Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0315 | 0.0168 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0969 | 0.0833 |
Entamoeba histolytica | recQ family helicase, putative | 0.0019 | 0.054 | 0.3191 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0019 | 0.054 | 0.1853 |
Trypanosoma brucei | ISWI complex protein | 0.0017 | 0.0392 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0278 | 0.029 |
Schistosoma mansoni | zinc finger protein | 0.0017 | 0.0392 | 0.0392 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.2209 | 0.2303 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0039 | 0.1692 | 0.2212 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0012 | 0.0149 | 0.0000000012504 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0315 | 0.0315 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0315 | 0.0168 |
Brugia malayi | RNA binding protein | 0.0124 | 0.6555 | 0.6798 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.1692 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.1162 | 0.2789 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.3847 | 0.401 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0019 | 0.054 | 0.0397 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0941 | 0.0981 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0149 | 0.0047 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0076 | 0.3781 | 0.3941 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0392 | 0.0392 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0969 | 0.1011 |
Brugia malayi | Bromodomain containing protein | 0.0042 | 0.1826 | 0.1814 |
Schistosoma mansoni | DNA helicase recq5 | 0.0019 | 0.054 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.1978 | 0.2062 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.2035 | 0.1914 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0039 | 0.1692 | 0.1566 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0015 | 0.0278 | 0.0354 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.1162 | 0.2789 |
Brugia malayi | M-phase phosphoprotein, mpp8 | 0.0012 | 0.0149 | 0.0047 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.054 | 0.081 |
Onchocerca volvulus | 0.0033 | 0.1347 | 0.232 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0555 | 0.1117 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0015 | 0.0278 | 0.0354 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.2035 | 0.1914 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.1332 | 0.1332 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.1692 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0019 | 0.0541 | 0.0397 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0177 | 0.0185 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0015 | 0.0278 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0149 | 0.0156 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.054 | 0.0459 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.145 | 0.145 |
Trichomonas vaginalis | chromobox protein, putative | 0.0076 | 0.3781 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0124 | 0.6555 | 0.6502 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0026 | 0.0946 | 0.0808 |
Plasmodium vivax | hypothetical protein, conserved | 0.0012 | 0.0149 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0015 | 0.0278 | 0.0354 |
Trichomonas vaginalis | chromobox protein, putative | 0.0046 | 0.2058 | 0.5254 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0969 | 0.0833 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0026 | 0.0946 | 0.0808 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0016 | 0.037 | 0.0386 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0969 | 0.0969 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0039 | 0.1692 | 0.4248 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0315 | 0.0315 |
Brugia malayi | Associated with TFs and helicases family protein | 0.0012 | 0.0149 | 0.0047 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0016 | 0.037 | 0.037 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0126 | 0.667 | 0.5 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0039 | 0.1692 | 0.1673 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0315 | 0.0329 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.6555 | 0.6555 |
Onchocerca volvulus | 0.0013 | 0.0188 | 0.0076 | |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0062 | 0.2977 | 0.4464 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0046 | 0.2058 | 0.3696 |
Brugia malayi | TAR-binding protein | 0.0124 | 0.6555 | 0.6798 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0555 | 0.1117 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0315 | 0.0329 |
Onchocerca volvulus | 0.0102 | 0.5312 | 1 | |
Toxoplasma gondii | chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 | 0.0012 | 0.0149 | 0.0224 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0019 | 0.054 | 0.1076 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0015 | 0.0278 | 0.0354 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0012 | 0.0149 | 0.0883 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0066 | 0.3235 | 0.3235 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0019 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0259 | 0.027 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0177 | 0.9593 | 0.9587 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0177 | 0.9593 | 1 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0016 | 0.037 | 0.0224 |
