Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0533 | 0.1593 |
Brugia malayi | Cytochrome P450 family protein | 0.0055 | 0.2056 | 0.6145 |
Brugia malayi | RNA binding protein | 0.0073 | 0.3346 | 1 |
Echinococcus multilocularis | geminin | 0.0166 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.3346 | 0.2971 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.1636 | 0.489 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.0217 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0026 | 0 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0073 | 0.3346 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.3346 | 0.2971 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.1636 | 0.489 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1636 | 0.489 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0217 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0217 | 1 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0217 | 0.065 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0217 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.3346 | 0.2971 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0055 | 0.2056 | 0.6145 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.1636 | 0.489 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0217 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0217 | 0.065 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0217 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0217 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.3346 | 0.2971 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0217 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0073 | 0.3346 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0533 | 0.1593 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0073 | 0.3346 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0073 | 0.3346 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0073 | 0.3346 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.3346 | 0.2971 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.