Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.5405 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0073 | 0.0236 | 0.1225 |
Brugia malayi | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Brugia malayi | GH02984p | 0.0332 | 0.1857 | 0.4981 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0092 | 0.035 | 0.1262 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0196 | 0.1007 | 0.5418 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0196 | 0.1007 | 0.5418 |
Loa Loa (eye worm) | thymidylate synthase | 0.0332 | 0.1859 | 0.4987 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0196 | 0.1007 | 0.1002 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0196 | 0.1007 | 0.2702 |
Echinococcus multilocularis | sex peptide receptor | 0.0196 | 0.1007 | 0.1002 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0104 | 0.0279 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0153 | 0.0732 | 0.0727 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0196 | 0.1007 | 0.2702 |
Echinococcus granulosus | g protein coupled receptor | 0.0196 | 0.1007 | 0.5405 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0196 | 0.1007 | 0.1002 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0196 | 0.1007 | 0.2702 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0153 | 0.0732 | 0.3918 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0468 | 0.2708 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | amine GPCR | 0.0196 | 0.1007 | 0.5418 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.1002 |
Brugia malayi | G-protein coupled receptor | 0.0196 | 0.1007 | 0.2702 |
Onchocerca volvulus | 0.0153 | 0.0732 | 0.3918 | |
Brugia malayi | Dopamine receptor protein 2 | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0196 | 0.1007 | 0.5418 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0196 | 0.1007 | 0.2702 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0153 | 0.0732 | 0.0727 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | histamine h1 receptor | 0.0196 | 0.1007 | 0.5418 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.0895 | 0.4817 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0196 | 0.1007 | 0.2702 |
Leishmania major | DNA/RNA non-specific endonuclease-like protein | 0.0092 | 0.035 | 0.1262 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.0895 | 0.4817 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Giardia lamblia | Kinase, CMGC MAPK | 0.0049 | 0.0081 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0196 | 0.1007 | 0.1002 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0196 | 0.1007 | 0.1002 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.038 | 0.2042 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0196 | 0.1007 | 0.5418 |
Echinococcus granulosus | neuropeptide receptor | 0.0196 | 0.1007 | 0.5405 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Echinococcus multilocularis | dihydrofolate reductase | 0.0136 | 0.0625 | 0.062 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.038 | 0.2042 |
Trypanosoma cruzi | endonuclease G, putative | 0.0092 | 0.035 | 0.1262 |
Schistosoma mansoni | inositol monophosphatase | 0.0073 | 0.0236 | 0.1269 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0196 | 0.1007 | 0.1002 |
Brugia malayi | Inositol-1 | 0.0073 | 0.0236 | 0.0633 |
Echinococcus multilocularis | serotonin receptor | 0.0196 | 0.1007 | 0.1002 |
Schistosoma mansoni | ap endonuclease | 0.0037 | 0.0009 | 0.005 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0096 | 0.038 | 0.202 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0136 | 0.0625 | 0.333 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0153 | 0.0732 | 0.1963 |
Brugia malayi | neuropeptide F receptor | 0.0196 | 0.1007 | 0.2702 |
Brugia malayi | dihydrofolate reductase family protein | 0.0136 | 0.0625 | 0.1677 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.0581 | 0.1559 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0196 | 0.1007 | 0.1002 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0196 | 0.1007 | 0.2702 |
Echinococcus multilocularis | fmrfamide receptor | 0.0196 | 0.1007 | 0.1002 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0129 | 0.0581 | 0.3107 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0196 | 0.1007 | 0.5418 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0196 | 0.1007 | 0.2702 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Brugia malayi | follicle stimulating hormone receptor | 0.063 | 0.3727 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0196 | 0.1007 | 0.5418 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0073 | 0.0236 | 0.0231 |
Echinococcus multilocularis | geminin | 0.0179 | 0.0895 | 0.0891 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.5405 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0049 | 0.0081 | 0.0407 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0196 | 0.1007 | 0.1002 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0104 | 0.0279 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0049 | 0.0081 | 0.0434 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Brugia malayi | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0073 | 0.0236 | 0.084 |
Echinococcus granulosus | dihydrofolate reductase | 0.0136 | 0.0625 | 0.3344 |
