TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 426.405 | Formula: C21H22F4N2O3
H donors: 2 H acceptors: 2 LogP: 3.85 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: COc1ccc(cc1C(CC(C(F)(F)F)(Cc1cc2c([nH]1)c[n+](cc2)[O-])O)(C)C)F
InChi: 1S/C21H22F4N2O3/c1-19(2,16-9-14(22)4-5-18(16)30-3)12-20(28,21(23,24)25)10-15-8-13-6-7-27(29)11-17(13)26-15/h4-9,11,26,28H,10,12H2,1-3H3
InChiKey: YXQHFQSWIAZVFJ-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	nuclear receptor subfamily 3, group C, member 2	Starlite/ChEMBL	References
Homo sapiens	progesterone receptor	Starlite/ChEMBL	References
Homo sapiens	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0042	0.2462	0.2401
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.002	0.0858	0.0858
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2462	0.2401
Plasmodium vivax	ataxin-2 like protein, putative	0.0031	0.1655	0.5
Brugia malayi	hypothetical protein	0.002	0.0865	0.0791
Loa Loa (eye worm)	DR-78	0.002	0.0858	0.0784
Brugia malayi	nuclear hormone receptor family member nhr-6	0.002	0.0858	0.0784
Schistosoma mansoni	cpg binding protein	0.0033	0.1866	0.1866
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0042	0.2462	0.2462
Loa Loa (eye worm)	hypothetical protein	0.002	0.0858	0.0784
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0022	0.103	0.103
Schistosoma mansoni	cpg binding protein	0.0032	0.1735	0.1735
Echinococcus granulosus	TGF beta signal transducer SmadC	0.0009	0.008	0.008
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0042	0.2462	0.2401
Echinococcus granulosus	Ataxin 2 N terminaldomain containing protein	0.0014	0.0426	0.0426
Brugia malayi	nuclear receptor RXR	0.002	0.0858	0.0784
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0042	0.2462	0.2401
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.002	0.0858	0.0784
Brugia malayi	Steroid receptor seven-up type 2	0.0042	0.2462	0.2401
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0032	0.1735	0.1668
Brugia malayi	latrophilin 2 splice variant baaae	0.0035	0.1977	0.1912
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0042	0.2462	0.2462
Brugia malayi	hypothetical protein	0.0022	0.103	0.0957
Brugia malayi	Nuclear hormone receptor E75	0.002	0.0858	0.0784
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0042	0.2462	0.2462
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0042	0.2462	0.2462
Schistosoma mansoni	coup transcription factor	0.0042	0.2462	0.2462
Onchocerca volvulus	Huntingtin homolog	0.0135	0.9273	1
Toxoplasma gondii	histone lysine methyltransferase SET1	0.006	0.38	1
Echinococcus multilocularis	mothers against decapentaplegic 5	0.0009	0.008	0.008
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0042	0.2462	0.2401
Schistosoma mansoni	hypothetical protein	0.0035	0.1977	0.1977
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0042	0.2462	0.2462
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0042	0.2462	0.2462
Brugia malayi	nuclear hormone receptor	0.0042	0.2462	0.2401
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0042	0.2462	0.2401
Echinococcus multilocularis	cpg binding protein	0.0033	0.1866	0.1866
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0042	0.2462	0.2462
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0042	0.2462	0.2462
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0016	0.0607	0.0607
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.002	0.0858	0.0858
Loa Loa (eye worm)	nuclear receptor NHR-67	0.002	0.0858	0.0784
Loa Loa (eye worm)	histone methyltransferase	0.001	0.0141	0.0061
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0042	0.2462	0.2462
Loa Loa (eye worm)	transcription factor SMAD2	0.0132	0.9022	0.9014
Echinococcus multilocularis	ecdysone induced protein 78C	0.0042	0.2462	0.2462
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0042	0.2462	0.2462
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.002	0.0858	0.0784
Schistosoma mansoni	nuclear hormone receptor	0.002	0.0858	0.0858
