Detailed information for compound 1167360

Basic information

Technical information
  • TDR Targets ID: 1167360
  • Name: N,N'-bis[6-(acridin-9-ylamino)hexyl]pentanedi amide
  • MW: 682.896 | Formula: C43H50N6O2
  • H donors: 4 H acceptors: 4 LogP: 8.51 Rotable bonds: 22
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(NCCCCCCNc1c2ccccc2nc2c1cccc2)CCCC(=O)NCCCCCCNc1c2ccccc2nc2c1cccc2
  • InChi: 1S/C43H50N6O2/c50-40(44-28-13-1-3-15-30-46-42-32-18-5-9-22-36(32)48-37-23-10-6-19-33(37)42)26-17-27-41(51)45-29-14-2-4-16-31-47-43-34-20-7-11-24-38(34)49-39-25-12-8-21-35(39)43/h5-12,18-25H,1-4,13-17,26-31H2,(H,44,50)(H,45,51)(H,46,48)(H,47,49)
  • InChiKey: XSGVJIDHKKPEFP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N,N'-bis[6-(9-acridinylamino)hexyl]pentanediamide
  • N,N'-bis[6-(acridin-9-ylamino)hexyl]glutaramide
  • 98502-84-2
  • N,N'-Bis(6-(9-acridinylamino)hexyl)pentanediamide
  • Pentanediamide, N,N'-bis(6-(9-acridinylamino)hexyl)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus methyl CpG binding domain protein 2 0.002 0.0243 0.0159
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.1128 0.1261
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.1128 0.1261
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0072 0.2242 0.2591
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0231 0.8334 1
Loa Loa (eye worm) beta-lactamase 0.0043 0.1128 0.1267
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.046 0.0457
Echinococcus multilocularis GPCR, family 2 0.0017 0.0118 0.0007
Trypanosoma brucei glucosidase, putative 0.0042 0.1096 0.9688
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.1128 0.0945
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.1098 0.1224
Loa Loa (eye worm) transcription factor SMAD2 0.0142 0.4941 0.5887
Onchocerca volvulus 0.0033 0.0749 0.0803
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0042 0.1096 0.4815
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0271 0.0227
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.7296 0.8741
Trypanosoma brucei ISWI complex protein 0.0018 0.0165 0.0783
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0203 0.0144
Loa Loa (eye worm) hypothetical protein 0.0047 0.13 0.1475
Onchocerca volvulus 0.0033 0.0764 0.0822
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0243 0.0159
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.1491 0.1789
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.1096 0.1222
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0243 0.0159
Plasmodium vivax SET domain protein, putative 0.003 0.0627 0.4581
Onchocerca volvulus 0.011 0.3688 0.435
Leishmania major hypothetical protein, conserved 0.0018 0.0165 0.0783
Loa Loa (eye worm) hypothetical protein 0.0082 0.2639 0.3097
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.019 0.6754 0.8085
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0558 0.0542
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0244 0.0194
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0118 0.0007
Onchocerca volvulus 0.0043 0.1128 0.1261
Brugia malayi beta-lactamase 0.0043 0.1128 0.1354
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0118 0.0141
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0244 0.0194
Echinococcus multilocularis cpg binding protein 0.0038 0.0922 0.0985
Plasmodium falciparum flap endonuclease 1 0.0026 0.046 0.8723
Echinococcus granulosus cpg binding protein 0.0038 0.0922 0.0985
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.1128 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.1388 0.1552
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0932 0.0997
Mycobacterium ulcerans beta-lactamase 0.0043 0.1128 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.019 0.6754 0.8104
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.046 0.0455
Echinococcus multilocularis methyl CpG binding domain protein 2 0.002 0.0243 0.0159
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.1128 0.0945
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0203 0.011
Trichomonas vaginalis set domain proteins, putative 0.0232 0.8371 1
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0626 0.0655
Entamoeba histolytica hypothetical protein 0.0038 0.0932 0.8382
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.005 0.1388 0.1552
Mycobacterium leprae Probable lipase LipE 0.0043 0.1128 0.5
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0244 0.0194
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.122 0.1372
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0231 0.8334 1
Brugia malayi MH2 domain containing protein 0.0142 0.4941 0.5928
Brugia malayi beta-lactamase family protein 0.0043 0.1128 0.1354
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.1128 0.0945
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0855 0.1026
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0498 0.3968
Trichomonas vaginalis chromobox protein, putative 0.0045 0.122 0.1372
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.011 0.0032
Brugia malayi Bromodomain containing protein 0.0045 0.1192 0.143
Schistosoma mansoni flap endonuclease-1 0.0023 0.0366 0.0309
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.1128 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0071 0.222 0.2564
Schistosoma mansoni alpha glucosidase 0.0042 0.1096 0.1196
Loa Loa (eye worm) hypothetical protein 0.0017 0.0118 0.0042
Schistosoma mansoni cpg binding protein 0.0038 0.0922 0.0985
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0203 0.1145
Echinococcus granulosus chromobox protein 1 0.0075 0.2364 0.2739
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.1128 0.1267
Brugia malayi SET domain containing protein 0.0014 0.0023 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0088 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0626 0.0655
