Detailed information for compound 1172309

Basic information

Technical information
  • TDR Targets ID: 1172309
  • Name: 2-(3,4-dimethoxyphenyl)-5-[2-(4-hydroxy-3,5-d iiodophenyl)ethyl-methylamino]-2-propan-2-ylp entanenitrile
  • MW: 662.342 | Formula: C25H32I2N2O3
  • H donors: 1 H acceptors: 2 LogP: 6.36 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: N#CC(c1ccc(c(c1)OC)OC)(C(C)C)CCCN(CCc1cc(I)c(c(c1)I)O)C
  • InChi: 1S/C25H32I2N2O3/c1-17(2)25(16-28,19-7-8-22(31-4)23(15-19)32-5)10-6-11-29(3)12-9-18-13-20(26)24(30)21(27)14-18/h7-8,13-15,17,30H,6,9-12H2,1-5H3
  • InChiKey: XCZSSXHURZNHDW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(3,4-dimethoxyphenyl)-5-[2-(4-hydroxy-3,5-diiodo-phenyl)ethyl-methyl-amino]-2-isopropyl-pentanenitrile
  • 2-(3,4-dimethoxyphenyl)-5-[2-(4-hydroxy-3,5-diiodophenyl)ethyl-methylamino]-2-isopropylpentanenitrile
  • 2-(3,4-dimethoxyphenyl)-5-[2-(4-hydroxy-3,5-diiodo-phenyl)ethyl-methyl-amino]-2-isopropyl-valeronitrile
  • 2-(3,4-dimethoxyphenyl)-5-[2-(4-hydroxy-3,5-diiodo-phenyl)ethyl-methyl-amino]-2-propan-2-yl-pentanenitrile

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica proteasome regulatory subunit, putative 0.0038 0.0128 0.0128
Leishmania major proteasome beta 2 subunit, putative 0.031 0.2217 0.2217
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.0396 0.0396
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0033 0.009 0.009
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0033 0.009 0.009
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0064 0.0331 0.033
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.006 0.0296 0.0296
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0322 0.0322
Leishmania major proteasome regulatory ATPase subunit 2, putative 0.0023 0.0014 0.0014
Giardia lamblia 26S protease regulatory subunit 8 0.0022 0.0009 0.0009
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0286 0.2035 0.2028
Toxoplasma gondii PCI domain-containing protein 0.0042 0.0157 0.0148
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0035 0.0104 0.0104
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0033 0.009 0.009
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0009 0.0009
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.031 0.2217 0.2217
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0571 0.0571
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 3, putative 0.0045 0.0181 0.0181
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0009 0.0009
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0265 0.1875 0.1875
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0009 0.0009
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0059 0.0059
Brugia malayi hypothetical protein 0.0063 0.0322 0.0322
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0063 0.0322 0.0322
Giardia lamblia Proteasome subunit beta type 5 precursor 0.1322 1 1
Echinococcus granulosus 26S proteasome regulatory subunit N1 0.0035 0.0102 0.0102
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0271 0.1922 0.1922
Entamoeba histolytica proteasome regulatory subunit, putative 0.0024 0.0024 0.0024
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0314 0.2251 0.2244
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0009 0.0008
Echinococcus multilocularis microtubule associated protein 2 0.0761 0.569 0.569
Echinococcus multilocularis geminin 0.02 0.1376 0.1376
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0517 0.3815 0.3809
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0064 0.0331 0.033
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0014
Giardia lamblia Proteasome subunit beta type 3 0.0265 0.1875 0.1875
Mycobacterium leprae proteasome (beta subunit) PrcB 0.1322 1 1
Echinococcus multilocularis 26S protease regulatory subunit 8 0.0022 0.0009 0.0009
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.006 0.0296 0.0296
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0265 0.1875 0.1875
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0039 0.0133 0.0133
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0042 0.0157 0.0157
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0009 0.0009
Echinococcus granulosus netrin receptor unc 5 0.0039 0.0133 0.0133
Leishmania major proteasome alpha 7 subunit, putative 0.0328 0.2361 0.2361
Schistosoma mansoni multiubiquitin binding protein S5a 0.0024 0.0024 0.0024
Trypanosoma brucei proteasome regulatory non-ATPase subunit 6 0.0042 0.0157 0.0157
Echinococcus granulosus proteasome subunit beta t family 0.0265 0.1875 0.1875
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0235 0.1641 0.1641
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0024 0.0025 0.0025
Plasmodium vivax 26S proteasome regulatory subunit RPN13, putative 0.0064 0.0331 0.0322
Plasmodium vivax proteasome subunit beta type-4, putative 0.0263 0.1861 0.1853
Loa Loa (eye worm) proteasome 26S subunit 0.0022 0.0009 0.0009
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0278 0.197 0.197
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0571 0.0571
Giardia lamblia Proteasome subunit beta type 2 0.031 0.2217 0.2217
Schistosoma mansoni 26s proteasome non-ATPase regulatory subunit 4 0.0024 0.0024 0.0024
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0009 0.0009
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0024 0.0025 0.0025
Leishmania major proteasome alpha 1 subunit, putative 0.0271 0.1922 0.1922
Brugia malayi Protein kinase domain containing protein 0.0039 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0263 0.1861 0.1861
Brugia malayi Trypsin family protein 0.0063 0.0322 0.0322
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0352 0.0352
Brugia malayi Death domain containing protein 0.0039 0.0133 0.0133
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0263 0.1861 0.1861
Plasmodium vivax 26S protease regulatory subunit 6a, putative 0.0024 0.0025 0.0016
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0263 0.1861 0.1861
Loa Loa (eye worm) proteasome regulatory particle 0.0042 0.0157 0.0157
Onchocerca volvulus 0.0063 0.0322 0.0874
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0328 0.2361 0.2354
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0272 0.193 0.193
Loa Loa (eye worm) hypothetical protein 0.0033 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0039 0.0133 0.0133
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0352 0.0352
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0009 0.0009
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0314 0.2251 0.225
Trypanosoma brucei proteasome regulatory ATPase subunit 2 0.0023 0.0014 0.0014
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.1322 1 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0009 0.0009
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0328 0.2361 0.2361
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0023 0.0014 0.0014
Toxoplasma gondii hypothetical protein 0.0033 0.0089 0.008
Plasmodium vivax 26S proteasome regulatory subunit RPN9, putative 0.0035 0.0102 0.0093
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0059 0.0059