Echinococcus granulosus | neuropeptide receptor | 0.0196 | 0.1007 | 0.5405 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0196 | 0.1007 | 0.1002 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0049 | 0.0081 | 0.039 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0153 | 0.0732 | 0.0727 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.5405 |
Schistosoma mansoni | amine GPCR | 0.0196 | 0.1007 | 0.5418 |
Toxoplasma gondii | DNA/RNA non-specific endonuclease | 0.0092 | 0.035 | 0.1275 |
Echinococcus granulosus | ectonucleotide | 0.0129 | 0.0581 | 0.3107 |
Brugia malayi | RE15519p | 0.0196 | 0.1007 | 0.2702 |
Trypanosoma brucei | protein kinase, putative | 0.0049 | 0.0081 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | hypothetical protein | 0.0332 | 0.1857 | 0.4981 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0073 | 0.0236 | 0.084 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0196 | 0.1007 | 0.5418 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0073 | 0.0236 | 0.084 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0049 | 0.0081 | 0.039 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0037 | 0.0009 | 0.0004 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0196 | 0.1007 | 0.5405 |
Schistosoma mansoni | hypothetical protein | 0.0196 | 0.1007 | 0.5418 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0049 | 0.0081 | 0.0279 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.1002 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0196 | 0.1007 | 0.5405 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0196 | 0.1007 | 0.5405 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0049 | 0.0081 | 0.039 |
Brugia malayi | Serotonin receptor | 0.0196 | 0.1007 | 0.2702 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Echinococcus multilocularis | g protein coupled receptor | 0.0196 | 0.1007 | 0.1002 |
Schistosoma mansoni | hypothetical protein | 0.0329 | 0.1839 | 0.9893 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.0081 | 0.0944 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Brugia malayi | thymidylate synthase | 0.0332 | 0.1859 | 0.4987 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0092 | 0.035 | 0.1262 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0196 | 0.1007 | 0.5418 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0468 | 0.2708 | 1 |
Brugia malayi | endonuclease G, mitochondrial precursor | 0.0092 | 0.035 | 0.0939 |
Brugia malayi | sulfakinin receptor protein | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | biogenic amine receptor | 0.0196 | 0.1007 | 0.5418 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.1002 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0196 | 0.1007 | 0.5418 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0196 | 0.1007 | 0.5405 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0037 | 0.0009 | 0.0025 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0096 | 0.038 | 0.202 |
Schistosoma mansoni | ap endonuclease | 0.0037 | 0.0009 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Echinococcus granulosus | thymidylate synthase | 0.0332 | 0.1859 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0049 | 0.0081 | 0.0265 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0049 | 0.0081 | 0.0265 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0196 | 0.1007 | 0.5405 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0196 | 0.1007 | 0.5405 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.0081 | 0.0944 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0196 | 0.1007 | 0.5405 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0196 | 0.1007 | 0.5418 |
Schistosoma mansoni | inositol transporter | 0.0037 | 0.0005 | 0.0028 |
Echinococcus granulosus | g protein coupled receptor | 0.0196 | 0.1007 | 0.5405 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0732 | 0.1963 |
Echinococcus multilocularis | allatostatin A receptor | 0.0196 | 0.1007 | 0.1002 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0332 | 0.1859 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0196 | 0.1007 | 0.5405 |
Echinococcus granulosus | sex peptide receptor | 0.0196 | 0.1007 | 0.5405 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0196 | 0.1007 | 0.5405 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0153 | 0.0732 | 0.3918 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0196 | 0.1007 | 0.5418 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0158 | 0.0767 | 0.4095 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0196 | 0.1007 | 0.5405 |
Brugia malayi | Dihydrofolate reductase | 0.0136 | 0.0625 | 0.1677 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.038 | 0.2042 |
Brugia malayi | Dopamine receptor | 0.0196 | 0.1007 | 0.2702 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0196 | 0.1007 | 0.1002 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0196 | 0.1007 | 0.2702 |
Echinococcus granulosus | g protein coupled receptor | 0.0196 | 0.1007 | 0.5405 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Brugia malayi | GnHR receptor homolog | 0.0196 | 0.1007 | 0.2702 |
Trypanosoma brucei | endonuclease G, putative | 0.0092 | 0.035 | 0.1262 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0153 | 0.0732 | 0.3918 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0073 | 0.0236 | 0.084 |
