 0.0533
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0026 0.0064 0.0156
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0032 0.0077
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0044 0.0126 0.0308
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.011
Giardia lamblia Cysteine protease 0.0179 0.0598 0.3463
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2887 0.8553
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0012 0.0014 0.0034
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0126 0.0125
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.0992 0.3404
Brugia malayi Cathepsin L-like precursor 0.0835 0.2887 0.7086
Plasmodium falciparum serine repeat antigen 5 0.0179 0.0598 0.1745
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0883 0.2588
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0016 0.0028 0.0046
Trypanosoma brucei protein kinase A regulatory subunit 0.0088 0.028 0.0922
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0031 0.0081 0.0197
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0088 0.028 0.0687
Plasmodium falciparum cysteine proteinase falcipain 3 0.0835 0.2887 0.8554
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Plasmodium vivax vivapain-3 0.0445 0.1526 0.4506
Entamoeba histolytica cysteine proteinase, putative 0.0569 0.1959 0.677
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0014 0.0034
Giardia lamblia Cathepsin L precursor 0.0179 0.0598 0.3463
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0075
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0063 0.0193 0.0533
Brugia malayi MH2 domain containing protein 0.0119 0.0386 0.0947
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0179 0.0598 0.0597
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0063 0.0193 0.0533
Onchocerca volvulus 0.0088 0.028 0.0935
Brugia malayi PHD-finger family protein 0.0028 0.0071 0.0175
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.0193 0.0473
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.0685 0.1996
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0012 0.0014 0.0013
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0106
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0975 0.3373 1
Mycobacterium tuberculosis Conserved protein 0.015 0.0494 0.141
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0061 0.0186 0.0457
Brugia malayi glutaminase DH11.1 0.0273 0.0926 0.2273
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0179 0.0598 0.1738
Trypanosoma cruzi cAMP binding protein, putative 0.0088 0.028 0.0652
Echinococcus granulosus ETS transcription factor Elf 1 0.0011 0.0009 0.0022
Echinococcus multilocularis RUN 0.0011 0.0011 0.0026
Loa Loa (eye worm) G protein alpha subunit 3 0.0012 0.0014 0.0033
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0063 0.0193 0.0533
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0031 0.0081 0.0197
Trypanosoma cruzi major cysteine proteinase, putative 0.0179 0.0598 0.1435
Loa Loa (eye worm) hypothetical protein 0.0044 0.0127 0.031
Loa Loa (eye worm) glutaminase 2 0.0273 0.0926 0.2272
Schistosoma mansoni zinc finger protein 0.0015 0.0026 0.0025
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0126 0.0329
Giardia lamblia Cathepsin L precursor 0.0179 0.0598 0.3463
Trypanosoma cruzi cysteine peptidase, putative 0.0835 0.2887 0.7075
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0088 0.028 0.0686
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0278 0.0941 0.0941
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0012 0.0014 0.0013
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0051 0.0124
Brugia malayi Importin beta-1 subunit 0.0029 0.0072 0.0177
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0012 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0617 0.2126 0.5218
Trypanosoma cruzi ISWI complex protein 0.0015 0.0026 0.0026
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0066 0.0161
Schistosoma mansoni tar DNA-binding protein 0.0031 0.008 0.008
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0063 0.0193 0.0533
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0193 0.0472
Echinococcus granulosus voltage gated potassium channel 0.0044 0.0126 0.0307
Echinococcus granulosus ETS domain containing protein Elk 1 0.0011 0.0009 0.0022
Trypanosoma cruzi cysteine proteinase, putative 0.0445 0.1526 0.3722
Loa Loa (eye worm) voltage-gated calcium channel 0.0044 0.0126 0.0307
Onchocerca volvulus 0.0179 0.0598 0.204
Entamoeba histolytica cysteine protease, putative 0.0445 0.1526 0.5263
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0179 0.0598 0.1745
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0067 0.0167
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0044 0.0126 0.0308
Entamoeba histolytica cysteine proteinase 1, putative 0.0445 0.1526 0.5263
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0044 0.0126 0.0125
Onchocerca volvulus 0.015 0.0494 0.168
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0835 0.2887 1
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0153 0.0375
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0044 0.0126 0.0307
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0046 0.0103
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0012 0.0014 0.0033
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0132 0.0433 0.0433
Echinococcus granulosus dna polymerase kappa 0.0021 0.0047 0.0114
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0179 0.0598 0.1467
Echinococcus granulosus two pore calcium channel protein 1 0.0044 0.0126 0.0307
Trichomonas vaginalis adenylate cyclase type III, putative 0.0063 0.0193 0.0533
Loa Loa (eye worm) RNA binding protein 0.0031 0.008 0.0195
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0184 0.0463
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0098 0.0098
Trypanosoma cruzi Flagellar Member 6 0.0088 0.028 0.0652
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0132 0.0433 0.0433
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0088 0.028 0.0686
Schistosoma mansoni DNA polymerase eta 0.0021 0.0047 0.0046
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0016 0.0028 0.0046
Trichomonas vaginalis D-aminoacylase, putative 0.015 0.0494 0.143
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0624 0.2149 0.6354
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0668 0.2302 0.5649
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.011
Brugia malayi jmjC domain containing protein 0.0017 0.0031 0.0077
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0012 0.0014 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0024 0.0029
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0044 0.0126 0.0307
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0487 0.1673 0.4084
Echinococcus granulosus ETS transcription factor Elf 5 0.0011 0.0009 0.0022
Brugia malayi Cathepsin L-like precursor 0.0835 0.2887 0.7086
Toxoplasma gondii cathepsin B 0.0487 0.1673 0.4937
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0047 0.016
Trypanosoma cruzi cysteine proteinase, putative 0.0445 0.1526 0.3722
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0063 0.0193 0.0533
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0012 0.0014 0.0033
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0445 0.1526 0.1526
Leishmania major cyclic nucleotide-binding protein-like protein 0.0088 0.028 0.0922
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0044 0.0126 0.0307
Brugia malayi olfactory channel protein osm-9 0.0044 0.0126 0.0308
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0083 0.0204
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0024 0.0029
Loa Loa (eye worm) hypothetical protein 0.0049 0.0143 0.035
Echinococcus granulosus transient receptor potential gamma protein 0.0044 0.0126 0.0307
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0186 0.0513
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0012 0.0014 0.0034
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0111
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0088 0.028 0.0279
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Trichomonas vaginalis conserved hypothetical protein 0.0179 0.0598 0.1738
Loa Loa (eye worm) hypothetical protein 0.0569 0.1959 0.4808
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0835 0.2887 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0047 0.0114
Echinococcus granulosus lipoxygenase domain containing protein 0.0011 0.0011 0.0026
