Detailed information for compound 1177182

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 3977.56 | Formula: C177H299N49O54
  • H donors: 56 H acceptors: 54 LogP: -18.4 Rotable bonds: 177
    Rule of 5 violations (Lipinski): 4
  • SMILES: NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)C)CCCCN)CC(C)C)C)C)CC(C)C)CCCCN)C)CCCCN)CC(C)C)C)C)CC(C)C)NC(=O)CNC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)C)CCC(=O)O)CC(C)C)C)C)CC(C)C)CCC(=O)O)C)CCC(=O)O)CC(C)C)C)C)CC(C)C)CCC(=O)O)CO)CCC(=O)N)CC(=O)O)CC(=O)N)C)CCCNC(=N)N)CO)CC(C)C
  • InChi: 1S/C177H299N49O54/c1-82(2)65-117(163(266)197-92(20)141(244)191-96(24)148(251)214-121(69-86(9)10)168(271)209-108(46-35-39-61-179)154(257)195-100(28)145(248)206-110(48-37-41-63-181)158(261)219-118(66-83(3)4)164(267)198-93(21)142(245)192-97(25)149(252)215-122(70-87(11)12)169(272)210-109(47-36-40-62-180)155(258)202-103(31)176(279)280)218-157(260)107(45-34-38-60-178)203-133(231)78-190-153(256)126(74-104-77-188-106-44-33-32-43-105(104)106)223-172(275)125(73-90(17)18)222-175(278)130(81-228)226-159(262)111(49-42-64-187-177(185)186)207-146(249)102(30)201-167(270)127(75-132(184)230)224-173(276)128(76-139(241)242)225-160(263)113(50-55-131(183)229)213-174(277)129(80-227)204-134(232)79-189-152(255)112(51-56-135(233)234)211-170(273)123(71-88(13)14)216-150(253)98(26)193-144(247)95(23)200-166(269)120(68-85(7)8)221-162(265)116(54-59-138(239)240)208-147(250)101(29)196-156(259)114(52-57-136(235)236)212-171(274)124(72-89(15)16)217-151(254)99(27)194-143(246)94(22)199-165(268)119(67-84(5)6)220-161(264)115(53-58-137(237)238)205-140(243)91(19)182/h32-33,43-44,77,82-103,107-130,188,227-228H,34-42,45-76,78-81,178-182H2,1-31H3,(H2,183,229)(H2,184,230)(H,189,255)(H,190,256)(H,191,244)(H,192,245)(H,193,247)(H,194,246)(H,195,257)(H,196,259)(H,197,266)(H,198,267)(H,199,268)(H,200,269)(H,201,270)(H,202,258)(H,203,231)(H,204,232)(H,205,243)(H,206,248)(H,207,249)(H,208,250)(H,209,271)(H,210,272)(H,211,273)(H,212,274)(H,213,277)(H,214,251)(H,215,252)(H,216,253)(H,217,254)(H,218,260)(H,219,261)(H,220,264)(H,221,265)(H,222,278)(H,223,275)(H,224,276)(H,225,263)(H,226,262)(H,233,234)(H,235,236)(H,237,238)(H,239,240)(H,241,242)(H,279,280)(H4,185,186,187)/t91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-/m0/s1
  • InChiKey: VFPYULRHUSSEJK-OQNUDYLKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0222 0.2533 0.4183
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0041 0.0308 0.0657
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0308 0.0296
Brugia malayi Cathepsin L-like precursor 0.0222 0.2533 0.4361
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0276 0.0241
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0114 0.121 0.4445
Loa Loa (eye worm) hypothetical protein 0.0148 0.1631 0.2808
Entamoeba histolytica cysteine protease, putative 0.0114 0.121 0.4138
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0568 0.115
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0222 0.2533 1
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0411 0.0565
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0733 0.1038
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0275 0.3196 0.7087
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0041 0.0308 0.0657
Entamoeba histolytica hypothetical protein 0.0041 0.0308 0.014
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0041 0.0308 0.0296
Loa Loa (eye worm) hypothetical protein 0.0041 0.0308 0.053
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0041 0.0308 0.0657
Brugia malayi cathepsin L-like cysteine proteinase 0.0041 0.0308 0.053
Plasmodium falciparum serine repeat antigen 1 0.0041 0.0308 0.0657
Plasmodium falciparum serine repeat antigen 9 0.0041 0.0308 0.0657
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0041 0.0308 0.0657
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.121 0.1872
Onchocerca volvulus 0.0222 0.2533 0.4152
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0079 0.0777 0.1338
Onchocerca volvulus 0.0492 0.5862 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.2533 0.4183
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0041 0.0308 0.0657
Brugia malayi Cathepsin L-like precursor 0.0148 0.1631 0.2808
Entamoeba histolytica cysteine protease, putative 0.0114 0.121 0.4138
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0275 0.3196 0.7087
Loa Loa (eye worm) hypothetical protein 0.0073 0.0706 0.1216
