Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0092 | 0.0853 | 0.0853 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0105 | 0.1035 | 0.1035 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0853 | 0.1347 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0073 | 0.059 | 0.0932 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0092 | 0.0853 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.0248 | 0.0248 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0263 | 0.0415 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0686 | 0.9167 | 1 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0068 | 0.0524 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0422 | 0.046 |
Onchocerca volvulus | 0.0483 | 0.6334 | 1 | |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0092 | 0.0853 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0248 | 0.0248 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0092 | 0.0853 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0686 | 0.9167 | 0.9167 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0152 | 0.1697 | 0.1697 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0055 | 0.0336 | 0.0531 |
Loa Loa (eye worm) | RNA binding protein | 0.0463 | 0.6046 | 0.6046 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0048 | 0.0248 | 0.0248 |
Echinococcus granulosus | GPCR family 2 | 0.0048 | 0.0248 | 0.0248 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0149 | 0.1661 | 0.1812 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0073 | 0.059 | 0.0932 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0092 | 0.0853 | 1 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0092 | 0.0853 | 0.0853 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0059 | 0.0391 | 0.0391 |
Schistosoma mansoni | tar DNA-binding protein | 0.0463 | 0.6046 | 0.6595 |
Plasmodium vivax | SET domain protein, putative | 0.0061 | 0.0422 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0068 | 0.0524 | 0.0827 |
Echinococcus granulosus | tar DNA binding protein | 0.0463 | 0.6046 | 0.6046 |
Schistosoma mansoni | survival motor neuron protein | 0.0152 | 0.1697 | 0.1851 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0422 | 0.046 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0463 | 0.6046 | 0.6046 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0073 | 0.0591 | 0.6934 |
Schistosoma mansoni | tar DNA-binding protein | 0.0463 | 0.6046 | 0.6595 |
Onchocerca volvulus | 0.0152 | 0.1697 | 0.2157 | |
Schistosoma mansoni | hypothetical protein | 0.0105 | 0.1035 | 0.1129 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0073 | 0.059 | 0.0932 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.0329 | 0.0519 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0092 | 0.0853 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0073 | 0.059 | 0.0932 |
Entamoeba histolytica | hypothetical protein | 0.0149 | 0.1661 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0425 | 0.5513 | 0.5513 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0061 | 0.0422 | 0.046 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0073 | 0.059 | 0.0932 |
Entamoeba histolytica | hypothetical protein | 0.0149 | 0.1661 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.006 | 0.0403 | 0.0636 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0262 | 0.0413 |
Schistosoma mansoni | hypothetical protein | 0.0152 | 0.1697 | 0.1851 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0068 | 0.0524 | 0.0827 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0068 | 0.0524 | 0.0827 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0853 | 0.1347 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0153 | 0.1713 | 0.1713 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0092 | 0.0853 | 0.093 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0092 | 0.0853 | 0.0853 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0262 | 0.0413 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0853 | 0.1347 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0061 | 0.0422 | 0.0422 |
Entamoeba histolytica | hypothetical protein | 0.0149 | 0.1661 | 1 |
Brugia malayi | RNA binding protein | 0.0463 | 0.6046 | 0.6046 |
Schistosoma mansoni | hypothetical protein | 0.0149 | 0.1661 | 0.1812 |
Brugia malayi | TAR-binding protein | 0.0463 | 0.6046 | 0.6046 |
Trichomonas vaginalis | set domain proteins, putative | 0.0483 | 0.6334 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0463 | 0.6046 | 0.6046 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0463 | 0.6046 | 0.6046 |
Loa Loa (eye worm) | TAR-binding protein | 0.0463 | 0.6046 | 0.6046 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0078 | 0.0665 | 0.105 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0248 | 0.027 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0061 | 0.043 | 0.068 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0263 | 0.0415 |
Entamoeba histolytica | hypothetical protein | 0.0149 | 0.1661 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0425 | 0.5513 | 0.5513 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0048 | 0.0248 | 0.0248 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.0248 | 0.0248 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0055 | 0.0336 | 0.0531 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0068 | 0.0524 | 0.0827 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0422 | 0.0422 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.0248 | 0.0248 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0092 | 0.0853 | 0.0853 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0073 | 0.0591 | 0.6934 |
Schistosoma mansoni | tar DNA-binding protein | 0.0463 | 0.6046 | 0.6595 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0092 | 0.0853 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0263 | 0.0415 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0149 | 0.1661 | 0.1661 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0038 | 0.0103 | 0.1204 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.0329 | 0.0519 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0248 | 0.027 |
Brugia malayi | Pre-SET motif family protein | 0.0061 | 0.0422 | 0.0422 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0686 | 0.9167 | 0.9167 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0061 | 0.0422 | 0.0422 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0061 | 0.0422 | 0.0422 |
Brugia malayi | hypothetical protein | 0.0149 | 0.1661 | 0.1661 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1035 | 0.1035 |
Giardia lamblia | GTOR | 0.0092 | 0.0853 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0153 | 0.1713 | 0.1713 |
Schistosoma mansoni | tar DNA-binding protein | 0.0463 | 0.6046 | 0.6595 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.1713 | 0.1713 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0068 | 0.0524 | 0.0827 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0073 | 0.0591 | 0.6934 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0043 | 0.0177 | 0.207 |
Schistosoma mansoni | tar DNA-binding protein | 0.0463 | 0.6046 | 0.6595 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0068 | 0.0524 | 0.0827 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0248 | 0.027 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0422 | 0.046 |
Echinococcus multilocularis | GPCR, family 2 | 0.0048 | 0.0248 | 0.0248 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0263 | 0.0415 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0262 | 0.0413 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0248 | 0.027 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0055 | 0.0336 | 0.0531 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0048 | 0.0248 | 0.0248 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0068 | 0.0524 | 0.0827 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.0248 | 0.0248 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0153 | 0.1713 | 0.1713 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0149 | 0.1661 | 0.1661 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.