Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0041 | 0.0173 | 0.014 |
Echinococcus multilocularis | musashi | 0.0029 | 0.0096 | 0.0096 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0317 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase-like protein, putative | 0.0039 | 0.0163 | 0.0226 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0106 | 0.0258 |
Toxoplasma gondii | thioredoxin reductase | 0.0426 | 0.266 | 1 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0148 | 0.0863 | 1 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0039 | 0.0163 | 0.0279 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0148 | 0.0863 | 0.2966 |
Leishmania major | DNA polymerase eta, putative | 0.0041 | 0.0173 | 0.0264 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0061 | 0.0303 | 0.0823 |
Onchocerca volvulus | 0.0077 | 0.041 | 1 | |
Trypanosoma brucei | trypanothione reductase | 0.0426 | 0.266 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0426 | 0.266 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0137 | 0.0795 | 0.0705 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0041 | 0.0173 | 0.014 |
Schistosoma mansoni | importin beta-1 | 0.0061 | 0.0303 | 0.0209 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0041 | 0.0173 | 0.0317 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.041 | 0.3517 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0264 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0148 | 0.0863 | 0.1042 |
Trichomonas vaginalis | esterase, putative | 0.0077 | 0.041 | 0.3517 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0429 | 0.2674 | 0.2674 |
Schistosoma mansoni | sulfide quinone reductase | 0.0039 | 0.0163 | 0.0068 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0077 | 0.041 | 0.1189 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0222 | 0.0222 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0039 | 0.0163 | 0.058 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0972 | 0.6182 | 0.8958 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0972 | 0.6182 | 0.8958 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0041 | 0.0173 | 0.0015 |
Schistosoma mansoni | ran | 0.0045 | 0.0199 | 0.0104 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0029 | 0.0096 | 0.0325 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0045 | 0.0199 | 0.0366 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0041 | 0.0172 | 0.0172 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0109 | 0.061 | 0.2266 |
Schistosoma mansoni | tar DNA-binding protein | 0.0137 | 0.0795 | 0.0705 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0317 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0143 | 0.0835 | 0.2037 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0077 | 0.041 | 0.041 |
Entamoeba histolytica | thioredoxin reductase, putative | 0.0039 | 0.0163 | 0.1098 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0317 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0064 | 0.0324 | 0.0853 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0222 | 0.0127 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0972 | 0.6182 | 0.8958 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0077 | 0.041 | 0.041 |
Plasmodium vivax | glutathione reductase, putative | 0.0426 | 0.266 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0148 | 0.0863 | 0.2966 |
Schistosoma mansoni | tar DNA-binding protein | 0.0137 | 0.0795 | 0.0705 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0041 | 0.0172 | 0.0172 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0148 | 0.0863 | 0.2966 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0039 | 0.0163 | 0.0226 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.0039 | 0.0163 | 0.0226 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0045 | 0.0199 | 0.0366 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0148 | 0.0863 | 0.3004 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0039 | 0.0163 | 0.0279 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0039 | 0.0163 | 0.0399 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0148 | 0.0863 | 0.2966 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0317 |
Plasmodium vivax | importin-beta 2, putative | 0.0061 | 0.0303 | 0.0772 |
Plasmodium falciparum | thioredoxin reductase | 0.0148 | 0.0863 | 0.2966 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0303 | 0.0739 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0143 | 0.0835 | 0.2037 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0972 | 0.6182 | 0.8958 |
Echinococcus multilocularis | dna polymerase kappa | 0.0041 | 0.0173 | 0.0173 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0041 | 0.0173 | 0.0173 |
Echinococcus granulosus | dna polymerase kappa | 0.0041 | 0.0173 | 0.0173 |
Plasmodium vivax | NAD(P)H-dependent glutamate synthase, putative | 0.0039 | 0.0163 | 0.0226 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0029 | 0.0096 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0163 | 0.0399 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0039 | 0.0163 | 0.0163 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0041 | 0.0172 | 0.0172 |
