Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0712 | 0.0713 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0014 | 0 | 0.5 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0712 | 0.7346 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0014 | 0 | 0.5 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0035 | 0.0969 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.4917 | 0.4926 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.1509 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0231 | 1 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0882 | 0.5844 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0712 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0047 | 0.1509 | 1 |
Brugia malayi | hypothetical protein | 0.0121 | 0.4917 | 0.4926 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.1509 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.1509 | 0.1512 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.4917 | 0.4926 |
Echinococcus multilocularis | tar DNA binding protein | 0.0124 | 0.5082 | 0.5091 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0035 | 0.0969 | 0.6421 |
Loa Loa (eye worm) | RNA binding protein | 0.0124 | 0.5082 | 0.5091 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.1443 | 0.1445 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0969 | 0.0971 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0882 | 0.5844 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0035 | 0.0969 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0712 | 0.1401 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.1509 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1443 | 0.1445 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0047 | 0.1509 | 1 |
Brugia malayi | TAR-binding protein | 0.0124 | 0.5082 | 0.5091 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0663 | 0.0664 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0 | 0.5 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0047 | 0.1509 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0712 | 0.0713 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0124 | 0.5082 | 0.5091 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0203 | 0.871 | 0.8726 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0124 | 0.5082 | 0.5091 |
Brugia malayi | Pre-SET motif family protein | 0.0203 | 0.871 | 0.8726 |
Brugia malayi | hypothetical protein | 0.0231 | 0.9982 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1443 | 0.2839 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0969 | 0.0971 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0014 | 0 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0124 | 0.5082 | 0.5091 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.1537 | 0.1539 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0047 | 0.1509 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0121 | 0.4917 | 0.4917 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.1509 | 1 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.1509 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0882 | 0.5844 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.5082 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0047 | 0.1509 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0047 | 0.1509 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.5082 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0969 | 0.0971 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1443 | 0.2839 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.1537 | 0.3024 |
Onchocerca volvulus | 0.0047 | 0.1537 | 0.1537 | |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0712 | 0.0713 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.1443 | 0.1445 |
Brugia malayi | RNA binding protein | 0.0124 | 0.5082 | 0.5091 |
Mycobacterium ulcerans | hypothetical protein | 0.0047 | 0.1509 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0712 | 0.0713 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0047 | 0.1509 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1443 | 0.2839 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.1509 | 0.1512 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0969 | 0.0971 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0 | 0.5 |
Onchocerca volvulus | Huntingtin homolog | 0.0121 | 0.4917 | 0.4917 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0712 | 0.0713 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0047 | 0.1509 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0969 | 0.0971 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.1537 | 0.3024 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0712 | 0.1401 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 0.9982 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0124 | 0.5082 | 0.5091 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.1509 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1443 | 0.1445 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.1509 | 0.1512 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0712 | 0.1401 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0047 | 0.1509 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.5082 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0035 | 0.0969 | 0.6421 |
Onchocerca volvulus | 0.0029 | 0.0712 | 0.0712 | |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0882 | 0.5844 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.1509 | 0.1512 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.5082 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.5082 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1443 | 0.1445 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.1509 | 0.1512 |
Onchocerca volvulus | 0.0047 | 0.1509 | 0.1509 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1443 | 0.1445 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0047 | 0.1509 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0231 | 0.9982 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0231 | 0.9982 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0035 | 0.0969 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0712 | 0.1401 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.1509 | 0.1512 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0047 | 0.1509 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.