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0022	0.103	0.103
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0022	0.103	0.103
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0042	0.2462	0.2401
Schistosoma mansoni	TGF-beta signal transducer Smad2	0.0009	0.008	0.008
Echinococcus granulosus	smad	0.0009	0.008	0.008
Echinococcus multilocularis	Smad4	0.0009	0.008	0.008
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2462	0.2401
Loa Loa (eye worm)	hypothetical protein	0.002	0.0858	0.0784
Schistosoma mansoni	RAR-like nuclear receptor	0.0042	0.2462	0.2462
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2462	0.2401
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.002	0.0858	0.0858
Echinococcus multilocularis	GPCR, family 2	0.0016	0.0607	0.0607
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0067	0.4323	0.4323
Echinococcus granulosus	ecdysone induced protein 78C	0.0042	0.2462	0.2462
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0042	0.2462	0.2462
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0042	0.2462	0.2462
Echinococcus multilocularis	smad	0.0009	0.008	0.008
Onchocerca volvulus		0.0042	0.2462	0.1906
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.002	0.0858	0.0858
Echinococcus multilocularis	Ataxin 2, N terminal,domain containing protein	0.0014	0.0426	0.0426
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0051	0.3158	0.3102
Schistosoma mansoni	nuclear receptor	0.002	0.0858	0.0858
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0042	0.2462	0.2401
Loa Loa (eye worm)	hypothetical protein	0.0022	0.103	0.0957
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0044	0.2607	0.2607
Trypanosoma cruzi	PAB1-binding protein , putative	0.0031	0.1655	0.5
Loa Loa (eye worm)	hypothetical protein	0.002	0.0858	0.0784
Schistosoma mansoni	Smad4	0.0009	0.008	0.008
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0042	0.2462	0.2401
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2462	0.2401
Brugia malayi	nuclear receptor NHR-88	0.002	0.0858	0.0784
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2462	0.2401
Loa Loa (eye worm)	hypothetical protein	0.0135	0.9273	0.9267
Schistosoma mansoni	smad1 5 8 and	0.0009	0.008	0.008
Loa Loa (eye worm)	MH2 domain-containing protein	0.0132	0.9022	0.9014
Schistosoma mansoni	transcription factor LCR-F1	0.0044	0.2607	0.2607
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0042	0.2462	0.2401
Onchocerca volvulus	Bile acid receptor homolog	0.0042	0.2462	0.1906
Brugia malayi	nuclear receptor NHR-88	0.0042	0.2462	0.2401
Entamoeba histolytica	hypothetical protein	0.0044	0.2607	0.5
Brugia malayi	nuclear hormone receptor family member odr-7	0.002	0.0858	0.0784
Echinococcus granulosus	Smad4	0.0009	0.008	0.008
Schistosoma mansoni	cpg binding protein	0.0033	0.1866	0.1866
Brugia malayi	hypothetical protein	0.0044	0.2607	0.2547
Schistosoma mansoni	zinc finger protein	0.002	0.0858	0.0858
Loa Loa (eye worm)	hypothetical protein	0.002	0.0858	0.0784
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0042	0.2462	0.2401
Echinococcus multilocularis	nuclear receptor nhr 48	0.002	0.0858	0.0858
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2462	0.2401
Brugia malayi	F/Y-rich N-terminus family protein	0.001	0.0132	0.0052
Brugia malayi	orphan nuclear receptor NR2E1	0.002	0.0858	0.0784
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0016	0.0607	0.0607
Schistosoma mansoni	smad	0.0009	0.008	0.008
Entamoeba histolytica	hypothetical protein	0.0044	0.2607	0.5
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0016	0.0607	0.0607
Plasmodium falciparum	ataxin-2 like protein, putative	0.0031	0.1655	0.5
Loa Loa (eye worm)	hypothetical protein	0.0022	0.103	0.0957
Schistosoma mansoni	thyroid hormone receptor	0.0042	0.2462	0.2462
Loa Loa (eye worm)	hypothetical protein	0.002	0.0858	0.0784
Brugia malayi	steroid hormone receptor	0.0042	0.2462	0.2401
Loa Loa (eye worm)	hypothetical protein	0.002	0.0858	0.0784