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0222 0.2533 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.025 0.2879 0.4958
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0041 0.0308 0.053
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0041 0.0308 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.2533 0.4183
Schistosoma mansoni cathepsin C 0.0041 0.0308 0.04
Echinococcus granulosus chromobox protein 1 0.0068 0.0646 0.1116
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0646 0.0887
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0041 0.0308 0.0296
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0222 0.2533 0.4183
Schistosoma mansoni ap endonuclease 0.0057 0.0503 0.0963
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0222 0.2533 0.4361
Mycobacterium tuberculosis Probable esterase LipL 0.0075 0.0733 0.0439
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0411 0.0707
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0225 0.0309
Loa Loa (eye worm) hypothetical protein 0.0041 0.0308 0.053
Echinococcus granulosus survival motor neuron protein 1 0.0241 0.2778 0.6108
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0041 0.0308 0.053
Loa Loa (eye worm) hypothetical protein 0.0056 0.0495 0.0852
Echinococcus granulosus cathepsin L cysteine protease 0.0114 0.121 0.2436
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0568 0.1749
Echinococcus multilocularis GPCR, family 2 0.0079 0.0777 0.0618
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0503 0.1005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0041 0.0308 0.0296
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0129 0.1396 0.1247
Mycobacterium tuberculosis Probable hydrolase 0.0075 0.0733 0.0439
Loa Loa (eye worm) hypothetical protein 0.0075 0.0733 0.1261
Plasmodium vivax serine-repeat antigen (SERA) 0.0041 0.0308 0.0657
Brugia malayi hypothetical protein 0.0028 0.0151 0.0261
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0114 0.121 0.4445
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0041 0.0308 0.0657
Toxoplasma gondii cathepsin B 0.0041 0.0308 0.0657
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.054 0.0867
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0483 0.0905
Echinococcus granulosus tumor protein p63 0.0376 0.4439 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0222 0.2533 0.5534
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0503 0.0339
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0129 0.1396 0.5225
Schistosoma mansoni aldehyde dehydrogenase 0.0129 0.1396 0.3541
Onchocerca volvulus 0.0073 0.0706 0.0942
Entamoeba histolytica cysteine protease, putative 0.0114 0.121 0.4138
Brugia malayi Cathepsin L-like precursor 0.0148 0.1631 0.2808
Schistosoma mansoni cathepsin B (C01 family) 0.0041 0.0308 0.04
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0041 0.0308 0.04
Plasmodium vivax SET domain protein, putative 0.0062 0.0568 0.1749
Trypanosoma cruzi cysteine proteinase, putative 0.0114 0.121 0.4445
Loa Loa (eye worm) hypothetical protein 0.0073 0.0706 0.1216
Loa Loa (eye worm) hypothetical protein 0.0075 0.0733 0.1261
Brugia malayi cathepsin F-like cysteine proteinase 0.0041 0.0308 0.053
Schistosoma mansoni hypothetical protein 0.0079 0.0777 0.1755
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0222 0.2533 1
Trypanosoma cruzi cysteine peptidase, putative 0.0222 0.2533 1
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0411 0.0697
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0041 0.0308 0.0657
Plasmodium vivax vivapain-2 0.0222 0.2533 1
Loa Loa (eye worm) fibroinase 0.0222 0.2533 0.4361
Brugia malayi Latrophilin receptor protein 2 0.0079 0.0777 0.1338
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0222 0.2533 0.4183
Schistosoma mansoni hypothetical protein 0.0311 0.3632 1
Plasmodium vivax hypothetical protein, conserved 0.0075 0.0733 0.2441
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0041 0.0308 0.0296
Mycobacterium tuberculosis Conserved protein 0.0075 0.0733 0.0439
Echinococcus granulosus geminin 0.0166 0.1852 0.394
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0041 0.0308 0.04
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0041 0.0308 0.0657
Onchocerca volvulus Cathepsin F homolog 0.0222 0.2533 0.4152
Loa Loa (eye worm) hypothetical protein 0.0029 0.0163 0.028
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0073 0.0706 0.1216
