TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 649.736 | Formula: C30H47N7O9
H donors: 8 H acceptors: 8 LogP: -2.39 Rotable bonds: 21
Rule of 5 violations (Lipinski): 3
SMILES: CC(C[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)O)[C@H](O)C)OC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)N)Cc1ccc(cc1)O)C
InChi: 1S/C30H47N7O9/c1-16(2)14-23(27(42)37-13-5-7-22(37)26(41)36-24(17(3)38)28(43)44)46-29(45)21(15-18-8-10-19(39)11-9-18)35-25(40)20(31)6-4-12-34-30(32)33/h8-11,16-17,20-24,38-39H,4-7,12-15,31H2,1-3H3,(H,35,40)(H,36,41)(H,43,44)(H4,32,33,34)/t17-,20+,21+,22+,23+,24+/m1/s1
InChiKey: RNUOOQBPRDUMNU-UEHMALFGSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	intermediate filament protein	0.0029	0.0225	0.0452
Onchocerca volvulus		0.0031	0.0247	0.0751
Echinococcus granulosus	g protein coupled receptor	0.0023	0.0158	0.0316
Echinococcus granulosus	lamin	0.0029	0.0225	0.0452
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0116	1
Onchocerca volvulus		0.0029	0.0225	0.068
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0023	0.0158	0.0316
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0116	1
Schistosoma mansoni	hypothetical protein	0.0441	0.4989	0.6961
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0023	0.0158	0.0199
Brugia malayi	AMP-binding enzyme family protein	0.0028	0.0216	0.065
Schistosoma mansoni	amine GPCR	0.0023	0.0158	0.0199
Echinococcus granulosus	rhodopsin orphan GPCR	0.0023	0.0158	0.0316
Brugia malayi	larval opioid receptor	0.0023	0.0158	0.046
Schistosoma mansoni	biogenic amine receptor	0.0023	0.0158	0.0199
Onchocerca volvulus		0.0023	0.0158	0.046
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0028	0.0216	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0158	0.0199
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0023	0.0158	0.0507
Echinococcus multilocularis	survival motor neuron protein 1	0.0255	0.2838	0.2838
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0116	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Brugia malayi	AMP-binding enzyme family protein	0.0028	0.0216	0.065
Echinococcus multilocularis	lamin	0.0029	0.0225	0.0225
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0015	0.0049
Brugia malayi	Serotonin receptor	0.0023	0.0158	0.046
Onchocerca volvulus		0.0023	0.0158	0.046
Trypanosoma cruzi	DNA polymerase kappa, putative	0.002	0.0116	1
Echinococcus granulosus	neuropeptides capa receptor	0.0023	0.0158	0.0316
Loa Loa (eye worm)	hypothetical protein	0.002	0.0116	0.0372
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.0036	0.0311	0.0311
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0097	0.0312
Onchocerca volvulus	Huntingtin homolog	0.0278	0.3106	1
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0045	0.0146
Schistosoma mansoni	hypothetical protein	0.0023	0.0158	0.0199
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0023	0.0158	0.0158
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0011	0.0015	0.0049
Brugia malayi	hypothetical protein	0.0023	0.0158	0.046
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0011	0.0015	0.0031
Giardia lamblia	DINP protein human, muc B family	0.002	0.0116	0.5
Echinococcus granulosus	7TM GPCR rhodopsin	0.0023	0.0158	0.0316
Echinococcus granulosus	g protein coupled receptor	0.0023	0.0158	0.0316
Schistosoma mansoni	hypothetical protein	0.0016	0.0069	0.0075
Brugia malayi	G-protein coupled receptor	0.0023	0.0158	0.046
Brugia malayi	G protein-coupled receptor F59B2.13	0.0023	0.0158	0.046
Brugia malayi	cytoplasmic intermediate filament protein	0.0016	0.0069	0.0175
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0018	0.0097	0.0114
Schistosoma mansoni	hypothetical protein	0.0017	0.0086	0.0099
Brugia malayi	hypothetical protein	0.0023	0.0158	0.046
Brugia malayi	RNA recognition motif domain containing protein	0.0064	0.0632	0.1996
Brugia malayi	GnHR receptor homolog	0.0023	0.0158	0.046
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Echinococcus granulosus	tm gpcr rhodopsin	0.0023	0.0158	0.0316
Brugia malayi	RNA binding protein	0.0064	0.0632	0.1996
Schistosoma mansoni	zinc finger protein	0.0016	0.0069	0.0075
Echinococcus granulosus	tumor protein p63	0.0343	0.3852	0.772
Echinococcus granulosus	neuropeptide Y receptor	0.0023	0.0158	0.0316
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0023	0.0158	0.0199
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0158	0.0158
Schistosoma mansoni	amine GPCR	0.0023	0.0158	0.0199
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0011	0.0015	0.0031
