Detailed information for compound 1174424

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 254.301 | Formula: C9H18O6S
  • H donors: 6 H acceptors: 6 LogP: -2.56 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-]C[C@H]([C@H](C[S@@+]1C[C@H]([C@@H]([C@H]1CO)O)O)O)O
  • InChi: 1S/C9H18O6S/c10-1-5(12)6(13)3-16-4-7(14)9(15)8(16)2-11/h5-9,11-15H,1-4H2/t5-,6+,7-,8-,9+,16-/m1/s1
  • InChiKey: FYDHJNVIWCDSTE-XUKXIEPXSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi GCC2 and GCC3 family protein 0.0027 0.0126 0.013
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0126 0.1268 0.2337
Toxoplasma gondii Amylo-alpha-1,6-glucosidase 0.0157 0.1618 0.2982
Schistosoma mansoni slit 0.0027 0.0126 0.0126
Echinococcus multilocularis peregrin 0.0094 0.0898 0.1656
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Plasmodium vivax hypothetical protein, conserved 0.0093 0.0882 0.1463
Echinococcus multilocularis chromobox protein 1 0.0154 0.1584 0.2919
Echinococcus multilocularis Chromobox protein 3 0.0025 0.0103 0.0189
Brugia malayi hypothetical protein 0.0025 0.0103 0.0106
Trypanosoma brucei glucosidase, putative 0.0082 0.0755 0.0951
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0294 0.0348
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.0027 0.0049
Echinococcus multilocularis tissue type plasminogen activator 0.0191 0.2014 0.3712
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0126 0.1268 0.2282
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.003 0.0162 0.0299
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Onchocerca volvulus 0.0073 0.0653 0.0592
Schistosoma mansoni phd/f-box containing protein 0.003 0.0158 0.0158
Brugia malayi Calcitonin receptor-like protein seb-1 0.0194 0.2051 0.2113
Treponema pallidum fructose-bisphosphate aldolase 0.0322 0.3524 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0107 0.011
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0101 0.0973 0.0973
Echinococcus granulosus neurogenic locus notch protein 0.0027 0.0126 0.0232
Schistosoma mansoni hypothetical protein 0.0061 0.0521 0.0521
Echinococcus multilocularis tumor protein p63 0.0241 0.2594 0.478
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0053 0.0428 0.0428
Onchocerca volvulus 0.0047 0.0355 0.0281
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0027 0.0126 0.0126
Trypanosoma brucei hypothetical protein, conserved 0.0704 0.7935 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0026 0.011 0.0203
Echinococcus granulosus histone lysine methyltransferase setb 0.0095 0.0908 0.1673
Plasmodium falciparum glutathione reductase 0.0038 0.0251 0.0462
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0039 0.0262 0.033
Entamoeba histolytica hypothetical protein 0.0025 0.0103 0.0189
Trichomonas vaginalis hypothetical protein 0.0025 0.0103 0.0121
Mycobacterium leprae Probable lipase LipE 0.0073 0.0653 0.3583
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0082 0.0755 0.1391
Brugia malayi MH2 domain containing protein 0.0098 0.0941 0.0969
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0002 0.0003
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0189
Loa Loa (eye worm) hypothetical protein 0.0069 0.0611 0.063
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.003 0.0158 0.0291
Echinococcus granulosus delta-like protein 1 0.0027 0.0126 0.0232
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0377 0.0388
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0002
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0882 0.1625
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0355 0.0366
Toxoplasma gondii histone lysine methyltransferase SET1 0.0049 0.0384 0.0707
Trichomonas vaginalis Heterochromatin protein, putative 0.0025 0.0103 0.0121
Schistosoma mansoni protein phosphatase 2C 0.003 0.0158 0.0158
Echinococcus granulosus chromobox protein 2 0.0025 0.0103 0.0189
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0027 0.0126 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0653 0.0823
Echinococcus granulosus jumonji domain containing protein 0.0129 0.13 0.2396
Echinococcus multilocularis Chromo domain 0.0025 0.0103 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0487 0.5427 1
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.003 0.0158 0.0199
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0096 0.0923 0.5365
Brugia malayi hypothetical protein 0.023 0.2471 0.2546
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0047 0.036 0.0663
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Schistosoma mansoni hypothetical protein 0.003 0.0162 0.0162
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0037 0.0236 0.0436
Loa Loa (eye worm) latrophilin receptor protein 2 0.0061 0.0521 0.0537
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.003 0.0158 0.0199
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0049 0.0377 0.0694
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Brugia malayi F/Y-rich N-terminus family protein 0.0041 0.0285 0.0294
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0103 0.0189
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0044 0.0322 0.0592
Loa Loa (eye worm) hypothetical protein 0.0857 0.9706 1
Brugia malayi hypothetical protein 0.0035 0.0218 0.0225
Echinococcus granulosus tissue type plasminogen activator 0.0191 0.2014 0.3712
Brugia malayi Pre-SET motif family protein 0.0095 0.0908 0.0936
Brugia malayi jmjC domain containing protein 0.0303 0.3314 0.3414
Schistosoma mansoni hypothetical protein 0.0061 0.0521 0.0521
Schistosoma mansoni hypothetical protein 0.0335 0.3678 0.3678