Schistosoma mansoni | lamin | 0.0027 | 0.0969 | 0.0969 |
Onchocerca volvulus | 0.0031 | 0.1229 | 0.2091 | |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0012 | 0.0149 | 0.0149 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.1678 | 0.1552 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0149 | 0.0156 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.2035 | 0.1914 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0315 | 0.0168 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0012 | 0.0149 | 0.0883 |
Schistosoma mansoni | chromobox protein | 0.0012 | 0.0149 | 0.0149 |
Toxoplasma gondii | 'chromo' (CHRromatin Organization MOdifier) domain-containing protein | 0.0012 | 0.0149 | 0.0224 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.1873 | 0.4746 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0019 | 0.054 | 0.0563 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0019 | 0.0555 | 0.1117 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0315 | 0.0315 |
Onchocerca volvulus | 0.0027 | 0.0969 | 0.1589 | |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0149 | 0.0156 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0969 | 0.0833 |
Entamoeba histolytica | hypothetical protein | 0.0012 | 0.0149 | 0.0883 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.2035 | 0.2035 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.1229 | 0.1229 |
Plasmodium vivax | hypothetical protein, conserved | 0.0012 | 0.0149 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0725 | 0.0755 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0019 | 0.054 | 0.0397 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0124 | 0.6555 | 0.6798 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0012 | 0.0149 | 0.0000000012504 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0315 | 0.0315 |
Trypanosoma cruzi | ISWI complex protein | 0.0017 | 0.0392 | 0.0808 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0315 | 0.0168 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0015 | 0.0278 | 0.0354 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0315 | 0.0168 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0019 | 0.054 | 0.0397 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0019 | 0.0555 | 0.1117 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.2209 | 0.2218 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.2209 | 0.2218 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0149 | 0.0156 |
Treponema pallidum | ATP-dependent DNA helicase | 0.001 | 0 | 0.5 |
Schistosoma mansoni | chromobox protein | 0.0076 | 0.3781 | 0.3781 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0012 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0124 | 0.6555 | 0.6832 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.2035 | 0.2035 |
Echinococcus multilocularis | bloom syndrome protein | 0.0019 | 0.054 | 0.0397 |
Schistosoma mansoni | lamin | 0.0027 | 0.0969 | 0.0969 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0969 | 0.0833 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0541 | 0.0564 |
Echinococcus granulosus | Chromo domain | 0.0012 | 0.0149 | 0.000000000461 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0259 | 0.0163 |
Echinococcus multilocularis | tar DNA binding protein | 0.0124 | 0.6555 | 0.6502 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0019 | 0.0541 | 0.0541 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0177 | 0.0028 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0555 | 0.1117 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.0502 | 0.0502 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1873 | 0.1952 |
Trichomonas vaginalis | chromobox protein, putative | 0.0046 | 0.2058 | 0.5254 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0039 | 0.1692 | 0.4248 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0126 | 0.667 | 0.5 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.054 | 0.081 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0067 | 0.3262 | 0.3159 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0019 | 0.054 | 0.0397 |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0.0392 | 0.0179 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0177 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0149 | 0.0156 |
Brugia malayi | SET domain containing protein | 0.0013 | 0.0188 | 0.0089 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0019 | 0.054 | 0.1076 |
Loa Loa (eye worm) | RecQ helicase | 0.0019 | 0.054 | 0.0563 |
Trypanosoma brucei | glucosidase, putative | 0.0039 | 0.1692 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0969 | 0.1011 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.2209 | 0.2303 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0019 | 0.054 | 0.041 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0969 | 0.0912 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0177 | 0.9593 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0016 | 0.0367 | 0.0599 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0019 | 0.0541 | 0.0397 |
Brugia malayi | Heterochromatin protein 1 | 0.0076 | 0.3781 | 0.3875 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0015 | 0.0278 | 0.0354 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0149 | 0.0156 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0019 | 0.054 | 0.1076 |
