Detailed information for compound 1167322

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 809.985 | Formula: C44H63N3O11
  • H donors: 7 H acceptors: 8 LogP: 8.88 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 3
  • SMILES: CCCCCCCCCCCCCCCCC(=O)N/N=C(/[C@@]1(O)C[C@H](O[C@H]2C[C@H](N)[C@@H]([C@@H](O2)C)O)c2c(C1)c(O)c1c(c2O)C(=O)c2c(C1=O)cccc2OC)\CO
  • InChi: 1S/C44H63N3O11/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-33(49)47-46-32(25-48)44(55)23-28-36(31(24-44)58-34-22-29(45)39(50)26(2)57-34)43(54)38-37(41(28)52)40(51)27-19-18-20-30(56-3)35(27)42(38)53/h18-20,26,29,31,34,39,48,50,52,54-55H,4-17,21-25,45H2,1-3H3,(H,47,49)/b46-32+/t26-,29-,31-,34-,39+,44-/m0/s1
  • InChiKey: VRWNDLFXPLCLMK-DMLVAQDSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Cytochrome P450 family protein 0.0022 0.0047 0.0054
Loa Loa (eye worm) CYP4Cod1 0.0022 0.0047 0.0033
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0633 0.5
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0047 0.0033
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0045 0.0282 0.2396
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0633 0.08
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0876 0.8766 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0254 0.0289
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0127 0.1119 0.1366
Plasmodium vivax importin-beta 2, putative 0.0057 0.0407 0.2994
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0633 0.5215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0254 0.148
Loa Loa (eye worm) hypothetical protein 0.0097 0.0818 0.0914
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0198 0.1843 0.2393
Entamoeba histolytica hypothetical protein 0.0154 0.1393 1
Schistosoma mansoni zinc finger protein 0.0064 0.0475 0.0616
Schistosoma mansoni transcription factor LCR-F1 0.0154 0.1393 0.1809
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0593 0.1736
Brugia malayi Cytochrome P450 family protein 0.0033 0.0166 0.0189
Schistosoma mansoni hypothetical protein 0.0031 0.0139 0.0181
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0678 0.067
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0143 0.0134
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0118 0.1033 0.1259
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0162 0.1482 0.4425
Echinococcus granulosus microtubule associated protein 2 0.0772 0.7702 1
Loa Loa (eye worm) beta-lactamase 0.0075 0.0593 0.0656
Trichomonas vaginalis glucosylceramidase, putative 0.0335 0.3241 0.3234
Schistosoma mansoni hypothetical protein 0.0609 0.604 0.7843
Loa Loa (eye worm) hypothetical protein 0.0075 0.0593 0.0656
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0084 0.0678 0.067
Brugia malayi Bromodomain containing protein 0.0159 0.1451 0.1655
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0134 0.0153
Echinococcus granulosus geminin 0.0707 0.7039 0.9138
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.051 0.5031 0.5729
Trypanosoma brucei cytochrome P450, putative 0.0022 0.0047 0.0088
Trichomonas vaginalis sucrase-isomaltase, putative 0.0084 0.0678 0.067
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.0062 0.008
Echinococcus multilocularis chromobox protein 1 0.0073 0.057 0.0684
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0048 0.0318 0.0904
Trypanosoma cruzi metacaspase 5, putative 0.0045 0.0282 0.0797
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0018 0.0021
Brugia malayi Heterochromatin protein 1 0.0073 0.057 0.065
Loa Loa (eye worm) hypothetical protein 0.0099 0.0832 0.093
Trichomonas vaginalis set domain proteins, putative 0.0997 1 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0593 0.0584
Trichomonas vaginalis ran, putative 0.0042 0.0254 0.0245
Brugia malayi hypothetical protein 0.0086 0.0708 0.0807
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0382 0.0416
Loa Loa (eye worm) peptidase family M48 containing protein 0.0071 0.055 0.0608
Loa Loa (eye worm) hypothetical protein 0.0052 0.0355 0.0385
Mycobacterium tuberculosis Conserved protein 0.0075 0.0593 0.1219
Echinococcus granulosus importin subunit beta 1 0.0057 0.0407 0.0506
Trypanosoma cruzi metacaspase 5, putative 0.0045 0.0282 0.0797
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.057 0.063
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0382 0.0473
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0098 0.0826 0.1714