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0026 0.011 0.5
Echinococcus granulosus slit 2 protein 0.0027 0.0126 0.0232
Echinococcus multilocularis GPCR, family 2 0.0061 0.0521 0.096
Brugia malayi Pre-SET motif family protein 0.0659 0.7413 0.7638
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0191 0.2014 0.3591
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0138
Brugia malayi SEA domain containing protein 0.0069 0.0611 0.063
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Loa Loa (eye worm) PHD-finger family protein 0.0093 0.0882 0.0908
Echinococcus multilocularis neuropeptide receptor A26 0.0381 0.4205 0.7748
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.1794
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0653 0.107
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0158 0.0163
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Schistosoma mansoni hypothetical protein 0.0133 0.1343 0.1343
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0653 0.0673
Echinococcus granulosus CREB binding protein 0.0051 0.0404 0.0744
Toxoplasma gondii ABC1 family protein 0.0073 0.0653 0.1204
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0158 0.0163
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0064 0.0551 0.1015
Onchocerca volvulus 0.0069 0.0611 0.0548
Echinococcus granulosus neuropeptide receptor A26 0.0381 0.4205 0.7748
Toxoplasma gondii calcium binding egf domain-containing protein 0.0071 0.0633 0.1167
Brugia malayi Protein kinase domain containing protein 0.0191 0.2014 0.2075
Echinococcus granulosus phd:f box containing protein 0.003 0.0158 0.0291
Echinococcus granulosus survival motor neuron protein 1 0.023 0.2471 0.4553
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0164 0.0194
Mycobacterium tuberculosis Conserved protein 0.0073 0.0653 0.107
Onchocerca volvulus 0.0069 0.0611 0.0548
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0037 0.0236 0.0244
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0103 0.0103
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0096 0.0923 0.1603
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Echinococcus granulosus glycoprotein Antigen 5 0.0101 0.0973 0.1794
Echinococcus multilocularis chromobox protein 1 0.0154 0.1584 0.2919
Schistosoma mansoni hypothetical protein 0.0061 0.0521 0.0521
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0087 0.0812 0.4629
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0236 0.0236
Brugia malayi M-phase phosphoprotein, mpp8 0.0025 0.0103 0.0106
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0908 0.0908
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0322 0.3524 0.6494
Trypanosoma brucei Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0136 0.016
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0659 0.7413 0.7638
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0095 0.0908 0.1673
Schistosoma mansoni voltage-gated potassium channel 0.007 0.0619 0.0619
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Echinococcus granulosus Chromobox protein 3 0.0025 0.0103 0.0189
Toxoplasma gondii thioredoxin reductase 0.0038 0.0251 0.0462
Schistosoma mansoni hypothetical protein 0.0101 0.0973 0.0973
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0026 0.011 0.0203
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0377 0.0445
Echinococcus granulosus lysosomal alpha glucosidase 0.0366 0.4037 0.7439
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0026 0.011 0.0014
Loa Loa (eye worm) CXXC zinc finger family protein 0.0024 0.0084 0.0087
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.0973
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Entamoeba histolytica hypothetical protein 0.0026 0.011 0.0203
Schistosoma mansoni phosphatidylserine receptor 0.003 0.0158 0.0158
Brugia malayi Cadherin domain containing protein 0.0027 0.0126 0.013
Loa Loa (eye worm) hypothetical protein 0.0047 0.036 0.0371
Loa Loa (eye worm) hypothetical protein 0.0157 0.1618 0.1668
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0087 0.0812 0.1383
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Schistosoma mansoni jumonji domain containing protein 0.0241 0.2594 0.2594
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0653 0.3583
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0091 0.0862 0.1588
Echinococcus multilocularis cpg binding protein 0.0025 0.01 0.0184
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0027
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0025 0.0103 0.0106
Loa Loa (eye worm) DOMON domain-containing protein 0.0069 0.0611 0.063
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.0027 0.0049
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0653 0.3583
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0027 0.0126 0.013
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0049 0.0377 0.0694
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0084 0.0782 0.0806
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0026 0.0118 0.0118
Loa Loa (eye worm) TK/ROR protein kinase 0.0191 0.2014 0.2075
Loa Loa (eye worm) hypothetical protein 0.0084 0.0782 0.0806
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0025 0.0103 0.0103
Echinococcus granulosus protein jagged 1 0.0027 0.0126 0.0232
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892
Loa Loa (eye worm) hypothetical protein 0.0067 0.0591 0.0609
Echinococcus multilocularis notch 0.0027 0.0126 0.0232
Plasmodium falciparum JmjC domain-containing protein, putative 0.003 0.0158 0.0291