Brugia malayi | intermediate filament protein | 0.0029 | 0.0096 | 0.0325 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.1081 | 0.6881 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0148 | 0.0863 | 0.2966 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0148 | 0.0863 | 0.2966 |
Brugia malayi | hypothetical protein | 0.003 | 0.0106 | 0.0362 |
Mycobacterium ulcerans | hypothetical protein | 0.0077 | 0.041 | 0.3517 |
Trypanosoma brucei | unspecified product | 0.0041 | 0.0173 | 0.0317 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0039 | 0.0163 | 0.058 |
Schistosoma mansoni | hypothetical protein | 0.065 | 0.41 | 0.4043 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0077 | 0.041 | 0.1238 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0148 | 0.0863 | 0.2966 |
Leishmania major | 2,4-dienoyl-coa reductase-like protein | 0.0039 | 0.0163 | 0.0226 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.065 | 0.41 | 1 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0039 | 0.0163 | 0.1098 |
Mycobacterium tuberculosis | Probable reductase | 0.0972 | 0.6182 | 0.8958 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0426 | 0.266 | 0.6487 |
Brugia malayi | TAR-binding protein | 0.0137 | 0.0795 | 0.2962 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.1081 | 0.6881 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0972 | 0.6182 | 0.8958 |
Loa Loa (eye worm) | RNA binding protein | 0.0137 | 0.0795 | 0.1938 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0173 | 0.0317 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0039 | 0.0163 | 0.0163 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0155 | 0.0549 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0494 | 0.3098 | 0.4369 |
Schistosoma mansoni | DNA polymerase eta | 0.0041 | 0.0173 | 0.0078 |
Echinococcus multilocularis | snurportin 1 | 0.065 | 0.41 | 0.41 |
Leishmania major | hypothetical protein, conserved | 0.0039 | 0.0163 | 0.0226 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0061 | 0.0305 | 0.2022 |
Schistosoma mansoni | tar DNA-binding protein | 0.0137 | 0.0795 | 0.0705 |
Leishmania major | hypothetical protein, conserved | 0.0039 | 0.0163 | 0.0226 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.001 | 0.0024 |
Plasmodium falciparum | importin beta, putative | 0.0061 | 0.0303 | 0.0772 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.041 | 0.3517 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0039 | 0.0163 | 0.0068 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0077 | 0.041 | 0.0317 |
Echinococcus multilocularis | tar DNA binding protein | 0.0137 | 0.0795 | 0.0795 |
Brugia malayi | beta-lactamase family protein | 0.0077 | 0.041 | 0.1508 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0077 | 0.041 | 0.0366 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0163 | 0.0068 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0039 | 0.0163 | 0.0226 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0039 | 0.0163 | 0.0163 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0264 |
Trypanosoma brucei | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0039 | 0.0163 | 0.0279 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0061 | 0.0305 | 0.0211 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0039 | 0.0163 | 0.0163 |
Leishmania major | GTP-binding protein, putative | 0.0045 | 0.0199 | 0.0366 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0148 | 0.0863 | 0.2966 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0972 | 0.6182 | 0.8958 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.041 | 0.0999 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0039 | 0.0163 | 0.0279 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0148 | 0.0863 | 0.2966 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0057 | 0.0278 | 0.0679 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0077 | 0.041 | 0.1189 |
Echinococcus granulosus | lamin | 0.0029 | 0.0096 | 0.0096 |
Entamoeba histolytica | hypothetical protein | 0.0049 | 0.0229 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0077 | 0.041 | 0.0999 |
Trypanosoma brucei | 2,4-dienoyl-coa reductase-like protein | 0.0039 | 0.0163 | 0.0279 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.041 | 0.0999 |
Brugia malayi | glutamate synthase | 0.0039 | 0.0163 | 0.058 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0041 | 0.0172 | 0.0172 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0137 | 0.0795 | 0.2962 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0064 | 0.0324 | 0.0324 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0041 | 0.0172 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0173 | 0.0422 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0148 | 0.0863 | 1 |
Echinococcus multilocularis | glutamate synthase | 0.0039 | 0.0163 | 0.0163 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0039 | 0.0163 | 0.0226 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0155 | 0.006 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0148 | 0.0863 | 1 |