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0109 0.0937 0.1951
Echinococcus multilocularis dnaJ subfamily B 0.0428 0.4195 0.5184
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0139 0.0159
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0063 0.0058
Echinococcus multilocularis thioredoxin glutathione reductase 0.0044 0.027 0.0312
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0254 0.0269
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0162 0.1482 0.4425
Echinococcus multilocularis caspase 2 0.0086 0.0708 0.0855
Schistosoma mansoni hypothetical protein 0.0031 0.0139 0.0181
Brugia malayi PHD-finger family protein 0.0107 0.0917 0.1045
Echinococcus multilocularis lysosomal alpha glucosidase 0.0376 0.3668 0.453
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0081 0.0072
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0633 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0019 0.0019 0.0001
Brugia malayi Trypsin family protein 0.0099 0.0832 0.0949
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0633 0.5585
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0055 0.0046
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0023 0.0062 0.0057
Trichomonas vaginalis glucosylceramidase, putative 0.051 0.5031 0.5026
Echinococcus granulosus caax prenyl protease 1 0.0071 0.055 0.0692
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0254 0.0292
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0593 0.1736
Schistosoma mansoni cpg binding protein 0.0069 0.0531 0.069
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0018 0.0024
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0633 1
Giardia lamblia DINP protein human, muc B family 0.0019 0.0018 0.0003
Loa Loa (eye worm) hypothetical protein 0.016 0.1454 0.1641
Leishmania major GTP-binding protein, putative 0.0042 0.0254 0.0711
Loa Loa (eye worm) hypothetical protein 0.0075 0.0593 0.0656
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0678 0.067
Schistosoma mansoni hypothetical protein 0.0154 0.1393 0.1809
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0282 0.0273
Trichomonas vaginalis Clan MA, family M48, Ste24 endopeptidase-like metallopeptidase 0.0071 0.055 0.0542
Mycobacterium tuberculosis Probable dehydrogenase 0.0098 0.0826 0.1714
Trichomonas vaginalis glucosylceramidase, putative 0.0335 0.3241 0.3234
Brugia malayi beta-lactamase family protein 0.0075 0.0593 0.0676
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0081 0.0072
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0075 0.0593 0.0656
Trichomonas vaginalis glucosylceramidase, putative 0.051 0.5031 0.5026
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0282 0.0273
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0242 0.0242
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0127 0.1119 0.1453
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0031 0.0143 0.0143
Trypanosoma brucei ISWI complex protein 0.0064 0.0475 0.1379
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0593 0.0584
Echinococcus multilocularis caspase 0.0118 0.1033 0.1259
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0091 0.0103
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0609 0.604 0.6884
Brugia malayi Cell death protein 3 precursor 0.0086 0.0708 0.0807
Plasmodium falciparum glutathione reductase 0.0043 0.0264 0.3028
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0023 0.0062 0.0054
Trichomonas vaginalis glucosylceramidase, putative 0.0335 0.3241 0.3234
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0084 0.0678 0.0754
Trypanosoma cruzi hypothetical protein, conserved 0.0084 0.0678 0.1994
Plasmodium falciparum importin beta, putative 0.0057 0.0407 0.5741
Mycobacterium ulcerans beta-lactamase 0.0075 0.0593 0.1005
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0031 0.0143 0.0905
Schistosoma mansoni microtubule-associated protein tau 0.0772 0.7702 1
Schistosoma mansoni hypothetical protein 0.0066 0.0504 0.0654
Echinococcus granulosus beta LACTamase domain containing family member 0.0075 0.0593 0.0747
Brugia malayi Glycosyl hydrolases family 31 protein 0.0084 0.0678 0.0773
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0149 0.1351 0.1734
Toxoplasma gondii histone lysine methyltransferase SET1 0.0124 0.1093 0.9764
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0382 0.0436
Loa Loa (eye worm) hypothetical protein 0.0022 0.0053 0.004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0041 0.0242 0.0256