Schistosoma mansoni | myosin xvIII | 0.0196 | 0.1007 | 0.5418 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0153 | 0.0732 | 0.0727 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0136 | 0.0625 | 0.333 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0196 | 0.1007 | 0.2702 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0196 | 0.1007 | 0.1002 |
Echinococcus granulosus | serotonin receptor | 0.0196 | 0.1007 | 0.5405 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0332 | 0.1859 | 1 |
Brugia malayi | ORL1-like opioid receptor | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | amine GPCR | 0.0196 | 0.1007 | 0.5418 |
Brugia malayi | G protein-coupled receptor | 0.0196 | 0.1007 | 0.2702 |
Brugia malayi | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0096 | 0.038 | 0.1019 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0468 | 0.2708 | 1 |
Trypanosoma brucei | endonuclease G, putative | 0.0092 | 0.035 | 0.1262 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0049 | 0.0081 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0196 | 0.1007 | 0.1002 |
Schistosoma mansoni | endonuclease related | 0.0092 | 0.035 | 0.1882 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0468 | 0.2708 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0049 | 0.0081 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Echinococcus multilocularis | thymidylate synthase | 0.0332 | 0.1859 | 0.1855 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Brugia malayi | Serotonin receptor | 0.0196 | 0.1007 | 0.2702 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0332 | 0.1857 | 0.9988 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Echinococcus granulosus | somatostatin receptor | 0.0196 | 0.1007 | 0.5405 |
Brugia malayi | hypothetical protein | 0.0158 | 0.0767 | 0.2057 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0332 | 0.1859 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0049 | 0.0081 | 0.0438 |
Onchocerca volvulus | 0.0153 | 0.0732 | 0.3918 | |
Schistosoma mansoni | high-affinity choline transporter | 0.0332 | 0.1857 | 0.9988 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.063 | 0.3727 | 1 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0196 | 0.1007 | 0.5405 |
Schistosoma mansoni | biogenic amine receptor | 0.0196 | 0.1007 | 0.5418 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0196 | 0.1007 | 0.2702 |
Echinococcus multilocularis | fmrfamide receptor | 0.0196 | 0.1007 | 0.1002 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Brugia malayi | G-protein coupled receptor | 0.0196 | 0.1007 | 0.2702 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.0081 | 0.0944 |
Echinococcus granulosus | allatostatin A receptor | 0.0196 | 0.1007 | 0.5405 |
Echinococcus multilocularis | somatostatin receptor | 0.0196 | 0.1007 | 0.1002 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0196 | 0.1007 | 0.5405 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0037 | 0.0009 | 0.0025 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0196 | 0.1007 | 0.1002 |
Echinococcus granulosus | hypothetical protein | 0.0196 | 0.1007 | 0.5405 |
Schistosoma mansoni | sodium/solute symporter | 0.0037 | 0.0005 | 0.0028 |
Brugia malayi | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Echinococcus multilocularis | ectonucleotide | 0.0129 | 0.0581 | 0.0576 |
Echinococcus multilocularis | g protein coupled receptor | 0.0196 | 0.1007 | 0.1002 |
Schistosoma mansoni | hypothetical protein | 0.0196 | 0.1007 | 0.5418 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0049 | 0.0081 | 0.0217 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0196 | 0.1007 | 0.1002 |
Brugia malayi | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0196 | 0.1007 | 0.2702 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0037 | 0.0009 | 0.0022 |
Schistosoma mansoni | amine GPCR | 0.0196 | 0.1007 | 0.5418 |
Echinococcus multilocularis | serotonin receptor | 0.0196 | 0.1007 | 0.1002 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.1002 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0073 | 0.0236 | 0.2992 |
Schistosoma mansoni | hypothetical protein | 0.0196 | 0.1007 | 0.5418 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0153 | 0.0732 | 0.0727 |
Echinococcus multilocularis | neuropeptide receptor | 0.0196 | 0.1007 | 0.1002 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0196 | 0.1007 | 0.5418 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0196 | 0.1007 | 0.5418 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0732 | 0.1963 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0196 | 0.1007 | 0.5405 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0196 | 0.1007 | 0.5418 |
Schistosoma mansoni | opsin-like receptor | 0.0196 | 0.1007 | 0.5418 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0049 | 0.0081 | 0.0265 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0153 | 0.0732 | 0.0727 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0153 | 0.0732 | 0.3935 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0196 | 0.1007 | 0.1002 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.5405 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0196 | 0.1007 | 0.5418 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0153 | 0.0732 | 0.3935 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0129 | 0.0581 | 0.0576 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.5405 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0158 | 0.0767 | 1 |