Loa Loa (eye worm)	hypothetical protein	0.002	0.0858	0.0784
Entamoeba histolytica	hypothetical protein	0.0044	0.2607	0.5
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0042	0.2462	0.2462
Brugia malayi	Nuclear hormone receptor-like 1	0.0022	0.103	0.0957
Onchocerca volvulus	Huntingtin homolog	0.0135	0.9273	1
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.001	0.0141	0.0141
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0022	0.103	0.0957
Loa Loa (eye worm)	hypothetical protein	0.002	0.0858	0.0784
Trypanosoma brucei	PAB1-binding protein , putative	0.0031	0.1655	0.5
Brugia malayi	Latrophilin receptor protein 2	0.0016	0.0607	0.0531
Schistosoma mansoni	thyroid hormone receptor	0.0042	0.2462	0.2462
Trypanosoma cruzi	PAB1-binding protein , putative	0.0031	0.1655	0.5
Loa Loa (eye worm)	hypothetical protein	0.0022	0.103	0.0957
Brugia malayi	conserved hypotetical protein	0.002	0.0858	0.0784
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.002	0.0858	0.0858
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0042	0.2462	0.2401
Plasmodium falciparum	ataxin-2 like protein, putative	0.0031	0.1655	0.5
Loa Loa (eye worm)	hypothetical protein	0.002	0.0858	0.0784
Echinococcus granulosus	cpg binding protein	0.0033	0.1866	0.1866
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0042	0.2462	0.2462
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0016	0.0607	0.0531
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0042	0.2462	0.2462
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0042	0.2462	0.2462
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0042	0.2462	0.2401
Echinococcus granulosus	mothers against decapentaplegic 5	0.0009	0.008	0.008
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0042	0.2462	0.2401
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0042	0.2462	0.1906
Loa Loa (eye worm)	nuclear hormone receptor	0.002	0.0858	0.0784
Loa Loa (eye worm)	hypothetical protein	0.002	0.0858	0.0784
Schistosoma mansoni	nuclear receptor nhr-48	0.002	0.0858	0.0858
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0607	0.0531
Brugia malayi	tailless protein	0.002	0.0858	0.0784
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.002	0.0858	0.0858
Loa Loa (eye worm)	hypothetical protein	0.0022	0.103	0.0957
Leishmania major	hypothetical protein, conserved	0.0031	0.1655	0.5
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2462	0.2401
Loa Loa (eye worm)	hypothetical protein	0.0022	0.103	0.0957
Brugia malayi	hypothetical protein	0.002	0.0858	0.0784
Brugia malayi	hypothetical protein	0.0022	0.103	0.0957
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0022	0.103	0.103
Brugia malayi	nuclear receptor RXR	0.0022	0.103	0.0957
Brugia malayi	ecdysteroid receptor	0.0042	0.2462	0.2401
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0042	0.2462	0.2401
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0042	0.2462	0.2462
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0042	0.2462	0.2401
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0042	0.2462	0.2401
Echinococcus multilocularis	TGF beta signal transducer SmadC	0.0009	0.008	0.008
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0051	0.3158	0.3102
Echinococcus granulosus	Nuclear hormone receptor HR96	0.002	0.0858	0.0858
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0042	0.2462	0.2462
Brugia malayi	Nuclear hormone receptor-like 1	0.0022	0.103	0.0957
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0042	0.2462	0.2462
Schistosoma mansoni	hypothetical protein	0.0014	0.0426	0.0426
Entamoeba histolytica	hypothetical protein	0.0044	0.2607	0.5
Loa Loa (eye worm)	hypothetical protein	0.0135	0.9273	0.9267
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0042	0.2462	0.2462
Schistosoma mansoni	smad1 5 8 and	0.0009	0.008	0.008
Loa Loa (eye worm)	hypothetical protein	0.0031	0.1655	0.1587
Echinococcus granulosus	thyroid hormone receptor alpha	0.002	0.0858	0.0858
Schistosoma mansoni	nuclear hormone receptor	0.002	0.0858	0.0858