Brugia malayi | hypothetical protein | 0.002 | 0.0037 | 0.0101 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0077 | 0.041 | 0.0366 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0041 | 0.0173 | 0.0015 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0077 | 0.041 | 0.0366 |
Echinococcus granulosus | glutamate synthase | 0.0039 | 0.0163 | 0.0163 |
Echinococcus granulosus | importin subunit beta 1 | 0.0061 | 0.0303 | 0.0303 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0039 | 0.0163 | 0.0163 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0039 | 0.0163 | 0.0163 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0039 | 0.0163 | 0.0163 |
Trichomonas vaginalis | ran, putative | 0.0045 | 0.0199 | 0.0514 |
Schistosoma mansoni | glutamate synthase | 0.0039 | 0.0163 | 0.0068 |
Plasmodium falciparum | thioredoxin reductase | 0.0426 | 0.266 | 1 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0064 | 0.0324 | 0.0324 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.041 | 0.0366 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0061 | 0.0305 | 0.0779 |
Schistosoma mansoni | glutamate synthase | 0.0039 | 0.0163 | 0.0068 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0039 | 0.0163 | 0.0163 |
Loa Loa (eye worm) | TAR-binding protein | 0.0137 | 0.0795 | 0.1938 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0148 | 0.0863 | 0.3004 |
Toxoplasma gondii | ABC1 family protein | 0.0077 | 0.041 | 0.1189 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0222 | 0.0127 |
Schistosoma mansoni | sulfide quinone reductase | 0.0039 | 0.0163 | 0.0068 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0049 | 0.0229 | 0.0934 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.041 | 0.0999 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0148 | 0.0863 | 0.2966 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0317 |
Entamoeba histolytica | Ran family GTPase | 0.0045 | 0.0199 | 0.5997 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1564 | 1 | 1 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0049 | 0.0229 | 0.0934 |
Toxoplasma gondii | selenide, water dikinase | 0.0039 | 0.0163 | 0.0226 |
Brugia malayi | RNA binding protein | 0.0137 | 0.0795 | 0.2962 |
Brugia malayi | MH2 domain containing protein | 0.0143 | 0.0835 | 0.3115 |
Plasmodium vivax | type II NADH:ubiquinone oxidoreductase, putative | 0.0039 | 0.0163 | 0.0226 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0077 | 0.041 | 0.3517 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0148 | 0.0863 | 1 |
Trypanosoma brucei | NADH dehydrogenase | 0.0039 | 0.0163 | 0.0279 |
Plasmodium falciparum | NAD(P)H-dependent glutamate synthase, putative | 0.0039 | 0.0163 | 0.0226 |
Leishmania major | trypanothione reductase | 0.0426 | 0.266 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0155 | 0.006 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0077 | 0.041 | 0.0999 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0148 | 0.0863 | 0.3004 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0061 | 0.0305 | 0.0211 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.041 | 0.0999 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0041 | 0.0172 | 0.0172 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0041 | 0.0173 | 0.0078 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0317 |
Leishmania major | 2,4-dienoyl-coa reductase fadh1, putative | 0.0039 | 0.0163 | 0.0226 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0077 | 0.041 | 0.0366 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.041 | 0.0366 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0041 | 0.0173 | 0.0616 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0163 | 0.0226 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0061 | 0.0303 | 0.0303 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0039 | 0.0163 | 0.0226 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0041 | 0.0172 | 0.0612 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.0039 | 0.0163 | 0.0226 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0041 | 0.0172 | 0.0124 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0045 | 0.0199 | 0.0419 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0041 | 0.0172 | 0.0124 |
Echinococcus multilocularis | lamin dm0 | 0.0029 | 0.0096 | 0.0096 |
Onchocerca volvulus | 0.0039 | 0.0163 | 0.2152 | |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0041 | 0.0173 | 0.0173 |
Mycobacterium leprae | Probable lipase LipE | 0.0077 | 0.041 | 0.0366 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0045 | 0.0199 | 0.0366 |
Brugia malayi | beta-lactamase | 0.0077 | 0.041 | 0.1508 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0077 | 0.041 | 0.0366 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.1081 | 0.6881 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.1081 | 0.6881 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0093 | 0.0226 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0173 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0096 | 0.0234 |
Echinococcus multilocularis | lamin | 0.0029 | 0.0096 | 0.0096 |
Trichomonas vaginalis | importin beta-1, putative | 0.0049 | 0.0229 | 0.0934 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0061 | 0.0305 | 0.2022 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0148 | 0.0863 | 0.0863 |