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0152	0.1645	0.3297
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Brugia malayi	follicle stimulating hormone receptor	0.0271	0.3026	0.974
Brugia malayi	putative neuropeptide receptor NPR1	0.0023	0.0158	0.046
Schistosoma mansoni	lamin	0.0029	0.0225	0.0294
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0632	0.0863
Onchocerca volvulus		0.005	0.0469	0.1469
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0219	0.0706
Echinococcus granulosus	neuropeptide receptor A26	0.0023	0.0158	0.0316
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.002	0.0116	0.0232
Echinococcus granulosus	allatostatin A receptor	0.0023	0.0158	0.0316
Trypanosoma cruzi	DNA polymerase kappa, putative	0.002	0.0116	1
Echinococcus granulosus	serotonin receptor	0.0023	0.0158	0.0316
Schistosoma mansoni	survival motor neuron protein	0.0052	0.0491	0.0665
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0015	0.0049
Echinococcus granulosus	hypothetical protein	0.0023	0.0158	0.0316
Brugia malayi	Bromodomain containing protein	0.0039	0.0338	0.1045
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0011	0.0015	0.0015
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0023	0.0158	0.0199
Entamoeba histolytica	hypothetical protein	0.0152	0.1645	1
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0028	0.0216	0.0658
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0158	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0023	0.0158	0.0158
Echinococcus multilocularis	lamin dm0	0.0029	0.0225	0.0225
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0023	0.0158	0.046
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0015	0.0049
Brugia malayi	hypothetical protein	0.0278	0.3106	1
Loa Loa (eye worm)	hypothetical protein	0.0072	0.0719	0.2313
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0017	0.0086	0.0277
Brugia malayi	G-protein coupled receptor	0.0023	0.0158	0.046
Echinococcus multilocularis	serotonin receptor	0.0023	0.0158	0.0158
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0023	0.0158	0.046
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0216	0.0696
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0017	0.0086	0.0172
Echinococcus multilocularis	allatostatin A receptor	0.0023	0.0158	0.0158
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0011	0.0015	0.0031
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0021	0.0133	0.1786
Schistosoma mansoni	hypothetical protein	0.0152	0.1645	0.2281
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0054	0.0511	0.1603
Onchocerca volvulus		0.0023	0.0158	0.046
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0023	0.0158	0.0158
Brugia malayi	G protein-coupled receptor	0.0023	0.0158	0.046
Loa Loa (eye worm)	hypothetical protein	0.0037	0.0314	0.1011
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0031	0.0247	0.0796
Echinococcus granulosus	tm gpcr rhodopsin	0.0023	0.0158	0.0316
Loa Loa (eye worm)	neuropeptide F receptor	0.0023	0.0158	0.0507
Schistosoma mansoni	hypothetical protein	0.0052	0.0491	0.0665
Brugia malayi	PHD-finger family protein	0.0027	0.0202	0.0603
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0023	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0023	0.0158	0.0158
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0011	0.0015	0.0049
Echinococcus multilocularis	g protein coupled receptor	0.0023	0.0158	0.0158
Schistosoma mansoni	neuropeptide receptor	0.0023	0.0158	0.0199
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0018	0.0097	0.0114
Onchocerca volvulus	Huntingtin homolog	0.0278	0.3106	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Onchocerca volvulus		0.0029	0.0225	0.068
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0021	0.0133	0.1786
Schistosoma mansoni	zinc finger protein	0.0022	0.0139	0.0173
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0011	0.0015	0.0031
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0011	0.0015	0.0049
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0158	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0066	0.0649	0.0887
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0061	0.0595	0.5
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0028	0.0216	1
Echinococcus granulosus	neuropeptides capa receptor	0.0023	0.0158	0.0316
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0045	0.0146
Trypanosoma cruzi	DNA polymerase eta, putative	0.002	0.0116	1
Brugia malayi	Bromodomain containing protein	0.0078	0.0789	0.2504
Echinococcus granulosus	histone lysine methyltransferase setb	0.0018	0.0097	0.0194