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0222 0.2533 0.4361
Entamoeba histolytica cysteine proteinase, putative 0.0114 0.121 0.4138
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0041 0.0308 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.2533 0.4183
Loa Loa (eye worm) hypothetical protein 0.0028 0.0151 0.0261
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0041 0.0308 0.0296
Onchocerca volvulus 0.0148 0.1631 0.2567
Echinococcus multilocularis cysteine protease 0.0222 0.2533 0.2404
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0079 0.0777 0.0618
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0503 0.0637
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0206 0.2335 0.2203
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.2533 0.4183
Onchocerca volvulus Cathepsin L homolog 0.0041 0.0308 0.0243
Brugia malayi Papain family cysteine protease containing protein 0.0114 0.121 0.2083
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0041 0.0308 0.04
Mycobacterium leprae Probable lipase LipE 0.0075 0.0733 0.5
Schistosoma mansoni hypothetical protein 0.0049 0.0411 0.0697
Echinococcus granulosus cathepsin l1 0.0222 0.2533 0.5534
Leishmania major cathepsin L-like protease 0.0222 0.2533 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0041 0.0308 0.04
Echinococcus multilocularis beta LACTamase domain containing family member 0.0075 0.0733 0.0573
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0041 0.0308 0.0296
Brugia malayi TAR-binding protein 0.0128 0.1381 0.2378
Mycobacterium tuberculosis Probable lipase LipE 0.0075 0.0733 0.0439
Brugia malayi beta-lactamase family protein 0.0075 0.0733 0.1261
Loa Loa (eye worm) MBCTL1 0.0056 0.0495 0.0852
Loa Loa (eye worm) hypothetical protein 0.0075 0.0733 0.1261
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.2533 0.4183
Entamoeba histolytica cysteine proteinase, putative 0.0114 0.121 0.4138
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0411 0.0424
Plasmodium vivax unspecified product 0.0114 0.121 0.4445
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0503 0.5
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0222 0.2533 1
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0733 0.1038
Onchocerca volvulus 0.0049 0.0411 0.0424
Toxoplasma gondii preprocathepsin c precursor, putative 0.0041 0.0308 0.0657
Echinococcus multilocularis survival motor neuron protein 1 0.0241 0.2778 0.2653
Trypanosoma cruzi cysteine proteinase, putative 0.0114 0.121 0.4445
Onchocerca volvulus 0.0222 0.2533 0.4152
Mycobacterium ulcerans beta-lactamase 0.0075 0.0733 0.2572
Schistosoma mansoni survival motor neuron protein 0.0049 0.0411 0.0697
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0041 0.0308 0.04
Toxoplasma gondii cathepsin CPL 0.0222 0.2533 1
Brugia malayi hypothetical protein 0.0103 0.1072 0.1846
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0129 0.1396 0.1706
Brugia malayi mbt repeat family protein 0.0049 0.0411 0.0707
Loa Loa (eye worm) hypothetical protein 0.0062 0.0568 0.0978
Toxoplasma gondii ABC1 family protein 0.0075 0.0733 0.2441
Schistosoma mansoni tar DNA-binding protein 0.0128 0.1381 0.3499
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0075 0.0733 0.0439
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0275 0.3196 0.5502
Echinococcus granulosus cathepsin L 0.0041 0.0308 0.0324
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0222 0.2533 0.4183
Mycobacterium ulcerans lipase LipD 0.0075 0.0733 0.2572
Echinococcus multilocularis chromobox protein 1 0.0068 0.0646 0.0485
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.1396 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0222 0.2533 0.4183
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.017 0.0292
Brugia malayi Cathepsin L-like precursor 0.0222 0.2533 0.4361
Onchocerca volvulus 0.0049 0.0411 0.0424
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0041 0.0308 0.04
Entamoeba histolytica cysteine proteinase, putative 0.0222 0.2533 1
Brugia malayi mbt repeat family protein 0.0049 0.0411 0.0707
Schistosoma mansoni chromobox protein 0.0068 0.0646 0.1377
Loa Loa (eye worm) hypothetical protein 0.0103 0.1072 0.1846
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0041 0.0308 0.014
Plasmodium falciparum serine repeat antigen 4 0.0041 0.0308 0.0657
Entamoeba histolytica cysteine protease, putative 0.0114 0.121 0.4138
Brugia malayi Cathepsin L-like precursor 0.0222 0.2533 0.4361