Loa Loa (eye worm)	hypothetical protein	0.002	0.0858	0.0784
Echinococcus multilocularis	FTZ F1 alpha	0.0042	0.2462	0.2462
Brugia malayi	hypothetical protein	0.0135	0.9273	0.9267
Schistosoma mansoni	nuclear receptor	0.002	0.0858	0.0858
Brugia malayi	nuclear hormone receptor	0.002	0.0858	0.0784
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0042	0.2462	0.2401
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0042	0.2462	0.2401
Brugia malayi	CXXC zinc finger family protein	0.0032	0.1735	0.1668
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2462	0.2401
Echinococcus granulosus	nuclear receptor nhr 48	0.002	0.0858	0.0858
Brugia malayi	ecdysone receptor	0.002	0.0858	0.0784
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.002	0.0858	0.0858
Brugia malayi	Nuclear hormone receptor E75	0.002	0.0858	0.0784
Schistosoma mansoni	hypothetical protein	0.0044	0.2607	0.2607
Schistosoma mansoni	hypothetical protein	0.0016	0.0607	0.0607
Echinococcus granulosus	FTZ F1 alpha	0.0042	0.2462	0.2462
Echinococcus granulosus	GPCR family 2	0.0016	0.0607	0.0607
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.002	0.0858	0.0858
Brugia malayi	MH2 domain containing protein	0.0132	0.9022	0.9014
Brugia malayi	photoreceptor-specific nuclear receptor	0.0042	0.2462	0.2401
Brugia malayi	Nuclear hormone receptor-like 1	0.0042	0.2462	0.2401
Loa Loa (eye worm)	steroid hormone receptor	0.0042	0.2462	0.2401
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.001	0.0141	0.0141
Schistosoma mansoni	retinoic acid receptor RXR	0.0042	0.2462	0.2462
Schistosoma mansoni	smad1 5 8 and	0.0009	0.008	0.008
Loa Loa (eye worm)	hypothetical protein	0.0051	0.3158	0.3102
Brugia malayi	hypothetical protein	0.002	0.0858	0.0784
Schistosoma mansoni	hypothetical protein	0.0016	0.0607	0.0607
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0042	0.2462	0.2401
Schistosoma mansoni	hypothetical protein	0.0016	0.0607	0.0607
Loa Loa (eye worm)	hypothetical protein	0.002	0.0858	0.0784
Onchocerca volvulus		0.0032	0.1735	0.1041
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0051	0.3158	0.3102
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0042	0.2462	0.2401
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.002	0.0858	0.0858
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0044	0.2607	0.2607
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0016	0.0607	0.0607
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0042	0.2462	0.2462
Schistosoma mansoni	nuclear hormone receptor	0.0042	0.2462	0.2462
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0016	0.0607	0.0531
Loa Loa (eye worm)	hypothetical protein	0.002	0.0858	0.0784
Brugia malayi	nuclear receptor NHR-67	0.002	0.0858	0.0784
Schistosoma mansoni	hypothetical protein	0.0016	0.0607	0.0607
Echinococcus granulosus	Nuclear hormone receptor HR96	0.002	0.0858	0.0858
Brugia malayi	hypothetical protein	0.0031	0.1655	0.1587
Onchocerca volvulus	Protein ultraspiracle homolog	0.0042	0.2462	0.1906
Loa Loa (eye worm)	hypothetical protein	0.0035	0.1977	0.1912

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)		Transrepression activity at glucocorticoid receptor in HFF assessed as inhibition of IL-1-induced IL-6 production after 18 to 24 hrs by ELISA	ChEMBL.	20735001
IC50 (binding)	= 860 nM	Binding affinity to glucocorticoid receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled Dexamethasone by fluorescence polarization microplate assay	ChEMBL.	20735001
IC50 (binding)	> 2000 nM	Binding affinity to progesterone receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled RU-486 by fluorescence polarization microplate assay	ChEMBL.	20735001
IC50 (binding)	> 2000 nM	Binding affinity to mineralocorticoid receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled Dexamethasone by fluorescence polarization microplate assay	ChEMBL.	20735001

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1254821

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1183011