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0021 0.0046 0.0113
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0126 0.0125
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0132 0.0433 0.1062
Brugia malayi cathepsin L precursor 0.0179 0.0598 0.1467
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0012 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Schistosoma mansoni rab6-interacting 0.0011 0.0011 0.0011
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0015 0.0025 0.006
Schistosoma mansoni lipoxygenase 0.0011 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0106 0.0259
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0835 0.2887 0.7086
Entamoeba histolytica cysteine protease, putative 0.0445 0.1526 0.5263
Giardia lamblia Cathepsin L-like protease 0.0179 0.0598 0.3463
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0278 0.0941 0.0941
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0038
Plasmodium falciparum plasmepsin IV 0.0975 0.3373 1
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0975 0.3373 0.8279
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0835 0.2887 0.7086
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0668 0.2302 0.5649
Entamoeba histolytica cysteine proteinase, putative 0.0445 0.1526 0.5263
Plasmodium vivax vivapain-2 0.0835 0.2887 0.8554
Giardia lamblia Cathepsin L precursor 0.0179 0.0598 0.3463
Echinococcus granulosus geminin 0.086 0.2973 0.7296
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0184 0.1697
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0179 0.0598 0.1745
Loa Loa (eye worm) hypothetical protein 0.015 0.0494 0.1212
Schistosoma mansoni 60S ribosomal protein L21 0.0105 0.034 0.0339
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0261 0.0883 0.2168
Toxoplasma gondii preprocathepsin c precursor, putative 0.0179 0.0598 0.1735
Echinococcus granulosus potassium voltage gated channel protein 0.0044 0.0126 0.0307
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0044 0.0126 0.0308
Leishmania major protein kinase A regulatory subunit, putative 0.0088 0.028 0.0922
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0072 0.0198
Entamoeba histolytica hypothetical protein 0.0036 0.0098 0.0294
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0204 0.0685 0.1679
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0014 0.0034
Echinococcus multilocularis potassium large conductance calcium activated 0.0044 0.0126 0.0307
Plasmodium vivax serine-repeat antigen (SERA) 0.0179 0.0598 0.1745
Leishmania major proteasome regulatory non-ATP-ase subunit 11, putative,19S proteasome regulatory subunit, Metallo- peptidase, Clan MP, Family M6 0.0016 0.0028 0.0046
Treponema pallidum cyclic nucleotide binding protein 0.0088 0.028 0.2299
Echinococcus granulosus GPCR family 2 0.0016 0.0029 0.0069
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0044 0.0126 0.0307
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0835 0.2887 0.7086
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0088 0.028 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0193 0.0647 0.1588
Schistosoma mansoni cathepsin S (C01 family) 0.0179 0.0598 0.0597
Plasmodium falciparum plasmepsin VII 0.023 0.0776 0.2276
Trypanosoma brucei cysteine peptidase C (CPC) 0.0487 0.1673 0.5773
Mycobacterium tuberculosis Probable lipase LipD 0.015 0.0494 0.141
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0088 0.028 0.0755
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0031 0.0075
Treponema pallidum fructose-bisphosphate aldolase 0.0292 0.0992 1
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0088 0.028 0.0935
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0031 0.0075
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.057 0.1656
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0044 0.0126 0.0272
Echinococcus multilocularis musashi 0.0027 0.0066 0.0161
Plasmodium vivax plasmepsin IV, putative 0.0975 0.3373 1
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0107 0.0481
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2887 0.8553
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 11, putative 0.0016 0.0028 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0835 0.2887 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0047 0.0078
Loa Loa (eye worm) hypothetical protein 0.0193 0.0647 0.1588
Brugia malayi intermediate filament protein 0.0027 0.0066 0.0163
Brugia malayi Cathepsin L-like precursor 0.0835 0.2887 0.7086
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0029 0.0069
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0088 0.028 0.0788
Brugia malayi Papain family cysteine protease containing protein 0.0179 0.0598 0.1467
Schistosoma mansoni cathepsin F (C01 family) 0.0569 0.1959 0.1959
Loa Loa (eye worm) hypothetical protein 0.0071 0.0219 0.0536
Plasmodium falciparum serine repeat antigen 4 0.0179 0.0598 0.1745
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.028 0.0792
Schistosoma mansoni cathepsin B (C01 family) 0.0179 0.0598 0.0597
Loa Loa (eye worm) aspartic protease BmAsp-1 0.023 0.0776 0.1905
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.011
Schistosoma mansoni transient receptor potential channel 0.0044 0.0126 0.0125
Schistosoma mansoni hypothetical protein 0.0044 0.0126 0.0125
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0031 0.0031
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0153 0.0375
Echinococcus multilocularis calcium activated potassium channel 0.0045 0.0128 0.0313
Echinococcus granulosus hyperpolarization activated cyclic 0.0132 0.0433 0.1062
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0132 0.0433 0.1248
Echinococcus multilocularis tissue type plasminogen activator 0.0026 0.0064 0.0155
Echinococcus multilocularis tar DNA binding protein 0.0031 0.008 0.0195
Brugia malayi Doublecortin family protein 0.0011 0.0011 0.0027
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0046 0.0111
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Onchocerca volvulus 0.0012 0.0014 0.001
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0088 0.028 0.0755
Giardia lamblia Cathepsin L precursor 0.0179 0.0598 0.3463
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0098 0.0239
Schistosoma mansoni ran 0.0021 0.0046 0.0045
Brugia malayi MH1 domain containing protein 0.0008 0 0.0001
Entamoeba histolytica cysteine protease, putative 0.0445 0.1526 0.5263
Giardia lamblia Cathepsin B precursor 0.0487 0.1673 1
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0088 0.028 0.0686
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0186 0.0513
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0098 0.024
Plasmodium vivax SET domain protein, putative 0.0032 0.0083 0.0215
Schistosoma mansoni vesicular amine transporter 0.0044 0.0126 0.0125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0835 0.2887 0.8553
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0014 0.0013
Toxoplasma gondii proteasome regulatory subunit 0.0021 0.0046 0.0092
Echinococcus granulosus short transient receptor potential channel 6 0.0044 0.0126 0.0307
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0028
Treponema pallidum catabolite gene activator 0.0088 0.028 0.2299
Entamoeba histolytica hypothetical protein 0.0179 0.0598 0.2032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2887 0.8553
Loa Loa (eye worm) hypothetical protein 0.0088 0.028 0.0686
Echinococcus granulosus ewsr:fli fusion protein type 0.0011 0.0009 0.0022
Echinococcus granulosus cathepsin L 0.0179 0.0598 0.1466
Echinococcus granulosus protein C ets 2 0.0011 0.0009 0.0022
Brugia malayi hypothetical protein 0.0036 0.0098 0.0241
Onchocerca volvulus Glucosylceramidase homolog 0.0171 0.057 0.1944
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0104 0.0218
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0602 0.1751
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0012 0.0014 0.0033
Giardia lamblia Cathepsin B precursor 0.0179 0.0598 0.3463
Echinococcus granulosus RUN 0.0011 0.0011 0.0026
Giardia lamblia Kinase, PLK 0.0204 0.0685 0.399
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0179 0.0598 0.1738
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2887 0.8553
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2887 0.8553
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0193 0.0647 0.1589
Echinococcus granulosus cathepsin b 0.1175 0.4074 1
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0325 0.0926
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0088 0.028 0.0922