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0593 0.0769
Leishmania major importin beta-1 subunit, putative 0.0046 0.0297 0.0843
Loa Loa (eye worm) hypothetical protein 0.0198 0.1843 0.2085
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0018 0.0000090287
Brugia malayi CXXC zinc finger family protein 0.0058 0.0416 0.0475
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.0019 0.0001
Loa Loa (eye worm) thioredoxin reductase 0.0043 0.0264 0.028
Entamoeba histolytica hypothetical protein 0.0154 0.1393 1
Schistosoma mansoni DNA polymerase eta 0.0019 0.0018 0.0024
Schistosoma mansoni hypothetical protein 0.0031 0.0139 0.0181
Toxoplasma gondii CAAX metallo endopeptidase 0.0071 0.055 0.4834
Brugia malayi hypothetical protein 0.0042 0.0251 0.0286
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0048 0.0318 0.0904
Trypanosoma cruzi metacaspase, putative 0.0045 0.0282 0.0797
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0297 0.0288
Echinococcus granulosus fetal alzheimer antigen falz 0.0097 0.0816 0.1038
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0593 0.1736
Schistosoma mansoni chromobox protein 0.0073 0.057 0.0739
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0355 0.3012
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.1126 0.1462
Trypanosoma brucei glycosyl hydrolase-like protein 0.0031 0.0143 0.0376
Brugia malayi hypothetical protein 0.0033 0.0167 0.0191
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0121 0.1059 0.1354
Schistosoma mansoni cpg binding protein 0.0069 0.0531 0.069
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0343 0.3327 1
Plasmodium vivax thioredoxin reductase, putative 0.0043 0.0264 0.1579
Echinococcus granulosus histone lysine methyltransferase setb 0.0198 0.1843 0.2374
Schistosoma mansoni methyl-cpg binding protein mbd 0.0071 0.0549 0.0713
Brugia malayi hypothetical protein 0.0154 0.1393 0.159
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0084 0.0678 0.4797
Trichomonas vaginalis chromobox protein, putative 0.0073 0.057 0.0561
Loa Loa (eye worm) hypothetical protein 0.0169 0.1555 0.1756
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.1021 0.1146
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0143 0.0134
Loa Loa (eye worm) glutaminase 2 0.0579 0.5732 0.6532
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0633 0.1075
Echinococcus granulosus apoptotic protease activating factor 1 0.0042 0.0251 0.0302
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0343 0.3327 1
Echinococcus multilocularis GPCR, family 2 0.0031 0.0139 0.015
Echinococcus multilocularis zinc finger protein 0.0085 0.069 0.0834
Plasmodium vivax metacaspase 1, putative 0.0045 0.0282 0.1759
Loa Loa (eye worm) hypothetical protein 0.0031 0.0143 0.0142
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0000090287
Brugia malayi glutaminase DH11.1 0.0579 0.5732 0.6539
Echinococcus multilocularis snurportin 1 0.0609 0.604 0.7474
Brugia malayi beta-lactamase 0.0075 0.0593 0.0676
Leishmania major metacaspase, putative 0.0045 0.0282 0.0797
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0018 0.0021
Schistosoma mansoni farnesylated-protein converting enzyme 1 (M48 family) 0.0071 0.055 0.0714
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Schistosoma mansoni methyl-cpg binding protein mbd 0.0071 0.0549 0.0713
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0149 0.1351 0.1654
Schistosoma mansoni ran 0.0042 0.0254 0.0329
Trypanosoma cruzi metallo- peptidase, Clan M- Family M48 0.0071 0.055 0.1608
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0045 0.0282 0.0366
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0355 0.0417
Echinococcus multilocularis chromobox protein 1 0.0073 0.057 0.0684
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0297 0.0843
Trypanosoma brucei metacaspase MCA3 0.0045 0.0282 0.0797
Plasmodium falciparum metacaspase-like protein 0.0045 0.0282 0.3374
Schistosoma mansoni bromodomain containing protein 0.0021 0.004 0.0053
Echinococcus multilocularis lysosomal alpha glucosidase 0.0376 0.3668 0.453
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0355 0.1017
Echinococcus granulosus caspase 8 0.0045 0.0282 0.0343
Brugia malayi Thioredoxin reductase 0.0043 0.0264 0.0301
Brugia malayi SET domain containing protein 0.0018 0.0007 0.0008
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0098 0.0826 0.1714
Schistosoma mansoni hypothetical protein 0.0023 0.0063 0.0081
