Detailed information for compound 1183337

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 408.498 | Formula: C18H32N8O3
  • H donors: 6 H acceptors: 5 LogP: -2.23 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: NCCC(CC[C@H]1OC([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N)NCCCCN
  • InChi: 1S/C18H32N8O3/c19-6-1-2-8-22-11(5-7-20)3-4-12-14(27)15(28)18(29-12)26-10-25-13-16(21)23-9-24-17(13)26/h9-12,14-15,18,22,27-28H,1-8,19-20H2,(H2,21,23,24)/t11?,12-,14-,15-,18?/m1/s1
  • InChiKey: QWWYIMOIEWLIOP-WFIMNSBASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens spermidine synthase Starlite/ChEMBL References
Rattus norvegicus Spermidine synthase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium vivax spermidine synthase, putative Get druggable targets OG5_127074 All targets in OG5_127074
Brugia malayi Spermidine synthase Get druggable targets OG5_127074 All targets in OG5_127074
Candida albicans spermidine synthase Get druggable targets OG5_127074 All targets in OG5_127074
Leishmania major spermidine synthase Get druggable targets OG5_127074 All targets in OG5_127074
Trypanosoma brucei spermidine synthase Get druggable targets OG5_127074 All targets in OG5_127074
Leishmania infantum spermidine synthase, putative Get druggable targets OG5_127074 All targets in OG5_127074
Trypanosoma cruzi spermidine synthase, putative Get druggable targets OG5_127074 All targets in OG5_127074
Plasmodium knowlesi spermidine synthase, putative Get druggable targets OG5_127074 All targets in OG5_127074
Mycobacterium ulcerans spermidine synthase Get druggable targets OG5_127074 All targets in OG5_127074
Plasmodium falciparum spermidine synthase Get druggable targets OG5_127074 All targets in OG5_127074
Candida albicans spermidine synthase Get druggable targets OG5_127074 All targets in OG5_127074
Plasmodium berghei spermidine synthase, putative Get druggable targets OG5_127074 All targets in OG5_127074
Echinococcus granulosus spermidine synthase Get druggable targets OG5_127074 All targets in OG5_127074
Leishmania braziliensis spermidine synthase, putative Get druggable targets OG5_127074 All targets in OG5_127074
Leishmania mexicana spermidine synthase, putative Get druggable targets OG5_127074 All targets in OG5_127074
Trypanosoma cruzi spermidine synthase, putative Get druggable targets OG5_127074 All targets in OG5_127074
Mycobacterium tuberculosis Probable spermidine synthase SpeE (putrescine aminopropyltransferase) (aminopropyltransferase) (SPDSY) Get druggable targets OG5_127074 All targets in OG5_127074
Plasmodium yoelii spermidine synthase-related Get druggable targets OG5_127074 All targets in OG5_127074
Echinococcus multilocularis spermidine synthase Get druggable targets OG5_127074 All targets in OG5_127074
Trypanosoma cruzi spermidine synthase, putative Get druggable targets OG5_127074 All targets in OG5_127074
Loa Loa (eye worm) spermidine synthase Get druggable targets OG5_127074 All targets in OG5_127074
Trypanosoma brucei gambiense spermidine synthase, putative Get druggable targets OG5_127074 All targets in OG5_127074
Trypanosoma cruzi spermidine synthase, putative Get druggable targets OG5_127074 All targets in OG5_127074
Leishmania donovani spermidine synthase, putative Get druggable targets OG5_127074 All targets in OG5_127074
Trypanosoma congolense spermidine synthase Get druggable targets OG5_127074 All targets in OG5_127074
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Candida albicans spermine synthase Spermidine synthase   302 aa 289 aa 45.3 %
Candida albicans spermine synthase Spermidine synthase   302 aa 289 aa 45.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Peroxidase homolog 0.0009 0.0004 0.0005
Echinococcus multilocularis serine:threonine protein kinase N2 0.0048 0.0083 0.0336
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Brugia malayi nuclear hormone receptor family member nhr-6 0.0087 0.0163 0.053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0021 0.0029 0.0093
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0027 0.0041 0.013
Brugia malayi G-protein coupled receptor 0.0017 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0027
Toxoplasma gondii diacylglycerol kinase, putative 0.0046 0.008 0.0347
Brugia malayi protein kinase C II. 0.0188 0.037 0.1203
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0008 0.0002 0.0003
Schistosoma mansoni vav2 0.005 0.0087 0.0086
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0009 0.0169
Schistosoma mansoni RAR-like nuclear receptor 0.0185 0.0362 0.0362
Brugia malayi ABC transporter family protein 0.0012 0.0009 0.0028
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0014 0.0014 0.0054
Loa Loa (eye worm) hypothetical protein 0.0087 0.0163 0.053
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0009 0.0004 0.0003
Loa Loa (eye worm) G-protein coupled receptor 0.0017 0.0019 0.0062
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0019 0.0078
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0087 0.0163 0.0664
Onchocerca volvulus 0.0009 0.0004 0.0006
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0116 0.0221 0.0902
Onchocerca volvulus 0.0116 0.0221 0.0672
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Onchocerca volvulus 0.0017 0.0019 0.0053
Brugia malayi hypothetical protein 0.0087 0.0163 0.053
Trichomonas vaginalis AGC family protein kinase 0.0051 0.009 0.2059
Echinococcus multilocularis transmembrane protease serine 3 0.0015 0.0016 0.0065
Echinococcus granulosus Rac GTPase activating protein 1 0.0046 0.008 0.0323
Echinococcus multilocularis protein kinase c iota type 0.0148 0.0287 0.1171
Loa Loa (eye worm) hypothetical protein 0.0176 0.0344 0.112
Echinococcus multilocularis neuropeptide s receptor 0.0017 0.0019 0.0078
Echinococcus multilocularis glycoprotein Antigen 5 0.0015 0.0016 0.0065
Toxoplasma gondii NAC domain-containing protein 0.0011 0.0009 0.0036
Trichomonas vaginalis glutathione reductase, putative 0.0014 0.0014 0.0276
Onchocerca volvulus Phospholipase A2 homolog 0.0234 0.0463 0.1411
Echinococcus granulosus protein kinase C gamma type 0.0129 0.0249 0.1015
Schistosoma mansoni protein tyrosine phosphatase 0.0009 0.0004 0.0003
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0008 0.0002 0.0023
Brugia malayi hypothetical protein 0.0009 0.0004 0.0011
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0017 0.0019 0.0078
Trypanosoma cruzi trans-sialidase, putative 0.0016 0.0019 0.0251
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0025 0.0036 0.0147
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0019 0.0078
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0047 0.008 0.026
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0068 0.0124 0.0505
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0016 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0009 0.0154
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0009 0.0004 0.0014
Entamoeba histolytica P-glycoprotein 5, putative 0.0012 0.0009 0.0203
Echinococcus multilocularis Rac GTPase activating protein 1 0.0046 0.008 0.0323
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0009 0.0036
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0016 0.0016
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0014 0.0183
Brugia malayi multidrug resistance protein 3 0.0012 0.0009 0.0028
Onchocerca volvulus 0.0015 0.0016 0.0044
Schistosoma mansoni multidrug resistance protein 0.0012 0.0009 0.0009
Echinococcus multilocularis unc 13 (munc13) 0.005 0.0088 0.0357
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Onchocerca volvulus Neuropeptide F receptor homolog 0.0017 0.0019 0.0053
Trichomonas vaginalis taga, putative 0.0012 0.0009 0.0169
Trypanosoma brucei trans-sialidase, putative 0.0016 0.0019 0.0251
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.0052
Echinococcus multilocularis multidrug resistance protein 1 0.0008 0.0002 0.0006
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0185 0.0362 0.0362
Trichomonas vaginalis abcb9, putative 0.0012 0.0009 0.0169
Echinococcus granulosus alkaline phosphatase 0.0208 0.041 0.1673
Echinococcus granulosus myotubularin protein 13 0.005 0.0087 0.0352
Onchocerca volvulus 0.018 0.0353 0.1075
Schistosoma mansoni nuclear receptor nhr-48 0.0087 0.0163 0.0163
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0009 0.0036
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0009 0.0004 0.0014
Onchocerca volvulus 0.0015 0.0016 0.0044
Brugia malayi Matrixin family protein 0.0038 0.0063 0.0204
Toxoplasma gondii MAPEG family protein 0.1124 0.228 1
Onchocerca volvulus 0.0009 0.0004 0.0006
Schistosoma mansoni growth hormone secretagogue receptor 0.0017 0.0019 0.0019
Brugia malayi Protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0185 0.0362 0.118
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0008 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0047 0.008 0.026
Echinococcus granulosus Nuclear hormone receptor HR96 0.0087 0.0163 0.0664
Plasmodium falciparum multidrug resistance protein 1 0.0012 0.0009 0.012
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0019 0.0078
Loa Loa (eye worm) hypothetical protein 0.0098 0.0184 0.06
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0362 0.0724 0.2359
Echinococcus granulosus twitchin 0.0008 0.0001 0.0003
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0012 0.0009 0.0038
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0019 0.0078
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0217 0.0429 1
Echinococcus multilocularis somatostatin receptor 0.0017 0.0019 0.0078
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0117 0.0225 0.3094
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0362 0.0724 0.2955
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0016 0.0019 0.0058
Trypanosoma brucei trans-sialidase, putative 0.0016 0.0019 0.0251
Loa Loa (eye worm) animal heme peroxidase 0.0009 0.0004 0.0011
Schistosoma mansoni pcd6 interacting protein-related 0.0009 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Plasmodium vivax subtilisin-like protease 1 0.007 0.0129 0.1768
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0248 0.0492 0.6772
Trypanosoma brucei protein tyrosine phosphatase 1 0.0009 0.0004 0.0048
Schistosoma mansoni amine GPCR 0.0017 0.0019 0.0019
Echinococcus multilocularis tar DNA binding protein 0.0027 0.0041 0.0164
Schistosoma mansoni amine GPCR 0.0017 0.0019 0.0019
Brugia malayi Matrixin family protein 0.0038 0.0063 0.0204
Schistosoma mansoni multidrug resistance protein 0.0012 0.0009 0.0009
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0017 0.0019 0.0062
