Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4413 | 0.5495 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0025 | 0.1195 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.1401 | 0.0234 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.1195 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0063 | 0.7374 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.1195 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4413 | 0.5495 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.4413 | 0.5956 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.4413 | 0.4733 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.4446 | 0.4769 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.0158 | 0.0114 |
Schistosoma mansoni | bromodomain containing protein | 0.0067 | 0.7988 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0995 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0025 | 0.1195 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.3712 | 0.3972 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.4413 | 0.3655 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.4413 | 0.5956 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0025 | 0.1195 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.4413 | 0.5956 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0063 | 0.7374 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0025 | 0.1195 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4413 | 0.5495 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0667 | 0.0667 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0995 | 0.1188 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0166 | 0.139 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.1195 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0995 | 0.1287 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.1195 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1195 | 0.124 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.3293 | 0.4427 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0166 | 0.5 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0019 | 0.0166 | 0.5 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.1195 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.3293 | 0.4427 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0486 | 0.0546 |
Brugia malayi | Bromodomain containing protein | 0.004 | 0.37 | 0.2845 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1195 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.4118 | 0.4413 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.9266 | 1 |
Onchocerca volvulus | 0.0025 | 0.1195 | 0.5 | |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0025 | 0.1195 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0667 | 0.0774 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.1195 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0025 | 0.1195 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.1195 | 0.5 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0019 | 0.0166 | 0.5 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.1195 | 0.5 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0486 | 0.0592 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.1195 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0025 | 0.1195 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.1195 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.1195 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.4413 | 0.5956 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1195 | 0.124 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0486 | 0.0592 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.