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0025
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0355 0.0714
Onchocerca volvulus 0.0075 0.0593 0.0593
Brugia malayi Probable ClpP-like protease 0.0079 0.0633 0.0722
Trichomonas vaginalis glucosylceramidase, putative 0.0353 0.3425 0.3419
Mycobacterium ulcerans hypothetical protein 0.0075 0.0593 0.1005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0198 0.1843 0.2393
Loa Loa (eye worm) glutathione reductase 0.0043 0.0264 0.028
Schistosoma mansoni chromobox protein 0.0073 0.057 0.0739
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0091 0.0656
Mycobacterium leprae Probable lipase LipE 0.0075 0.0593 0.5867
Loa Loa (eye worm) hypothetical protein 0.0099 0.0832 0.093
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0084 0.0678 0.067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0382 0.0496
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0081 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0282 0.0273
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0019 0.001
Trypanosoma cruzi metacaspase, putative 0.0045 0.0282 0.0797
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0162 0.1482 0.4425
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Onchocerca volvulus 0.0139 0.1241 0.1241
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0242 0.0234
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0382 0.0496
Brugia malayi RNA, U transporter 1 0.0162 0.1481 0.1689
Loa Loa (eye worm) hypothetical protein 0.0075 0.0593 0.0656
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.051 0.5031 0.5738
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0098 0.0826 0.1714
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Brugia malayi hypothetical protein 0.0052 0.0355 0.0405
Loa Loa (eye worm) hypothetical protein 0.0042 0.0251 0.0266
Plasmodium vivax hypothetical protein, conserved 0.0075 0.0593 0.4818
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0254 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0282 0.0273
Entamoeba histolytica Ran family GTPase 0.0042 0.0254 0.1711
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Trypanosoma brucei metacaspase 5, putative 0.0045 0.0282 0.0797
Entamoeba histolytica hypothetical protein 0.0154 0.1393 1
Loa Loa (eye worm) glutaminase 0.0579 0.5732 0.6532
Trypanosoma brucei Metacaspase-4 0.0045 0.0282 0.0797
Trichomonas vaginalis glucosylceramidase, putative 0.0335 0.3241 0.3234
Brugia malayi glutathione reductase 0.0043 0.0264 0.0301
Loa Loa (eye worm) hypothetical protein 0.0181 0.167 0.1888
Brugia malayi Pre-SET motif family protein 0.0127 0.1119 0.1276
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0075 0.0593 0.1005
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0065 0.0056
Brugia malayi Pre-SET motif family protein 0.0876 0.8766 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0143 0.0134
Echinococcus granulosus GPCR family 2 0.0031 0.0139 0.0157
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0091 0.0218
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0282 0.0273
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Schistosoma mansoni hypothetical protein 0.0042 0.0251 0.0325
Leishmania major phosphatidylinositol kinase related protein, putative 0.0019 0.0019 0.0001
Schistosoma mansoni alpha-glucosidase 0.0324 0.3133 0.4068
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0633 0.5
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.0018 0.0024
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0097 0.0818 0.0914
Schistosoma mansoni importin beta-1 0.0057 0.0407 0.0529
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0154 0.1393 0.1707
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0019 0.0025
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0031 0.0143 0.0376
Onchocerca volvulus 0.0058 0.0416 0.0416
Leishmania major glycosyl hydrolase-like protein 0.0031 0.0143 0.0376
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0139 0.1241 0.1611
Onchocerca volvulus 0.0099 0.0832 0.0832
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0593 0.0769
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0098 0.0826 0.8661
Loa Loa (eye worm) hypothetical protein 0.0075 0.0593 0.0656
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.1021 0.1146
Toxoplasma gondii HEAT repeat-containing protein 0.0057 0.0407 0.3535
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0075 0.0593 0.1219