Entamoeba histolytica | NAD(FAD)-dependent dehydrogenase, putative | 0.0039 | 0.0163 | 0.1098 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0041 | 0.0172 | 0.0077 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0039 | 0.0163 | 0.0163 |
Schistosoma mansoni | glutamate synthase | 0.0039 | 0.0163 | 0.0068 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0148 | 0.0863 | 0.2966 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0041 | 0.0173 | 0.0264 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0041 | 0.0172 | 0.0077 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0429 | 0.2674 | 0.2674 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0222 | 0.0222 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0137 | 0.0795 | 0.1938 |
Treponema pallidum | NADH oxidase | 0.0148 | 0.0863 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0222 | 0.0127 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0148 | 0.0863 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0029 | 0.0096 | 0.0096 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0049 | 0.0229 | 0.0481 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0061 | 0.0305 | 0.0305 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0041 | 0.0173 | 0.014 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0426 | 0.266 | 1 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0109 | 0.061 | 0.2266 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0324 | 0.2291 |
Onchocerca volvulus | 0.0077 | 0.041 | 1 | |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0173 | 0.0317 |
Brugia malayi | Importin beta-1 subunit | 0.0061 | 0.0303 | 0.1106 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0317 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0317 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0148 | 0.0863 | 0.2966 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0045 | 0.0199 | 0.0199 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0061 | 0.0303 | 0.0823 |
Plasmodium falciparum | type II NADH:ubiquinone oxidoreductase | 0.0039 | 0.0163 | 0.0226 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0148 | 0.0863 | 1 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0041 | 0.0172 | 0.2281 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0039 | 0.0163 | 0.0163 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0148 | 0.0863 | 1 |
Plasmodium falciparum | ferrodoxin reductase-like protein | 0.0039 | 0.0163 | 0.0226 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0061 | 0.0305 | 0.1113 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0148 | 0.0863 | 0.322 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase fadh1, putative | 0.0039 | 0.0163 | 0.0226 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0317 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0064 | 0.0324 | 0.0239 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0041 | 0.0172 | 0.026 |
Mycobacterium ulcerans | beta-lactamase | 0.0077 | 0.041 | 0.3517 |
Mycobacterium tuberculosis | Conserved protein | 0.0077 | 0.041 | 0.0366 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.0324 | 0.023 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0148 | 0.0863 | 0.2966 |
Loa Loa (eye worm) | glutathione reductase | 0.0426 | 0.266 | 0.6487 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0148 | 0.0863 | 0.2966 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0222 | 0.0222 |
Plasmodium falciparum | glutathione reductase | 0.0148 | 0.0863 | 0.2966 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1564 | 1 | 1 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0045 | 0.0199 | 0.0366 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.041 | 0.0999 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0148 | 0.0863 | 0.0775 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.0324 | 0.023 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0148 | 0.0863 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.0041 | 0.0173 | 0.0173 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0148 | 0.0863 | 0.2966 |
Onchocerca volvulus | 0.0077 | 0.041 | 1 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0324 | 0.2291 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0041 | 0.0173 | 0.0264 |
Plasmodium vivax | hypothetical protein, conserved | 0.0077 | 0.041 | 0.1189 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0222 | 0.0541 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0041 | 0.0173 | 0.0422 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0077 | 0.041 | 0.3517 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0041 | 0.0173 | 0.0078 |
Mycobacterium ulcerans | lipase LipD | 0.0077 | 0.041 | 0.3517 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0039 | 0.0163 | 0.0226 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0045 | 0.0199 | 0.0715 |
Leishmania major | NADH dehydrogenase, putative | 0.0039 | 0.0163 | 0.0226 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0045 | 0.0199 | 0.0199 |
Leishmania major | importin beta-1 subunit, putative | 0.0049 | 0.0229 | 0.0481 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0317 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0061 | 0.0303 | 0.0772 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0077 | 0.041 | 0.3517 |