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.1096 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0498 0.3968
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.1128 0.0945
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.1128 0.1236
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.1128 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0203 0.1145
Onchocerca volvulus 0.0042 0.1099 0.1225
Leishmania major hypothetical protein, conserved 0.0027 0.0498 0.3968
Schistosoma mansoni ap endonuclease 0.0019 0.0203 0.011
Mycobacterium tuberculosis Conserved protein 0.0043 0.1128 0.0945
Loa Loa (eye worm) hypothetical protein 0.0043 0.1128 0.1267
Entamoeba histolytica hypothetical protein 0.0038 0.0932 0.8382
Schistosoma mansoni hypothetical protein 0.0038 0.0932 0.0997
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.046 1
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.046 0.3607
Entamoeba histolytica hypothetical protein 0.0038 0.0932 0.8382
Schistosoma mansoni chromobox protein 0.0075 0.2364 0.2739
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.1098 0.1224
Schistosoma mansoni cpg binding protein 0.0033 0.0764 0.0793
Brugia malayi CXXC zinc finger family protein 0.0033 0.0764 0.0917
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0231 0.8334 1
Mycobacterium tuberculosis Conserved protein 0.0043 0.1128 0.0945
Echinococcus granulosus histone lysine methyltransferase setb 0.005 0.1388 0.1552
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0244 0.0194
Brugia malayi beta-lactamase family protein 0.0043 0.1128 0.1354
Schistosoma mansoni hypothetical protein 0.0017 0.0118 0.0007
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.1491 0.1789
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0231 0.8334 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0231 0.8334 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0203 0.1145
Loa Loa (eye worm) hypothetical protein 0.0043 0.1128 0.1267
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0203 0.0144
Loa Loa (eye worm) hypothetical protein 0.0052 0.1459 0.1667
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.1128 0.1236
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.1128 0.1236
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.1128 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.1128 0.1267
Schistosoma mansoni zinc finger protein 0.0018 0.0165 0.0064
Loa Loa (eye worm) hypothetical protein 0.0052 0.1491 0.1706
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0118 0.0007
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.1128 1
Trichomonas vaginalis chromobox protein, putative 0.0045 0.122 0.1372
Plasmodium vivax hypothetical protein, conserved 0.0043 0.1128 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.1128 0.0945
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0498 0.3188
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0042 0.1086 0.1184
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0231 0.8334 1
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.1128 0.1261
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0028 0.0561 0.0546
Schistosoma mansoni hypothetical protein 0.0017 0.0118 0.0007
Loa Loa (eye worm) hypothetical protein 0.0033 0.0749 0.0807
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0498 1
Trichomonas vaginalis esterase, putative 0.0043 0.1128 0.1261
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.2057 1
Echinococcus multilocularis flap endonuclease 1 0.0026 0.046 0.0423
Echinococcus granulosus fetal alzheimer antigen falz 0.0028 0.0561 0.0546
Brugia malayi hypothetical protein 0.0027 0.0498 0.0597
Echinococcus multilocularis lysosomal alpha glucosidase 0.019 0.6754 0.8078
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0498 0.1591
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0627 0.0626
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.1128 0.0945
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.1128 0.0945
Loa Loa (eye worm) hypothetical protein 0.0043 0.1128 0.1267
Loa Loa (eye worm) hypothetical protein 0.0043 0.1128 0.1267
Brugia malayi Glycosyl hydrolases family 31 protein 0.0042 0.1096 0.1315
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.1096 0.1222
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0042 0.1096 0.1227
Brugia malayi hypothetical protein 0.0038 0.0932 0.1118
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.1096 0.9688
Trichomonas vaginalis chromobox protein, putative 0.0075 0.2364 0.2752
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0244 0.0194
Echinococcus granulosus GPCR family 2 0.0017 0.0118 0.0007
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0203 0.1182
Trichomonas vaginalis sucrase-isomaltase, putative 0.0042 0.1096 0.1222
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0627 0.2286
Brugia malayi Pre-SET motif family protein 0.0204 0.7296 0.8754
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.1491 0.1706
Leishmania major alpha glucosidase II subunit, putative 0.0042 0.1096 0.9688
Schistosoma mansoni hypothetical protein 0.0024 0.0403 0.0354
Trichomonas vaginalis chromobox protein, putative 0.0075 0.2364 0.2752
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0231 0.8334 1
Echinococcus granulosus lysosomal alpha glucosidase 0.019 0.6754 0.8078
Echinococcus granulosus chromobox protein 1 0.0075 0.2364 0.2739
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0203 0.011
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.1128 0.1354
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.046 0.1388
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.046 0.2781
Loa Loa (eye worm) hypothetical protein 0.0036 0.0855 0.0936