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0009 0.0009
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0285 0.2027 0.2027
Plasmodium vivax 26S proteasome regulatory subunit RPN8, putative 0.0035 0.0104 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0009 0.0008
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0033 0.009 0.009
Brugia malayi Proteasome/cyclosome repeat family protein 0.003 0.007 0.007
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0322 0.0322
Brugia malayi hypothetical protein 0.0489 0.3594 0.3594
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0328 0.2361 0.2361
Schistosoma mansoni carbonic anhydrase-related 0.0033 0.0089 0.0089
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0893 0.6706 0.6706
Schistosoma mansoni gamma-secretase subunit aph-1 0.0108 0.0664 0.0664
Trypanosoma brucei proteasome regulatory ATPase subunit 5 0.0024 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0029 0.0059 0.0058
Toxoplasma gondii proteasome subunit 0.0272 0.193 0.1923
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0272 0.193 0.1923
Echinococcus granulosus proteasome 26s subunit subunit 4 atpase 0.0023 0.0014 0.0014
Leishmania major proteasome regulatory non-ATP-ase subunit 11, putative,19S proteasome regulatory subunit, Metallo- peptidase, Clan MP, Family M6 0.0022 0.0003 0.0002
Brugia malayi proteasome subunit alpha type 6 0.0286 0.2035 0.2035
Echinococcus granulosus Ankyrin 0.0039 0.0134 0.0134
Schistosoma mansoni 26S protease regulatory subunit 6b 0.0023 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0089
Echinococcus granulosus proteasome subunit beta type 7 0.0893 0.6706 0.6706
Echinococcus multilocularis enteropeptidase 0.0063 0.0322 0.0322
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0033 0.0089 0.0089
Plasmodium vivax 26S proteasome regulatory subunit RPN7, putative 0.0038 0.0127 0.0118
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0033 0.009 0.009
Echinococcus granulosus 26S protease regulatory subunit 8 0.0022 0.0009 0.0009
Giardia lamblia Non ATPase subunit MPR1 of 26S proteasome 0.0022 0.0003 0.0002
Echinococcus multilocularis netrin receptor unc 5 0.0039 0.0133 0.0133
Brugia malayi Probable 26S protease regulatory subunit S10B 0.0022 0.0009 0.0009
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0009 0.0009
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.1322 1 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.005 0.005
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0009 0.0009
Echinococcus granulosus geminin 0.02 0.1376 0.1376
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 12 0.0038 0.0128 0.0128
Schistosoma mansoni 26S protease regulatory subunit 0.0022 0.0009 0.0009
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0517 0.3815 0.3815
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0314 0.2251 0.225
Onchocerca volvulus Notchless protein homolog 0.0274 0.1941 0.5389
Brugia malayi cathepsin B-like cysteine proteinase 0.0063 0.0324 0.0324
Brugia malayi 26S proteasome subunit P45 family protein 0.0023 0.0014 0.0014
Echinococcus granulosus cathepsin b 0.0063 0.0324 0.0324
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0022 0.0003 0.0002
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0024 0.0024 0.0024
Brugia malayi small heat shock protein 0.0341 0.2461 0.2461
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0039 0.0133 0.0133
Onchocerca volvulus 0.0063 0.0322 0.0874
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0328 0.2361 0.2361
Echinococcus granulosus transmembrane protease serine 3 0.0063 0.0322 0.0322
Giardia lamblia 26S protease regulatory subunit 7 0.0022 0.0009 0.0009
Leishmania major proteasome regulatory ATPase subunit 0.0022 0.0009 0.0009
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 12 0.0038 0.0128 0.0128
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0161 0.0161
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0009 0.0009
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0024 0.0025 0.0024
Brugia malayi proteasome subunit alpha type 4 0.0253 0.1783 0.1783
Onchocerca volvulus Netrin receptor homolog 0.0039 0.0133 0.0347
Loa Loa (eye worm) hypothetical protein 0.0063 0.0324 0.0324
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.031 0.2217 0.2217
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0063 0.0324 0.0324
Plasmodium vivax proteasome subunit beta type-1, putative 0.0517 0.3815 0.3809
Loa Loa (eye worm) hypothetical protein 0.0413 0.3008 0.3008
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 0.0033 0.009 0.009
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0271 0.1922 0.1922
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0271 0.1922 0.1922
Mycobacterium ulcerans proteasome PrcA 0.0235 0.1641 0.1641
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0009 0.0009
Plasmodium falciparum 26S proteasome regulatory subunit RPN1, putative 0.0047 0.0194 0.0185
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0024 0.0019 0.0019
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0033 0.0089 0.0089
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.1322 1 1
Echinococcus granulosus carbonic anhydrase 0.0033 0.0089 0.0089
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0274 0.1941 0.1941
Leishmania major proteasome beta 3 subunit, putative 0.0265 0.1875 0.1875
Brugia malayi proteasome subunit alpha type 1 0.0271 0.1922 0.1922
Echinococcus granulosus 26s protease regulatory subunit s10b 0.0022 0.0009 0.0009
Giardia lamblia 20S proteasome alpha subunit 5 0.0285 0.2027 0.2027
Brugia malayi PCI domain containing protein 0.0035 0.0102 0.0102
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0352 0.0351
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0047 0.0194 0.0194
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0278 0.197 0.197
Mycobacterium ulcerans hypothetical protein 0.0063 0.0322 0.0322
Trichomonas vaginalis 26S proteasome subunit, putative 0.0035 0.0102 0.0102
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0009 0.0009
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0036 0.011 0.011
Toxoplasma gondii 26S proteasome regulatory subunit 6b, putative 0.0023 0.0014 0.0005
Mycobacterium ulcerans proteasome PrcB 0.1322 1 1
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0047 0.0194 0.0194
Trichomonas vaginalis 26S proteasome subunit S9, putative 0.0042 0.0157 0.0157
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0059 0.0059
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0235 0.1641 0.1641
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0272 0.1926 0.1919
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0286 0.2035 0.2035
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0296 0.0296
Giardia lamblia 20S proteasome alpha subunit 6 0.0271 0.1922 0.1922
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0285 0.2027 0.2027
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0089
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.1322 1 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Trypanosoma cruzi Aph-1 protein, putative 0.0042 0.0159 0.0159