Brugia malayi | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0073 | 0.0236 | 0.2992 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0196 | 0.1007 | 0.5418 |
Mycobacterium ulcerans | thymidylate synthase | 0.0332 | 0.1859 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0049 | 0.0081 | 0.0944 |
Brugia malayi | MAP kinase sur-1 | 0.0049 | 0.0081 | 0.0217 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.5405 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0196 | 0.1007 | 0.1002 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0196 | 0.1007 | 0.5405 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0196 | 0.1007 | 0.5405 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0196 | 0.1007 | 0.5418 |
Echinococcus granulosus | Endonuclease G | 0.0092 | 0.035 | 0.1859 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0049 | 0.0081 | 0.0267 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.0329 | 0.1839 | 0.4934 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0196 | 0.1007 | 0.2702 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0196 | 0.1007 | 0.5405 |
Schistosoma mansoni | hypothetical protein | 0.0196 | 0.1007 | 0.5418 |
Trypanosoma brucei | endonuclease G, putative | 0.0092 | 0.035 | 0.1262 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0104 | 0.0279 |
Brugia malayi | AKH receptor | 0.0196 | 0.1007 | 0.2702 |
Brugia malayi | Thrombospondin type 1 domain containing protein | 0.0329 | 0.1839 | 0.4934 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0153 | 0.0732 | 0.3918 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0153 | 0.0732 | 0.3935 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0049 | 0.0081 | 0.0407 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0049 | 0.0081 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Echinococcus granulosus | neuropeptide s receptor | 0.0196 | 0.1007 | 0.5405 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0196 | 0.1007 | 0.1002 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0196 | 0.1007 | 0.5418 |
Brugia malayi | Dopamine receptor protein 1 | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0196 | 0.1007 | 0.5418 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0196 | 0.1007 | 0.1002 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0196 | 0.1007 | 0.5405 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0196 | 0.1007 | 0.1002 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0049 | 0.0081 | 0.0076 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0049 | 0.0081 | 0.0438 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0196 | 0.1007 | 0.5405 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0136 | 0.0625 | 0.2618 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0096 | 0.038 | 0.1019 |
Schistosoma mansoni | biogenic amine receptor | 0.0196 | 0.1007 | 0.5418 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0073 | 0.0236 | 0.0854 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0196 | 0.1007 | 0.5418 |
Brugia malayi | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Brugia malayi | Sodium:solute symporter family protein | 0.0037 | 0.0005 | 0.0014 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.1002 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0732 | 0.1963 |
Trypanosoma cruzi | endonuclease G, putative | 0.0092 | 0.035 | 0.1262 |
Brugia malayi | Melatonin receptor type 1A | 0.0196 | 0.1007 | 0.2702 |
Onchocerca volvulus | 0.0329 | 0.1839 | 0.9893 | |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0136 | 0.0625 | 0.1677 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0158 | 0.0767 | 0.2806 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0196 | 0.1007 | 0.5405 |
Brugia malayi | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | neuropeptide receptor | 0.0196 | 0.1007 | 0.5418 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0049 | 0.0081 | 0.0411 |
Loa Loa (eye worm) | inositol-1 | 0.0073 | 0.0236 | 0.0633 |
Echinococcus multilocularis | neuropeptide receptor | 0.0196 | 0.1007 | 0.1002 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Brugia malayi | neuropeptide F receptor | 0.0196 | 0.1007 | 0.2702 |
Onchocerca volvulus | 0.0332 | 0.1859 | 1 | |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0196 | 0.1007 | 0.5418 |
Leishmania major | endonuclease G, putative | 0.0092 | 0.035 | 0.1262 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0196 | 0.1007 | 0.5405 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0196 | 0.1007 | 0.1002 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0196 | 0.1007 | 0.1002 |
Schistosoma mansoni | opsin-like receptor | 0.0196 | 0.1007 | 0.5418 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | neuropeptide receptor | 0.0196 | 0.1007 | 0.5418 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0066 | 0.0188 | 0.0965 |
Toxoplasma gondii | exonuclease III APE | 0.0037 | 0.0009 | 0.0015 |