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0098 0.0184 0.0751
Brugia malayi Nuclear hormone receptor-like 1 0.0098 0.0184 0.06
Onchocerca volvulus Peroxidase homolog 0.0009 0.0004 0.0005
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0017 0.0019 0.0078
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0008 0.0002 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.002 0.0025 0.0025
Echinococcus granulosus Diacylglycerol kinase theta 0.0046 0.008 0.0323
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Plasmodium falciparum basic transcription factor 3b, putative 0.0011 0.0009 0.0112
Brugia malayi hypothetical protein 0.0017 0.0019 0.0062
Brugia malayi Protein kinase domain containing protein 0.0362 0.0725 0.2362
Schistosoma mansoni lipoxygenase 0.1207 0.2449 0.2449
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0035 0.0056 0.0771
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0009 0.0169
Brugia malayi orphan nuclear receptor NR2E1 0.0087 0.0163 0.053
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.0133 0.0257 0.105
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0055 0.0097 0.0097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0019 0.0078
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Echinococcus granulosus multidrug resistance protein 1 0.0008 0.0002 0.0006
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0017 0.0019 0.0078
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0087 0.0163 0.0493
Onchocerca volvulus 0.0009 0.0004 0.0006
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0009 0.0004 0.0014
Entamoeba histolytica P-glycoprotein-2 0.0012 0.0009 0.0203
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0185 0.0362 0.1478
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.0019
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0009 0.0004 0.0003
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0038 0.0063 0.0063
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.0133 0.0257 0.4184
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0058
Onchocerca volvulus 0.0017 0.0019 0.0053
Brugia malayi Protein kinase domain containing protein 0.0048 0.0082 0.0267
Schistosoma mansoni protein kinase C mu 0.015 0.0292 0.0291
Echinococcus granulosus sodium:myo inositol cotransporter 0.0453 0.0911 0.3718
Onchocerca volvulus 0.0036 0.0058 0.0172
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0078 0.0145 0.0589
Schistosoma mansoni sodium/solute symporter 0.0116 0.0221 0.0221
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0009 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0017 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Schistosoma mansoni high-affinity choline transporter 0.0116 0.0221 0.0221
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0008 0.0002 0.0023
Brugia malayi hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) AGC/AKT protein kinase 0.0051 0.009 0.0291
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0009 0.0004 0.0014
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0009 0.0004 0.0014
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0098 0.0184 0.0184
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0009 0.0004 0.0011
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0009 0.0169
Onchocerca volvulus 0.0009 0.0004 0.0006
Echinococcus granulosus g protein coupled receptor 0.0017 0.0019 0.0078
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0185 0.0362 0.0362
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0083 0.0082
Entamoeba histolytica P-glyco protein 6, putative 0.0012 0.0009 0.0203
Onchocerca volvulus Peroxidasin homolog 0.001 0.0006 0.0013
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0012 0.001 0.0009
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0016 0.0016
Brugia malayi bHLH-PAS transcription factor 0.0024 0.0033 0.0107
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Brugia malayi beta-NAC-like protein 0.0011 0.0009 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Giardia lamblia NADH oxidase lateral transfer candidate 0.0014 0.0014 0.0321
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Onchocerca volvulus 0.0017 0.0019 0.0053
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Onchocerca volvulus 0.0017 0.0019 0.0053
Loa Loa (eye worm) hypothetical protein 0.0116 0.0221 0.072
Brugia malayi putative neuropeptide receptor NPR1 0.0017 0.0019 0.0062
Brugia malayi MH2 domain containing protein 0.009 0.0169 0.0551
Onchocerca volvulus 0.0009 0.0004 0.0006
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0016 0.0019 0.0251
Echinococcus granulosus g protein coupled receptor 0.0017 0.0019 0.0078
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0009 0.0004 0.0014
Onchocerca volvulus 0.0054 0.0096 0.0287
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0046 0.008 0.0323
Schistosoma mansoni cpg binding protein 0.0012 0.001 0.001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.002 0.0025 0.0101
Onchocerca volvulus 0.0087 0.0163 0.0493
Loa Loa (eye worm) hypothetical protein 0.0185 0.0362 0.118
Trypanosoma brucei trypanothione reductase 0.004 0.0068 0.0926
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0098 0.0184 0.06
Onchocerca volvulus 0.0015 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.0052
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0055 0.0097 0.0315
Onchocerca volvulus 0.0009 0.0004 0.0006
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0016 0.0016
Brugia malayi Matrixin family protein 0.0038 0.0063 0.0204
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0009 0.0004 0.0048
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0016 0.0019 0.0251
Leishmania major squalene monooxygenase-like protein 0.0066 0.0119 0.1637
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0019 0.0078
Brugia malayi hypothetical protein 0.0115 0.0219 0.0712
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Brugia malayi ORL1-like opioid receptor 0.0017 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.018 0.0353 0.115
Onchocerca volvulus 0.0009 0.0004 0.0006
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0009 0.0169
Echinococcus granulosus Mastin 0.0015 0.0016 0.0065
Loa Loa (eye worm) hypothetical protein 0.0046 0.008 0.0258
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0248 0.0492 0.6772
Brugia malayi RNA recognition motif domain containing protein 0.0027 0.0041 0.013
Onchocerca volvulus 0.0017 0.0019 0.0053
Onchocerca volvulus 0.0015 0.0016 0.0044
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0009 0.0004 0.0014
Leishmania major tyrosine specific protein phosphatase, putative 0.0009 0.0004 0.0048
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0016 0.0016
Schistosoma mansoni unc-13 (munc13) 0.005 0.0088 0.0088
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0046 0.008 0.0258
Brugia malayi Protein-tyrosine phosphatase 1 0.0009 0.0004 0.0011
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0009 0.0004 0.0014
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0019 0.0078
Brugia malayi Protein kinase domain containing protein 0.0048 0.0083 0.0268
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0106 0.0202 0.3182
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0185 0.0362 0.0362
Echinococcus multilocularis spermidine synthase 0.0363 0.0726 0.2964
Onchocerca volvulus 0.0009 0.0004 0.0006
Schistosoma mansoni neuropeptide receptor 0.0017 0.0019 0.0019
Schistosoma mansoni biogenic amine receptor 0.0017 0.0019 0.0019
Echinococcus granulosus geminin 0.0056 0.0099 0.0401
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0048 0.0083 0.0268
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0185 0.0362 0.1478
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0185 0.0362 0.1478
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0046 0.008 0.0258
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0014 0.0014 0.5
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0017 0.0019 0.0019
Entamoeba histolytica P-glycoprotein-2, putative 0.0012 0.0009 0.0203
Leishmania major trypanothione reductase 0.004 0.0068 0.0926
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0016 0.0019 0.0251
Echinococcus granulosus alpha 1A adrenergic receptor 0.0017 0.0019 0.0078
Schistosoma mansoni microtubule-associated protein tau 0.0295 0.0588 0.0588
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0008 0.0002 0.0007
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0024
Loa Loa (eye worm) hypothetical protein 0.1422 0.2889 0.942
Onchocerca volvulus 0.0009 0.0004 0.0006
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0063 0.0113 0.2633
Plasmodium vivax glutathione reductase, putative 0.004 0.0068 0.0926
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0009 0.0036
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0014 0.0014 0.0058
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0009 0.0004 0.0081
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0014 0.0014 0.0183
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.0019
Echinococcus granulosus protein tyrosine phosphatase n9 0.0009 0.0004 0.0014
Echinococcus granulosus enteropeptidase 0.0015 0.0016 0.0065
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.001 0.0005 0.0062
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0019 0.0078
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0012 0.0009 0.0028
Echinococcus multilocularis survival motor neuron protein 1 0.0176 0.0344 0.1403
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0185 0.0362 0.118
Onchocerca volvulus Protein ultraspiracle homolog 0.0185 0.0362 0.1104
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0009 0.0169
Brugia malayi Nuclear hormone receptor E75 0.0087 0.0163 0.053
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0009 0.0004 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0185 0.0362 0.118
Brugia malayi Spermidine synthase 0.0363 0.0726 0.2366
Loa Loa (eye worm) hypothetical protein 0.0087 0.0163 0.053
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0217 0.0429 1
Loa Loa (eye worm) matrixin family protein 0.0085 0.0158 0.0514
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0185 0.0362 0.1478
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0009 0.0169
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Brugia malayi Calcitonin receptor-like protein seb-1 0.0016 0.0019 0.0058
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0015 0.0016 0.0052
Echinococcus multilocularis lipoxygenase domain containing protein 0.0217 0.0429 0.1748