Echinococcus multilocularis tar DNA binding protein 0.0128 0.1381 0.1232
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0275 0.3196 0.874
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0275 0.3196 0.5502
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0482 0.5734 1
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.017 0.0292
Trypanosoma cruzi cysteine peptidase, putative 0.0114 0.121 0.4445
Entamoeba histolytica cysteine protease, putative 0.0041 0.0308 0.014
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0225 0.0309
Loa Loa (eye worm) MH2 domain-containing protein 0.0137 0.149 0.2566
Echinococcus multilocularis geminin 0.0166 0.1852 0.1711
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.2533 0.4183
Brugia malayi beta-lactamase 0.0075 0.0733 0.1261
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0114 0.121 0.3005
Trypanosoma brucei RNA helicase, putative 0.0135 0.1468 0.5528
Leishmania major cathepsin L-like protease 0.0222 0.2533 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0503 0.1477
Onchocerca volvulus 0.0075 0.0733 0.0989
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0041 0.0308 0.0657
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0411 0.0707
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0114 0.121 0.3005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0222 0.2533 0.4183
Loa Loa (eye worm) hypothetical protein 0.0041 0.0308 0.053
Entamoeba histolytica cysteine proteinase, putative 0.0148 0.1631 0.6003
Mycobacterium tuberculosis Conserved protein 0.0075 0.0733 0.0439
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0041 0.0308 0.04
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0148 0.1631 0.2607
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0041 0.0308 0.0296
Onchocerca volvulus 0.0075 0.0733 0.0989
Loa Loa (eye worm) hypothetical protein 0.003 0.017 0.0292
Echinococcus multilocularis cysteine protease 0.0222 0.2533 0.2404
Brugia malayi cathepsin F-like cysteine proteinase 0.0073 0.0706 0.1216
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.0495 0.0939
Onchocerca volvulus Cathepsin L homolog 0.0222 0.2533 0.4152
Onchocerca volvulus Cathepsin L homolog 0.0222 0.2533 0.4152
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0568 0.0933
Schistosoma mansoni chromobox protein 0.0068 0.0646 0.1377
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0411 0.0697
Loa Loa (eye worm) hypothetical protein 0.0041 0.0308 0.053
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.0495 0.0762
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0041 0.0308 0.04
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0503 0.1477
Echinococcus multilocularis cathepsin b 0.0041 0.0308 0.0141
Leishmania major cathepsin L-like protease 0.0222 0.2533 1
Schistosoma mansoni hypothetical protein 0.0079 0.0777 0.1755
Plasmodium vivax vivapain-2 0.0222 0.2533 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0222 0.2533 0.2404
Loa Loa (eye worm) hypothetical protein 0.0049 0.0411 0.0707
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0411 0.0245
Brugia malayi Augmenter of liver regeneration 0.0034 0.0225 0.0387
Schistosoma mansoni hypothetical protein 0.0079 0.0777 0.1755
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.2533 0.4183
Schistosoma mansoni hypothetical protein 0.0171 0.1906 0.5016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0568 0.115
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0503 0.0781
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0079 0.0777 0.1423
Brugia malayi Cathepsin L-like precursor 0.0222 0.2533 0.4361
Entamoeba histolytica cysteine proteinase, putative 0.0114 0.121 0.4138
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0129 0.1396 0.2871
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0041 0.0308 0.053
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0225 0.0309
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0733 0.2441
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0503 0.1477
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0222 0.2533 0.2404
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0041 0.0308 0.0657
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0275 0.3196 0.874
Entamoeba histolytica cysteine protease, putative 0.0114 0.121 0.4138
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0148 0.1631 0.6212
Trypanosoma brucei cysteine peptidase C (CPC) 0.0041 0.0308 0.0657