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0627 0.0626
Echinococcus multilocularis chromobox protein 1 0.0075 0.2364 0.2739
Brugia malayi Glycosyl hydrolases family 31 protein 0.0016 0.0083 0.01
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.1096 0.1222
Onchocerca volvulus 0.0043 0.1128 0.1261
Toxoplasma gondii ABC1 family protein 0.0043 0.1128 0.499
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0028 0.0561 0.0546
Brugia malayi Flap endonuclease-1 0.0026 0.046 0.0552
Schistosoma mansoni hypothetical protein 0.0036 0.0855 0.0904
Echinococcus multilocularis lysosomal alpha glucosidase 0.019 0.6754 0.8078
Loa Loa (eye worm) hypothetical protein 0.0045 0.1195 0.1347
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0244 0.0194
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0203 0.5
Loa Loa (eye worm) hypothetical protein 0.005 0.1388 0.1581
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0932 0.0997
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.046 0.3607
Brugia malayi CHD4 protein 0.0016 0.0112 0.0135
Mycobacterium tuberculosis Conserved protein 0.0043 0.1128 0.0945
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.1128 0.1261
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0203 0.0243
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0231 0.8334 1
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0403 0.0388
Brugia malayi Bromodomain containing protein 0.0089 0.2903 0.3483
Brugia malayi PHD-finger family protein 0.0031 0.0667 0.08
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0203 0.1145
Loa Loa (eye worm) MH2 domain-containing protein 0.0142 0.4941 0.5887
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0231 0.8334 1
Brugia malayi Heterochromatin protein 1 0.0075 0.2364 0.2837
Mycobacterium ulcerans lipase LipD 0.0043 0.1128 1
Echinococcus granulosus zinc finger protein 0.0025 0.0429 0.0385
Brugia malayi Pre-SET motif family protein 0.003 0.0627 0.0752
Brugia malayi hypothetical protein 0.0017 0.0138 0.0165
Mycobacterium leprae conserved hypothetical protein 0.0043 0.1128 0.5
Onchocerca volvulus 0.0232 0.8371 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0042 0.1086 0.1184
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.1096 0.1222
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0244 0.0194
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.011 0.0032
Schistosoma mansoni hypothetical protein 0.0017 0.0118 0.0007
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0118 0.0007
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.2364 0.2765
Schistosoma mansoni alpha-glucosidase 0.0163 0.5742 0.6847
Trypanosoma cruzi ISWI complex protein 0.0018 0.0165 0.0783
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.1096 0.1222
Echinococcus granulosus neutral alpha glucosidase AB 0.0042 0.1096 0.1196
Echinococcus granulosus flap endonuclease 1 0.0026 0.046 0.0423
Schistosoma mansoni hypothetical protein 0.0018 0.0165 0.0064
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.1096 0.1222
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.1388 0.1552
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0118 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.1098 0.1224
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0932 0.0997
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0203 0.5
Schistosoma mansoni hypothetical protein 0.0017 0.0118 0.0007
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0071 0.222 0.2564
Entamoeba histolytica Flap nuclease, putative 0.0026 0.046 0.3724
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.0764 0.0825
Echinococcus multilocularis chromobox protein 1 0.0075 0.2364 0.2739
Brugia malayi chromobox protein homolog 3 0.0042 0.1098 0.1317
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.1096 0.1222
Trichomonas vaginalis maltase-glucoamylase, putative 0.0042 0.1096 0.1222
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0203 0.0145
Schistosoma mansoni zinc finger protein 0.0025 0.0429 0.0385
Schistosoma mansoni alpha-glucosidase 0.0163 0.5742 0.6847
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.1099 0.12
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.1096 0.9688
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0118 0.0042
Schistosoma mansoni cpg binding protein 0.0038 0.0922 0.0985
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.1128 0.1261
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.1128 0.1236
Loa Loa (eye worm) hypothetical protein 0.0043 0.1128 0.1267
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0244 0.0194
Trypanosoma cruzi ISWI complex protein 0.0018 0.0165 0.0783
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0112 0.0035
Echinococcus multilocularis neutral alpha glucosidase AB 0.0042 0.1096 0.1196
Entamoeba histolytica hypothetical protein 0.0038 0.0932 0.8382
Loa Loa (eye worm) hypothetical protein 0.0042 0.1098 0.123
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0498 0.3968
Echinococcus multilocularis zinc finger protein 0.0025 0.0429 0.0385
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.1096 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0498 0.0503
Schistosoma mansoni chromobox protein 0.0075 0.2364 0.2739
Onchocerca volvulus 0.0043 0.1128 0.1261
Leishmania major hypothetical protein, conserved 0.0043 0.1128 1
Schistosoma mansoni ap endonuclease 0.0019 0.0203 0.011
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.046 0.3607
Schistosoma mansoni bromodomain containing protein 0.0076 0.238 0.2758
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0498 1
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0118 0.0141
Mycobacterium ulcerans hypothetical protein 0.0043 0.1128 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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