Brugia malayi ecdysteroid receptor 0.0185 0.0362 0.118
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0087 0.0163 0.053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Brugia malayi Matrixin family protein 0.0092 0.0174 0.0565
Brugia malayi Animal haem peroxidase family protein 0.0009 0.0004 0.0011
Echinococcus multilocularis multidrug resistance protein 1 0.0012 0.0009 0.0036
Onchocerca volvulus 0.0017 0.0019 0.0053
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Schistosoma mansoni zinc finger protein 0.0087 0.0163 0.0163
Schistosoma mansoni thyroid hormone receptor 0.0185 0.0362 0.0362
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0019 0.0078
Mycobacterium ulcerans short chain dehydrogenase 0.0149 0.029 0.4706
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0017 0.0019 0.0062
Trypanosoma cruzi transcription factor btf3, putative 0.0011 0.0009 0.0112
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0453 0.0911 0.3718
Schistosoma mansoni tar DNA-binding protein 0.0027 0.0041 0.004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0105 0.02 0.0652
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0068 0.0124 0.0505
Plasmodium falciparum thioredoxin reductase 0.0014 0.0014 0.0183
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.0019
Brugia malayi larval opioid receptor 0.0017 0.0019 0.0062
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.037 0.0369
Schistosoma mansoni steroid hormone receptor ad4bp 0.0185 0.0362 0.0362
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0048 0.0083 0.0268
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0016 0.0019 0.0251
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.0133 0.0257 0.105
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0019 0.0078
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0009 0.0004 0.0014
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0009 0.0169
Entamoeba histolytica diacylglycerol kinase, putative 0.0046 0.008 0.1848
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0009 0.0036
Loa Loa (eye worm) matrix metalloproteinase 0.0038 0.0063 0.0204
Onchocerca volvulus Chorion peroxidase homolog 0.0009 0.0004 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0051 0.009 0.2059
Onchocerca volvulus 0.0012 0.001 0.0025
Entamoeba histolytica protein kinase, putative 0.0048 0.0083 0.1923
Brugia malayi RhoGEF domain containing protein 0.0046 0.008 0.0258
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.002 0.0025 0.008
Onchocerca volvulus 0.0152 0.0296 0.09
Schistosoma mansoni protein tyrosine phosphatase 0.0009 0.0004 0.0003
Loa Loa (eye worm) thioredoxin reductase 0.004 0.0068 0.0219
Loa Loa (eye worm) hypothetical protein 0.0046 0.008 0.0258
Brugia malayi nuclear hormone receptor family member odr-7 0.0087 0.0163 0.053
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0019 0.0019
Loa Loa (eye worm) melatonin receptor type 1A 0.0017 0.0019 0.0062
Trichomonas vaginalis mercuric reductase, putative 0.0014 0.0014 0.0276
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0014 0.0183
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0009 0.0004 0.0011
Mycobacterium tuberculosis Probable oxidoreductase 0.0102 0.0194 0.3058
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0008 0.0002 0.0023
Trypanosoma cruzi transcription factor btf3, putative 0.0011 0.0009 0.0112
Leishmania major protein kinase, putative 0.001 0.0005 0.0062
Loa Loa (eye worm) CYP4Cod1 0.0017 0.0019 0.0061
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0048 0.0083 0.0336
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0185 0.0362 0.1478
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Onchocerca volvulus 0.0009 0.0004 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0003
Onchocerca volvulus 0.0009 0.0004 0.0006
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0012 0.0009 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0345 0.0345
Schistosoma mansoni smdr2 0.0012 0.0009 0.0009
Trypanosoma brucei transcription factor BTF3, putative 0.0011 0.0009 0.0112
Onchocerca volvulus Dual oxidase homolog 0.0009 0.0004 0.0005
Onchocerca volvulus 0.0009 0.0004 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.0019
Echinococcus granulosus sodium:glucose cotransporter 0.0453 0.0911 0.3718
Echinococcus multilocularis transcription factor btf3 0.0011 0.0009 0.0033
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0009 0.0004 0.0014
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0019 0.0078
Trichomonas vaginalis AGC family protein kinase 0.0051 0.009 0.2059
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Schistosoma mansoni biogenic amine receptor 0.0017 0.0019 0.0019
Toxoplasma gondii hypothetical protein 0.004 0.0067 0.0292
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.002 0.0025 0.0025
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0017 0.0019 0.0078
Echinococcus multilocularis allatostatin A receptor 0.0017 0.0019 0.0078
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Echinococcus multilocularis orexin receptor type 2 0.0017 0.0019 0.0078
Onchocerca volvulus 0.0017 0.0019 0.0053
Echinococcus multilocularis sterol regulatory element binding protein 0.0055 0.0097 0.0395
Schistosoma mansoni tar DNA-binding protein 0.0027 0.0041 0.004
Echinococcus granulosus G protein coupled receptor 139 0.0017 0.0019 0.0078
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0017 0.0019 0.0078
Brugia malayi Phospholipase A2 family protein 0.0496 0.0999 0.3255
Loa Loa (eye worm) blistered cuticle protein 3 0.0009 0.0004 0.0011
Schistosoma mansoni neuropeptide receptor 0.0017 0.0019 0.0019
Brugia malayi Immunoglobulin I-set domain containing protein 0.0082 0.0153 0.0498
Trichomonas vaginalis guanylate cyclase, putative 0.0008 0.0002 0.0003
Schistosoma mansoni rab6-interacting 0.0217 0.0429 0.0428
Trypanosoma cruzi squalene monooxygenase, putative 0.0066 0.0119 0.1637
Loa Loa (eye worm) hypothetical protein 0.0361 0.0722 0.2352
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0019 0.0078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.0019
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0009 0.0169
Schistosoma mansoni hypothetical protein 0.0046 0.008 0.0079
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0016 0.0016
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0139 0.0269 0.1096
Echinococcus multilocularis Polycystic kidney disease protein 0.0217 0.0429 0.1748
Trichomonas vaginalis pten, drome, putative 0.0009 0.0004 0.0045
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0124 0.0124
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0048 0.0083 0.0268
Loa Loa (eye worm) glutathione reductase 0.004 0.0068 0.0219
Brugia malayi Hemopexin family protein 0.0054 0.0096 0.031
Brugia malayi Protein kinase domain containing protein 0.0048 0.0083 0.0268
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0012 0.0009 0.0169
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0009 0.0169
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0014 0.0014 0.0183
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0009 0.0169
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0248 0.0492 0.6772
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.0019
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0009 0.0004 0.0014
Plasmodium falciparum glutathione reductase 0.004 0.0068 0.0926
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0014 0.0014 0.0183
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0185 0.0362 0.118
Echinococcus granulosus g-protein coupled receptor 0.0017 0.0019 0.0078
Onchocerca volvulus 0.0009 0.0004 0.0006
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0017 0.0019 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0185 0.0362 0.118
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0009 0.0004 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0082 0.0082
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Brugia malayi Trypsin-like protease protein 5 0.0015 0.0016 0.0052
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Echinococcus multilocularis neuropeptide FF receptor 2 0.0017 0.0019 0.0078
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Echinococcus granulosus somatostatin receptor 0.0017 0.0019 0.0078
Trichomonas vaginalis AGC family protein kinase 0.0048 0.0083 0.1894
Echinococcus multilocularis ATP binding cassette sub family B 0.0012 0.0009 0.0034
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0014 0.0014 0.0043
Brugia malayi Blistered cuticle protein 3 0.0009 0.0004 0.0011
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0014 0.0014 0.0183
Toxoplasma gondii aldehyde dehydrogenase 0.0068 0.0124 0.0542
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0005
Schistosoma mansoni polycystin 1-related 0.0217 0.0429 0.0428
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0009 0.0004 0.0011
Echinococcus multilocularis geminin 0.0056 0.0099 0.0401
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0019 0.0259
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0012 0.0009 0.012
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0016 0.0016
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0115 0.0219 0.0712
Brugia malayi follicle stimulating hormone receptor 0.0017 0.0019 0.0062
Leishmania major protein kinase, putative 0.001 0.0005 0.0062
Schistosoma mansoni rab6-interacting 0.0217 0.0429 0.0428
Loa Loa (eye worm) RNA binding protein 0.0027 0.0041 0.013
Onchocerca volvulus 0.0009 0.0004 0.0006
Brugia malayi hypothetical protein 0.0015 0.0016 0.0052
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.0052
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0821 0.1661 0.6782
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0014 0.0183
Brugia malayi Serotonin receptor 0.0017 0.0019 0.0062
Schistosoma mansoni retinoic acid receptor RXR 0.0918 0.186 0.186
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0204
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Onchocerca volvulus Matrilysin homolog 0.0085 0.0158 0.0478
Schistosoma mansoni cpg binding protein 0.0013 0.0012 0.0011
Onchocerca volvulus Tyrosine kinase homolog 0.0077 0.0142 0.0429
Schistosoma mansoni tar DNA-binding protein 0.0027 0.0041 0.004
Brugia malayi Thioredoxin reductase 0.004 0.0068 0.0219
Loa Loa (eye worm) hypothetical protein 0.0102 0.0194 0.0632
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0016 0.0016
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0017 0.0019 0.0078
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0009 0.0036
