Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0007 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0113 | 0.0913 | 0.2839 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0913 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0039 | 0.0007 | 0.0025 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0039 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0143 | 0.127 | 0.3949 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.0007 | 0.0022 |
Schistosoma mansoni | thyroid hormone receptor | 0.0302 | 0.3215 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0066 | 0.0333 | 0.1156 |
Brugia malayi | jmjC domain containing protein | 0.0061 | 0.0268 | 0.0931 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.0913 | 0.2839 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0333 | 0.1036 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0039 | 0.0007 | 0.0007 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0066 | 0.0333 | 0.1153 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0113 | 0.0913 | 0.0913 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.0007 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0333 | 0.1036 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0113 | 0.0913 | 0.316 |
Echinococcus multilocularis | nuclear receptor co repressor related (ncor) | 0.0275 | 0.2889 | 0.2889 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0274 | 0.2881 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0274 | 0.2881 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0263 | 0.2741 | 0.8526 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0263 | 0.2741 | 0.2741 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0068 | 0.0237 |
Echinococcus multilocularis | GPCR, family 2 | 0.0066 | 0.0333 | 0.0333 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.0007 | 0.5 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0039 | 0.0007 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0061 | 0.0268 | 0.0834 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 0.2077 | 0.7208 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0007 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0068 | 0.0068 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0066 | 0.0333 | 0.0333 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0068 | 0.0236 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0913 | 1 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0039 | 0.0007 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0068 | 0.0212 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0068 | 0.0212 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0333 | 0.1036 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0039 | 0.0007 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0061 | 0.0268 | 0.0834 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0913 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.0007 | 0.0022 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0007 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0143 | 0.127 | 0.4407 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0066 | 0.0333 | 0.1153 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0066 | 0.0333 | 0.1156 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0068 | 0.0237 |
Loa Loa (eye worm) | inositol-1 | 0.0039 | 0.0007 | 0.0025 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0061 | 0.0268 | 0.0268 |
Brugia malayi | jmjC domain containing protein | 0.0061 | 0.0268 | 0.0931 |
Echinococcus granulosus | GPCR family 2 | 0.0066 | 0.0333 | 0.1153 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0333 | 0.1036 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0209 | 0.2077 | 0.7208 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0913 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0061 | 0.0268 | 0.0834 |
Onchocerca volvulus | 0.0039 | 0 | 0.5 | |
Echinococcus granulosus | nuclear receptor co repressor related ncor | 0.0275 | 0.2889 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0068 | 0.0068 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0061 | 0.0268 | 0.0268 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0066 | 0.0333 | 0.0333 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0068 | 0.0212 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0302 | 0.3215 | 0.3215 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0039 | 0 | 0.5 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0061 | 0.0268 | 0.0929 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0068 | 0.0236 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0039 | 0 | 0.5 |
Brugia malayi | Inositol-1 | 0.0039 | 0.0007 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.127 | 0.4407 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0209 | 0.2077 | 0.7208 |
Brugia malayi | hypothetical protein | 0.0113 | 0.0913 | 0.3168 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0209 | 0.2077 | 0.7208 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.0007 | 0.5 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0263 | 0.2741 | 0.9488 |
Schistosoma mansoni | thyroid hormone receptor | 0.0302 | 0.3215 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0066 | 0.0333 | 0.1156 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.0268 | 0.0931 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0333 | 0.1156 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0039 | 0.0007 | 0.5 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0061 | 0.0268 | 0.0929 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.