Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.9262 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0618 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1149 | 0.124 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.736 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.3258 | 0.4427 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0618 | 0.0774 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0114 | 0.0123 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.1149 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0435 | 0.0546 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0435 | 0.0592 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1149 | 0.124 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0947 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1149 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0114 | 0.0123 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.1149 | 0.5 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.1149 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.1149 | 0.5 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0114 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1149 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.4417 | 0.4769 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0947 | 0.1188 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0435 | 0.0592 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.1149 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1149 | 0.5 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.1149 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.1149 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.1149 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.1149 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.3667 | 0.2845 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0106 | 0.0114 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.1149 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.1149 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0114 | 0.5 |
Schistosoma mansoni | bromodomain containing protein | 0.0062 | 0.7978 | 1 |
Onchocerca volvulus | 0.0023 | 0.1149 | 0.5 | |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.736 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0114 | 0.0123 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.3258 | 0.4427 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.4087 | 0.4413 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0114 | 0.0123 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0947 | 0.1287 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.1149 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0114 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1149 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.3679 | 0.3972 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1149 | 1 |
Brugia malayi | PHD-finger family protein | 0.0024 | 0.1356 | 0.0234 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1149 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0114 | 0.0123 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1149 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.