Leishmania major hypothetical protein, conserved 0.0026 0.0064 0.0169
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0031 0.0075
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0179 0.0598 0.0597
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1175 0.4074 0.4074
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0094 0.023
Echinococcus granulosus intermediate filament protein 0.0027 0.0066 0.0161
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0835 0.2887 0.8553
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0044 0.0126 0.0125
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0044 0.0126 0.0307
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0105
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1175 0.4074 0.4074
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0098 0.024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0992 0.2911
Onchocerca volvulus 0.0617 0.2126 0.7355
Loa Loa (eye worm) TAR-binding protein 0.0031 0.008 0.0195
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0184 0.1697
Onchocerca volvulus Serine\/threonine kinase homolog 0.0204 0.0685 0.2342
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0179 0.0598 0.1738
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0126 0.0125
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0026
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0044 0.0126 0.0307
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0835 0.2887 0.8553
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0044 0.0126 0.0125
Giardia lamblia Encystation-specific protease 0.0179 0.0598 0.3463
Echinococcus multilocularis ewsr:fli fusion protein type 0.0011 0.0009 0.0022
Echinococcus granulosus two pore calcium channel protein 2 0.0044 0.0126 0.0307
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0179 0.0598 0.1466
Echinococcus multilocularis ETS transcription factor Elf 1 0.0011 0.0009 0.0022
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0017 0.0033 0.0079
Schistosoma mansoni voltage-gated potassium channel 0.0729 0.2516 0.2516
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0835 0.2887 1
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0248 0.0248
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0011 0.0009 0.0009
Onchocerca volvulus Cathepsin F homolog 0.0835 0.2887 1
Schistosoma mansoni rab6-interacting 0.0011 0.0011 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0179 0.0598 0.1738
Loa Loa (eye worm) hypothetical protein 0.015 0.0494 0.1212
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.02 0.0199
Onchocerca volvulus 0.0032 0.0083 0.0252
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0012 0.0014 0.0033
Brugia malayi Cathepsin L-like cysteine proteinase 0.0569 0.1959 0.4808
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0047 0.0046
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0012 0.0014 0.0013
Loa Loa (eye worm) doublecortin family protein 0.0011 0.0011 0.0026
Schistosoma mansoni voltage-dependent calcium channel 0.0044 0.0126 0.0125
Echinococcus granulosus transient receptor potential cation channel 0.0044 0.0126 0.0307
Loa Loa (eye worm) hypothetical protein 0.0132 0.0433 0.1062
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0204 0.0685 0.1679
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0179 0.0598 0.1738
Entamoeba histolytica hypothetical protein 0.0023 0.0053 0.0137
Plasmodium falciparum serine repeat antigen 7 0.0179 0.0598 0.1745
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0088 0.028 0.0792
Plasmodium falciparum plasmepsin III 0.023 0.0776 0.2276
Toxoplasma gondii transporter, cation channel family protein 0.0044 0.0126 0.0329
Plasmodium vivax vivapain-1 0.0445 0.1526 0.4506
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0044 0.0126 0.0307
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0014 0.0013
Brugia malayi DNA-binding protein D-ETS-3 0.0011 0.0009 0.0023
Schistosoma mansoni transient receptor potential channel 0.0044 0.0126 0.0125
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0063 0.0193 0.0533
Plasmodium vivax vivapain-2 0.0835 0.2887 0.8554
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0053 0.0117
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0088 0.028 0.0686
Onchocerca volvulus 0.015 0.0494 0.168
Mycobacterium ulcerans hypothetical protein 0.0088 0.028 0.2769
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.015 0.0494 0.1212
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0063 0.0193 0.0533
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0047 0.0044
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0305 0.1037 0.2544
Brugia malayi hypothetical protein 0.023 0.0776 0.1906
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0044 0.0126 0.0308
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0153 0.0368
Brugia malayi Bromodomain containing protein 0.0078 0.0246 0.0604
Entamoeba histolytica cysteine protease, putative 0.0445 0.1526 0.5263
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0044 0.0126 0.0329
Loa Loa (eye worm) voltage-gated potassium channel 0.0044 0.0126 0.0307
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0992 0.2911
Echinococcus multilocularis Polycystic kidney disease protein 0.0011 0.0011 0.0026
Echinococcus granulosus voltage gated hydrogen channel 1 0.0044 0.0126 0.0307
Leishmania major cathepsin L-like protease 0.0835 0.2887 1
Plasmodium falciparum serine repeat antigen 9 0.0179 0.0598 0.1745
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0143 0.0142
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0179 0.0598 0.3463
Brugia malayi Cathepsin L-like precursor 0.0569 0.1959 0.4808
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0014 0.0034
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0031 0.004
Onchocerca volvulus 0.0569 0.1959 0.6773
Loa Loa (eye worm) hypothetical protein 0.0179 0.0598 0.1466
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0132 0.0433 0.1062
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0044 0.0126 0.0307
Brugia malayi ion channel NompC 0.0044 0.0126 0.0308
Schistosoma mansoni voltage-gated potassium channel 0.0132 0.0433 0.0433
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0089 0.0282 0.0692
Echinococcus granulosus cGMP dependent protein kinase 1 0.0089 0.0282 0.0692
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0184 0.1697
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.015 0.0368
Brugia malayi Bromodomain containing protein 0.0042 0.0118 0.029
Mycobacterium ulcerans esterase/lipase LipP 0.015 0.0494 0.5169
Loa Loa (eye worm) hypothetical protein 0.0021 0.0047 0.0114
Schistosoma mansoni zinc finger protein 0.0023 0.0053 0.0052
Echinococcus granulosus tar DNA binding protein 0.0031 0.008 0.0195
Echinococcus granulosus transient receptor potential cation channel 0.0044 0.0126 0.0307
Plasmodium falciparum cysteine repeat modular protein 1 0.0026 0.0064 0.0156
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0047 0.011
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0033
Schistosoma mansoni hypothetical protein 0.0026 0.0064 0.0063
Trypanosoma cruzi hypothetical protein, conserved 0.0088 0.028 0.0652
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.015 0.0367
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0072 0.0176
Mycobacterium ulcerans lipase LipD 0.015 0.0494 0.5169
Schistosoma mansoni tar DNA-binding protein 0.0031 0.008 0.008
Echinococcus multilocularis lipoxygenase domain containing protein 0.0011 0.0011 0.0026
Echinococcus multilocularis lamin dm0 0.0027 0.0066 0.0161
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0033
Brugia malayi RNA, U transporter 1 0.0081 0.0256 0.0628
Echinococcus granulosus cGMP dependent protein kinase 0.0089 0.0282 0.0692
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0021 0.0046 0.0104
Trypanosoma brucei unspecified product 0.0015 0.0024 0.0029
Giardia lamblia Cathepsin B precursor 0.0179 0.0598 0.3463
Schistosoma mansoni cathepsin C 0.0179 0.0598 0.0597
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0044 0.0126 0.0307
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0047 0.0078
Echinococcus multilocularis hyperpolarization activated cyclic 0.0132 0.0433 0.1062
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.015 0.0368
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0021 0.0046 0.0104
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0089 0.0282 0.0795
Trichomonas vaginalis penicillin-binding protein, putative 0.015 0.0494 0.143
