Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0147 | 0.0616 | 0.0516 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.0114 | 0.0089 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0091 | 0.0283 | 0.1737 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0073 | 0.0179 | 0.0419 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0195 | 0.09 | 0.0802 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0661 | 0.3652 | 0.3652 |
Leishmania major | methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein | 0.0661 | 0.3652 | 0.3634 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0088 | 0.0267 | 0.0163 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.0306 | 0.0203 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0073 | 0.0179 | 0.0075 |
Echinococcus multilocularis | propionyl coenzyme A carboxylase beta chain | 0.0235 | 0.1136 | 0.1041 |
Trypanosoma brucei | dihydrolipoamide branched chain transacylase, putative | 0.0061 | 0.0106 | 0.0106 |
Echinococcus multilocularis | propionyl coenzyme A carboxylase alpha chain | 0.0661 | 0.3652 | 0.3584 |
Toxoplasma gondii | pyruvate carboxylase | 0.0661 | 0.3652 | 0.3584 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.0114 | 0.0089 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0072 | 0.0173 | 0.0358 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1373 | 0.7861 | 0.7838 |
Mycobacterium leprae | conserved hypothetical protein | 0.0073 | 0.0179 | 0.0419 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0091 | 0.0283 | 0.0643 |
Brugia malayi | dihydrolipoamide S-acetyltransferase precursor, putative | 0.0061 | 0.0106 | 0.0081 |
Mycobacterium ulcerans | carbamoyl phosphate synthase large subunit | 0.0149 | 0.0629 | 0.1659 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 4 AccD4_2 | 0.0235 | 0.1136 | 0.3058 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0114 | 0.0008 |
Onchocerca volvulus | 0.0195 | 0.09 | 0.2265 | |
Trypanosoma brucei | 2-oxoglutarate dehydrogenase E2 component, putative | 0.0061 | 0.0106 | 0.0106 |
Brugia malayi | Muscleblind-like protein | 0.0163 | 0.071 | 0.071 |
Brugia malayi | beta-lactamase family protein | 0.0073 | 0.0179 | 0.0158 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0073 | 0.0179 | 0.0419 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.0114 | 0.0089 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.1707 | 0.9834 | 0.9833 |
Loa Loa (eye worm) | carboxyl transferase domain-containing protein | 0.1674 | 0.9641 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.0306 | 0.0203 |
Brugia malayi | beta-lactamase family protein | 0.0073 | 0.0179 | 0.0158 |
Schistosoma mansoni | pyruvate carboxylase | 0.0661 | 0.3652 | 0.3584 |
Entamoeba histolytica | hypothetical protein | 0.0147 | 0.0616 | 0.4009 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0072 | 0.0173 | 0.0358 |
Trypanosoma cruzi | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0235 | 0.1136 | 0.172 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0179 | 0.0123 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0036 | 0.0001 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0114 | 0.0008 |
Leishmania major | hypothetical protein, conserved | 0.0073 | 0.0179 | 0.0152 |
Loa Loa (eye worm) | beta-lactamase | 0.0073 | 0.0179 | 0.0158 |
Echinococcus granulosus | tumor protein p63 | 0.1333 | 0.7625 | 0.7599 |
Wolbachia endosymbiont of Brugia malayi | Acetyl-CoA carboxylase, carboxyltransferase component | 0.0235 | 0.1136 | 0.2905 |
Onchocerca volvulus | 0.0088 | 0.0267 | 0.0622 | |
Chlamydia trachomatis | biotin carboxylase | 0.06 | 0.3293 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0088 | 0.0267 | 0.0229 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0067 | 0.0145 | 0.0286 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0614 | 0.3376 | 0.3483 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0073 | 0.0179 | 0.0419 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.0067 | 0.0081 |
Mycobacterium leprae | ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 | 0.0235 | 0.1136 | 0.3058 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0397 | 0.2092 | 0.2147 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0067 | 0.0145 | 0.0286 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.0761 | 0.0662 |
Echinococcus granulosus | propionyl coenzyme A carboxylase beta chain | 0.0235 | 0.1136 | 0.1041 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.0661 | 0.3652 | 0.5922 |
Schistosoma mansoni | hypothetical protein | 0.0126 | 0.0489 | 0.0387 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0067 | 0.0145 | 0.0286 |