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0033 0.009 0.009
Brugia malayi Proteasome A-type and B-type family protein 0.0272 0.193 0.193
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0571 0.0571
Plasmodium falciparum 26S proteasome regulatory subunit RPN8, putative 0.0035 0.0104 0.0095
Schistosoma mansoni hypothetical protein 0.0033 0.009 0.009
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.0396 0.0396
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 6 0.0038 0.0127 0.0127
Toxoplasma gondii 26S protease regulatory subunit 4, putative 0.0023 0.0014 0.0005
Loa Loa (eye worm) PCI domain-containing protein 0.0038 0.0128 0.0127
Toxoplasma gondii proteasome regulatory subunit 0.0035 0.0104 0.0095
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0314 0.2251 0.225
Loa Loa (eye worm) hypothetical protein 0.0033 0.009 0.009
Onchocerca volvulus 0.0063 0.0322 0.0874
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0322 0.0322
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0063 0.0322 0.0322
Schistosoma mansoni 26S protease regulatory subunit 0.0023 0.0014 0.0014
Schistosoma mansoni microtubule-associated protein tau 0.0761 0.569 0.569
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0035 0.0102 0.0102
Leishmania major proteasome beta 5 subunit, putative 0.1322 1 1
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.031 0.2217 0.2217
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0274 0.1941 0.1941
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0322 0.0322
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0517 0.3815 0.3815
Entamoeba histolytica proteasome regulatory subunit, putative 0.0042 0.0157 0.0157
Toxoplasma gondii proteasome subunit beta type, putative 0.1322 1 1
Onchocerca volvulus 0.0023 0.0014 0.0015
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.003 0.007 0.007
Schistosoma mansoni hypothetical protein 0.01 0.0608 0.0608
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0035 0.0104 0.0104
Trypanosoma cruzi Aph-1 protein, putative 0.0042 0.0159 0.0159
Trypanosoma cruzi serine peptidase, Clan SJ, family S16, putative 0.0022 0.0009 0.0009
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0042 0.0157 0.0157
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0517 0.3815 0.3815
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0322 0.0322
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 5, putative 0.0038 0.0128 0.0127
Toxoplasma gondii Proteasome/cyclosome repeat-containing protein 0.0036 0.011 0.0101
Schistosoma mansoni coup transcription factor 0.0022 0.0009 0.0009
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0064 0.0331 0.033
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0039 0.0134 0.0134
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0063 0.0324 0.0324
Echinococcus multilocularis 26S proteasome regulatory subunit T3 0.0023 0.0014 0.0014
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 6, putative 0.0042 0.0157 0.0157
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0328 0.2361 0.2361
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0263 0.1861 0.1861
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.031 0.2217 0.2217
Trypanosoma brucei proteasome alpha 7 subunit 0.0274 0.1941 0.1941
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0038 0.0127 0.0127
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0517 0.3815 0.3815
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0022 0.0009 0.0009
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0377 0.2737 0.2737
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0022 0.0003 0.0003
Trichomonas vaginalis regulatory particle non-ATPase, putative 0.0035 0.0102 0.0102
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0271 0.1922 0.1922
Toxoplasma gondii proteasome subunit alpha1, putative 0.0286 0.2035 0.2028
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0047 0.0194 0.0194
Trypanosoma brucei protease regulatory ATPase subunit 4 0.0022 0.0009 0.0009
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0271 0.1922 0.1922
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.006 0.0296 0.0296
Brugia malayi Chain A, Structure Of A Brca2-Dss1 Complex. 0.0246 0.173 0.173
Loa Loa (eye worm) 26S proteasome regulatory complex subunit p97 0.0047 0.0194 0.0194
Trypanosoma brucei 19S proteasome non-atpase subunit 8 0.0035 0.0104 0.0104
Loa Loa (eye worm) proteasome/cyclosome repeat family protein 0.003 0.007 0.007
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0207 0.0207
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0352 0.0351
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0009 0.0009
Leishmania major proteasome regulatory ATPase subunit 5, putative 0.0024 0.0025 0.0024
Brugia malayi proteasome subunit alpha type 3 0.0274 0.1941 0.1941
Schistosoma mansoni 26S protease regulatory subunit S10b 0.0022 0.0009 0.0009
Onchocerca volvulus 0.0029 0.0059 0.0139
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0088 0.0517 0.0517
Toxoplasma gondii hypothetical protein 0.003 0.0071 0.0062
Loa Loa (eye worm) 26S protease regulatory subunit 8 0.0022 0.0009 0.0009
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0064 0.0331 0.033
Loa Loa (eye worm) proteasome subunit beta type 1 0.0517 0.3815 0.3815
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0246 0.173 0.173
Onchocerca volvulus 0.0023 0.0014 0.0015
Plasmodium vivax proteasome subunit beta type-5, putative 0.1322 1 1
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.0489 0.3594 0.3594
Leishmania major proteasome beta 2 subunit, putative 0.0314 0.2251 0.225
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0263 0.1861 0.1861
Toxoplasma gondii adhesion regulating molecule region protein, putative 0.0413 0.3008 0.3002
Echinococcus multilocularis cathepsin b 0.0063 0.0324 0.0324
Loa Loa (eye worm) carbonic anhydrase 3 0.0088 0.0517 0.0516
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0328 0.2361 0.2361
Echinococcus granulosus cathepsin b 0.0063 0.0324 0.0324
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0009 0.0009
Trichomonas vaginalis cop9 signalosome complex subunit, putative 0.0038 0.0127 0.0126
Plasmodium falciparum 26S proteasome regulatory subunit RPN13, putative 0.0215 0.1489 0.1481
Loa Loa (eye worm) proteasome Regulatory Particle 0.0038 0.0127 0.0126
Leishmania major proteasome alpha 2 subunit, putative 0.0278 0.197 0.197
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0009 0.0009
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0023 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0063 0.0322 0.0322
Entamoeba histolytica proteasome regulatory subunit, putative 0.0035 0.0102 0.0102
Trichomonas vaginalis 26S proteasome regulatory subunit rpn1, putative 0.0023 0.0012 0.0011
Toxoplasma gondii proteasome beta subunit 0.0265 0.1875 0.1868
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0322 0.0322
Toxoplasma gondii 26s proteasome subunit p55, putative 0.0038 0.0128 0.0119
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0322 0.0322