Schistosoma mansoni two-pore calcium channel 0.0044 0.0126 0.0125
Echinococcus granulosus cysteine protease 0.0445 0.1526 0.3744
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0044 0.0126 0.0125
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.023 0.0776 0.0776
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0179 0.0598 0.0597
Trypanosoma brucei unspecified product 0.0021 0.0047 0.011
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0193 0.0533
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0088 0.028 0.0686
Trichomonas vaginalis adenylate cyclase, putative 0.0063 0.0193 0.0533
Loa Loa (eye worm) hypothetical protein 0.0266 0.09 0.2209
Brugia malayi jmjC domain containing protein 0.0017 0.0031 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0186 0.0513
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0063 0.0193 0.0533
Schistosoma mansoni hypothetical protein 0.0088 0.028 0.0279
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0248 0.0608
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.015 0.0494 0.141
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0044 0.0126 0.0308
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0104 0.0255
Brugia malayi jmjC domain containing protein 0.0017 0.0031 0.0077
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0044 0.0126 0.0125
Echinococcus granulosus calcium activated potassium channel 0.0045 0.0128 0.0313
Loa Loa (eye worm) fibroinase 0.0835 0.2887 0.7086
Echinococcus multilocularis transient receptor potential cation channel 0.0044 0.0126 0.0307
Mycobacterium leprae conserved hypothetical protein 0.015 0.0494 1
Giardia lamblia Cysteine protease 0.0179 0.0598 0.3463
Loa Loa (eye worm) proteasome 26S subunit 0.0016 0.0028 0.0068
Toxoplasma gondii hypothetical protein 0.0027 0.0067 0.0155
Loa Loa (eye worm) hypothetical protein 0.0017 0.0031 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0193 0.0533
Loa Loa (eye worm) hypothetical protein 0.0569 0.1959 0.4808
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0088 0.028 0.08
Trypanosoma cruzi cysteine peptidase, putative 0.0835 0.2887 0.7075
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0044 0.0126 0.0125
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.046 0.1127
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0088 0.028 0.0279
Brugia malayi Cyclic-nucleotide gated cation channel 0.0132 0.0433 0.1063
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0445 0.1526 0.3722
Giardia lamblia Cathepsin B precursor 0.0487 0.1673 1
Echinococcus granulosus potassium large conductance calcium activated 0.0044 0.0126 0.0307
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0104 0.0394
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.023 0.0776 0.0776
Brugia malayi Cathepsin L-like precursor 0.0266 0.09 0.221
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0029 0.007
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0992 0.2911
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0088 0.028 0.0279
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0835 0.2887 1
Trypanosoma cruzi cruzipain precursor, putative 0.0266 0.09 0.2181
Loa Loa (eye worm) hypothetical protein 0.0017 0.0031 0.0075
Entamoeba histolytica cysteine protease, putative 0.0179 0.0598 0.2032
Trypanosoma brucei polo-like protein kinase 0.0204 0.0685 0.2331
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0132 0.0433 0.1062
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Loa Loa (eye worm) hypothetical protein 0.0051 0.015 0.0367
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0132 0.0433 0.1248
Onchocerca volvulus 0.0026 0.0064 0.0183
Brugia malayi cathepsin L-like precursor 0.0569 0.1959 0.4808
Echinococcus multilocularis transient receptor potential cation channel 0.0044 0.0126 0.0307
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.047 0.4901
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.011
Plasmodium vivax unspecified product 0.0179 0.0598 0.1745
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0128 0.0336
Brugia malayi Pepsin A precursor 0.023 0.0776 0.1906
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0016 0.0028 0.0043
Brugia malayi Eukaryotic aspartyl protease family protein 0.023 0.0776 0.1906
Brugia malayi hypothetical protein 0.0012 0.0014 0.0034
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0063 0.0193 0.0533
Echinococcus granulosus sodium channel protein 0.0044 0.0126 0.0307
Entamoeba histolytica cysteine protease, putative 0.0445 0.1526 0.5263
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0044 0.0126 0.0384
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0278 0.0941 0.2309
Mycobacterium tuberculosis Probable hydrolase 0.015 0.0494 0.141
Echinococcus granulosus potassium voltage gated channel protein 0.0044 0.0126 0.0307
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0088 0.028 0.0279
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0028
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Schistosoma mansoni tar DNA-binding protein 0.0031 0.008 0.008
Trichomonas vaginalis adenylate cyclase, putative 0.0063 0.0193 0.0533
Schistosoma mansoni memapsin-2 (A01 family) 0.023 0.0776 0.0776
Entamoeba histolytica hypothetical protein 0.0036 0.0098 0.0294
Echinococcus multilocularis short transient receptor potential channel 6 0.0044 0.0126 0.0307
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0186 0.0513
Echinococcus multilocularis short transient receptor potential channel 6 0.0044 0.0126 0.0307
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0063 0.0193 0.0533
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0278 0.0941 0.2309
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0088 0.028 0.0788
Plasmodium vivax JmjC domain containing protein 0.0017 0.0031 0.006
Schistosoma mansoni ryanodine receptor related 0.0044 0.0126 0.0125
Brugia malayi G-protein alpha subunit 0.0012 0.0014 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.011
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0088 0.028 0.0788
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0044 0.0126 0.0308
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1175 0.4074 0.4074
Leishmania major DNA polymerase kappa, putative 0.0021 0.0047 0.011
Schistosoma mansoni ets 0.0011 0.0009 0.0009
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.02 0.0199
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0044 0.0126 0.0307
Plasmodium vivax aspartyl proteinase, putative 0.023 0.0776 0.2276
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0179 0.0598 0.1738
Echinococcus multilocularis expressed conserved protein 0.0089 0.0282 0.0692
Echinococcus multilocularis cathepsin L cysteine protease 0.0835 0.2887 0.7086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0179 0.0598 0.1738
Echinococcus multilocularis potassium voltage gated channel protein 0.0044 0.0126 0.0307
Onchocerca volvulus 0.0088 0.028 0.0935
Mycobacterium ulcerans hypothetical protein 0.0088 0.028 0.2769
Loa Loa (eye worm) hypothetical protein 0.0179 0.0598 0.1466
Schistosoma mansoni GTP-binding protein alpha subunit 0.0012 0.0014 0.0013
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0126 0.0125
Onchocerca volvulus 0.0835 0.2887 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0248 0.0694
Brugia malayi beta-lactamase family protein 0.015 0.0494 0.1213
Brugia malayi Papain family cysteine protease containing protein 0.0179 0.0598 0.1467
Schistosoma mansoni gabp alpha 0.0073 0.0228 0.0227
Brugia malayi Egg laying defective protein 4 0.0089 0.0282 0.0693
Mycobacterium tuberculosis Conserved hypothetical protein 0.0088 0.028 0.0755
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0153 0.0368
Echinococcus granulosus transient receptor potential cation channel 0.0044 0.0126 0.0307
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.011
Mycobacterium leprae Conserved hypothetical protein 0.0088 0.028 0.4979
Loa Loa (eye worm) hypothetical protein 0.0975 0.3373 0.8279
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0036
Brugia malayi hypothetical protein 0.0044 0.0126 0.0308
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0569 0.1959 0.579
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0029 0.007
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0012 0.0014 0.0033
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0088 0.028 0.0686
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Plasmodium falciparum plasmepsin I 0.0975 0.3373 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0104 0.0276