Schistosoma mansoni histamine h1 receptor 0.0017 0.0019 0.0019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0217 0.0429 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0012 0.001 0.0039
Loa Loa (eye worm) hypothetical protein 0.0087 0.0163 0.053
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0017 0.0019 0.0019
Schistosoma mansoni nuclear hormone receptor 0.0087 0.0163 0.0163
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0009 0.0004 0.0014
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0069 0.0125 0.0125
Onchocerca volvulus Matrix metalloproteinase homolog 0.0085 0.0158 0.0478
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Plasmodium vivax spermidine synthase, putative 0.0363 0.0726 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0019 0.0078
Echinococcus granulosus aryl hydrocarbon receptor 0.0008 0.0002 0.0007
Brugia malayi CHE-14 protein 0.0055 0.0097 0.0315
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0009 0.0004 0.0003
Schistosoma mansoni hypothetical protein 0.0011 0.0008 0.0008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0087 0.0163 0.0664
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0046 0.008 0.1827
Brugia malayi hypothetical protein 0.0017 0.0019 0.0062
Toxoplasma gondii histone lysine methyltransferase SET1 0.0023 0.0033 0.0142
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0016 0.0019 0.0251
Loa Loa (eye worm) hypothetical protein 0.018 0.0353 0.115
Trypanosoma cruzi trans-sialidase, putative 0.0016 0.0019 0.0251
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0009 0.0004 0.0003
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0063 0.0113 0.2599
Loa Loa (eye worm) hypothetical protein 0.0115 0.0219 0.0712
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0048 0.0083 0.0336
Brugia malayi Trypsin family protein 0.0015 0.0016 0.0052
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Plasmodium falciparum LCCL domain-containing protein 0.0217 0.0429 0.5899
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0072 0.0986
Echinococcus multilocularis hypothetical protein 0.0009 0.0004 0.0014
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.015 0.0292 0.0949
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0185 0.0362 0.1478
Brugia malayi Animal haem peroxidase family protein 0.001 0.0006 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0185 0.0362 0.118
Plasmodium falciparum glutathione reductase 0.0014 0.0014 0.0183
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0047 0.008 0.1173
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0019 0.0078
Echinococcus multilocularis RNA directed DNA polymerase 0.0078 0.0145 0.0589
Schistosoma mansoni multidrug resistance protein 0.0012 0.0009 0.0009
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0008 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0217 0.0429 0.1396
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0046 0.008 0.0323
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Echinococcus granulosus lipoxygenase domain containing protein 0.0217 0.0429 0.1748
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0217 0.0429 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) DR-78 0.0087 0.0163 0.053
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0014 0.0183
Loa Loa (eye worm) hypothetical protein 0.0185 0.0362 0.118
Echinococcus granulosus transmembrane protease serine 3 0.0015 0.0016 0.0065
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0025 0.0036 0.0036
Mycobacterium tuberculosis Conserved hypothetical protein 0.0131 0.0252 0.4012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0362 0.0724 0.2955
Brugia malayi protein kinase C3,putative 0.0101 0.0192 0.0625
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0133 0.0257 0.3541
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0014 0.0183
Echinococcus multilocularis solute carrier family 5 0.0453 0.0911 0.3718
Schistosoma mansoni neuropeptide f receptor 76f 0.0017 0.0019 0.0019
Brugia malayi Trypsin family protein 0.0015 0.0016 0.0052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Loa Loa (eye worm) multidrug resistance protein 3 0.0012 0.0009 0.0028
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0014 0.0183
Echinococcus multilocularis serotonin receptor 0.0017 0.0019 0.0078
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.0133 0.0257 0.3541
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0083 0.0082
Trichomonas vaginalis AGC family protein kinase 0.0051 0.009 0.2059
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0016 0.0016
Echinococcus multilocularis lipoxygenase domain containing protein 0.0217 0.0429 0.1748
Schistosoma mansoni protein kinase C mu 0.0046 0.008 0.0079
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Trichomonas vaginalis guanylate cyclase, putative 0.0008 0.0002 0.0003
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0208 0.041 0.1673
Echinococcus multilocularis 0.0009 0.0004 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.0019
Echinococcus granulosus ecdysone induced protein 78C 0.0185 0.0362 0.1478
Loa Loa (eye worm) hypothetical protein 0.0185 0.0362 0.118
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Brugia malayi hypothetical protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) TYRA-2 protein 0.0017 0.0019 0.0062
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.1207 0.2449 1
Toxoplasma gondii AGC kinase 0.0048 0.0083 0.0361
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0009 0.0036
Loa Loa (eye worm) protein tyrosine phosphatase 0.0009 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0217 0.0429 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0149 0.029 0.463
Entamoeba histolytica diacylglycerol kinase, putative 0.0046 0.008 0.1848
Onchocerca volvulus 0.0217 0.0429 0.1307
Brugia malayi nuclear receptor NHR-67 0.0087 0.0163 0.053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Trichomonas vaginalis AGC family protein kinase 0.0051 0.009 0.2059
Echinococcus multilocularis serine threonine protein kinase 0.0129 0.0249 0.1015
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0046 0.008 0.0258
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.0052
Brugia malayi hypothetical protein 0.0217 0.0429 0.1396
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0009 0.0169
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0016 0.0019 0.0251
Echinococcus multilocularis peroxidasin 0.0012 0.001 0.0038
Onchocerca volvulus Matrilysin homolog 0.0038 0.0063 0.0187
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0016 0.0019 0.0251
Echinococcus granulosus cpg binding protein 0.0013 0.0012 0.0046
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0009 0.0004 0.0003
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0012 0.001 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0082 0.0082
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Brugia malayi hypothetical protein 0.0017 0.0019 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0185 0.0362 0.118
Trichomonas vaginalis AGC family protein kinase 0.0051 0.009 0.2059
Echinococcus granulosus unc 13 munc13 0.005 0.0088 0.0357
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0009 0.0154
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0015 0.0016 0.0065
Brugia malayi Protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0019 0.0019
Trypanosoma brucei trans-sialidase, putative 0.0016 0.0019 0.0251
Schistosoma mansoni alkaline phosphatase 0.0208 0.041 0.041
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Trypanosoma cruzi squalene monooxygenase, putative 0.0066 0.0119 0.1637
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Schistosoma mansoni hypothetical protein 0.0054 0.0096 0.0095
Brugia malayi hypothetical protein 0.0017 0.0019 0.0062
Onchocerca volvulus 0.0217 0.0429 0.1307
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0014 0.0014 0.0183
Schistosoma mansoni diacylglycerol kinase theta 0.0046 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) nuclear receptor nhr-7B 0.1509 0.3067 1
Loa Loa (eye worm) hypothetical protein 0.0087 0.0163 0.053
Entamoeba histolytica P-glycoprotein-1 0.0012 0.0009 0.0203
Echinococcus granulosus thioredoxin glutathione reductase 0.004 0.0068 0.0275
Echinococcus multilocularis protein dispatched 1 0.0055 0.0097 0.0395
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0014 0.0014 0.0183
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.0052
Onchocerca volvulus 0.0017 0.0019 0.0053
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0217 0.0429 1
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0015 0.0016 0.0016
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0098 0.0184 0.0751
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0217 0.0429 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Schistosoma mansoni survival motor neuron protein 0.0036 0.0058 0.0058
Onchocerca volvulus 0.0009 0.0004 0.0005
Onchocerca volvulus 0.0017 0.0019 0.0053
Echinococcus granulosus NDR protein kinase 0.0048 0.0083 0.0336
Brugia malayi Serotonin receptor 0.0017 0.0019 0.0062
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0009 0.0169
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Schistosoma mansoni peroxidasin 0.0009 0.0004 0.0003
Loa Loa (eye worm) G-protein coupled receptor 0.0017 0.0019 0.0062
Brugia malayi Melatonin receptor type 1A 0.0017 0.0019 0.0062
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0009 0.0036
Echinococcus granulosus g protein coupled receptor 0.0017 0.0019 0.0078
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Echinococcus granulosus sodium:glucose cotransporter 2 0.0453 0.0911 0.3718
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Entamoeba histolytica hypothetical protein 0.0046 0.008 0.1848
Schistosoma mansoni opsin-like receptor 0.0017 0.0019 0.0019
Brugia malayi photoreceptor-specific nuclear receptor 0.0185 0.0362 0.118
Loa Loa (eye worm) nuclear hormone receptor 0.0087 0.0163 0.053
Echinococcus granulosus survival motor neuron protein 1 0.0176 0.0344 0.1403
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Giardia lamblia Protein tyrosine phosphatase 0.0009 0.0004 0.0091
Mycobacterium tuberculosis Probable dehydrogenase 0.0092 0.0173 0.2712
Brugia malayi hypothetical protein 0.0107 0.0204 0.0662
Brugia malayi Dopamine receptor protein 1 0.0017 0.0019 0.0062
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0019 0.0078
Brugia malayi hypothetical protein 0.0115 0.0219 0.0712
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0009 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0019 0.0078