Echinococcus granulosus | geminin | 0.0172 | 0.0761 | 0.0662 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1373 | 0.7861 | 0.7838 |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.1735 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0172 | 0.0761 | 0.0662 |
Wolbachia endosymbiont of Brugia malayi | Acetyl/propionyl-CoA carboxylase, alpha subunit | 0.0661 | 0.3652 | 1 |
Echinococcus granulosus | microtubule associated protein 2 | 0.1373 | 0.7861 | 0.7838 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.0067 | 0.0081 |
Echinococcus multilocularis | tumor protein p63 | 0.1333 | 0.7625 | 0.7599 |
Schistosoma mansoni | hypothetical protein | 0.0126 | 0.0489 | 0.0387 |
Schistosoma mansoni | propionyl-CoA carboxylase beta chain mitochondrial precursor | 0.0235 | 0.1136 | 0.1041 |
Plasmodium falciparum | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.1255 | 0.7167 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0073 | 0.0179 | 0.0105 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0126 | 0.0489 | 0.0387 |
Entamoeba histolytica | acetyl-coA carboxylase, putative | 0.0296 | 0.1495 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0614 | 0.3376 | 0.3483 |
Leishmania major | acetyl-CoA carboxylase, putative | 0.1735 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0036 | 0.0001 |
Leishmania major | dihydrolipoamide branched chain transacylase, putative | 0.0061 | 0.0106 | 0.0078 |
Plasmodium vivax | carbamoyl phosphate synthetase, putative | 0.0149 | 0.0629 | 0.0742 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.071 | 0.071 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0147 | 0.0616 | 0.0516 |
Trypanosoma cruzi | glutamine dependent carbamoyl-phosphate synthase, putative | 0.0149 | 0.0629 | 0.0874 |
Plasmodium falciparum | carbamoyl phosphate synthetase | 0.0149 | 0.0629 | 0.0742 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0091 | 0.0283 | 0.0256 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0106 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.09 | 0.0907 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0088 | 0.0267 | 0.0163 |
Mycobacterium tuberculosis | Probable branched-chain keto acid dehydrogenase E2 component BkdC | 0.0061 | 0.0106 | 0.0215 |
Trypanosoma cruzi | acetyl-CoA carboxylase | 0.1074 | 0.6094 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.0114 | 0.0008 |
Trichomonas vaginalis | set domain proteins, putative | 0.0699 | 0.3877 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0061 | 0.0106 | 0.0215 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0059 | 0.0095 | 0.0154 |
Trypanosoma brucei | unspecified product | 0.0434 | 0.2314 | 0.2314 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0179 | 0.0375 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0114 | 0.0008 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0091 | 0.0283 | 0.0179 |
Echinococcus granulosus | muscleblind protein | 0.0163 | 0.071 | 0.0611 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.0114 | 0.0008 |
Trypanosoma brucei | pyruvate dehydrogenase complex E3 binding protein, putative | 0.0061 | 0.0106 | 0.0106 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0095 | 0.0306 | 0.029 |
Leishmania major | hypothetical protein, conserved | 0.0076 | 0.0196 | 0.0169 |
Entamoeba histolytica | hypothetical protein | 0.0147 | 0.0616 | 0.4009 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.0306 | 0.0203 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0077 | 0.0204 | 0.0439 |
Trypanosoma brucei | dihydrolipoamide acetyltransferase E2 subunit, putative | 0.0061 | 0.0106 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0271 | 0.135 | 0.1375 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0121 | 0.0463 | 0.0453 |
Brugia malayi | Carboxyl transferase domain containing protein | 0.1674 | 0.9641 | 1 |
Leishmania major | carboxylase, putative | 0.0661 | 0.3652 | 0.3634 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0073 | 0.0179 | 0.0419 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0091 | 0.0283 | 0.0256 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0036 | 0.0001 |
Mycobacterium ulcerans | hypothetical protein | 0.0073 | 0.0179 | 0.0419 |