Schistosoma mansoni hypothetical protein 0.0031 0.0139 0.0181
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0407 0.1176
Mycobacterium ulcerans lipase LipD 0.0075 0.0593 0.1005
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0121 0.0112
Echinococcus multilocularis geminin 0.0707 0.7039 0.8713
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Brugia malayi chromobox protein homolog 3 0.0041 0.0242 0.0277
Plasmodium vivax glutathione reductase, putative 0.0043 0.0264 0.1579
Mycobacterium ulcerans hypothetical protein 0.0181 0.1669 0.2889
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0282 0.0273
Mycobacterium tuberculosis Conserved hypothetical protein 0.0181 0.1669 0.3506
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0633 0.5585
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0274 0.0265
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0097 0.0818 0.0933
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0091 0.0218
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0031 0.0143 0.0376
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0678 0.067
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0633 0.5
Echinococcus multilocularis beta LACTamase domain containing family member 0.0075 0.0593 0.0713
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0282 0.1759
Trichomonas vaginalis glucosylceramidase, putative 0.051 0.5031 0.5026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0382 0.0451
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0097 0.0816 0.1059
Mycobacterium tuberculosis Probable reductase 0.0098 0.0826 0.1714
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0059 0.0425 0.123
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0045 0.0282 0.0322
Entamoeba histolytica hypothetical protein 0.0154 0.1393 1
Schistosoma mansoni hypothetical protein 0.0064 0.0475 0.0616
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0282 0.0273
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0376 0.3668 0.4172
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0097 0.0816 0.099
Schistosoma mansoni hypothetical protein 0.0428 0.4195 0.5447
Mycobacterium tuberculosis Probable oxidoreductase 0.0109 0.0937 0.1951
Trichomonas vaginalis chromobox protein, putative 0.0073 0.057 0.0561
Trichomonas vaginalis maltase-glucoamylase, putative 0.0084 0.0678 0.067
Echinococcus granulosus methyl CpG binding domain protein 2 0.0071 0.0549 0.0691
Entamoeba histolytica hypothetical protein 0.0026 0.0091 0.0525
Loa Loa (eye worm) hypothetical protein 0.0057 0.0407 0.0445
Brugia malayi Glycosyl hydrolases family 31 protein 0.0031 0.0143 0.0163
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0099 0.0832 0.108
Plasmodium vivax SET domain protein, putative 0.0127 0.1119 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0297 0.0288
Trichomonas vaginalis esterase, putative 0.0075 0.0593 0.0584
Schistosoma mansoni eyes absent homolog 0.0086 0.0708 0.0919
Mycobacterium ulcerans esterase/lipase LipP 0.0075 0.0593 0.1005
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0355 0.3057
Onchocerca volvulus 0.0042 0.0251 0.0251
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0355 0.0714
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0075 0.0593 0.1219
Trichomonas vaginalis glucosylceramidase, putative 0.051 0.5031 0.5026
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0075 0.0593 0.0676
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0139 0.015
Schistosoma mansoni ran 0.0042 0.0254 0.0329
Mycobacterium ulcerans glutaminase 0.0579 0.5732 1
Trichomonas vaginalis Clan MA, family M48, Ste24 endopeptidase-like metallopeptidase 0.0071 0.055 0.0542
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0274 0.0265
Leishmania major cytochrome p450-like protein 0.0022 0.0047 0.0088
Toxoplasma gondii hypothetical protein 0.0027 0.0103 0.0773
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0109 0.0937 0.1951
Loa Loa (eye worm) PHD-finger family protein 0.0086 0.0701 0.0781
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0091 0.0118
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0407 0.1176
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0593 0.0584
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0242 0.0234
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0139 0.0157
Brugia malayi CHD4 protein 0.0023 0.0062 0.007
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0254 0.0711