Brugia malayi diacylglycerol kinase 0.0046 0.008 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0083 0.0082
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Leishmania major spermidine synthase 0.0363 0.0726 1
Brugia malayi Animal haem peroxidase family protein 0.0009 0.0004 0.0011
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0124 0.2012
Echinococcus multilocularis protein kinase c epsilon type 0.0188 0.037 0.1508
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.002 0.0025 0.008
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0185 0.0362 0.118
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0017 0.0019 0.0062
Echinococcus multilocularis FTZ F1 alpha 0.0185 0.0362 0.1478
Brugia malayi hypothetical protein 0.0009 0.0004 0.0011
Brugia malayi hypothetical protein 0.0098 0.0184 0.06
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Brugia malayi Trypsin family protein 0.0015 0.0016 0.0052
Loa Loa (eye worm) hypothetical protein 0.0123 0.0237 0.0772
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0102 0.0194 0.3058
Schistosoma mansoni patched 1 0.0055 0.0097 0.0097
Schistosoma mansoni peroxidasin 0.0011 0.0007 0.0007
Echinococcus granulosus spermidine synthase 0.0363 0.0726 0.2964
Loa Loa (eye worm) hypothetical protein 0.0087 0.0163 0.053
Schistosoma mansoni biogenic amine receptor 0.0017 0.0019 0.0019
Onchocerca volvulus 0.0017 0.0019 0.0053
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0009 0.0004 0.0014
Loa Loa (eye worm) transcription factor SMAD2 0.009 0.0169 0.0551
Trichomonas vaginalis AGC family protein kinase 0.0048 0.0083 0.1894
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0009 0.0004 0.0014
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0918 0.186 0.7596
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.0019
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0012 0.001 0.0039
Loa Loa (eye worm) hypothetical protein 0.0098 0.0184 0.06
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0102 0.0194 0.9625
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0185 0.0362 0.118
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.0133 0.0257 0.0838
Schistosoma mansoni hypothetical protein 0.0056 0.0099 0.0098
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0046 0.008 0.0258
Echinococcus granulosus solute carrier family 5 0.0453 0.0911 0.3718
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.001 0.0005 0.0062
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0009 0.0036
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Schistosoma mansoni coup transcription factor 0.0185 0.0362 0.0362
Brugia malayi PAS domain containing protein 0.0032 0.005 0.0162
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0009 0.0004 0.0003
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0019 0.0019
Schistosoma mansoni protein tyrosine phosphatase 0.0009 0.0004 0.0003
Onchocerca volvulus 0.0017 0.0019 0.0053
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0014 0.0014 0.0217
Trichomonas vaginalis abcb9, putative 0.0012 0.0009 0.0169
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0009 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.001 0.0005 0.0062
Echinococcus multilocularis thioredoxin glutathione reductase 0.004 0.0068 0.0275
Brugia malayi diacylglycerol kinase 0.0046 0.008 0.0258
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0019 0.0078
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0009 0.0004 0.0014
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0014 0.0183
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.005 0.0088 0.0357
Loa Loa (eye worm) hypothetical protein 0.0234 0.0463 0.1507
Loa Loa (eye worm) hypothetical protein 0.005 0.0088 0.0285
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0009 0.0004 0.0014
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0016 0.0016
Schistosoma mansoni neuropeptide receptor 0.0017 0.0019 0.0019
Trypanosoma brucei trans-sialidase, putative 0.0016 0.0019 0.0251
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0106 0.0202 0.3279
Toxoplasma gondii subtilisin SUB1 0.007 0.0129 0.0563
Trypanosoma brucei cytochrome P450, putative 0.0017 0.0019 0.0259
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0063 0.0113 0.2599
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0019 0.0061
Echinococcus granulosus tar DNA binding protein 0.0027 0.0041 0.0164
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0017 0.0019 0.0306
Brugia malayi hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) animal heme peroxidase 0.0009 0.0004 0.0011
Loa Loa (eye worm) nuclear receptor NHR-67 0.0087 0.0163 0.053
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0185 0.0362 0.1478
Onchocerca volvulus 0.0087 0.0163 0.0493
Echinococcus multilocularis RUN 0.0217 0.0429 0.1748
Loa Loa (eye worm) hypothetical protein 0.0087 0.0163 0.053
Loa Loa (eye worm) hypothetical protein 0.0185 0.0362 0.118
Echinococcus multilocularis raf serine:threonine protein kinase 0.0046 0.008 0.0323
Loa Loa (eye worm) neuropeptide F receptor 0.0017 0.0019 0.0062
Onchocerca volvulus 0.0009 0.0004 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.0098 0.0184 0.06
Loa Loa (eye worm) hypothetical protein 0.0012 0.001 0.003
Schistosoma mansoni amine GPCR 0.0017 0.0019 0.0019
Echinococcus multilocularis enteropeptidase 0.0015 0.0016 0.0065
Echinococcus multilocularis cpg binding protein 0.0013 0.0012 0.0046
Schistosoma mansoni cpg binding protein 0.0013 0.0012 0.0011
Echinococcus granulosus intestinal type alkaline phosphatase 0.0208 0.041 0.1673
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0068 0.0124 0.1897
Schistosoma mansoni hypothetical protein 0.0108 0.0206 0.0205
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0009 0.0169
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0116 0.0221 0.0969
Echinococcus granulosus peptide allatostatin:somatostatin 0.0017 0.0019 0.0078
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0009 0.0004 0.0014
Echinococcus granulosus sex peptide receptor 0.0017 0.0019 0.0078
Brugia malayi ecdysone receptor 0.0087 0.0163 0.053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0003
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0092 0.0173 0.2712
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0036 0.0584
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0009 0.0004 0.0014
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0035 0.0056 0.0771
Loa Loa (eye worm) hypothetical protein 0.0228 0.0451 0.1468
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0014 0.0183
Trypanosoma cruzi trans-sialidase, putative 0.0016 0.0019 0.0251
Brugia malayi hypothetical protein 0.0009 0.0004 0.0011
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0009 0.0004 0.0048
Echinococcus granulosus multidrug resistance protein 1 0.0008 0.0002 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0185 0.0362 0.118
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0009 0.0004 0.0014
Leishmania major basic transcription factor 3a, putative 0.0011 0.0009 0.0112
Trypanosoma cruzi trans-sialidase, putative 0.0016 0.0019 0.0251
Loa Loa (eye worm) CAMK/PKD protein kinase 0.015 0.0292 0.0949
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0185 0.0362 0.118
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0009 0.0004 0.0014
Loa Loa (eye worm) raf kinase 0.0046 0.008 0.0258
Brugia malayi GnHR receptor homolog 0.0017 0.0019 0.0062
Schistosoma mansoni atypical protein kinase C 0.0152 0.0295 0.0295
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0175 0.0343 0.14
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0016 0.0016
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0009 0.0004 0.0011
Echinococcus multilocularis G-protein coupled receptor, putative 0.0017 0.0019 0.0078
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0017 0.0019 0.0062
Entamoeba histolytica transcription factor BTF3, putative 0.0011 0.0009 0.0189
Trypanosoma cruzi spermidine synthase, putative 0.0363 0.0726 1
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0048 0.0083 0.0336
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0185 0.0362 0.1478
Brugia malayi nuclear receptor RXR 0.0098 0.0184 0.06
Plasmodium vivax basic transcription factor 3b, putative 0.0011 0.0009 0.0112
Loa Loa (eye worm) hypothetical protein 0.0077 0.0143 0.0464
Leishmania major mitochondrial DNA polymerase beta 0.0248 0.0492 0.6772
Brugia malayi RNA binding protein 0.0027 0.0041 0.013
Plasmodium vivax multidrug resistance protein 1, putative 0.0012 0.0009 0.012
Loa Loa (eye worm) CXXC zinc finger family protein 0.0012 0.001 0.0032
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0208 0.041 0.1673
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0185 0.0362 0.118
Echinococcus multilocularis serotonin receptor 0.0017 0.0019 0.0078
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0019 0.0078
Entamoeba histolytica hypothetical protein 0.0011 0.0009 0.0189
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0009 0.0004 0.0011
Mycobacterium tuberculosis Probable spermidine synthase SpeE (putrescine aminopropyltransferase) (aminopropyltransferase) (SPDSY) 0.0308 0.0615 1
Schistosoma mansoni hypothetical protein 0.0015 0.0016 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0185 0.0362 0.118
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0204
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0017 0.0019 0.0078
Echinococcus granulosus thyroid hormone receptor alpha 0.0087 0.0163 0.0664
Echinococcus granulosus neuropeptide s receptor 0.0017 0.0019 0.0078
Echinococcus granulosus tachykinin peptides receptor 99D 0.0017 0.0019 0.0078
Brugia malayi G-protein coupled receptor 0.0017 0.0019 0.0062
Loa Loa (eye worm) steroid hormone receptor 0.0185 0.0362 0.118
Entamoeba histolytica P-glycoprotein-5 0.0012 0.0009 0.0203
Echinococcus multilocularis transfer RNA-Lys 0.0024 0.0033 0.0134
Mycobacterium ulcerans putative regulatory protein 0.0024 0.0033 0.0536
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0185 0.0362 0.0362
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0009 0.0004 0.0014
Onchocerca volvulus 0.0009 0.0004 0.0005
Brugia malayi putative neuropeptide receptor 0.0017 0.0019 0.0062
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0087 0.0163 0.0664
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0063 0.0113 0.2599
Echinococcus granulosus high affinity choline transporter 1 0.0116 0.0221 0.0902
Onchocerca volvulus 0.0076 0.0139 0.0421
Trypanosoma brucei trans-sialidase, putative 0.0016 0.0019 0.0251
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0017 0.0019 0.0019