Brugia malayi | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta | 0.0061 | 0.0106 | 0.0081 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0088 | 0.0267 | 0.0163 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0126 | 0.0489 | 0.0387 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0091 | 0.0283 | 0.0265 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.0661 | 0.3652 | 0.5922 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0073 | 0.0179 | 0.0419 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0037 | 0.0009 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0088 | 0.0267 | 0.0163 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.0306 | 0.0203 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.0114 | 0.0089 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0126 | 0.0489 | 0.0387 |
Mycobacterium tuberculosis | Probable pyruvate carboxylase Pca (pyruvic carboxylase) | 0.0661 | 0.3652 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0468 | 0.2513 | 0.6858 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0106 | 0.0081 |
Trypanosoma cruzi | glutamine-dependent carbamoyl-phosphate synthetase, putative | 0.0149 | 0.0629 | 0.0874 |
Trypanosoma cruzi | acetyl-CoA carboxylase, putative | 0.0235 | 0.1136 | 0.172 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 4 AccD4 | 0.0235 | 0.1136 | 0.3058 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0076 | 0.0196 | 0.0151 |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.1735 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0179 | 0.0158 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0073 | 0.0179 | 0.0179 |
Loa Loa (eye worm) | hypothetical protein | 0.0456 | 0.2443 | 0.2513 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0126 | 0.0489 | 0.0479 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0196 | 0.0175 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0073 | 0.0179 | 0.0158 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0147 | 0.0616 | 0.0516 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.0761 | 0.0662 |
Leishmania major | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0235 | 0.1136 | 0.1111 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.0064 | 0.0073 |
Mycobacterium ulcerans | beta-lactamase | 0.0073 | 0.0179 | 0.0419 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0179 | 0.0158 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0073 | 0.0179 | 0.0375 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0179 | 0.0419 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0088 | 0.0267 | 0.0163 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0073 | 0.0179 | 0.0419 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0126 | 0.0489 | 0.0387 |
Mycobacterium leprae | Probable biotinylated protein homolog TB7.3 | 0.0061 | 0.0106 | 0.0215 |
Schistosoma mansoni | hypothetical protein | 0.0126 | 0.0489 | 0.0387 |
Onchocerca volvulus | 0.0073 | 0.0179 | 0.0394 | |
Brugia malayi | RNA binding protein | 0.0062 | 0.0114 | 0.0089 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0091 | 0.0283 | 0.1737 |
Brugia malayi | Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial precursor | 0.0061 | 0.0106 | 0.0081 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0091 | 0.0283 | 0.0179 |
Mycobacterium ulcerans | acetyl/propionyl CoA carboxylase subunit beta | 0.0235 | 0.1136 | 0.3058 |
Entamoeba histolytica | hypothetical protein | 0.0147 | 0.0616 | 0.4009 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0661 | 0.3653 | 0.3585 |
Mycobacterium leprae | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex SucB | 0.0061 | 0.0106 | 0.0215 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0179 | 0.0419 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0114 | 0.0008 |
Mycobacterium leprae | Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) | 0.0235 | 0.1136 | 0.3058 |
Mycobacterium tuberculosis | Biotinylated protein TB7.3 | 0.0061 | 0.0106 | 0.0215 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0067 | 0.0145 | 0.004 |
Mycobacterium tuberculosis | Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 | 0.0235 | 0.1136 | 0.3058 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0267 | 0.0249 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0076 | 0.0196 | 0.0128 |
Toxoplasma gondii | ABC1 family protein | 0.0073 | 0.0179 | 0.0075 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.1735 | 1 | 1 |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.1735 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.0489 | 0.0479 |
Brugia malayi | hypothetical protein | 0.0147 | 0.0616 | 0.0612 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0179 | 0.0419 |
Schistosoma mansoni | aspartate carbamoyltransferase | 0.0149 | 0.0629 | 0.0529 |
Mycobacterium tuberculosis | DlaT, dihydrolipoamide acyltransferase, E2 component of pyruvate dehydrogenase | 0.0061 | 0.0106 | 0.0215 |