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0276 0.0108
Brugia malayi MH2 domain containing protein 0.0137 0.149 0.2566
Loa Loa (eye worm) beta-lactamase 0.0075 0.0733 0.1261
Brugia malayi cathepsin L precursor 0.0041 0.0308 0.053
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0041 0.0308 0.04
Brugia malayi hypothetical protein 0.0018 0.0028 0.0049
Brugia malayi beta-lactamase family protein 0.0075 0.0733 0.1261
Onchocerca volvulus 0.0222 0.2533 0.4152
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0041 0.0308 0.0296
Schistosoma mansoni tar DNA-binding protein 0.0128 0.1381 0.3499
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0114 0.121 0.1872
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0041 0.0308 0.0657
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0041 0.0308 0.014
Brugia malayi Pre-SET motif family protein 0.0432 0.5126 0.8827
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0276 0.025
Loa Loa (eye worm) hypothetical protein 0.025 0.2879 0.4958
Brugia malayi fibroinase precursor 0.0041 0.0308 0.053
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0733 0.2441
Loa Loa (eye worm) hypothetical protein 0.003 0.0174 0.03
Loa Loa (eye worm) cathepsin B 0.0041 0.0308 0.053
Brugia malayi hypothetical protein 0.0038 0.0276 0.0476
Loa Loa (eye worm) cysteine protease 0.0222 0.2533 0.4361
Schistosoma mansoni hypothetical protein 0.0135 0.1468 0.3749
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.2533 0.4183
Loa Loa (eye worm) hypothetical protein 0.0073 0.0706 0.1216
Echinococcus granulosus tar DNA binding protein 0.0128 0.1381 0.2837
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0503 0.0637
Plasmodium vivax vivapain-1 0.0114 0.121 0.4445
Plasmodium falciparum serine repeat antigen 2 0.0041 0.0308 0.0657
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.1396 1
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0225 0.0309
Entamoeba histolytica cysteine protease, putative 0.0222 0.2533 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0733 0.1038
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.0495 0.0762
Entamoeba histolytica cysteine protease, putative 0.0114 0.121 0.4138
Echinococcus multilocularis tumor protein p63 0.0376 0.4439 0.4344
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0222 0.2533 1
Brugia malayi Papain family cysteine protease containing protein 0.0041 0.0308 0.053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.2533 0.4183
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0041 0.0308 0.0296
Brugia malayi Papain family cysteine protease containing protein 0.0114 0.121 0.2083
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0411 0.0697
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0075 0.0733 0.0439
Loa Loa (eye worm) hypothetical protein 0.0241 0.2778 0.4783
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.0495 0.0852
Loa Loa (eye worm) TAR-binding protein 0.0128 0.1381 0.2378
Leishmania major cathepsin L-like protease 0.0222 0.2533 1
Onchocerca volvulus 0.0222 0.2533 0.4152
Onchocerca volvulus 0.0055 0.0483 0.055
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0733 0.1626
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0041 0.0308 0.0296
Plasmodium vivax vivapain-3 0.0114 0.121 0.4445
Echinococcus granulosus GPCR family 2 0.0079 0.0777 0.1423
Loa Loa (eye worm) hypothetical protein 0.0222 0.2533 0.4361
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0411 0.0245
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0073 0.0706 0.1548
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0041 0.0308 0.0296
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0503 0.1477
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.2533 0.4183
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0041 0.0308 0.0657
Loa Loa (eye worm) hypothetical protein 0.0041 0.0308 0.053
Toxoplasma gondii exonuclease III APE 0.0057 0.0503 0.1477
Loa Loa (eye worm) ctsf protein 0.0222 0.2533 0.4361
Plasmodium falciparum serine repeat antigen 3 0.0041 0.0308 0.0657
Loa Loa (eye worm) hypothetical protein 0.0171 0.1906 0.3283
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0075 0.0733 0.0439
Plasmodium falciparum serine repeat antigen 8 0.0041 0.0308 0.0657
Leishmania major hypothetical protein, conserved 0.0075 0.0733 0.2441
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0222 0.2533 1
Brugia malayi Cathepsin L-like precursor 0.0222 0.2533 0.4361