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Loa Loa (eye worm) CBP-B 0.0058 0.0478 0.0492
Echinococcus granulosus neurogenic locus protein delta 0.0027 0.0126 0.0232
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0194 0.2051 0.2113
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0653 0.107
Leishmania major hypothetical protein, conserved 0.003 0.0158 0.0291
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0653 0.0772
Giardia lamblia 4-alpha-glucanotransferase, amylo-alpha-1,6-glucosidase 0.0157 0.1618 0.4593
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0158 0.0163
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Giardia lamblia PHD finger protein 15 0.0093 0.0882 0.2502
Plasmodium vivax JmjC domain containing protein 0.003 0.0158 0.0104
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Leishmania major hypothetical protein, conserved 0.0191 0.2014 0.3712
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0096 0.0923 0.1603
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0191 0.2014 0.2075
Brugia malayi TAZ zinc finger family protein 0.0083 0.0771 0.0794
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0025 0.0103 0.0189
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0082 0.0755 0.0892
Trichomonas vaginalis glycogen debranching enzyme, putative 0.0157 0.1618 0.1912
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0303 0.3314 0.6107
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0061 0.0521 0.096
Echinococcus multilocularis lysosomal alpha glucosidase 0.0366 0.4037 0.7439
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0047 0.036 0.0454
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0047 0.036 0.0287
Echinococcus multilocularis PHD finger protein rhinoceros 0.0093 0.0882 0.1625
Loa Loa (eye worm) jmjC domain-containing protein 0.0191 0.202 0.2081
Onchocerca volvulus 0.0073 0.0653 0.0592
Echinococcus multilocularis neurogenic locus protein delta 0.0027 0.0126 0.0232
Onchocerca volvulus 0.0092 0.0871 0.0818
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0653 0.107
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0061 0.0521 0.096
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0126 0.1268 0.2337
Echinococcus granulosus neural cadherin 0.0027 0.0126 0.0232
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0047 0.036 0.0454
Trichomonas vaginalis esterase, putative 0.0073 0.0653 0.0772
Echinococcus granulosus JmjC domain containing protein 4 0.003 0.0158 0.0291
Echinococcus granulosus protein jagged 2 0.0027 0.0126 0.0232
Echinococcus granulosus CREB binding protein 0.0083 0.0771 0.142
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0039 0.0262 0.0483
Echinococcus granulosus laminin 0.0071 0.0633 0.1167
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0487 0.5427 0.5591
Onchocerca volvulus 0.0025 0.0103 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0138
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0093 0.0882 0.0882
Loa Loa (eye worm) hypothetical protein 0.0133 0.1343 0.1383
Echinococcus granulosus dnaJ subfamily B 0.0335 0.3678 0.6778
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0083 0.0771 0.0771
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0037 0.0236 0.0436
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0095 0.0908 0.1673
Plasmodium falciparum cysteine repeat modular protein 1 0.0191 0.2014 0.3712
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Loa Loa (eye worm) hypothetical protein 0.0071 0.0633 0.0653
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Brugia malayi Calcium binding EGF domain containing protein 0.0027 0.0126 0.013
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.0377 0.0475
Echinococcus granulosus peregrin 0.0094 0.0898 0.1656
Echinococcus granulosus notch 0.0027 0.0126 0.0232
Brugia malayi Trypsin family protein 0.0101 0.0973 0.1003
Schistosoma mansoni hypothetical protein 0.0201 0.2134 0.2134
Echinococcus granulosus lysine specific demethylase 6a 0.003 0.0158 0.0291
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.0755 0.0951
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Trichomonas vaginalis set domain proteins, putative 0.075 0.8463 1
Trypanosoma cruzi target of rapamycin kinase 3 0.0039 0.0262 0.033
Brugia malayi CHD4 protein 0.0026 0.0118 0.0122
Plasmodium vivax SET domain protein, putative 0.0095 0.0908 0.1513
Brugia malayi Trypsin-like protease protein 5 0.0101 0.0973 0.1003
Onchocerca volvulus 0.0332 0.3642 0.3698
Brugia malayi beta-lactamase family protein 0.0073 0.0653 0.0673
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Schistosoma mansoni hypothetical protein 0.0061 0.0521 0.0521
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0179 0.0211
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0037 0.0236 0.0436
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Echinococcus granulosus glycogen debranching enzyme 0.0157 0.1618 0.2982
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0113 0.1122 0.1122
Toxoplasma gondii EGF family domain-containing protein 0.0027 0.0126 0.0232
Echinococcus multilocularis neurogenic locus notch protein 4 0.0027 0.0126 0.0232
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0908 0.0908
Trichomonas vaginalis maltase-glucoamylase, putative 0.0082 0.0755 0.0892
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Brugia malayi Glycosyl hydrolases family 31 protein 0.0047 0.036 0.0371
Onchocerca volvulus 0.0191 0.2014 0.2006
Brugia malayi Calcium binding EGF domain containing protein 0.0027 0.0126 0.013