Plasmodium falciparum 26S protease regulatory subunit 6B, putative 0.0023 0.0014 0.0005
Echinococcus granulosus proteasome subunit beta type 6 0.0272 0.193 0.193
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0009 0.0009
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0274 0.1941 0.1941
Plasmodium falciparum 26S proteasome regulatory subunit RPN12, putative 0.0033 0.009 0.0081
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.0396 0.0396
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0285 0.2027 0.2027
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0285 0.2027 0.2027
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0285 0.2027 0.202
Loa Loa (eye worm) trypsin family protein 0.0063 0.0322 0.0322
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0322 0.0322
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0033 0.009 0.009
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0517 0.3815 0.3815
Schistosoma mansoni carbonic anhydrase-related 0.0033 0.0089 0.0089
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.0571 0.0571
Leishmania major proteasome alpha 7 subunit, putative 0.0274 0.1941 0.1941
Schistosoma mansoni hypothetical protein 0.0061 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0246 0.173 0.1729
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 4 0.0024 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0063 0.0322 0.0322
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0328 0.2361 0.2361
Brugia malayi Trypsin family protein 0.0063 0.0322 0.0322
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0285 0.2027 0.2027
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0272 0.1926 0.1926
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0038 0.0127 0.0126
Echinococcus granulosus carbonic anhydrase 0.0033 0.0089 0.0089
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0265 0.1875 0.1875
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0272 0.1926 0.1919
Echinococcus multilocularis carbonic anhydrase 0.0033 0.0089 0.0089
Onchocerca volvulus 0.0063 0.0322 0.0874
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0274 0.1941 0.1941
Brugia malayi steroid hormone receptor 0.0022 0.0009 0.0009
Echinococcus multilocularis glycoprotein Antigen 5 0.0063 0.0322 0.0322
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0352 0.0351
Trichomonas vaginalis 26S protease regulatory subunit 6A, putative 0.0023 0.0014 0.0014
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0272 0.193 0.193
Echinococcus multilocularis mitogen activated protein kinase 3 0.006 0.0296 0.0296
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0314 0.2251 0.2244
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0033 0.0089 0.0089
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0272 0.1926 0.1926
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0009 0.0009
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0263 0.1861 0.1861
Entamoeba histolytica 19S cap proteasome S2 subunit 0.0024 0.0019 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0059 0.0059
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 8 0.0033 0.009 0.009
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0009 0.0009
Schistosoma mansoni carbonic anhydrase 0.0033 0.0089 0.0089
Schistosoma mansoni ankyrin 23/unc44 0.0039 0.0133 0.0133
Leishmania major proteasome regulatory non-ATP-ase subunit 5, putative,19S proteasome regulatory subunit 0.0038 0.0128 0.0127
Loa Loa (eye worm) PAS-3 protein 0.0253 0.1783 0.1783
Echinococcus granulosus carbonic anhydrase II 0.0088 0.0517 0.0517
Trypanosoma cruzi 26S protease regulatory subunit, putative 0.0022 0.0009 0.0009
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0265 0.1875 0.1875
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0278 0.197 0.1963
Brugia malayi Ubiquitin interaction motif family protein 0.0024 0.0024 0.0024
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 7 0.0038 0.0127 0.0126
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0059 0.0059
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0063 0.0324 0.0324
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0396 0.0396
Schistosoma mansoni carbonic anhydrase-related 0.0033 0.0089 0.0089
Brugia malayi 20S proteasome alpha5 subunit 0.0285 0.2027 0.2027
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0022 0.0003 0.0002
Echinococcus granulosus gamma secretase subunit aph 1 0.0108 0.0664 0.0664
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 7 0.0035 0.0104 0.0104
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 9, putative 0.0035 0.0102 0.0102
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0009 0.0009
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0009 0.0009
Onchocerca volvulus 0.0229 0.1599 0.4436
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 3 0.0045 0.0181 0.0181
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.006 0.0296 0.0296
Plasmodium falciparum 26S proteasome regulatory subunit RPN9, putative 0.0035 0.0102 0.0093
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0064 0.0331 0.033
Toxoplasma gondii peptidase, T1 family protein 0.0274 0.1941 0.1934
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0089
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0253 0.1785 0.1785
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0035 0.0104 0.0104
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0265 0.1875 0.1875
Echinococcus granulosus adhesion regulating molecule 1 0.0413 0.3008 0.3008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0571 0.0571
Echinococcus granulosus mitogen activated protein kinase 3 0.006 0.0296 0.0296
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0045 0.0181 0.0181
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0272 0.193 0.193
Loa Loa (eye worm) hypothetical protein 0.0048 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0033 0.0089 0.0089
Plasmodium falciparum proteasome subunit beta type-5 0.1322 1 1
Schistosoma mansoni 26S proteasome subunit S9 0.0042 0.0157 0.0157
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.006 0.0296 0.0296
Schistosoma mansoni hypothetical protein 0.02 0.1376 0.1376
Plasmodium vivax 26S proteasome regulatory subunit RPN2, putative 0.0036 0.011 0.0101
Loa Loa (eye worm) hypothetical protein 0.0063 0.0322 0.0322
Brugia malayi Proteasome/cyclosome repeat family protein 0.003 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0063 0.0322 0.0322
Toxoplasma gondii heat shock protein hslv, putative 0.0235 0.1641 0.1634
Trypanosoma brucei Aph-1 protein, putative 0.0042 0.0159 0.0159
Onchocerca volvulus 0.0063 0.0322 0.0874
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 8 0.0033 0.009 0.009
Toxoplasma gondii SAC3/GANP family protein 0.0033 0.009 0.0081
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0035 0.0104 0.0104
Giardia lamblia Hypothetical protein 0.0042 0.0157 0.0157
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.006 0.0296 0.0296
Brugia malayi Proteasome subunit alpha type 7-1 0.0328 0.2361 0.2361
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0009 0.0008