Mycobacterium leprae conserved hypothetical protein 0.0075 0.0593 0.5867
Schistosoma mansoni glutaminase 0.0579 0.5732 0.7443
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0047 0.0033
Onchocerca volvulus 0.0092 0.0766 0.0766
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0382 0.0451
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0198 0.1843 0.2264
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0019 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0143 0.0134
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0633 0.0763
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0355 0.0438
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0139 0.0157
Brugia malayi Peptidase family M48 containing protein 0.0071 0.055 0.0628
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0091 0.0082
Mycobacterium tuberculosis Probable lipase LipE 0.0075 0.0593 0.1219
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.0018 0.0024
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0355 0.4748
Schistosoma mansoni hypothetical protein 0.0707 0.7039 0.914
Onchocerca volvulus 0.0218 0.2048 0.2048
Onchocerca volvulus 0.0032 0.0152 0.0152
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0254 0.2138
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0047 0.0088
Leishmania major CAAX prenyl protease 1, putative,metallo-peptidase, Clan M-, Family M48 0.0071 0.055 0.1608
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0282 0.0273
Trichomonas vaginalis glucosylceramidase, putative 0.0335 0.3241 0.3234
Trypanosoma brucei metacaspase MCA2 0.0045 0.0282 0.0797
Trypanosoma cruzi ISWI complex protein 0.0064 0.0475 0.1379
Echinococcus multilocularis caspase 8 0.0045 0.0282 0.0327
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0019 0.0019 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0678 0.067
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0018 0.0000098023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0254 0.0711
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0084 0.0678 0.5995
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0633 0.635
Echinococcus granulosus zinc finger protein 0.0085 0.069 0.0874
Leishmania major trypanothione reductase 0.0043 0.0264 0.0742
Loa Loa (eye worm) bromodomain containing protein 0.0073 0.0575 0.0637
Trypanosoma cruzi metacaspase, putative 0.0045 0.0282 0.0797
Trichomonas vaginalis glutaminase, putative 0.0579 0.5732 0.5729
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0065 0.0056
Echinococcus multilocularis dna polymerase eta 0.0019 0.0018 0.0000098023
Echinococcus multilocularis apoptotic protease activating factor 1 0.0042 0.0251 0.0288
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0047 0.0088
Brugia malayi Bromodomain containing protein 0.0315 0.3043 0.3471
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Loa Loa (eye worm) histone methyltransferase 0.0023 0.0055 0.0042
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0139 0.015
Trypanosoma brucei metallo- peptidase, Clan M- Family M48 0.0071 0.055 0.1608
Brugia malayi Cytochrome P450 family protein 0.0022 0.0047 0.0054
Loa Loa (eye worm) hypothetical protein 0.0032 0.0152 0.0153
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0282 0.0273
Schistosoma mansoni caspase-3 (C14 family) 0.0118 0.1033 0.1341
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0018 0.0009
Echinococcus granulosus lysosomal alpha glucosidase 0.0376 0.3668 0.475
Trichomonas vaginalis glucosylceramidase, putative 0.0353 0.3425 0.3419
Echinococcus multilocularis caax prenyl protease 1 0.0071 0.055 0.066
Loa Loa (eye worm) hypothetical protein 0.0086 0.0708 0.0788
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0274 0.0274
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0081 0.0072
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0091 0.009
Loa Loa (eye worm) hypothetical protein 0.0079 0.0633 0.0702
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0055 0.0048
Plasmodium falciparum thioredoxin reductase 0.0043 0.0264 0.3028
Trypanosoma brucei glucosidase, putative 0.0084 0.0678 0.1994
Trypanosoma cruzi CAAX prenyl protease 1, putative 0.0071 0.055 0.1608
Schistosoma mansoni zinc finger protein 0.0085 0.069 0.0896
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0633 0.1075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Echinococcus multilocularis importin subunit beta 1 0.0057 0.0407 0.0483
