Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0096 | 0.8599 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0012 | 0.0367 | 0.0367 |
Schistosoma mansoni | fusion | 0.0034 | 0.2564 | 0.2982 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0034 | 0.2564 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0012 | 0.0367 | 0.0367 |
Schistosoma mansoni | RNA binding protein | 0.0034 | 0.2564 | 0.2982 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.2564 | 0.2564 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.0367 | 0.0426 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.0367 | 0.0426 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0034 | 0.2564 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.2564 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.2564 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.2564 | 0.2564 |
Schistosoma mansoni | thyroid hormone receptor | 0.0012 | 0.0367 | 0.0426 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0012 | 0.0367 | 0.0426 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0012 | 0.0367 | 0.0426 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.9646 | 0.9646 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.2884 | 0.3354 |
Brugia malayi | nuclear receptor NHR-88 | 0.0012 | 0.0367 | 0.0367 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0012 | 0.0367 | 0.0367 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.2884 | 0.5 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.0034 | 0.2564 | 0.2982 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0096 | 0.8599 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0012 | 0.0367 | 0.0426 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0012 | 0.0367 | 0.0426 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0367 | 0.0367 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0096 | 0.8599 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.0367 | 0.0426 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.0034 | 0.2564 | 0.2982 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.2884 | 0.3354 |
Schistosoma mansoni | zinc finger protein | 0.0034 | 0.2564 | 0.2982 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0012 | 0.0367 | 0.0367 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0034 | 0.2564 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.0367 | 0.0426 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0012 | 0.0367 | 0.0367 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0012 | 0.0367 | 0.0367 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0012 | 0.0367 | 0.0367 |
Brugia malayi | brahma associated protein 60 kDa | 0.0096 | 0.8599 | 0.8599 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.2884 | 0.5 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0012 | 0.0367 | 0.0426 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0367 | 0.0367 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0012 | 0.0367 | 0.0367 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0367 | 0.0367 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0012 | 0.0367 | 0.0426 |
Echinococcus granulosus | ring and YY1 binding protein | 0.0034 | 0.2564 | 0.2982 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0012 | 0.0367 | 0.0367 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.0034 | 0.2564 | 0.2982 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0012 | 0.0367 | 0.0426 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0012 | 0.0367 | 0.0367 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0012 | 0.0367 | 0.0367 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.2564 | 0.2982 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.0034 | 0.2564 | 0.2982 |
Schistosoma mansoni | nuclear hormone receptor | 0.0012 | 0.0367 | 0.0426 |
Chlamydia trachomatis | SWIB complex protein | 0.0096 | 0.8599 | 0.5 |
Brugia malayi | steroid hormone receptor | 0.0012 | 0.0367 | 0.0367 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0012 | 0.0367 | 0.0367 |
Onchocerca volvulus | 0.0012 | 0.0367 | 0.0426 | |
Brugia malayi | nuclear hormone receptor | 0.0012 | 0.0367 | 0.0367 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.0367 | 0.0426 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0012 | 0.0367 | 0.0426 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.0367 | 0.0367 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0012 | 0.0367 | 0.0426 |
Schistosoma mansoni | thyroid hormone receptor | 0.0012 | 0.0367 | 0.0426 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.0367 | 0.0426 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.0367 | 0.0367 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0096 | 0.8599 | 0.5 |
Brugia malayi | YY1-associated factor 2 | 0.0034 | 0.2564 | 0.2564 |
Plasmodium vivax | hypothetical protein, conserved | 0.0096 | 0.8599 | 0.5 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0034 | 0.2564 | 0.5 |
Brugia malayi | hypothetical protein | 0.0037 | 0.2884 | 0.2884 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0012 | 0.0367 | 0.0426 |
Echinococcus granulosus | FTZ F1 alpha | 0.0012 | 0.0367 | 0.0426 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.2564 | 0.2564 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.2564 | 0.5 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0012 | 0.0367 | 0.0367 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0034 | 0.2564 | 0.2564 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.8599 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0012 | 0.0367 | 0.0367 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0012 | 0.0367 | 0.0426 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.8599 | 1 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0096 | 0.8599 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.0367 | 0.0426 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0012 | 0.0367 | 0.0426 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0034 | 0.2564 | 0.2564 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.2884 | 0.5 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0034 | 0.2564 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0012 | 0.0367 | 0.0367 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0096 | 0.8599 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.0367 | 0.0367 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0367 | 0.0367 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.2884 | 0.3354 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0096 | 0.8599 | 1 |
Onchocerca volvulus | 0.0034 | 0.2564 | 0.2982 | |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.0367 | 0.0426 |
Onchocerca volvulus | 0.0034 | 0.2564 | 0.2982 | |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0096 | 0.8599 | 0.8599 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.0034 | 0.2564 | 0.2982 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.0034 | 0.2564 | 0.2982 |
Onchocerca volvulus | 0.0034 | 0.2564 | 0.2982 | |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.8599 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0012 | 0.0367 | 0.0426 |
Onchocerca volvulus | 0.0034 | 0.2564 | 0.2982 | |
Brugia malayi | ecdysteroid receptor | 0.0012 | 0.0367 | 0.0367 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0034 | 0.2564 | 0.2564 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0012 | 0.0367 | 0.0367 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.2564 | 0.2564 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0367 | 0.0367 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0034 | 0.2564 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0034 | 0.2564 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.2564 | 0.2564 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.0034 | 0.2564 | 0.2982 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0034 | 0.2564 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0012 | 0.0367 | 0.0426 |
Schistosoma mansoni | brg-1 associated factor | 0.0096 | 0.8599 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.2884 | 0.3354 |
Onchocerca volvulus | Ubiquitin thioesterase ZRANB1 homolog | 0.0034 | 0.2564 | 0.2982 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0096 | 0.8599 | 1 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0034 | 0.2564 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.2564 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0367 | 0.0367 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0034 | 0.2564 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0012 | 0.0367 | 0.0367 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0096 | 0.8599 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0034 | 0.2564 | 0.5 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0034 | 0.2564 | 0.5 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0012 | 0.0367 | 0.0426 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.0367 | 0.0367 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0012 | 0.0367 | 0.0426 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0096 | 0.8599 | 0.8599 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0012 | 0.0367 | 0.0426 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.0367 | 0.0367 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0034 | 0.2564 | 0.2564 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.0367 | 0.0367 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0096 | 0.8599 | 0.5 |
Brugia malayi | brahma associated protein 60 kDa | 0.0096 | 0.8599 | 0.8599 |
Loa Loa (eye worm) | brahma associated protein | 0.0096 | 0.8599 | 0.8599 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0096 | 0.8599 | 0.5 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0096 | 0.8599 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0367 | 0.0367 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.2884 | 0.5 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0034 | 0.2564 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.0012 | 0.0367 | 0.0426 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.0367 | 0.0426 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.2564 | 0.5 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0034 | 0.2564 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.0367 | 0.0367 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0367 | 0.0367 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.0367 | 0.0426 |
Onchocerca volvulus | 0.0096 | 0.8599 | 1 | |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0012 | 0.0367 | 0.0426 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0012 | 0.0367 | 0.0426 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.0034 | 0.2564 | 0.2982 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0096 | 0.8599 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.