Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | RNA binding protein | 0.0073 | 0.5122 | 0.5122 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0053 | 0.359 | 0.6812 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0038 | 0.2486 | 0.5 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0043 | 0.2823 | 0.5 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0043 | 0.2823 | 0.5 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0316 | 0.0316 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.359 | 0.6812 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.2823 | 0.5 |
Brugia malayi | Inositol-1 | 0.0043 | 0.2823 | 0.2823 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.359 | 0.6812 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0053 | 0.359 | 0.359 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.359 | 0.6812 |
Loa Loa (eye worm) | inositol-1 | 0.0043 | 0.2823 | 0.2823 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0043 | 0.2823 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0053 | 0.359 | 0.6812 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0316 | 0.0316 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0043 | 0.2823 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0009 | 0.0316 | 0.0316 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0316 | 0.0316 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.2823 | 0.5 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0043 | 0.2823 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0073 | 0.5122 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0043 | 0.2823 | 0.5216 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0043 | 0.2823 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0073 | 0.5122 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.2823 | 0.5216 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.5122 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.5122 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.5122 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.5122 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0316 | 0.0316 |
Loa Loa (eye worm) | TAR-binding protein | 0.0073 | 0.5122 | 0.5122 |
Schistosoma mansoni | tar DNA-binding protein | 0.0073 | 0.5122 | 1 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0038 | 0.2486 | 0.5 |
Schistosoma mansoni | inositol monophosphatase | 0.0043 | 0.2823 | 0.5216 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0053 | 0.359 | 0.359 |
Brugia malayi | TAR-binding protein | 0.0073 | 0.5122 | 0.5122 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0043 | 0.2823 | 0.5216 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0073 | 0.5122 | 0.5122 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.2823 | 0.5 |
Loa Loa (eye worm) | Smad1 | 0.0009 | 0.0316 | 0.0316 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0073 | 0.5122 | 0.5122 |
Brugia malayi | Smad1 | 0.0009 | 0.0316 | 0.0316 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0009 | 0.0316 | 0.0316 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0053 | 0.359 | 0.6812 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0043 | 0.2823 | 0.5 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0043 | 0.2823 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0053 | 0.359 | 0.6812 |
Loa Loa (eye worm) | RNA binding protein | 0.0073 | 0.5122 | 0.5122 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.