Plasmodium falciparum serine repeat antigen 2 0.0179 0.0598 0.1745
Brugia malayi Cathepsin L-like precursor 0.0569 0.1959 0.4808
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0044 0.0126 0.0308
Loa Loa (eye worm) cathepsin B 0.0487 0.1673 0.4106
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0204 0.0685 0.1679
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0044 0.0126 0.0307
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0266 0.09 0.2209
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0011 0.0009 0.0022
Schistosoma mansoni importin beta-1 0.0029 0.0072 0.0072
Schistosoma mansoni intermediate filament proteins 0.0027 0.0066 0.0066
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0063 0.0193 0.0533
Giardia lamblia Cathepsin L-like protease 0.0179 0.0598 0.3463
Loa Loa (eye worm) hypothetical protein 0.0035 0.0094 0.0229
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0835 0.2887 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0079 0.0194
Leishmania major hypothetical protein, conserved 0.0088 0.028 0.0922
Leishmania major hypothetical protein, conserved 0.0088 0.028 0.0922
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0179 0.0598 0.1745
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0044 0.0126 0.0272
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0032 0.0031
Brugia malayi Probable ClpP-like protease 0.0079 0.0248 0.0609
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Mycobacterium tuberculosis Probable esterase LipL 0.015 0.0494 0.141
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0126 0.0125
Toxoplasma gondii hypothetical protein 0.0044 0.0126 0.0329
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0104 0.0268
Echinococcus multilocularis ets variant gene 4 0.0011 0.0009 0.0022
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0022
Echinococcus granulosus cathepsin l1 0.0835 0.2887 0.7086
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0104 0.0309
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0063 0.0193 0.0533
Echinococcus multilocularis transient receptor potential cation channel 0.0044 0.0126 0.0307
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0445 0.1526 0.1526
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0047 0.0114
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0031 0.0048
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0088 0.028 0.0279
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0956 0.3307 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0029 0.0069
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0179 0.0598 0.3463
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0179 0.0598 0.0597
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0031 0.0048
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0883 0.2588
Plasmodium vivax aspartyl protease, putative 0.023 0.0776 0.2276
Toxoplasma gondii hypothetical protein 0.0044 0.0126 0.0329
Entamoeba histolytica cysteine protease, putative 0.0835 0.2887 1
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0012 0.0014 0.0033
Brugia malayi cathepsin Z-like cysteine proteinase 0.0179 0.0598 0.1467
Echinococcus multilocularis transfer RNA-Gly 0.0044 0.0126 0.0307
Loa Loa (eye worm) hypothetical protein 0.0179 0.0598 0.1466
Leishmania major protein kinase, putative 0.0089 0.0282 0.093
Trichomonas vaginalis adenylate cyclase type, putative 0.0063 0.0193 0.0533
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.015 0.0494 0.0494
Echinococcus multilocularis transient receptor potential cation channel 0.0044 0.0126 0.0307
Toxoplasma gondii aspartyl protease ASP3 0.023 0.0776 0.2267
Echinococcus granulosus sodium leak channel non selective protein 0.0044 0.0126 0.0307
Giardia lamblia Cysteine protease 0.0179 0.0598 0.3463
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0047 0.011
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0063 0.0193 0.0533
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0028
Giardia lamblia Cathepsin B precursor 0.0179 0.0598 0.3463
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0132 0.0433 0.0433
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0021 0.0046 0.0112
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.015 0.0494 0.5169
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0062 0.0189 0.0604
Entamoeba histolytica cysteine protease, putative 0.0179 0.0598 0.2032
Schistosoma mansoni ets-related 0.0011 0.0009 0.0009
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.0482 0.1182
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0602 0.1751
Echinococcus granulosus cathepsin l cysteine peptidase 0.0835 0.2887 0.7086
Giardia lamblia Cathepsin L precursor 0.0179 0.0598 0.3463
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0126 0.0125
Toxoplasma gondii ABC1 family protein 0.015 0.0494 0.1427
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0047 0.0078
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0248 0.0705
Brugia malayi serine/threonine-protein kinase plk-2 0.0204 0.0685 0.168
Brugia malayi hypothetical protein 0.0011 0.0011 0.0027
Trypanosoma cruzi cysteine peptidase, putative 0.0835 0.2887 0.7075
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.0685 0.1996
Echinococcus multilocularis cysteine protease 0.0835 0.2887 0.7086
Loa Loa (eye worm) hypothetical protein 0.0179 0.0598 0.1466
Brugia malayi transcription factor E74 isoform 0.0011 0.0009 0.0023
Mycobacterium ulcerans glutaminase 0.0273 0.0926 1
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0088 0.028 0.0279
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0012 0.0014 0.0033
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0063 0.0193 0.0533
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0024 0.0029
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0044 0.0126 0.0307
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0835 0.2887 0.8553
Leishmania major cathepsin L-like protease 0.0835 0.2887 1
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0487 0.1673 0.5773
Toxoplasma gondii transporter, cation channel family protein 0.0044 0.0126 0.0329
Brugia malayi fibroinase precursor 0.0179 0.0598 0.1467
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.0992 0.3404
Brugia malayi MH2 domain containing protein 0.0008 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.023 0.0776 0.1905
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0835 0.2887 0.8553
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0104 0.0268
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0012 0.0014 0.0013
Plasmodium vivax aspartyl protease, putative 0.023 0.0776 0.2276
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0047 0.0114
Entamoeba histolytica cysteine protease, putative 0.0445 0.1526 0.5263
Trypanosoma brucei cAMP binding protein, putative 0.0088 0.028 0.0922
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0047 0.011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0445 0.1526 0.4501
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0132 0.0433 0.1062
Plasmodium falciparum cysteine proteinase falcipain 1 0.0445 0.1526 0.4506
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0883 0.2588
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0104 0.0798
Leishmania major cathepsin L-like protease 0.0835 0.2887 1
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0047 0.0115
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0088 0.028 0.08
Schistosoma mansoni lamin 0.0027 0.0066 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0193 0.0533
Leishmania major protein kinase, putative 0.0089 0.0282 0.093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0445 0.1526 0.4501
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0487 0.1673 0.1673
Echinococcus multilocularis lipoxygenase domain containing protein 0.0011 0.0011 0.0026
Brugia malayi Fli-1 protein 0.0222 0.0748 0.1836
Brugia malayi Pre-SET motif family protein 0.0032 0.0083 0.0205
Trichomonas vaginalis set domain proteins, putative 0.0253 0.0855 0.2502
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0975 0.3373 0.8279
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0282 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0186 0.0513
Brugia malayi Cathepsin L-like precursor 0.0835 0.2887 0.7086
Loa Loa (eye worm) glutaminase 0.0273 0.0926 0.2272
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0282 0.0282
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0248 0.0694
