Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3581 | 0.6972 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3581 | 0.6972 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.3581 | 0.3565 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.1144 | 0.2714 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0129 | 1 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.3581 | 0.6972 |
Schistosoma mansoni | chromobox protein | 0.007 | 0.4216 | 1 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.007 | 0.4216 | 0.4202 |
Brugia malayi | Heterochromatin protein 1 | 0.007 | 0.4216 | 0.4202 |
Brugia malayi | chromobox protein homolog 3 | 0.0039 | 0.1144 | 0.1122 |
Echinococcus multilocularis | chromobox protein 1 | 0.007 | 0.4216 | 1 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.3581 | 0.3565 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0298 | 0.0274 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1144 | 0.1122 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.212 | 0.2101 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3581 | 0.6972 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3581 | 0.6972 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.1442 | 0.3419 |
Echinococcus granulosus | chromobox protein 1 | 0.007 | 0.4216 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0042 | 0.1442 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.3581 | 0.3565 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.3581 | 0.3565 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.1144 | 0.2714 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3581 | 0.6972 |
Brugia malayi | RNA binding protein | 0.0064 | 0.3581 | 0.3565 |
Echinococcus granulosus | chromobox protein 1 | 0.007 | 0.4216 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.3581 | 0.6972 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.212 | 0.2101 |
Schistosoma mansoni | chromobox protein | 0.007 | 0.4216 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.1442 | 0.3419 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0129 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.3581 | 0.3565 |
Trichomonas vaginalis | chromobox protein, putative | 0.007 | 0.4216 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.007 | 0.4216 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.007 | 0.4216 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0039 | 0.1144 | 0.7399 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.