Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | trypanothione reductase | 0.004 | 0.074 | 0.2402 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0077 | 0.0049 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0563 | 0.0548 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0755 | 0.2041 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0134 | 0.2872 | 0.8263 |
Brugia malayi | Thioredoxin reductase | 0.004 | 0.074 | 0.2005 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0077 | 0.0061 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0033 | 0.0585 | 0.2241 |
Onchocerca volvulus | 0.0041 | 0.0755 | 1 | |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0091 | 0.19 | 0.3148 |
Echinococcus multilocularis | tar DNA binding protein | 0.0134 | 0.2872 | 0.2861 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.3464 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0077 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.2316 | 0.6626 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0641 | 0.0626 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0033 | 0.0585 | 0.7379 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.093 | 0.0915 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0077 | 0.0061 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0641 | 0.0626 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0091 | 0.19 | 0.3148 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0077 | 0.0061 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0014 | 0.0149 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0983 | 0.2712 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0161 | 0.3464 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0033 | 0.0585 | 0.2241 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0123 | 0.2612 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0102 | 0.2131 | 0.3562 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0077 | 0.0057 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.001 | 0.0065 | 0.0024 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0123 | 0.2612 | 0.7498 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0755 | 0.2048 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0077 | 0.0057 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0041 | 0.0755 | 0.109 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0123 | 0.2612 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0102 | 0.2131 | 0.7408 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.006 | 0.0044 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.001 | 0.0065 | 0.0024 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.093 | 0.2561 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0755 | 0.2041 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0123 | 0.2612 | 0.2601 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0983 | 0.0969 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0077 | 0.0061 |
Echinococcus granulosus | geminin | 0.0189 | 0.4101 | 0.4091 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0077 | 0.0049 |
Mycobacterium ulcerans | beta-lactamase | 0.0041 | 0.0755 | 0.2461 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0077 | 0.0061 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0123 | 0.2612 | 1 |
Plasmodium vivax | glutathione reductase, putative | 0.004 | 0.074 | 0.976 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0755 | 0.289 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0123 | 0.2612 | 0.2601 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0077 | 0.0057 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0641 | 0.0273 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.093 | 0.0915 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0755 | 0.2041 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0077 | 0.0049 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0077 | 0.0061 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0033 | 0.0585 | 0.2241 |
Toxoplasma gondii | thioredoxin reductase | 0.004 | 0.074 | 0.555 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.093 | 0.0915 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0033 | 0.0585 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0077 | 0.0061 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0051 | 0.0983 | 0.0969 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0033 | 0.0585 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0041 | 0.0755 | 0.2461 |
Onchocerca volvulus | 0.0041 | 0.0755 | 1 | |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0041 | 0.0753 | 0.0738 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0641 | 0.0273 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0033 | 0.0585 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.006 | 0.0044 |
Brugia malayi | 6-phosphofructokinase | 0.0123 | 0.2612 | 0.75 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.0605 | 0.059 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0077 | 0.0057 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0033 | 0.0585 | 0.2241 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0077 | 0.0061 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0983 | 0.0969 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0123 | 0.2612 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0134 | 0.2872 | 0.2861 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0134 | 0.2872 | 0.8261 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0014 | 0.0149 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0983 | 0.0969 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0161 | 0.3464 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0077 | 0.0057 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0077 | 0.0061 |
Plasmodium vivax | thioredoxin reductase, putative | 0.004 | 0.074 | 0.976 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0102 | 0.2131 | 0.3562 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0077 | 0.0061 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0014 | 0.0149 | 0.0133 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.0563 | 0.1478 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0033 | 0.0585 | 0.2241 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0033 | 0.0585 | 0.1772 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0755 | 0.2041 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0033 | 0.0585 | 0.4095 |
Echinococcus multilocularis | GPCR, family 2 | 0.0051 | 0.0983 | 0.0969 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0033 | 0.0585 | 0.7202 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0041 | 0.0755 | 0.109 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0033 | 0.0585 | 0.2241 |
Schistosoma mansoni | hypothetical protein | 0.0189 | 0.4101 | 0.4091 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0123 | 0.2612 | 0.4428 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0123 | 0.2612 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0755 | 0.2048 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0077 | 0.0057 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0755 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0077 | 0.0049 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.093 | 0.0915 |
Brugia malayi | beta-lactamase | 0.0041 | 0.0755 | 0.2048 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.093 | 0.0915 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.1215 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.093 | 0.2555 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0123 | 0.2612 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0041 | 0.0755 | 0.109 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0041 | 0.0755 | 0.109 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0755 | 0.109 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0077 | 0.0061 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0033 | 0.0585 | 0.2241 |
Loa Loa (eye worm) | thioredoxin reductase | 0.004 | 0.074 | 0.1998 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0051 | 0.0983 | 0.0969 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0051 | 0.0983 | 0.2718 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0077 | 0.0057 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.0563 | 0.1485 |
Brugia malayi | 6-phosphofructokinase | 0.0123 | 0.2612 | 0.75 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0077 | 0.0061 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0014 | 0.0149 | 0.5 |