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0087 0.0163 0.0664
Onchocerca volvulus 0.0017 0.0019 0.0053
Toxoplasma gondii NADPH-glutathione reductase 0.0014 0.0014 0.0058
Schistosoma mansoni nuclear hormone receptor 0.0087 0.0163 0.0163
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0208 0.041 0.1673
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0009 0.0169
Echinococcus granulosus fmrfamide receptor 0.0017 0.0019 0.0078
Loa Loa (eye worm) hypothetical protein 0.0226 0.0448 0.1458
Schistosoma mansoni protein kinase C 0.005 0.0088 0.0088
Echinococcus granulosus transcription factor btf3 0.0011 0.0009 0.0033
Onchocerca volvulus 0.0012 0.0009 0.0022
Schistosoma mansoni amine GPCR 0.0017 0.0019 0.0019
Schistosoma mansoni microsomal glutathione s-transferase 0.1124 0.228 0.228
Loa Loa (eye worm) hypothetical protein 0.0107 0.0204 0.0662
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0009 0.0154
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0019 0.0078
Echinococcus multilocularis microtubule associated protein 2 0.0295 0.0588 0.2401
Plasmodium falciparum subtilisin-like protease 1 0.007 0.0129 0.1768
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0019 0.0078
Trypanosoma cruzi trans-sialidase, putative 0.0016 0.0019 0.0251
Onchocerca volvulus 0.0017 0.0019 0.0053
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0025 0.0036 0.0147
Echinococcus granulosus 7TM GPCR rhodopsin 0.0017 0.0019 0.0078
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0068 0.0926
Echinococcus granulosus RNA directed DNA polymerase 0.0078 0.0145 0.0589
Schistosoma mansoni amine GPCR 0.0017 0.0019 0.0019
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0185 0.0362 0.118
Echinococcus multilocularis N chimaerin 0.0046 0.008 0.0323
Echinococcus granulosus FTZ F1 alpha 0.0185 0.0362 0.1478
Trypanosoma brucei trans-sialidase 0.0016 0.0019 0.0251
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0009 0.0004 0.0014
Brugia malayi RE15519p 0.0017 0.0019 0.0062
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0017 0.0019 0.0019
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0017 0.0019 0.0062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0087 0.0163 0.053
Brugia malayi Peroxidasin 0.0012 0.001 0.003
Brugia malayi Ras association domain family 1 isoform A 0.0046 0.008 0.0258
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0046 0.008 0.0079
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.008 0.0079
Schistosoma mansoni inositol transporter 0.0453 0.0911 0.0911
Echinococcus granulosus sterol regulatory element binding protein 0.0055 0.0097 0.0395
Brugia malayi Matrixin family protein 0.0038 0.0063 0.0204
Echinococcus multilocularis alkaline phosphatase 0.0208 0.041 0.1673
Loa Loa (eye worm) hypothetical protein 0.0087 0.0163 0.053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0104 0.0197 0.0641
Schistosoma mansoni rac gtpase activating protein 0.0046 0.008 0.0079
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0009 0.0004 0.0003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0124 0.2012
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0009 0.0004 0.0081
Trypanosoma cruzi spermidine synthase, putative 0.0363 0.0726 1
Loa Loa (eye worm) hypothetical protein 0.0185 0.0362 0.118
Brugia malayi RhoGAP domain containing protein 0.0046 0.008 0.0258
Loa Loa (eye worm) hypothetical protein 0.0102 0.0194 0.0632
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Loa Loa (eye worm) animal heme peroxidase 0.0009 0.0004 0.0011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0185 0.0362 0.1478
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0019 0.0078
Mycobacterium ulcerans hydrolase 0.0047 0.008 0.1298
Onchocerca volvulus 0.0009 0.0004 0.0006
Trypanosoma cruzi trans-sialidase, putative 0.0016 0.0019 0.0251
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0019 0.0019
Echinococcus granulosus neuropeptide FF receptor 2 0.0017 0.0019 0.0078
Onchocerca volvulus 0.0009 0.0004 0.0006
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0009 0.0004 0.0014
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0009 0.0036
Brugia malayi hypothetical protein 0.0009 0.0004 0.0011
Brugia malayi hypothetical protein 0.0017 0.0019 0.0062
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0009 0.0004 0.0011
Trypanosoma brucei spermidine synthase 0.0363 0.0726 1
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0097 0.2233
Mycobacterium tuberculosis Probable reductase 0.0092 0.0173 0.2712
Echinococcus granulosus serotonin receptor 0.0017 0.0019 0.0078
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.0052
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0048 0.0083 0.0336
Schistosoma mansoni opsin-like receptor 0.0017 0.0019 0.0019
Brugia malayi hypothetical protein 0.0017 0.0019 0.0062
Echinococcus multilocularis protein kinase c eta type 0.0046 0.008 0.0323
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0008 0.0002 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.002 0.0025 0.0101
Loa Loa (eye worm) AGC/PKN protein kinase 0.0048 0.0083 0.0268
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0048 0.0083 0.0336
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0124 0.2012
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Onchocerca volvulus 0.0185 0.0362 0.1104
Schistosoma mansoni loxhd1 0.0217 0.0429 0.0428
Brugia malayi Steroid receptor seven-up type 2 0.0185 0.0362 0.118
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0016 0.0016
Loa Loa (eye worm) animal heme peroxidase 0.001 0.0006 0.0019
Loa Loa (eye worm) hypothetical protein 0.0098 0.0184 0.06
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0016 0.0016
Plasmodium falciparum spermidine synthase 0.0363 0.0726 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0087 0.0163 0.0493
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0014 0.0014 0.0217
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.0019
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0025 0.0036 0.0117
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0185 0.0362 0.118
Trypanosoma cruzi spermidine synthase, putative 0.0363 0.0726 1
Brugia malayi steroid hormone receptor 0.0185 0.0362 0.118
Echinococcus multilocularis high affinity choline transporter 1 0.0116 0.0221 0.0902
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0188 0.037 0.1203
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0009 0.0004 0.0081
Loa Loa (eye worm) hypothetical protein 0.0098 0.0184 0.06
Brugia malayi hypoxia-induced factor 1 0.0099 0.0187 0.0607
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Entamoeba histolytica P-glycoprotein-2 0.0012 0.0009 0.0203
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0003
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0017 0.0019 0.0062
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0048 0.0083 0.0268
Echinococcus granulosus glycoprotein Antigen 5 0.0015 0.0016 0.0065
Brugia malayi p70 ribosomal S6 kinase beta 0.0048 0.0083 0.0268
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0009 0.0169
Echinococcus granulosus nuclear receptor nhr 48 0.0087 0.0163 0.0664
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.002 0.0025 0.0025
Onchocerca volvulus 4.1 G protein, putative homolog 0.0009 0.0004 0.0006
Echinococcus multilocularis Niemann Pick C1 protein 0.0055 0.0097 0.0395
Trichomonas vaginalis abcb9, putative 0.0012 0.0009 0.0169
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0117 0.0225 0.3094
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0028
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0014 0.0014 0.0076
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.005 0.0087 0.0281
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0019 0.0061
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0016 0.0016
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0117 0.0225 0.3094
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Echinococcus multilocularis protein patched 0.0055 0.0097 0.0395
Loa Loa (eye worm) ICD-1 protein 0.0011 0.0009 0.0026
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0019 0.0078
Brugia malayi C1-like domain containing protein 0.015 0.0292 0.0949
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.002 0.0025 0.0101
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Onchocerca volvulus Phospholipase A2 homolog 0.0496 0.0999 0.3054
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0009 0.0036
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0017 0.0019 0.0078
Echinococcus granulosus N chimaerin 0.0046 0.008 0.0323
Trichomonas vaginalis AGC family protein kinase 0.0048 0.0083 0.1894
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0092 0.0173 0.2712
Echinococcus granulosus neuropeptide receptor 0.0017 0.0019 0.0078
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0017 0.0019 0.0078
Brugia malayi latrophilin 2 splice variant baaae 0.0011 0.0008 0.0024
Brugia malayi TAR-binding protein 0.0027 0.0041 0.013
Schistosoma mansoni nuclear hormone receptor 0.0185 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0055 0.0097 0.0315
Schistosoma mansoni inositol transporter 0.0453 0.0911 0.0911
Brugia malayi hypothetical protein 0.0017 0.0019 0.0062
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0014 0.0183
Schistosoma mansoni neuropeptide receptor 0.0017 0.0019 0.0019
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0019 0.0078
Onchocerca volvulus 0.0017 0.0019 0.0053
Brugia malayi hypothetical protein 0.0217 0.0429 0.1396
Echinococcus granulosus hypothetical protein 0.0017 0.0019 0.0078
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Echinococcus granulosus serine:threonine protein kinase N2 0.0048 0.0083 0.0336
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0087 0.0163 0.053
Trypanosoma brucei RNA helicase, putative 0.0041 0.0069 0.0941
Brugia malayi hypothetical protein 0.0009 0.0004 0.0011
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0015 0.0016 0.0065
Loa Loa (eye worm) hypothetical protein 0.0046 0.008 0.0258
Schistosoma mansoni nuclear receptor 0.0087 0.0163 0.0163
Loa Loa (eye worm) AGC/NDR protein kinase 0.0048 0.0083 0.0268
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0014 0.0183
Schistosoma mansoni hypothetical protein 0.0217 0.0429 0.0428
Trichomonas vaginalis AGC family protein kinase 0.0051 0.009 0.2059
Brugia malayi conserved hypotetical protein 0.0087 0.0163 0.053
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0019 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0185 0.0362 0.118
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0014 0.0183