Echinococcus multilocularis	ecdysone induced protein 78C	0.0011	0.0015	0.0015
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0023	0.0158	0.0199
Schistosoma mansoni	hypothetical protein	0.0023	0.0158	0.0199
Schistosoma mansoni	growth hormone secretagogue receptor	0.0023	0.0158	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Onchocerca volvulus		0.0023	0.0158	0.046
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0011	0.0015	0.0015
Echinococcus granulosus	rhodopsin orphan GPCR	0.0023	0.0158	0.0316
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Brugia malayi	Serotonin receptor	0.0023	0.0158	0.046
Schistosoma mansoni	cpg binding protein	0.0035	0.029	0.0385
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0023	0.0158	0.0158
Echinococcus granulosus	tm gpcr rhodopsin	0.0023	0.0158	0.0316
Loa Loa (eye worm)	neuropeptide F receptor	0.0023	0.0158	0.0507
Trypanosoma brucei	ISWI complex protein	0.0016	0.0069	0.3322
Brugia malayi	Dopamine receptor protein 1	0.0023	0.0158	0.046
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0632	0.0863
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0367	0.1181
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Echinococcus granulosus	rhodopsin orphan GPCR	0.0023	0.0158	0.0316
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0021	0.0133	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0158	0.0158
Trypanosoma brucei	DNA polymerase IV, putative	0.002	0.0116	1
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0011	0.0015	0.0049
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0158	0.0199
Echinococcus multilocularis	neuropeptide Y receptor	0.0023	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Echinococcus granulosus	rhodopsin orphan GPCR	0.0023	0.0158	0.0316
Schistosoma mansoni	opsin-like receptor	0.0023	0.0158	0.0199
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0029	0.0225	0.0726
Entamoeba histolytica	hypothetical protein	0.0152	0.1645	1
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0023	0.0158	0.0316
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0023	0.0158	0.0158
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0011	0.0015	0.0031
Echinococcus granulosus	dna polymerase kappa	0.002	0.0116	0.0232
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0133	0.043
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.0036	0.0311	0.0622
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0632	0.0863
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0023	0.0158	0.0199
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0152	0.1645	0.1645
Onchocerca volvulus		0.0023	0.0158	0.046
Onchocerca volvulus		0.0023	0.0158	0.046
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0023	0.0158	0.0316
Echinococcus multilocularis	fetal alzheimer antigen, falz	0.0025	0.0174	0.0174
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0011	0.0015	0.0015
Echinococcus granulosus	ecdysone induced protein 78C	0.0011	0.0015	0.0031
Loa Loa (eye worm)	hypothetical protein	0.005	0.0469	0.1511
Echinococcus granulosus	survival motor neuron protein 1	0.0255	0.2838	0.5688
Schistosoma mansoni	amine GPCR	0.0023	0.0158	0.0199
Echinococcus granulosus	orexin receptor type 2	0.0023	0.0158	0.0316
Echinococcus multilocularis	tumor protein p63	0.0343	0.3852	0.3852
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Echinococcus multilocularis	musashi	0.0029	0.0225	0.0225
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0023	0.0158	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Brugia malayi	CXXC zinc finger family protein	0.0031	0.0247	0.0751
Loa Loa (eye worm)	hypothetical protein	0.0278	0.3106	1
Echinococcus multilocularis	neuropeptides capa receptor	0.0023	0.0158	0.0158
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0023	0.0158	0.0316
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Plasmodium falciparum	acyl-CoA synthetase	0.0021	0.0133	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0158	0.0158
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0116	1
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0271	0.3026	0.9741
Leishmania major	4-coumarate:coa ligase-like protein	0.0028	0.0216	1
Echinococcus multilocularis	serotonin receptor	0.0023	0.0158	0.0158
Schistosoma mansoni	acetyl-CoA C-acetyltransferase	0.0025	0.0174	0.0222
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0028	0.0216	1
Schistosoma mansoni	methyl-cpg binding protein mbd	0.0017	0.0089	0.0104
Leishmania major	4-coumarate:coa ligase-like protein	0.0028	0.0216	1
