Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.5809 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0292 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.2103 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 1 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.2103 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0292 | 0.139 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.5235 | 0.5092 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.2103 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.2103 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.2103 | 0.1865 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.2103 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.2103 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.2103 | 0.5 |
Onchocerca volvulus | 0.0024 | 0.2103 | 0.5 | |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.5809 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.5809 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0292 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.2103 | 0.1865 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.2103 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.2103 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.2103 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.2103 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.5809 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0292 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.5809 | 1 |
Brugia malayi | hypothetical protein | 0.0036 | 0.5809 | 0.4693 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.5809 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.5235 | 0.3967 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.2103 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.5809 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.2103 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.5809 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.2103 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.2103 | 0.1865 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.2103 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.