Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0028 | 0.0079 | 0.1067 | |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.008 | 0.0403 | 0.2213 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0024 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.023 | 0.1264 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0044 | 0.0176 | 0.0397 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0063 | 0.2166 |
Brugia malayi | Bromodomain containing protein | 0.0088 | 0.0449 | 0.2469 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0165 | 0.0926 | 0.0926 |
Brugia malayi | jmjC domain containing protein | 0.0043 | 0.017 | 0.0938 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0193 | 0.0221 |
Brugia malayi | hypothetical protein | 0.0244 | 0.1409 | 0.7752 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0021 | 0.0929 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.011 | 0.0586 | 0.0673 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0244 | 0.1409 | 0.1409 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0019 | 0.0104 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0056 | 0.0064 |
Leishmania major | hypothetical protein, conserved | 0.0052 | 0.023 | 0.7867 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0024 | 0.0128 |
Echinococcus multilocularis | chromobox protein 1 | 0.008 | 0.0403 | 0.0403 |
Echinococcus multilocularis | tumor protein p63 | 0.0334 | 0.1967 | 0.1967 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0021 | 0.0118 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0017 | 0.001 | 0.0055 |
Loa Loa (eye worm) | glutathione reductase | 0.0044 | 0.0176 | 0.0966 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0034 | 0.0114 | 0.0131 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0021 | 0.0445 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.0292 | 0.0336 |
Echinococcus multilocularis | chromobox protein 1 | 0.008 | 0.0403 | 0.0403 |
Echinococcus granulosus | geminin | 0.035 | 0.2062 | 0.2368 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0021 | 0.0445 |
Schistosoma mansoni | hypothetical protein | 0.035 | 0.2062 | 0.2368 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0079 | 0.0091 |
Schistosoma mansoni | lamin | 0.0028 | 0.0079 | 0.0091 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0052 | 0.0059 |
Schistosoma mansoni | chromobox protein | 0.008 | 0.0403 | 0.0462 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.0213 | 0.1173 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0247 | 0.1429 | 0.7863 |
Onchocerca volvulus | Alhambra homolog | 0.0034 | 0.0114 | 0.3394 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0046 | 0.0193 | 0.1059 |
Trypanosoma cruzi | ISWI complex protein | 0.0016 | 0.0008 | 0.0339 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0015 | 0 | 0.0001 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.001 | 0.0012 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0063 | 0.0349 |
Trichomonas vaginalis | chromobox protein, putative | 0.008 | 0.0403 | 0.8392 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0043 | 0.017 | 0.0196 |
Echinococcus multilocularis | peregrin | 0.0044 | 0.0176 | 0.0176 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.01 | 0.0521 | 0.1174 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0025 | 0.0063 | 0.0143 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0025 | 0.0063 | 0.0143 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0021 | 0.0048 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.031 | 0.1818 | 0.2087 |
Trypanosoma brucei | ISWI complex protein | 0.0016 | 0.0008 | 0.0339 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0079 | 0.0091 |
Brugia malayi | Smad1 | 0.0017 | 0.001 | 0.0057 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0093 | 0.048 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0017 | 0.001 | 0.0057 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0024 | 0.0052 | 0.0052 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.011 | 0.0586 | 0.0586 |
Brugia malayi | Muscleblind-like protein | 0.0165 | 0.0926 | 0.5095 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0049 | 0.0206 | 0.9509 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0043 | 0.0049 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.01 | 0.0524 | 0.2884 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0083 | 0.0418 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0072 | 0.0348 | 0.0399 |
Echinococcus multilocularis | geminin | 0.035 | 0.2062 | 0.2062 |
Echinococcus multilocularis | muscleblind protein | 0.0165 | 0.0926 | 0.0926 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.007 | 0.0335 | 0.1842 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1428 | 0.8709 | 0.8709 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0021 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0072 | 0.0348 | 0.0348 |
Schistosoma mansoni | jumonji domain containing protein | 0.0088 | 0.0447 | 0.0513 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0193 | 0.0221 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.031 | 0.1818 | 1 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0017 | 0.001 | 0.0012 |
Echinococcus granulosus | tumor protein p63 | 0.0334 | 0.1967 | 0.2259 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.031 | 0.1818 | 0.1818 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0017 | 0.001 | 0.001 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0063 | 0.0349 |