Leishmania major | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0264 |
Echinococcus granulosus | intermediate filament protein | 0.0029 | 0.0096 | 0.0096 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0077 | 0.041 | 0.3517 |
Schistosoma mansoni | tar DNA-binding protein | 0.0137 | 0.0795 | 0.0705 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0039 | 0.0163 | 0.1098 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0426 | 0.266 | 0.3716 |
Giardia lamblia | DINP protein human, muc B family | 0.0041 | 0.0173 | 0.014 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0039 | 0.0163 | 0.0226 |
Entamoeba histolytica | pyridine nucleotide-disulfide oxidoreductase family protein | 0.0039 | 0.0163 | 0.1098 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0039 | 0.0163 | 0.0163 |
Mycobacterium leprae | conserved hypothetical protein | 0.0077 | 0.041 | 0.0366 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0045 | 0.0199 | 0.0486 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0041 | 0.0172 | 0.0313 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0148 | 0.0863 | 0.2966 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0039 | 0.0163 | 0.1098 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0155 | 0.0155 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0148 | 0.0863 | 0.2966 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0148 | 0.0863 | 0.2966 |
Plasmodium falciparum | glutathione reductase | 0.0426 | 0.266 | 1 |
Schistosoma mansoni | ran | 0.0045 | 0.0199 | 0.0104 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0077 | 0.041 | 0.0317 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0041 | 0.0172 | 0.0124 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0041 | 0.0173 | 0.0616 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0039 | 0.0163 | 0.0163 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0041 | 0.0173 | 0.0317 |
Echinococcus granulosus | snurportin 1 | 0.065 | 0.41 | 0.41 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0045 | 0.0199 | 0.0514 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0148 | 0.0863 | 0.3004 |
Echinococcus granulosus | tar DNA binding protein | 0.0137 | 0.0795 | 0.0795 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0077 | 0.041 | 0.0366 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0045 | 0.0199 | 0.0366 |
Leishmania major | hypothetical protein, conserved | 0.0077 | 0.041 | 0.1189 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.041 | 0.0999 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0148 | 0.0863 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0041 | 0.0173 | 0.2432 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0061 | 0.0305 | 0.0305 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0172 | 0.0124 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.0324 | 0.2291 |
Brugia malayi | RNA, U transporter 1 | 0.0173 | 0.1027 | 0.3837 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0172 | 0.042 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.003 | 0.0106 | 0.0055 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0041 | 0.0172 | 0.026 |
Brugia malayi | Thioredoxin reductase | 0.0426 | 0.266 | 1 |
Plasmodium vivax | ferrodoxin reductase, putative | 0.0039 | 0.0163 | 0.0226 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0039 | 0.0163 | 0.0226 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0064 | 0.0324 | 0.0853 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0222 | 0.08 |
Loa Loa (eye worm) | intermediate filament protein | 0.0029 | 0.0096 | 0.0234 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0039 | 0.0163 | 0.0399 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0039 | 0.0163 | 0.058 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0264 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0163 | 0.0226 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0222 | 0.0222 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0041 | 0.0172 | 0.026 |
Brugia malayi | beta-lactamase family protein | 0.0077 | 0.041 | 0.1508 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0148 | 0.0863 | 0.0863 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0077 | 0.041 | 0.1508 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0155 | 0.0155 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0041 | 0.0173 | 0.0264 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0077 | 0.041 | 0.0366 |
Trypanosoma cruzi | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0039 | 0.0163 | 0.0226 |
Brugia malayi | glutathione reductase | 0.0426 | 0.266 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0041 | 0.0173 | 0.0173 |
Leishmania major | hypothetical protein, conserved | 0.0039 | 0.0163 | 0.0226 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0148 | 0.0863 | 0.2966 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0077 | 0.041 | 0.3517 |
Entamoeba histolytica | disulphide oxidoreductase, putative | 0.0039 | 0.0163 | 0.1098 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.