Schistosoma mansoni	hypothetical protein	0.0023	0.0158	0.0199
Schistosoma mansoni	hypothetical protein	0.0017	0.0086	0.0099
Brugia malayi	ImpB/MucB/SamB family protein	0.002	0.0116	0.0324
Onchocerca volvulus		0.0023	0.0158	0.046
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0028	0.0216	0.5
Onchocerca volvulus		0.0028	0.0216	0.065
Echinococcus granulosus	cytoplasmic intermediate filament protein	0.0014	0.0051	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Mycobacterium ulcerans	acyl-CoA synthetase	0.0028	0.0216	1
Echinococcus multilocularis	FTZ F1 alpha	0.0011	0.0015	0.0015
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0023	0.0158	0.046
Schistosoma mansoni	hypothetical protein	0.0023	0.0158	0.0199
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0158	0.0158
Echinococcus multilocularis	dro:myosuppressin receptor	0.0023	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0133	0.043
Brugia malayi	AKH receptor	0.0023	0.0158	0.046
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.002	0.012	0.046
Echinococcus granulosus	neuropeptide FF receptor 2	0.0023	0.0158	0.0316
Echinococcus multilocularis	neuropeptide receptor A26	0.0023	0.0158	0.0158
Schistosoma mansoni	neuropeptide receptor	0.0023	0.0158	0.0199
Brugia malayi	hypothetical protein	0.0152	0.1645	0.5272
Brugia malayi	neuropeptide F receptor	0.0023	0.0158	0.046
Echinococcus multilocularis	neuropeptide receptor	0.0023	0.0158	0.0158
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0023	0.0158	0.046
Onchocerca volvulus		0.0023	0.0158	0.046
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Echinococcus multilocularis	dna polymerase eta	0.002	0.0116	0.0116
Schistosoma mansoni	hypothetical protein	0.0037	0.0314	0.0418
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.002	0.012	0.046
Echinococcus granulosus	7tm_1 domain containing protein	0.0023	0.0158	0.0316
Echinococcus granulosus	fmrfamide receptor	0.0023	0.0158	0.0316
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0015	0.0049
Echinococcus multilocularis	neuropeptide Y receptor	0.0023	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0133	0.043
Echinococcus multilocularis	fmrfamide receptor	0.0023	0.0158	0.0158
Brugia malayi	hypothetical protein	0.0255	0.2838	0.9132
Brugia malayi	hypothetical protein	0.0023	0.0158	0.046
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.002	0.0116	0.0116
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0023	0.0158	0.0158
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0011	0.0015	0.0049
Echinococcus granulosus	methyl CpG binding domain protein 2	0.0017	0.0089	0.0179
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0011	0.0015	0.0015
Leishmania major	4-coumarate:coa ligase-like protein	0.0028	0.0216	1
Schistosoma mansoni	cpg binding protein	0.0031	0.0247	0.0325
Trypanosoma brucei	unspecified product	0.002	0.0116	1
Mycobacterium ulcerans	hypothetical protein	0.0028	0.0216	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0116	1
Entamoeba histolytica	hypothetical protein	0.0152	0.1645	1
Schistosoma mansoni	neuropeptide receptor	0.0023	0.0158	0.0199
Schistosoma mansoni	bromodomain containing protein	0.0066	0.0652	0.0891
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0023	0.0158	0.046
Schistosoma mansoni	myosin xvIII	0.0023	0.0158	0.0199
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0116	1
Echinococcus multilocularis	tar DNA binding protein	0.0064	0.0632	0.0632
Loa Loa (eye worm)	TAR-binding protein	0.0064	0.0632	0.2035
Brugia malayi	F/Y-rich N-terminus family protein	0.0011	0.0021	0.0019
Loa Loa (eye worm)	G-protein coupled receptor	0.0023	0.0158	0.0507
Echinococcus multilocularis	neuropeptide receptor	0.0023	0.0158	0.0158
Echinococcus multilocularis	cpg binding protein	0.0035	0.029	0.029
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0023	0.0158	0.0158
Loa Loa (eye worm)	PHD-finger family protein	0.0021	0.0131	0.0422
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0028	0.0216	1
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0023	0.0158	0.0199
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0023	0.0158	0.0507
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0023	0.0158	0.0316
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0011	0.0015	0.0031
Echinococcus multilocularis	neuropeptide s receptor	0.0023	0.0158	0.0158
Trypanosoma brucei	DNA polymerase IV, putative	0.002	0.0116	1
Brugia malayi	neuropeptide F receptor	0.0023	0.0158	0.046
Loa Loa (eye worm)	melatonin receptor type 1A	0.0023	0.0158	0.0507