Trichomonas vaginalis chromobox protein, putative 0.0154 0.1584 0.1872
Echinococcus multilocularis jumonji domain containing protein 0.0129 0.13 0.2396
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0232 0.0428
Loa Loa (eye worm) hypothetical protein 0.0039 0.0262 0.027
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0487 0.5427 0.5591
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0653 0.1204
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.011 0.0139
Giardia lamblia High cysteine protein 0.0027 0.0126 0.0357
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0087 0.0812 0.1383
Schistosoma mansoni egf-like domain protein 0.0071 0.0633 0.0633
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Echinococcus multilocularis glycoprotein Antigen 5 0.0101 0.0973 0.1794
Mycobacterium ulcerans lipase LipD 0.0073 0.0653 0.3583
Onchocerca volvulus 0.0073 0.0653 0.0592
Entamoeba histolytica hypothetical protein 0.0025 0.0103 0.0189
Brugia malayi jmjC domain containing protein 0.0113 0.1122 0.1156
Schistosoma mansoni hypothetical protein 0.0025 0.0103 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0806 0.0952
Leishmania major hypothetical protein, conserved 0.0073 0.0653 0.1204
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0095 0.0908 0.1673
Loa Loa (eye worm) hypothetical protein 0.0857 0.9706 1
Brugia malayi latrophilin 2 splice variant baaae 0.0133 0.1343 0.1383
Mycobacterium tuberculosis Probable reductase 0.0087 0.0812 0.1383
Schistosoma mansoni cell polarity protein 0.0027 0.0126 0.0126
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0653 0.107
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Echinococcus multilocularis neural cadherin 0.0027 0.0126 0.0232
Brugia malayi chromobox protein homolog 3 0.0086 0.0806 0.083
Brugia malayi beta-lactamase family protein 0.0073 0.0653 0.0673
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0093 0.0881 0.0828
Echinococcus multilocularis enteropeptidase 0.0101 0.0973 0.1794
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0084 0.0779 0.0802
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0487 0.5427 1
Giardia lamblia GTOR 0.0049 0.0377 0.1069
Onchocerca volvulus 0.0035 0.022 0.0141
Brugia malayi PHD-finger family protein 0.0032 0.0178 0.0183
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0139
Echinococcus multilocularis slit 2 protein 0.0027 0.0126 0.0232
Loa Loa (eye worm) heterochromatin protein 1 0.0154 0.1584 0.1632
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.0973
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0487 0.5427 0.6839
Brugia malayi Heterochromatin protein 1 0.0154 0.1584 0.1632
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0251 0.0277
Echinococcus granulosus lysine specific demethylase 5A 0.0113 0.1122 0.2068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0138
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0061 0.0521 0.096
Loa Loa (eye worm) hypothetical protein 0.023 0.2471 0.2546
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0049 0.0377 0.0694
Schistosoma mansoni septate junction protein 0.0027 0.0126 0.0126
Leishmania major glycosyl hydrolase-like protein 0.0047 0.036 0.0663
Loa Loa (eye worm) hypothetical protein 0.0093 0.0882 0.0908
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.1268 0.1268
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Schistosoma mansoni hypothetical protein 0.0191 0.2014 0.2014
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0082 0.0755 0.0892
Brugia malayi Kringle domain containing protein 0.0191 0.2014 0.2075
Giardia lamblia Fructose-bisphosphate aldolase 0.0322 0.3524 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.003 0.0158 0.0199
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0653 0.0772
Brugia malayi Trypsin family protein 0.0101 0.0973 0.1003
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0049 0.0377 0.0475
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0049 0.0377 0.0694
Onchocerca volvulus Neurogenic locus notch homolog 0.0027 0.0126 0.0043
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0157 0.1626 1
Echinococcus multilocularis lysine specific demethylase 6a 0.003 0.0158 0.0291
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0179 0.0143
Echinococcus granulosus transmembrane protease serine 3 0.0101 0.0973 0.1794
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0857 0.9706 0.9706
Mycobacterium ulcerans beta-lactamase 0.0073 0.0653 0.3583
Echinococcus multilocularis JmjC domain containing protein 4 0.003 0.0158 0.0291
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0487 0.5427 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0158 0.0163
Schistosoma mansoni hypothetical protein 0.0101 0.0973 0.0973
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0191 0.0226
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0194 0.2051 0.2113
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0025 0.0103 0.0189
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Plasmodium vivax glutathione reductase, putative 0.0038 0.0251 0.0278
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Trypanosoma brucei hypothetical protein, conserved 0.0704 0.7935 1
Echinococcus multilocularis Mastin 0.0101 0.0973 0.1794
Loa Loa (eye worm) hypothetical protein 0.0097 0.0928 0.0956
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.2471 0.4553
Onchocerca volvulus 0.0757 0.8545 0.8794
Schistosoma mansoni alpha-glucosidase 0.0332 0.3642 0.3642
Echinococcus multilocularis glycogen debranching enzyme 0.0157 0.1618 0.2982