Brugia malayi Cathepsin L-like precursor 0.0222 0.2533 0.4361
Brugia malayi cathepsin B-like cysteine proteinase 0.0041 0.0308 0.053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0222 0.2533 1
Loa Loa (eye worm) intermediate filament protein 0.003 0.017 0.0292
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0075 0.0733 0.1261
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0488 0.5808 1
Schistosoma mansoni eyes absent homolog 0.0103 0.1072 0.2607
Onchocerca volvulus 0.0041 0.0308 0.0243
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0568 0.115
Onchocerca volvulus 0.0222 0.2533 0.4152
Mycobacterium ulcerans hypothetical protein 0.0075 0.0733 0.2572
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0041 0.0308 0.04
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0041 0.0308 0.04
Echinococcus multilocularis chromobox protein 1 0.0068 0.0646 0.0485
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0225 0.0309
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0222 0.2533 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0041 0.0308 0.0296
Schistosoma mansoni hypothetical protein 0.0079 0.0777 0.1755
Echinococcus multilocularis cathepsin L cysteine protease 0.0222 0.2533 0.2404
Brugia malayi intermediate filament protein 0.003 0.017 0.0292
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0222 0.2533 0.4183
Brugia malayi cathepsin L-like precursor 0.0148 0.1631 0.2808
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0733 0.1038
Brugia malayi cathepsin Z-like cysteine proteinase 0.0041 0.0308 0.053
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0075 0.0733 0.1261
Entamoeba histolytica cysteine protease, putative 0.0114 0.121 0.4138
Entamoeba histolytica cysteine protease, putative 0.0041 0.0308 0.014
Loa Loa (eye worm) hypothetical protein 0.0038 0.0276 0.0476
Schistosoma mansoni aldehyde dehydrogenase 0.0129 0.1396 0.3541
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0041 0.0308 0.0296
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0225 0.0056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0222 0.2533 1
Schistosoma mansoni cathepsin F (C01 family) 0.0222 0.2533 0.6825
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0503 0.0866
Plasmodium falciparum serine repeat antigen 6 0.0041 0.0308 0.0657
Loa Loa (eye worm) transcription factor SMAD2 0.0137 0.149 0.2566
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0225 0.0309
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0222 0.2533 1
Echinococcus multilocularis cathepsin L 0.0114 0.121 0.1058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0222 0.2533 0.4183
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0503 0.1477
Schistosoma mansoni tar DNA-binding protein 0.0128 0.1381 0.3499
Loa Loa (eye worm) hypothetical protein 0.0041 0.0308 0.053
Toxoplasma gondii cathepsin CPC2 0.0041 0.0308 0.0657
Leishmania major hypothetical protein, conserved 0.0034 0.0225 0.0309
Schistosoma mansoni tar DNA-binding protein 0.0128 0.1381 0.3499
Trypanosoma cruzi cruzipain precursor, putative 0.0073 0.0706 0.2331
Echinococcus multilocularis cathepsin b 0.0041 0.0308 0.0141
Loa Loa (eye worm) hypothetical protein 0.0041 0.0308 0.053
Trichomonas vaginalis esterase, putative 0.0075 0.0733 0.1038
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0041 0.0308 0.0657
Plasmodium vivax unspecified product 0.0041 0.0308 0.0657
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0073 0.0706 0.1216
Entamoeba histolytica cysteine protease, putative 0.0041 0.0308 0.014
Echinococcus granulosus cathepsin l cysteine peptidase 0.0222 0.2533 0.5534
Leishmania major cysteine peptidase A (CPA) 0.0222 0.2533 1
Leishmania major cathepsin L-like protease 0.0222 0.2533 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0503 0.5
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0733 0.1626
Brugia malayi RNA binding protein 0.0128 0.1381 0.2378
Entamoeba histolytica cysteine protease, putative 0.0041 0.0308 0.014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.1396 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0222 0.2533 1
Entamoeba histolytica cysteine protease, putative 0.0114 0.121 0.4138
Brugia malayi RNA recognition motif domain containing protein 0.0128 0.1381 0.2378
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0041 0.0308 0.0296
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0275 0.3196 0.3078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.2533 0.4183