Onchocerca volvulus		0.0023	0.0158	0.046
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0017	0.0086	0.0172
Echinococcus multilocularis	orexin receptor type 2	0.0023	0.0158	0.0158
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.002	0.0116	0.0372
Echinococcus multilocularis	methyl CpG binding domain protein 2	0.0017	0.0089	0.0089
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Schistosoma mansoni	cpg binding protein	0.0035	0.029	0.0385
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0028	0.0216	0.5
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0052	0.0491	0.1538
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0158	0.0158
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0023	0.0158	0.0316
Echinococcus granulosus	rhodopsin orphan GPCR	0.0023	0.0158	0.0316
Echinococcus granulosus	dnaJ subfamily B	0.0441	0.4989	1
Echinococcus multilocularis	dnaJ subfamily B	0.0441	0.4989	0.4989
Echinococcus granulosus	g-protein coupled receptor	0.0023	0.0158	0.0316
Echinococcus multilocularis	GPCR, family 2	0.0017	0.0086	0.0086
Echinococcus granulosus	somatostatin receptor	0.0023	0.0158	0.0316
Schistosoma mansoni	neuropeptide f receptor 76f	0.0023	0.0158	0.0199
Echinococcus granulosus	neuropeptide s receptor	0.0023	0.0158	0.0316
Echinococcus granulosus	neuropeptide receptor	0.0023	0.0158	0.0316
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0018	0.0097	0.0097
Onchocerca volvulus		0.0023	0.0158	0.046
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0015	0.0049
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0023	0.0158	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0051	0.0166
Loa Loa (eye worm)	RNA binding protein	0.0064	0.0632	0.2035
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0011	0.0015	0.0015
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0023	0.0158	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0216	0.0696
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0158	0.0199
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.0062	0.061	0.1222
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0015	0.0049
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Onchocerca volvulus		0.0023	0.0158	0.046
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0017	0.0086	0.0086
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0023	0.0158	0.046
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0158	0.0199
Echinococcus granulosus	sex peptide receptor	0.0023	0.0158	0.0316
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0023	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0011	0.0015	0.0049
Brugia malayi	Latrophilin receptor protein 2	0.0017	0.0086	0.0229
Brugia malayi	AMP-binding enzyme family protein	0.0028	0.0216	0.065
Schistosoma mansoni	opsin-like receptor	0.0023	0.0158	0.0199
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0158	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0278	0.3106	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Echinococcus granulosus	G protein coupled receptor 139	0.0023	0.0158	0.0316
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Onchocerca volvulus		0.0023	0.0158	0.046
Echinococcus granulosus	fetal alzheimer antigen falz	0.0025	0.0174	0.0349
Echinococcus granulosus	g protein coupled receptor	0.0023	0.0158	0.0316
Echinococcus granulosus	rhodopsin orphan GPCR	0.0023	0.0158	0.0316
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0023	0.0158	0.046
Echinococcus granulosus	FTZ F1 alpha	0.0011	0.0015	0.0031
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0015	0.0049
Loa Loa (eye worm)	TYRA-2 protein	0.0023	0.0158	0.0507
Brugia malayi	RE15519p	0.0023	0.0158	0.046
Echinococcus granulosus	neuropeptide Y receptor	0.0023	0.0158	0.0316
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0023	0.0158	0.0158
Trypanosoma brucei	DNA polymerase eta, putative	0.002	0.0116	1
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.002	0.012	0.046
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Brugia malayi	ORL1-like opioid receptor	0.0023	0.0158	0.046
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0017	0.0086	0.0086
Echinococcus multilocularis	fmrfamide receptor	0.0023	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0086	0.0277
Trypanosoma cruzi	DNA polymerase kappa, putative	0.002	0.0116	1
Brugia malayi	hypothetical protein	0.0023	0.0158	0.046
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0632	0.0863
Schistosoma mansoni	neuropeptide F-like receptor	0.0023	0.0158	0.0199
Echinococcus granulosus	cpg binding protein	0.0035	0.029	0.0581