Schistosoma mansoni | bromodomain containing protein | 0.007 | 0.3485 | 0.3485 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0015 | 0.0278 | 0.0354 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0039 | 0.1692 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0149 | 0.0156 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0725 | 0.0725 |
Echinococcus granulosus | zinc finger protein | 0.0023 | 0.0761 | 0.0621 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.1332 | 0.1294 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 0.054 | 0.0459 |
Plasmodium falciparum | chromodomain-helicase-DNA-binding protein 1 homolog, putative | 0.0012 | 0.0149 | 0.000000011626 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0039 | 0.1692 | 0.4248 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0126 | 0.667 | 0.6619 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0019 | 0.054 | 0.1853 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0149 | 0.0156 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0126 | 0.667 | 0.667 |
Schistosoma mansoni | chromobox protein | 0.0012 | 0.0149 | 0.0149 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0012 | 0.0149 | 0.0000000012504 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0039 | 0.1692 | 0.2537 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.1229 | 0.1281 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0039 | 0.1692 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0035 | 0.145 | 0.132 |
Schistosoma mansoni | alpha glucosidase | 0.0039 | 0.1692 | 0.1692 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0555 | 0.1117 |
Onchocerca volvulus | Uncharacterized family 31 glucosidase KIAA1161 homolog | 0.0015 | 0.0278 | 0.0249 |
Echinococcus granulosus | chromobox protein 1 | 0.0076 | 0.3781 | 0.3687 |
Onchocerca volvulus | 0.0027 | 0.0969 | 0.1589 | |
Trypanosoma cruzi | ISWI complex protein | 0.0017 | 0.0392 | 0.0808 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 1 | 1 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0019 | 0.054 | 0.5 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0019 | 0.0502 | 0.0358 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1347 | 0.1404 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.2035 | 0.2035 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.1678 | 0.1552 |
Echinococcus multilocularis | chromobox protein 1 | 0.0076 | 0.3781 | 0.3687 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0149 | 0.0149 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.145 | 0.145 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.183 | 0.1908 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0039 | 0.1692 | 0.4248 |
Schistosoma mansoni | DNA helicase recq1 | 0.0019 | 0.054 | 0.054 |
Schistosoma mansoni | zinc finger protein | 0.0023 | 0.0761 | 0.0761 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0555 | 0.1117 |
Entamoeba histolytica | hypothetical protein | 0.0012 | 0.0149 | 0.0883 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0969 | 0.0912 |
Brugia malayi | Bromodomain containing protein | 0.0083 | 0.4215 | 0.4332 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.0502 | 0.0502 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0969 | 0.1011 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0016 | 0.0367 | 0.0599 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.054 | 0.0563 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.6555 | 0.6555 |
Brugia malayi | CHD4 protein | 0.0016 | 0.037 | 0.028 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0016 | 0.037 | 0.0224 |
Schistosoma mansoni | alpha-glucosidase | 0.0152 | 0.8179 | 0.8179 |
Entamoeba histolytica | chromodomain-helicase-DNA-binding protein, putative | 0.0012 | 0.0149 | 0.0883 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0177 | 0.9593 | 0.9587 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0026 | 0.0946 | 0.0946 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0019 | 0.054 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0126 | 0.667 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.1229 | 0.1185 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0042 | 0.1873 | 0.3338 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 1 | 0.0012 | 0.0149 | 0.000000000461 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0019 | 0.054 | 0.0459 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.054 | 0.0563 |
Toxoplasma gondii | 'chromo' (CHRromatin Organization MOdifier) domain-containing protein | 0.0012 | 0.0149 | 0.0224 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0126 | 0.667 | 0.667 |
Entamoeba histolytica | hypothetical protein | 0.0012 | 0.0149 | 0.0883 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0039 | 0.1692 | 0.4248 |
Echinococcus multilocularis | cpg binding protein | 0.0035 | 0.145 | 0.132 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0039 | 0.1692 | 0.1764 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0012 | 0.0149 | 0.0149 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0039 | 0.1692 | 0.4248 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0149 | 0.0156 |
Loa Loa (eye worm) | RNA binding protein | 0.0124 | 0.6555 | 0.6832 |