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0041 0.0308 0.0296
Toxoplasma gondii aldehyde dehydrogenase 0.0129 0.1396 0.5225
Loa Loa (eye worm) pigment dispersing factor receptor c 0.025 0.2879 0.4958
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0225 0.0309
Loa Loa (eye worm) hypothetical protein 0.0079 0.0777 0.1338
Brugia malayi Papain family cysteine protease containing protein 0.0041 0.0308 0.053
Schistosoma mansoni hypothetical protein 0.0038 0.0276 0.0308
Entamoeba histolytica cysteine protease, putative 0.0114 0.121 0.4138
Loa Loa (eye worm) hypothetical protein 0.0148 0.1631 0.2808
Loa Loa (eye worm) latrophilin receptor protein 2 0.0079 0.0777 0.1338
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0432 0.5126 0.8827
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0222 0.2533 1
Plasmodium falciparum cysteine proteinase falcipain 1 0.0114 0.121 0.4445
Brugia malayi Papain family cysteine protease containing protein 0.0222 0.2533 0.4361
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0275 0.3196 0.874
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0503 0.1477
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0568 0.0405
Trypanosoma cruzi major cysteine proteinase, putative 0.0041 0.0308 0.0657
Entamoeba histolytica cysteine proteinase 2 0.0114 0.121 0.4138
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0114 0.121 0.3005
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0706 0.2331
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0128 0.1381 0.2378
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0041 0.0308 0.053
Entamoeba histolytica cysteine protease, putative 0.0114 0.121 0.4138
Entamoeba histolytica cysteine protease, putative 0.0114 0.121 0.4138
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0276 0.0308
Brugia malayi cathepsin Z-like cysteine proteinase 0.0041 0.0308 0.053
Schistosoma mansoni tar DNA-binding protein 0.0128 0.1381 0.3499
Entamoeba histolytica cysteine proteinase 1, putative 0.0114 0.121 0.4138
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0276 0.0241
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0222 0.2533 0.4183
Brugia malayi follicle stimulating hormone receptor 0.0488 0.5808 1
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0114 0.121 0.4445
Echinococcus granulosus cathepsin l1 0.0148 0.1631 0.3422
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0503 1
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0225 0.0309
Plasmodium falciparum serine repeat antigen 7 0.0041 0.0308 0.0657
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0041 0.0308 0.0657
Entamoeba histolytica cysteine protease, putative 0.0041 0.0308 0.014
Entamoeba histolytica cysteine proteinase, putative 0.0222 0.2533 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.0495 0.0331
Leishmania major cathepsin L-like protease 0.0222 0.2533 1
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0411 0.0565
Mycobacterium leprae conserved hypothetical protein 0.0075 0.0733 0.5
Brugia malayi latrophilin 2 splice variant baaae 0.0171 0.1906 0.3283
Trypanosoma cruzi cysteine peptidase, putative 0.0222 0.2533 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.2533 0.4183
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0075 0.0733 0.2572
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0041 0.0308 0.0296
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0079 0.0777 0.1423
Schistosoma mansoni cathepsin F (C01 family) 0.0222 0.2533 0.6825
Trypanosoma cruzi cruzipain precursor, putative 0.0222 0.2533 1
Brugia malayi Heterochromatin protein 1 0.0068 0.0646 0.1113
Loa Loa (eye worm) hypothetical protein 0.0055 0.0483 0.0831
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0206 0.2335 0.5072
Schistosoma mansoni hypothetical protein 0.0166 0.1852 0.4858
Schistosoma mansoni hypothetical protein 0.0166 0.1852 0.4858
Echinococcus granulosus beta LACTamase domain containing family member 0.0075 0.0733 0.1319
Echinococcus multilocularis cathepsin L cysteine protease 0.0222 0.2533 0.2404
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.2533 0.4183
Mycobacterium tuberculosis Conserved protein 0.0075 0.0733 0.0439
Leishmania major cathepsin L-like protease 0.0222 0.2533 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0041 0.0308 0.04
Entamoeba histolytica cysteine protease, putative 0.0041 0.0308 0.014
