Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0047 | 0.0033 | 0.0107 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0047 | 0.0033 | 0.0107 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0253 | 0.273 | 0.8711 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0033 | 0.0107 |
Schistosoma mansoni | hypothetical protein | 0.0102 | 0.0747 | 0.2383 |
Echinococcus granulosus | tar DNA binding protein | 0.0253 | 0.273 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0147 | 0.1334 | 0.4258 |
Schistosoma mansoni | glutaminase | 0.0284 | 0.3134 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0253 | 0.273 | 0.273 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.1334 | 0.4258 |
Loa Loa (eye worm) | TAR-binding protein | 0.0253 | 0.273 | 0.8711 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0102 | 0.0747 | 0.2383 |
Schistosoma mansoni | tar DNA-binding protein | 0.0253 | 0.273 | 0.8711 |
Loa Loa (eye worm) | glutaminase 2 | 0.0284 | 0.3134 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0033 | 0.0107 |
Brugia malayi | glutaminase DH11.1 | 0.0284 | 0.3134 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0253 | 0.273 | 0.8711 |
Schistosoma mansoni | tar DNA-binding protein | 0.0253 | 0.273 | 0.8711 |
Loa Loa (eye worm) | glutaminase | 0.0284 | 0.3134 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0047 | 0.0033 | 0.0033 |
Schistosoma mansoni | tar DNA-binding protein | 0.0253 | 0.273 | 0.8711 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0224 | 0.2342 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0551 | 0.1757 |
Echinococcus multilocularis | GPCR, family 2 | 0.0047 | 0.0033 | 0.0033 |
Mycobacterium ulcerans | glutaminase | 0.0284 | 0.3134 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0047 | 0.0033 | 0.0122 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0149 | 0.1362 | 0.4344 |
Echinococcus granulosus | muscleblind protein | 0.0147 | 0.1334 | 0.4887 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0747 | 0.2383 |
Schistosoma mansoni | tar DNA-binding protein | 0.0253 | 0.273 | 0.8711 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0149 | 0.1362 | 0.4344 |
Brugia malayi | hypothetical protein | 0.0087 | 0.0551 | 0.1757 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0047 | 0.0033 | 0.0122 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0033 | 0.0107 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0149 | 0.1362 | 0.4344 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0033 | 0.0107 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0047 | 0.0033 | 0.0033 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0147 | 0.1334 | 0.1334 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0047 | 0.0033 | 0.0107 |
Schistosoma mansoni | eyes absent homolog | 0.0087 | 0.0551 | 0.1757 |
Loa Loa (eye worm) | RNA binding protein | 0.0253 | 0.273 | 0.8711 |
Trichomonas vaginalis | glutaminase, putative | 0.0284 | 0.3134 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0033 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.1334 | 0.4258 |
Schistosoma mansoni | tar DNA-binding protein | 0.0253 | 0.273 | 0.8711 |
Echinococcus multilocularis | muscleblind protein | 0.0147 | 0.1334 | 0.1334 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0551 | 0.1757 |
Brugia malayi | RNA binding protein | 0.0253 | 0.273 | 0.8711 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1362 | 0.4344 |
Brugia malayi | TAR-binding protein | 0.0253 | 0.273 | 0.8711 |
Echinococcus granulosus | GPCR family 2 | 0.0047 | 0.0033 | 0.0122 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.