Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1197 | 0.4982 |
Echinococcus granulosus | lamin | 0.0028 | 0.2403 | 0.2403 |
Echinococcus multilocularis | musashi | 0.0028 | 0.2403 | 0.2403 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 1 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.1197 | 0.1197 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.1197 | 0.0975 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.2318 | 0.9646 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.2403 | 0.2403 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.1197 | 0.0975 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.1197 | 0.0975 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 1 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.1197 | 0.1197 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.1197 | 0.0975 |
Schistosoma mansoni | lamin | 0.0028 | 0.2403 | 0.137 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.1197 | 0.0975 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 1 | 0.5 |
Onchocerca volvulus | 0.0028 | 0.2403 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1197 | 0.4982 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1197 | 0.4982 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.1197 | 0.0975 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1197 | 0.4982 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.2403 | 1 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.2403 | 0.2211 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.1197 | 0.4982 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0247 | 0.1026 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0073 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.1197 | 0.1197 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.2403 | 0.2403 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.1197 | 0.1197 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.2403 | 0.2211 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.1197 | 0.4982 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.1197 | 0.1197 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1197 | 0.4982 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.1197 | 0.0975 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.1197 | 0.0975 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.1197 | 0.0975 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.2403 | 0.2403 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.2403 | 0.137 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.1197 | 0.1197 |
Echinococcus multilocularis | lamin | 0.0028 | 0.2403 | 0.2403 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.1197 | 0.1197 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.1197 | 0.1197 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0073 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.2403 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.1197 | 0.1197 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.1197 | 0.1197 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.1197 | 0.0975 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.1197 | 0.1197 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.1197 | 0.0975 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1197 | 0.4982 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.1197 | 0.4982 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.1197 | 0.0975 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.1197 | 0.4982 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.1197 | 0.1197 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1197 | 0.4982 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.1197 | 0.1197 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.1197 | 0.4982 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.2403 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.1197 | 0.4982 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.1197 | 0.0975 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.1197 | 0.4982 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0073 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.1197 | 0.0975 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.1197 | 0.1197 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.1197 | 0.0975 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.1197 | 0.0975 |
Schistosoma mansoni | lamin | 0.0028 | 0.2403 | 0.137 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.1197 | 0.4982 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.1197 | 0.1197 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.1197 | 0.0975 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.1197 | 0.1197 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.1197 | 0.0975 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.1197 | 0.1197 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.1197 | 0.4982 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.1197 | 0.1197 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.1197 | 0.0975 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.1197 | 0.0975 |
Onchocerca volvulus | 0.0028 | 0.2403 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0073 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.