Mycobacterium tuberculosis | Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. | 0.0735 | 0.4435 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0098 | 0.0511 | 0.0586 |
Trichomonas vaginalis | chromobox protein, putative | 0.0049 | 0.0206 | 0.429 |
Brugia malayi | jmjC domain containing protein | 0.011 | 0.0586 | 0.3226 |
Loa Loa (eye worm) | Smad1 | 0.0017 | 0.001 | 0.0055 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0052 | 0.023 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.023 | 1 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0017 | 0.001 | 0.0012 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0063 | 0.0292 | 0.0336 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.0213 | 0.0245 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0292 | 0.0659 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0017 | 0.0039 |
Trypanosoma brucei | trypanothione reductase | 0.0044 | 0.0176 | 0.7646 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0374 | 0.2056 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0024 | 0.0128 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0021 | 0.0025 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0017 | 0.0039 |
Brugia malayi | MH2 domain containing protein | 0.0247 | 0.1429 | 0.7864 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0021 | 0.0048 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0043 | 0.017 | 0.0196 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0299 | 0.1749 | 0.2008 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0063 | 0.0292 | 0.6097 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0025 | 0.0063 | 0.0143 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0017 | 0.0039 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.01 | 0.0521 | 0.1174 |
Plasmodium vivax | glutathione reductase, putative | 0.0044 | 0.0176 | 0.3668 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0021 | 0.0021 |
Brugia malayi | hypothetical protein | 0.0052 | 0.023 | 0.1266 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0125 | 0.0683 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0018 | 0.0019 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0185 | 0.1014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0185 | 0.385 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0021 | 0.0731 |
Schistosoma mansoni | hypothetical protein | 0.035 | 0.2062 | 0.2368 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0046 | 0.0193 | 0.0193 |
Onchocerca volvulus | 0.0035 | 0.0125 | 0.409 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.0511 | 0.0586 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0019 | 0.0022 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0063 | 0.0143 |
Echinococcus granulosus | smad | 0.0017 | 0.001 | 0.0012 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0017 | 0.0039 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0111 | 0.0589 | 0.1329 |
Schistosoma mansoni | lamin | 0.0028 | 0.0079 | 0.0091 |
Plasmodium falciparum | thioredoxin reductase | 0.0044 | 0.0176 | 0.4213 |
Trypanosoma cruzi | ISWI complex protein | 0.0016 | 0.0008 | 0.0339 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0046 | 0.0193 | 0.0221 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0043 | 0.017 | 0.0936 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0015 | 0 | 0.0001 |
Brugia malayi | MH2 domain containing protein | 0.0017 | 0.001 | 0.0057 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0147 | 0.081 | 0.4457 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0185 | 0.385 |
Schistosoma mansoni | zinc finger protein | 0.0016 | 0.0008 | 0.0009 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0024 | 0.0128 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0044 | 0.018 | 0.018 |
Brugia malayi | CHD4 protein | 0.0015 | 0 | 0.0003 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0045 | 0.0185 | 0.8099 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0111 | 0.0589 | 0.1329 |
Brugia malayi | Bromodomain containing protein | 0.0049 | 0.0206 | 0.1134 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.023 | 0.5509 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0524 | 0.2882 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0021 | 0.0025 |
Brugia malayi | PHD-finger family protein | 0.0034 | 0.0114 | 0.0628 |
Trichomonas vaginalis | chromobox protein, putative | 0.008 | 0.0403 | 0.8392 |
Brugia malayi | Heterochromatin protein 1 | 0.008 | 0.0403 | 0.2215 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0017 | 0.001 | 0.0012 |
Giardia lamblia | PHD finger protein 15 | 0.0034 | 0.0114 | 0.2734 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0114 | 0.0131 |
Echinococcus granulosus | microtubule associated protein 2 | 0.1428 | 0.8709 | 1 |
Plasmodium falciparum | phd finger protein, putative | 0.0034 | 0.0114 | 0.2734 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0046 | 0.0193 | 0.0193 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.01 | 0.0521 | 0.1174 |
Mycobacterium ulcerans | hypothetical protein | 0.0025 | 0.0063 | 0.0143 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0093 | 0.048 | 0.0551 |
Schistosoma mansoni | bromodomain containing protein | 0.0075 | 0.0371 | 0.0426 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.001 | 0.0012 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0052 | 0.023 | 0.4796 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0104 | 0.2158 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0026 | 0.007 | 0.0382 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0041 | 0.0158 | 0.0158 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0079 | 0.0091 |