Brugia malayi glutathione reductase 0.004 0.0068 0.0219
Loa Loa (eye worm) neuropeptide F receptor 0.0017 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0149 0.0289 0.094
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Schistosoma mansoni transcription factor btf3 0.0011 0.0009 0.0008
Brugia malayi Sodium:solute symporter family protein 0.0116 0.0221 0.072
Brugia malayi Protein kinase domain containing protein 0.0051 0.009 0.0291
Onchocerca volvulus 0.0009 0.0004 0.0006
Brugia malayi hypothetical protein 0.0087 0.0163 0.053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0035 0.0056 0.0771
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0008 0.0002 0.0003
Onchocerca volvulus 0.0009 0.0004 0.0006
Echinococcus granulosus dro:myosuppressin receptor 0.0017 0.0019 0.0078
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0082 0.0153 0.0498
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.004 0.0068 0.0966
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0014 0.0014 1
Loa Loa (eye worm) trypsin family protein 0.0015 0.0016 0.0052
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0124 0.0124
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0012 0.001 0.0039
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0217 0.0429 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0009 0.0004 0.0014
Echinococcus multilocularis G protein coupled receptor 139 0.0017 0.0019 0.0078
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0009 0.0004 0.0003
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0025 0.0036 0.0495
Brugia malayi nuclear hormone receptor 0.1509 0.3067 1
Toxoplasma gondii thioredoxin reductase 0.004 0.0068 0.0295
Brugia malayi Animal haem peroxidase family protein 0.0009 0.0004 0.0011
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0019 0.0259
Echinococcus granulosus orexin receptor type 2 0.0017 0.0019 0.0078
Echinococcus multilocularis myotubularin protein 13 0.005 0.0087 0.0352
Onchocerca volvulus 0.0009 0.0004 0.0005
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0009 0.0004 0.0014
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0185 0.0362 0.1478
Brugia malayi Nuclear hormone receptor-like 1 0.0185 0.0362 0.118
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.001 0.0006 0.0018
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0083 0.0082
Giardia lamblia Fructose-bisphosphate aldolase 0.0217 0.0429 1
Echinococcus multilocularis Diacylglycerol kinase theta 0.0046 0.008 0.0323
Echinococcus granulosus serine:threonine protein kinase N2 0.0092 0.0172 0.0701
Onchocerca volvulus 0.0009 0.0004 0.0006
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0016 0.0019 0.0058
Onchocerca volvulus 0.005 0.0088 0.0263
Entamoeba histolytica PH domain containing protein kinase, putative 0.0095 0.0179 0.417
Echinococcus granulosus neuropeptide receptor A26 0.0017 0.0019 0.0078
Loa Loa (eye worm) doublecortin family protein 0.0217 0.0429 0.1396
Brugia malayi neuropeptide F receptor 0.0017 0.0019 0.0062
Loa Loa (eye worm) TAR-binding protein 0.0027 0.0041 0.013
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0208 0.041 0.1673
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.0133 0.0257 0.0257
Onchocerca volvulus 0.0024 0.0033 0.0096
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0016 0.0019 0.0251
Mycobacterium ulcerans hypothetical protein 0.0131 0.0252 0.4096
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0016 0.0016
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0019 0.0019
Echinococcus multilocularis multidrug resistance protein 1 0.0012 0.0009 0.0036
Loa Loa (eye worm) MH2 domain-containing protein 0.009 0.0169 0.0551
Echinococcus granulosus Protein kinase C brain isozyme 0.0175 0.0343 0.14
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0092 0.0173 0.2712
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.0019
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0009 0.0004 0.0014
Trichomonas vaginalis adenylate cyclase, putative 0.0008 0.0002 0.0003
Echinococcus granulosus protein kinase c iota type 0.0148 0.0287 0.1171
Trichomonas vaginalis AGC family protein kinase 0.0051 0.009 0.2059
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Schistosoma mansoni hypothetical protein 0.0036 0.0058 0.0058
Echinococcus granulosus microsomal glutathione S transferase 3 0.1124 0.228 0.931
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0019 0.0078
Schistosoma mansoni tar DNA-binding protein 0.0027 0.0041 0.004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Brugia malayi Trypsin family protein 0.0015 0.0016 0.0052
Schistosoma mansoni myosin xvIII 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0046 0.008 0.0258
Echinococcus multilocularis dro:myosuppressin receptor 0.0017 0.0019 0.0078
Echinococcus granulosus C2 calcium dependent membrane targeting 0.005 0.0088 0.0357
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0009 0.0169
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0208 0.041 0.1673
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0016 0.0019 0.0251
Loa Loa (eye worm) hypothetical protein 0.0185 0.0362 0.118
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0009 0.0169
Trypanosoma brucei rac serine-threonine kinase, putative 0.0051 0.009 0.1232
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0362 0.0724 0.2359
Echinococcus multilocularis roundabout 2 0.0008 0.0002 0.0005
Brugia malayi hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Echinococcus granulosus neuropeptide receptor 0.0017 0.0019 0.0078
Brugia malayi CXXC zinc finger family protein 0.0012 0.001 0.0032
Echinococcus multilocularis ecdysone induced protein 78C 0.0185 0.0362 0.1478
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0014 0.0014 0.0217
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0015 0.0016 0.0065
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0048 0.0082 0.0335
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0185 0.0362 0.1478
Loa Loa (eye worm) hypothetical protein 0.0496 0.0999 0.3255
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0139 0.0269 0.1096
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Schistosoma mansoni serine/threonine kinase 0.0048 0.0083 0.0082
Onchocerca volvulus 0.0017 0.0019 0.0053
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.001 0.0005 0.0062
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0009 0.0169
Echinococcus granulosus 7tm_1 domain containing protein 0.0017 0.0019 0.0078
Schistosoma mansoni single-minded 0.0032 0.005 0.005
Loa Loa (eye worm) hypoxia-induced factor 1 0.0099 0.0187 0.0607
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0083 0.0154 0.0501
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Brugia malayi tailless protein 0.0087 0.0163 0.053
Brugia malayi G protein-coupled receptor 0.0017 0.0019 0.0062
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0078
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0106 0.0202 1
Schistosoma mansoni opsin-like receptor 0.0017 0.0019 0.0019
Entamoeba histolytica protein kinase, putative 0.0051 0.009 0.2088
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0017 0.0019 0.0053
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0116 0.0221 0.0902
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0019 0.0078
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0012 0.0009 0.6061
Loa Loa (eye worm) hypothetical protein 0.0046 0.008 0.0258
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Schistosoma mansoni aryl hydrocarbon receptor 0.0032 0.005 0.005
Onchocerca volvulus 0.0017 0.0019 0.0053
Brugia malayi nuclear receptor NHR-88 0.0185 0.0362 0.118
Loa Loa (eye worm) hypothetical protein 0.0087 0.0163 0.053
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0014 0.0014 0.0183
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0028
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0009 0.0004 0.0014
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0009 0.0036
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Brugia malayi RhoGAP domain containing protein 0.0046 0.008 0.0258
Brugia malayi GH02984p 0.0116 0.0221 0.072
Loa Loa (eye worm) spermidine synthase 0.0363 0.0726 0.2366
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0019 0.0019
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0019 0.0078
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.0133 0.0257 0.3541
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0025 0.0036 0.0449
Echinococcus multilocularis Mastin 0.0015 0.0016 0.0065
Loa Loa (eye worm) hypothetical protein 0.0038 0.0063 0.0204
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Brugia malayi nuclear receptor RXR 0.0087 0.0163 0.053
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.0052
Echinococcus multilocularis nuclear receptor nhr 48 0.0087 0.0163 0.0664
Plasmodium falciparum thioredoxin reductase 0.004 0.0068 0.0926
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0009 0.0169
Echinococcus granulosus Polycystic kidney disease protein 0.0217 0.0429 0.1748
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0017 0.0019 0.0078
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.002 0.0025 0.0101
Echinococcus granulosus Niemann Pick C1 protein 0.0055 0.0097 0.0395
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0133 0.0257 0.3541
Brugia malayi hypothetical protein 0.0176 0.0344 0.112
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0036 0.0058 0.0188
Plasmodium vivax thioredoxin reductase, putative 0.004 0.0068 0.0926
Brugia malayi Tachykinin-like peptides receptor 99D 0.0017 0.0019 0.0062
Echinococcus multilocularis neuropeptide receptor A26 0.0017 0.0019 0.0078
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0016 0.0019 0.0251
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0008 0.0002 0.0007
Schistosoma mansoni tar DNA-binding protein 0.0027 0.0041 0.004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0014 0.0183
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0009 0.0004 0.0048
Brugia malayi nuclear hormone receptor 0.0185 0.0362 0.118
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0009 0.0004 0.0003
Onchocerca volvulus Peroxidasin homolog 0.001 0.0006 0.0013
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0009 0.0169
Mycobacterium ulcerans hypothetical protein 0.0015 0.0016 0.0261
Echinococcus multilocularis serine:threonine protein kinase 38 0.0048 0.0083 0.0336
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0087 0.0163 0.0664
Schistosoma mansoni adenoreceptor 0.0017 0.0019 0.0019
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0017 0.0019 0.0019
