Detailed information for compound 1167954

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 216.32 | Formula: C11H24N2O2
  • H donors: 4 H acceptors: 2 LogP: 0.13 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CC[C@H](NCCN[C@H](CO)CC)CO
  • InChi: 1S/C11H24N2O2/c1-3-5-11(9-15)13-7-6-12-10(4-2)8-14/h3,10-15H,1,4-9H2,2H3/t10-,11-/m0/s1
  • InChiKey: PKRAPQQOXDQEMS-QWRGUYRKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0017 0.0008 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0017 0.0008 0.0023
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0538 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0766 0.1426
Toxoplasma gondii hypothetical protein 0.0103 0.1387 1
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0766 0.0958
Brugia malayi RNA binding protein 0.0067 0.0811 0.2186
Echinococcus granulosus histone acetyltransferase MYST2 0.006 0.0702 0.0879
Echinococcus granulosus ecdysone induced protein 78C 0.0017 0.0008 0.0011
Echinococcus multilocularis polycomb protein SCMH1 0.0053 0.0584 0.0731
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0033 0.026 0.0433
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.006 0.0702 0.0879
Brugia malayi hypothetical protein 0.0238 0.357 0.9623
Toxoplasma gondii cytochrome p450 superfamily protein 0.0033 0.026 0.1639
Trypanosoma cruzi peptidase, putative 0.0024 0.0126 0.0088
Echinococcus multilocularis 0.0033 0.026 0.0325
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0017 0.0008 0.0023
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0033 0.026 0.0433
Onchocerca volvulus 0.0053 0.0584 0.2374
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0033 0.026 0.0433
Trypanosoma brucei DNA polymerase beta thumb, putative 0.009 0.1175 0.1141
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0766 0.1426
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0301 0.4591 0.457
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0811 0.2186
Echinococcus multilocularis ecdysone induced protein 78C 0.0017 0.0008 0.0011
Trypanosoma brucei cytochrome P450, putative 0.0042 0.0402 0.0365
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0474 0.0592
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0017 0.0008 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0008 0.0023
Echinococcus multilocularis thyroid hormone receptor alpha 0.0017 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0036 0.0312 0.0841
Trypanosoma cruzi peptidase, putative 0.0024 0.0126 0.0088
Schistosoma mansoni insulysin unit 3 (M16 family) 0.0024 0.0126 0.0158
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0033 0.026 0.0222
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0017 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0238 0.357 0.9623
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0909 0.1137
Echinococcus granulosus FTZ F1 alpha 0.0017 0.0008 0.0011
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0017 0.0008 0.0011
Echinococcus granulosus nardilysin 0.0024 0.0126 0.0158
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0017 0.0008 0.0011
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0033 0.026 0.0433
Loa Loa (eye worm) hypothetical protein 0.0053 0.0584 0.1575
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0008 0.0023
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0033 0.026 0.0222
Loa Loa (eye worm) RNA binding protein 0.0067 0.0811 0.2186
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0023
Loa Loa (eye worm) CYP4Cod1 0.0042 0.0402 0.1083
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0023
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0637 1 1
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.357 0.4465
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0538 1
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0033 0.026 0.0433
Brugia malayi steroid hormone receptor 0.0017 0.0008 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0033 0.026 0.0433
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0766 0.073
Echinococcus granulosus 3'partial|nardilysin 0.0024 0.0126 0.0158
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0017 0.0008 0.0011
Echinococcus granulosus polycomb protein SCMH1 0.0053 0.0584 0.0731
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0033 0.026 0.0222
Schistosoma mansoni retinoic acid receptor RXR 0.0017 0.0008 0.0011
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0909 0.1137
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0033 0.026 0.0433
Brugia malayi cytochrome P450 0.0033 0.026 0.07
Echinococcus multilocularis nardilysin 0.0024 0.0126 0.0158
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0514 0.1386
Brugia malayi MH2 domain containing protein 0.0126 0.1766 0.4761
Brugia malayi Steroid receptor seven-up type 2 0.0017 0.0008 0.0023
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0811 0.2186
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0039 0.5
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0033 0.026 0.0433
Brugia malayi nuclear hormone receptor 0.0017 0.0008 0.0023
Entamoeba histolytica hypothetical protein 0.0073 0.0909 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0008 0.0011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.005 0.0538 0.1451
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0033 0.026 0.0433
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0811 0.2186
Schistosoma mansoni RAR-like nuclear receptor 0.0017 0.0008 0.0011
Schistosoma mansoni myelin transcription factor 1 myt1 0.006 0.0702 0.0879
Schistosoma mansoni hypothetical protein 0.0033 0.026 0.0325
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0212 0.3155 0.3947
Echinococcus multilocularis histone acetyltransferase MYST2 0.006 0.0702 0.0879
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0033 0.026 0.0222
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0109 0.1491 0.1458
Loa Loa (eye worm) hypothetical protein 0.006 0.0702 0.1893
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0033 0.026 0.0433
Brugia malayi hypothetical protein 0.0032 0.0252 0.068
Mycobacterium tuberculosis Conserved hypothetical protein 0.0335 0.514 1
Echinococcus granulosus nuclear receptor co repressor related ncor 0.0268 0.4051 0.5067
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0033 0.026 0.0433
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0008 0.0011