Echinococcus multilocularis neurogenic locus notch protein 0.0027 0.0126 0.0232
Loa Loa (eye worm) hypothetical protein 0.004 0.0275 0.0283
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Brugia malayi Thioredoxin reductase 0.0038 0.0251 0.0258
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0026 0.011 0.5
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.0027 0.0049
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.006 0.0502 0.0594
Echinococcus multilocularis protein jagged 1 0.0027 0.0126 0.0232
Loa Loa (eye worm) jmjC domain-containing protein 0.0113 0.1122 0.1156
Echinococcus multilocularis neurogenic locus notch protein 0.0027 0.0126 0.0232
Trichomonas vaginalis glycogen debranching enzyme, putative 0.0157 0.1618 0.1912
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0653 0.1034
Schistosoma mansoni lipoxygenase 0.0044 0.0322 0.0322
Onchocerca volvulus Arrow homolog 0.0084 0.0779 0.0722
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0064 0.0551 0.1015
Schistosoma mansoni hypothetical protein 0.0047 0.0355 0.0355
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0146 0.0173
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Loa Loa (eye worm) hypothetical protein 0.0035 0.022 0.0226
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0044 0.0322 0.0592
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Loa Loa (eye worm) hypothetical protein 0.0194 0.2051 0.2113
Entamoeba histolytica glycogen debranching enzyme, putative 0.0157 0.1618 0.2982
Echinococcus granulosus GPCR family 2 0.0061 0.0521 0.096
Echinococcus multilocularis lysosomal alpha glucosidase 0.0366 0.4037 0.7439
Trichomonas vaginalis chromobox protein, putative 0.0093 0.0881 0.1041
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0086 0.0806 0.075
Onchocerca volvulus Alhambra homolog 0.0093 0.0882 0.0829
Schistosoma mansoni alpha glucosidase 0.0082 0.0755 0.0755
Trichomonas vaginalis sucrase-isomaltase, putative 0.0082 0.0755 0.0892
Brugia malayi Glycosyl hydrolases family 31 protein 0.0366 0.4037 0.4159
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0026 0.0118 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.015 0.0177
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0071 0.0633 0.0653
Onchocerca volvulus 0.075 0.8463 0.8708
Loa Loa (eye worm) hypothetical protein 0.0159 0.1645 0.1695
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0026 0.0118 0.0218
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Brugia malayi AF-10 protein 0.003 0.0162 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0653 0.0823
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0047 0.036 0.0425
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0101 0.0973 0.1003
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0101 0.0973 0.1794
Echinococcus multilocularis CREB binding protein 0.0057 0.047 0.0865
Loa Loa (eye worm) hypothetical protein 0.0071 0.0633 0.0653
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0092 0.0871 0.0897
Loa Loa (eye worm) hypothetical protein 0.003 0.0158 0.0163
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0487 0.5427 0.6839
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0084 0.0779 0.0802
Echinococcus multilocularis transmembrane protease serine 3 0.0101 0.0973 0.1794
Echinococcus granulosus neutral alpha glucosidase AB 0.0082 0.0755 0.1391
Brugia malayi Bromodomain containing protein 0.0094 0.0898 0.0926
Onchocerca volvulus 0.0027 0.0126 0.0043
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0653 0.107
Schistosoma mansoni cellular tumor antigen P53 0.0035 0.022 0.022
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0251 0.0278
Echinococcus granulosus chromobox protein 1 0.0154 0.1584 0.2919
Schistosoma mansoni hypothetical protein 0.0113 0.1117 0.1117
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0047 0.036 0.0425
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Plasmodium falciparum heterochromatin protein 1 0.0025 0.0103 0.0189
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0037 0.0236 0.0244
Echinococcus granulosus neuropeptide s receptor 0.0381 0.4205 0.7748
Mycobacterium tuberculosis Conserved protein 0.0073 0.0653 0.107
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0121
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0002 0.0003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0037 0.0236 0.0436
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0061 0.0521 0.0537
Trichomonas vaginalis chromobox protein, putative 0.0093 0.0881 0.1041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Schistosoma mansoni survival motor neuron protein 0.0047 0.0355 0.0355
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0908 0.0908
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Onchocerca volvulus 0.0101 0.0973 0.0924
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0087 0.0812 0.1383
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0002 0.0002
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0003
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0653 0.0673
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0653 0.107
Schistosoma mansoni chromobox protein 0.0025 0.0103 0.0103
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0025 0.0103 0.0189
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Schistosoma mansoni laminin gamma-3 chain 0.0027 0.0126 0.0126
Echinococcus multilocularis fibropellin Ia 0.0027 0.0126 0.0232
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0027 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.0755 0.0951