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0569 0.1959 0.4789
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0179 0.0598 0.1745
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0132 0.0433 0.1062
Brugia malayi cation channel family protein 0.0044 0.0126 0.0308
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0126 0.0125
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.057 0.1656
Trichomonas vaginalis adenylate cyclase, putative 0.0063 0.0193 0.0533
Echinococcus multilocularis geminin 0.086 0.2973 0.7296
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0835 0.2887 0.8554
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0668 0.2302 0.5649
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0038
Echinococcus multilocularis two pore calcium channel protein 2 0.0044 0.0126 0.0307
Leishmania major hypothetical protein, conserved 0.0017 0.0031 0.0056
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0992 0.2911
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0179 0.0598 0.1466
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0278 0.0941 0.231
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0044 0.0126 0.0398
Trypanosoma cruzi protein kinase A regulatory subunit 0.0088 0.028 0.0652
Echinococcus multilocularis cathepsin L 0.0179 0.0598 0.1466
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Echinococcus multilocularis cathepsin L cysteine protease 0.0835 0.2887 0.7086
Entamoeba histolytica cysteine proteinase, putative 0.0835 0.2887 1
Schistosoma mansoni cathepsin F (C01 family) 0.0835 0.2887 0.2887
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0012 0.0014 0.0033
Onchocerca volvulus Cathepsin L homolog 0.0179 0.0598 0.204
Echinococcus multilocularis two pore calcium channel protein 1 0.0044 0.0126 0.0307
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0835 0.2887 0.8554
Echinococcus granulosus voltage dependent calcium channel 0.0044 0.0126 0.0307
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.023 0.0776 0.0776
Mycobacterium ulcerans hypothetical protein 0.0088 0.028 0.2769
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0044 0.0126 0.0307
Treponema pallidum cyclic nucleotide binding protein 0.0088 0.028 0.2299
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0044 0.0126 0.0125
Brugia malayi RNA binding protein 0.0031 0.008 0.0197
Echinococcus multilocularis transient receptor potential gamma protein 0.0044 0.0126 0.0307
Plasmodium vivax aspartyl proteinase, putative 0.0975 0.3373 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0047 0.011
Brugia malayi Papain family cysteine protease containing protein 0.0445 0.1526 0.3745
Mycobacterium tuberculosis Conserved protein 0.015 0.0494 0.141
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0028
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0009 0.0022
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0088 0.028 0.0792
Loa Loa (eye worm) ion channel NompC 0.0044 0.0126 0.0307
Echinococcus granulosus cGMP dependent protein kinase 1 0.0089 0.0282 0.0692
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0088 0.028 0.0687
Leishmania major cathepsin L-like protease 0.0835 0.2887 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0179 0.0598 0.2032
Giardia lamblia Hypothetical protein 0.0179 0.0598 0.3463
Brugia malayi Ets-domain containing protein 0.0073 0.0228 0.0559
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0044 0.0126 0.0307
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0179 0.0598 0.1738
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0031 0.0075
Schistosoma mansoni calcium-activated potassium channel 0.0044 0.0126 0.0125
Onchocerca volvulus 0.0012 0.0014 0.001
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0063 0.0193 0.0533
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0088 0.028 0.0279
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0046 0.0091
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.057 0.1656
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.0482 0.1183
Echinococcus granulosus histone lysine methyltransferase setb 0.0049 0.0143 0.035
Brugia malayi hypothetical protein 0.0012 0.0015 0.0037
Mycobacterium leprae Probable lipase LipE 0.015 0.0494 1
Mycobacterium ulcerans transcriptional regulatory protein 0.0088 0.028 0.2769
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0017 0.0033 0.008
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0016 0.0028 0.0043
Onchocerca volvulus 0.023 0.0776 0.2661
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0112
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0088 0.028 0.0686
Schistosoma mansoni microtubule-associated protein tau 0.069 0.238 0.2379
Schistosoma mansoni lamin 0.0027 0.0066 0.0066
Brugia malayi Pre-SET motif family protein 0.0222 0.0747 0.1834
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0053 0.0117
Echinococcus granulosus zinc finger protein 0.0023 0.0053 0.0129
Brugia malayi Papain family cysteine protease containing protein 0.0445 0.1526 0.3745
Loa Loa (eye worm) hypothetical protein 0.0179 0.0598 0.1466
Onchocerca volvulus 0.023 0.0776 0.2661
Trypanosoma cruzi cysteine peptidase, putative 0.0835 0.2887 0.7075
Loa Loa (eye worm) hypothetical protein 0.0579 0.1994 0.4894
Brugia malayi Papain family cysteine protease containing protein 0.0179 0.0598 0.1467
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0184 0.0184
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0126 0.0125
Trichomonas vaginalis adenylate cyclase type III, putative 0.0063 0.0193 0.0533
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0044 0.0126 0.0308
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0228 0.0558
Echinococcus granulosus lamin 0.0027 0.0066 0.0161
Brugia malayi Smad1 0.0008 0 0.0001
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0031 0.0031
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0126 0.0125
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0088 0.028 0.0792
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.015 0.0494 0.1213
Brugia malayi aspartic protease BmAsp-2, identical 0.023 0.0776 0.1906
Schistosoma mansoni lipoxygenase 0.0031 0.0081 0.008
Entamoeba histolytica cysteine protease, putative 0.0445 0.1526 0.5263
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.015 0.0494 0.1212
Loa Loa (eye worm) hypothetical protein 0.015 0.0494 0.1212
Echinococcus granulosus transient receptor potential cation channel 0.0044 0.0126 0.0307
Brugia malayi jmjC domain containing protein 0.0017 0.0031 0.0077
Entamoeba histolytica cysteine proteinase, putative 0.0445 0.1526 0.5263
Trypanosoma cruzi ISWI complex protein 0.0015 0.0026 0.0026
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0153 0.2009
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0222 0.0747 0.1833
Echinococcus multilocularis lysine specific demethylase 5A 0.0063 0.0193 0.0473
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0044 0.0126 0.0125
Echinococcus granulosus hypothetical protein 0.0044 0.0126 0.0307
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0021 0.0046 0.0112
Plasmodium falciparum ataxin-2 like protein, putative 0.0012 0.0015 0.0012
Schistosoma mansoni transient receptor potential channel 0.0044 0.0126 0.0125
Onchocerca volvulus 0.0835 0.2887 1
Entamoeba histolytica cysteine protease, putative 0.0445 0.1526 0.5263
Entamoeba histolytica cysteine protease, putative 0.0179 0.0598 0.2032
Brugia malayi Ets-domain containing protein 0.0073 0.0228 0.0559
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0088 0.028 0.0788
Entamoeba histolytica cysteine protease, putative 0.0179 0.0598 0.2032
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0063 0.0193 0.0533
Schistosoma mansoni voltage-gated ion channel 0.0044 0.0126 0.0125
Loa Loa (eye worm) hypothetical protein 0.023 0.0776 0.1905
Brugia malayi hypothetical protein 0.0617 0.2126 0.5219
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0088 0.028 0.0788
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0053 0.0117
Leishmania major cathepsin L-like protease 0.0835 0.2887 1
Leishmania major DNA polymerase eta, putative 0.0021 0.0047 0.011
Onchocerca volvulus 0.0027 0.0066 0.0192
Plasmodium falciparum cGMP-dependent protein kinase 0.0089 0.0282 0.0807
Echinococcus granulosus cathepsin l1 0.0569 0.1959 0.4808
Echinococcus granulosus transient receptor potential cation channel 0.0044 0.0126 0.0307
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0044 0.0126 0.0307