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0474 0.0592
Brugia malayi TAR-binding protein 0.0067 0.0811 0.2186
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0039 0.0048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0017 0.0008 0.0023
Brugia malayi Cytochrome P450 family protein 0.0033 0.026 0.07
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0008 0.0023
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0538 0.0502
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0023
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0766 0.1426
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0033 0.026 0.0433
Leishmania major hypothetical protein, conserved 0.005 0.0538 0.0502
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0033 0.026 0.0433
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0039 0.0104
Loa Loa (eye worm) transcription factor SMAD2 0.0126 0.1766 0.4761
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0584 0.0731
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0766 0.0958
Brugia malayi ecdysteroid receptor 0.0017 0.0008 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0033 0.026 0.0433
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0008 0.0023
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0053 0.0584 0.2374
Leishmania major cytochrome p450-like protein 0.0042 0.0402 0.0365
Entamoeba histolytica hypothetical protein 0.0073 0.0909 1
Toxoplasma gondii rhoptry metalloprotease toxolysin TLN1 0.0024 0.0126 0.065
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0017 0.0008 0.0023
Entamoeba histolytica hypothetical protein 0.0073 0.0909 1
Brugia malayi mbt repeat family protein 0.0053 0.0584 0.1575
Leishmania major cytochrome p450-like protein 0.0033 0.026 0.0222
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0017 0.0008 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0017 0.0008 0.0023
Loa Loa (eye worm) steroid hormone receptor 0.0017 0.0008 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0017 0.0008 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0033 0.026 0.0433
Echinococcus granulosus geminin 0.0512 0.7995 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0017 0.0008 0.0011
Schistosoma mansoni hypothetical protein 0.0022 0.0093 0.0117
Leishmania major cytochrome p450-like protein 0.0033 0.026 0.0222
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0017 0.0008 0.0023
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0766 0.0958
Schistosoma mansoni hypothetical protein 0.0049 0.0514 0.0643
Schistosoma mansoni ap endonuclease 0.0019 0.0039 0.0048
Brugia malayi Cytochrome P450 family protein 0.0111 0.153 0.4123
Echinococcus multilocularis FTZ F1 alpha 0.0017 0.0008 0.0011
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0053 0.0584 0.0731
Echinococcus multilocularis geminin 0.0512 0.7995 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.009 0.1175 0.1141
Loa Loa (eye worm) hypothetical protein 0.0247 0.371 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0008 0.0011
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0033 0.026 0.0433
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0017 0.0008 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0811 0.1014
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0017 0.0008 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0017 0.0008 0.0023
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0033 0.026 0.0433
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0581 0.1566
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0017 0.0008 0.0011
Schistosoma mansoni ap endonuclease 0.0019 0.0039 0.0048
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0039 0.5
Schistosoma mansoni hypothetical protein 0.0325 0.498 0.6228
Brugia malayi photoreceptor-specific nuclear receptor 0.0247 0.371 1
Mycobacterium leprae Conserved hypothetical protein 0.0033 0.026 0.5
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.006 0.0702 0.0879
Toxoplasma gondii insulysin, putative 0.0023 0.0107 0.0506
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0474 0.0592
Brugia malayi Cytochrome P450 family protein 0.0042 0.0402 0.1083
Trypanosoma brucei peptidase, putative 0.0024 0.0126 0.0088
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0033 0.026 0.0433
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0474 0.0592
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0474 0.1277
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0033 0.026 0.0433
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0811 0.1014
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0033 0.026 0.0433
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0017 0.0008 0.0011
Brugia malayi hypothetical protein 0.005 0.0538 0.1451
Loa Loa (eye worm) cytochrome P450 family protein 0.0111 0.153 0.4123
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0033 0.026 0.0433
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0008 0.0023
Schistosoma mansoni insulysin unit 3 (M16 family) 0.0024 0.0126 0.0158
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0017 0.0008 0.0011
Mycobacterium leprae putative cytochrome p450 0.0033 0.026 0.5
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0033 0.026 0.0433
Schistosoma mansoni steroid hormone receptor ad4bp 0.0017 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0053 0.0581 0.1566
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0008 0.0023
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0008 0.0023
Schistosoma mansoni thyroid hormone receptor 0.0017 0.0008 0.0011
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0909 0.1137
Schistosoma mansoni hypothetical protein 0.0512 0.7995 1
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0033 0.026 0.0433
Loa Loa (eye worm) insulin-degrading enzyme 0.0024 0.0126 0.0341
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0474 0.0592
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0033 0.026 0.0433
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0811 0.1014
Onchocerca volvulus 0.0049 0.0514 0.2085
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0584 0.0731
Echinococcus multilocularis nuclear receptor co repressor related (ncor) 0.0268 0.4051 0.5067
Mycobacterium ulcerans hypothetical protein 0.0335 0.514 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0023
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0312 0.0841