Schistosoma mansoni	hypothetical protein	0.0629	0.716	1
Brugia malayi	hypothetical protein	0.0023	0.0158	0.046
Schistosoma mansoni	intermediate filament proteins	0.0029	0.0225	0.0294
Loa Loa (eye worm)	cytoplasmic intermediate filament protein	0.0016	0.0069	0.0223
Schistosoma mansoni	biogenic amine receptor	0.0023	0.0158	0.0199
Echinococcus multilocularis	dna polymerase kappa	0.002	0.0116	0.0116
Brugia malayi	Dopamine receptor	0.0023	0.0158	0.046
Mycobacterium ulcerans	acyl-CoA synthetase	0.0028	0.0216	1
Onchocerca volvulus		0.0023	0.0158	0.046
Echinococcus multilocularis	g-protein coupled receptor	0.0023	0.0158	0.0158
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0023	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0054	0.0511	0.1644
Trichomonas vaginalis	DNA polymerase eta, putative	0.002	0.0116	0.5
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0023	0.0158	0.0199
Schistosoma mansoni	hypothetical protein	0.0017	0.0086	0.0099
Schistosoma mansoni	hypothetical protein	0.0021	0.0131	0.0162
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.002	0.0116	0.5
Brugia malayi	intermediate filament protein	0.0029	0.0225	0.068
Loa Loa (eye worm)	bromodomain containing protein	0.0018	0.0096	0.031
Plasmodium vivax	acyl-CoA synthetase, putative	0.0021	0.0133	0.5
Brugia malayi	hypothetical protein	0.0023	0.0158	0.046
Schistosoma mansoni	methyl-cpg binding protein mbd	0.0017	0.0089	0.0104
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0023	0.0158	0.0199
Echinococcus multilocularis	sex peptide receptor	0.0023	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0339	0.1092
Onchocerca volvulus		0.0023	0.0158	0.046
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0116	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Schistosoma mansoni	DNA polymerase eta	0.002	0.0116	0.014
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0023	0.0158	0.0316
Schistosoma mansoni	cellular tumor antigen P53	0.005	0.0469	0.0635
Echinococcus multilocularis	zinc finger protein	0.0022	0.0139	0.0139
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0028	0.0216	1
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0011	0.0015	0.0015
Brugia malayi	latrophilin 2 splice variant baaae	0.0037	0.0314	0.0967
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Entamoeba histolytica	hypothetical protein	0.0152	0.1645	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Echinococcus granulosus	biogenic amine 5HT receptor	0.0023	0.0158	0.0316
Trypanosoma cruzi	DNA polymerase kappa, putative	0.002	0.0116	1
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0023	0.0158	0.0158
Echinococcus granulosus	neuropeptide receptor	0.0023	0.0158	0.0316
Schistosoma mansoni	transcription factor LCR-F1	0.0152	0.1645	0.2281
Schistosoma mansoni	amine GPCR	0.0023	0.0158	0.0199
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0011	0.0015	0.0031
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0133	0.043
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0023	0.0158	0.0316
Schistosoma mansoni	neuropeptide receptor	0.0023	0.0158	0.0199
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0023	0.0158	0.0507
Trypanosoma brucei	DNA polymerase IV, putative	0.002	0.0116	1
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0023	0.0158	0.0316
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.0062	0.061	0.061
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Brugia malayi	hypothetical protein	0.0023	0.0158	0.046
Echinococcus granulosus	dro:myosuppressin receptor	0.0023	0.0158	0.0316
Echinococcus multilocularis	somatostatin receptor	0.0023	0.0158	0.0158
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.002	0.012	0.046
Echinococcus granulosus	biogenic amine 5HT receptor	0.0023	0.0158	0.0316
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0225	0.0726
Echinococcus granulosus	GPCR family 2	0.0017	0.0086	0.0172
Echinococcus multilocularis	G protein coupled receptor 139	0.0023	0.0158	0.0158
Echinococcus multilocularis	neuropeptides capa receptor	0.0023	0.0158	0.0158
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0023	0.0158	0.0199
Echinococcus granulosus	tar DNA binding protein	0.0064	0.0632	0.1267
Schistosoma mansoni	adenoreceptor	0.0023	0.0158	0.0199
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0011	0.0015	0.0049
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0116	1
Onchocerca volvulus		0.0023	0.0158	0.046
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0133	0.043
Schistosoma mansoni	amine GPCR	0.0023	0.0158	0.0199