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0179 0.0598 0.1466
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.057 0.1656
Entamoeba histolytica cysteine protease, putative 0.0179 0.0598 0.2032
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0047 0.0078
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0044 0.0126 0.0125
Echinococcus granulosus importin subunit beta 1 0.0029 0.0072 0.0176
Schistosoma mansoni bromodomain containing protein 0.0067 0.0205 0.0205
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0104 0.0276
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0088 0.028 0.0279
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0066 0.0161
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0044 0.0126 0.0384
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0023 0.0054
Schistosoma mansoni jumonji domain containing protein 0.0063 0.0193 0.0193
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0248 0.4235
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0088 0.028 0.0755
Plasmodium vivax hypothetical protein, conserved 0.015 0.0494 0.1437
Plasmodium vivax ataxin-2 like protein, putative 0.0012 0.0015 0.0012
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0021 0.0046 0.0112
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0012 0.0014 0.0033
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0132 0.0433 0.1062
Schistosoma mansoni hypothetical protein 0.086 0.2973 0.2972
Loa Loa (eye worm) hypothetical protein 0.1175 0.4074 1
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0064 0.0119
Plasmodium falciparum plasmepsin VIII, putative 0.023 0.0776 0.2276
Schistosoma mansoni hypothetical protein 0.0021 0.0044 0.0044
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0088 0.028 0.0279
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0088 0.028 0.0279
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0088 0.028 0.0686
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0228 0.0558
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0104 0.0254
Schistosoma mansoni hypothetical protein 0.0011 0.0011 0.0011
Echinococcus granulosus short transient receptor potential channel 6 0.0044 0.0126 0.0307
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0624 0.2149 0.6354
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0569 0.1959 0.579
Plasmodium falciparum importin beta, putative 0.0029 0.0072 0.0181
Brugia malayi voltage-dependent calcium channel 0.0044 0.0126 0.0308
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0031 0.0031
Trichomonas vaginalis adenylate cyclase type, putative 0.0063 0.0193 0.0533
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Schistosoma mansoni kinase 0.0104 0.0334 0.0334
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0069
Plasmodium falciparum serine repeat antigen 1 0.0179 0.0598 0.1745
Loa Loa (eye worm) ets-domain-containing protein 0.0011 0.0009 0.0022
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0044 0.0126 0.0308
Brugia malayi Cathepsin L-like precursor 0.0835 0.2887 0.7086
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0104 0.0254
Schistosoma mansoni transient receptor potential channel 4 0.0044 0.0126 0.0125
Loa Loa (eye worm) ctsf protein 0.0835 0.2887 0.7086
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.0482 0.0481
Echinococcus granulosus beta LACTamase domain containing family member 0.015 0.0494 0.1212
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0103
Echinococcus granulosus dna polymerase eta 0.0021 0.0047 0.0114
Brugia malayi TAR-binding protein 0.0031 0.008 0.0197
Loa Loa (eye worm) cysteine protease 0.0835 0.2887 0.7086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0835 0.2887 0.8553
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0132 0.0433 0.1062
Echinococcus multilocularis hyperpolarization activated cyclic 0.0132 0.0433 0.1062
Loa Loa (eye worm) D-ets-2 protein 0.0011 0.0009 0.0022
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0128 0.0336
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0179 0.0598 0.0597
Echinococcus granulosus voltage gated potassium channel 0.0193 0.0647 0.1588
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.0033
Toxoplasma gondii cathepsin CPL 0.0835 0.2887 0.8552
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2887 0.8553
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0049 0.0143 0.035
Leishmania major cysteine peptidase A (CPA) 0.0835 0.2887 1
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0883 0.2588
Echinococcus multilocularis ETS transcription factor Elf 5 0.0011 0.0009 0.0022
Schistosoma mansoni hypothetical protein 0.0061 0.0186 0.0186
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0184 0.0503
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0088 0.028 0.0652
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0083 0.0203
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2887 0.8553
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0883 0.2588
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0143 0.0142
Trypanosoma cruzi cruzipain precursor, putative 0.0835 0.2887 0.7075
Echinococcus granulosus lamin dm0 0.0027 0.0066 0.0161
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.047 0.1337
Echinococcus multilocularis protein C ets 2 0.0011 0.0009 0.0022
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.023 0.0776 0.0776
Echinococcus granulosus cathepsin L cysteine proteinase 0.0835 0.2887 0.7086
Giardia lamblia Fructose-bisphosphate aldolase 0.0292 0.0992 0.5858
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0179 0.0598 0.1738
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0179 0.0598 0.1745
Onchocerca volvulus 0.0835 0.2887 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0835 0.2887 1
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0088 0.028 0.0686
Onchocerca volvulus 0.0835 0.2887 1
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.0685 0.1996
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0088 0.028 0.153
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0047 0.0115
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0012 0.0014 0.0013
Brugia malayi jmjC domain containing protein 0.0063 0.0193 0.0474
Echinococcus multilocularis snurportin 1 0.0305 0.1037 0.2544
Echinococcus granulosus potassium voltage gated channel protein 0.0044 0.0126 0.0307
Plasmodium falciparum serine repeat antigen 3 0.0179 0.0598 0.1745
Brugia malayi Ets-domain containing protein 0.0011 0.0009 0.0023
Loa Loa (eye worm) hypothetical protein 0.0266 0.09 0.2209
Echinococcus granulosus transient receptor potential cation channel 0.0044 0.0126 0.0307
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0248 0.2414
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0017 0.0033 0.0032
Entamoeba histolytica cysteine protease, putative 0.0445 0.1526 0.5263
Loa Loa (eye worm) hypothetical protein 0.0027 0.0066 0.0161
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0204 0.0685 0.2331
Trypanosoma cruzi cysteine protease, putative 0.0445 0.1526 0.3722
Onchocerca volvulus 0.0012 0.0014 0.001
Schistosoma mansoni voltage-gated potassium channel 0.0105 0.034 0.0339
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Echinococcus multilocularis cathepsin L 0.0445 0.1526 0.3744
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0044 0.0126 0.0308
Loa Loa (eye worm) hypothetical protein 0.0835 0.2887 0.7086
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0975 0.3373 0.3373
Loa Loa (eye worm) hypothetical protein 0.0029 0.0072 0.0176
Leishmania major hypothetical protein, conserved 0.0088 0.028 0.0922
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0088 0.028 0.0687
Giardia lamblia Cathepsin B precursor 0.0487 0.1673 1
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0044 0.0126 0.0308
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0072 0.0169
Trypanosoma cruzi cysteine peptidase, putative 0.0445 0.1526 0.3722
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0179 0.0598 0.1738
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0386 0.0946
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0012 0.0014 0.0033
Mycobacterium tuberculosis Probable lipase LipE 0.015 0.0494 0.141
Toxoplasma gondii cathepsin CPC2 0.0179 0.0598 0.1735
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0012 0.0014 0.0033
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1175 0.4074 0.4074
Brugia malayi Transient-receptor-potential like protein 0.0044 0.0126 0.0308
Entamoeba histolytica cysteine proteinase 2 0.0445 0.1526 0.5263