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0136 0.016
Echinococcus multilocularis L aminoadipate semialdehyde 0.0092 0.0871 0.1605
Echinococcus multilocularis dnaJ subfamily B 0.0335 0.3678 0.6778
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Trypanosoma brucei glycosyl hydrolase-like protein 0.0047 0.036 0.0454
Echinococcus granulosus chromobox protein 1 0.0154 0.1584 0.2919
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0126 0.1268 0.2337
Loa Loa (eye worm) hypothetical protein 0.0092 0.0871 0.0897
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0653 0.0823
Echinococcus granulosus L aminoadipate semialdehyde 0.0092 0.0871 0.1605
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0157 0.1626 0.2987
Leishmania major phosphopantetheinyl transferase-like protein 0.0026 0.011 0.0203
Echinococcus granulosus Chromo domain 0.0025 0.0103 0.0189
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0653 0.0772
Echinococcus multilocularis fibrillin 1 0.0071 0.0633 0.1167
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0653 0.1204
Echinococcus multilocularis protein jagged 2 0.0027 0.0126 0.0232
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0092 0.0871 0.0871
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.006 0.0502 0.0594
Onchocerca volvulus 0.0067 0.0591 0.0527
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Schistosoma mansoni jumonji/arid domain-containing protein 0.0113 0.1122 0.1122
Schistosoma mansoni jumonji/arid domain-containing protein 0.0113 0.1122 0.1122
Brugia malayi Delta serrate ligand family protein 0.0027 0.0126 0.013
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0366 0.4037 0.4159
Echinococcus granulosus Mastin 0.0101 0.0973 0.1794
Echinococcus granulosus protein jagged 2 0.0027 0.0126 0.0232
Loa Loa (eye worm) hypothetical protein 0.0096 0.0924 0.0952
Brugia malayi Trypsin family protein 0.0857 0.9706 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0164 0.0194
Echinococcus granulosus neurogenic locus notch protein 0.0027 0.0126 0.0232
Loa Loa (eye worm) beta-lactamase 0.0073 0.0653 0.0673
Schistosoma mansoni hypothetical protein 0.0093 0.0882 0.0882
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0377 0.0388
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0082 0.0755 0.0778
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0025 0.0103 0.0189
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1268 0.7641
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0126
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0103 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0146 0.0173
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892
Echinococcus granulosus protein jagged 1 0.0027 0.0126 0.0232
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0082 0.0755 0.1391
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0025 0.0103 0.0189
Schistosoma mansoni cpg binding protein 0.0025 0.01 0.01
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0064 0.0551 0.0568
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0653 0.0772
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0002 0.0002
Brugia malayi CUB domain containing protein 0.0026 0.0107 0.011
Onchocerca volvulus Putative cubilin 0.004 0.0275 0.0198
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0923 0.1603
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0487 0.5427 0.5591
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0157 0.1626 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Onchocerca volvulus 0.0069 0.0611 0.0548
Echinococcus granulosus enteropeptidase 0.0101 0.0973 0.1794
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0139
Schistosoma mansoni hypothetical protein 0.0069 0.0611 0.0611
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0103 0.0121
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Brugia malayi SET domain containing protein 0.0029 0.0149 0.0153
Echinococcus granulosus PHD finger protein rhinoceros 0.0093 0.0882 0.1625
Brugia malayi Calcium binding EGF domain containing protein 0.0071 0.0633 0.0653
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0236 0.0236
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0082 0.0755 0.1391
Loa Loa (eye worm) Notch2 0.0027 0.0126 0.013
Loa Loa (eye worm) MH2 domain-containing protein 0.0098 0.0941 0.0969
Loa Loa (eye worm) transcription factor SMAD2 0.0098 0.0941 0.0969
Onchocerca volvulus Slit protein homolog 0.0027 0.0126 0.0043
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0487 0.5427 1
Onchocerca volvulus 0.0101 0.0973 0.0924
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Echinococcus multilocularis jumonji domain containing 1A 0.003 0.0158 0.0291
Schistosoma mansoni cpg binding protein 0.0024 0.0084 0.0084
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0026 0.011 0.0203
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Brugia malayi Protein cec-1. 0.0025 0.0103 0.0106
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Loa Loa (eye worm) hypothetical protein 0.0056 0.0453 0.0467
Mycobacterium ulcerans hypothetical protein 0.0101 0.0973 0.5695
Loa Loa (eye worm) hypothetical protein 0.0084 0.0779 0.0802
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0101 0.0973 0.1794
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0251 0.0258
Schistosoma mansoni cpg binding protein 0.0025 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Echinococcus multilocularis neuropeptide s receptor 0.0381 0.4205 0.7748
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0806 0.0952