Giardia lamblia 20S proteasome alpha subunit 1 0.0286 0.2035 0.2035
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0272 0.1926 0.1926
Brugia malayi 26S protease regulatory subunit 6A 0.0024 0.0025 0.0025
Plasmodium falciparum 26S protease regulatory subunit 6A, putative 0.0024 0.0025 0.0016
Brugia malayi Uncoordinated protein 44 0.0039 0.0133 0.0133
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0271 0.1922 0.1915
Leishmania major carbonic anhydrase-like protein 0.0088 0.0517 0.0516
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0272 0.1926 0.1926
Echinococcus multilocularis 26s proteasome regulatory particle subunit 0.0047 0.0194 0.0194
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0517 0.3815 0.3815
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0009 0.0008
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0272 0.1926 0.1926
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0022 0.0009 0.0009
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0263 0.1861 0.1861
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0009 0.0009
Onchocerca volvulus 0.0063 0.0322 0.0874
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0009 0.0009
Plasmodium vivax proteasome subunit beta type-6, putative 0.0272 0.193 0.1923
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0161 0.0161
Loa Loa (eye worm) proteasome subunit beta type 3 0.0265 0.1875 0.1875
Echinococcus multilocularis 26S proteasome regulatory subunit S3 0.0045 0.0181 0.0181
Toxoplasma gondii proteasome 26S regulatory subunit 0.0024 0.0019 0.001
Trypanosoma cruzi 19S proteasome regulatory subunit 0.0022 0.0009 0.0009
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 11, putative 0.0022 0.0003 0.0002
Echinococcus multilocularis 26S proteasome regulatory subunit N1 0.0035 0.0102 0.0102
Entamoeba histolytica proteasome regulatory subunit, putative 0.0045 0.0181 0.0181
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.0571 0.0571
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0009 0.0009
Giardia lamblia Proteasome subunit beta type 1 0.0517 0.3815 0.3815
Plasmodium falciparum 26S proteasome regulatory subunit p55, putative 0.0038 0.0128 0.0119
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0009 0.0009
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0022 0.0003 0.0003
Brugia malayi PCI domain containing protein 0.0038 0.0128 0.0128
Schistosoma mansoni hypothetical protein 0.0063 0.0322 0.0322
Giardia lamblia 26S proteasome regulatory subunit, putative 0.0023 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Trichomonas vaginalis 26S protease regulatory subunit S10b, putative 0.0022 0.0009 0.0009
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0022 0.0003 0.0002
Leishmania major proteasome alpha 3 subunit, putative 0.0272 0.1926 0.1926
Echinococcus multilocularis carbonic anhydrase II 0.0088 0.0517 0.0517
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0265 0.1875 0.1875
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0322 0.0322
Brugia malayi Probable 26S protease regulatory subunit 4 0.0023 0.0014 0.0014
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0009 0.0009
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.009 0.009
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0263 0.1861 0.1861
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0024 0.0025 0.0025
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0285 0.2027 0.2027
Leishmania major 26S protease regulatory subunit, putative,serine peptidase, Clan SJ, family S16, putative 0.0022 0.0009 0.0009
Loa Loa (eye worm) RPN-3 protein 0.0045 0.0181 0.0181
Leishmania major proteasome alpha 1 subunit, putative 0.0286 0.2035 0.2035
Echinococcus multilocularis mitogen activated protein kinase 0.006 0.0296 0.0296
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0274 0.1941 0.1941
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0286 0.2035 0.2035
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0272 0.193 0.193
Loa Loa (eye worm) hypothetical protein 0.003 0.0071 0.007
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0272 0.1926 0.1926
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0322 0.0322
Plasmodium vivax 26S proteasome regulatory subunit RPN12, putative 0.0033 0.009 0.0081
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0285 0.2027 0.202
Toxoplasma gondii 26s proteasome regulatory complex subunit, putative 0.0038 0.0127 0.0118
Giardia lamblia Kinase, CMGC MAPK 0.006 0.0296 0.0296
Loa Loa (eye worm) proteasome subunit beta type 2 0.031 0.2217 0.2217
Schistosoma mansoni lozenge 0.0061 0.0308 0.0308
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0009 0.0009
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0088 0.0517 0.0516
Plasmodium vivax 26S protease regulatory subunit 4, putative 0.0023 0.0014 0.0005
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0088 0.0517 0.0516
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0009 0.0008
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0286 0.2035 0.2035
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0047 0.0194 0.0194
Leishmania major proteasome regulatory non-ATPase subunit, putative 0.0047 0.0194 0.0194
Brugia malayi Trypsin-like protease protein 5 0.0063 0.0322 0.0322
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0063 0.0324 0.0324
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0059 0.0059
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0009 0.0009
Echinococcus granulosus glycoprotein Antigen 5 0.0063 0.0322 0.0322
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0035 0.0104 0.0104
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0278 0.197 0.1963
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0352 0.0352
Echinococcus multilocularis proteasome subunit beta type 7 0.0893 0.6706 0.6706
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0265 0.1875 0.1875
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0059 0.005
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0036 0.011 0.011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0009 0.0009
Echinococcus granulosus microtubule associated protein 2 0.0761 0.569 0.569
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 9 0.0035 0.0102 0.0102
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0063 0.0322 0.0322
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0022 0.0003 0.0002
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0024 0.0025 0.0025
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0296 0.0296
Plasmodium falciparum proteasome subunit beta type-4 0.0263 0.1861 0.1853
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0322 0.0322
Schistosoma mansoni hypothetical protein 0.0033 0.0089 0.0089
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0517 0.3815 0.3809
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0271 0.1922 0.1915
Plasmodium falciparum carbonic anhydrase 0.0033 0.0089 0.008
Leishmania major proteasome beta-1 subunit, putative 0.0272 0.193 0.193
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0272 0.1926 0.1926
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0014