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0023	0.0158	0.0199
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0023	0.0158	0.0199
Echinococcus multilocularis	g protein coupled receptor	0.0023	0.0158	0.0158
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0028	0.0216	0.0658
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0023	0.0158	0.0158
Schistosoma mansoni	hypothetical protein	0.0017	0.0086	0.0099
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0023	0.0158	0.0158
Echinococcus granulosus	zinc finger protein	0.0022	0.0139	0.0279
Leishmania major	DNA polymerase kappa, putative,DNA polymerase IV, putative	0.002	0.0116	0.318
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Echinococcus multilocularis	cytoplasmic intermediate filament protein	0.0014	0.0051	0.0051
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.002	0.0116	0.014
Mycobacterium ulcerans	acyl-CoA synthetase	0.0028	0.0216	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Brugia malayi	putative neuropeptide receptor	0.0023	0.0158	0.046
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0023	0.0158	0.0199
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0023	0.0158	0.046
Echinococcus granulosus	dna polymerase eta	0.002	0.0116	0.0232
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0158	0.0199
Leishmania major	DNA polymerase eta, putative	0.002	0.0116	0.318
Brugia malayi	ImpB/MucB/SamB family protein	0.002	0.0116	0.0324
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0054	0.0511	0.1644
Entamoeba histolytica	acyl-coA synthetase, putative	0.0028	0.0216	0.0658
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0158	0.0158
Onchocerca volvulus		0.0023	0.0158	0.046
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0017	0.0086	0.0229
Echinococcus multilocularis	g protein coupled receptor	0.0023	0.0158	0.0158
Brugia malayi	hypothetical protein	0.0023	0.0158	0.046
Loa Loa (eye worm)	hypothetical protein	0.0045	0.041	0.1319
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Echinococcus granulosus	lamin dm0	0.0029	0.0225	0.0452
Onchocerca volvulus		0.0023	0.0158	0.046
Brugia malayi	hypothetical protein	0.0023	0.0158	0.046
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0632	0.0863
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0054	0.0511	0.1603
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0116	1
Brugia malayi	hypothetical protein	0.0023	0.0158	0.046
Onchocerca volvulus		0.0052	0.0491	0.1538
Echinococcus granulosus	rhodopsin orphan GPCR	0.0023	0.0158	0.0316
Schistosoma mansoni	opsin-like receptor	0.0023	0.0158	0.0199
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0023	0.0158	0.0199
Loa Loa (eye worm)	steroid hormone receptor	0.0011	0.0015	0.0049
Loa Loa (eye worm)	hypothetical protein	0.0011	0.0015	0.0049
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0011	0.0015	0.0015
Schistosoma mansoni	histamine h1 receptor	0.0023	0.0158	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Brugia malayi	Melatonin receptor type 1A	0.0023	0.0158	0.046
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0158	0.0199
Brugia malayi	TAR-binding protein	0.0064	0.0632	0.1996
Schistosoma mansoni	biogenic amine receptor	0.0023	0.0158	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0255	0.2838	0.9136
Brugia malayi	Dopamine receptor protein 2	0.0023	0.0158	0.046
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0064	0.0632	0.2035
Brugia malayi	Intermediate filament tail domain containing protein	0.0029	0.0225	0.068
Leishmania major	DNA polymerase kappa, putative	0.002	0.0116	0.318
Loa Loa (eye worm)	G-protein coupled receptor	0.0023	0.0158	0.0507
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0023	0.0158	0.0158
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Schistosoma mansoni	lamin	0.0029	0.0225	0.0294
Brugia malayi	sulfakinin receptor protein	0.0023	0.0158	0.046
Schistosoma mansoni	terminal deoxycytidyl transferase	0.002	0.0116	0.014
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0216	0.0696
Schistosoma mansoni	neuropeptide F-like receptor	0.0023	0.0158	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0158	0.0507
Loa Loa (eye worm)	intermediate filament protein	0.0029	0.0225	0.0726
Trypanosoma brucei	DNA polymerase kappa, putative	0.002	0.0116	1
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0028	0.0216	1
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0023	0.0158	0.0507

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1183426

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1170387