Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0075 | 0.1838 | 0.0925 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.8318 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.2995 | 0.2565 |
Loa Loa (eye worm) | TAR-binding protein | 0.0198 | 0.8318 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0198 | 0.8318 | 0.9749 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0097 | 0.2995 | 0.2501 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0202 | 0.8502 | 1 |
Brugia malayi | TAR-binding protein | 0.0198 | 0.8318 | 0.9783 |
Brugia malayi | Heterochromatin protein 1 | 0.0071 | 0.1622 | 0.1907 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0572 | 0.0673 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0075 | 0.1838 | 0.0925 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0157 | 0.0969 |
Giardia lamblia | PHD finger protein 15 | 0.0062 | 0.1159 | 0.5 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.1622 | 0.0647 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0198 | 0.8318 | 1 |
Plasmodium falciparum | phd finger protein, putative | 0.0062 | 0.1159 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.8318 | 1 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.1622 | 0.0647 |
Plasmodium vivax | hypothetical protein, conserved | 0.0062 | 0.1159 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0097 | 0.2995 | 0.3523 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.1622 | 0.063 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0062 | 0.1159 | 0.1393 |
Echinococcus granulosus | tar DNA binding protein | 0.0198 | 0.8318 | 0.9749 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.8318 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.8318 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.8318 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.1622 | 0.063 |
Loa Loa (eye worm) | RNA binding protein | 0.0198 | 0.8318 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.1159 | 0.1393 |
Onchocerca volvulus | Alhambra homolog | 0.0062 | 0.1159 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0157 | 0.0969 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.1622 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0202 | 0.8502 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0062 | 0.1159 | 0.1363 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.1622 | 0.063 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0198 | 0.8318 | 0.9783 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0097 | 0.2995 | 0.2501 |
Brugia malayi | jmjC domain containing protein | 0.0075 | 0.1838 | 0.2162 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0075 | 0.1838 | 0.221 |
Echinococcus granulosus | jumonji domain containing protein | 0.0086 | 0.2423 | 0.1721 |
Brugia malayi | PHD-finger family protein | 0.0062 | 0.1159 | 0.1363 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0097 | 0.2995 | 0.2501 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.3465 | 0.4165 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0097 | 0.2995 | 0.2501 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0075 | 0.1838 | 0.0949 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0127 | 0.4596 | 0.5525 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0062 | 0.1159 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0572 | 0.0688 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0086 | 0.2423 | 0.1721 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0572 | 0.0688 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.2995 | 0.2565 |
Schistosoma mansoni | jumonji domain containing protein | 0.016 | 0.633 | 0.7222 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.0157 | 0.1356 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0062 | 0.1159 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0202 | 0.8502 | 1 |
Brugia malayi | RNA binding protein | 0.0198 | 0.8318 | 0.9783 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0572 | 0.0673 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0097 | 0.2995 | 0.3601 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0075 | 0.1838 | 0.0949 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.1622 | 0.063 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0071 | 0.1622 | 0.195 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.1622 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.2995 | 0.2565 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.