Echinococcus granulosus Mastin 0.0063 0.0322 0.0322
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0272 0.1926 0.1926
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0263 0.1861 0.1861
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0328 0.2361 0.2361
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0263 0.1861 0.1861
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0322 0.0322
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0263 0.1861 0.1853
Toxoplasma gondii Mov34/MPN/PAD-1 family protein 0.0035 0.0104 0.0095
Echinococcus multilocularis proteasome subunit alpha type 2 0.0278 0.197 0.197
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0571 0.0571
Plasmodium vivax proteasome subunit beta type-2, putative 0.031 0.2217 0.221
Loa Loa (eye worm) 26S proteasome non-ATPase regulatory subunit 7 0.0035 0.0104 0.0104
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0024 0.0024 0.0024
Plasmodium vivax 26S proteasome regulatory subunit p55, putative 0.0038 0.0128 0.0119
Loa Loa (eye worm) hypothetical protein 0.0039 0.0134 0.0134
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1322 1 1
Brugia malayi Trypsin family protein 0.0063 0.0322 0.0322
Echinococcus granulosus DSS1 SEM1 domain containing protein 0.01 0.0608 0.0608
Plasmodium vivax proteasome subunit beta type-3, putative 0.0265 0.1875 0.1868
Echinococcus multilocularis proteasome (prosome, macropain) 0.1322 1 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0322 0.0322
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0009 0.0009
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0285 0.2027 0.2027
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0063 0.0322 0.0322
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0009 0.0009
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0285 0.2027 0.2027
Toxoplasma gondii PCI domain-containing protein 0.0045 0.0181 0.0173
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0266 0.1883 0.1883
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0009 0.0009
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0022 0.0003 0.0002
Brugia malayi 26S protease regulatory subunit 8 0.0022 0.0009 0.0009
Giardia lamblia 26S proteasome ATPase subunit S4, putative 0.0023 0.0014 0.0014
Echinococcus granulosus 26S proteasome regulatory subunit S3 0.0045 0.0181 0.0181
Brugia malayi proteasome subunit beta type 1 0.0517 0.3815 0.3815
Trypanosoma brucei proteasome beta 7 subunit 0.0263 0.1861 0.1861
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.0396 0.0396
Schistosoma mansoni hypothetical protein 0.0035 0.0102 0.0102
Echinococcus granulosus proteasome prosome macropain subunit beta 0.031 0.2217 0.2217
Giardia lamblia 26S protease regulatory subunit 6B 0.0023 0.0014 0.0014
Giardia lamblia 26S protease regulatory subunit 6A 0.0024 0.0025 0.0024
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0571 0.0571
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0263 0.1861 0.1861
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0272 0.193 0.193
Echinococcus multilocularis Mastin 0.0063 0.0322 0.0322
Trichomonas vaginalis proteasome regulatory subunits, putative 0.0038 0.0128 0.0127
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.0035 0.0104 0.0104
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0035 0.0104 0.0095
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 7 0.0022 0.0003 0.0002
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0285 0.2027 0.2027
Plasmodium falciparum 26S proteasome regulatory subunit RPN6 0.0042 0.0157 0.0148
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0207 0.0207
Trypanosoma brucei proteasome beta 6 subunit 0.0517 0.3815 0.3815
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 2 0.0047 0.0194 0.0194
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0023 0.0014 0.0014
Brugia malayi Pre-SET motif family protein 0.0201 0.1384 0.1384
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0235 0.1641 0.5
Echinococcus multilocularis proteasome 26s subunit subunit 4 atpase 0.0023 0.0014 0.0014
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0063 0.0324 0.0324
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 4 0.0024 0.0024 0.0024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0133 0.0133
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0571 0.0571
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 6 0.0038 0.0127 0.0127
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0271 0.1922 0.1922
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0278 0.197 0.1963
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 6 0.0038 0.0127 0.0126
Brugia malayi Proteasome A-type and B-type family protein 0.0263 0.1861 0.1861
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0009 0.0008
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0063 0.0322 0.0322
Brugia malayi Adhesion regulating molecule conserved region family protein 0.0413 0.3008 0.3008
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0328 0.2361 0.2361
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0314 0.2251 0.225
Loa Loa (eye worm) hypothetical protein 0.0063 0.0322 0.0322
Echinococcus granulosus nuclear factor of activated T cells 5 0.0377 0.2737 0.2737
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 7 0.0035 0.0104 0.0104
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.0023 0.0014 0.0014
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.006 0.0296 0.0287
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0328 0.2361 0.2361
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0009 0.0009
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0235 0.1641 0.1634
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0009 0.0009
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0035 0.0104 0.0104
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0352 0.0351
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0286 0.2035 0.2035
Brugia malayi proteasome subunit beta type 2 0.031 0.2217 0.2217
Echinococcus granulosus Proteasome subunit alpha beta 0.0274 0.1941 0.1941
Echinococcus multilocularis proteasome subunit alpha type 6 0.0286 0.2035 0.2035
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0009 0.0009
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0201 0.1384 0.1384
Loa Loa (eye worm) hypothetical protein 0.0063 0.0322 0.0322
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0314 0.2251 0.2251
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0022 0.0009 0.0009
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.031 0.2217 0.2217
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.031 0.2217 0.2217
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0033 0.0089 0.0089
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0207 0.0207
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1322 1 1
Echinococcus granulosus death domain containing protein 0.0039 0.0133 0.0133
Leishmania major proteasome beta 7 subunit, putative 0.0263 0.1861 0.1861
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0314 0.2251 0.225
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0328 0.2361 0.2361