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0091 0.0094
Trichomonas vaginalis glucosylceramidase, putative 0.0335 0.3241 0.3234
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0254 0.0711
Mycobacterium tuberculosis Possible penicillin-binding protein 0.048 0.4728 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0808 0.8076 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Trypanosoma cruzi trypanothione reductase, putative 0.0043 0.0264 0.0742
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0382 0.0473
Trypanosoma brucei metacaspase 0.0045 0.0282 0.0797
Loa Loa (eye worm) hypothetical protein 0.0294 0.2828 0.3212
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0416 0.0455
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Schistosoma mansoni cpg binding protein 0.0058 0.0416 0.0541
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0022 0.0047 0.0051
Brugia malayi Calcitonin receptor-like protein seb-1 0.0097 0.0818 0.0933
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0252 0.2394 0.2948
Echinococcus granulosus cpg binding protein 0.0069 0.0531 0.0667
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0355 0.2476
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0018 0.0001
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0254 0.2837
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0075 0.0593 0.1219
Echinococcus multilocularis microtubule associated protein 2 0.0772 0.7702 0.9536
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0678 0.067
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0343 0.3327 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0593 0.0656
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Echinococcus granulosus dnaJ subfamily B 0.0428 0.4195 0.5436
Brugia malayi beta-lactamase family protein 0.0075 0.0593 0.0676
Mycobacterium tuberculosis Probable hydrolase 0.0075 0.0593 0.1219
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0081 0.0072
Echinococcus granulosus neutral alpha glucosidase AB 0.0084 0.0678 0.0858
Echinococcus multilocularis cpg binding protein 0.0069 0.0531 0.0636
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0282 0.0273
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0282 0.0273
Mycobacterium tuberculosis Conserved protein 0.0075 0.0593 0.1219
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0018 0.0000098023
Schistosoma mansoni alpha-glucosidase 0.0324 0.3133 0.4068
Echinococcus multilocularis neutral alpha glucosidase AB 0.0084 0.0678 0.0819
Brugia malayi MH2 domain containing protein 0.0117 0.1021 0.1165
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0282 0.0273
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Mycobacterium tuberculosis Probable lipase LipD 0.0075 0.0593 0.1219
Trichomonas vaginalis glucosylceramidase, putative 0.051 0.5031 0.5026
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0143 0.0134
Mycobacterium tuberculosis Conserved protein 0.0075 0.0593 0.1219
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0098 0.0826 0.1714
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0166 0.0168
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0099 0.0832 0.108
Trichomonas vaginalis glucosylceramidase, putative 0.0335 0.3241 0.3234
Onchocerca volvulus 0.0075 0.0593 0.0593
Loa Loa (eye worm) hypothetical protein 0.0066 0.0504 0.0555
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0018 0.0021
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0048 0.0318 0.0904
Trypanosoma cruzi hypothetical protein, conserved 0.0084 0.0678 0.1994
Schistosoma mansoni hypothetical protein 0.0086 0.0701 0.091
Schistosoma mansoni caspase-7 (C14 family) 0.0086 0.0708 0.0919
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0139 0.0138
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0048 0.0318 0.0904
Plasmodium falciparum metacaspase 1 0.0045 0.0282 0.3374
Echinococcus granulosus caspase 3 0.0074 0.0576 0.0726
Toxoplasma gondii thioredoxin reductase 0.0043 0.0264 0.223
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0045 0.0282 0.2396
Echinococcus granulosus caspase 0.0118 0.1033 0.1321
Echinococcus multilocularis caspase 3 0.0074 0.0576 0.0692
Brugia malayi Importin beta-1 subunit 0.0057 0.0407 0.0465
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0355 0.1017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0382 0.0496
Brugia malayi Glycosyl hydrolases family 31 protein 0.0376 0.3668 0.4185
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0081 0.0072