Leishmania major | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase, putative | 0.0061 | 0.0106 | 0.0078 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0088 | 0.0267 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0179 | 0.0158 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0397 | 0.2092 | 0.2147 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0106 | 0.0081 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0072 | 0.0173 | 0.0113 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0088 | 0.0267 | 0.0163 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0072 | 0.0173 | 0.0146 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0121 | 0.0463 | 0.0453 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0091 | 0.0283 | 0.0296 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0163 | 0.071 | 0.0611 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 | 0.0661 | 0.3652 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0072 | 0.0173 | 0.0358 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0091 | 0.0283 | 0.0179 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0076 | 0.0196 | 0.0151 |
Trypanosoma brucei | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0235 | 0.1136 | 0.1136 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0073 | 0.0179 | 0.0158 |
Onchocerca volvulus | 0.0699 | 0.3877 | 1 | |
Mycobacterium ulcerans | acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 | 0.0235 | 0.1136 | 0.3058 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 5 AccD5 | 0.0235 | 0.1136 | 0.3058 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0076 | 0.0196 | 0.0196 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 | 0.0661 | 0.3652 | 1 |
Mycobacterium leprae | Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) | 0.0235 | 0.1136 | 0.3058 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0091 | 0.0283 | 0.0296 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0126 | 0.0489 | 0.0479 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0126 | 0.0489 | 0.0479 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0073 | 0.0179 | 0.0419 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0091 | 0.0283 | 0.0643 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0067 | 0.0145 | 0.0286 |
Giardia lamblia | Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative | 0.0296 | 0.1495 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0088 | 0.0267 | 0.0163 |
Leishmania major | dihydrolipoamide acetyltransferase precursor, putative | 0.0061 | 0.0106 | 0.0078 |
Leishmania major | dihydrolipoamide acetyltransferase precursorlike protein | 0.0061 | 0.0106 | 0.0078 |
Mycobacterium tuberculosis | Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie | 0.0661 | 0.3652 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0271 | 0.135 | 0.1257 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0061 | 0.0106 | 0.0184 |
Mycobacterium ulcerans | dihydrolipoamide acetyltransferase | 0.0061 | 0.0106 | 0.0215 |
Schistosoma mansoni | hypothetical protein | 0.0126 | 0.0489 | 0.0387 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0067 | 0.0145 | 0.0286 |
Toxoplasma gondii | carbamoylphosphate synthetase | 0.0149 | 0.0629 | 0.0529 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0073 | 0.0179 | 0.0075 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0076 | 0.0196 | 0.0128 |
Trypanosoma brucei | glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative | 0.0149 | 0.0629 | 0.0629 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0091 | 0.0283 | 0.0283 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0179 | 0.0375 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.0306 | 0.0203 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0067 | 0.0145 | 0.0286 |
Brugia malayi | hypothetical protein | 0.0456 | 0.2443 | 0.2513 |
Echinococcus granulosus | propionyl coenzyme A carboxylase alpha chain | 0.0661 | 0.3652 | 0.3584 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0091 | 0.0283 | 0.0643 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0179 | 0.0158 |
Brugia malayi | MH2 domain containing protein | 0.0121 | 0.0463 | 0.0453 |
Trypanosoma cruzi | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0235 | 0.1136 | 0.172 |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.1735 | 1 | 1 |
Leishmania major | propionyl-coa carboxylase beta chain, putative | 0.0235 | 0.1136 | 0.1111 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0076 | 0.0196 | 0.0128 |