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0352 0.0343
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0517 0.3815 0.3815
Echinococcus multilocularis proteasome subunit beta type 6 0.0272 0.193 0.193
Echinococcus granulosus 26s proteasome regulatory particle subunit 0.0047 0.0194 0.0194
Brugia malayi proteasome subunit beta type 3 0.0265 0.1875 0.1875
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.0035 0.0104 0.0104
Echinococcus multilocularis transmembrane protease serine 3 0.0063 0.0322 0.0322
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0265 0.1875 0.1868
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0235 0.1641 0.1641
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0088 0.0517 0.0517
Brugia malayi 26S proteasome regulatory complex subunit p97 0.0047 0.0194 0.0194
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0322 0.0322
Loa Loa (eye worm) hypothetical protein 0.0033 0.009 0.009
Loa Loa (eye worm) 26S protease regulatory subunit 6A 0.0024 0.0025 0.0024
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0259 0.1827 0.1827
Schistosoma mansoni netrin receptor unc5 0.0039 0.0133 0.0133
Echinococcus granulosus mitogen activated protein kinase 0.006 0.0296 0.0296
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0322 0.0322
Plasmodium falciparum 26S proteasome regulatory subunit RPN2, putative 0.0036 0.011 0.0101
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0396 0.0396
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0023 0.0014 0.0014
Trypanosoma brucei carbonic anhydrase-like protein 0.0088 0.0517 0.0516
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0033 0.0089 0.0089
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.0064 0.0331 0.033
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0296 0.0296
Echinococcus granulosus subfamily T1A non peptidase ue 0.0285 0.2027 0.2027
Brugia malayi proteasome subunit alpha type 2 0.0278 0.197 0.197
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0088 0.0517 0.0517
Schistosoma mansoni hypothetical protein 0.02 0.1376 0.1376
Brugia malayi nuclear receptor NHR-88 0.0022 0.0009 0.0009
Entamoeba histolytica proteasome regulatory subunit, putative 0.0033 0.009 0.009
Echinococcus granulosus 26s protease regulatory subunit 6a 0.0024 0.0025 0.0025
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 7, putative 0.0038 0.0127 0.0126
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0009 0.0009
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0047 0.0194 0.0194
Plasmodium vivax 26S proteasome regulatory subunit RPN6, putative 0.0042 0.0157 0.0148
Giardia lamblia 20S proteasome alpha subunit 7 0.0274 0.1941 0.1941
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0063 0.0322 0.0322
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0278 0.197 0.197
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0024 0.0024 0.0024
Plasmodium falciparum proteasome subunit beta type-2, putative 0.031 0.2217 0.221
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0259 0.1827 0.1827
Brugia malayi Proteasome subunit alpha type 1 0.0253 0.1779 0.1779
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0088 0.0517 0.0516
Trypanosoma brucei proteasome subunit beta type-2, putative 0.031 0.2217 0.2217
Brugia malayi nuclear hormone receptor 0.0022 0.0009 0.0009
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0285 0.2027 0.2027
Toxoplasma gondii proteasome subunit beta type 2, putative 0.031 0.2217 0.221
Echinococcus multilocularis Protein lozenge 0.0061 0.0308 0.0308
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0286 0.2035 0.2028
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0271 0.1922 0.1915
Plasmodium falciparum 26S protease regulatory subunit 4, putative 0.0023 0.0014 0.0005
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0272 0.193 0.193
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.031 0.2217 0.2217
Echinococcus multilocularis carbonic anhydrase 0.0033 0.0089 0.0089
Trichomonas vaginalis set domain proteins, putative 0.0229 0.1598 0.1598
Loa Loa (eye worm) RPT-2 protein 0.0023 0.0014 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0296 0.0296
Entamoeba histolytica hypothetical protein 0.0036 0.011 0.011
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0263 0.1861 0.1861
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0009 0.0009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0352 0.0351
Echinococcus multilocularis carbonic anhydrase 0.0033 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0039 0.0133 0.0133
Schistosoma mansoni proteasome regulatory subunit-related 0.0038 0.0128 0.0128
Echinococcus multilocularis DSS1 (SEM1) domain containing protein 0.01 0.0608 0.0608
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 5 0.0038 0.0128 0.0127
Schistosoma mansoni 26S proteasome regulatory subunit rpn2 0.0036 0.011 0.011
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0035 0.0104 0.0104
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 7 0.0035 0.0104 0.0104
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 6 0.0038 0.0127 0.0127
Echinococcus multilocularis cathepsin b 0.0063 0.0324 0.0324
Trypanosoma brucei protein kinase, putative 0.006 0.0296 0.0296
Giardia lamblia 20S proteasome alpha subunit 2 0.0278 0.197 0.197
Toxoplasma gondii PCI domain-containing protein 0.0035 0.0102 0.0093
Toxoplasma gondii proteasome subunit alpha type, putative 0.0094 0.0556 0.0548
Brugia malayi MAP kinase sur-1 0.006 0.0296 0.0296
Schistosoma mansoni adhesion regulating molecule 1 (110 kD cell membrane glycoprotein) 0.0413 0.3008 0.3008
Brugia malayi Proteasome A-type and B-type family protein 0.0893 0.6706 0.6706
Onchocerca volvulus 26S protease regulatory subunit 8 homolog 0.0022 0.0009 0.0001
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0328 0.2361 0.2354
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.006 0.0296 0.0296
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0271 0.1922 0.1922
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0009 0.0009
Toxoplasma gondii 26S proteasome regulatory subunit, S6a family AAA ATpase 0.0024 0.0025 0.0016
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0265 0.1875 0.1875
Giardia lamblia 20S proteasome alpha subunit 4 0.0328 0.2361 0.2361
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0296 0.0296
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0024 0.0025 0.0024
Plasmodium falciparum 26S proteasome regulatory subunit RPN7, putative 0.0038 0.0127 0.0118
Echinococcus granulosus proteasome subunit alpha type 6 0.0286 0.2035 0.2035
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0009 0.0009
Plasmodium vivax 26S proteasome AAA-ATPase subunit RPT3, putative 0.0023 0.0014 0.0005
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.0023 0.0014 0.0014
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0045 0.0181 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0009 0.0009
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0278 0.197 0.197