Entamoeba histolytica hypothetical protein 0.0046 0.0297 0.2028
Echinococcus granulosus snurportin 1 0.0609 0.604 0.7838
Loa Loa (eye worm) hypothetical protein 0.0086 0.0708 0.0788
Trichomonas vaginalis maltase-glucoamylase, putative 0.0031 0.0143 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0121 0.0112
Loa Loa (eye worm) CHromoDomain protein family member 0.0023 0.0062 0.005
Toxoplasma gondii hypothetical protein 0.0055 0.039 0.3377
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0109 0.0937 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0593 0.0656
Entamoeba histolytica CAAX prenyl protease, putative 0.0071 0.055 0.3868
Leishmania major alpha glucosidase II subunit, putative 0.0084 0.0678 0.1994
Leishmania major hypothetical protein, conserved 0.0064 0.0475 0.1379
Loa Loa (eye worm) hypothetical protein 0.0045 0.0282 0.0301
Mycobacterium tuberculosis Probable esterase LipL 0.0075 0.0593 0.1219
Trichomonas vaginalis glucosylceramidase, putative 0.051 0.5031 0.5026
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0018 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0282 0.0273
Trypanosoma brucei trypanothione reductase 0.0043 0.0264 0.0742
Leishmania major hypothetical protein, conserved 0.0052 0.0355 0.1017
Echinococcus granulosus chromobox protein 1 0.0073 0.057 0.0717
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0254 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0018 0.0024
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0593 0.0584
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0593 0.0584
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0053 0.0106
Loa Loa (eye worm) hypothetical protein 0.0086 0.0708 0.0788
Toxoplasma gondii ABC1 family protein 0.0075 0.0593 0.5219
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0252 0.2394 0.3091
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0081 0.0072
Echinococcus granulosus thioredoxin glutathione reductase 0.0044 0.027 0.0327
Schistosoma mansoni bromodomain containing protein 0.0266 0.2546 0.3305
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0143 0.0134
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0019 0.0001
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0063 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0143 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0282 0.0273
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0071 0.0549 0.0659
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0139 0.0159
Echinococcus granulosus caspase 2 0.0086 0.0708 0.0897
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0297 0.0288
Schistosoma mansoni caspase-7 (C14 family) 0.0118 0.1033 0.1341
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0043 0.0264 0.0521
Onchocerca volvulus Cell death protein 3 homolog 0.0086 0.0708 0.0708
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0355 0.1017
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0633 0.0822
Loa Loa (eye worm) hypothetical protein 0.0031 0.0139 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0019 0.001
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0355 0.4748
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0081 0.0072
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0127 0.1119 1
Trypanosoma cruzi metacaspase, putative 0.0045 0.0282 0.0797
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0018 0.0009
Schistosoma mansoni hypothetical protein 0.0707 0.7039 0.914
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0084 0.0678 0.4797
Schistosoma mansoni alpha glucosidase 0.0084 0.0678 0.088
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0045 0.0282 0.2396
Onchocerca volvulus Glucosylceramidase homolog 0.0335 0.3241 0.3241
Brugia malayi latrophilin 2 splice variant baaae 0.0066 0.0504 0.0575
Trypanosoma cruzi ISWI complex protein 0.0064 0.0475 0.1379
Echinococcus granulosus chromobox protein 1 0.0073 0.057 0.0717
Onchocerca volvulus 0.0075 0.0593 0.0593
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0118 0.1033 0.1321
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0154 0.1393 0.179
Leishmania major hypothetical protein, conserved 0.0075 0.0593 0.1736
Leishmania major mitochondrial DNA polymerase beta 0.0343 0.3327 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0045 0.0282 0.0273

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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