Brugia malayi Latrophilin receptor protein 2 0.0061 0.0521 0.0537
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0487 0.5427 0.6839
Trichomonas vaginalis maltase-glucoamylase, putative 0.0047 0.036 0.0425
Brugia malayi Amylo-alpha-1,6-glucosidase family protein 0.0157 0.1618 0.1668
Loa Loa (eye worm) hypothetical protein 0.0025 0.0103 0.0106
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Mycobacterium ulcerans hypothetical protein 0.0073 0.0653 0.3583
Echinococcus granulosus Tolloid protein 1 0.0084 0.0782 0.1441
Schistosoma mansoni mixed-lineage leukemia protein mll 0.004 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0032 0.0178 0.0183
Brugia malayi jmjC domain containing protein 0.003 0.0158 0.0163
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0103 0.00000000014506
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Onchocerca volvulus 0.0857 0.9706 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0061 0.0521 0.096
Echinococcus granulosus jumonji domain containing 1A 0.003 0.0158 0.0291
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0487 0.5427 0.5427
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0049 0.0377 0.0475
Echinococcus granulosus voltage gated potassium channel 0.0019 0.0027 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0739 0.0874
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0189
Schistosoma mansoni alpha-glucosidase 0.0332 0.3642 0.3642
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0236 0.0236
Brugia malayi Associated with TFs and helicases family protein 0.0025 0.0103 0.0106
Echinococcus granulosus neurogenic locus notch protein 4 0.0027 0.0126 0.0232
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0162 0.0204
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.0973
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0162 0.0299
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.003 0.0158 0.0158
Onchocerca volvulus 0.0069 0.0611 0.0548
Echinococcus multilocularis neutral alpha glucosidase AB 0.0082 0.0755 0.1391
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0103 0.0121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Brugia malayi notch-like transmembrane receptor 0.0027 0.0126 0.013
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0064 0.0551 0.0568
Brugia malayi CXXC zinc finger family protein 0.0024 0.0084 0.0087
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Brugia malayi Fibulin-1 precursor 0.0071 0.0633 0.0653
Echinococcus multilocularis chromobox protein 2 0.0025 0.0103 0.0189
Schistosoma mansoni chromobox protein 0.0025 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0086 0.0806 0.083
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0027 0.0027
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0049 0.0377 0.0694
Echinococcus multilocularis phd:f box containing protein 0.003 0.0158 0.0291
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0322 0.3524 0.6494
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0103 0.0121
Trypanosoma cruzi Enriched in surface-labeled proteome protein 12 0.0704 0.7935 1
Schistosoma mansoni jumonji domain containing protein 0.003 0.0158 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Echinococcus multilocularis fat cadherin tumor suppressor 0.0027 0.0126 0.0232
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0031 0.0173 0.0319
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0322 0.3524 0.4164
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0032 0.0179 0.0329
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0487 0.5427 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.015 0.0177
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0049 0.0377 0.0694
Brugia malayi beta-lactamase 0.0073 0.0653 0.0673
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0101 0.0973 0.1794
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0087 0.0812 0.1383
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0516 0.0609
Onchocerca volvulus 0.0027 0.0126 0.0043
Onchocerca volvulus 0.0101 0.0973 0.0924
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Loa Loa (eye worm) helicase 0.0025 0.0103 0.0106
Loa Loa (eye worm) CHromoDomain protein family member 0.0026 0.0118 0.0122
Echinococcus multilocularis neurogenic locus protein delta 0.0027 0.0126 0.0232
Loa Loa (eye worm) trypsin family protein 0.0101 0.0973 0.1003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0377 0.0445
Brugia malayi jmjC domain containing protein 0.003 0.0158 0.0163
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.015 0.0177
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0162 0.0204
Echinococcus granulosus cpg binding protein 0.0025 0.01 0.0184
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0047 0.0059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0131 0.0155
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.012 0.1198 0.1198
Echinococcus multilocularis protein jagged 1 0.0027 0.0126 0.0232
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0232 0.0274
Brugia malayi EGF-like domain containing protein 0.0027 0.0126 0.013
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0251 0.0316
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0049 0.0377 0.0475
Onchocerca volvulus 0.0096 0.0924 0.0873
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0487 0.5427 0.6413
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0121
Loa Loa (eye worm) notch protein 0.0027 0.0126 0.013
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0882 0.1625