Brugia malayi Animal haem peroxidase family protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0098 0.0184 0.06
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0014 0.0014 0.5
Trypanosoma brucei squalene monooxygenase, putative 0.0066 0.0119 0.1637
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0009 0.0169
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0048 0.0082 0.0335
Schistosoma mansoni lipoxygenase 0.0847 0.1715 0.1715
Schistosoma mansoni thyroid hormone receptor 0.0185 0.0362 0.0362
Brugia malayi AKH receptor 0.0017 0.0019 0.0062
Brugia malayi Dopamine receptor protein 2 0.0017 0.0019 0.0062
Echinococcus multilocularis serine:threonine protein kinase N2 0.0138 0.0267 0.1088
Onchocerca volvulus 0.0009 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Mycobacterium ulcerans spermidine synthase 0.0308 0.0615 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0092 0.0173 0.8573
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0098 0.0184 0.0184
Brugia malayi Cytochrome P450 family protein 0.0017 0.0019 0.0061
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0012 0.0009 0.0169
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0009 0.0004 0.0011
Brugia malayi neuropeptide F receptor 0.0017 0.0019 0.0062
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0009 0.0004 0.0003
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0185 0.0362 0.118
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0009 0.0004 0.0014
Trypanosoma cruzi trypanothione reductase, putative 0.0014 0.0014 0.0183
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0009 0.0004 0.0048
Brugia malayi sulfakinin receptor protein 0.0017 0.0019 0.0062
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0016 0.0019 0.0251
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0092 0.0173 0.2712
Loa Loa (eye worm) hypothetical protein 0.0087 0.0163 0.053
Loa Loa (eye worm) RasGEF domain-containing protein 0.0046 0.008 0.0258
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0009 0.0169
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0009 0.0004 0.0003
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0017 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0056 0.0099 0.0098
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0217 0.0429 1
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0009 0.0004 0.0003
Schistosoma mansoni hypothetical protein 0.0041 0.0069 0.0068
Echinococcus granulosus single minded 2 0.0024 0.0033 0.0134
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0102 0.0194 0.3058
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0012 0.0009 0.0169
Loa Loa (eye worm) hypothetical protein 0.0087 0.0163 0.053
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0068 0.0124 0.1703
Echinococcus multilocularis aryl hydrocarbon receptor 0.0008 0.0002 0.0007
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0017 0.0019 0.0062
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.001 0.0006 0.0018
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Onchocerca volvulus 0.0009 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0087 0.0163 0.053
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0014 0.0014 0.0013
Brugia malayi Pleckstrin Homology Domain 0.005 0.0087 0.0281
Loa Loa (eye worm) hypothetical protein 0.0133 0.0257 0.0838
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0217 0.0429 0.1396
Schistosoma mansoni nuclear receptor 0.0087 0.0163 0.0163
Brugia malayi G protein-coupled receptor F59B2.13 0.0017 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0116 0.0221 0.072
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0017 0.0019 0.0062
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0217 0.0429 1
Echinococcus multilocularis sex peptide receptor 0.0017 0.0019 0.0078
Onchocerca volvulus 0.0102 0.0194 0.0589
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0022
Brugia malayi hypothetical protein 0.0098 0.0184 0.06
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0003
Plasmodium vivax multidomain scavenger receptor, putative 0.0217 0.0429 0.5899
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0362 0.0724 0.0724
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Echinococcus granulosus protein kinase c eta type 0.0046 0.008 0.0323
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0185 0.0362 0.1478
Echinococcus multilocularis thyroid hormone receptor alpha 0.0185 0.0362 0.1478
Echinococcus granulosus raf serine:threonine protein kinase 0.0046 0.008 0.0323
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Onchocerca volvulus 0.0015 0.0016 0.0044
Onchocerca volvulus Bile acid receptor homolog 0.0185 0.0362 0.1104
Loa Loa (eye worm) matrixin family protein 0.0092 0.0174 0.0565
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0012 0.0009 0.0169
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0019 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0185 0.0362 0.118
Brugia malayi Doublecortin family protein 0.0217 0.0429 0.1396
Onchocerca volvulus 0.0017 0.0019 0.0053
Schistosoma mansoni unc-13 (munc13) 0.005 0.0088 0.0088
Brugia malayi Protein kinase c protein 2 0.0129 0.0249 0.0809
Leishmania major cytochrome p450-like protein 0.0017 0.0019 0.0259
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0185 0.0362 0.118
Schistosoma mansoni alkaline phosphatase 0.0208 0.041 0.041
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0016 0.0016
Brugia malayi Hr1 repeat family protein 0.0048 0.0083 0.0268
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0857 0.1736 0.1736
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0019 0.0078
Echinococcus granulosus roundabout 2 0.0008 0.0002 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.0343 0.0343
Loa Loa (eye worm) hypothetical protein 0.0152 0.0296 0.0963
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0009 0.0004 0.0014
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0017 0.0019 0.0062
Echinococcus granulosus RUN 0.0217 0.0429 0.1748
Echinococcus granulosus arachidonate 5 lipoxygenase 0.1207 0.2449 1
Echinococcus granulosus microtubule associated protein 2 0.0295 0.0588 0.2401
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0185 0.0362 0.118
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.001 0.0007 0.0025
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0046 0.008 0.0079
Treponema pallidum fructose-bisphosphate aldolase 0.0217 0.0429 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0185 0.0362 0.118
Echinococcus granulosus allatostatin A receptor 0.0017 0.0019 0.0078
Entamoeba histolytica protein kinase, putative 0.0048 0.0083 0.1923
Schistosoma mansoni hypothetical protein 0.0015 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Echinococcus multilocularis microsomal glutathione S transferase 3 0.1124 0.228 0.931
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0017 0.0019 0.0078
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.1607 0.3266 1
Onchocerca volvulus 0.0149 0.0289 0.0878
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0035 0.0056 0.0771
Loa Loa (eye worm) hypothetical protein 0.0115 0.0219 0.0712
Entamoeba histolytica protein kinase, putative 0.0051 0.009 0.2088
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0025 0.0036 0.0584
Echinococcus granulosus Nuclear hormone receptor HR96 0.0087 0.0163 0.0664
Onchocerca volvulus 0.0115 0.0219 0.0665
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0012 0.0009 0.0034
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0014 0.0014 0.0183
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0062
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0087 0.0163 0.0163
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0019 0.0078
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0185 0.0362 0.0362
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0019 0.0078
Brugia malayi Nuclear hormone receptor E75 0.0087 0.0163 0.053
Trypanosoma cruzi trans-sialidase, putative 0.0016 0.0019 0.0251
Onchocerca volvulus 0.0015 0.0016 0.0044
Echinococcus multilocularis g-protein coupled receptor 0.0017 0.0019 0.0078
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0087 0.0163 0.0664
Brugia malayi Dopamine receptor 0.0017 0.0019 0.0062
Echinococcus granulosus protein kinase c epsilon type 0.0188 0.037 0.1508
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0185 0.0362 0.118
Brugia malayi nuclear receptor NHR-88 0.0087 0.0163 0.053
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Brugia malayi Cytochrome P450 family protein 0.0017 0.0019 0.0061
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0011
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0185 0.0362 0.0362
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0017 0.0019 0.0019
Onchocerca volvulus 0.0009 0.0004 0.0006
Echinococcus granulosus lipoxygenase domain containing protein 0.0217 0.0429 0.1748
Echinococcus granulosus Protein patched homolog 1 0.0055 0.0097 0.0395
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0048 0.0083 0.0336
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0014 0.0014 0.0054
Leishmania major p-glycoprotein 0.0012 0.0009 0.012
Onchocerca volvulus 0.0038 0.0063 0.0187
Schistosoma mansoni alpha-1 adrenergic receptor 0.0017 0.0019 0.0019
Echinococcus granulosus peroxidasin 0.0012 0.001 0.0038
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0009 0.0036
Trypanosoma cruzi spermidine synthase, putative 0.0363 0.0726 1
Mycobacterium leprae PROBABLE HYDROLASE 0.0047 0.008 0.391
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0009 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.018 0.0353 0.115
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0453 0.0911 0.3718
Brugia malayi Variant SH3 domain containing protein 0.0046 0.008 0.0258
Schistosoma mansoni diacylglycerol kinase theta 0.0046 0.008 0.0079

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) nM Inhibitory activity of the compound against S-adenosyl-L-methionine decarboxylase was determined; NI means No inhibition ChEMBL. 7629810
IC50 (binding) nM Inhibition of Ornithine decarboxylase in rat liver; Not inhibited ChEMBL. 7629810
IC50 (binding) = 3 nM Inhibition of prokaryotic Escherichia coli Putrescine aminopropyltransferase was determined ChEMBL. 7629810
IC50 (binding) = 14 nM Inhibition of Putrescine aminopropyl transferase (PAPT) in rat liver ChEMBL. 7629810
IC50 (binding) = 750 nM Inhibition of Spermidine aminopropyltransferase (SAPT) in rat liver. ChEMBL. 7629810

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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