Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | intermediate filament protein | 0.0032 | 0.1093 | 0.3639 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.003 | 0.0917 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.2218 | 0.7383 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.1093 | 0.3639 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3003 | 0.3003 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.1054 | 0.351 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1191 | 0.3966 |
Brugia malayi | RNA binding protein | 0.0062 | 0.3003 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.003 | 0.0917 | 0.5 |
Brugia malayi | hypothetical protein | 0.003 | 0.0917 | 0.3052 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.3003 | 1 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0017 | 0.0109 | 0.0363 |
Echinococcus multilocularis | lamin dm0 | 0.0032 | 0.1093 | 0.1093 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.3003 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.3003 | 0.3003 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0017 | 0.0109 | 0.0363 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.1191 | 0.3966 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.3003 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.2218 | 0.7383 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.003 | 0.0917 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.3655 | 0.3655 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3003 | 0.3003 |
Echinococcus multilocularis | lamin | 0.0032 | 0.1093 | 0.1093 |
Onchocerca volvulus | 0.0032 | 0.1093 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.2218 | 0.7383 |
Echinococcus granulosus | intermediate filament protein | 0.0032 | 0.1093 | 0.1093 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.3003 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0032 | 0.1093 | 0.1093 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0032 | 0.1093 | 0.3639 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.3003 | 0.3003 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3003 | 0.3003 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.2218 | 0.7383 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3003 | 0.3003 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.3655 | 0.3655 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1191 | 0.1191 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0071 | 0.3655 | 0.3655 |
Loa Loa (eye worm) | intermediate filament protein | 0.0032 | 0.1093 | 0.3639 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0917 | 0.3052 |
Echinococcus granulosus | lamin | 0.0032 | 0.1093 | 0.1093 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.3003 | 0.3003 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0032 | 0.1093 | 0.3639 |
Schistosoma mansoni | lamin | 0.0032 | 0.1093 | 0.1093 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.3655 | 0.5 |
Schistosoma mansoni | lamin | 0.0032 | 0.1093 | 0.1093 |
Echinococcus multilocularis | musashi | 0.0032 | 0.1093 | 0.1093 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.3003 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.003 | 0.0917 | 0.5 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0071 | 0.3655 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.003 | 0.0917 | 0.5 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0071 | 0.3655 | 0.3655 |
Onchocerca volvulus | 0.0032 | 0.1093 | 0.5 | |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0071 | 0.3655 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.3655 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.3655 | 0.5 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0228 | 0.0759 |
Echinococcus granulosus | lamin dm0 | 0.0032 | 0.1093 | 0.1093 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.003 | 0.0917 | 0.5 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0071 | 0.3655 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.