Echinococcus multilocularis | smad | 0.0017 | 0.001 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0063 | 0.0346 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0079 | 0.0434 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0021 | 0.0115 |
Echinococcus granulosus | jumonji domain containing protein | 0.0047 | 0.0195 | 0.0224 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0019 | 0.0022 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0047 | 0.0195 | 0.0195 |
Onchocerca volvulus | 0.0028 | 0.0079 | 0.1067 | |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0024 | 0.0128 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 0.1409 | 0.7751 |
Plasmodium falciparum | glutathione reductase | 0.0044 | 0.0176 | 0.4213 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0021 | 0.0512 |
Brugia malayi | chromobox protein homolog 3 | 0.0045 | 0.0185 | 0.1016 |
Onchocerca volvulus | 0.005 | 0.0213 | 1 | |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0093 | 0.048 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.008 | 0.0403 | 0.0462 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0043 | 0.0234 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.001 | 0.0012 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0021 | 0.0929 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0063 | 0.0346 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0021 | 0.0025 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0093 | 0.048 | 1 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0115 | 0.0635 |
Brugia malayi | Bromodomain containing protein | 0.0044 | 0.0176 | 0.097 |
Mycobacterium leprae | probable proteasome (alpha subunit) PrcA | 0.0735 | 0.4435 | 1 |
Mycobacterium ulcerans | proteasome PrcA | 0.0735 | 0.4435 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0063 | 0.2166 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0021 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0292 | 0.0659 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0018 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0222 | 0.1221 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0193 | 0.1057 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0079 | 0.0434 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0019 | 0.0024 | 0.0495 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0063 | 0.2166 |
Echinococcus multilocularis | zinc finger protein | 0.0029 | 0.0082 | 0.0082 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.0144 | 0.0166 |
Mycobacterium tuberculosis | Probable reductase | 0.01 | 0.0521 | 0.1174 |
Echinococcus multilocularis | GPCR, family 2 | 0.0046 | 0.0193 | 0.0193 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0292 | 0.0659 |
Toxoplasma gondii | thioredoxin reductase | 0.0044 | 0.0176 | 0.3668 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0044 | 0.0176 | 0.7646 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.0063 | 0.0143 |
Leishmania major | trypanothione reductase | 0.0044 | 0.0176 | 0.6015 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0056 | 0.0064 |
Plasmodium vivax | hypothetical protein, conserved | 0.0034 | 0.0114 | 0.2381 |
Echinococcus granulosus | muscleblind protein | 0.0165 | 0.0926 | 0.1063 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.0511 | 0.0586 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0034 | 0.0114 | 0.0626 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0247 | 0.1429 | 0.7863 |
Echinococcus granulosus | chromobox protein 1 | 0.008 | 0.0403 | 0.0462 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0083 | 0.0418 | 1 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0034 | 0.0114 | 0.0131 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0044 | 0.0176 | 0.0966 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0098 | 0.0511 | 0.0586 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.081 | 0.4455 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0025 | 0.0063 | 0.106 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0024 | 0.0054 |
Echinococcus granulosus | peregrin | 0.0044 | 0.0176 | 0.0202 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0046 | 0.0193 | 0.1059 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.0208 | 0.0239 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0019 | 0.0022 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0111 | 0.0589 | 0.1329 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0019 | 0.0022 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.0511 | 0.0586 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0021 | 0.0445 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0098 | 0.0511 | 0.0511 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0043 | 0.017 | 0.0196 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0018 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0114 | 0.0626 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0208 | 0.1143 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0019 | 0.0024 | 0.0569 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0063 | 0.0346 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.0292 | 0.0336 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0063 | 0.0349 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0044 | 0.0176 | 0.3668 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0052 | 0.023 | 0.4796 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0046 | 0.0193 | 0.1057 |