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0766 0.1426
Brugia malayi Cytochrome P450 family protein 0.0042 0.0402 0.1083
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0637 1 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0042 0.0402 0.0712
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0581 0.1566
Brugia malayi insulin-degrading enzyme 0.0024 0.0126 0.0341
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0538 0.0502
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0033 0.026 0.0433
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0093 0.0117
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0033 0.026 0.0222
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0017 0.0008 0.0023
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0033 0.026 0.0433
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0093 0.0117
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0538 1
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0637 1 1
Brugia malayi mbt repeat family protein 0.0053 0.0584 0.1575
Schistosoma mansoni survival motor neuron protein 0.0049 0.0514 0.0643
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0212 0.3155 0.3947
Schistosoma mansoni coup transcription factor 0.0017 0.0008 0.0011
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0033 0.026 0.0433
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0301 0.4591 0.457
Chlamydia trachomatis insulinase family protease III 0.0024 0.0126 0.5
Loa Loa (eye worm) hypothetical protein 0.0168 0.2434 0.6561
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0033 0.026 0.0433
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0039 0.0048
Toxoplasma gondii sporozoite developmental protein 0.0024 0.0126 0.065
Leishmania major phosphoglycan beta 1,3 galactosyltransferase 5 0.0024 0.0126 0.0088
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0811 0.1014
Schistosoma mansoni nardilysin (M16 family) 0.0024 0.0126 0.0158
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0017 0.0008 0.0011
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0766 0.5394
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0033 0.026 0.0433
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.009 0.1175 0.1141
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0301 0.4591 0.457
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0033 0.026 0.0433
Schistosoma mansoni nardilysin (M16 family) 0.0024 0.0126 0.0158
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0033 0.026 0.0433
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0766 0.0958
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0033 0.026 0.0433
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.009 0.1175 0.1141
Trypanosoma cruzi cytochrome P450, putative 0.0042 0.0402 0.0365
Loa Loa (eye worm) MBCTL1 0.006 0.0702 0.1893
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0033 0.026 0.0433
Schistosoma mansoni hypothetical protein 0.0512 0.7995 1
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0033 0.026 0.0433
Echinococcus granulosus insulin degrading enzyme 0.0024 0.0126 0.0158
Schistosoma mansoni thyroid hormone receptor 0.0017 0.0008 0.0011
Echinococcus granulosus cytochrome P450 2K1 0.0033 0.026 0.0325
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0017 0.0008 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0017 0.0008 0.0023
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0017 0.0008 0.0011
Echinococcus multilocularis insulin degrading enzyme 0.0024 0.0126 0.0158
Loa Loa (eye worm) cytochrome P450 0.0033 0.026 0.07
Brugia malayi nuclear receptor NHR-88 0.0017 0.0008 0.0023
Onchocerca volvulus 0.0168 0.2434 1
Echinococcus granulosus tar DNA binding protein 0.0067 0.0811 0.1014
Brugia malayi hypothetical protein 0.0073 0.0909 0.2449
Echinococcus multilocularis SAM and MBT domain containing protein 0.0053 0.0584 0.0731
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0811 0.1014
Trypanosoma cruzi cytochrome P450, putative 0.0042 0.0402 0.0365
Loa Loa (eye worm) cytochrome P450 family protein 0.0042 0.0402 0.1083
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0538 0.3706
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0008 0.0011
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0033 0.026 0.0433
Schistosoma mansoni hypothetical protein 0.0073 0.0909 0.1137
Schistosoma mansoni cytochrome P450 0.0033 0.026 0.0325
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0039 0.5
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0039 0.5
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0581 0.1566
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0474 0.1277
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0474 0.0592
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0033 0.026 0.0433
Loa Loa (eye worm) mbt repeat family protein 0.0053 0.0584 0.1575
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0039 0.0104
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0039 0.5
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0023
Brugia malayi hypothetical protein 0.0168 0.2434 0.6561
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0017 0.0008 0.0011
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.006 0.0702 0.1893
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0033 0.026 0.0433
Loa Loa (eye worm) cytochrome P450 family protein 0.0042 0.0402 0.1083
Loa Loa (eye worm) MH2 domain-containing protein 0.0126 0.1766 0.4761
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0811 0.1014
Schistosoma mansoni hypothetical protein 0.0036 0.0312 0.039
Entamoeba histolytica hypothetical protein 0.0073 0.0909 1
Echinococcus multilocularis nardilysin 0.0024 0.0126 0.0158
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0033 0.026 0.0433
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0033 0.026 0.0433
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0017 0.0008 0.0023
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0474 0.0592
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.357 0.4465
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0538 0.0502
Echinococcus granulosus SAM and MBT domain containing protein 0.0053 0.0584 0.0731
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0033 0.026 0.0433

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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