Mycobacterium tuberculosis | Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) | 0.0235 | 0.1136 | 0.3058 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0271 | 0.135 | 0.1375 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0114 | 0.0008 |
Onchocerca volvulus | 0.0073 | 0.0179 | 0.0394 | |
Wolbachia endosymbiont of Brugia malayi | carbamoyl phosphate synthase large subunit | 0.0149 | 0.0629 | 0.1476 |
Onchocerca volvulus | 0.0073 | 0.0179 | 0.0394 | |
Mycobacterium leprae | Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) | 0.0661 | 0.3652 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0616 | 0.0516 |
Echinococcus multilocularis | muscleblind protein | 0.0163 | 0.071 | 0.0611 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0179 | 0.0375 |
Echinococcus multilocularis | GPCR, family 2 | 0.0126 | 0.0489 | 0.0387 |
Brugia malayi | Pre-SET motif family protein | 0.0088 | 0.0267 | 0.0249 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0073 | 0.0179 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0196 | 0.0175 |
Mycobacterium leprae | Probable lipase LipE | 0.0073 | 0.0179 | 0.0419 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0036 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0179 | 0.0158 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0091 | 0.0283 | 0.0265 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0661 | 0.3653 | 0.3585 |
Trichomonas vaginalis | esterase, putative | 0.0073 | 0.0179 | 0.0375 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0073 | 0.0179 | 0.0375 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0661 | 0.3652 | 0.3652 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0072 | 0.0173 | 0.0358 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0091 | 0.0283 | 0.0283 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0085 | 0.0248 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0397 | 0.2092 | 0.2147 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.0114 | 0.0089 |
Echinococcus granulosus | GPCR family 2 | 0.0126 | 0.0489 | 0.0387 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.0306 | 0.0203 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0095 | 0.0306 | 0.029 |
Brugia malayi | beta-lactamase | 0.0073 | 0.0179 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.071 | 0.071 |
Toxoplasma gondii | acyl-CoA carboxyltransferase beta chain, putative | 0.0235 | 0.1136 | 0.1041 |
Mycobacterium ulcerans | lipase LipD | 0.0073 | 0.0179 | 0.0419 |
Plasmodium vivax | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.1255 | 0.7167 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0073 | 0.0179 | 0.0419 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0067 | 0.0145 | 0.0286 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.0067 | 0.0081 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0072 | 0.0173 | 0.0358 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0073 | 0.0179 | 0.0419 |
Schistosoma mansoni | carbamoyl-phosphate synthetase | 0.0149 | 0.0629 | 0.0529 |
Mycobacterium ulcerans | pyruvate carboxylase | 0.0661 | 0.3652 | 1 |
Chlamydia trachomatis | acetyl-coenzyme A carboxylase carboxyl transferase subunit beta | 0.0235 | 0.1136 | 0.3233 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0397 | 0.2092 | 0.2147 |
Leishmania major | carbamoyl-phosphate synthase, putative | 0.0149 | 0.0629 | 0.0603 |
Onchocerca volvulus | 0.0456 | 0.2443 | 0.6275 | |
Treponema pallidum | pyruvate carboxylase subunit B | 0.0061 | 0.0106 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.0064 | 0.0073 |
Mycobacterium ulcerans | bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 | 0.0661 | 0.3652 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.0306 | 0.0203 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0073 | 0.0179 | 0.0075 |
Schistosoma mansoni | carbamoyl-phosphate synthetase | 0.0149 | 0.0629 | 0.0529 |
Mycobacterium ulcerans | acetyl-/propionyl-CoA carboxylase subunit beta | 0.0235 | 0.1136 | 0.3058 |
Entamoeba histolytica | hypothetical protein | 0.0147 | 0.0616 | 0.4009 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0076 | 0.0196 | 0.0092 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0072 | 0.0173 | 0.0173 |
Mycobacterium ulcerans | branched-chain alpha-keto acid dehydrogenase subunit E2 | 0.0061 | 0.0106 | 0.0215 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0179 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0179 | 0.0158 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | Antimicrobial activity against Escherichia coli at 50 ug/disk by disk diffusion assay | ChEMBL. | 18803421 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.