Plasmodium vivax serine-repeat antigen (SERA) 0.0179 0.0598 0.1745
Trichomonas vaginalis adenylate cyclase, putative 0.0063 0.0193 0.0533
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0063 0.0193 0.0533
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0047 0.0098
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0835 0.2887 1
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0031 0.0075
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0044 0.0126 0.0307
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2887 0.8553
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0031 0.0075
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0179 0.0598 0.1745
Trichomonas vaginalis ran, putative 0.0021 0.0046 0.0095
Loa Loa (eye worm) hypothetical protein 0.0044 0.0126 0.0307
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0179 0.0598 0.1745
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0266 0.09 0.221
Onchocerca volvulus 0.0027 0.0066 0.0192
Giardia lamblia Hypothetical protein 0.0179 0.0598 0.3463
Echinococcus multilocularis transient receptor potential cation channel 0.0044 0.0126 0.0307
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Schistosoma mansoni cathepsin F (C01 family) 0.0835 0.2887 0.2887
Brugia malayi cation channel family protein 0.0044 0.0126 0.0308
Schistosoma mansoni hypothetical protein 0.0015 0.0026 0.0025
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0047 0.0046
Plasmodium vivax unspecified product 0.0266 0.09 0.2645
Trypanosoma cruzi cAMP response protein 1 0.0088 0.028 0.0652
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0047 0.0078
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0044 0.0126 0.0307
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.023 0.0776 0.0776
Schistosoma mansoni hypothetical protein 0.0036 0.0098 0.0098
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0835 0.2887 0.7086
Echinococcus multilocularis cysteine protease 0.0835 0.2887 0.7086
Brugia malayi Papain family cysteine protease containing protein 0.0835 0.2887 0.7086
Loa Loa (eye worm) TK/ROR protein kinase 0.0026 0.0064 0.0155
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0883 0.2588
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0075
Trichomonas vaginalis D-aminoacylase, putative 0.015 0.0494 0.143
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0026
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0044 0.0126 0.0307
Giardia lamblia Cysteine protease 0.0179 0.0598 0.3463
Trypanosoma cruzi cAMP response protein 1, putative 0.0088 0.028 0.0652
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0992 0.2911
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0386 0.0946
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Schistosoma mansoni tar DNA-binding protein 0.0031 0.008 0.008
Trichomonas vaginalis hypothetical protein 0.0061 0.0186 0.0513
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0047 0.0098
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0184 0.0451
Trypanosoma cruzi cysteine peptidase, putative 0.0266 0.09 0.2181
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0132 0.0433 0.0433
Onchocerca volvulus Cathepsin L homolog 0.0835 0.2887 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0184 0.0588
Schistosoma mansoni voltage-gated potassium channel 0.0729 0.2516 0.2516
Giardia lamblia DINP protein human, muc B family 0.0021 0.0047 0.0112
Mycobacterium tuberculosis Conserved hypothetical protein 0.0088 0.028 0.0755
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0835 0.2887 0.8553
Trichomonas vaginalis adenylate cyclase, putative 0.0063 0.0193 0.0533
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0487 0.1673 0.4939
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.057 0.1656
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0012 0.0014 0.0034
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0088 0.028 0.0652
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0031 0.008 0.0195
Brugia malayi beta-lactamase 0.015 0.0494 0.1213
Leishmania major GTP-binding protein, putative 0.0021 0.0046 0.0106
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0128 0.0313
Trypanosoma brucei Flagellar Member 6 0.0088 0.028 0.0922
Plasmodium vivax plasmepsin V, putative 0.023 0.0776 0.2276
Brugia malayi MH1 domain containing protein 0.0008 0 0.0001
Echinococcus granulosus potassium voltage gated channel protein 0.0044 0.0126 0.0307
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0248 1
Echinococcus multilocularis conserved hypothetical protein 0.0044 0.0126 0.0307
Loa Loa (eye worm) hypothetical protein 0.0088 0.028 0.0686
Mycobacterium ulcerans hypothetical protein 0.0088 0.028 0.2769
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0088 0.028 0.0755
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0031 0.006
Brugia malayi cathepsin F-like cysteine proteinase 0.0179 0.0598 0.1467
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0072 0.0198
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0066 0.0163
Echinococcus multilocularis ryanodine receptor 44f 0.0044 0.0126 0.0307
Schistosoma mansoni hypothetical protein 0.0305 0.1037 0.1036
Entamoeba histolytica serine/threonine protein kinase, putative 0.0204 0.0685 0.2334
Plasmodium vivax unspecified product 0.0445 0.1526 0.4506
Plasmodium falciparum plasmepsin X 0.023 0.0776 0.2276
Echinococcus multilocularis cathepsin b 0.1175 0.4074 1
Echinococcus granulosus ryanodine receptor 44f 0.0044 0.0126 0.0307
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0835 0.2887 0.8553
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0132 0.0433 0.1062
Echinococcus granulosus microtubule associated protein 2 0.069 0.238 0.584
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0018 0.0042
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0014 0.0013
Giardia lamblia Cathepsin L precursor 0.0179 0.0598 0.3463
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0179 0.0598 0.2032
Brugia malayi cathepsin F-like cysteine proteinase 0.0266 0.09 0.221
Trichomonas vaginalis adenylate cyclase, putative 0.0063 0.0193 0.0533
Loa Loa (eye worm) voltage-gated potassium channel 0.0044 0.0126 0.0307
Echinococcus multilocularis potassium voltage gated channel protein 0.0044 0.0126 0.0307
Plasmodium falciparum serine repeat antigen 8 0.0179 0.0598 0.1745
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0012 0.0014 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0445 0.1526 0.526
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0193 0.0647 0.1588
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.023 0.0776 0.2267
Loa Loa (eye worm) aspartyl protease 6 0.023 0.0776 0.1905
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0063 0.0193 0.0533
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.015 0.0494 0.0494
Toxoplasma gondii aspartyl protease 0.023 0.0776 0.2267
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0031 0.0031
Echinococcus multilocularis beta LACTamase domain containing family member 0.015 0.0494 0.1212
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0031 0.0075
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0079 0.0248 0.0608
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0047 0.016
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0088 0.028 0.08
Schistosoma mansoni glutaminase 0.0273 0.0926 0.0926
Trichomonas vaginalis guanylate cyclase, putative 0.0063 0.0193 0.0533
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0248 0.0608
Leishmania major importin beta-1 subunit, putative 0.0023 0.0053 0.0132
Loa Loa (eye worm) fli-1 protein 0.0222 0.0748 0.1835
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.0685 0.1996
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0088 0.028 0.0279
Onchocerca volvulus 0.0835 0.2887 1
Leishmania major cathepsin L-like protease 0.0835 0.2887 1
Schistosoma mansoni tar DNA-binding protein 0.0031 0.008 0.008
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0179 0.0598 0.0597
Plasmodium vivax aspartyl protease, putative 0.023 0.0776 0.2276
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0063 0.0193 0.0533
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0063 0.0193 0.0533
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0104 0.0313
Mycobacterium leprae Possible transporter protein 0.0061 0.0186 0.2786
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0016 0.0028 0.0068

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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