Schistosoma mansoni | chromobox protein | 0.0076 | 0.3781 | 0.3781 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 1 | 0.0012 | 0.0149 | 0.000000000461 |
Brugia malayi | Type III restriction enzyme, res subunit family protein | 0.0012 | 0.0149 | 0.0047 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0019 | 0.0502 | 0.0358 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1332 | 0.1389 |
Plasmodium vivax | heterochromatin protein 1, putative | 0.0012 | 0.0149 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0315 | 0.0222 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0039 | 0.1692 | 0.4248 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0019 | 0.054 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0124 | 0.6555 | 0.6832 |
Echinococcus multilocularis | zinc finger protein | 0.0023 | 0.0761 | 0.0621 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.6555 | 0.6555 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.2035 | 0.2035 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0315 | 0.0222 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0013 | 0.0188 | 0.0188 |
Echinococcus multilocularis | chromobox protein 1 | 0.0076 | 0.3781 | 0.3687 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0969 | 0.0833 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.2199 | 0.2292 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0177 | 0.9593 | 0.9587 |
Brugia malayi | Protein cec-1. | 0.0012 | 0.0149 | 0.0047 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0039 | 0.1692 | 0.4248 |
Echinococcus multilocularis | geminin | 0.0184 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.6555 | 0.6555 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0039 | 0.1692 | 0.1566 |
Schistosoma mansoni | alpha-glucosidase | 0.0152 | 0.8179 | 0.8179 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0126 | 0.667 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0126 | 0.667 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0126 | 0.667 | 0.5 |
Echinococcus granulosus | lamin | 0.0027 | 0.0969 | 0.0833 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.2035 | 0.1914 |
Echinococcus granulosus | chromobox protein 1 | 0.0076 | 0.3781 | 0.3687 |
Echinococcus multilocularis | Chromo domain | 0.0012 | 0.0149 | 0.000000000461 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0016 | 0.0337 | 0.0518 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.2035 | 0.2121 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0039 | 0.1692 | 0.4248 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.1873 | 0.4746 |
Brugia malayi | Valyl-tRNA synthetase | 0.0012 | 0.0149 | 0.0047 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0067 | 0.3262 | 0.3159 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.1093 | 0.1042 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.6555 | 0.6555 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0015 | 0.0278 | 0.0354 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0126 | 0.667 | 0.6619 |
Loa Loa (eye worm) | helicase | 0.0012 | 0.0149 | 0.0156 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0015 | 0.0278 | 0.1642 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0315 | 0.0168 |
Trichomonas vaginalis | chromobox protein, putative | 0.0076 | 0.3781 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0019 | 0.0555 | 0.1117 |
Echinococcus granulosus | bloom syndrome protein | 0.0019 | 0.054 | 0.0397 |
Brugia malayi | chromobox protein homolog 3 | 0.0042 | 0.1873 | 0.1864 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 7.2 % | Cytotoxicity against human MCF7 cells at 0.64 ug/ml after 24 hrs by MTT assay | ChEMBL. | 20451307 |
Activity (functional) | = 13.3 % | Cytotoxicity against human MCF7 cells at 1.6 ug/ml after 24 hrs by MTT assay | ChEMBL. | 20451307 |
Activity (functional) | = 15.5 % | Cytotoxicity against human HT-29 cells at 0.64 ug/ml after 24 hrs by MTT assay | ChEMBL. | 20451307 |
Activity (functional) | = 23.8 % | Cytotoxicity against human MCF7 cells at 6.4 ug/ml after 24 hrs by MTT assay | ChEMBL. | 20451307 |
Activity (functional) | = 26 % | Cytotoxicity against human HT-29 cells at 1.6 ug/ml after 24 hrs by MTT assay | ChEMBL. | 20451307 |
Activity (functional) | = 26.8 % | Cytotoxicity against human HT-29 cells at 6.4 ug/ml after 24 hrs by MTT assay | ChEMBL. | 20451307 |
Activity (functional) | = 28.3 % | Cytotoxicity against human MCF7 cells at 16 ug/ml after 24 hrs by MTT assay | ChEMBL. | 20451307 |
Activity (functional) | = 33.6 % | Cytotoxicity against human MCF7 cells at 32 ug/ml after 24 hrs by MTT assay | ChEMBL. | 20451307 |
Activity (functional) | = 37 % | Cytotoxicity against human HT-29 cells at 16 ug/ml after 24 hrs by MTT assay | ChEMBL. | 20451307 |
Activity (functional) | = 40 % | Cytotoxicity against human HT-29 cells at 32 ug/ml after 24 hrs by MTT assay | ChEMBL. | 20451307 |
Activity (functional) | = 49.5 % | Cytotoxicity against human MCF7 cells at 80 ug/ml after 24 hrs by MTT assay | ChEMBL. | 20451307 |
Activity (functional) | = 54.5 % | Cytotoxicity against human HT-29 cells at 80 ug/ml after 24 hrs by MTT assay | ChEMBL. | 20451307 |
IC50 (functional) | = 65.5 ug ml-1 | Cytotoxicity against human HT-29 cells after 24 hrs by MTT assay | ChEMBL. | 20451307 |
IC50 (functional) | = 80 ug ml-1 | Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay | ChEMBL. | 20451307 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.