Toxoplasma gondii | ABC1 family protein | 0.0041 | 0.0755 | 0.5686 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0123 | 0.2612 | 1 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0033 | 0.0585 | 0.4095 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0755 | 0.289 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0014 | 0.0149 | 0.0569 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0755 | 0.074 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.004 | 0.074 | 0.1063 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0077 | 0.0049 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0077 | 0.0049 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.026 | 0.5713 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0077 | 0.0061 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.0755 | 0.2461 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0077 | 0.0061 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.2872 | 0.2861 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0077 | 0.0061 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0041 | 0.0755 | 0.2048 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0755 | 0.074 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0123 | 0.2612 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0755 | 0.289 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0077 | 0.0061 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.2872 | 0.2861 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0077 | 0.0049 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0077 | 0.0061 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.2316 | 0.2304 |
Echinococcus granulosus | GPCR family 2 | 0.0051 | 0.0983 | 0.0969 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0014 | 0.0149 | 0.0569 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0077 | 0.0049 |
Plasmodium falciparum | thioredoxin reductase | 0.004 | 0.074 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0077 | 0.0049 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.2872 | 0.2861 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.093 | 0.0915 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0077 | 0.0057 |
Echinococcus multilocularis | geminin | 0.0189 | 0.4101 | 0.4091 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0091 | 0.19 | 0.6167 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0077 | 0.0057 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0755 | 0.289 |
Loa Loa (eye worm) | TAR-binding protein | 0.0134 | 0.2872 | 0.8261 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.0755 | 0.2461 |
Mycobacterium ulcerans | lipase LipD | 0.0041 | 0.0755 | 0.2461 |
Brugia malayi | TAR-binding protein | 0.0134 | 0.2872 | 0.8263 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0077 | 0.0049 |
Brugia malayi | glutathione reductase | 0.004 | 0.074 | 0.2005 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0123 | 0.2612 | 0.2601 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0051 | 0.0983 | 0.0969 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0077 | 0.0061 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0123 | 0.2612 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0077 | 0.0061 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0641 | 0.0273 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0077 | 0.0057 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0077 | 0.0061 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0755 | 0.289 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0161 | 0.3464 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0641 | 0.0273 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0641 | 0.0626 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0077 | 0.0061 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0014 | 0.0149 | 0.0133 |
Plasmodium falciparum | glutathione reductase | 0.004 | 0.074 | 1 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0014 | 0.0149 | 0.0268 |
Mycobacterium ulcerans | hypothetical protein | 0.0041 | 0.0755 | 0.2461 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0051 | 0.0983 | 0.0969 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0123 | 0.2612 | 0.2601 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0077 | 0.0057 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0051 | 0.0983 | 0.2718 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0077 | 0.0061 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0077 | 0.0057 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.2872 | 0.2861 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0123 | 0.2612 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0755 | 0.109 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.093 | 0.0915 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0102 | 0.2131 | 0.3562 |
Mycobacterium tuberculosis | Probable reductase | 0.0091 | 0.19 | 0.3148 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0033 | 0.0585 | 0.4095 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0041 | 0.0755 | 0.109 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0077 | 0.0061 |
Loa Loa (eye worm) | beta-lactamase | 0.0041 | 0.0755 | 0.2041 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.004 | 0.074 | 0.2402 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0041 | 0.0755 | 0.2461 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0077 | 0.0057 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0755 | 0.109 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0077 | 0.0061 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0041 | 0.0753 | 0.0738 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0077 | 0.0057 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0033 | 0.0585 | 0.7202 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0077 | 0.0061 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0077 | 0.0061 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0123 | 0.2612 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0077 | 0.0061 |
Brugia malayi | phosphofructokinase | 0.0123 | 0.2612 | 0.75 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0077 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0755 | 0.2041 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0641 | 0.1712 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0077 | 0.0061 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0041 | 0.0755 | 0.2041 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0077 | 0.0061 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0091 | 0.19 | 0.3148 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0123 | 0.2612 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.2872 | 0.2861 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0033 | 0.0585 | 0.7379 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0755 | 0.2041 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0091 | 0.19 | 0.3148 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0605 | 0.059 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0077 | 0.0049 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0051 | 0.0983 | 0.2712 |
Schistosoma mansoni | hypothetical protein | 0.0189 | 0.4101 | 0.4091 |
Brugia malayi | RNA binding protein | 0.0134 | 0.2872 | 0.8263 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0123 | 0.2612 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0077 | 0.0049 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0605 | 0.059 |
Loa Loa (eye worm) | RNA binding protein | 0.0134 | 0.2872 | 0.8261 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0077 | 0.0057 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0077 | 0.0057 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0091 | 0.19 | 0.3148 |
Leishmania major | trypanothione reductase | 0.004 | 0.074 | 0.2402 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0755 | 0.2461 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0077 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0077 | 0.0049 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0041 | 0.0755 | 0.074 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0641 | 0.0626 |
Loa Loa (eye worm) | glutathione reductase | 0.004 | 0.074 | 0.1998 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0077 | 0.0049 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0041 | 0.0755 | 0.109 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0077 | 0.0057 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0068 | 0.138 | 0.1366 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0983 | 0.0969 |
Trichomonas vaginalis | esterase, putative | 0.0041 | 0.0755 | 0.289 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0041 | 0.0755 | 0.074 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0077 | 0.0049 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.011 | 0.2316 | 0.6629 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0077 | 0.0057 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0755 | 0.2461 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0041 | 0.0755 | 0.109 |
Onchocerca volvulus | 0.0041 | 0.0755 | 1 | |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0077 | 0.0061 |
Loa Loa (eye worm) | phosphofructokinase | 0.0123 | 0.2612 | 0.7498 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0077 | 0.0057 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.0605 | 0.059 |
Onchocerca volvulus | 0.0032 | 0.0563 | 0.7174 | |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0123 | 0.2612 | 0.7498 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: Inhibitors of TCP-1 ring complex (TRiC) of Methanococcus maripaludis (MmCpn): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488991] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.