Trichomonas vaginalis 26S proteasome regulatory subunit S3, putative 0.0024 0.0024 0.0024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0059 0.0059
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0235 0.1641 0.1634
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0108 0.0664 0.0664
Echinococcus multilocularis gamma secretase subunit aph 1 0.0108 0.0664 0.0664
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0039 0.0133 0.0133
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0035 0.0104 0.0095
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0274 0.1941 0.1934
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 3 0.0045 0.0181 0.0181
Leishmania major hypothetical protein, conserved 0.0215 0.1489 0.1488
Loa Loa (eye worm) hypothetical protein 0.0489 0.3594 0.3594
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0322 0.0322
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.006 0.0296 0.0296
Onchocerca volvulus Proteasomal ubiquitin receptor ADRM1 homolog 0.0262 0.185 0.5137
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0396 0.0396
Toxoplasma gondii proteasome subunit alpha type, putative 0.0272 0.1926 0.1919
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0274 0.1941 0.1941
Echinococcus multilocularis 26s protease regulatory subunit s10b 0.0022 0.0009 0.0009
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0285 0.2027 0.2027
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0285 0.2027 0.202
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0274 0.1941 0.1941
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Brugia malayi gamma-secretase subunit aph-1 0.0108 0.0664 0.0664
Trypanosoma brucei proteasome subunit beta type-5, putative 0.1322 1 1
Giardia lamblia 20S proteasome alpha subunit 3 0.0272 0.1926 0.1926
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 2 0.0036 0.011 0.011
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0009 0.0009
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0023 0.0014 0.0014
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0322 0.0322
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.0396 0.0396
Loa Loa (eye worm) PCI domain-containing protein 0.0035 0.0102 0.0102
Leishmania major proteasome regulatory non-ATP-ase subunit 3, putative 0.0045 0.0181 0.0181
Echinococcus granulosus enteropeptidase 0.0063 0.0322 0.0322
Plasmodium vivax proteasome subunit beta type-7, putative 0.0314 0.2251 0.2244
Brugia malayi 26S proteasome non-ATPase regulatory subunit 7, putative 0.0035 0.0104 0.0104
Plasmodium vivax 26S proteasome regulatory subunit RPN1, putative 0.0047 0.0194 0.0185
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0286 0.2035 0.2035
Trypanosoma brucei Regulatory particle triple-A ATPase subunit 6 0.0022 0.0009 0.0009
Plasmodium falciparum 26S proteasome regulatory subunit RPN3, putative 0.0045 0.0181 0.0173
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0088 0.0517 0.0517
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0517 0.3815 0.3815
Echinococcus multilocularis 26s protease regulatory subunit 6a 0.0024 0.0025 0.0025
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0023 0.0014 0.0014
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0235 0.1641 0.1641
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0328 0.2361 0.2361
Loa Loa (eye worm) proteasome 26S subunit 0.0022 0.0003 0.0002
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.0396 0.0396
Trypanosoma cruzi 20S proteasome subunit 0.031 0.2217 0.2217
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0286 0.2035 0.2035
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0263 0.1861 0.1861
Loa Loa (eye worm) hypothetical protein 0.0341 0.2461 0.2461
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0272 0.193 0.193
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.1322 1 1
Echinococcus granulosus proteasome prosome macropain 0.1322 1 1
Brugia malayi Trypsin family protein 0.0063 0.0322 0.0322
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0022 0.0009 0.0009
Echinococcus granulosus 26S proteasome regulatory subunit T3 0.0023 0.0014 0.0014
Leishmania major proteasome regulatory non-ATPase subunit 6, putative 0.0042 0.0157 0.0157
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0263 0.1861 0.1861
Trypanosoma brucei proteasome regulatory ATPase subunit 3 0.0023 0.0014 0.0014
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0274 0.1941 0.1941
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0035 0.0104 0.0104
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0322 0.0322
Loa Loa (eye worm) hypothetical protein 0.0063 0.0322 0.0322
Loa Loa (eye worm) runx1 0.0061 0.0308 0.0308
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0274 0.1941 0.1934
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 7, putative 0.0034 0.0095 0.0095
Onchocerca volvulus 0.0489 0.3594 1
Echinococcus granulosus proteasome subunit alpha type 2 0.0278 0.197 0.197
Entamoeba histolytica proteasome regulatory subunit, putative 0.0038 0.0127 0.0127
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0033 0.009 0.009
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0024 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0009
Plasmodium vivax SET domain protein, putative 0.0029 0.0059 0.005
Echinococcus granulosus Proteasome subunit alpha type 7 0.0328 0.2361 0.2361
Leishmania major proteasome regulatory non-ATP-ase subunit 8, putative,26S proteasome regulatory subunit, putative 0.0035 0.0104 0.0104
Schistosoma mansoni cercarial elastase (S01 family) 0.0063 0.0322 0.0322
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0271 0.1922 0.1922
Brugia malayi Pre-SET motif family protein 0.0029 0.0059 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.0008
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0272 0.1926 0.1926
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0278 0.197 0.197
Brugia malayi ecdysteroid receptor 0.0022 0.0009 0.0009
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.0396 0.0396
Echinococcus granulosus carbonic anhydrase 0.0033 0.0089 0.0089
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0235 0.1641 0.1641
Brugia malayi Proteasome regulatory particle, non-atpase-like protein 6 0.0042 0.0157 0.0157
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0235 0.1645 0.1645
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0286 0.2035 0.2035
Echinococcus multilocularis adhesion regulating molecule 1 0.0413 0.3008 0.3008
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0235 0.1641 0.1641
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0009 0.0009
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0009 0.0009
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit, putative 0.0035 0.0104 0.0104
Trypanosoma brucei 26S proteasome regulatory non-ATPase subunit 0.0047 0.0194 0.0194
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0272 0.193 0.193
Leishmania major proteasome regulatory ATPase subunittcc1l8.3, putative 0.0023 0.0014 0.0014
Echinococcus multilocularis Ankyrin 0.0039 0.0134 0.0134

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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