Schistosoma mansoni | zinc finger protein | 0.0029 | 0.0082 | 0.0095 |
Schistosoma mansoni | chromobox protein | 0.008 | 0.0403 | 0.0462 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1428 | 0.8709 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0019 | 0.0024 | 0.0054 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.0524 | 0.0602 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0193 | 0.0221 |
Brugia malayi | Thioredoxin reductase | 0.0044 | 0.0176 | 0.0968 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0111 | 0.0589 | 0.1203 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0093 | 0.048 | 1 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0083 | 0.0418 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0034 | 0.0114 | 0.2381 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0079 | 0.0437 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0021 | 0.0929 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0235 | 0.129 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0008 | 0.0009 |
Schistosoma mansoni | smad | 0.0017 | 0.001 | 0.0012 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0098 | 0.0511 | 0.0511 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0213 | 0.0245 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0063 | 0.0292 | 1 |
Schistosoma mansoni | Smad4 | 0.0017 | 0.001 | 0.0012 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0147 | 0.081 | 0.4455 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0017 | 0.001 | 0.0055 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0063 | 0.0143 |
Trichomonas vaginalis | chromobox protein, putative | 0.0049 | 0.0206 | 0.429 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.016 | 0.0879 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0063 | 0.0143 |
Brugia malayi | MH1 domain containing protein | 0.0017 | 0.001 | 0.0057 |
Echinococcus granulosus | zinc finger protein | 0.0029 | 0.0082 | 0.0095 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0079 | 0.0434 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0104 | 0.2158 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0034 | 0.0114 | 0.2381 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0025 | 0.0063 | 0.0143 |
Brugia malayi | MH1 domain containing protein | 0.0017 | 0.001 | 0.0057 |
Brugia malayi | glutathione reductase | 0.0044 | 0.0176 | 0.0968 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0244 | 0.1409 | 0.1618 |
Leishmania major | hypothetical protein, conserved | 0.0016 | 0.0008 | 0.0266 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.0144 | 0.0144 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.01 | 0.0521 | 0.1174 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0024 | 0.0128 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.0063 | 0.106 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0056 | 0.0056 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0044 | 0.018 | 0.0206 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0147 | 0.081 | 0.4457 |
Loa Loa (eye worm) | acetyltransferase | 0.031 | 0.1818 | 1 |
Echinococcus granulosus | lamin | 0.0028 | 0.0079 | 0.0091 |
Echinococcus granulosus | Smad4 | 0.0017 | 0.001 | 0.0012 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0021 | 0.0512 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0076 | 0.0417 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0079 | 0.0079 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0046 | 0.0193 | 0.0221 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0063 | 0.0292 | 0.0659 |
Onchocerca volvulus | 0.0049 | 0.0208 | 0.9674 | |
Echinococcus granulosus | GPCR family 2 | 0.0046 | 0.0193 | 0.0221 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0098 | 0.0511 | 0.281 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0098 | 0.0511 | 0.2808 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.01 | 0.0521 | 0.1174 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0024 | 0.0052 | 0.0059 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0063 | 0.0292 | 0.0292 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.0926 | 0.5093 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0017 | 0.001 | 0.001 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.01 | 0.0521 | 0.1046 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.023 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0025 | 0.0063 | 0.0143 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0021 | 0.0445 |
Echinococcus multilocularis | Smad4 | 0.0017 | 0.001 | 0.001 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0193 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.0926 | 0.5093 |
Brugia malayi | PHD-finger family protein | 0.0034 | 0.0118 | 0.0648 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.0063 | 0.106 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0262 | 0.1442 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.023 | 0.5509 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0093 | 0.048 | 1 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0034 | 0.0114 | 0.0114 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0018 | 0.0019 | 0.0022 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0079 | 0.0437 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.