Brugia malayi | larval opioid receptor | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | inositol monophosphatase | 0.0073 | 0.0236 | 0.1269 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0196 | 0.1007 | 0.5418 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0096 | 0.038 | 0.0375 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0096 | 0.038 | 0.0375 |
Echinococcus multilocularis | g protein coupled receptor | 0.0196 | 0.1007 | 0.1002 |
Brugia malayi | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0196 | 0.1007 | 0.5418 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0153 | 0.0732 | 0.3935 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0468 | 0.2708 | 1 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0468 | 0.2708 | 1 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0073 | 0.0236 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0196 | 0.1007 | 0.5418 |
Brugia malayi | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0073 | 0.0236 | 0.2992 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.5405 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0005 | 0.0014 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0196 | 0.1007 | 0.5418 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0196 | 0.1007 | 0.5418 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0196 | 0.1007 | 0.1002 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0049 | 0.0081 | 0.039 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0104 | 0.0279 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0196 | 0.1007 | 0.5418 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0196 | 0.1007 | 0.5405 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0153 | 0.0732 | 0.3918 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0196 | 0.1007 | 0.5405 |
Schistosoma mansoni | dihydrofolate reductase | 0.0136 | 0.0625 | 0.3363 |
Schistosoma mansoni | adenoreceptor | 0.0196 | 0.1007 | 0.5418 |
Schistosoma mansoni | opsin-like receptor | 0.0196 | 0.1007 | 0.5418 |
Echinococcus multilocularis | Endonuclease G | 0.0092 | 0.035 | 0.0345 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0073 | 0.0236 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0196 | 0.1007 | 0.1002 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0196 | 0.1007 | 0.1002 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0073 | 0.0236 | 0.1245 |
Schistosoma mansoni | amine GPCR | 0.0196 | 0.1007 | 0.5418 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0037 | 0.0009 | 0.5 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0196 | 0.1007 | 0.5405 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0332 | 0.1857 | 0.1852 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0196 | 0.1007 | 0.1002 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0196 | 0.1007 | 0.5405 |
Echinococcus granulosus | fmrfamide receptor | 0.0196 | 0.1007 | 0.5405 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0196 | 0.1007 | 0.2702 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0196 | 0.1007 | 0.5405 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0049 | 0.0081 | 0.0265 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.1002 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0196 | 0.1007 | 0.5418 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0196 | 0.1007 | 0.1002 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0196 | 0.1007 | 0.5405 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0196 | 0.1007 | 0.5418 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0049 | 0.0081 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Echinococcus granulosus | g-protein coupled receptor | 0.0196 | 0.1007 | 0.5405 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Echinococcus granulosus | geminin | 0.0179 | 0.0895 | 0.4803 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0196 | 0.1007 | 0.5418 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0196 | 0.1007 | 0.1002 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0196 | 0.1007 | 0.2702 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0136 | 0.0625 | 0.5 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0049 | 0.0081 | 0.0076 |
Brugia malayi | putative neuropeptide receptor | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Loa Loa (eye worm) | hypothetical protein | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | inositol transporter | 0.0037 | 0.0005 | 0.0028 |
Echinococcus granulosus | orexin receptor type 2 | 0.0196 | 0.1007 | 0.5405 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.1002 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0196 | 0.1007 | 0.2702 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0196 | 0.1007 | 0.5418 |
Onchocerca volvulus | 0.0196 | 0.1007 | 0.5405 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0196 | 0.1007 | 0.1002 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0049 | 0.0081 | 0.0076 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 734 uM | Binding affinity against muscarinic acetylcholine receptor from rat brain crude membrane, using [3H]-NMS (N-Methylscopolamine) as the radioligand. | ChEMBL. | 7739014 |
Ratio (binding) | = 86 | Ratio of the Ki (NMS) value to that of Ki (Oxo-M). | ChEMBL. | 7739014 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.