Echinococcus granulosus chromobox protein 1 0.0068 0.0646 0.1116
Loa Loa (eye worm) RNA binding protein 0.0128 0.1381 0.2378
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0222 0.2533 1
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0041 0.0308 0.04
Mycobacterium tuberculosis Probable lipase LipD 0.0075 0.0733 0.0439
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0222 0.2533 0.4183
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0312 0.025
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0646 0.1113
Onchocerca volvulus 0.0222 0.2533 0.4152
Echinococcus multilocularis cathepsin L 0.0041 0.0308 0.0141
Schistosoma mansoni cathepsin F (C01 family) 0.0148 0.1631 0.422
Onchocerca volvulus 0.003 0.0174 0.0008
Entamoeba histolytica cysteine protease, putative 0.0114 0.121 0.4138
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0312 0.0303
Brugia malayi hypothetical protein 0.0241 0.2778 0.4783
Plasmodium falciparum serine repeat antigen 5 0.0041 0.0308 0.0657
Echinococcus granulosus cathepsin L 0.0114 0.121 0.2436
Onchocerca volvulus 0.0075 0.0733 0.0989
Toxoplasma gondii cathepsin CPC1 0.0041 0.0308 0.0657
Brugia malayi chromobox protein homolog 3 0.0038 0.0276 0.0476
Brugia malayi Pre-SET motif family protein 0.0062 0.0568 0.0978
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0225 0.0387
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0733 0.2441
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0079 0.0777 0.0618
Entamoeba histolytica cysteine protease, putative 0.0114 0.121 0.4138
Trypanosoma cruzi cysteine peptidase, putative 0.0222 0.2533 1
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0041 0.0308 0.0657
Leishmania major cathepsin L-like protease 0.0222 0.2533 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.0148 0.1631 0.2808
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0276 0.0187
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0733 0.1038
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0312 0.0303
Brugia malayi Cathepsin L-like precursor 0.0073 0.0706 0.1216
Echinococcus granulosus cysteine protease 0.0114 0.121 0.2436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.2533 0.4183
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0568 0.0405
Plasmodium vivax unspecified product 0.0073 0.0706 0.2331
Plasmodium vivax serine-repeat antigen (SERA) 0.0041 0.0308 0.0657
Loa Loa (eye worm) hypothetical protein 0.0148 0.1631 0.2808
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0275 0.3196 0.3078
Schistosoma mansoni ap endonuclease 0.0057 0.0503 0.0963
Mycobacterium ulcerans esterase/lipase LipP 0.0075 0.0733 0.2572
Loa Loa (eye worm) hypothetical protein 0.0075 0.0733 0.1261
Trypanosoma cruzi cysteine peptidase, putative 0.0222 0.2533 1
Trichomonas vaginalis set domain proteins, putative 0.0492 0.5862 1
Trypanosoma cruzi cysteine protease, putative 0.0114 0.121 0.4445
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0503 0.0866
Loa Loa (eye worm) hypothetical protein 0.0075 0.0733 0.1261
Schistosoma mansoni cathepsin S (C01 family) 0.0041 0.0308 0.04
Brugia malayi Papain family cysteine protease containing protein 0.0041 0.0308 0.053
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0646 0.0887
Trypanosoma cruzi major cysteine proteinase, putative 0.0041 0.0308 0.0657
Echinococcus granulosus cathepsin b 0.0041 0.0308 0.0324
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0041 0.0308 0.04
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0041 0.0308 0.0657
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.025 0.2879 0.4958
Entamoeba histolytica cysteine proteinase, putative 0.0114 0.121 0.4138
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0225 0.013
Plasmodium falciparum cysteine proteinase falcipain 3 0.0222 0.2533 1
Onchocerca volvulus 0.0222 0.2533 0.4152
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0308 0.0296
Echinococcus granulosus cathepsin b 0.0041 0.0308 0.0324
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0222 0.2533 0.4183
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0148 0.1631 0.2607
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.0495 0.0331
Schistosoma mansoni cathepsin s 0.0073 0.0706 0.155
Loa Loa (eye worm) hypothetical protein 0.0103 0.1072 0.1846
Loa Loa (eye worm) hypothetical protein 0.0075 0.0733 0.1261

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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