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0079 0.01
Trichomonas vaginalis alpha-glucosidase, putative 0.0082 0.0755 0.0892
Schistosoma mansoni chromobox protein 0.0154 0.1584 0.1584
Brugia malayi glutathione reductase 0.0038 0.0251 0.0258
Onchocerca volvulus 0.012 0.1198 0.1158
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0031 0.0173 0.0319
Loa Loa (eye worm) glutathione reductase 0.0038 0.0251 0.0258
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Echinococcus multilocularis Tolloid protein 1 0.0084 0.0782 0.1441
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0516 0.0609
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0487 0.5427 1
Onchocerca volvulus 0.0025 0.0103 0.0019
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.013
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0653 0.0653
Brugia malayi jmjC domain containing protein 0.003 0.0158 0.0163
Leishmania major trypanothione reductase 0.0038 0.0251 0.0462
Onchocerca volvulus 0.0101 0.0973 0.0924
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0019 0.0027 0.0027
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0084 0.0782 0.0782
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0251 0.0462
Plasmodium falciparum thioredoxin reductase 0.0038 0.0251 0.0462
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0653 0.0772
Loa Loa (eye worm) hypothetical protein 0.0101 0.0973 0.1003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0164 0.0194
Brugia malayi jmjC domain containing protein 0.003 0.0158 0.0163
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0103 0.0189
Toxoplasma gondii histone lysine demethylase JMJD6a 0.003 0.0158 0.0291
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0303 0.3314 0.6107
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0653 0.107
Trichomonas vaginalis chromobox protein, putative 0.0025 0.0103 0.0121
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0002 0.0002
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0487 0.5427 0.5591
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.1268 0.1268
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0465 0.5183 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0087 0.0812 0.1383
Trichomonas vaginalis chromobox protein, putative 0.0154 0.1584 0.1872
Toxoplasma gondii kringle domain-containing protein 0.0191 0.2014 0.3712
Toxoplasma gondii calcium binding egf domain-containing protein 0.0071 0.0633 0.1167
Schistosoma mansoni voltage-gated potassium channel 0.007 0.0619 0.0619
Leishmania major alpha glucosidase II subunit, putative 0.0082 0.0755 0.1391
Brugia malayi Glycosyl hydrolases family 31 protein 0.0082 0.0755 0.0778
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0487 0.5427 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0653 0.0673
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0002
Echinococcus multilocularis laminin 0.0071 0.0633 0.1167
Schistosoma mansoni notch 0.0027 0.0126 0.0126
Toxoplasma gondii aldehyde dehydrogenase 0.0126 0.1268 0.2337
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0117 0.0139
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1268 0.7641
Onchocerca volvulus 0.0101 0.0973 0.0924
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0101 0.0973 0.0973
Brugia malayi hypothetical protein 0.0101 0.0973 0.1003
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0251 0.0462
Brugia malayi Valyl-tRNA synthetase 0.0025 0.0103 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0261 0.0309
Loa Loa (eye worm) hypothetical protein 0.0061 0.0521 0.0537
Brugia malayi Trypsin family protein 0.0101 0.0973 0.1003
Echinococcus granulosus tumor protein p63 0.0241 0.2594 0.478
Entamoeba histolytica hypothetical protein 0.0025 0.0103 0.0189
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1268 0.7641
Trichomonas vaginalis alpha-glucosidase, putative 0.0047 0.036 0.0425
Plasmodium falciparum phd finger protein, putative 0.0093 0.0882 0.1625
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0049 0.0377 0.0377
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0103 0.0189
Brugia malayi Muscle positioning protein 4 0.0096 0.0924 0.0952
Echinococcus granulosus fibropellin Ia 0.0027 0.0126 0.0232
Brugia malayi Cadherin domain containing protein 0.0027 0.0126 0.013
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0487 0.5427 0.6413
Mycobacterium tuberculosis Conserved protein 0.0073 0.0653 0.107
Onchocerca volvulus 0.0027 0.0126 0.0043
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0653 0.0653
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0377 0.0445
Echinococcus multilocularis lysine specific demethylase 5A 0.0112 0.1107 0.2039
Brugia malayi PHD-finger family protein 0.0093 0.0882 0.0908
Loa Loa (eye worm) hypothetical protein 0.0095 0.0908 0.0936
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0002 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0191 0.2014 0.2539
Schistosoma mansoni chromobox protein 0.0154 0.1584 0.1584
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0653 0.3583
Trypanosoma brucei trypanothione reductase 0.0038 0.0251 0.0316
Onchocerca volvulus 0.0027 0.0126 0.0043
Loa Loa (eye worm) amylo-alpha-1,6-glucosidase 0.0076 0.0692 0.0713
Brugia malayi Calcium binding EGF domain containing protein 0.004 0.0275 0.0283
Schistosoma mansoni CREB-binding protein 2 0.0083 0.0771 0.0771
Schistosoma mansoni cercarial elastase (S01 family) 0.0101 0.0973 0.0973
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0002 0.0002

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.